Hongliang Xin | Tissue Engineering Regeneration | Best Researcher Award

Published on by Cell Biologist

Prof. Dr. Hongliang Xin | Tissue Engineering Regeneration | Best Researcher Award

Prof. Dr. Hongliang Xin, Nanjing Medical University, China

Professor Hongliang Xin is a distinguished pharmaceutical scientist at Nanjing Medical University, China. After earning his PhD from Fudan University in 2011, he joined Nanjing Medical University and rapidly rose through academic ranks, becoming a full professor by 2020. His international experience includes a research fellowship at North Carolina State University (2015–2016), enriching his global academic outlook. Professor Xin has made significant contributions in drug delivery, particularly for brain disorders and cancer. His work on biomimetic nanoparticles and dual-targeting systems has been widely recognized, with several of his publications cited hundreds of times. He is a recipient of the Jiangsu Outstanding Research Award and has contributed to translational science through interdisciplinary collaboration. Committed to innovation in intelligent drug delivery, Professor Xin continues to push boundaries in nanomedicine. His dedication and impactful research make him a strong candidate for the Best Researcher Award.

Publication Profile: 

Google Scholar

✅ Strengths for the Award:

  1. Innovative Research in Drug Delivery
    Prof. Xin has led pioneering work in cellular biomimetic drug delivery systems and brain-targeted therapies, particularly utilizing Angiopep-conjugated and ROS-responsive nanoparticles. His research shows deep innovation in crossing the blood-brain barrier — a major challenge in neuroscience and oncology.

  2. Strong Publication Record
    He has authored multiple high-impact publications in top-tier journals such as Biomaterials, ACS Nano, and Advanced Materials. Several of these works have citations exceeding 300–400, indicating significant influence in the scientific community.

  3. International Research Exposure
    His experience as a visiting scholar at North Carolina State University reflects a global approach to science, enhancing both the breadth and depth of his research collaborations.

  4. Consistent Career Growth
    From lecturer to professor within a decade, Prof. Xin’s steady academic rise reflects both merit and dedication.

  5. Recognition and Awards
    Recipient of the Jiangsu Outstanding Research Award, validating his contributions at the provincial and national level.

⚙️ Areas for Improvement:

  1. Clinical Translation
    While preclinical research is robust, moving towards clinical trials or commercial partnerships would greatly strengthen the translational impact of his work.

  2. Leadership in International Consortia
    Increased participation or leadership in global research initiatives, conferences, or consortia could further elevate his visibility and impact internationally.

  3. Cross-Disciplinary Outreach
    Expanding collaborations into neuropsychology, regenerative medicine, or pharmaceutical industry applications could broaden the application of his delivery systems.

🎓 Education:

Hongliang Xin completed his doctoral studies in Pharmacy at Fudan University in 2011, one of China’s most prestigious universities. His academic journey was grounded in pharmaceutical sciences, focusing on drug delivery systems and nanotechnology-based therapies. During his PhD, he laid the foundation for his future research in targeted therapy and biomimetic materials. Post-PhD, he expanded his academic training internationally as a visiting scholar at North Carolina State University in the United States (2015–2016). This exposure to global research trends and interdisciplinary approaches further honed his expertise. The integration of chemical engineering, pharmacology, and nanotechnology into his educational training has allowed him to develop innovative and effective therapeutic strategies for brain-targeted drug delivery. His education has not only equipped him with strong technical skills but also with a visionary approach to translational medicine.

🧪 Experience:

Dr. Hongliang Xin began his academic career as a lecturer at Nanjing Medical University’s School of Pharmacy in 2011. He was promoted to Associate Professor in 2015 and became a Full Professor in 2020. Over the years, he has built a robust research program in nanomedicine and drug delivery, leading multiple funded projects and mentoring graduate students. His one-year tenure as a visiting scholar at North Carolina State University provided him international collaborative opportunities, boosting his cross-disciplinary competence. Professor Xin has published extensively in high-impact journals such as Biomaterials, ACS Nano, and Advanced Materials. He is also a recognized leader in translational drug delivery platforms, specifically for brain diseases and cancer. His extensive teaching, grant acquisition, and collaborative research background reflect both academic maturity and innovation. His professional journey exemplifies excellence, persistence, and a global perspective on healthcare research.

🔬 Research Focus:

Professor Hongliang Xin’s research centers on cellular biomimetic drug delivery systems and intelligent therapeutic strategies for brain diseases such as glioblastoma and ischemic stroke. His work integrates polymer chemistry, pharmacokinetics, and molecular targeting to design nanoparticles that can cross the blood-brain barrier with precision. A key innovation in his research is the use of Angiopep-conjugated polymers and ROS-responsive carriers to ensure site-specific and safe drug delivery. His dual-targeting PEG-PCL nanoparticle system has shown remarkable results in preclinical models of brain cancer, while his transcutaneous immunotherapy approach enhances anti-tumor immunity. Professor Xin’s focus also extends to thrombolytic delivery systems, neuroprotectants, and engineered nano-platelets for hematologic malignancies. With over a decade of focused work, his lab continues to address clinical challenges in oncology and neurology, aiming to translate nanoscale innovations into real-world therapeutics.

📚 Publications Top Notes:

  1. 🧠💊 Angiopep-conjugated PEG-PCL nanoparticles as dual-targeting system for brain glioma

  2. 🧬🛡 Anti-glioblastoma efficacy of paclitaxel-loaded Angiopep-conjugated PEG-PCL nanoparticles

  3. 💉🧫 Synergistic transcutaneous immunotherapy for checkpoint inhibitor delivery and tumor response

  4. 🧠🎯 2-deoxy-D-glucose functionalized PEG-PTMC nanoparticles for glioma targeting

  5. 🧠⚡ Boronic ester-dextran polymer nanoparticles responsive to ROS for stroke therapy

  6. 🧫🩸 Nano-platelets for enhanced treatment of multiple myeloma and thrombus

  7. 🧠🧬 Site-specific delivery of thrombolytics and neuroprotectants for ischemic stroke

  8. 🧠🧪 Brain targeting mechanism of Angiopep-conjugated PEG-PCL nanoparticles

  9. 🧠💉 Dual-targeted nanocarrier for treatment of brain ischemic stroke

  10. 💊🧠 Integrin-mediated PEG-PTMC nanoparticles for solid tumor penetration and paclitaxel delivery

🧾 Conclusion:

Professor Hongliang Xin is a highly qualified and impactful researcher whose contributions in intelligent, targeted drug delivery—especially for brain diseases—are both scientifically innovative and socially relevant. His work bridges critical gaps in nanomedicine and therapeutic targeting, and his publications are widely cited, reflecting broad recognition. With strategic focus on clinical translation and deeper global engagement, his already excellent profile could reach even greater heights.

Xin Li | Biomaterials | Best Researcher Award

Published on by Cell Biologist

Dr. Xin Li | Biomaterials | Best Researcher Award

Dr. Xin Li , The Chinese University of Hong Kong , Hong Kong

Dr. Xin Li is a dynamic and prolific researcher in the field of biomedical polymer materials and nanomedicine. With a Ph.D. from RWTH Aachen University under the mentorship of Prof. Andrij Pich, Dr. Li has carved a niche in responsive nanogels, ultrasound-triggered drug delivery, and smart biosensors. He currently holds a position as a Research Associate at The Chinese University of Hong Kong, following a postdoctoral fellowship at HKUST. Dr. Li has published over 70 SCI-indexed papers, earned 2600+ citations, holds 10 patents, and contributed to one academic book. His research stands out in top-tier journals like Nature Communications, Chem, Matter, and Advanced Materials. Recognized globally, he has led several high-impact research projects and received prestigious honors such as the 2024 JPA Prize and the 2021 Young Scientist Award. Dr. Li’s innovative mindset and cross-disciplinary expertise continue to push boundaries in biomedical engineering.

Publication Profile:

Scopus

✅ Strengths for the Award:

  1. Outstanding Publication Record 📚
    Dr. Li has authored over 70 SCI-indexed publications in top-tier journals such as Nature Communications, Chem, Matter, Advanced Materials, and Angewandte Chemie. With an H-index of 32 and 2600+ citations, he demonstrates a strong impact in his field.

  2. Innovative and Translational Research 💡
    His work focuses on stimuli-responsive nanogels, mechanophore-based drug delivery, and biosensors, directly addressing real-world medical challenges like cancer therapy and infection monitoring.

  3. Leadership in International Projects 🌏
    Dr. Li has served as Principal Investigator and Co-leader of prestigious funding programs, including the Shanghai Overseas High-level Young Talent Program, Pujiang Program, and a Sino-German Research Grant, totaling over ¥1 million and €257,000.

  4. Interdisciplinary Expertise 🔬
    With a background in polymeric materials, biomedical engineering, and biophysics, he bridges the gap between material science and clinical applications, pushing the boundaries of modern nanomedicine.

  5. Recognized Honors and Editorial Roles 🏆
    Awards like the 2024 JPA Prize and the 2021 Young Scientist Award, along with his editorial contributions, highlight both his recognition and thought leadership in the scientific community.

⚠️ Areas for Improvement:

  1. Broader Industry Collaboration
    While Dr. Li has a strong academic and funding track record, increasing collaboration with biotech or pharmaceutical industries could further enhance the translational value of his research.

  2. Public Engagement and Science Communication
    As his work involves complex and novel biomedical technologies, more active engagement in science communication or public-facing platforms could broaden the reach and societal impact of his innovations.

  3. Diversified International Experience
    Though already globally active (Germany, China, Hong Kong), involvement in North American or broader EU collaborative networks might further strengthen his research diversity and global visibility.

🎓 Education:

Dr. Xin Li holds a Ph.D. in Biomedical Polymer Materials from RWTH Aachen University, Germany (2018–2023), where he worked under Prof. Andrij Pich, focusing on functional nanogels and stimuli-responsive systems for precise therapy. Prior to this, he earned an M.S. in Biomedical Engineering from Donghua University (2014–2017), supervised by Prof. Xiangyang Shi, with work centered around nanomaterials for gene and drug delivery. His academic journey began with a B.E. in Polymeric Materials and Engineering from Zhejiang A & F University (2010–2014), mentored by Prof. Pingan Song and Prof. Liang Chen. Across each academic stage, Dr. Li demonstrated an impressive aptitude for interdisciplinary innovation, combining materials science, chemical engineering, and biomedical applications. His strong educational foundation set the stage for his successful research career in developing next-generation nanomedicines and imaging technologies.

💼 Experience:

Dr. Xin Li currently serves as a Research Associate at The Chinese University of Hong Kong (2024–present), advancing cutting-edge research in nanomedicine. Prior to this, he was a Postdoctoral Fellow at The Hong Kong University of Science and Technology (2023–2024), where he expanded his expertise in responsive nanomaterials. His earlier research assistant roles at the DWI-Leibniz Institute (2022–2023) and Donghua University (2017) enriched his multidisciplinary experience. During his doctoral training at RWTH Aachen, Dr. Li led multiple collaborations and mentored students, reflecting his leadership potential. He has independently secured and led major grants like the Shanghai Overseas High-level Young Talent Program and the Pujiang Program. Dr. Li’s professional trajectory demonstrates a steady rise marked by impactful research, international collaboration, and continuous innovation in materials for imaging, therapy, and diagnostics.

🏅 Awards and Honors:

Dr. Xin Li has been consistently recognized for his contributions to biomedical engineering and nanomedicine. In 2024, he received the JPA Prize for his role as an Excellent Young Editorial Board Member. Earlier, in 2021, he was honored with the Young Scientist Award at the 3rd Global Experts Meeting on Chemistry and Medicinal Chemistry, acknowledging his innovative research in responsive drug delivery systems. He also earned the CSC-RWTH Scholarship in 2017, awarded by the China Scholarship Council for his doctoral studies in Germany, reflecting academic excellence and international research promise. In addition to these accolades, he has been entrusted with leadership roles in competitive grant programs such as the Shanghai Overseas High-level Talent Plan and the Sino-German Center collaborative research grant. These honors highlight Dr. Li’s status as an emerging leader in translational nanomedicine and interdisciplinary biomedical research.

🔬 Research Focus:

Dr. Xin Li’s research focuses on the design and development of stimuli-responsive nanogels, ultrasound-activated drug delivery systems, and smart biosensors. He is particularly interested in leveraging physical triggers (e.g., ultrasound, radiotherapy) to enable precise drug activation, offering high specificity and minimal side effects. His work on polymer mechanochemistry and hydrogel-based biosensors has opened new frontiers in non-invasive cancer therapy, infection monitoring, and imaging. With a deep understanding of polymer physics, biomedical engineering, and nanotechnology, Dr. Li integrates multiple disciplines to tackle challenges in tumor-targeted delivery, photothermal therapy, and metabolic reprogramming. His future focus includes developing clinically translatable systems for real-time therapy monitoring, immune modulation, and personalized medicine. By combining fundamental research with practical applications, Dr. Li aims to revolutionize how diseases like cancer and infections are diagnosed and treated.

📚 Publications Top Notes:

  1. 🧬 Transvascular transport of nanocarriers for tumor delivery, Nat. Commun., 2024

  2. 🧠 Leukocyte-nanomedicine system for targeted delivery and precise theragnostics, Chem, 2022

  3. 🩹 A wireless and battery-free DNA hydrogel biosensor for wound infection monitoring, Matter, 2022

  4. 💊 Radiotherapy-triggered prodrug activation: A new era in precise chemotherapy, Med, 2022

  5. 🧪 Engineered living hydrogels for robust biocatalysis in pure organic solvents, Cell Rep. Phys. Sci., 2022

  6. ☢️ Radiotherapy activated systems for precise tumor treatment, Nat. Rev. Cancer, 2025

  7. 💧 Sprayed aqueous microdroplets for spontaneous synthesis of functional microgels, Angew. Chem. Int. Ed., 2025

  8. 🧬 Functional dendrimer nanogels for DNA delivery and gene therapy of tumors, Angew. Chem. Int. Ed., 2025

  9. 🔥 Global cold local photothermal-mediated synergistic metabolic antitumor immunity, Adv. Mater., 2025

  10. 📡 Network topology of nanogels regulates mechanophore activation for ultrasound-mediated therapy, Angew. Chem. Int. Ed., 2025

🧾 Conclusion:

Dr. Xin Li is highly suitable and deserving of the Best Researcher Award. His exceptional research output, innovative project leadership, and contributions to translational biomedical science place him among the leading young researchers globally. While there is room for expanding industry ties and global engagement, his trajectory, impact, and recognition already demonstrate excellence well above typical benchmarks. Dr. Li exemplifies the future of interdisciplinary research and is a valuable asset to the global scientific community.