Willa Hsueh | Immunometabolism | Best Researcher Award

Prof. Willa Hsueh | Immunometabolism | Best Researcher Award

The Ohio State University | United States

Dr. Willa Hsueh is a leading researcher in endocrinology, diabetes, and metabolism, with a career spanning several decades of pioneering contributions to hormone regulation and metabolic disease. Her early research provided key insights into renin biochemistry and aldosterone metabolism, particularly focusing on inactive “big renin” forms and their activation mechanisms in normal and pathological conditions such as diabetic nephropathy. Dr. Hsueh’s investigations have significantly advanced the understanding of the renin-angiotensin-aldosterone system (RAAS) and its role in blood pressure regulation, sodium balance, and endocrine disorders. Her studies explored adrenal physiology, steroid metabolism, and hormonal responses to physiological and pharmacological stimuli, laying the groundwork for later research on cardiovascular and metabolic dysfunctions in diabetes. Through her interdisciplinary approach combining endocrinology, nephrology, and metabolism, she has elucidated biochemical pathways linking hormonal imbalances to metabolic diseases. Dr. Hsueh continues to lead impactful research in diabetes and metabolic regulation, contributing to translational advancements that bridge molecular mechanisms with clinical applications for improved patient outcomes in endocrine and metabolic disorders.

Profiles: Scopus | Orcid

Featured Publications:

Hsueh, W. A., Boonjaren, S., Stein, J., Baehler, H. R., Osgood, R. W., Cohen, S., Yashon, D., & Ferris, T. (1974). Effect of plasma sodium concentration on diluting segment sodium reabsorption. Kidney International, 5(1), 1–11.

Johnson, K. R., Hsueh, W. A., Glusman, S. M., & Arnett, F. C. (1976). Fibrous myopathy: A rheumatic complication of drug abuse. Arthritis & Rheumatism, 19(5), 923–926.

Hsueh, W. A., & Hsu, T. H. (1978). Thyrotoxicosis in a patient with secondary hypothyroidism. Southern Medical Journal, 71(9), 1174–1177.

Hsueh, W. A., Luetscher, J. A., Carlson, E., & Grislis, G. (1978). Big renin in plasma of healthy subjects on high-sodium intake. The Lancet, 1(8077), 1281–1284.

Hsueh, W. A., Hsu, T. H., & Federman, D. D. (1978). Endocrine features of Klinefelter’s syndrome. Medicine, 57(5), 447–461.

Hsueh, W. A., Luetscher, J. A., Carlson, E., Grislis, G., Elbaum, D., & Chavarri, M. (1978). A comparison of cold and acid activation of big renin and of inactive renin in normal plasma. Journal of Clinical Endocrinology and Metabolism, 47(4), 792–799.

Kelly Bosak | Stem Cell Research | Best Researcher Award

Dr. Kelly Bosak | Stem Cell Research | Best Researcher Award

University of Kansas Medical Center | United States

Dr. Kelly A. Bosak, PhD, APRN, ANP-BC, FHFSA, is a tenured Associate Professor at the University of Kansas Medical Center and a nationally recognized expert in heart failure care, nursing science, and implementation research. With a strong background in advanced practice nursing and nursing administration, Dr. Bosak has made significant contributions to interdisciplinary research focused on improving clinical outcomes in cardiology, rural health, and chronic disease management. Her peer-reviewed work spans high-impact journals such as The Journal of Cardiac Failure, Implementation Science, and The Journal for Nurse Practitioners, reflecting her leadership in both clinical practice and academic scholarship. Dr. Bosak has authored or co-authored over 30 peer-reviewed publications, with a Scopus h-index of 10, over 450 citations, and 32 documents indexed in major databases. She has played a pivotal role in national reports from the Heart Failure Society of America and led multiple implementation science projects aimed at integrating evidence-based interventions into routine care. Her current research emphasizes digital health innovation and workforce development in underserved communities. Dr. Bosak’s interdisciplinary collaborations and translational research continue to shape evidence-based practice and policy in cardiovascular nursing and advanced practice nursing education.

Profiles: Google Scholar | Scopus

Featured Publications:

  • “Return on Investment of a Nurse Practitioner Fellowship Program”

  • “Interprofessional Education for Improving Workforce Capacity to Treat COPD and Long COVID in Rural Communities”

  • “Shared Decision Making for the Pulmonary Artery Monitoring Device for Patients with Heart Failure”

  • “Implementation of a SmartPhrase for Exercise in the Electronic Health Record for Individuals with Heart Failure”

  • “Implementing a Standardized Workflow for Early Detection of Steroid-Induced Hyperglycemia in Allogeneic Stem Cell Transplant Recipients: A Quality Improvement Project”

  • “Team Science”

  • “Ceramides as Novel Biomarkers of Cardiometabolic Conditions”

  • “Heart Failure Epidemiology and Outcomes Statistics An Updated 2024 Report from the Heart Failure Society of America”

  • “Heart Failure Epidemiology and Outcomes Statistics, A Report of the Heart Failure Society of America”

  • “Implementation Mapping and Concept Mapping to Explore Guideline Implementation in the Heart Failure Clinic”

  • “Coordinating Resources for a Hybrid Effectiveness and Implementation Trial Across an Integrated Digital Network for Heart Failure”

  • “Creating a Standardized Approach to Program Evaluation in a Magnet Recognized Pediatric Hospital System”

 

 

 

Ali Alahmari | Stem Cell Transplantation | Best Researcher Award

Dr. Ali Alahmari | Stem Cell Transplantation | Best Researcher Award

Kfshrc | Saudi Arabia

Dr. Ali Alahmari is a distinguished consultant in Acute Leukemia, Hematology, Hematopoietic Stem Cell Transplantation (HSCT), and Cellular Therapy at King Faisal Specialist Hospital & Research Centre. He earned his MBBS degree from King Saud University and completed his internship at King Khalid University Hospital. He has held a key consultant position, contributing extensively to the advancement of cellular therapy and bone marrow transplantation in Saudi Arabia. Dr. Alahmari has made significant academic contributions to the field, particularly in hemato-hepatology and sickle cell disease. His research has focused on novel transplant approaches, including haploidentical stem cell transplantation after liver transplantation and donor impact in severe aplastic anemia. He has co-authored over 22 scientific documents, with his work accumulating more than 629 citations and earning an h-index of 12, reflecting the depth and influence of his research. His notable publications include titles such as Donor impact on allogeneic transplant outcomes with PTCy for severe aplastic anemia and Haplo-stem cell transplant post liver transplantation to cure sickle cell disease with related liver dysfunction.” Dr. Alahmari’s ongoing efforts continue to shape clinical best practices and research frameworks for hematologic disorders and transplantation medicine in the region.

Profile: Scopus

Featured Publications:

  • “Author Correction: Haplo-stem cell transplant post liver transplantation to cure sickle cell disease with related liver dysfunction: a case series”

  • “Donor impact on allogeneic transplant outcomes with PTCy for severe aplastic anemia: a study of the SAAWP EBMT”

  • “Emerging need for a hepato-hematology program for patients with sickle cell disease in Saudi Arabia”

  • “Haplo-stem cell transplant post liver transplantation to cure sickle cell disease with related liver dysfunction: a case series”

  • “Hematopoietic Stem Cell Transplantation in Sickle Cell Disease”

  • “Setting up a Chimeric Antigen Receptor T Cell Therapy Program: A Framework for Delivery from the Worldwide Network for Blood & Marrow Transplantation”

  • “Outcomes of human leukocyte antigen matched sibling transplant from consanguineous versus non-consanguineous parents, a single center experience”

Shuxin Han | Molecular Mechanisms Signaling | Best Researcher Award

Dr. Shuxin Han | Molecular Mechanisms Signaling | Best Researcher Award

Dr. Shuxin Han | Xinjiang University | China

Dr. Shuxin Han is a distinguished molecular biologist and professor at Xinjiang University, widely recognized for his pioneering work in hepatobiliary and metabolic biology. With a research career spanning over two decades, Dr. Han has made major contributions to understanding how Kruppel-like factors, especially KLF15, regulate endobiotic and xenobiotic metabolism, impacting drug detoxification and metabolic disease mechanisms. He earned his Ph.D. from Kent State University and has held prestigious positions at Harvard Medical School and Case Western Reserve University. His groundbreaking studies have been published in high-impact journals like Nature Metabolism and Nature Communications, with several articles naming him as first or corresponding author. In addition to research, Dr. Han serves as a reviewer for top-tier journals in pharmacology, hepatology, and clinical science. He is also an academic leader, currently shaping the next generation of scientific talent and metabolic disease research in China.

Publication Profile: 

Scopus

Education:

Dr. Shuxin Han began his academic journey in Animal Sciences, earning a bachelor’s degree from Anhui Agricultural University (1994–1998). He advanced to a research assistant role at Peking University (1999–2000), where he deepened his scientific foundation. He then moved to the U.S. to pursue a Master’s in Biology at Temple University (2000–2003), followed by a Ph.D. in Molecular Biology from Kent State University (2004–2009), focusing on metabolic biology and gene regulation. This progression from general animal sciences to highly specialized molecular biology reflects a systematic and deep commitment to biomedical research. His strong academic preparation laid the foundation for a research career investigating how transcriptional regulators impact health and disease. Dr. Han’s training spans world-class institutions across both China and the United States, equipping him with diverse scientific perspectives and techniques.

Experience:

Dr. Shuxin Han has accumulated rich research and academic experience over nearly 30 years. His early career included a pivotal research assistant role at Peking University, followed by advanced training in biology and molecular biology at Temple and Kent State Universities. He completed prestigious postdoctoral training at Harvard Medical School (2009–2012) and Case Western Reserve University (2012–2015), where he later became a Senior Research Associate (2015–2019). He returned to China in 2019 as a Researcher at the University of Science and Technology of China First Affiliated Hospital, simultaneously engaging in academic duties at the university until 2023. Currently, he serves as a Professor and Academic Leader at Xinjiang University. Throughout his career, Dr. Han has built strong international collaborations, led research groups, and guided innovative projects in metabolic biology, demonstrating his leadership, research excellence, and academic mentorship capabilities.

Research Focus:

Dr. Shuxin Han’s research centers on the molecular regulation of metabolism, particularly focusing on the hepatobiliary and gastrointestinal systems. His work has elucidated the critical role of the Kruppel-like factor (KLF) family, especially KLF15, in controlling endobiotic and xenobiotic metabolism (EXM). These pathways govern how the body metabolizes both internal compounds and external substances like drugs. Dr. Han’s studies have shown that KLF15 acts as a master regulator, influencing drug resistance, liver injury, and metabolic homeostasis. His discoveries offer new insight into personalized medicine and treatment for metabolic disorders and drug-related toxicities. With numerous first-author and corresponding-author publications in journals such as Nature Metabolism, Nature Communications, and Drug Metabolism and Disposition, his work has significantly impacted both fundamental science and clinical applications. He is also active in peer-reviewing for top-tier journals and is recognized for his leadership in translational research.

Publications Top Notes:

  1. Unveiling KLF15 as the Key Regulator of Cyclosporine A Metabolism and Adverse EffectsDrug Metabolism and Disposition, 2025

  2. Distribution and Functional Significance of KLF15 in Mouse CerebellumMolecular Brain, 2025

  3. Personalized Statin Therapy: Targeting Metabolic ProcessesHeliyon, 2025

  4. Current Status and New Directions for Hepatocellular Carcinoma DiagnosisLiver Research, 2024

  5. KLF15-Cyp3a11 Axis Regulates Rifampicin-Induced Liver InjuryDrug Metabolism and Disposition, 2024

  6. Advancing Drug Delivery and Bioengineering in Liver ResearchBioengineering and Translational Medicine, 2024

  7. Advances in IL-7 Research on Tumor TherapyPharmaceuticals, 2024 (Co-author)

  8. Pathogenic Mechanisms in Alcoholic Liver DiseaseJournal of Translational Medicine, 2023

  9. Beta-Hydroxybutyrate Effects on iPSC-Derived Cardiac MyocytesBiomolecules, 2022

  10. Interactions Between Intestinal Flora and Bile AcidsInternational Journal of Molecular Sciences, 2022 (Corresponding author)

Conclusion:

In conclusion, Dr. Shuxin Han is a highly deserving candidate for the Best Researcher Award. His pioneering work on KLF15 and metabolic regulation has reshaped fundamental understanding in the field of hepatobiliary biology and pharmacology. His academic background, research productivity, international experience, and editorial service all reflect a well-rounded and impactful scientist. While there is room to increase clinical translation and international engagement, the depth, originality, and consistency of his research make him a strong contender for this recognition. Honoring Dr. Han with this award would acknowledge a career dedicated to scientific advancement with substantial implications for human health and drug therapy.

Amr Hanbali | Therapeutic use of Cellular therapy in cancer treatment | Best Researcher Award

Assoc. Prof. Dr. Amr Hanbali | Therapeutic use of Cellular therapy in cancer treatment | Best Researcher Award

Assoc. Prof. Dr. Amr Hanbali | King Faisal Specialist Hospital & Research Center | Saudi Arabia

Dr. Amr AlHanbali is a dual-certified Hematology and Oncology consultant with over 18 years of experience in malignant and benign hematological conditions. Based at King Faisal Specialist Hospital & Research Center in Riyadh, Saudi Arabia, he specializes in hematologic malignancies and stem cell transplantation. Dr. AlHanbali previously served as a senior staff physician and Associate Fellowship Program Director at Henry Ford Health System in Detroit, Michigan. Recognized for his academic involvement, he holds teaching appointments at Wayne State University and Alfaisal University. Known for his dedication to clinical mentorship, he has trained numerous medical students, residents, and fellows. He is actively involved in research and is a member of several prestigious medical organizations including the American Society of Hematology and American Society of Clinical Oncology. With expertise ranging from bone marrow procedures to managing complex hematologic disorders, Dr. AlHanbali is a respected leader in the field of hematology and stem cell transplantation.

Publication Profile:

Scopus

Strengths for the Award:

  1. Extensive Research Contribution

    • Over 17 peer-reviewed publications, including impactful case reports, national guidelines, and original research in hematology, oncology, and stem cell transplantation.

    • Active contributor to national guidelines on multiple myeloma, reflecting leadership in shaping national healthcare standards in KSA.

  2. Dual Academic and Clinical Roles

    • Combines academic excellence (as faculty at Wayne State University and Alfaisal University) with hands-on clinical expertise at a premier institution (King Faisal Specialist Hospital & Research Center).

  3. Innovative Focus in Hematology and Transplantation

    • Research into underexplored areas such as hepatitis B reactivation post-rituximab, genetic donor match outcomes, and therapies for AL amyloidosis.

  4. International Exposure and Leadership

    • Experience across the U.S. and Saudi Arabia, influencing programs in both systems.

    • Played a key role in training and selecting future hematology-oncology fellows in the U.S.

  5. Mentorship and Capacity Building

    • Mentored numerous trainees, enhancing research culture among younger clinicians.

Areas for Improvement:

  1. Higher Impact Publications Needed

    • While the volume and variety of research are commendable, more publications in top-tier journals (NEJM, Lancet, Blood, JCO) could boost citation impact and visibility.

  2. Research Grants and Collaborative Trials

    • Pursuing multicenter studies, international collaborations, or industry-sponsored clinical trials would further elevate his profile and expand research funding sources.

  3. Technological Innovation/Patents

    • Exploring biotech innovation, AI in diagnostics, or cellular therapy patents could position him among the top medical innovators.

Education:

Dr. Amr AlHanbali completed his Bachelor of Medicine and Surgery from the University of Jordan in 1999. He pursued medical training in the United States, starting with an internal medicine residency (2001–2004) at Henry Ford Health System, Detroit. He continued his specialization with a fellowship in Hematology and Oncology (2004–2007) at the same institution. During his training, he also undertook elective rotations in Pediatric Cardiology and Gastroenterology at the University of Texas Medical Branch, Galveston, further enriching his academic exposure. He is certified by the American Board of Internal Medicine in Internal Medicine (2004), Hematology (2007), and Oncology (2007). Dr. AlHanbali holds academic titles as a Clinical Assistant Professor at Wayne State University, Detroit, and Adjunct Associate Professor at Alfaisal University, Riyadh. His educational background reflects a strong foundation in internal medicine, with a deep focus on hematology and oncology, further supported by teaching and research excellence.

Experience:

Dr. AlHanbali’s clinical career spans over 18 years, currently serving as Hematology and Stem Cell Transplant Consultant at King Faisal Specialist Hospital & Research Center in Riyadh since 2013. Prior to this, he held multiple leadership roles at Henry Ford Health System, Detroit, including Senior Staff Physician and Associate Fellowship Program Director (2007–2013). His medical expertise covers the diagnosis and treatment of a wide range of hematologic malignancies such as leukemia, lymphoma, multiple myeloma, and myeloproliferative disorders. Dr. AlHanbali also has extensive experience in stem cell transplantation, intrathecal chemotherapy, and bone marrow biopsy. He has been instrumental in resident selection and curriculum development for fellowship programs in hematology and oncology. His work bridges clinical excellence with academic mentorship, guiding numerous trainees and junior physicians. In addition to patient care, he is involved in clinical guideline development and research, particularly in the field of multiple myeloma and transplant outcomes.

Research Focus:

Dr. Amr AlHanbali’s research is centered on hematologic malignancies, particularly multiple myeloma, lymphoma, leukemia, and stem cell transplantation. His work explores novel therapeutic approaches, transplant outcomes, disease progression, and treatment-related complications. He has contributed significantly to research on hepatitis B reactivation, chemotherapy-induced toxicities, and the protective role of comorbidities like diabetes in cancer metastasis. As an active member of the Saudi Myeloma Working Group, he has co-authored national guidelines for both newly diagnosed and relapsed/refractory multiple myeloma. His studies also examine health disparities in cancer care, including outcomes among African American populations and the impact of familial genetics in donor matches. With over a dozen peer-reviewed publications and case reports in high-impact journals, Dr. AlHanbali continues to push forward understanding in clinical hematology and oncology. He combines bedside insights with academic rigor to shape evidence-based practice and improve treatment outcomes in cancer and transplant medicine.

Publications Top Notes:

  1.  Mediastinal Hematoma With SVC Syndrome From A Central Venous Catheter Insertion – CHEST, 2003

  2.  Diabetes Has Protective Effect Against Metastasis in Non-Small Cell Lung Cancer – Arch Intern Med, 2007

  3.  Delayed Hepatitis B Viral Replication Post-Rituximab & Fludarabine in Waldenstrom Macroglobulinemia – Am J Hematol, 2007

  4.  Acute Pancreatitis Induced by Adult Precursor B-cell ALL – South Med J, 2007

  5.  Hypersensitivity Reaction of Mylotarg with Platelet Transfusion – Am J Health Syst Pharm, 2007

  6.  Incidence of Hepatitis B Reactivation after Rituximab Therapy – Am J Hematol, 2009

  7. Outcomes After Auto-SCT in African Americans with Multiple Myeloma – Bone Marrow Transplant, 2009

  8.  HER-2 Status May Change in Recurrent Breast Cancer – Cancer Research, 2009

  9.  Compartment Syndrome as Presentation of Chronic Myelogenous Leukemia – J Gen Intern Med, 2010

  10.  Use of Insulin and its Effect on Survival in NSCLC – J Clin Oncol, 2009

Conclusion:

Dr. Amr AlHanbali demonstrates a stellar blend of clinical expertise, research productivity, academic mentorship, and leadership in hematology and oncology. His research contributions have practical implications in areas such as multiple myeloma, leukemia, transplant immunology, and chemotherapy safety.

He is highly deserving of recognition and stands out as a top contender for a Best Researcher Award, particularly in the categories of clinical research excellence, translational hematology, and medical education integration with research.

Chun Yan | Stem Cell Research | Best Researcher Award

Dr. Chun Yan | Stem Cell Research | Best Researcher Award

Dr. Chun Yan, Department of Thoracic Surgery, Zhongshan Hospital of Xiamen University, China

Dr. Yan Chun is an Attending Physician at the School of Medicine/Zhongshan Hospital, Xiamen University. With a solid foundation in clinical medicine and surgery, Dr. Chun brings over a decade of experience in thoracic oncology and AI-driven medical research. After earning a Bachelor’s degree from Fujian Medical University, he pursued his Master’s in Surgery at Shanghai Jiao Tong University. Since 2018, Dr. Chun has contributed significantly to clinical practice, medical innovation, and academic research. His current focus includes AI-assisted diagnosis, radiogenomics, and the biomechanics of thoracic surgery. A recognized member of the Minimally Invasive Thoracic Oncology Committee under the Fujian Primary Health Association, he has received multiple accolades for his pioneering work in esophageal cancer therapy. Dr. Chun’s commitment to precision medicine and integration of AI in healthcare highlights his suitability for prestigious research honors and positions him as a leader in translational medical research in China.

Publication Profile: 

Scopus

✅ Strengths for the Award:

  1. Strong Academic Foundation: Dr. Yan Chun holds a Master’s degree in Surgery from Shanghai Jiao Tong University and a Bachelor’s degree in Clinical Medicine, ensuring a robust foundation in both research and clinical practice.

  2. Innovative Research: He leads and participates in cutting-edge projects that integrate AI, radiogenomics, and biomechanical modeling, reflecting a multidisciplinary and forward-thinking approach.

  3. Recognized Excellence: His work has been honored with regional innovation and scientific progress awards, demonstrating tangible contributions to thoracic oncology.

  4. Clinical Expertise: With 7+ years of medical experience, including as an attending physician, he bridges practical medicine with impactful research.

  5. Leadership Role: Serving on a professional committee in minimally invasive thoracic oncology highlights his thought leadership within his specialty.

🧠 Areas for Improvement:

  1. Expanded Publication Record: While impactful, Dr. Chun’s publication portfolio would benefit from a broader presence in international, high-impact journals to boost academic visibility.

  2. International Collaboration: Engaging in cross-border research partnerships could enhance both innovation scope and influence.

  3. Grant Scale: Existing grants are modest in size. Applying for national-level or larger competitive grants could support more ambitious projects.

  4. Mentorship and Training: Documenting roles in mentoring junior researchers or medical students would strengthen his academic leadership profile.

🎓 Education:

Dr. Yan Chun’s academic journey began with a Bachelor of Clinical Medicine (MBBS) from Fujian Medical University (2010–2015), where he gained fundamental clinical knowledge and medical training. He then advanced his specialization in surgery by completing a Master of Surgery (MS) at Shanghai Jiao Tong University (2015–2018), one of China’s top medical institutions. His education emphasized evidence-based clinical practice, surgical skills, and research methodology. During his postgraduate studies, he was actively involved in academic projects, laying a strong foundation for his later research in thoracic oncology and artificial intelligence in medicine. This robust educational background equips him with interdisciplinary expertise, bridging clinical medicine, surgical techniques, and research innovation—especially in radiogenomics and perioperative therapies for esophageal cancer. His training reflects both academic rigor and a forward-looking approach to integrating emerging technologies with healthcare delivery, making him well-prepared to drive impactful research initiatives.

💼 Experience:

Dr. Yan Chun has held progressive roles at Zhongshan Hospital, Xiamen University since 2018. Starting as a Physician (2018–2023), he delivered comprehensive clinical care while engaging in translational research projects. Since July 2023, he has been serving as an Attending Physician, contributing to surgical excellence and AI-assisted diagnostic strategies in thoracic oncology. His hands-on clinical experience is complemented by leadership in grant-funded research, particularly in predictive modeling and biomechanics. Dr. Chun’s involvement in multi-disciplinary teams, collaborations with AI scientists, and contributions to surgical innovation have advanced the care standards in thoracic surgery. He has also actively contributed to institutional and provincial-level scientific programs, showcasing his capability in both practical medicine and medical research. His work stands at the intersection of clinical practice and innovation, and he remains committed to improving outcomes for patients with complex thoracic conditions through precision diagnostics and minimally invasive techniques.

🏅 Awards and Honors:

Dr. Yan Chun has received multiple accolades recognizing his innovative contributions to thoracic oncology and surgical AI. His project, “AI-Assisted Precision Perioperative Individualized Therapy for Esophageal Cancer”, was selected as one of the Top Ten Innovations of the Year by the Xiamen Hospital Association, highlighting its impact on personalized medicine. Another landmark project, “Precision Diagnosis and Treatment Paradigm for Esophageal Squamous Cell Carcinoma Driven by AI and Multi-Omics Integration”, earned him the Third Prize for Scientific and Technological Progress from the Fujian Anti-Cancer Association, underscoring his leadership in advanced cancer care. His awards reflect not only clinical innovation but also excellence in multi-disciplinary research. These honors are a testament to his ability to bridge clinical needs with technological advancements, demonstrating vision, technical skill, and translational impact. They position him as a high-impact researcher contributing meaningfully to China’s evolving healthcare landscape.

🔬 Research Focus:

Dr. Yan Chun’s research is primarily centered on the integration of artificial intelligence, radiogenomics, and thoracic oncology. He leads a government-funded project investigating deep learning-based predictive models for lymph node metastasis and prognosis in esophageal cancer, leveraging imaging-genomics to improve pre- and post-operative decision-making. He also contributed to biomechanical analysis of the NUSS procedure for pectus excavatum, applying finite element modeling to improve surgical outcomes. His work merges clinical data science, image processing, and genomics, aiming to build personalized treatment pathways and enhance minimally invasive approaches. Dr. Chun’s interdisciplinary approach reflects a deep understanding of both computational technologies and real-world clinical challenges. His ambition is to develop AI-powered platforms that augment oncological diagnostics and optimize surgical interventions. Through a combination of hands-on experience and research rigor, he is at the forefront of precision medicine in thoracic surgery, striving for innovation that is both data-driven and patient-centered.

📚 Publications Top Notes:

📖 Association between per- and polyfluoroalkyl substances exposure and prevalence of chronic obstructive pulmonary disease: The mediating role of serum albuminScience of the Total Environment, 2024 🌱🫁

🧾 Conclusion:

Dr. Yan Chun demonstrates exceptional promise and maturity as a clinical researcher whose work lies at the confluence of AI, precision medicine, and thoracic surgery. His contributions to the diagnosis and treatment of esophageal cancer through radiogenomic modeling and minimally invasive techniques are both innovative and clinically meaningful. Backed by professional recognition and a strong clinical research ethic, Dr. Chun is a worthy candidate for the Best Researcher Award. With expanded international presence and high-impact publications, he is poised to become a leading figure in the global thoracic oncology research community.

Mohammad reza Atashzar | Cancer stem cell | Best Researcher Award

Dr. Mohammad reza Atashzar | Cancer stem cell | Best Researcher Award

Dr. Mohammad reza Atashzar, Dep of immunology, Fasa university of medical sciences ( FUMS ), Iran

Dr. Mohammad Reza Atashzar is an Assistant Professor in the Department of Immunology at Fasa University of Medical Sciences (FUMS), Iran. With an enduring passion for tumor immunology, stem cells, vaccine design, and immunotherapy, he has made significant contributions through both basic and translational research. Dr. Atashzar earned his PhD in Immunology from Shahid Beheshti University of Medical Sciences and has since engaged in teaching, mentoring, and publishing extensively in high-impact journals such as The Lancet Oncology, Frontiers in Immunology, and Current Molecular Medicine. His innovative research spans exosome-based therapy, cancer biomarkers, cytokine profiling, and radiogenomics. Dr. Atashzar has also contributed to international collaborations across Germany, Finland, and the UK, showcasing a global outlook in biomedical science. An awardee of the KAI 2022 International Travel Grant and recognized as the Top Researcher at FUMS in 2021, he remains deeply committed to advancing immunological sciences for clinical and therapeutic benefit.

Publication Profile: 

Orcid

Google Scholar

✅ Strengths for the Award:

  1. Extensive Research Contributions
    Dr. Atashzar has authored numerous peer-reviewed publications in reputable journals including The Lancet Oncology, Frontiers in Immunology, Current Molecular Medicine, and Computers in Biology and Medicine. His work spans critical fields like cancer immunology, exosome therapy, stem cell immunomodulation, and vaccine research.

  2. High-Impact Publications
    Several of his papers have significant citation counts—556 for Frontiers in Immunology, 284 for Journal of Cellular Physiology, and 207 for The Lancet Oncology, reflecting strong influence and relevance in the scientific community.

  3. International Recognition and Collaborations
    He has participated in international conferences (UK, China, Korea, Denmark, Spain, Italy) and collaborated with global institutions such as the University of Helsinki, University of Kiel, and GBD Collaborators, demonstrating a global research footprint.

  4. Innovation and Patents
    He has contributed to translational science through a published book on immunopharmacology and a pending patent for a microbiology loop sterilizer device, showing practical application of his research.

  5. Awards and Editorial Involvement
    Recognized with the International Travel Award (KAI 2022) and Top Researcher of FUMS (2021), and serving on editorial boards of scientific journals—further affirming his active role in academic development and peer review.

  6. Interdisciplinary Research Scope
    His research merges clinical immunology, oncology, AI-based prognostic tools, and cellular therapy, making his work not only innovative but also future-oriented.

⚠️ Areas for Improvement:

  1. Increase in First or Senior Author Publications
    While his contributions are numerous, strengthening his authorship role in key studies would amplify his recognition as a principal investigator.

  2. Patent Commercialization & Technology Transfer
    Moving from patent design to real-world implementation or licensing could significantly raise the translational value of his research.

  3. Higher Grant Involvement
    More participation in national/international grant-funded programs or consortiums would enhance the scale and visibility of his research.

  4. Focused Research Niche
    Narrowing focus slightly (e.g., prioritizing tumor immunology or exosome-based therapies) could help build a globally recognized brand in a specialized field.

🎓 Education:

Dr. Atashzar completed his undergraduate and master’s studies in Immunology at Shiraz University of Medical Sciences (SUMS), Shiraz, Iran. Building on his foundational expertise, he pursued his PhD in Immunology at Shahid Beheshti University of Medical Sciences, Tehran. His doctoral thesis—“Investigation of the Effects of B16F10 Derived Exosomes Enriched with miRNA-211 in Induction of Antitumor Response in the Mouse Model of Melanoma”—reflected his early interest in cancer immunotherapy and translational research. Throughout his academic journey, Dr. Atashzar displayed a strong inclination toward exploring novel immune pathways and cell-based therapies. His formal education has laid a robust foundation for his ongoing work in immunological sciences, particularly in relation to tumor microenvironment, cytokine profiling, exosomes, and vaccine innovation. He has also undertaken continuous learning through collaborations and international scientific conferences, allowing him to integrate cutting-edge methodologies into his research and teaching repertoire.

🧪 Professional Experience:

Dr. Mohammad Reza Atashzar currently serves as an Assistant Professor of Immunology at Fasa University of Medical Sciences, with additional teaching responsibilities at Larestan University of Medical Sciences. He has accumulated over a decade of experience in academic instruction and biomedical research. His research portfolio includes multiple funded projects, notably in cancer immunology, cytokine regulation, diabetes-related immune responses, and exosome-based therapeutics. Dr. Atashzar has worked closely with international teams in Germany, Finland, and the UK, facilitating interdisciplinary approaches and innovations in clinical immunology. He is an editorial board member for reputed journals such as The International Journal of Neuroscience and Journal of International Medical Research. In parallel, he actively contributes to conference presentations worldwide, covering topics from cancer stem cells to immune biomarkers. His hands-on laboratory experience, combined with a global research network, enables him to lead and mentor in advanced areas like CAR-T cell therapy and personalized immunotherapy.

🧬 Research Focus:

Dr. Atashzar’s research is centered on tumor immunology, exosome-based therapies, cancer stem cells, CAR-T cell technology, cytokine profiling, and immunopharmacology. He has a keen interest in how immune cells—particularly T cells, NK cells, and regulatory B cells—can be harnessed for cancer therapy. His notable projects have explored the immunomodulatory effects of miRNA-enriched exosomes, the role of TLR4 polymorphisms in diabetes, and cytokine alterations in addiction and radiation-exposed individuals. He is also pioneering in translational research areas such as vaccine design, radiogenomics, and bio-immune device development. Dr. Atashzar integrates bioinformatics and machine learning for predictive modeling, evident in his contributions to COVID-19 prognostic modeling using CT radiomics. His work is driven by the goal of personalized immunotherapy and the identification of novel biomarkers for cancer progression and immune regulation. Through interdisciplinary collaborations, he aims to bridge the gap between immunological research and clinical application.

📚 Publications Top Notes:

  1. 🧬 Cancer stem cells: A review from origin to therapeutic implicationsJournal of Cellular Physiology

  2. 🧪 Tumor‐Derived Exosomes Enriched by miRNA‐211a Promote Antitumor Immune Response in B16F10 Tumor‐Bearing MiceAPMIS

  3. 🔬 The effects of tumor-derived exosomes enriched with miRNA-211a on B16F10 cellsContemporary Oncology

  4. 💉 The effects of type 2 diabetes mellitus on organ metabolism and the immune systemFrontiers in Immunology

  5. 🧠 Pyrin and hematopoietic interferon-inducible nuclear protein domain proteins: innate immune sensors for cytosolic and nuclear DNACritical Reviews in Immunology

  6. 🧪 Reduced levels of T-helper 17-associated cytokines in serum of breast cancer patientsCentral European Journal of Immunology

  7. 🧫 The Role of IL‐6, IL‐10 and CRP in Gastrointestinal CancersCell Biology International

  8. 🌍 The global burden of adolescent and young adult cancer in 2019The Lancet Oncology

  9. 🖥️ COVID-19 prognostic modeling using CT radiomic features and ML algorithmsComputers in Biology and Medicine

  10. 🌡️ Mesenchymal stromal cells in bone marrow niche of multiple myelomaCancer Cell International

📌 Conclusion:

Dr. Mohammad Reza Atashzar is highly suitable for the Best Researcher Award. His body of work reflects a deep commitment to scientific advancement in cancer immunology, immunotherapy, and bio-innovation. He combines strong academic output with international engagement, cross-disciplinary impact, and teaching contributions. With growing influence in both research and translational domains, Dr. Atashzar is poised to further elevate biomedical research in Iran and globally.

ALINE TAKEJIMA | Tissue engineering | Women Researcher Award

Dr. ALINE TAKEJIMA | tissue engineering | Women Researcher Award

Dr. ALINE TAKEJIMA, pontificia universidade catolica do parana, Brazil

Dr. Aline Luri Takejima is a physician-scientist from Brazil, specializing in regenerative medicine and wound healing. She holds an MD and a PhD in Health Sciences from the Pontifical Catholic University of Paraná (PUCPR), where she currently conducts postdoctoral research. With a focus on biological therapies involving the amniotic membrane, Wharton’s jelly, and mononuclear stem cells, Dr. Takejima has published in multiple high-impact scientific journals. Her research aims to develop novel regenerative strategies to treat complex wounds and enhance tissue repair. As an active member of PUCPR’s Wound Healing Research Group and the Brazilian Society of Plastic Surgery, she combines scientific rigor with clinical insight to bridge bench-to-bedside innovation. Her academic contributions are guided by a translational approach, offering promising avenues for future clinical applications in tissue engineering.

Publication Profile: 

Orcid

✅ Strengths for the Award:

  1. Focused Research Excellence:
    Dr. Takejima’s work on biological scaffolds and stem cells in wound healing is both innovative and clinically relevant. Her studies using amniotic membrane, Wharton’s jelly, and bone marrow mononuclear cells show promising regenerative outcomes in preclinical models.

  2. Research Productivity:
    With 9 peer-reviewed journal articles in high-quality platforms (e.g., Biomedicines, Tissue Barriers, Annals of Biomedical Engineering), she demonstrates consistent academic output in her field.

  3. Translational Impact:
    Her research bridges basic science and clinical practice, aiming to provide regenerative solutions for patients with chronic wounds and cardiac damage.

  4. Collaborative Engagement:
    Active participation in a multidisciplinary wound healing research group, contributing to cross-functional scientific advancements.

  5. Recognition Potential:
    As a young, emerging woman researcher in biomedical sciences, she stands as a role model for future female scientists in Latin America and beyond.

🔧 Areas for Improvement:

  1. Intellectual Property & Innovation:
    No patents filed yet; transitioning her research into patentable therapies or commercial applications would increase its societal and economic impact.

  2. Leadership Roles:
    While active in research, taking on editorial or scientific leadership positions would enhance her academic visibility and influence.

  3. Internationalization:
    She would benefit from developing international collaborations or fellowships to diversify her research scope and increase global reach.

  4. Industry Engagement:
    Engaging in consultancy or biotech partnerships can further the translational impact of her regenerative strategies.

🎓 Education:

Dr. Takejima’s educational journey began with a Doctor of Medicine (MD) degree from the Pontifical Catholic University of Paraná (PUCPR), Brazil. Her passion for research led her to pursue a Doctorate (PhD) in Health Sciences/Medicine, also at PUCPR. Her doctoral thesis focused on the use of biologically active materials such as the amniotic membrane and stem cells to enhance wound healing. Throughout her academic training, she demonstrated a strong commitment to translational medicine by integrating basic science with clinical practice. During her PhD, she engaged in experimental models involving stem cell therapy and tissue engineering, which laid the groundwork for her current postdoctoral research. Her educational path reflects both depth and specialization in the biomedical sciences, particularly in regenerative medicine and cellular therapies.

💼 Experience:

Dr. Aline Takejima has over a decade of experience in medical and scientific fields, balancing her role as a physician with that of a postdoctoral researcher. Her clinical background informs her research, particularly in areas of wound healing and regenerative medicine. At PUCPR, she contributes to the Wound Healing Research Group, where she is involved in designing and conducting animal model studies to test the effects of biomaterials and stem cells. Her multidisciplinary research integrates immunology, histopathology, and molecular biology. With nine peer-reviewed publications and participation in collaborative research, she has become a respected contributor to the field. Though early in her research career, her trajectory shows a steady rise, marked by evidence-based outcomes and a commitment to innovation. Her goal is to bridge clinical challenges with regenerative solutions that can be implemented in real-world medical practice.

🔬 Research Focus:

Dr. Takejima’s research focuses on regenerative strategies for wound healing, utilizing biomaterials and stem cells. Her work primarily explores the application of amniotic membrane, Wharton’s jelly, and bone marrow-derived mononuclear stem cells in treating complex or chronic skin wounds. Using experimental models in rats and rabbits, she evaluates histological recovery, inflammation modulation, and tissue regeneration. A significant aspect of her research is understanding how these materials promote healing through paracrine effects rather than direct integration, offering a safer and scalable pathway to clinical application. Additionally, her work extends to cardiac and tracheal tissue repair, emphasizing the versatility of these regenerative approaches. The translational nature of her research bridges laboratory discoveries with potential bedside applications, positioning her at the forefront of cellular therapy and biomaterials science.

📚 Publications Top Notes:

  1. 🧠 Wharton’s Jelly Bioscaffolds Improve Cardiac Repair with Bone Marrow Mononuclear Stem Cells in RatsJournal of Functional Biomaterials, 2025

  2. 🧫 The effects of decellularized amniotic membrane and Wharton’s jelly on the healing of experimental skin wounds in ratsTissue Barriers, 2025

  3. ❤️ Bone-marrow mononuclear cells and acellular human amniotic membrane improve global cardiac function…Anais da Academia Brasileira de Ciências, 2024

  4. 🫁 Tracheal regeneration with acellular human amniotic membrane and 15d-PGJ2 nanoparticles in rabbitsAnais da Academia Brasileira de Ciências, 2023

  5. 🧬 Acellular Biomaterials + Autologous Stem Cells Improve Wound Healing via Paracrine EffectsBiomedicines, 2023

  6. 💉 Decellularized Amniotic Membrane Solubilized with Hyaluronic Acid in Wound HealingAnnals of Biomedical Engineering, 2022

  7. 🧪 Role of Mononuclear Stem Cells and Decellularized Amniotic Membrane in Skin WoundsTissue Barriers, 2022

  8. 🏥 Trauma hepático: epidemiologia de cinco anos…Revista do Colégio Brasileiro de Cirurgiões, 2008

🧾 Conclusion:

Dr. Aline Luri Takejima is an outstanding candidate for the Women Researcher Award. Her academic profile demonstrates a strong foundation in regenerative medicine with significant contributions to wound healing research. Her commitment to applying biological therapies in clinical contexts shows both depth and innovation. As a woman scientist in a competitive field, she exemplifies leadership, dedication, and potential. With further growth in global engagement and innovation strategy, Dr. Takejima is poised to become a future leader in regenerative biomedical research.

Hongliang Xin | Tissue Engineering Regeneration | Best Researcher Award

Prof. Dr. Hongliang Xin | Tissue Engineering Regeneration | Best Researcher Award

Prof. Dr. Hongliang Xin, Nanjing Medical University, China

Professor Hongliang Xin is a distinguished pharmaceutical scientist at Nanjing Medical University, China. After earning his PhD from Fudan University in 2011, he joined Nanjing Medical University and rapidly rose through academic ranks, becoming a full professor by 2020. His international experience includes a research fellowship at North Carolina State University (2015–2016), enriching his global academic outlook. Professor Xin has made significant contributions in drug delivery, particularly for brain disorders and cancer. His work on biomimetic nanoparticles and dual-targeting systems has been widely recognized, with several of his publications cited hundreds of times. He is a recipient of the Jiangsu Outstanding Research Award and has contributed to translational science through interdisciplinary collaboration. Committed to innovation in intelligent drug delivery, Professor Xin continues to push boundaries in nanomedicine. His dedication and impactful research make him a strong candidate for the Best Researcher Award.

Publication Profile: 

Google Scholar

✅ Strengths for the Award:

  1. Innovative Research in Drug Delivery
    Prof. Xin has led pioneering work in cellular biomimetic drug delivery systems and brain-targeted therapies, particularly utilizing Angiopep-conjugated and ROS-responsive nanoparticles. His research shows deep innovation in crossing the blood-brain barrier — a major challenge in neuroscience and oncology.

  2. Strong Publication Record
    He has authored multiple high-impact publications in top-tier journals such as Biomaterials, ACS Nano, and Advanced Materials. Several of these works have citations exceeding 300–400, indicating significant influence in the scientific community.

  3. International Research Exposure
    His experience as a visiting scholar at North Carolina State University reflects a global approach to science, enhancing both the breadth and depth of his research collaborations.

  4. Consistent Career Growth
    From lecturer to professor within a decade, Prof. Xin’s steady academic rise reflects both merit and dedication.

  5. Recognition and Awards
    Recipient of the Jiangsu Outstanding Research Award, validating his contributions at the provincial and national level.

⚙️ Areas for Improvement:

  1. Clinical Translation
    While preclinical research is robust, moving towards clinical trials or commercial partnerships would greatly strengthen the translational impact of his work.

  2. Leadership in International Consortia
    Increased participation or leadership in global research initiatives, conferences, or consortia could further elevate his visibility and impact internationally.

  3. Cross-Disciplinary Outreach
    Expanding collaborations into neuropsychology, regenerative medicine, or pharmaceutical industry applications could broaden the application of his delivery systems.

🎓 Education:

Hongliang Xin completed his doctoral studies in Pharmacy at Fudan University in 2011, one of China’s most prestigious universities. His academic journey was grounded in pharmaceutical sciences, focusing on drug delivery systems and nanotechnology-based therapies. During his PhD, he laid the foundation for his future research in targeted therapy and biomimetic materials. Post-PhD, he expanded his academic training internationally as a visiting scholar at North Carolina State University in the United States (2015–2016). This exposure to global research trends and interdisciplinary approaches further honed his expertise. The integration of chemical engineering, pharmacology, and nanotechnology into his educational training has allowed him to develop innovative and effective therapeutic strategies for brain-targeted drug delivery. His education has not only equipped him with strong technical skills but also with a visionary approach to translational medicine.

🧪 Experience:

Dr. Hongliang Xin began his academic career as a lecturer at Nanjing Medical University’s School of Pharmacy in 2011. He was promoted to Associate Professor in 2015 and became a Full Professor in 2020. Over the years, he has built a robust research program in nanomedicine and drug delivery, leading multiple funded projects and mentoring graduate students. His one-year tenure as a visiting scholar at North Carolina State University provided him international collaborative opportunities, boosting his cross-disciplinary competence. Professor Xin has published extensively in high-impact journals such as Biomaterials, ACS Nano, and Advanced Materials. He is also a recognized leader in translational drug delivery platforms, specifically for brain diseases and cancer. His extensive teaching, grant acquisition, and collaborative research background reflect both academic maturity and innovation. His professional journey exemplifies excellence, persistence, and a global perspective on healthcare research.

🔬 Research Focus:

Professor Hongliang Xin’s research centers on cellular biomimetic drug delivery systems and intelligent therapeutic strategies for brain diseases such as glioblastoma and ischemic stroke. His work integrates polymer chemistry, pharmacokinetics, and molecular targeting to design nanoparticles that can cross the blood-brain barrier with precision. A key innovation in his research is the use of Angiopep-conjugated polymers and ROS-responsive carriers to ensure site-specific and safe drug delivery. His dual-targeting PEG-PCL nanoparticle system has shown remarkable results in preclinical models of brain cancer, while his transcutaneous immunotherapy approach enhances anti-tumor immunity. Professor Xin’s focus also extends to thrombolytic delivery systems, neuroprotectants, and engineered nano-platelets for hematologic malignancies. With over a decade of focused work, his lab continues to address clinical challenges in oncology and neurology, aiming to translate nanoscale innovations into real-world therapeutics.

📚 Publications Top Notes:

  1. 🧠💊 Angiopep-conjugated PEG-PCL nanoparticles as dual-targeting system for brain glioma

  2. 🧬🛡 Anti-glioblastoma efficacy of paclitaxel-loaded Angiopep-conjugated PEG-PCL nanoparticles

  3. 💉🧫 Synergistic transcutaneous immunotherapy for checkpoint inhibitor delivery and tumor response

  4. 🧠🎯 2-deoxy-D-glucose functionalized PEG-PTMC nanoparticles for glioma targeting

  5. 🧠⚡ Boronic ester-dextran polymer nanoparticles responsive to ROS for stroke therapy

  6. 🧫🩸 Nano-platelets for enhanced treatment of multiple myeloma and thrombus

  7. 🧠🧬 Site-specific delivery of thrombolytics and neuroprotectants for ischemic stroke

  8. 🧠🧪 Brain targeting mechanism of Angiopep-conjugated PEG-PCL nanoparticles

  9. 🧠💉 Dual-targeted nanocarrier for treatment of brain ischemic stroke

  10. 💊🧠 Integrin-mediated PEG-PTMC nanoparticles for solid tumor penetration and paclitaxel delivery

🧾 Conclusion:

Professor Hongliang Xin is a highly qualified and impactful researcher whose contributions in intelligent, targeted drug delivery—especially for brain diseases—are both scientifically innovative and socially relevant. His work bridges critical gaps in nanomedicine and therapeutic targeting, and his publications are widely cited, reflecting broad recognition. With strategic focus on clinical translation and deeper global engagement, his already excellent profile could reach even greater heights.

Salvatore Chirumbolo | Cellular Stress Response | Innovative Research Award

Dr. Salvatore Chirumbolo | Cellular Stress Response | Innovative Research Award

Dr. Salvatore Chirumbolo, Università di Verona, Italy

Dr. Salvatore Chirumbolo is a distinguished Clinical Biochemist and Senior Researcher at the University of Verona, Department of Engineering for Innovation Medicine. He has made pioneering contributions in oxidative stress, immunopharmacology, systems biology, and ozone therapy. Author of over 400 scientific papers and several books, he is among Italy’s most cited biomedical scientists with an h-index of 46. His innovative work includes developing models for chaotic modulation in redox biology and proposing the concept of Shannon dissipation as a thermodynamic foundation for life. Dr. Chirumbolo has extensive editorial experience, serving on the boards of renowned journals including Scientific Reports, International Immunopharmacology, and Molecules. He actively collaborates with international institutions across Europe and promotes integrative, transdisciplinary biomedical approaches. His dedication to biophysical complexity and system-based innovation continues to influence translational medicine, making him an ideal nominee for the Research for Innovative Research Award.

Publication Profile:

Google Scholar

Scopus

✅ Strengths for the Award:

  1. Innovative Scientific Contributions:
    Dr. Chirumbolo’s concept of Shannon dissipation as the thermodynamic foundation of life represents a paradigm shift in theoretical biology. His model bridges information theory with biogenesis, advancing the frontiers of systems immunology and biological epistemology.

  2. Translational Research in Ozone Therapy:
    His chaotic modulation model for medical ozone effects introduces a systems-level interpretation of therapeutic mechanisms, with significant implications for redox biology, regenerative medicine, and inflammation management.

  3. Prolific Academic Output:
    With over 400 publications indexed in Scopus and Google Scholar, and an h-index of 46, Dr. Chirumbolo demonstrates sustained academic productivity, peer recognition, and impact in biomedical sciences.

  4. Editorial and Leadership Roles:
    He is actively involved with high-impact journals including Scientific Reports (Nature portfolio), International Immunopharmacology, and Molecules, contributing to global scientific discourse.

  5. Global Collaborations:
    His affiliations with institutions in Norway, Ukraine, Romania, Poland, and Italy reflect his commitment to cross-border scientific exchange and integrative research efforts.

🔧 Areas for Improvement:

  1. Patent and Industry Translation:
    Despite deep theoretical and experimental knowledge, Dr. Chirumbolo’s portfolio currently lacks patents or industrial consultancy projects. Advancing translational aspects of his models into commercial or clinical applications would enhance real-world impact.

  2. Public Communication and Outreach:
    While academically prolific, wider dissemination of his findings to non-specialist or policy-making audiences could increase societal relevance and interdisciplinary uptake.

🎓 Education:

Dr. Chirumbolo earned his Medical Specialization in Biochemical Chemistry in 1995, marking the beginning of his journey in biomedical sciences. His academic roots are grounded in clinical biochemistry, molecular biology, and translational medicine. He trained in Italy’s National Health System, where he directed various molecular biology laboratories, gaining firsthand experience in diagnostic innovation and experimental biochemistry. With a strong foundation in cellular and molecular biology, his educational path laid the groundwork for his systems-level understanding of biological complexity. His commitment to continuous learning is evident in his interdisciplinary research spanning immunology, redox biology, information theory, and ozone therapy. He is actively engaged in scientific discourse through editorial appointments and international conferences, nurturing the next generation of systems biologists and medical scientists. His academic lineage blends traditional biochemical education with pioneering insights into biological epistemology and complex systems science.

🧪 Experience:

Dr. Chirumbolo has over three decades of professional experience in biochemistry, molecular biology, and translational research. Starting in Italy’s National Health System, he directed molecular labs focusing on clinical diagnostics and immunological assays. He later transitioned to academia, becoming a Senior Researcher at the University of Verona. He has led major research initiatives involving oxidative stress, basophil biology, and the use of phytochemicals in chronic diseases. As an editor for journals like Scientific Reports, International Immunopharmacology, and Molecules, he has shaped international scientific dialogue. His collaborations span Italy, Norway, Ukraine, Romania, and Poland, involving diverse domains such as chemical biology and clinical immunology. He also contributes to bioinformatic modeling of redox systems and life origin theories. With over 400 indexed publications, Dr. Chirumbolo’s multidisciplinary expertise bridges clinical and theoretical biosciences, driving innovative solutions in modern medicine.

🔬 Research Focus:

Dr. Chirumbolo’s research focuses on biomedical systems, oxidative stress, and the thermodynamic foundations of life. He developed the novel concept of Shannon dissipation, linking informational entropy to the emergence of biological life, aligning with thinkers like Varela and Maturana. His work in ozone therapy led to the formulation of chaotic modulation models that explain its redox-based medical efficacy. He also investigates bioinformatic modeling, basophil signaling, phytochemical impacts, and nutraceutical interventions in chronic inflammation, allergy, and metabolic disorders. His models propose mechanistic insights into cell signaling and antioxidant networks, enhancing therapeutic targeting. Recent contributions include exploring the microvascular effects of SARS-CoV-2, the interface of redox dynamics and cellular adaptation, and ozone’s systemic regulatory properties. Through extensive collaborations, he integrates cellular, chemical, and systems-level research to push the boundaries of personalized and integrative medicine.

📚 Publications Top Notes:

  • 🧪 Ozone therapy addresses neuropathic pain in ulcerous wounds

  • 🍊 Something more about the role of flavonoids in aging

  • 🩸 Prolonged alterations in red blood cell rheology following mild SARS-CoV-2 infection: Implications for microvascular health

  • 💉 Intravenous glutathione should not be mismatched with ozone as an antioxidant therapy

  • 🌬️ Sonic transdermal transfer of ozone and its use in oxygen-ozone therapy. Wheat and chaff

  • 🧬 Effect of SARS-CoV2 S protein on red blood cells parameters. Some comments

  • ⚠️ Adverse effects following some practices of ozone therapy for disc herniation. Critical comments

  • 🧠 Post-infective myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and post-COVID as two puzzling faces of the same medal

  • 🦴 Synovial Fluid as a Crucial Component of the Joint Microenvironment in Rheumatoid Arthritis

  • ❤️ Aetiology and clinical manifestations of patients with non-dilated left ventricular cardiomyopathy. Some comments

🧾 Conclusion:

Dr. Salvatore Chirumbolo is highly suited for the Research for Innovative Research Award. His work exemplifies pioneering thought, multidisciplinary integration, and scientific originality. From foundational biological theory to clinically relevant applications like ozone therapy and oxidative stress modulation, his contributions address both the “why” and “how” of living systems. His influence is evident in his citation record, editorial appointments, and leadership in cutting-edge biomedical modeling.