Xiaozhi Liu | Cell-Cell Communication | Best Researcher Award

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Prof. Xiaozhi Liu | Cell-Cell Communication | Best Researcher Award

Prof. Xiaozhi Liu, Tianjin Fifth Central Hospital, China

Dr. Xiaozhi Liu, born on December 10, 1979, is a distinguished medical researcher and Director of the Central Laboratory at Tianjin Fifth Central Hospital. With over two decades of experience in neurosurgery and translational research, he has made substantial contributions in neural regeneration and SUMOylation-related mechanisms. Dr. Liu is a prolific academic with numerous publications in top-tier journals and active involvement in multiple National Natural Science Foundation of China projects. His international exposure as a visiting scholar at Duke University Medical Center (2012–2013) enhanced his global scientific perspective. Dedicated to neuroscience innovation, he combines advanced molecular biology techniques with clinical applications to improve patient outcomes in neurological disorders. Recognized for his scientific rigor, leadership, and innovative research approach, Dr. Liu is an exceptional candidate for the Best Researcher Award.

Publication Profile: 

Orcid

✅ Strengths for the Award:

  1. Innovative Research Focus: Dr. Liu’s expertise in SUMOylation, neural regeneration, and gene regulation presents a cutting-edge approach to treating cerebral ischemia, glioblastoma, and cardiac injury.

  2. Strong Grant History: He has led multiple prestigious National Natural Science Foundation of China (NSFC) projects as both PI and co-investigator, with substantial funding and scientific merit.

  3. Impressive Publication Record: Over 15 peer-reviewed publications in impactful journals (Stroke, Aging, Neuroscience, etc.), with topics ranging from brain ischemia to cardiac injury, illustrate interdisciplinary strength.

  4. Leadership Role: As Director of the Central Laboratory, he demonstrates strong research management, mentoring, and institutional collaboration capabilities.

  5. Global Perspective: His time as a visiting scholar at Duke University Medical Center enhanced his academic and cross-cultural research competencies.

  6. Clinical & Basic Science Integration: Combines bench-to-bedside applications, especially in neurosurgery and molecular biology.

⚠️ Areas for Improvement:

  1. International Outreach: While academically robust in China, Dr. Liu could benefit from increased global collaboration, co-authorship with foreign institutes, or keynote speaking roles at international conferences.

  2. Patent & Innovation Translation: There’s potential to strengthen the translational commercialization of his research findings through patents or biotech partnerships.

  3. Public Engagement: Increasing public science communication and media presence could enhance his visibility in broader scientific and policy-making communities.

🎓 Education Background:

Dr. Xiaozhi Liu began his academic journey at Zhangjiakou Medical College, completing a degree in Clinical Medicine in 2003. He pursued his passion for neurosurgery at Tianjin Medical University, where he earned a master’s degree in 2007 and later a Ph.D. in 2017. His academic pursuit extended internationally with a one-year research fellowship at the Duke University Medical Center in the United States (2012–2013), where he specialized in neurosurgical studies. Throughout his academic training, Dr. Liu has demonstrated a deep commitment to the integration of clinical knowledge with cutting-edge biomedical research, particularly in the areas of neuroregeneration and molecular neuroscience. His academic background laid a strong foundation for his contributions to neurobiology, clinical translation, and innovative research in SUMOylation, gene expression regulation, and therapeutic interventions for neurological diseases.

🏥 Work Experience:

Dr. Liu began his clinical career as a Neurosurgery Resident at the Affiliated Hospital of the Chinese People’s Armed Police Force Medical College from 2007 to 2009. He then served as a physician in the Department of Neurosurgery at Tianjin Fifth Central Hospital until 2012. Since December 2013, he has been serving as the Director of the Central Laboratory at the same institution. In this role, he has spearheaded major research initiatives and supervised clinical translational projects in neurobiology. His leadership has been instrumental in establishing a multidisciplinary research environment that bridges clinical neuroscience and molecular biology. His extensive experience in both hospital-based patient care and laboratory-based scientific discovery places him at the intersection of clinical excellence and research innovation. His career trajectory reflects an unwavering commitment to advancing medical science and improving patient care.

🔬 Research Focus:

Dr. Xiaozhi Liu’s research centers on the molecular mechanisms of neuroregeneration, focusing particularly on SUMOylation, gene expression modulation, and neural stem cell therapy. His work explores the protective roles of SUMO-modified proteins in ischemic stroke, glioblastoma suppression, and spinal cord injury recovery. Dr. Liu investigates the role of small RNAs, mitochondrial dynamics, and oxidative stress in neurodegenerative conditions and cardiovascular diseases. His approach combines genomic, proteomic, and cell-based assays to understand the therapeutic potential of modulating cellular stress responses. Ongoing collaborations on stem cell transplantation, chromatin remodeling in cardiac diseases, and translational neuroscience further exemplify his dedication to interdisciplinary science. With an extensive list of national research grants and peer-reviewed publications, Dr. Liu remains at the forefront of biomedical innovations aimed at reversing tissue damage and enhancing neuroplasticity.

📚 Publication Top Notes:

  1. 🧠 Small ubiquitin-like modifier 3-modified proteome regulated by brain ischemia in transgenic mice – Stroke, 2014

  2. 🧬 Interactions of connexin 43 and aquaporin-4 in glioma-induced brain edema – Mol Med Rep, 2015

  3. 🧠 Neuron-specific SUMO knockdown worsens outcome after brain ischemia in mice – Neuroscience, 2017

  4. 🦴 Silencing Ubc9 suppresses osteosarcoma and enhances chemosensitivity via Connexin 43 SUMOylation – Int J Oncol, 2018

  5. ❤️ SERCA2a: a key protein in the calcium cycle of heart failure – Heart Fail Rev, 2019

  6. 💓 Zinc-induced SUMOylation of Drp1 protects heart from ischemia-reperfusion injury – Oxid Med Cell Longev, 2019

  7. 🧠 Genetic polymorphisms and transcription in intracranial aneurysm involving NOTCH3 – Aging (Albany NY), 2019

  8. 🧪 Saikosaponin-d inhibits hepatoma and enhances chemosensitivity via SENP5-dependent Gli1 SUMOylation – Front Pharmacol, 2019

  9. 🧬 Parkin and Nrf2 prevent apoptosis in endplate chondrocytes via mitophagy – Life Sci, 2019

  10. 🧫 MitoQ protects against disc degeneration by targeting mitochondrial dysfunction – Cell Prolif, 2020

🧾 Conclusion:

Dr. Xiaozhi Liu stands out as a highly qualified and deserving candidate for the Best Researcher Award. His blend of clinical neurosurgery, translational laboratory research, and molecular innovation, particularly in SUMOylation and neuroprotection, positions him at the forefront of modern biomedical science in China. With a leadership role in a major hospital, strong national research recognition, and a substantial academic footprint, he exemplifies excellence in research and mentorship.

Lingyan Zhou | Cell Death Pathway | Best Researcher Award

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Dr. Lingyan Zhou | Cell Death Pathway | Best Researcher Award

Dr. Lingyan Zhou , Shandong Provincial Hospital Affiliated to Shandong First Medical University , China

Dr. Lingyan Zhou is a dedicated neuroscientist and clinician specializing in the pathogenesis of neurodegenerative diseases, including Alzheimer’s and Parkinson’s disease. Currently serving in the Department of Neurology at Shandong Provincial Hospital affiliated with Shandong First Medical University, Dr. Zhou holds a doctorate and has made notable contributions to neurodegeneration research through high-impact publications and cutting-edge studies. Her work focuses on molecular mechanisms such as protein aggregation, homocysteinylation, and neuroprotection, with particular attention to α-synuclein and DJ-1. Dr. Zhou has co-authored more than 15 peer-reviewed articles in top-tier journals like Nature Communications, Science Advances, and Aging Cell, earning recognition for her insights into disease-modifying pathways. A researcher with a strong translational focus, she bridges the gap between bench and bedside, aiming to develop therapeutic strategies that can mitigate or reverse neurodegenerative processes. Her commitment to science and patient-centered research makes her a strong candidate for the Best Researcher Award.

Publication Profile:

Orcid

✅ Strengths for the Award:

  1. Strong Publication Record in High-Impact Journals
    Dr. Zhou has consistently published in top-tier journals such as Nature Communications, Science Advances, Aging Cell, and Movement Disorders, reflecting the significance and innovation of her work. Many of these are Q1 journals with high impact factors.

  2. Focused Research on Neurodegeneration
    Her core focus on the molecular basis of Alzheimer’s and Parkinson’s disease, especially novel mechanisms like N-homocysteinylation, STAT1-PARP1, and microRNA signaling, demonstrates depth and relevance to global health priorities.

  3. Translational Impact
    Her research bridges basic science and clinical application, particularly through studies on neuroprotection, early disease biomarkers, and potential therapeutic targets.

  4. Early Career Excellence
    Despite being in the early stages of her career, Dr. Zhou has already authored or co-authored over 17 peer-reviewed publications, many as first or corresponding author, which is exceptional at this stage.

  5. Multidisciplinary Collaborations
    Dr. Zhou’s collaborations with experts across genetics, immunology, bioinformatics, and neurology highlight her integrative approach to complex diseases.

  6. International Visibility
    Multiple articles are indexed in PubMed, Crossref, and DOIs, showing her research has international academic presence and reach.

⚠️ Areas for Improvement:

  1. Greater International Exposure
    While her publication record is strong, further participation in international neuroscience conferences, workshops, or global consortia would enhance visibility and foster leadership roles.

  2. Grant Leadership and Independent Funding
    As she progresses, securing independent research funding and leading grant-funded projects will further demonstrate research independence and strengthen her candidacy for top-tier awards.

  3. Mentorship and Teaching Roles
    Involvement in structured mentorship or supervision of Ph.D./postdoctoral researchers could be better highlighted to show contributions to research training and capacity building.

  4. Innovation Translation Pathway
    Filing patents or initiating translational collaborations with biotech/pharma could underline the practical applicability of her findings.

🎓 Education:

Dr. Lingyan Zhou received her doctorate from Wuhan University, one of China’s leading research institutions, between September 2020 and June 2023. During her Ph.D. training, she developed expertise in molecular neuroscience and translational medicine, with a specific focus on the pathological mechanisms underlying Parkinson’s and Alzheimer’s diseases. Her research explored cellular stress pathways, protein misfolding, and epigenetic regulation in neurodegeneration, leading to multiple first-author publications in high-impact journals. Her academic background provided a solid foundation in experimental techniques such as immunohistochemistry, gene expression analysis, and in vivo disease modeling. The interdisciplinary approach at Wuhan University enriched her understanding of both clinical neurology and basic neuroscience. This rigorous academic training has equipped Dr. Zhou with the analytical and research skills necessary for advancing innovation in neurodegenerative disease treatment.

🧪 Experience:

Since July 2023, Dr. Lingyan Zhou has been serving in the Department of Neurology at Shandong Provincial Hospital affiliated with Shandong First Medical University, where she engages in both clinical practice and translational neuroscience research. Prior to that, she completed her doctoral studies at Wuhan University, where she developed a deep interest in the role of homocysteine metabolism and genetic regulation in Parkinson’s disease. Over her career, she has collaborated with multidisciplinary teams to investigate molecular and cellular mechanisms of neurodegeneration and published extensively in internationally recognized journals. Her current position allows her to continue high-impact research while mentoring junior colleagues and participating in multi-center studies. Her combined experience in basic research, clinical neurology, and academic collaboration has established her as a key contributor in the field of neurodegenerative diseases, positioning her well for leadership roles and research recognition such as the Best Researcher Award.

🧠 Research Focus:

Dr. Lingyan Zhou’s research is centered on understanding the molecular and cellular mechanisms that drive neurodegenerative diseases, with an emphasis on Alzheimer’s and Parkinson’s disease. Her work has shed light on pathological protein modifications, such as N-homocysteinylation of α-synuclein and DJ-1, which contribute to protein aggregation and neurotoxicity. Additionally, she investigates the neuroprotective roles of vitamins, retinoic acid, and microRNAs in slowing disease progression. Dr. Zhou is also exploring how infectious diseases like SARS-CoV-2 may trigger or exacerbate neurological disorders, expanding the understanding of systemic factors in brain health. Her studies leverage both in vitro and in vivo models to unravel pathways involving STAT1, PARP1, and Notch signaling. By identifying potential therapeutic targets and biomarkers, her research aims to guide the development of novel treatment strategies that could improve outcomes for patients suffering from movement disorders and cognitive decline.

📚 Publications Top Notes:

  1. 🧪 N-homocysteinylation of alpha-synuclein promotes its aggregation and neurotoxicity – Aging Cell (2022)

  2. 🧠 Association of vitamin B2 intake with cognitive performance in older adults: a cross-sectional study – J Transl Med (2023)

  3. 🧬 Homocysteine and Parkinson’s disease – CNS Neurosci Ther (2023)

  4. 🧴 Retinoic Acid Prevents alpha-Synuclein Preformed Fibrils-Induced Toxicity via Inhibiting STAT1-PARP1 Signaling – Mol Neurobiol (2023)

  5. 🧫 N-homocysteinylation of DJ-1 promotes neurodegeneration in Parkinson’s disease – Aging Cell (2024)

  6. 🦠 SARS-CoV-2: Underestimated damage to nervous system – Travel Med Infect Dis (2020)

  7. 💊 Potential therapeutic drugs for ischemic stroke based on bioinformatics analysis – Int J Neurosci (2019)

  8. 🧬 PTPN22 Gene Polymorphisms and Stroke Susceptibility – Dis Markers (2019)

  9. 🧪 IL-18 Gene Polymorphisms and Risk of Ischemic Stroke: A Meta-analysis – Neuroreport (2019)

  10. 🚬 Aromatic hydrocarbon receptor links smoking and rheumatoid arthritis – Clin Exp Rheumatol (2020)

🧾 Conclusion:

Dr. Lingyan Zhou demonstrates an exceptional trajectory for a young neuroscience researcher. Her deep and original contributions to unraveling molecular mechanisms in neurodegeneration, particularly Parkinson’s and Alzheimer’s disease, make her highly deserving of recognition. The breadth and quality of her publication record—combined with her translational outlook—signal a rising star in neurodegenerative disease research.

Balbino Alarcón | Cancer Cell Biology | Best Researcher Award

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Prof. Dr. Balbino Alarcón | Cancer Cell Biology | Best Researcher Award

Prof. Dr. Balbino Alarcón , Consejo Superior de Investigaciones Científicas , Spain

Balbino Alarcón is a leading Spanish immunologist renowned for his contributions to T cell biology and immune signaling. Currently serving as Profesor de Investigación at the Consejo Superior de Investigaciones Científicas (CSIC), he has been affiliated with the Centro de Biología Molecular Severo Ochoa since 2002. His research has played a pivotal role in uncovering mechanisms of T cell receptor (TCR) signaling and immune system regulation. Dr. Alarcón holds a PhD in Biology from the Universidad Autónoma de Madrid, where he began shaping his scientific journey in the early 1980s. Over the decades, he has authored numerous impactful publications, many in top-tier journals, and holds several patents licensed to biotech companies. His work bridges fundamental immunology with translational applications in autoimmunity and cancer. With a keen focus on molecular signaling, his research continues to influence both basic science and therapeutic innovation in immunology.

Publication Profile:

Google Scholar

✅ Strengths for the Award:

  1. Outstanding Research Contributions:
    Dr. Alarcón has made seminal contributions to immunology, especially in T cell receptor (TCR) signaling, immune synapse formation, and immune cell communication. His work has appeared in top-tier journals like Cell, Immunity, Nature Communications, and Journal of Experimental Medicine.

  2. Impactful Publications & Citations:
    His research includes several highly cited papers (e.g., >500 citations), underlining the influence of his work on the broader scientific community.

  3. Translational Achievements:
    He holds multiple patents on immunomodulatory molecules (e.g., AX-024), which were licensed to biotech company Artax Biopharma, bridging basic science and clinical application.

  4. SARS-CoV-2 Research Leadership:
    He actively contributed to COVID-19 immunity research, developing flow cytometry-based antibody detection techniques and tracking longitudinal immune responses to infection and vaccination.

  5. Longevity and Commitment:
    Over 40 years of consistent research activity, with continuous affiliation to one of Spain’s most prestigious scientific institutions, CSIC.

  6. International Collaboration:
    He co-authored papers with leaders in immunology, showing global recognition and collaboration.

🛠️ Areas for Improvement:

  • Public Engagement & Visibility:
    Despite scientific acclaim, more visibility in public science communication, conference keynote roles, or leadership in global immunology consortia would further support his candidacy.

  • Mentorship Highlighting:
    While his academic stature suggests mentorship, documentation or awards for training young scientists could enhance his profile for broader awards recognizing holistic impact.

  • Innovation Metrics:
    Increased emphasis on clinical translation or successful product development from his patents could strengthen claims to innovation-driven recognitions.

🎓 Education:

Dr. Balbino Alarcón completed his undergraduate degree (Licenciado en Biología) in 1982 and his PhD in Biology with a specialization in Biochemistry in 1985, both from the Universidad Autónoma de Madrid, Spain. During his academic formation, he developed a deep interest in immunological signaling, particularly in how T cells communicate with their environment. His early education laid the foundation for a distinguished research career that has spanned more than three decades. His doctoral studies were focused on cellular and molecular immunology, equipping him with the tools to explore intricate signaling pathways. This robust educational background positioned him for leadership roles in immunological research, both nationally and internationally. Through rigorous academic training and continuous research contributions, Dr. Alarcón has become a key figure in advancing our understanding of T cell function and immune regulation.

👨‍🔬 Experience:

Dr. Balbino Alarcón has over 40 years of experience in immunological research, with a primary focus on T cell receptor (TCR) signaling and lymphocyte activation. Since July 27, 2002, he has held the position of Profesor de Investigación at the Consejo Superior de Investigaciones Científicas (CSIC), working at the Centro de Biología Molecular Severo Ochoa in Madrid, Spain. His academic and research career began with groundbreaking studies in T cell immunobiology, leading to discoveries such as the role of conformational changes in TCR activation. Dr. Alarcón has also been deeply involved in translational research, co-developing immunomodulatory drugs and securing patents that were licensed to Artax Biopharma. He regularly collaborates with leading immunologists and institutions worldwide, contributing to high-impact publications and international scientific reviews. His expertise and sustained contributions have made him a mentor and authority in molecular immunology and T cell biology.

🏅 Awards and Honors:

Dr. Balbino Alarcón’s distinguished career is highlighted by several prestigious awards and intellectual property recognitions. He co-developed two patented immunosuppressive strategies based on TCR signaling inhibition: one disrupting the TCR-Nck interaction and another involving chromene derivatives. Both patents were licensed to Artax Biopharma, showcasing the real-world therapeutic relevance of his research. He has authored highly cited publications, including foundational work published in Cell, Immunity, and Annual Review of Immunology, with citations in the hundreds. These contributions have not only advanced the field of immunology but also positioned Dr. Alarcón as a thought leader in immune signal transduction. He has been recognized nationally and internationally for his scientific achievements, serving as an editorial contributor and co-author of influential immunological reviews. His work continues to shape both academic and pharmaceutical research, making him a strong candidate for Best Researcher Awards.

🔬 Research Focus:

Dr. Alarcón’s research centers on the molecular mechanisms governing T cell receptor (TCR) activation and signal transduction. His work dissects how T cells recognize antigens and how intracellular signaling cascades translate these interactions into immune responses. A significant aspect of his research has involved understanding the conformational dynamics of the TCR/CD3 complex and how this affects T cell sensitivity and activation thresholds. He also explores the role of RRas2 in T and B cell function, including its relevance in lymphomagenesis and autoimmunity. Recently, he has contributed to understanding immune responses to SARS-CoV-2 and methods to detect neutralizing antibodies. His interdisciplinary approach integrates cell biology, molecular immunology, and translational research, linking fundamental science to clinical applications such as vaccine development and immunotherapy. By targeting TCR-associated pathways, Dr. Alarcón’s research opens new avenues in the treatment of immune-related diseases and cancer.

📚 Publications Top Notes:

  1. 🧫 RRas2 is required for germinal center formation to aid B cells during energetically demanding processes (Sci Signal, 2018)

  2. 🧪 A window of opportunity for cooperativity in the T Cell Receptor (Nat Commun, 2018)

  3. 🧬 Antigen phagocytosis by B cells is required for a potent humoral response (EMBO Rep, 2018)

  4. ⚙️ RRAS2 shapes the TCR repertoire by setting the threshold for negative selection (J Exp Med, 2019)

  5. 💊 Small molecule AX-024 targets T cell receptor signaling by disrupting CD3ε-Nck interaction (J Biol Chem, 2020)

  6. 🧪 Flow cytometry multiplexed method for the detection of Neutralizing human antibodies to SARS-CoV-2 (EMBO Mol Med, 2021)

  7. 🧬 Antigen presentation between T-cells drives Th17 polarization under limiting antigen (Cell Rep, 2021)

  8. 🧫 Detection of sustained humoral immune response (IgG + IgA) in SARS-CoV-2 infection (Sci Rep, 2021)

  9. 🧠 SFRP1 modulates astrocyte-to-microglia crosstalk in neuroinflammation (EMBO Rep, 2021)

  10. 💉 Longitudinal dynamics of SARS-CoV-2-specific immunity after infection or vaccination (PLoS Pathog, 2021)

🧾 Conclusion:

Dr. Balbino Alarcón is a highly deserving candidate for the Best Researcher Award. His pioneering studies in T cell signaling, impactful biomedical patents, and active role in immune response to infectious diseases demonstrate excellence in both basic and translational immunology. With decades of productive research, interdisciplinary collaboration, and consistent scientific leadership, he embodies the qualities celebrated by such an award.

Raphaël Rodriguez | Molecular Mechanisms Signaling | Best Researcher Award

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Prof. Raphaël Rodriguez | Molecular Mechanisms Signaling | Best Researcher Award

Prof. Raphaël Rodriguez , CNRS, Institut Curie, France

Raphaël Rodriguez, born October 27, 1978, in Avignon, France, is a pioneering chemical biologist and Research Director at CNRS, Principal Investigator at Institut Curie, and holder of the Skłodowska-Curie Chair of Chemical Biology. A French citizen with two children, Lucía del Mar and Aramis, Rodriguez is renowned for bridging chemistry and biology to unlock the molecular secrets of cancer and inflammation. Trained in the UK under legendary scientists Sir J. E. Baldwin, Sir S. Balasubramanian, and Sir S. P. Jackson, he returned to France to launch groundbreaking research on ferroptosis and metal regulation in cell adaptation. His entrepreneurial and academic excellence earned him numerous accolades, including the National Order of Merit. With more than 130 publications and several successful biotech ventures, Rodriguez continues to shape the future of medical science with bioactive molecules like Ironomycin and Pyridostatin. He is an editorial board member, reviewer, teacher, and a public voice on science.

Publication Profile:

Google Scholar

✅ Strengths for the Award:

  1. Pioneering Scientific Impact:
    Dr. Rodriguez has contributed over 130 high-impact publications in top-tier journals like Nature, Science, JACS, Nature Chemistry, and Cell Metabolism. His work has helped define ferroptosis, a form of programmed cell death, and metal regulation in cancer—a game-changing area in molecular medicine.

  2. Innovation & Translation:
    He discovered and commercialized small molecules such as Pyridostatin, Ironomycin, and Supformin, directly impacting both science and therapeutics. His work bridges fundamental science and drug discovery.

  3. Leadership & Mentorship:
    From mentoring under renowned scientists to leading his own lab at Institut Curie, he has shaped France’s next generation of researchers in chemical biology.

  4. Recognition & Awards:
    His extensive list of prestigious awards, including the CNRS Silver Medal, Liliane Bettencourt Prize, and Knight of the National Order of Merit, reflect peer recognition on national and international levels.

  5. Entrepreneurship:
    As a co-founder of biotech companies (e.g., Adrestia Therapeutics, later acquired), he has demonstrated a rare capacity to translate discoveries into clinical and commercial value.

  6. Scientific Influence:
    Editorial board memberships and frequent invitations to over 160 major conferences show his reputation as a global thought leader in his field.

🔧 Areas for Improvement:

  1. Public Engagement Scaling:
    Although Dr. Rodriguez is active in media (radio, TV, print), expanding international science outreach (e.g., global science festivals, public lectures, social media presence) could help further democratize his scientific message.

  2. Clinical Translation:
    While several molecules from his lab are commercialized, more direct clinical trials or FDA approvals tied to his molecules would elevate his impact from bench to bedside.

  3. Collaborative Diversity:
    Encouraging more global South collaborations or mentorships could help broaden his lab’s international footprint and contribute to equitable science capacity building.

🎓 Education:

Raphaël Rodriguez’s academic journey is marked by elite training and impactful credentials across Europe. He earned his PhD in Chemistry (2002–2005) through a joint program between Marseille and Oxford. He then pursued postdoctoral research as a Senior Research Associate at Cambridge’s Department of Chemistry and Gurdon Institute (2005–2012), where he developed skills at the interface of chemistry and biology. In 2012, he obtained the prestigious Habilitation à Diriger des Recherches from the University of Paris-Saclay, enabling him to supervise PhD candidates and lead independent research. His rise through the academic ranks was rapid: he became a CNRS Group Leader in 2012, then Principal Investigator at Institut Curie in 2015. In 2017, he was promoted to Research Director (DR1) at CNRS. In 2020, he was awarded the Skłodowska-Curie Chair of Chemical Biology at Institut Curie. His interdisciplinary training under world-renowned mentors has uniquely positioned him at the forefront of chemical biology research.

💼 Experience:

Raphaël Rodriguez’s professional experience is a blend of high-level research, leadership, and innovation. He began his postdoctoral career at the University of Cambridge (2005–2012), working in the Department of Chemistry and the Gurdon Institute. In 2012, he became a CNRS Group Leader at ICSN, Gif-sur-Yvette, launching his independent research career. In 2015, he transitioned to Institut Curie as a Principal Investigator, where he deepened his focus on cancer and inflammation. His promotion to Research Director (DR1) at CNRS in 2017 reflects his impact and leadership. Awarded the Skłodowska-Curie Chair of Chemical Biology in 2020, Rodriguez oversees a productive lab that investigates ferroptosis, DNA structure, and metal ion regulation in disease. He is also an entrepreneur, co-founding Adrestia Therapeutics and OrbiThera. He teaches at PSL University, organizes international conferences, and contributes to editorial boards and scientific advisory boards worldwide, maintaining a strong presence in both academia and biotech.

🏆 Awards and Honors:

Raphaël Rodriguez has received an impressive array of honors, showcasing his impact on science and innovation. In 2024 alone, he won the CNRS Silver Medal and the Ligue Contre le Cancer Duquesne Prize. His earlier recognition includes the prestigious Liliane Bettencourt Prize for Life Sciences (2023), the Knight of the National Order of Merit (2022, presented by Nobel Laureate Jean-Marie Lehn), and the Klaus Grohe Prize (2022). He has also been awarded the Antoine Lacassagne Prize (Collège de France, 2019), the Sunrise Cancer Stem Cell Award (2019), the Charles Defforey–Institut de France Prize (2019), and the Tetrahedron Young Investigator Award (2019). Rodriguez is a Fellow of the Royal Society of Chemistry (2018) and won the Pierre Fabre Award for Therapeutic Innovation (2015). These accolades affirm his contributions across cancer research, chemical biology, and molecular therapeutics, as well as his success in translating science into societal benefit through entrepreneurship.

🔍 Research Focus:

Raphaël Rodriguez’s research lies at the cutting edge of chemical biology, with a focus on understanding how cells adapt to stress, particularly in the contexts of cancer and inflammation. His laboratory explores the role of metal ions—especially iron—as regulators of cellular plasticity and fate. Notably, his team discovered mechanisms underlying ferroptosis, a form of regulated cell death linked to iron metabolism, and how this can be exploited for anti-cancer therapies. He also investigates non-canonical DNA structures like G-quadruplexes, using small molecules to study and manipulate gene regulation. His lab has developed and commercialized several potent bioactive compounds, including Pyridostatin, Remodelin, Ironomycin, and Supformin, which are used both as research tools and potential therapeutics. Rodriguez combines molecular design, cell biology, and translational strategies, making his work a blueprint for chemical biology-driven precision medicine. He continues to raise significant research funding and actively collaborates across academia and biotech.

📚 Publications Top Notes:

  1. 🧬 Small-molecule–induced DNA damage identifies alternative DNA structures in human genes – Nature Chemical Biology

  2. ⚙️ Salinomycin kills cancer stem cells by sequestering iron in lysosomes – Nature Chemistry

  3. 🛡️ A novel small molecule that alters shelterin integrity and triggers a DNA-damage response at telomeres – JACS

  4. 🧫 Chemical inhibition of NAT10 corrects defects of laminopathic cells – Science

  5. 🧠 The transcription factor FOXM1 is a cellular target of the natural product thiostrepton – Nature Chemistry

  6. 🧪 Trisubstituted isoalloxazines as a new class of G-quadruplex binding ligands – JACS

  7. 🔥 PML-regulated mitochondrial metabolism enhances chemosensitivity in human ovarian cancers – Cell Metabolism

  8. 🔬 A single-molecule platform for investigation of G-quadruplex interactions with small-molecule ligands – Nature Chemistry

  9. 🧲 Small-molecule-mediated G-quadruplex isolation from human cells – Nature Chemistry

  10. 🧬 CD44 regulates epigenetic plasticity by mediating iron endocytosis – Nature Chemistry

  11. 🧷 Selective RNA vs DNA G-Quadruplex Targeting by In Situ Click Chemistry – Angewandte Chemie

  12. 🧬 G-Quadruplex-Binding Benzo[a]phenoxazines Down-Regulate c-KIT Expression in Gastric Carcinoma Cells – Journal of Medicinal Chemistry

🧾 Conclusion:

Dr. Raphaël Rodriguez exhibits exceptional merit and impact across the entire research ecosystem—fundamental science, innovation, mentorship, and commercialization. His trailblazing work in chemical biology, coupled with a record of scientific leadership and entrepreneurship, makes him highly deserving of the Best Researcher Award. His career reflects a rare blend of depth, vision, and cross-disciplinary innovation. Minor enhancements in global public engagement and clinical integration could further elevate his already stellar profile.

Mai Kadry | Biochemistry | Best Researcher Award

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Assist. Prof. Dr. Mai Kadry | Biochemistry | Best Researcher Award

Assist. Prof. Dr. Mai Kadry  , NRC , Egypt

Dr. Mai Osman Mohamed Kadry is an Assistant Professor at the Therapeutic Chemistry Department of the National Research Centre in Egypt, specializing in molecular and biochemical research. With over two decades of experience, she has contributed significantly to the advancement of therapeutic chemistry. Dr. Kadry obtained her PhD in Biochemistry from Cairo University in 2016, focusing on oxidative injury mitigation through antioxidants. She has authored and co-authored multiple articles in prestigious journals. Her research is driven by a passion for finding therapeutic solutions to biochemical challenges, with a focus on molecular mechanisms and drug development.

Publication Profile:

Scopus

Strengths for the Award:

Dr. Mai Osman Mohamed Kadry has made significant contributions to the field of therapeutic chemistry, particularly in molecular and biochemical research. As an Assistant Professor at the National Research Centre (NRC), her dedication to scientific advancement is evident in her research on oxidative stress, drug-induced toxicity, and the potential of nanotechnology to mitigate such effects. Her work has been published in high-impact journals, showcasing her expertise in areas like cancer research, biochemistry, and drug development. Additionally, her comprehensive teaching experience in academic settings has strengthened her ability to impart knowledge to the next generation of researchers.

Areas for Improvement:

Although Dr. Kadry’s work is impressive, her research could further benefit from exploring more collaborative projects across different research centers and incorporating a broader range of interdisciplinary approaches. Engaging with cutting-edge technologies such as AI-driven drug discovery or multi-omics data analysis could significantly expand her impact on therapeutic chemistry.

Education:

Dr. Mai Kadry’s academic journey began with a Bachelor’s degree in Pharmaceutical Sciences from Ain Shams University, graduating with honors in 2003. She later pursued an MSc in Pharmaceutical Sciences with a focus on Biochemistry from Helwan University in 2008. Her doctoral research at Cairo University led to a PhD in Biochemistry in 2016, where she studied the amelioration of oxidative stress induced by titanium dioxide nanoparticles in mice. This educational foundation has equipped her with a robust understanding of biochemistry, molecular biology, and drug therapy.

Experience:

Dr. Mai Kadry has a distinguished career at the National Research Centre (NRC) in Egypt, starting as an Assistant Researcher in 2004 and advancing to Assistant Professor in 2021. Over the years, she has contributed to groundbreaking research in therapeutic chemistry, particularly in the area of oxidative stress and drug toxicity. Dr. Kadry has also taught pharmacognosy at the Faculty of Pharmacy, 6 October University, and served on committees focusing on academic development. Her extensive teaching and research experience positions her as a leader in her field.

Research Focus:

Dr. Mai Kadry’s research focuses on therapeutic chemistry, exploring the molecular mechanisms of drug-induced toxicity, oxidative stress, and potential protective treatments. Her work investigates the impact of nanomaterials like titanium dioxide and their effects on cellular pathways. She also studies the synergistic potential of natural compounds to mitigate damage from toxins, using advanced biochemical methods to evaluate their efficacy. Additionally, Dr. Kadry has a keen interest in cancer research, focusing on autophagy signaling and the development of novel drug formulations.

Publications Top Notes:

  • “Titanium nanostructure mitigating doxorubicin-induced testicular toxicity in rats via regulating major autophagy signaling pathways” 🧬💉
  • “Inflammatory mediators-induced DNA damage in liver and brain injury: Therapeutic approach of 5-Methoy-N-acetyltryptamine” 🧠💊
  • “Necroptosis and autophagy in cisplatinum-triggered nephrotoxicity: Novel insights regarding their prognostic and diagnostic potential” 💊🩺
  • “Resveratrol-based nano-formulations as an emerging therapeutic strategy for ovarian carcinoma” 🎗️💡
  • “miR-122-IGF-1R signaling allied through the dysregulated lncRNA MALAT-1 expression in gastric carcinoma” 🧬🦠
  • “Reciprocal crosslink among MeCP2/BDNF/CREB signaling pinpointed in autism spectrum disorder” 🧠🔬
  • “CRISPR-Cas9 genome and long non-coding RNAs as a novel diagnostic index for prostate cancer therapy” 🧬🧬
  • “Collaboration of Hprt/K-RAS/c-Myc mutation in the oncogenesis of T-lymphocytic leukemia” 🩸⚗️
  • “Thioctic acid shield against lipopolysaccharide depression and endoplasmic reticulum stress: GR7M/Homer/ATF6 signaling” 🧬🛡️
  • “Titanium dioxide nanostructure-loaded Adriamycin surmounts resistance in breast cancer therapy” 🧬🎗️

Conclusion:

Dr. Mai Osman Mohamed Kadry stands out as an exemplary researcher in her field. Her focus on therapeutic chemistry, particularly in relation to oxidative stress, toxicity, and nanotechnology, positions her as a promising candidate for the Researcher of the Year Award. Through her continued contributions and potential for further interdisciplinary collaboration, she will likely continue to make pivotal advancements in the field of molecular and biochemical research.

 

 

 

Chunli Ma | Stem Cell Research | Best Researcher Award

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Ms. Chunli Ma | Stem Cell Research | Best Researcher Award

Ms. Chunli Ma  , Shandong Provincial Hospital Affiliated to Shandong First Medical University , China

Chunli Ma is a Master’s student at Shandong Provincial Hospital Affiliated with Shandong First Medical University in China. With a strong background in Optometry and Vision Science, Ma has expanded into Ophthalmology for her graduate studies. She possesses a deep understanding of ocular disorders and the corresponding diagnostic and treatment protocols. She is passionate about cellular and molecular experimentation, specializing in animal models for scientific research. Her expertise extends to experimental techniques that offer innovative solutions for eye injury and healing. Chunli’s work aims to improve corneal repair, reduce scarring, and enhance treatment outcomes for ocular diseases through advanced therapeutic approaches, including stem cell therapy and specialized eye drops.

Publication Profile:

Orcid

Strengths for the Award:

Chunli Ma is a promising researcher with a strong foundation in both clinical ophthalmology and experimental techniques. Her academic background in Optometry and Vision Science, along with her specialized focus on Ophthalmology, positions her as an emerging leader in the field. Ma’s contributions to the understanding and treatment of corneal injuries, particularly her work on exosomes derived from adipose mesenchymal stem cells and antibacterial eyedrops, have significant therapeutic potential. The formulation of exosomes into eyedrops to aid in rapid corneal healing and prevent scarring, along with the development of multifunctional eyedrops for treating bacterial keratitis, showcases her innovative approach to solving complex clinical challenges. Her ability to translate laboratory research into potential clinical applications is commendable. Moreover, her publications in well-regarded journals and ongoing involvement in impactful research add to her eligibility for the Best Researcher Award.

Areas for Improvement:

While Chunli Ma’s work demonstrates great potential, there are areas where she could continue to develop. Expanding her research to a broader range of ocular conditions beyond corneal injury and keratitis could make her work even more influential across various ophthalmic fields. Additionally, seeking more collaborations with interdisciplinary teams, such as those focusing on the genetic and molecular mechanisms of ocular diseases, could provide deeper insights and enhance her ability to tackle more complex issues. Although she has made valuable contributions to scientific publications, continuing to increase the number and impact of her published papers, especially in top-tier journals, will further solidify her reputation in the scientific community. Gaining experience in patent applications and commercialization of her research could also help bridge the gap between laboratory findings and real-world clinical application.

Education:

Chunli Ma completed her undergraduate degree in Optometry and Vision Science, where she gained foundational knowledge in ocular health and vision correction. Building on this, she pursued a Master’s degree in Ophthalmology, which allowed her to specialize in clinical and experimental ophthalmic research. Her academic journey includes hands-on research in cell biology, molecular techniques, and experimental models to address common ocular disorders, particularly in corneal injury repair. Chunli’s academic training has not only refined her diagnostic skills but also equipped her with cutting-edge knowledge in treatment and therapeutic strategies. Her graduate work bridges practical clinical care with advanced research, focusing on cellular regeneration, stem cell treatments, and tissue healing in the eye. This robust academic background underpins her ongoing commitment to advancing ophthalmic medicine through innovative scientific inquiry and applied research in the field of corneal injury and wound healing.

Experience:

Chunli Ma’s academic journey has been bolstered by hands-on experience in both clinical ophthalmology and cellular research. Her work in experimental ophthalmology has focused on the use of adipose mesenchymal stem cells for corneal repair, creating new methodologies for promoting healing and reducing scarring. She has demonstrated expertise in animal model management and experimentation, gaining insights into complex biological processes affecting eye injuries. Ma has contributed to the development of novel treatments, including multifunctional eye drops for both bacterial keratitis and corneal trauma. Her research findings have important clinical implications, directly informing therapeutic strategies for ocular health. Additionally, Ma’s experience includes publishing scientific articles, with a growing portfolio in well-regarded journals. This combination of clinical knowledge, experimental research, and hands-on technique has allowed her to make valuable contributions to ophthalmic science, particularly in terms of innovative solutions for corneal injury and healing.

Research Focus:

Chunli Ma’s research focus is centered on the mechanistic modulation of corneal injury and wound healing. She investigates the potential of stem cell-derived exosomes in promoting the regeneration of corneal tissues, with a particular interest in their role in reducing scarring after trauma. Her work delves into advanced therapeutic applications, such as multifunctional eye drops containing composite antibacterial and healing properties for the treatment of Pseudomonas aeruginosa keratitis. By targeting the underlying molecular and cellular mechanisms of corneal repair, Ma aims to offer innovative solutions for treating corneal injuries and infections. Her research also explores the impact of wound size and location on the prognosis of penetrating ocular injuries, offering a more nuanced approach to patient care. Chunli’s focus on the development of cutting-edge materials and therapies for ophthalmic applications promises significant advances in clinical practice, particularly for patients with challenging corneal conditions.

Publications Top Notes:

  1. Exosomes derived from adipose mesenchymal stem cells promote corneal injury repair and inhibit the formation of scars by anti-apoptosis 📑🧬
  2. Wound size and location affect the prognosis of penetrating ocular injury 👁️‍🗨️🩹
  3. Potential role of ARG1 c.57G > A variant in Argininemia 🔬🧬

Conclusion:

Chunli Ma’s research reflects an excellent blend of clinical expertise and innovative scientific inquiry. Her work has already made notable contributions to improving the treatment of ocular injuries, particularly in corneal healing and bacterial keratitis. With a clear focus on translational research, she has demonstrated the potential for significant advancements in ophthalmic treatments. Given her ongoing dedication to advancing ophthalmology through novel therapeutic approaches, Chunli Ma is undoubtedly a strong candidate for the Best Researcher Award. With continued growth in her research, collaboration efforts, and scholarly output, she has the potential to make even greater strides in the field of ophthalmology and regenerative medicine.

 

 

 

 

Ping lu | Environment | Best Researcher Award

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Assoc Prof Dr. Ping lu | Environment | Best Researcher Award

Assoc Prof Dr. Ping lu , China university of mining and technology , China

Dr. Ping Lu is an Associate Professor at China University of Mining and Technology, specializing in Environmental Science and Engineering. With a Ph.D. from the University of North Carolina at Charlotte, she has dedicated her career to researching environmental contaminants and their impact on public health. Dr. Lu has authored numerous publications and contributed significantly to the field through innovative research projects focused on pollution prevention, management, and remediation. Her work has led to the development of advanced techniques to combat antibiotic resistance and improve environmental health. An active educator, she teaches core courses to undergraduate and graduate students, emphasizing sustainable development and environmental control.

Publication Profile

Google Scholar

Strengths for the Award

Dr. Ping Lu’s extensive research contributions in environmental science, particularly in the areas of contaminant investigation and remediation, showcase her commitment to safeguarding public health. With a high citation index of 553 and 37 published journals, her work demonstrates significant impact and innovation. Her development of advanced remediation techniques, such as ‘polarity exchange’ electrokinetic remediation, highlights her ability to provide practical solutions to pressing environmental challenges. Additionally, her involvement in high-profile research projects, coupled with her role in educating future scientists, underscores her dedication to both research and teaching.

Areas for Improvement

While Dr. Lu’s research is robust, further engagement with international collaborations could enhance the global impact of her work. Expanding her outreach to diverse research communities may lead to new perspectives and innovative approaches. Additionally, increasing public engagement initiatives could raise awareness of her findings and promote wider adoption of her remediation strategies.

Education 

Dr. Ping Lu holds a Ph.D. in Infrastructure and Environmental Systems from the University of North Carolina at Charlotte, where she developed a strong foundation in environmental research. Prior to that, she earned her Bachelor’s degree in Environmental Science from China University of Mining and Technology (CUMT). Her academic training provided her with the expertise needed to investigate complex environmental issues and design effective remediation strategies. Throughout her career, Dr. Lu has remained committed to advancing her knowledge and skills in environmental science, continually integrating new findings into her teaching and research practices. Her educational journey reflects a profound dedication to addressing environmental challenges and promoting public health through innovative research.

Experience

Dr. Ping Lu has extensive experience in academia and research, currently serving as an Associate Professor in Environmental Science and Engineering at CUMT. Her research portfolio includes numerous projects funded by national and provincial grants, focusing on groundwater pollution, ecological restoration, and contaminant behavior in various environments. Dr. Lu has collaborated with key institutions, including the CDC, to enhance her research’s practical implications. Additionally, she has served on editorial boards, contributing to the dissemination of vital research findings. With a citation index of 553 and over 37 published journals, her work has significantly influenced the field. Dr. Lu also engages in consultancy projects, providing her expertise to industries seeking sustainable practices. Through teaching and mentorship, she has inspired the next generation of environmental scientists, fostering a culture of innovation and dedication within her department.

Research Focus 

Dr. Ping Lu’s research primarily delves into environmental contaminants, their behavior, and innovative remediation techniques. Her work is centered on understanding the processes governing the migration and proliferation of antibiotic-resistant microorganisms and pathogenic contaminants. She has developed cost-effective treatment methods, including ‘polarity exchange’ electrokinetic remediation and advanced mesoporous materials synthesis, to combat environmental pollution effectively. Dr. Lu’s investigations address critical issues in groundwater pollution, contaminant removal, and public health safeguarding. Her ongoing projects include studying Cryptosporidium transmission in sewage treatment plants and exploring the acid-generating mechanisms in coal mining areas. By combining theoretical insights with practical applications, Dr. Lu aims to provide sustainable solutions for environmental health challenges, contributing to the broader understanding of contamination processes and their regulatory implications.

Publication Top Notes

  1. Electrokinetic remediation of chromium-and cadmium-contaminated soil from abandoned industrial site 🌍
  2. Impact factors of the accumulation, migration and spread of antibiotic resistance in the environment 🔬
  3. Environmental cumulative effects of coal underground mining ⛏️
  4. Main challenges of closed/abandoned coal mine resource utilization in China 🇨🇳
  5. Degradation mechanisms of cefotaxime using biochar supported Co/Fe bimetallic nanoparticles 🌱
  6. Enhanced phenanthrene removal in aqueous solution using modified biochar supported nano zero-valent iron 💧
  7. Distribution and bioavailability of metals in subsidence land in a coal mine China ⚖️
  8. Removals of cryptosporidium parvum oocysts from swimming pool water by diatomaceous earth filtration 🏊‍♀️
  9. Review of antibiotic pollution in the seven watersheds in China 📚
  10. Review of swimming-associated cryptosporidiosis and Cryptosporidium oocysts removals from swimming pools 🦠
  11. A pilot-scale study of Cryptosporidium-sized microsphere removals from swimming pools via sand filtration 🧪
  12. Cryptosporidium Contamination and Attributed Risks in Yunlong Lake in Xuzhou, China 🚰
  13. Synthesis of amino-functionalized mesoporous materials with environmentally friendly surfactants 🌿
  14. Low impact development design for urban stormwater management-a case study in USA 🇺🇸
  15. Environmental concerns of shale gas production in China 🌐
  16. A full-scale study of Cryptosporidium parvum oocyst removals from swimming pools via sand filtration 🏖️
  17. Improvement in electrokinetic remediation of chromium contaminated soil with polarity exchange technique ⚡
  18. Removal of sulfonamide resistance genes in fishery reclamation mining subsidence area by zeolite 🧬
  19. Distribution of antibiotic resistance genes and microbial communities in a fishery reclamation mining subsidence area 📊
  20. Controlling factors of shortcut nitrification in sequencing batch reactor 🔄

Conclusion

In conclusion, Dr. Ping Lu is an exemplary candidate for the Best Researcher Award. Her innovative contributions to environmental science and public health, combined with her teaching dedication, position her as a leader in her field. With opportunities for further collaboration and outreach, her future research could yield even greater impacts on global environmental health challenges.