ALINE TAKEJIMA | Tissue engineering | Women Researcher Award

Published on by Cell Biologist

Dr. ALINE TAKEJIMA | tissue engineering | Women Researcher Award

Dr. ALINE TAKEJIMA, pontificia universidade catolica do parana, Brazil

Dr. Aline Luri Takejima is a physician-scientist from Brazil, specializing in regenerative medicine and wound healing. She holds an MD and a PhD in Health Sciences from the Pontifical Catholic University of Paraná (PUCPR), where she currently conducts postdoctoral research. With a focus on biological therapies involving the amniotic membrane, Wharton’s jelly, and mononuclear stem cells, Dr. Takejima has published in multiple high-impact scientific journals. Her research aims to develop novel regenerative strategies to treat complex wounds and enhance tissue repair. As an active member of PUCPR’s Wound Healing Research Group and the Brazilian Society of Plastic Surgery, she combines scientific rigor with clinical insight to bridge bench-to-bedside innovation. Her academic contributions are guided by a translational approach, offering promising avenues for future clinical applications in tissue engineering.

Publication Profile: 

Orcid

✅ Strengths for the Award:

  1. Focused Research Excellence:
    Dr. Takejima’s work on biological scaffolds and stem cells in wound healing is both innovative and clinically relevant. Her studies using amniotic membrane, Wharton’s jelly, and bone marrow mononuclear cells show promising regenerative outcomes in preclinical models.

  2. Research Productivity:
    With 9 peer-reviewed journal articles in high-quality platforms (e.g., Biomedicines, Tissue Barriers, Annals of Biomedical Engineering), she demonstrates consistent academic output in her field.

  3. Translational Impact:
    Her research bridges basic science and clinical practice, aiming to provide regenerative solutions for patients with chronic wounds and cardiac damage.

  4. Collaborative Engagement:
    Active participation in a multidisciplinary wound healing research group, contributing to cross-functional scientific advancements.

  5. Recognition Potential:
    As a young, emerging woman researcher in biomedical sciences, she stands as a role model for future female scientists in Latin America and beyond.

🔧 Areas for Improvement:

  1. Intellectual Property & Innovation:
    No patents filed yet; transitioning her research into patentable therapies or commercial applications would increase its societal and economic impact.

  2. Leadership Roles:
    While active in research, taking on editorial or scientific leadership positions would enhance her academic visibility and influence.

  3. Internationalization:
    She would benefit from developing international collaborations or fellowships to diversify her research scope and increase global reach.

  4. Industry Engagement:
    Engaging in consultancy or biotech partnerships can further the translational impact of her regenerative strategies.

🎓 Education:

Dr. Takejima’s educational journey began with a Doctor of Medicine (MD) degree from the Pontifical Catholic University of Paraná (PUCPR), Brazil. Her passion for research led her to pursue a Doctorate (PhD) in Health Sciences/Medicine, also at PUCPR. Her doctoral thesis focused on the use of biologically active materials such as the amniotic membrane and stem cells to enhance wound healing. Throughout her academic training, she demonstrated a strong commitment to translational medicine by integrating basic science with clinical practice. During her PhD, she engaged in experimental models involving stem cell therapy and tissue engineering, which laid the groundwork for her current postdoctoral research. Her educational path reflects both depth and specialization in the biomedical sciences, particularly in regenerative medicine and cellular therapies.

💼 Experience:

Dr. Aline Takejima has over a decade of experience in medical and scientific fields, balancing her role as a physician with that of a postdoctoral researcher. Her clinical background informs her research, particularly in areas of wound healing and regenerative medicine. At PUCPR, she contributes to the Wound Healing Research Group, where she is involved in designing and conducting animal model studies to test the effects of biomaterials and stem cells. Her multidisciplinary research integrates immunology, histopathology, and molecular biology. With nine peer-reviewed publications and participation in collaborative research, she has become a respected contributor to the field. Though early in her research career, her trajectory shows a steady rise, marked by evidence-based outcomes and a commitment to innovation. Her goal is to bridge clinical challenges with regenerative solutions that can be implemented in real-world medical practice.

🔬 Research Focus:

Dr. Takejima’s research focuses on regenerative strategies for wound healing, utilizing biomaterials and stem cells. Her work primarily explores the application of amniotic membrane, Wharton’s jelly, and bone marrow-derived mononuclear stem cells in treating complex or chronic skin wounds. Using experimental models in rats and rabbits, she evaluates histological recovery, inflammation modulation, and tissue regeneration. A significant aspect of her research is understanding how these materials promote healing through paracrine effects rather than direct integration, offering a safer and scalable pathway to clinical application. Additionally, her work extends to cardiac and tracheal tissue repair, emphasizing the versatility of these regenerative approaches. The translational nature of her research bridges laboratory discoveries with potential bedside applications, positioning her at the forefront of cellular therapy and biomaterials science.

📚 Publications Top Notes:

  1. 🧠 Wharton’s Jelly Bioscaffolds Improve Cardiac Repair with Bone Marrow Mononuclear Stem Cells in Rats – Journal of Functional Biomaterials, 2025

  2. 🧫 The effects of decellularized amniotic membrane and Wharton’s jelly on the healing of experimental skin wounds in rats – Tissue Barriers, 2025

  3. ❤️ Bone-marrow mononuclear cells and acellular human amniotic membrane improve global cardiac function… – Anais da Academia Brasileira de Ciências, 2024

  4. 🫁 Tracheal regeneration with acellular human amniotic membrane and 15d-PGJ2 nanoparticles in rabbits – Anais da Academia Brasileira de Ciências, 2023

  5. 🧬 Acellular Biomaterials + Autologous Stem Cells Improve Wound Healing via Paracrine Effects – Biomedicines, 2023

  6. 💉 Decellularized Amniotic Membrane Solubilized with Hyaluronic Acid in Wound Healing – Annals of Biomedical Engineering, 2022

  7. 🧪 Role of Mononuclear Stem Cells and Decellularized Amniotic Membrane in Skin Wounds – Tissue Barriers, 2022

  8. 🏥 Trauma hepático: epidemiologia de cinco anos… – Revista do Colégio Brasileiro de Cirurgiões, 2008

🧾 Conclusion:

Dr. Aline Luri Takejima is an outstanding candidate for the Women Researcher Award. Her academic profile demonstrates a strong foundation in regenerative medicine with significant contributions to wound healing research. Her commitment to applying biological therapies in clinical contexts shows both depth and innovation. As a woman scientist in a competitive field, she exemplifies leadership, dedication, and potential. With further growth in global engagement and innovation strategy, Dr. Takejima is poised to become a future leader in regenerative biomedical research.

Amira Ibrahim | Cell Differentiation Processes | Innovative Research Award

Published on by Cell Biologist

Dr. Amira Ibrahim | Cell Differentiation Processes | Innovative Research Award

Dr. Amira Ibrahim , Egyptian Atomic Energy Authority , Egypt

Dr. Amira Ibrahim Sayed is a dedicated academic and researcher, currently serving as a Lecturer at the National Center for Radiation Research and Technology, Atomic Energy Authority, Egypt. With a career grounded in oral medicine and radiology, Dr. Sayed demonstrates a multidisciplinary approach by integrating dental science with radiological and pharmaceutical research. She is known for her strong commitment to advancing healthcare through both education and scientific inquiry. Her diverse academic and professional background allows her to bridge the gap between clinical practice and biomedical research. Passionate about mentoring and teaching, she holds part-time academic roles at Misr University for Science and Technology. Dr. Sayed’s collaborative work in the synthesis of novel therapeutic agents highlights her innovative spirit and significant contributions to drug discovery, antiviral therapy, and radiation impact studies. Her impressive portfolio of peer-reviewed publications and participation in key academic courses make her a well-rounded candidate for the Research for Innovative Research Award.

Publication Profile: 

Google Scholar

✅ Strengths for the Award:

  1. Interdisciplinary Research Excellence
    Dr. Sayed merges expertise in oral medicine, radiology, and pharmaceutical chemistry—a rare and impactful blend. Her research spans both clinical and molecular levels, showing depth and versatility.

  2. Strong Publication Record
    With over 10 peer-reviewed publications in high-impact journals, her work is recognized across multiple fields including medicinal chemistry, antiviral therapy, and radiation sciences.

  3. Innovative Drug Discovery Focus
    Her work on the synthesis and molecular docking of pyrrolopyrimidine, benzimidazole, and thiouracil derivatives demonstrates cutting-edge innovation in developing novel therapeutic agents.

  4. Experience in Radiation Health Research
    Given her role at the National Center for Radiation Research & Technology, she actively contributes to important national research in radiation biology—an area of growing relevance.

  5. Academic and Educational Contributions
    As a lecturer at multiple institutions, she plays a vital role in knowledge transfer, student mentorship, and academic development.

  6. Multilingual Communication & Skills
    Her ability to communicate in Arabic, English, and basic German supports her involvement in international collaborations.

🛠 Areas for Improvement:

  1. Global Research Collaborations
    Greater participation in international collaborative projects, consortia, or funding initiatives would further elevate her impact and visibility.

  2. Patents and Practical Applications
    Filing for patents or translating her synthesized compounds into preclinical or clinical studies could reinforce the practical significance of her innovations.

  3. Increased Leadership Roles
    Engagement in leading research teams or coordinating large-scale projects could reflect greater influence within her scientific community.

🎓 Education:

Dr. Amira Ibrahim Sayed began her academic journey with a Bachelor’s degree in Dental Surgery (B.D.S) in 2005 from the Faculty of Oral and Dental Medicine, Cairo University. She further specialized in Oral Radiology, obtaining a Master of Science (M.Sc.) in 2014 from the same institution. Her academic curiosity and passion for interdisciplinary research led her to pursue a Ph.D. in Oral Medicine, Periodontology, Oral Diagnosis, and Radiology, which she completed in 2020 at Al-Azhar University. This diverse academic foundation has enabled her to explore the intersections of radiology, oral health, and medicinal chemistry. Dr. Sayed’s education reflects a strong emphasis on both clinical and scientific research skills, providing her with the expertise required to innovate in both diagnostic and therapeutic fields. Her comprehensive academic background makes her uniquely equipped to contribute to scientific research in radiation biology, oral diagnostics, and pharmaceutical innovation.

🧪 Experience:

Dr. Amira Ibrahim Sayed has amassed extensive academic and research experience, notably as a Lecturer at the National Center for Radiation Research & Technology, Atomic Energy Authority, since 2021. She started her professional journey there in 2015 as an Assistant Lecturer. Additionally, she contributes to higher education as a part-time Lecturer at Misr University for Science and Technology, where she also held an Assistant Lecturer role between 2015 and 2016. Her responsibilities include curriculum development, supervising student research, and lecturing in oral medicine and radiology. She has also actively participated in specialized training, such as the Ionizing Radiation Protection course, enhancing her qualifications in radiological safety. Her hands-on experience in both academic and applied research settings, combined with her interdisciplinary work in pharmacology and medical imaging, highlights her competence in navigating complex scientific challenges. Her professional trajectory is a testament to her adaptability, diligence, and commitment to innovation in health sciences.

🔬 Research Focus:

Dr. Amira Ibrahim Sayed’s research is centered around oral radiology, radiation protection, and the synthesis of novel pharmaceutical agents with therapeutic potential. Her interdisciplinary work bridges oral health sciences with medicinal chemistry, aiming to improve diagnostics and treatments in fields such as oncology, virology, and inflammation. She has explored the biological effects of magnetic resonance imaging and radiation on dental restorations and bone healing, highlighting her commitment to clinical relevance. Moreover, her innovative research on pyrrolopyrimidine and benzimidazole derivatives positions her at the forefront of drug discovery, particularly in antiviral, antifungal, and anti-inflammatory domains. Dr. Sayed utilizes molecular docking and simulation techniques to predict compound efficacy and mechanism of action. Her dedication to enhancing patient care through translational research, combined with a strong publication record in peer-reviewed journals, showcases her as a forward-thinking scientist making meaningful contributions to biomedical innovation.

📚 Publications Top Notes:

  1. 🧲 Effect of Magnetic Resonance Imaging on Microleakage of Amalgam Restoration

  2. 🦴 Radiographic and Histopathologic Evaluation of L-Carnitine and Vitamin E Efficacy on Irradiated Jaw Bones

  3. 🧪 Synthesis of Certain Pyrimidine Derivatives as Antimicrobial and Anti-inflammatory Agents

  4. 🧬 Design, Synthesis, and Molecular Docking of Pyrrolopyrimidine Derivatives as NS5B Polymerase Inhibitors

  5. 🦠 Novel Antiviral Compounds Against Gastroenteric Viral Infections

  6. 🧫 Synthesis of Novel Pyrroles and Fused Pyrroles as Antifungal and Antibacterial Agents

  7. 💊 Synthesis Strategies and Biological Value of Pyrrole and Pyrrolopyrimidine

  8. 🧯 Design and Evaluation of Pyrrolopyrimidine Derivatives as Antioxidant and Anti-inflammatory Agents

  9. 🦠 Evaluation of Pyrrolopyrimidine Derivatives as Antivirals Against Gastroenteric Viruses

📝 Conclusion:

Dr. Amira Ibrahim Sayed is a highly suitable candidate for the Research for Innovative Research Award. Her commitment to interdisciplinary innovation, particularly in radiation research and therapeutic compound development, aligns well with the award’s objective to honor groundbreaking scientific contributions. With a strong track record of impactful publications and academic leadership, she stands out as a researcher dedicated to improving health outcomes through science. Strengthening her global collaborations and translating research into applications will only further her potential for scientific excellence and recognition.