Luminita Paraoan | Cancer Cell Biology | Best Researcher Award

Prof. Dr. Luminita Paraoan | Cancer Cell Biology | Best Researcher Award

Manchester Metropolitan University | United Kingdom

Professor Luminita Paraoan is a leading molecular and ocular cell biologist whose research focuses on the molecular mechanisms underlying retinal pigment epithelium (RPE) function, degeneration, and age-related macular degeneration (AMD). Her pioneering work integrates omics-based analyses, molecular genetics, and cell biology to uncover how cellular stress responses, proteostasis, and intercellular communication contribute to retinal aging and disease. Paraoan has made significant discoveries on endoplasmic reticulum (ER) stress pathways, particularly the PERK/EIF2AK3 axis, and the regulation of apoptosis, oxidative stress, and autophagy in RPE cells. Her studies have also revealed novel insights into p53/p63 effector PERP, Cystatin C, and visual cycle gene regulation in aging and disease contexts. Through collaborative research, she has explored stem cell protection mechanisms, PI3K/AKT signaling inhibition, and multi-omic signatures of aging across cancers and ocular tissues. Supported by over £4 million in external funding, her work has advanced understanding of molecular targets for retinal and neurodegenerative diseases. Professor Paraoan leads the Ocular Molecular Biology and Mechanisms of Disease Group, mentoring numerous postdoctoral and doctoral researchers internationally, and continues to shape the field of vision science and molecular ophthalmology.

Profiles: Google Scholar | Scopus | Orcid

Featured Publications:

Suwanmanee, G., Kheolamai, P., Tantrawatpan, C., Grimes, D., Matei, I. V., Paraoan, L., & Manochantr, S. (2025). Fucoxanthin protects placenta-derived human mesenchymal stem cells against oxidative stress-induced apoptosis by modulating genes involved in DNA damage repair, ER stress response, and p53-induced apoptosis. Stem Cell Research & Therapy, 16(1), 497.

Jantalika, T., Manochantr, S., Kheolamai, P., Tantikanlayaporn, D., Pinlaor, S., Saijuntha, W., Paraoan, L., & Tantrawatpan, C. (2025). Human chorion and placental mesenchymal stem cells conditioned media suppress cell migration and invasion by inhibiting the PI3K/AKT pathway in cholangiocarcinoma. Scientific Reports, 15(1), 31472.

Matei, I. V., & Paraoan, L. (2024). Aging retinal pigmented epithelium: Omics-based insights into vision decline. Aging (Albany NY), 16(12), 10201–10202.

Carlsson, E., Sharif, U., Supharattanasitthi, W., & Paraoan, L. (2023). Analysis of wild type and variant B cystatin C interactome in retinal pigment epithelium cells reveals variant B. Cells, 12(5), 713.

Dhirachaikulpanich, D., Lagger, C., Chatsirisupachai, K., de Magalhães, J. P., & Paraoan, L. (2022). Intercellular communication analysis of the human retinal pigment epithelial and choroidal cells predicts pathways associated with aging, cellular senescence, and age-related macular degeneration. Frontiers in Aging Neuroscience, 14, 1016293.

Saptarshi, N., Porter, L. F., & Paraoan, L. (2022). PERK/EIF2AK3 integrates endoplasmic reticulum stress-induced apoptosis, oxidative stress, and autophagy responses in immortalised retinal pigment epithelial cells. Scientific Reports, 12(1), 13324.

Farhad Ghorbani | Cancer Cell Biology | Best Researcher Award

Assist. Prof. Dr. Farhad Ghorbani | Cancer Cell Biology | Best Researcher Award

Assist. Prof. Dr. Farhad Ghorbani | Shiraz University of Medical Sciences ,Shiraz,Iran | Iran

Dr. Farhad Ghorbani is an esteemed Assistant Professor of Oral and Maxillofacial Surgery at Shiraz University of Medical Sciences, Iran. With over two decades of clinical and academic experience, he has significantly contributed to the fields of oral pathology, trauma, and surgical interventions. A graduate of Kerman University of Medical Sciences, Dr. Ghorbani later specialized further at Shiraz University. His dedication to advancing clinical knowledge is reflected in over a dozen high-impact peer-reviewed publications, focusing on craniofacial abnormalities, surgical outcomes, and rare oral diseases. He is an active researcher with a Scopus Author ID and ORCID, consistently contributing to scientific journals like BMC Oral Health, Scientific Reports, and Maxillofacial Plastic and Reconstructive Surgery. His multidisciplinary collaborations have led to enhanced diagnostic techniques and patient outcomes. Dr. Ghorbani is recognized for both his innovative research and his commitment to medical education.

Publication Profile: 

Orcid

Google Scholar

Education:

Dr. Ghorbani began his medical journey at Kerman University of Medical Sciences, earning his professional doctorate in dentistry (1992–1998). Following years of clinical practice, he advanced his academic and surgical expertise by joining Shiraz University of Medical Sciences in 2013, where he underwent specialized training in Oral and Maxillofacial Surgery and served as an Assistant Professor during his educational tenure (2013–2018). His academic training focused on maxillofacial pathology, surgical techniques, and interdisciplinary diagnostics. The combination of strong foundational medical education and advanced surgical specialization has equipped him with both the theoretical depth and clinical acumen to lead impactful research. His training underlines a commitment to academic excellence and lifelong learning, which is further reflected in his scholarly contributions. Dr. Ghorbani’s educational background bridges foundational dental sciences with advanced surgical innovation.

Experience:

Since December 2018, Dr. Farhad Ghorbani has held the position of Assistant Professor of Oral and Maxillofacial Surgery at Shiraz University of Medical Sciences, Iran. His career blends clinical practice, research, and teaching. Over the years, he has led numerous studies exploring craniofacial morphology, surgical outcomes, dental trauma, and maxillofacial pathologies. He mentors postgraduate students and collaborates with interdisciplinary teams, enhancing diagnostic accuracy and surgical care. His work in both rural and urban settings has exposed him to a wide spectrum of maxillofacial cases, enriching his clinical insights. He actively contributes to improving surgical protocols and patient care standards. Dr. Ghorbani’s experience also includes academic publishing, peer reviews, and participation in scientific forums. He is recognized for his analytical approach and evidence-based practice. His long-standing affiliation with reputed institutions and research groups underscores his strong leadership in oral surgery and academic scholarship.

Research Focus:

Dr. Ghorbani’s primary research interests lie in oral pathology, craniofacial surgery, dentoalveolar trauma, and radiological diagnostics. His work often combines clinical case reports with retrospective analysis, offering insights into rare presentations such as parathyroid carcinoma-linked jaw tumors, and developmental anomalies like concha bullosa. A hallmark of his research is his ability to identify atypical symptoms and connect them with broader systemic conditions, ensuring early diagnosis and management. He has conducted fractal analysis studies to evaluate bone quality, and he explores patient-centered outcomes, such as satisfaction post-rhinoplasty and the psychological impacts of facial surgery. Additionally, his research evaluates the intersection of dental surgery with systemic health—evident in studies related to auditory changes post-orthognathic surgery or the implications of COVID-19 on dental care. Through evidence-based methods and innovative case analyses, Dr. Ghorbani has positioned himself as a thought leader in interdisciplinary oral and maxillofacial research.

Publications Top Notes:

  1. Brown tumors of both jaws as the initial manifestation of parathyroid carcinoma (BMC Oral Health, 2025)

  2. Distribution and laterality of concha bullosa across cranial skeletal types (Maxillofacial Plastic Surg, 2025)

  3. Calcifying Odontogenic Cyst in Posterior Maxilla: A Case Report (Journal of Dentistry Shiraz, 2025)

  4. Central giant cell granuloma mimicking fibro-osseous lesion and hemangioma (J Med Case Reports, 2024)

  5. Fractal CT analysis of mandibular condyles in class III malocclusion (Scientific Reports, 2023)

  6. Patient dissatisfaction following rhinoplasty: A 10-year Iranian study (Maxillofacial Plastic Surg, 2023)

  7. Correlation between impacted third molar and blood group (Int J of Dentistry, 2021)

  8. Effects of orthognathic surgery on auditory function (Maxillofacial Plastic Surg, 2021)

  9. Evaluation of alveolar fractures in trauma patients in Iran (BMC Oral Health, 2021)

  10. Anxiety in patients undergoing mandibular third molar extraction (J Oral Research & Review, 2020)

Conclusion:

In summary, Dr. Farhad Ghorbani embodies the qualities of a deeply committed, analytically skilled, and academically active oral and maxillofacial surgeon. His research is directly informed by his clinical experience, allowing him to bridge theory and practice effectively. His contributions have enriched the literature on oral pathology, surgical complications, facial aesthetics, and patient psychology following treatment interventions. While there are opportunities to expand the scope and scale of his work through more robust methodologies and international collaboration, his existing portfolio already reflects a high standard of academic and clinical integration. Given his track record, ongoing research productivity, and evident commitment to innovation and education, Dr. Ghorbani is a strong and deserving candidate for the Best Researcher Award. With continued growth in research leadership and expanded global outreach, he is poised to make an even greater impact in the years ahead.

Dukagjin Blakaj | Radiation Oncology | Best Researcher Award

Prof. Dukagjin Blakaj | Radiation Oncology | Best Researcher Award

Prof. Dukagjin Blakaj, The Ohio State University, United States

Dr. Dukagjin M. Blakaj, MD, PhD, is a distinguished physician-scientist and academic leader in radiation oncology, specializing in proton therapy. Currently serving as the Vice Chair of Clinical Operations and holding the prestigious Drs. Malati and Ganesh Potdar Endowed Professorship at The Ohio State University Comprehensive Cancer Center – James Cancer Hospital, he brings visionary leadership in patient-centered oncology care. With dual degrees in medicine and biochemistry, Dr. Blakaj integrates clinical expertise with advanced translational research. He is renowned for developing innovative radiotherapy protocols, advancing artificial intelligence applications in oncology, and mentoring future clinician-scientists. His work significantly influences treatment outcomes for head and neck cancers, including HPV-related oropharyngeal cancer, and is published in top-tier journals. A respected thought leader and collaborative partner, Dr. Blakaj embodies excellence in academic medicine, multidisciplinary team leadership, and compassionate patient care.

Publication Profile: 

Google Scholar

Scopus

Orcid

Education:

Dr. Blakaj’s educational path is both extensive and interdisciplinary. He earned his MD, PhD, and MS in Biochemistry from the Albert Einstein College of Medicine in New York, where he focused on molecular interactions in biological systems. Before that, he completed both a BA in Chemistry and Molecular Biology & Biophysics and an MA in Chemistry from Wesleyan University in Middletown, CT. His doctoral work explored protein-RNA interactions, laying the groundwork for his scientific rigor and precision. This strong biochemical foundation supports his innovative clinical research in radiation oncology and immunotherapy. His education highlights a consistent pattern of academic excellence and intellectual curiosity, equipping him with a rare blend of clinical insight and research acumen that continues to impact cancer treatment paradigms worldwide.

Professional Experience:

Dr. Dukagjin Blakaj is the Vice Chair of Clinical Operations in Radiation Oncology and Drs. Malati and Ganesh Potdar Endowed Professor in Proton Therapy at OSUCCC – James Cancer Hospital. As a senior faculty member, he has led transformative improvements in clinical care, quality assurance, and translational oncology research. His multidisciplinary collaboration extends across surgery, radiology, oncology, and data science, driving innovations such as AI-guided treatment protocols and digital health integration. Dr. Blakaj has also played a critical role in operationalizing proton therapy and implementing personalized cancer therapies. His background spans high-impact clinical trials, program development, and mentorship. The combination of clinical leadership and academic scholarship positions him as a strategic thinker with practical, evidence-driven execution. His commitment to precision medicine and patient-centered care distinguishes him among modern radiation oncologists.

Awards and Honors:

Dr. Blakaj has received numerous accolades that reflect his clinical excellence, research innovation, and service to the academic community. Notably, he was awarded the Drs. Malati and Ganesh Potdar Endowed Professorship in Radiation Oncology – Proton Therapy (effective June 2025), the highest honor granted by Ohio State University. His ABR Volunteer Service Award (July 2025) highlights his contributions to professional standards and education. He was selected for the James Outstanding Physician Peer Award for exemplary leadership, professionalism, and collaboration (August 2024). Additionally, his abstract ranked in the Top 7 of 146 presentations at ACRO, underscoring his research’s national impact. Dr. Blakaj’s consistent recognition across service, research, and teaching is a testament to his dedication, integrity, and influence in the field of oncology.

Research Focus:

Dr. Blakaj’s research is centered on optimizing cancer treatment outcomes through precision radiation therapy, immunotherapy integration, and the application of artificial intelligence in oncology. He focuses primarily on head and neck cancers, with additional emphasis on HPV-associated oropharyngeal carcinoma, FLASH radiotherapy, and treatment response prediction using circulating tumor DNA and inflammatory indices. He co-leads interdisciplinary studies leveraging machine learning, big data, and digital health tools to personalize care and reduce treatment toxicity. His research is both translational and clinically grounded, often influencing national clinical practice guidelines and multi-center trials. As a key contributor to high-impact publications, Dr. Blakaj has established himself as a thought leader in adaptive radiotherapy and survivorship outcomes. His pioneering work in proton therapy protocols and patient-reported outcomes continues to bridge the gap between innovative science and practical oncology care.

Publications Top Notes: 

  1. An integrated ML-based prognostic model in head and neck cancer using inflammatory markers and financial toxicity

  2. Vertebral endplate disruption and compression fracture risk: Expanded radiotherapy analysis

  3. Nasopharyngeal carcinoma in nonendemic regions: Characteristics and treatment outcomes

  4. Emerging paradigms in radiation oncology: Evolution and patient-centric care

  5. FLASH radiotherapy: From in vivo data to clinical translation

  6. Digital health tools in radiation oncology: Development and implementation review

  7. ctDNA as a response marker in HPV-associated oropharyngeal carcinoma: A pilot study

  8. AI, machine learning, and big data in radiation oncology

  9. Predicting cisplatin tolerability in elderly head and neck cancer patients

  10.  Tobacco, marijuana, and alcohol use impact on survival in metastatic head and neck cancer

Conclusion:

Dr. Dukagjin M. Blakaj is a highly qualified, forward-thinking researcher whose body of work exemplifies excellence in translational oncology. He brings together advanced clinical practice, cutting-edge research, and visionary leadership to improve cancer care outcomes and drive future innovations in radiation therapy.

Given his sustained productivity, multidisciplinary leadership, and contributions to patient-centered care models, Dr. Blakaj is a deserving and outstanding nominee for the Best Researcher Award.

Amr Hanbali | Therapeutic use of Cellular therapy in cancer treatment | Best Researcher Award

Assoc. Prof. Dr. Amr Hanbali | Therapeutic use of Cellular therapy in cancer treatment | Best Researcher Award

Assoc. Prof. Dr. Amr Hanbali | King Faisal Specialist Hospital & Research Center | Saudi Arabia

Dr. Amr AlHanbali is a dual-certified Hematology and Oncology consultant with over 18 years of experience in malignant and benign hematological conditions. Based at King Faisal Specialist Hospital & Research Center in Riyadh, Saudi Arabia, he specializes in hematologic malignancies and stem cell transplantation. Dr. AlHanbali previously served as a senior staff physician and Associate Fellowship Program Director at Henry Ford Health System in Detroit, Michigan. Recognized for his academic involvement, he holds teaching appointments at Wayne State University and Alfaisal University. Known for his dedication to clinical mentorship, he has trained numerous medical students, residents, and fellows. He is actively involved in research and is a member of several prestigious medical organizations including the American Society of Hematology and American Society of Clinical Oncology. With expertise ranging from bone marrow procedures to managing complex hematologic disorders, Dr. AlHanbali is a respected leader in the field of hematology and stem cell transplantation.

Publication Profile:

Scopus

Strengths for the Award:

  1. Extensive Research Contribution

    • Over 17 peer-reviewed publications, including impactful case reports, national guidelines, and original research in hematology, oncology, and stem cell transplantation.

    • Active contributor to national guidelines on multiple myeloma, reflecting leadership in shaping national healthcare standards in KSA.

  2. Dual Academic and Clinical Roles

    • Combines academic excellence (as faculty at Wayne State University and Alfaisal University) with hands-on clinical expertise at a premier institution (King Faisal Specialist Hospital & Research Center).

  3. Innovative Focus in Hematology and Transplantation

    • Research into underexplored areas such as hepatitis B reactivation post-rituximab, genetic donor match outcomes, and therapies for AL amyloidosis.

  4. International Exposure and Leadership

    • Experience across the U.S. and Saudi Arabia, influencing programs in both systems.

    • Played a key role in training and selecting future hematology-oncology fellows in the U.S.

  5. Mentorship and Capacity Building

    • Mentored numerous trainees, enhancing research culture among younger clinicians.

Areas for Improvement:

  1. Higher Impact Publications Needed

    • While the volume and variety of research are commendable, more publications in top-tier journals (NEJM, Lancet, Blood, JCO) could boost citation impact and visibility.

  2. Research Grants and Collaborative Trials

    • Pursuing multicenter studies, international collaborations, or industry-sponsored clinical trials would further elevate his profile and expand research funding sources.

  3. Technological Innovation/Patents

    • Exploring biotech innovation, AI in diagnostics, or cellular therapy patents could position him among the top medical innovators.

Education:

Dr. Amr AlHanbali completed his Bachelor of Medicine and Surgery from the University of Jordan in 1999. He pursued medical training in the United States, starting with an internal medicine residency (2001–2004) at Henry Ford Health System, Detroit. He continued his specialization with a fellowship in Hematology and Oncology (2004–2007) at the same institution. During his training, he also undertook elective rotations in Pediatric Cardiology and Gastroenterology at the University of Texas Medical Branch, Galveston, further enriching his academic exposure. He is certified by the American Board of Internal Medicine in Internal Medicine (2004), Hematology (2007), and Oncology (2007). Dr. AlHanbali holds academic titles as a Clinical Assistant Professor at Wayne State University, Detroit, and Adjunct Associate Professor at Alfaisal University, Riyadh. His educational background reflects a strong foundation in internal medicine, with a deep focus on hematology and oncology, further supported by teaching and research excellence.

Experience:

Dr. AlHanbali’s clinical career spans over 18 years, currently serving as Hematology and Stem Cell Transplant Consultant at King Faisal Specialist Hospital & Research Center in Riyadh since 2013. Prior to this, he held multiple leadership roles at Henry Ford Health System, Detroit, including Senior Staff Physician and Associate Fellowship Program Director (2007–2013). His medical expertise covers the diagnosis and treatment of a wide range of hematologic malignancies such as leukemia, lymphoma, multiple myeloma, and myeloproliferative disorders. Dr. AlHanbali also has extensive experience in stem cell transplantation, intrathecal chemotherapy, and bone marrow biopsy. He has been instrumental in resident selection and curriculum development for fellowship programs in hematology and oncology. His work bridges clinical excellence with academic mentorship, guiding numerous trainees and junior physicians. In addition to patient care, he is involved in clinical guideline development and research, particularly in the field of multiple myeloma and transplant outcomes.

Research Focus:

Dr. Amr AlHanbali’s research is centered on hematologic malignancies, particularly multiple myeloma, lymphoma, leukemia, and stem cell transplantation. His work explores novel therapeutic approaches, transplant outcomes, disease progression, and treatment-related complications. He has contributed significantly to research on hepatitis B reactivation, chemotherapy-induced toxicities, and the protective role of comorbidities like diabetes in cancer metastasis. As an active member of the Saudi Myeloma Working Group, he has co-authored national guidelines for both newly diagnosed and relapsed/refractory multiple myeloma. His studies also examine health disparities in cancer care, including outcomes among African American populations and the impact of familial genetics in donor matches. With over a dozen peer-reviewed publications and case reports in high-impact journals, Dr. AlHanbali continues to push forward understanding in clinical hematology and oncology. He combines bedside insights with academic rigor to shape evidence-based practice and improve treatment outcomes in cancer and transplant medicine.

Publications Top Notes:

  1.  Mediastinal Hematoma With SVC Syndrome From A Central Venous Catheter Insertion – CHEST, 2003

  2.  Diabetes Has Protective Effect Against Metastasis in Non-Small Cell Lung Cancer – Arch Intern Med, 2007

  3.  Delayed Hepatitis B Viral Replication Post-Rituximab & Fludarabine in Waldenstrom Macroglobulinemia – Am J Hematol, 2007

  4.  Acute Pancreatitis Induced by Adult Precursor B-cell ALL – South Med J, 2007

  5.  Hypersensitivity Reaction of Mylotarg with Platelet Transfusion – Am J Health Syst Pharm, 2007

  6.  Incidence of Hepatitis B Reactivation after Rituximab Therapy – Am J Hematol, 2009

  7. Outcomes After Auto-SCT in African Americans with Multiple Myeloma – Bone Marrow Transplant, 2009

  8.  HER-2 Status May Change in Recurrent Breast Cancer – Cancer Research, 2009

  9.  Compartment Syndrome as Presentation of Chronic Myelogenous Leukemia – J Gen Intern Med, 2010

  10.  Use of Insulin and its Effect on Survival in NSCLC – J Clin Oncol, 2009

Conclusion:

Dr. Amr AlHanbali demonstrates a stellar blend of clinical expertise, research productivity, academic mentorship, and leadership in hematology and oncology. His research contributions have practical implications in areas such as multiple myeloma, leukemia, transplant immunology, and chemotherapy safety.

He is highly deserving of recognition and stands out as a top contender for a Best Researcher Award, particularly in the categories of clinical research excellence, translational hematology, and medical education integration with research.