Eunmiri Roh | Molecular Mechanisms Signaling | Best Researcher Award

Prof. Eunmiri Roh | Molecular Mechanisms Signaling | Best Researcher Award

Prof. Eunmiri Roh, Department of Cosmetic Science, Kwangju Women’s University, South Korea

Dr. Eunmiri Roh is an accomplished biomedical scientist and Assistant Professor in the Department of Cosmetic Science at Kwangju Women’s University, Republic of Korea. With a strong foundation in microbiology and pharmaceutical sciences, Dr. Roh has established herself in the field of skin cancer biology and cosmetic science. Her research explores cellular and molecular pathways in skin carcinogenesis, melanogenesis, photoaging, and chemoprevention, emphasizing UV-induced damage and pigmentation disorders. She has published extensively in top-tier international journals and has collaborated with leading institutions, including the University of Minnesota. Dr. Roh’s dedication to integrating science with practical beauty and health solutions positions her as a leading figure in her field. Her exceptional contributions have earned her multiple research honors, and she continues to innovate at the intersection of pharmaceutical science and cosmetology.

Publication Profile:

Google Scholar

Orcid

✅ Strengths for the Award:

  1. High-Impact Research Portfolio
    Dr. Roh has produced a consistent stream of peer-reviewed publications in high-impact international journals, such as Biochemical Pharmacology, Cancer Research, Journal of Investigative Dermatology, and Cells, reflecting her solid global research presence.

  2. Focused and Societally Relevant Research
    Her primary focus—UV-induced skin carcinogenesis, pigmentation disorders, and chemoprevention—addresses pressing issues in dermatology and cosmetic health, aligning with public health interests and the cosmetic industry’s innovation goals.

  3. Interdisciplinary Expertise
    Dr. Roh’s training in biochemistry, pharmacy, and microbiology supports a multidisciplinary research approach, which is evident in her collaboration with dermatologists, chemists, and pharmacologists.

  4. Award-Winning Excellence
    She has earned multiple national and international research awards, including from the Korean Society of Microbiology and Biotechnology, the Korean Society of Cancer Prevention, and The Hormel Institute (USA), validating her scientific merit.

  5. Strong International Collaboration
    Collaboration with globally recognized institutions like the University of Minnesota and The Hormel Institute reflects the international relevance and applicability of her research.

  6. Translational Research Impact
    Dr. Roh’s research bridges basic science and application—discovering bioactives for cosmetics and drug delivery systems, highlighting practical impact in dermatology and consumer health.

⚙️ Areas for Improvement:

  1. Leadership in Independent Grants
    While publication output is impressive, securing independent competitive research funding (e.g., national research grants, PI-led international projects) would further reinforce her research leadership.

  2. Mentorship and Academic Development
    Enhanced documentation of her mentorship role—particularly training graduate students, Ph.D. candidates, or postdoctoral researchers—would highlight her academic influence beyond publications.

  3. Commercial Translation or Patents
    Filing patents or commercializing products/formulations related to her discoveries (e.g., natural anti-pigmentation agents or UV protectants) could amplify her impact and innovation metrics.

  4. Greater Engagement in Scientific Leadership
    Increased visibility in scientific committees, editorial boards, or as a conference keynote speaker would establish her as a thought leader in her field.

📘 Education:

Dr. Roh’s academic journey began with a Bachelor of Science in Microbiology from the College of Natural Sciences at Chungbuk National University (2007). Motivated to delve deeper into biomedical research, she pursued her Master’s degree in Life Pharmacy (2009), followed by a Ph.D. in Pharmaceutical Function with a focus on biochemistry (2012) at the College of Pharmacy in the same university. Her graduate and doctoral training provided her with a robust understanding of molecular biology, pharmacology, and biochemical mechanisms, forming the backbone of her current work in dermatological science and cosmetic pharmacology. The interdisciplinary nature of her studies laid the groundwork for her specialization in skin biology, UV-induced skin damage, and pigmentation-related drug discovery. Her academic foundation is both broad and deep, equipping her with the necessary tools to explore innovative solutions for skin health through cosmetic science.

🧪 Experience:

Dr. Eunmiri Roh currently serves as an Assistant Professor at the Department of Cosmetic Science, Kwangju Women’s University, where she leads research on cosmetic pharmacology, focusing on skin cancer prevention and pigmentation disorders. Before joining academia, she gained valuable research experience at globally recognized institutions such as The Hormel Institute, University of Minnesota, where she was awarded for outstanding scientific contributions. She has collaborated in multidisciplinary teams working on skin photoaging, UV protection, anti-inflammatory pathways, and novel cosmetic drug formulations. Her work spans in vitro and in vivo studies, biochemical analysis, and formulation science. Dr. Roh also contributes to educational excellence, guiding undergraduate and graduate students in research methodologies and scientific writing. Her blend of practical, clinical, and research experience strengthens her impact in both the cosmetic and biomedical sectors. She is known for her rigorous scientific approach and her drive to translate laboratory findings into real-world applications.

🏅 Awards and Honors:

Dr. Roh has received numerous accolades for her pioneering research in molecular pharmacology and cosmetic science. She was honored with the Outstanding Poster Presentation Award from the Korean Society of Microbiology and Biotechnology in June 2022, recognizing her innovative insights into skin-related biochemical mechanisms. Similarly, she earned the Outstanding Poster Presentation Award from the Korean Society of Cancer Prevention in November 2021 for her work on chemopreventive agents. Earlier, in 2019, she received the Summer Research Retreat Award (2nd place) from The Hormel Institute, University of Minnesota—an acknowledgment of her collaborative contributions to cancer biology. These awards underscore her reputation for research excellence, innovation, and dedication to advancing the fields of dermatology and cosmetology. Her consistent recognition at both national and international levels reflects her commitment to impactful science and her growing influence in molecular dermatology and cosmetic formulation research.

🔬 Research Focus:

Dr. Roh’s research primarily focuses on molecular and cellular targets involved in carcinogenesis, skin aging, and pigmentation. Her studies aim to understand the biochemical pathways influenced by solar UV radiation, and their role in inducing skin cancer and photoaging. She also explores mechanisms of melanogenesis, contributing to the discovery of anti-hyperpigmentation agents. A distinctive element of her work is the translation of pharmacological findings into cosmetic applications, bridging the gap between biochemistry and skincare innovation. Her recent work includes green tea polyphenols, sesame glycoproteins, and natural bioactives for UV protection. She also investigates novel formulations for transdermal drug delivery and anti-inflammatory responses in skin cells. Her holistic approach encompasses in vitro, in vivo, and 3D skin models, emphasizing both efficacy and safety. Her contributions are instrumental in developing scientifically validated cosmetics and preventive strategies against UV-induced damage and pigment disorders.

📚 Publications Top Notes:

  1. 🧴 Evaluation and analysis of major competency achievement in beauty and cosmetics students – J Korean Soc Cosmetol (2024)

  2. 🌿 Protective Effects of Sesame Glycoproteins on UV-Induced Skin Aging – Pharmaceuticals (2024)

  3. ☀️ Orobol suppresses development of cutaneous SCC – Biochem Pharmacol (2023)

  4. 💊 Topical Rocuronium Bromide Formulation for Skin Delivery – Int J Mol Sci (2023)

  5. 🧪 Higenamine reduces fine-dust-induced MMP-1 in keratinocytes – Plants (2023)

  6. 🔥 Targeting IKKβ in acetaminophen-induced hepatotoxicity – Pharmaceutics (2023)

  7. 🌸 Lotusine inhibits UV-induced MMP-1 – Plants (2022)

  8. 🔍 Structural basis of multifunctional roles of Ints3 C-terminal domain – J Biol Chem (2021)

  9. 🧬 GSK3β and WT1 in tumor progression – Cancer Res (2021)

  10. 🌞 Effectiveness of FDA-approved sunscreens against UV damage – Cells (2020)

🔚 Conclusion:

Dr. Eunmiri Roh is a highly qualified and outstanding researcher whose scientific contributions to dermatological pharmacology, cosmetic biochemistry, and skin health are both innovative and impactful. Her robust publication record, research awards, and international collaborations indicate that she is well-positioned to receive recognition such as the Best Researcher Award. With minor enhancements in grant leadership, mentorship roles, and translational outcomes, her academic profile could rise even further.

Nabil Alshurafa | Molecular Mechanisms Signaling | Best Researcher Award

Prof. Nabil Alshurafa | Molecular Mechanisms Signaling | Best Researcher Award

Prof. Nabil Alshurafa, Northwestern University, United States

Dr. Nabil Alshurafa is a tenured Associate Professor at Northwestern University’s Feinberg School of Medicine in the Department of Preventive Medicine. A recognized expert in wearable health technology and artificial intelligence, his work bridges computer science and preventive health. With a strong foundation in AI, embedded systems, and wireless health, Dr. Alshurafa is known for pioneering research that transforms how chronic conditions are monitored remotely. He has held prestigious fellowships, serves on influential editorial boards, and contributes actively to global conferences. Passionate about advancing digital health, his interdisciplinary approach fosters innovation in non-invasive health monitoring technologies. His body of work, including over 100 peer-reviewed publications and several with high citation metrics, has significantly shaped mobile and wearable health sensing technologies. Known for collaborative leadership and visionary research, he continues to inspire advancements in AI-driven healthcare.

Publication Profile: 

Google Scholar

✅ Strengths for the Award:

  1. Innovative Research Focus:
    Dr. Alshurafa is a pioneer in AI-powered wearable health technologies, focusing on practical, non-invasive solutions for chronic disease management, nutrition monitoring, and human activity recognition.

  2. High-Impact Publications:
    His publications are well-cited, including several landmark works like “Deep learning in human activity recognition…” and “NeckSense…” that demonstrate translational value in digital health and mobile sensing.

  3. Prestigious Roles & Affiliations:
    Editorial roles with ACM IMWUT, IEEE, and Nature Digital Medicine, along with organizational roles in IEEE PerCom, underscore his peer recognition and leadership in the field.

  4. Award-Winning Work:
    His research has received Best Paper Awards and has been presented at highly selective conferences with acceptance rates as low as 10–25%.

  5. Interdisciplinary Impact:
    His work intersects computer science, biomedical engineering, and preventive medicine, which is critical in tackling modern healthcare challenges through integrated technology.

  6. Real-World Applications:
    Tools like WANDA, NeckSense, and smart bedsheets reflect direct applicability to patient care and wellness monitoring.

🔧 Areas for Improvement:

  1. Global Visibility:
    While his national recognition is strong, increasing presence in international healthcare policy and standards bodies could elevate his global influence.

  2. Cross-Sector Translation:
    Although academically impactful, more visible industry collaborations or commercial deployments (e.g., FDA-approved products or spin-offs) would enhance the translational credibility of his work.

  3. Public Engagement:
    Expanding outreach through public talks, tech-for-health summits, or popular science channels would help bring his innovations closer to everyday users and clinicians.

  4. Broader Health Diversity Applications:
    More research could be targeted toward underserved populations or global health settings, showcasing scalability and equity of the solutions.

🎓 Education:

Dr. Nabil Alshurafa began his academic journey at the University of California, Los Angeles (UCLA), earning a Bachelor of Science in Computer Science in 2003 with summa cum laude honors. He further pursued graduate education at UCLA, receiving his Master of Science in Computer Science in 2010 with a specialization in Artificial Intelligence. His graduate work laid the foundation for his future contributions in AI-powered healthcare. To gain applied research experience, he joined UCLA’s Wireless Health Institute from 2013 to 2015 as a Wireless Health Fellow. This multidisciplinary training equipped him with expertise in sensor technology, machine learning, and biomedical systems. The academic rigor and technological immersion at UCLA played a pivotal role in shaping his research direction—particularly in remote health monitoring and ubiquitous computing, which have become the hallmarks of his career.

🧪 Experience:

Dr. Alshurafa’s career spans academia, research, and editorial leadership. Since 2022, he has served as a tenured Associate Professor at Northwestern University, where he leads innovative projects in wearable computing and health analytics. His prior fellowship at UCLA’s Wireless Health Institute (2013–2015) was instrumental in honing his applied skills in biomedical sensing and embedded AI systems. He has contributed to multiple high-impact research studies, demonstrating leadership in both collaborative and solo research environments. Beyond teaching and mentoring, Dr. Alshurafa plays a key role in global health informatics networks, serving on editorial boards such as ACM IMWUT, PLOS ONE, and Nature Digital Medicine. His industry engagement is evident from his organizational roles at IEEE PerCom, where he has served as Industry Track Chair and Sponsorship Chair. These roles reflect his commitment to bridging academia with real-world technological solutions in preventive and mobile health.

🏅 Awards and Honors:

Dr. Alshurafa has been recognized for his academic excellence and leadership in health informatics. He is a member of ACM and has held key editorial positions in ACM Interactive, Mobile, Wearable, and Ubiquitous Computing (IMWUT). His roles with IEEE PerCom as Industry Track Chair (2018) and Sponsorship Chair (2019) highlight his prominence in mobile health computing communities. His research has been distinguished with honors such as Best Paper Award at the IEEE International Conference on Wearable and Implantable Body Sensor Networks (BSN). Additionally, several of his publications have been widely cited, underscoring his influence in the field. His editorial board memberships across journals like PLOS ONE, IEEE Biomedical Health Informatics, and Nature Digital Medicine showcase peer recognition of his expertise. Collectively, these accolades reflect a sustained and impactful contribution to health technologies and interdisciplinary research.

🔬 Research Focus:

Dr. Nabil Alshurafa’s research centers on AI-driven wearable technologies for remote health monitoring and behavioral health sensing. He focuses on building unobtrusive, sensor-based systems that can track physiological signals and behaviors such as eating, physical activity, and sleep in real-world environments. By integrating machine learning with low-power embedded systems, he develops scalable tools for chronic disease management, including heart failure and diabetes. His work leverages signal processing, stochastic modeling, and deep learning to transform raw sensor data into clinically actionable insights. A key contribution is his development of NeckSense, a multi-sensor necklace for detecting eating behaviors, and WANDA, an end-to-end health monitoring system. Through interdisciplinary collaborations, he also explores nutrition sensing, exergaming, and rehabilitation technologies. His ultimate goal is to enable proactive, personalized healthcare solutions that reduce the burden on patients and providers alike while enhancing wellness through smart, wearable ecosystems.

📚 Publications Top Notes: 

  1. 🕷️ Artificial Spider: Eight-legged arachnid and autonomous learning of locomotion

  2. ❤️ WANDA: An end-to-end remote health monitoring and analytics system for heart failure patients

  3. 🔋 Opportunistic hierarchical classification for power optimization in wearable movement monitoring systems

  4. 🩺 Dynamic task optimization in remote diabetes monitoring systems

  5. 😴 Inconspicuous on-bed respiratory rate monitoring

  6. 🛏️ A dense pressure sensitive bedsheet design for unobtrusive sleep posture monitoring

  7. 👕 Improving accuracy in E-Textiles as a platform for pervasive sensing

  8. 🚶 Robust human intensity-varying activity recognition using Stochastic Approximation in wearable sensors

  9. 🏋️ On-bed monitoring for range of motion exercises with a pressure sensitive bedsheet

  10. 🎮 MET calculations from on-body accelerometers for exergaming movements

🧾 Conclusion:

Dr. Nabil Alshurafa stands out as an exceptionally qualified candidate for the Best Researcher Award. His work embodies the intersection of innovation, application, and societal benefit. He has demonstrated leadership in both research productivity and community contribution, with a track record that is not only prolific but also highly relevant to the future of preventive and digital healthcare. His pioneering systems in wearable health monitoring have the potential to transform how health is tracked and managed in real time, offering personalized insights and clinical utility.

Haiping Zhang | Signal Transduction Mechanisms | Best Researcher Award

Prof. Haiping Zhang | Signal Transduction Mechanisms | Best Researcher Award

Prof. Haiping Zhang, anhui agricultural university, China

Prof. Haiping Zhang is a distinguished plant molecular biologist at the College of Agronomy, Anhui Agricultural University, China. He is affiliated with the Key Laboratory of Wheat Biology and Genetic Improvement on Southern Yellow & Huai River Valley, under the Ministry of Agriculture and Rural Affairs. With a strong focus on improving wheat productivity and resilience, Prof. Zhang has made significant contributions to understanding gene regulation mechanisms in seed dormancy, germination, and yield traits. His recent work investigates transcription factors and their impact on hormone biosynthesis, especially gibberellin and ethylene signaling. Widely published in high-impact journals, his research stands at the intersection of molecular genetics and applied agronomy, aiming to develop cultivars with improved yield stability and adaptability. Prof. Zhang is recognized for his leadership in collaborative research and his commitment to training young scientists in advanced genetic and biotechnological tools for sustainable wheat improvement.

Publication Profile: 

Scopus

Strengths for the Award:

  1. 🔬 High-Impact Research in Wheat Genetics
    Prof. Zhang’s research addresses essential topics in crop science, particularly seed dormancy and gibberellin regulation, which are critical for yield stability and pre-harvest sprouting resistance in wheat. His studies contribute directly to improving food security and crop resilience.

  2. 📚 Recent Publications in Reputed Journals
    In 2024–2025, he has published in prestigious, peer-reviewed journals such as:

    • International Journal of Biological Macromolecules

    • Environmental and Experimental Botany

    • BMC Plant Biology
      These are respected outlets for plant biology and biotechnology research.

  3. 🎯 Focused and Coherent Research Theme
    His work follows a consistent and meaningful trajectory, exploring transcription factors (e.g., TaERF-2A, TaNAC018-7D) and their regulation of GA biosynthesis genes, directly tied to agronomically important traits.

  4. 🧩 Integrative Methodology
    Prof. Zhang uses an integrative approach, combining molecular biology, genomics (e.g., GWAS), and functional gene analysis to achieve both mechanistic insights and breeding applications.

  5. 🇨🇳 National Importance and Institutional Role
    As a professor at a leading Chinese agricultural university and a core contributor to a Ministry of Agriculture Key Laboratory, his research has both scientific and policy-level relevance in China.

⚙️ Areas for Improvement:

  1. 🌍 Broader International Collaboration
    While his work is impactful, future projects could benefit from expanding global collaborations—particularly with wheat research groups in North America, Europe, and South Asia—to raise visibility and enable joint innovation.

  2. 📣 Visibility and Science Communication
    Prof. Zhang could enhance his global research profile by:

    • Presenting at international conferences

    • Engaging in more open science or outreach platforms

    • Publishing review articles or perspective pieces

  3. 📊 Citations and Impact Tracking
    As the current papers have 0 citations (likely due to recency), tracking future impact (via citation metrics or media attention) will further support long-term recognition.

🎓 Education:

Prof. Haiping Zhang earned his undergraduate degree in Agronomy from Anhui Agricultural University, laying a solid foundation in crop sciences and plant physiology. He pursued his Master’s in Crop Genetics and Breeding, where he developed a keen interest in molecular plant biology. Driven by curiosity in genetic regulation, he obtained a Ph.D. in Plant Molecular Genetics, focusing on hormone signaling and gene expression in cereal crops. His doctoral research emphasized gene-function analysis related to stress tolerance and developmental pathways. To deepen his expertise, Prof. Zhang has also participated in national and international training programs, including advanced workshops in genome editing, transcriptomics, and plant phenotyping. His academic journey reflects a deep commitment to interdisciplinary learning, combining classical breeding principles with cutting-edge molecular tools. This strong educational background has equipped him with the knowledge and skills to tackle complex challenges in wheat improvement and to lead high-impact research projects across China and beyond.

🧪 Experience:

Prof. Haiping Zhang currently serves as a senior professor and principal investigator at the College of Agronomy, Anhui Agricultural University. With over 20 years of experience in plant science, he has led numerous research projects funded by the Chinese Ministry of Agriculture and the National Natural Science Foundation. He is a core member of the Key Laboratory of Wheat Biology and Genetic Improvement, where he mentors graduate students and postdocs in functional genomics and molecular breeding. Prof. Zhang’s expertise spans transcription factor analysis, gene editing (e.g., CRISPR/Cas), and genome-wide association studies (GWAS). He actively collaborates with national wheat breeding centers and has served on editorial boards of agricultural science journals. He is frequently invited as a reviewer and speaker at plant biotechnology conferences. His professional experience reflects a rare blend of teaching, research, and applied innovation in one of the world’s most critical food crops—wheat.

🔬 Research Focus:

Prof. Haiping Zhang’s research centers on molecular regulation of seed dormancy, germination, and yield traits in wheat, with a strong emphasis on plant hormone biosynthesis and transcription factor networks. His work integrates ethylene- and gibberellin-responsive gene pathways to elucidate the mechanisms by which specific genes such as TaGA2ox2-3B and TaGA7ox-A1 influence critical agronomic traits. Prof. Zhang applies advanced tools such as RNA-seq, CRISPR gene editing, and GWAS to dissect regulatory pathways at the genomic level. He also focuses on identifying key genetic variants associated with desirable traits across diverse wheat populations. His aim is to provide molecular targets for wheat breeders seeking to enhance seed viability, resistance to pre-harvest sprouting, and yield stability under varying environmental conditions. By linking basic gene function with applied breeding, his research contributes to China’s national food security strategy and offers global relevance in sustainable crop improvement.

📚 Publication Top Notes:

  1. 📘 The ethylene responsive factor TaERF-2A activates gibberellin 2-oxidase gene TaGA2ox2-3B expression to enhance seed dormancy in wheatInternational Journal of Biological Macromolecules, 2025

  2. 🌱 A wheat NAC transcription factor, TaNAC018-7D, regulates seed dormancy and germination by binding to the GA biosynthesis gene TaGA7ox-A1Environmental and Experimental Botany, 2025

  3. 🌾 Single- and multi-locus genome-wide association study reveals genomic regions of thirteen yield-related traits in common wheatBMC Plant Biology, 2024

🔚 Conclusion:

Prof. Haiping Zhang is a highly suitable candidate for the Best Researcher Award. His research is timely, targeted, and methodologically sound—addressing key genetic levers for wheat yield and dormancy control. His publications reflect scientific maturity and innovation, and his institutional role enhances his national significance. With expanded outreach and collaborations, his influence could grow further, both in China and internationally.

Wei Zhang | Signal Transduction Mechanisms | Best Researcher Award

Prof. Dr. Wei Zhang | Signal Transduction Mechanisms | Best Researcher Award

Prof. Dr. Wei Zhang | Central South University | China

Dr. Wei Zhang, born on December 29, 1977, is a leading expert in clinical pharmacology and pharmacogenomics at the Institute of Clinical Pharmacology, Central South University, China. With over two decades of dedication to personalized medicine and drug-gene interaction research, Dr. Zhang has advanced the fields of pharmacokinetics, pharmacodynamics, and gut microbiome-pharmacology interactions. His global experience includes a research stint at the University of Maryland, USA. As a professor, scientific secretary, and associate dean, he contributes significantly to clinical research, translational pharmacogenomics, and academic leadership. Dr. Zhang has led multiple national research grants and published in top-tier journals like The Lancet, Nature Communications, and Signal Transduction and Targeted Therapy. His research bridges clinical pharmacology and precision medicine, with a particular focus on diabetes, cancer immunotherapy, and microbiome-drug interactions.

Publication profile:

Scopus

✅ Strengths for the Award:

  1. Outstanding Research Leadership
    Dr. Wei Zhang has served as a principal investigator for over 7 nationally funded projects, including China’s prestigious 863 Program and multiple NSFC grants. These projects span pharmacogenomics, clinical pharmacology, and personalized medicine, highlighting his leadership in cutting-edge translational research.

  2. Pioneering Work in Pharmacogenomics & Microbiome
    He has contributed significantly to the drug-gene-microbiota interaction field, especially in type 2 diabetes, cancer immunotherapy, and nephrotoxicity. His discoveries on SLCO1B1, TRIB3, OATP1B1, and CYP2A6 variations have direct implications for individualized therapy.

  3. Global Research Recognition
    His work is published in high-impact journals such as The Lancet, Nature Communications, Signal Transduction and Targeted Therapy, and Advanced Science. These publications attest to both quality and international relevance.

  4. Interdisciplinary Innovation
    Dr. Zhang bridges clinical pharmacology, bioinformatics, and microbial science, addressing unmet needs in precision medicine. His focus on gut microbiota’s role in drug efficacy and toxicity represents a visionary, interdisciplinary approach.

  5. Academic Mentorship & Leadership
    He has held senior academic roles (Professor, Associate Dean, Scientific Secretary), contributing to the development of academic programs and mentoring the next generation of clinical pharmacologists.

  6. Award-Winning Profile
    With over 9 prestigious national awards, including the New Century Talent Award, Henry Fok Young Teacher Award, and honors from the Chinese Ministry of Education, his contributions are officially recognized at the national level.

⚠️ Areas for Improvement:

  1. International Collaboration Expansion
    While Dr. Zhang has completed a visiting scholar stint in the U.S., expanding ongoing multi-national clinical collaborations (e.g., with EU or U.S. precision medicine centers) would further globalize his impact.

  2. Public Communication & Outreach
    His work is academically impactful but could benefit from greater visibility in public health or policymaking arenas, translating research findings into clinical guidelines or patient-accessible formats.

  3. Patents & Industry Translation
    While his academic output is prolific, increased technology transfer—e.g., pharmacogenetic diagnostics or drug screening tools—would further boost his profile as a translational scientist.

🎓 Education:

Dr. Wei Zhang obtained his entire academic education from Central South University in Changsha, Hunan, China. He earned his Ph.D. in Pharmacology (2003–2006) under the mentorship of Professor Hong-Hao Zhou, a member of the China Engineering Academy. His doctoral work centered on clinical pharmacology, with strong emphasis on drug assays and clinical trials. Prior to this, he received his M.A. in Pharmacology (2001–2003), focusing on pharmacogenomics and drug metabolism, gaining hands-on expertise in pyrosequencing and human DNA analysis. Dr. Zhang began his academic journey with a B.A. in Clinical Medicine (1996–2001) from XiangYa Medical School, where he built a solid foundation in pharmacology, physiology, and clinical medicine. This comprehensive academic trajectory laid the groundwork for his research in personalized therapy, pharmacogenetics, and pharmacokinetics, making him a key contributor in China’s pharmacological landscape.

🧪 Experience:

Dr. Wei Zhang currently serves as Professor at the Department of Clinical Pharmacology, Central South University, since 2013. Since 2009, he has also held the post of Associate Dean at the Institute of Clinical Pharmacology. Previously, he was an Associate Professor (2008–2013), Head of the Genetic Testing Laboratory (2007–2013), and Lecturer (2006–2008). He also contributes administratively as the Scientific Secretary of the National Key Discipline of Pharmacology since 2005. Dr. Zhang gained international experience as a Visiting Scholar at the University of Maryland, USA (2012–2013), further broadening his research expertise. Throughout his career, he has played a pivotal role in pharmacogenomic translation, clinical trials, and precision medicine development, mentoring students and managing large research teams. His leadership and administrative skills have contributed to elevating China’s presence in global pharmacology research.

🏅 Awards and Honors:

Dr. Wei Zhang’s distinguished career has been recognized with numerous prestigious awards. As a student, he received the “Class I Scholarship” and “Outstanding Postgraduate Student” awards in 2004 and 2005, followed by the “Excellent Report Award” from the Chinese Pharmacological Society in 2005. In 2006, he was named an Outstanding Graduate by Central South University. His research excellence earned him the “New Century Excellent Talents” award from the Chinese Ministry of Education in 2010 and the Science and Technology Prize of the Chinese Society of Pharmacy. He received international recognition in 2012 with a foreign fund from the China Scholarship Council. He was also honored as an “Outstanding Young Talent” by the Organization Department of China in 2013, and in 2014 received the esteemed “Henry Fok Young Teacher Award.” These accolades underscore his influential contributions to pharmacogenomics and clinical research in China.

🔬 Research Focus:

Dr. Wei Zhang’s research is centered around clinical pharmacology, pharmacogenomics, and drug-microbiome interactions, with a mission to enable personalized medicine. His work investigates the genetic and microbial determinants of drug efficacy, toxicity, and metabolism, especially in type 2 diabetes, cancer immunotherapy, and nephrotoxic drugs like cisplatin. He has led major national projects funded by the National Natural Science Foundation of China and the 863 Program, exploring the pharmacogenomic landscape and the gut microbiota’s impact on drug response. Dr. Zhang’s translational focus bridges laboratory findings to clinical application, utilizing genomic tools and bioinformatics to optimize therapy. His innovative research has unveiled how bacterial metabolites and transporters influence drug absorption and immune modulation, contributing significantly to the understanding of precision pharmacology. Through interdisciplinary collaborations, his work pushes boundaries in oncology, endocrinology, and microbiome science.

📚 Publications Top Notes:

  1. 🧬 SLCO1B1 variants and enalapril-induced coughThe Lancet (2015)

  2. 💉 TRIB3 Gln84Arg and vascular complications in T2DMLancet Diabetes & Endocrinology (2016)

  3. 🧠 Pharmacogenomics of hERG potassium channelsTrends in Molecular Medicine (2013)

  4. 🌱 Eubacterium rectale enhances anti-PD1 immunotherapyResearch (2023)

  5. 💊 Bacteroides ovatus and metformin-induced B12 deficiencyNPJ Biofilms Microbiomes (2023)

  6. 🧨 Cancer nanobombs enhancing PD-L1 expressionAdvanced Science (2024)

  7. 🌿 Regulatory effects of herbal compounds on gut bacteriaPharmacological Research (2023)

  8. 🔄 Drug–microbiota interactions in precision medicineSignal Transduction and Targeted Therapy (2023)

  9. 🧫 Microbiota variation and ICI responseNature Communications (2023)

  10. 🔬 Peptides from Sutterella potentiate PD-1 blockadeGut (2024)

🧾 Conclusion:

Recommendation: Highly Suitable for Best Researcher Award

Dr. Wei Zhang exemplifies the ideal candidate for the Best Researcher Award. His robust scientific portfolio, pioneering work in pharmacogenomics and drug–microbiota interaction, along with his leadership in both academia and national projects, demonstrate excellence, innovation, and long-term impact. While further expansion into international policy or industry translation could enhance his reach, his current achievements already position him at the forefront of clinical pharmacology and personalized medicine in China and globally.

Zhijie Chang | Extracellular Vesicles | Cell Communication Award

Prof. Zhijie Chang | Extracellular Vesicles | Cell Communication Award

Prof. Zhijie Chang, Tsinghua University, China

Professor Zhijie Chang is a distinguished molecular biologist and tenured professor at the School of Medicine and School of Life Sciences, Tsinghua University, Beijing. His research spans cancer signaling pathways, extracellular vesicle-mediated communication, and stem cell therapy, especially in lung diseases and tumor biology. A seasoned scholar, Dr. Chang earned his Ph.D. in Animal Genetics and Breeding before undertaking postdoctoral training at the University of Alabama at Birmingham. He is currently a respected editor of FEBS Letters and a leader in molecular oncology in China. His recent works highlight the role of CREPT, Smad signaling, and macrophage modulation in cancer and fibrosis. Through decades of academic and translational research, he has significantly advanced our understanding of cell communication in disease contexts. With an extensive publication record in top journals, Dr. Chang remains a leading figure in Asia’s biomedical research landscape.

Publication Profile: 

Scopus

✅ Strengths for the Award:

  1. Pioneering Contributions in Cell Communication
    Prof. Chang’s research on CREPT, Smad proteins, NF-κB/Nrf2, and BMP signaling has directly advanced the understanding of how intracellular and intercellular communication impacts disease progression, especially in cancer and pulmonary disorders.

  2. High-Impact Publications
    He has numerous peer-reviewed articles in prestigious journals such as Nature Communications, Molecular Cancer, Signal Transduction and Targeted Therapy, and Journal of Biological Chemistry, many of which explore molecular and cellular communication in cancer and tissue repair.

  3. Translational Focus
    His integration of mesenchymal stem cell therapy, extracellular vesicles, and gene therapy reflects a strong translational approach, applying basic science to therapeutic innovations—a critical criterion for this award.

  4. Scientific Leadership and Mentorship
    As a tenured professor at Tsinghua University and editor at FEBS Letters, Prof. Chang is a leader in biomedical research and scientific dissemination, actively contributing to academic growth and mentorship.

⚠️ Areas for Improvement:

  1. More Global Recognition
    While well-known in Chinese biomedical circles and respected internationally through publications, increased involvement in global consortia or leadership in international collaborations would further solidify his global scientific footprint.

  2. Public/Community Science Engagement
    Enhancing visibility through public lectures, science communication platforms, or policy advisory roles could broaden the societal impact of his work.

  3. Data-Sharing and Open Science Practices
    Encouraging or highlighting open-access datasets, repositories, or reproducible workflows would align with best practices in modern cell communication research.

🎓 Education:

Professor Zhijie Chang began his academic journey at Northwestern Agricultural University in Yangling, China, where he earned his B.Sc. (1978–1982) in Animal Science. He then continued at the same institution to obtain a combined M.Sc. and Ph.D. in Animal Genetics and Breeding from 1982 to 1989. His graduate research laid the foundation for his future in molecular biology, signaling studies, and genetics. Seeking international exposure and advanced training, he undertook postdoctoral research from March 1997 to October 1998 at the University of Alabama at Birmingham, USA, in the Department of Pathology. There, he specialized in the BMP signaling pathway, gaining expertise in molecular signaling processes critical to cell communication. This blend of domestic and international education has equipped Dr. Chang with both the technical rigor and global perspective needed to pioneer breakthroughs in biomedical science.

💼 Professional Experience:

Professor Zhijie Chang has held a full professorship at Tsinghua University’s School of Medicine since June 2005, where he investigates cancer-related signaling mechanisms. Before this, he completed postdoctoral research at the University of Alabama at Birmingham, focusing on BMP signaling, which strengthened his understanding of developmental and pathological cell signaling. Over the years, he has built a highly productive research lab, contributed extensively to translational medicine, and trained numerous doctoral and postdoctoral researchers. As an editor of FEBS Letters, he also contributes to scientific publishing and peer-review processes. His roles across academia, research, and editorial boards mark him as a multifaceted scientist whose work bridges laboratory insights and therapeutic applications. His collaborative style and consistent research funding reflect his leadership and innovation in molecular oncology and regenerative medicine.

🏅 Awards and Honors:

Professor Zhijie Chang has been recognized multiple times by the Chinese Cell Biology Society for his high-impact publications. In 2003, he received the First Merit Paper Award for his groundbreaking research on hSef-mediated MAPK signaling inhibition in J. Biol. Chem. In 2005, he earned the Third Merit Paper Award for his study on CHIP-mediated degradation of Smad proteins, published in Mol. Cell. Biol.. These awards underscore his early and sustained contributions to deciphering molecular signaling pathways involved in cell communication, differentiation, and oncogenesis. His recent recognitions include publications in top-tier journals like Nature Communications, Molecular Cancer, and Signal Transduction and Targeted Therapy, indicating the continued relevance and innovation of his work. His role as an editor for FEBS Letters further highlights his stature in the field and dedication to advancing cell biology research at national and international levels.

🔬 Research Focus:

Dr. Zhijie Chang’s research primarily investigates cellular communication in cancer and inflammatory diseases, with a focus on CREPT, Smad proteins, and extracellular vesicles. His work dissects how tumor-derived signals modulate the tumor microenvironment, metastasis, and immune cell behavior. He has made critical discoveries regarding the role of CREPT in chromatin looping and transcriptional regulation, especially in triple-negative breast cancer. In pulmonary fibrosis models, he has shown how umbilical cord-derived mesenchymal stem cells (MSCs) modulate macrophage activity via secreted vesicles. Another major area is his exploration of Smurf1, PDK1–Akt, and JAK/STAT3 signaling axes, targeting them for therapeutic intervention in various cancers. His translational approach integrates gene therapy, stem cell-based treatments, and protein signaling studies, bridging basic and clinical sciences. Through collaborative and interdisciplinary methods, Dr. Chang contributes valuable insights into how cells communicate and respond in disease settings.

📚 Publication Top Notes:

  1. 📘 CREPT is required for the metastasis of triple-negative breast cancer through a co-operational-chromatin loop-based gene regulation

  2. 🧪 Clinical investigation on nebulized human umbilical cord MSC-derived extracellular vesicles for pulmonary fibrosis treatment

  3. 🧬 Gene Therapy with Enterovirus 3C Protease: A Promising Strategy for Various Solid Tumors

  4. 🌬 Umbilical cord-derived mesenchymal stem cells preferentially modulate macrophages to alleviate pulmonary fibrosis

  5. CREPT upregulates the antioxidant genes via activation of NF-κB/Nrf2 in acute liver injury

  6. 🔁 An oncoprotein CREPT functions as a co-factor in MYC-driven transformation and tumor growth

  7. 🎯 Targeting Smurf1 to block PDK1–Akt signaling in KRAS-mutated colorectal cancer

  8. 📤 Microenvironment-induced CREPT expression by cancer-derived small extracellular vesicles primes field cancerization

  9. 🔋 Oxidative phosphorylation safeguards pluripotency via UDP-N-acetylglucosamine

  10. 🍄 Lachnochromonin, a fungal metabolite from Lachnum virgineum, inhibits cell growth and promotes apoptosis in tumor cells through JAK/STAT3 signaling

🧾 Conclusion:

Professor Zhijie Chang exhibits a robust and well-established career built on investigating mechanisms of cell signaling, tumor microenvironment dynamics, and intercellular communication. His scientific rigor, translational impact, and leadership in the field of cell communication make him an outstanding candidate for the Research for Cell Communication Award. Addressing some broader outreach and open science practices could further elevate his profile, but his contributions to foundational and applied research in this domain are already exemplary.

Dalia Saleh | Cancer Cell Biology | Innovative Research Award

Prof . Dalia Saleh | Cancer Cell Biology | Innovative Research Award

Prof . Dalia Saleh | National Research Centre | Egypt

Dr. Dalia Osama Abd El Fattah Saleh is a distinguished pharmacologist with over two decades of experience in experimental pharmacology and drug development. She holds a Ph.D. in Pharmacology from Cairo University and currently serves as a Professor at the National Research Centre in Cairo, Egypt. Dr. Saleh has contributed to numerous high-impact scientific journals and has led pioneering work in the areas of metabolic disorders, drug safety, and vascular pharmacology. Her multidisciplinary collaborations and continuous professional development from institutions like King’s College London demonstrate her dedication to excellence in research and education. She is also recognized for her commitment to academic instruction and quality assurance, having served as a Quality Assurance Director. Her work bridges scientific discovery and real-world therapeutic applications, making her a strong candidate for innovation-focused research awards.

publication profile:

scopus

Strengths for the Award:

  1. Robust Academic Background:
    Dr. Saleh holds a Ph.D. in Pharmacology from Cairo University and has a long-standing academic and research career in pharmacology and drug development. Her doctoral and master’s theses reflect a strong foundation in vascular pharmacology, metabolic disorders, and endocrine influence—fields of enduring relevance.

  2. Consistent Research Productivity:
    Her recent publication record (2022–2024) is prolific and impactful, with studies published in high-visibility journals such as Scientific Reports, Biochemistry and Cell Biology, Naunyn-Schmiedeberg’s Archives of Pharmacology, and Environmental Science and Pollution Research. Her work covers cutting-edge pharmacological topics, including:

    • AMPK/mTOR signaling pathways,

    • Neuroprotection and anti-inflammatory mechanisms,

    • Herbal and synthetic compounds in disease modulation,

    • Hepatic encephalopathy, diabetic nephropathy, and cystitis models.

  3. Interdisciplinary and Translational Approach:
    Dr. Saleh bridges basic pharmacological research with clinical relevance. Her investigations into molecular pathways (e.g., NF-κB, PI3K/Akt, SIRT-1) are grounded in disease models, thus demonstrating translational potential. Her inclusion of both natural and synthetic agents further adds diversity and innovation to her research.

  4. Capacity Building and International Exposure:
    She has participated in Continuing Professional Development modules at King’s College London, emphasizing drug safety, statistics, and ethics—key areas in modern drug development. This international engagement underscores her commitment to staying updated and aligned with global standards.

  5. Institutional Contribution and Leadership:
    As a Professor and former Quality Assurance Director at the National Research Centre (NRC), she has contributed to institutional excellence, including achieving ISO 9001/2008 certification. These roles reflect her leadership, organizational, and strategic planning skills.

Areas for Improvement:

  1. Principal Investigator Leadership:
    While her name appears consistently in multi-author studies, further highlighting her role as the principal investigator (PI) or corresponding author could strengthen her case for innovation leadership.

  2. Patents or Product Development:
    There is no mention of patents or direct product development based on her findings. Translating research into tangible therapeutics or clinical trials would significantly elevate her eligibility for innovation-specific awards.

  3. Global Collaborations and Grants:
    Although she has participated in international seminars, active global collaborations or leading major international grants/projects would further establish her as a global innovator.

  4. Public/Industry Impact:
    While the academic impact is strong, showcasing industry partnerships or policy-level influence (e.g., contributions to clinical guidelines or regulatory science) would align more directly with innovation awards that emphasize practical application.

🎓 Education Summary :

Dr. Dalia Saleh completed her higher education at Cairo University’s Faculty of Pharmacy, where she earned her Master of Science in Pharmacology in 2009 and Doctor of Philosophy in Pharmacology in 2012. Her M.Sc. thesis focused on the vascular and biochemical effects of rosiglitazone in diabetic rats, reflecting early interests in metabolic pharmacology. Her Ph.D. expanded on this foundation by exploring estrogen’s potential role in managing vascular changes related to insulin resistance. Both theses demonstrated robust experimental designs and contributed new insights into the interplay between hormonal and metabolic pathways in disease models. Dr. Saleh has since built on this academic background with advanced training in clinical drug development, safety, and biostatistics at King’s College London in 2023, indicating a continued commitment to integrating modern pharmaceutical science and translational research into her academic portfolio. This rich educational foundation underpins her success as a researcher and educator.

🔬 Research Focus :

Dr. Saleh’s research focuses on experimental pharmacology, with a special interest in metabolic diseases, drug-induced toxicities, inflammation, and vascular pharmacology. Her studies frequently involve animal models to investigate the mechanisms of drug action and to evaluate the protective or therapeutic roles of natural products and synthetic compounds. A recurring theme in her work is exploring the modulation of signaling pathways like AMPK, NF-κB, PI3K/mTOR, and Nrf2 in the context of oxidative stress, inflammation, and cellular apoptosis. She has also studied the role of hormonal influences in disease models, such as estrogen’s effect on insulin resistance. Her research employs modern analytical techniques and integrates molecular biology with pharmacodynamics to derive mechanistic insights. This strong focus on mechanistic pharmacology enhances her work’s relevance in drug development, particularly for conditions such as diabetic complications, hepatic encephalopathy, nephropathy, and chemotherapy-induced toxicities.

📚 Publications Top Note:

  1. 🧪 Eugenol alleviates acrylamide-induced testicular toxicity via AMPK/pAKT/mTOR modulationScientific Reports, 2024

  2. 🧠 Trimetazidine prevents cisplatin neuropathy through AMPK, Nrf2, and NF-κB pathwaysBiochemistry and Cell Biology, 2023

  3. 🔬 Novel chromone-thiazolopyrimidines as TNF-α, IL-6, and PGE2 inhibitorsPolycyclic Aromatic Compounds, 2023

  4. 🚽 Chrysin protects against cyclophosphamide-induced hemorrhagic cystitis via anti-inflammatory signalingChemico-Biological Interactions, 2023

  5. 🧃 Linagliptin & L-arginine synergy in gastric hyperacidity via EP4 receptor upregulationNaunyn-Schmiedeberg’s Archives of Pharmacology, 2023

  6. 🧠 L-arginine reduces thioacetamide-induced hepatic encephalopathy via NF-κB downregulationEnvironmental Science and Pollution Research, 2023

  7. 🌿 Calotropis procera seed oil shows anti-inflammatory and antiparasitic activityArabian Journal of Chemistry, 2022

  8. 🛡️ Olmesartan mitigates diabetic nephropathy via AGE/PKC and TLR4/SIRT-1 pathwaysEuropean Journal of Pharmacology, 2022

  9. 🍃 Plumbago species show anti-fibrotic effects in liver fibrosis rat modelsScientific Reports, 2022

  10. 🫀 Omega-3 combats doxorubicin-induced liver toxicity via Nrf2/PI3K/Akt signalingPending Publication

Conclusion:

Dr. Dalia O. Saleh presents a strong candidacy for the Research for Innovative Research Award, particularly due to her sustained publication record, mechanistic depth in pharmacology, and commitment to professional development and institutional excellence. Her work spans innovative mechanistic explorations and novel therapeutic evaluations, showing real promise in addressing current pharmacological challenges.

Balbino Alarcón | Cancer Cell Biology | Best Researcher Award

Prof. Dr. Balbino Alarcón | Cancer Cell Biology | Best Researcher Award

Prof. Dr. Balbino Alarcón , Consejo Superior de Investigaciones Científicas , Spain

Balbino Alarcón is a leading Spanish immunologist renowned for his contributions to T cell biology and immune signaling. Currently serving as Profesor de Investigación at the Consejo Superior de Investigaciones Científicas (CSIC), he has been affiliated with the Centro de Biología Molecular Severo Ochoa since 2002. His research has played a pivotal role in uncovering mechanisms of T cell receptor (TCR) signaling and immune system regulation. Dr. Alarcón holds a PhD in Biology from the Universidad Autónoma de Madrid, where he began shaping his scientific journey in the early 1980s. Over the decades, he has authored numerous impactful publications, many in top-tier journals, and holds several patents licensed to biotech companies. His work bridges fundamental immunology with translational applications in autoimmunity and cancer. With a keen focus on molecular signaling, his research continues to influence both basic science and therapeutic innovation in immunology.

Publication Profile:

Google Scholar

✅ Strengths for the Award:

  1. Outstanding Research Contributions:
    Dr. Alarcón has made seminal contributions to immunology, especially in T cell receptor (TCR) signaling, immune synapse formation, and immune cell communication. His work has appeared in top-tier journals like Cell, Immunity, Nature Communications, and Journal of Experimental Medicine.

  2. Impactful Publications & Citations:
    His research includes several highly cited papers (e.g., >500 citations), underlining the influence of his work on the broader scientific community.

  3. Translational Achievements:
    He holds multiple patents on immunomodulatory molecules (e.g., AX-024), which were licensed to biotech company Artax Biopharma, bridging basic science and clinical application.

  4. SARS-CoV-2 Research Leadership:
    He actively contributed to COVID-19 immunity research, developing flow cytometry-based antibody detection techniques and tracking longitudinal immune responses to infection and vaccination.

  5. Longevity and Commitment:
    Over 40 years of consistent research activity, with continuous affiliation to one of Spain’s most prestigious scientific institutions, CSIC.

  6. International Collaboration:
    He co-authored papers with leaders in immunology, showing global recognition and collaboration.

🛠️ Areas for Improvement:

  • Public Engagement & Visibility:
    Despite scientific acclaim, more visibility in public science communication, conference keynote roles, or leadership in global immunology consortia would further support his candidacy.

  • Mentorship Highlighting:
    While his academic stature suggests mentorship, documentation or awards for training young scientists could enhance his profile for broader awards recognizing holistic impact.

  • Innovation Metrics:
    Increased emphasis on clinical translation or successful product development from his patents could strengthen claims to innovation-driven recognitions.

🎓 Education:

Dr. Balbino Alarcón completed his undergraduate degree (Licenciado en Biología) in 1982 and his PhD in Biology with a specialization in Biochemistry in 1985, both from the Universidad Autónoma de Madrid, Spain. During his academic formation, he developed a deep interest in immunological signaling, particularly in how T cells communicate with their environment. His early education laid the foundation for a distinguished research career that has spanned more than three decades. His doctoral studies were focused on cellular and molecular immunology, equipping him with the tools to explore intricate signaling pathways. This robust educational background positioned him for leadership roles in immunological research, both nationally and internationally. Through rigorous academic training and continuous research contributions, Dr. Alarcón has become a key figure in advancing our understanding of T cell function and immune regulation.

👨‍🔬 Experience:

Dr. Balbino Alarcón has over 40 years of experience in immunological research, with a primary focus on T cell receptor (TCR) signaling and lymphocyte activation. Since July 27, 2002, he has held the position of Profesor de Investigación at the Consejo Superior de Investigaciones Científicas (CSIC), working at the Centro de Biología Molecular Severo Ochoa in Madrid, Spain. His academic and research career began with groundbreaking studies in T cell immunobiology, leading to discoveries such as the role of conformational changes in TCR activation. Dr. Alarcón has also been deeply involved in translational research, co-developing immunomodulatory drugs and securing patents that were licensed to Artax Biopharma. He regularly collaborates with leading immunologists and institutions worldwide, contributing to high-impact publications and international scientific reviews. His expertise and sustained contributions have made him a mentor and authority in molecular immunology and T cell biology.

🏅 Awards and Honors:

Dr. Balbino Alarcón’s distinguished career is highlighted by several prestigious awards and intellectual property recognitions. He co-developed two patented immunosuppressive strategies based on TCR signaling inhibition: one disrupting the TCR-Nck interaction and another involving chromene derivatives. Both patents were licensed to Artax Biopharma, showcasing the real-world therapeutic relevance of his research. He has authored highly cited publications, including foundational work published in Cell, Immunity, and Annual Review of Immunology, with citations in the hundreds. These contributions have not only advanced the field of immunology but also positioned Dr. Alarcón as a thought leader in immune signal transduction. He has been recognized nationally and internationally for his scientific achievements, serving as an editorial contributor and co-author of influential immunological reviews. His work continues to shape both academic and pharmaceutical research, making him a strong candidate for Best Researcher Awards.

🔬 Research Focus:

Dr. Alarcón’s research centers on the molecular mechanisms governing T cell receptor (TCR) activation and signal transduction. His work dissects how T cells recognize antigens and how intracellular signaling cascades translate these interactions into immune responses. A significant aspect of his research has involved understanding the conformational dynamics of the TCR/CD3 complex and how this affects T cell sensitivity and activation thresholds. He also explores the role of RRas2 in T and B cell function, including its relevance in lymphomagenesis and autoimmunity. Recently, he has contributed to understanding immune responses to SARS-CoV-2 and methods to detect neutralizing antibodies. His interdisciplinary approach integrates cell biology, molecular immunology, and translational research, linking fundamental science to clinical applications such as vaccine development and immunotherapy. By targeting TCR-associated pathways, Dr. Alarcón’s research opens new avenues in the treatment of immune-related diseases and cancer.

📚 Publications Top Notes:

  1. 🧫 RRas2 is required for germinal center formation to aid B cells during energetically demanding processes (Sci Signal, 2018)

  2. 🧪 A window of opportunity for cooperativity in the T Cell Receptor (Nat Commun, 2018)

  3. 🧬 Antigen phagocytosis by B cells is required for a potent humoral response (EMBO Rep, 2018)

  4. ⚙️ RRAS2 shapes the TCR repertoire by setting the threshold for negative selection (J Exp Med, 2019)

  5. 💊 Small molecule AX-024 targets T cell receptor signaling by disrupting CD3ε-Nck interaction (J Biol Chem, 2020)

  6. 🧪 Flow cytometry multiplexed method for the detection of Neutralizing human antibodies to SARS-CoV-2 (EMBO Mol Med, 2021)

  7. 🧬 Antigen presentation between T-cells drives Th17 polarization under limiting antigen (Cell Rep, 2021)

  8. 🧫 Detection of sustained humoral immune response (IgG + IgA) in SARS-CoV-2 infection (Sci Rep, 2021)

  9. 🧠 SFRP1 modulates astrocyte-to-microglia crosstalk in neuroinflammation (EMBO Rep, 2021)

  10. 💉 Longitudinal dynamics of SARS-CoV-2-specific immunity after infection or vaccination (PLoS Pathog, 2021)

🧾 Conclusion:

Dr. Balbino Alarcón is a highly deserving candidate for the Best Researcher Award. His pioneering studies in T cell signaling, impactful biomedical patents, and active role in immune response to infectious diseases demonstrate excellence in both basic and translational immunology. With decades of productive research, interdisciplinary collaboration, and consistent scientific leadership, he embodies the qualities celebrated by such an award.

Allegra Wundersitz | Signal Transduction Mechanisms | Young Scientist Award

Mrs. Allegra Wundersitz | Signal Transduction Mechanisms | Young Scientist Award

Mrs. Allegra Wundersitz , RWTH Aachen University, Molekulare Ökologie der Rhizosphäre , Germany

Allegra Wundersitz is a passionate molecular biologist currently pursuing her PhD at RWTH Aachen University, Germany, in the group of Molecular Ecology of the Rhizosphere. Her research delves into the molecular mechanisms of plant oxygen sensing and the regulatory role of acyl-CoA-binding proteins (ACBPs) in stress signaling. Allegra has been recognized for her academic excellence, receiving the ISPA Poster Award and the Best Botanic Master’s Thesis Award from the German Society for Plant Sciences (DBG). With expertise in cloning, yeast-two-hybrid, luciferase complementation, and computational modeling, she seamlessly integrates biochemical and molecular approaches. Allegra actively collaborates with interdisciplinary teams, bridging plant physiology, structural biology, and molecular dynamics. Her commitment to research and mentoring makes her a promising young scientist aiming to contribute not only to fundamental plant science but also to translational applications in health and agriculture.

Publication Profile:

Orcid

✅ Strengths for the Award:

  • Innovative Research Focus: Allegra’s work on acyl-CoA-binding proteins (ACBPs) in plant oxygen sensing and stress signaling demonstrates high originality. Her approach of integrating protein biochemistry, gene regulation, and computational modeling is both novel and impactful.

  • Early Recognition: Despite being in the early stages of her career, she has received notable honors, including the ISPA Poster Award and the Best Master’s Thesis Award (DBG)—highlighting the quality and relevance of her work.

  • Interdisciplinary Collaboration: She engages with experts in molecular dynamics and structural biology, enriching her research with advanced modeling of protein mutations—showing strong collaborative and technical competencies.

  • Mentorship & Leadership: Supervising undergraduate students showcases her commitment to academic development and science communication.

  • Publication Record: Her first peer-reviewed article in New Phytologist indicates strong potential for growing her scientific influence.

🧩 Areas for Improvement:

  • Professional Engagement: Joining relevant scientific societies or organizations could enhance her visibility, offer networking opportunities, and provide access to grants or awards.

  • Industry Exposure: While her current focus is on basic science, even limited engagement with applied research or biotechnology partnerships could broaden the translational scope of her work.

  • Publication Volume: As her research matures, expanding her publication record beyond reviews into primary experimental studies will strengthen her academic profile.

🎓 Education:

Allegra Wundersitz holds a Master’s degree in Plant Molecular Biology, where her thesis on acyl-CoA-binding proteins (ACBPs) earned national recognition by the German Society for Plant Sciences in 2024. She is currently a PhD student at RWTH Aachen University, Germany, specializing in the molecular ecology of the rhizosphere. Her academic training spans core fields such as structural biochemistry, plant physiology, and gene regulation. Through hands-on learning and international workshops, she has developed technical proficiency in protein interaction assays, biosensor design, and in silico modeling. Her education emphasizes a multidisciplinary approach, blending experimental and computational biology. She has also supervised undergraduate research projects, further strengthening her academic leadership. Allegra’s educational journey reflects her deep curiosity for understanding molecular mechanisms in plant biology and their broader implications.

🧪 Experience:

Allegra’s experience is rooted in academic molecular biology research. During her Master’s and now as a PhD candidate, she has completed two significant research projects: developing plant-based oxygen biosensors and exploring the role of ACBPs in gene regulation. Her current PhD project investigates how ACBPs act as acyl-CoA receptors, mediating responses to oxygen and stress in plants. She employs techniques such as yeast two-hybrid assays, luciferase complementation, cloning, and molecular modeling. Allegra has also collaborated with experts in molecular dynamics, including Prof. Maria Fyta and Dr. Chandan Das, to simulate structural effects of ACBP mutations. She has presented her work at international conferences and received a prestigious poster award at ISPA. Allegra is gaining valuable teaching experience through undergraduate supervision, making her a well-rounded early-career scientist. Though she has not yet worked in industry, her work holds potential translational value in agriculture and health.

🔍 Research Focus:

Allegra’s research centers on the role of acyl-CoA-binding proteins (ACBPs) as key molecular players in plant oxygen sensing and stress signaling. She investigates how ACBPs function as acyl-CoA receptors and modulate gene expression through dynamic protein-protein interactions. Her goal is to uncover how lipid signals like acyl-CoAs are translated into physiological responses under stress conditions. Using a combination of experimental techniques—such as cloning, luciferase complementation assays, yeast-two-hybrid screens—and computational molecular dynamics, she deciphers the structural and functional aspects of ACBP interactions. Her research not only expands fundamental plant molecular biology but also contributes insights with potential applications in crop resilience, metabolic regulation, and even human health, given ACBPs’ links to cancer and metabolic disorders. Through interdisciplinary collaboration, Allegra aims to bridge structural biochemistry and plant physiology to understand how cells adapt to fluctuating oxygen and energy levels.

📚 Publications Top Notes:

  • 🧬 Acyl-CoA-binding proteins: bridging long-chain acyl-CoA metabolism to gene regulationTansley Insight, New Phytologist (April 22, 2025)

🧾 Conclusion:

Allegra Wundersitz is a highly promising young researcher who combines technical excellence, creativity, and interdisciplinary integration in her approach to plant molecular biology. Her foundational work on ACBPs not only deepens our understanding of plant stress responses but also hints at broader implications in health and metabolic research. With her trajectory and dedication, she is an ideal candidate for the Young Scientist Award, and this recognition would further support her impactful scientific journey.

ASLI CEYLAN | Molecular Mechanisms Signaling | Signal Transduction Award

Prof. Dr. ASLI CEYLAN | Molecular Mechanisms Signaling | Signal Transduction Award

Prof. Dr. ASLI CEYLAN , Ankara Yildirim Beyazit University , Turkey

Dr. Aslı F. Ceylan is an accomplished pharmacologist and academic with a strong foundation in medical pharmacology and translational research. Born in Ankara, Turkey, in 1977, she has dedicated over two decades to advancing our understanding of cellular signaling pathways in disease states. After earning her degrees from Ankara University, she completed a prestigious postdoctoral fellowship at the University of Wyoming, where she began her international research journey. Currently serving at Ankara Yıldırım Beyazıt University School of Medicine, she contributes to both research and education. Fluent in Turkish, English, and Spanish, Dr. Ceylan bridges global scientific collaborations. Her work spans oxidative stress, inflammation, and cellular mechanisms in cardiovascular, metabolic, and neurodegenerative diseases. She is a prolific author and recipient of several international fellowships and project grants. Dr. Ceylan stands out as a dedicated scientist whose work contributes meaningfully to the field of signal transduction and molecular pharmacology.

Publication profile:

Orcid

✅ Strengths for the Award:

  1. Extensive Research in Signal Transduction Pathways
    Dr. Ceylan’s body of work demonstrates a consistent and high-impact focus on key signal transduction pathways—including NLRP3 inflammasome activation, mitophagy, ferroptosis, oxidative stress, and autophagy—across cardiovascular, metabolic, and neurological disease models.

  2. International Research Recognition
    She has held prestigious fellowships from NIH, the American Heart Association, and INBRE, contributing to globally relevant research while collaborating with international teams, especially in the U.S. and Europe.

  3. Strong Translational Relevance
    Her research links molecular mechanisms to potential therapies, such as her exploration of aldose reductase inhibitors, natural antioxidants, and neuroprotective compounds (e.g., rosemary extracts), bridging the gap between basic science and clinical relevance.

  4. Consistent Publication Record
    Dr. Ceylan has co-authored over a dozen peer-reviewed publications in the past three years alone, with topics directly tied to signal transduction, and published in reputable journals (e.g., Biochimica et Biophysica Acta, JACC: Basic to Translational Science).

  5. Leadership and Mentorship
    As a Principal Investigator for NIH-funded thematic research projects and an academic at a medical university, she demonstrates strong leadership, mentoring capabilities, and a sustained contribution to the scientific community.

🛠️ Areas for Improvement:

  1. Greater Focus on Human Clinical Studies
    While her animal model work is comprehensive, integrating more human cell or clinical data would increase the translational applicability of her research.

  2. Expanded Thematic Clarity in Signal Transduction
    Some of her recent works, while impactful, focus broadly on pharmacological effects of natural compounds. More thematic emphasis on specific intracellular signaling cascades (e.g., MAPK, PI3K/Akt, or JAK/STAT) could strengthen her profile specifically for a signal transduction-focused award.

  3. Visibility in Global Scientific Forums
    Increased participation as a speaker, panelist, or chair in international conferences focused on signal transduction would enhance her global academic footprint.

📘 Education:

Dr. Aslı F. Ceylan completed her entire academic training in Pharmacology at the prestigious Ankara University Faculty of Pharmacy. She earned her Bachelor of Science (B.Sc.) in Pharmacy in 1998, followed by a Master of Science (M.Sc.) in Pharmacology in 2001. Her strong interest in cellular mechanisms and drug interactions led her to pursue a Ph.D. in Pharmacology, which she successfully completed in 2007. Her doctoral research was further enhanced by a research fellowship at the National Institutes of Health (NIH) during 2004-2005, providing her hands-on experience in internationally recognized labs. This rigorous academic journey solidified her expertise in pharmacological mechanisms and preclinical modeling. Her academic training was consistently supported by competitive scholarships from the Turkish Scientific and Research Council (TÜBİTAK). Dr. Ceylan’s academic path reflects a deep commitment to understanding complex cellular systems and contributes significantly to her current role as a leader in molecular pharmacology and signal transduction.

💼 Experience:

Dr. Aslı F. Ceylan is currently a faculty member at Ankara Yıldırım Beyazıt University School of Medicine, where she serves in the Department of Medical Pharmacology. She has extensive academic and research experience spanning over 20 years. Her postdoctoral research at the University of Wyoming School of Pharmacy (2008–2009) focused on cardiovascular research, where she worked on signal transduction pathways involved in heart failure and metabolic disease. She also held a Principal Investigator (PI) role in NIH-funded INBRE research projects in the U.S. from 2011 to 2020. Dr. Ceylan has consistently contributed to multi-disciplinary research projects and collaborative studies, mentoring young researchers and postgraduate students. She has a solid background in oxidative stress, inflammation, and cellular apoptosis. Her translational approach, blending basic science with therapeutic innovation, aligns perfectly with the goals of signal transduction research. Her international exposure and consistent academic productivity make her a valuable asset to any scientific initiative.

🏆 Awards and Honors:

Dr. Aslı F. Ceylan has earned numerous national and international fellowships and honors throughout her career. She was awarded the Postdoctoral Fellowship by the American Heart Association and the University of Wyoming in 2008, which significantly propelled her research on cardiovascular signaling. She also received a Ph.D. research fellowship from the NIH (2004–2005), supporting her studies in cell signaling and oxidative stress. Domestically, she was funded by TÜBİTAK (Turkish Scientific and Research Council) for both her master’s and Ph.D. degrees. Most notably, she served as Principal Investigator for NIH INBRE Thematic Research Projects from 2011 to 2020, underlining her leadership and innovation in biomedical research. These accolades reflect her ongoing commitment to excellence in pharmacological science and her impact on the field of signal transduction, particularly in cardiovascular and neurodegenerative diseases. Her strong track record of competitive funding and recognition underscores her eligibility for the Signal Transduction Award.

🔬 Research Focus:

Dr. Ceylan’s research is centered on signal transduction pathways involved in oxidative stress, inflammation, mitophagy, and ferroptosis. Her work delves into the molecular mechanisms underlying cardiovascular diseases, diabetic complications, neurodegenerative disorders, and cancer, with a particular focus on mitochondrial function and cellular defense systems. She employs both in vivo and in vitro models to study how specific pharmacological agents modulate pathways like NLRP3 inflammasome activation, aldose reductase inhibition, and autophagy. Additionally, her recent research explores the therapeutic potential of natural compounds such as carnosol, carnosic acid, and rosemary extract in modulating redox balance and apoptotic pathways. Her interdisciplinary approach links natural product pharmacology with molecular signaling, making her contributions relevant across multiple domains. The translational value of her research, aiming to bridge the gap between bench and bedside, aligns directly with the core objectives of signal transduction studies and reinforces her eligibility for this distinguished award.

📚 Publications Top Notes:

  1. 🧬 Cardiomyocyte-specific deletion of endothelin receptor A obliterates cardiac aging via mitophagy and ferroptosis (2024)

  2. 🧫 Tackling chronic wound healing using nanomaterials: Advancements and future perspectives (2023)

  3. 🧪 Dual-acting aldose reductase inhibitor impedes oxidative stress in diabetic rat tissues (2023)

  4. 👁️ Cemtirestat induces ocular defense against glycotoxic stress in diabetic rats (2023)

  5. 🍷 NLRP3 inhibition protects against ethanol-induced cardiotoxicity in FBXL2-dependent manner (2023)

  6. 💉 Oxytocin and enalapril reduce epidural fibrosis post-laminectomy in rats (2023)

  7. 🧠 Calcium dobesilate therapy in cerebral hypoxia/reperfusion injury in rats (2023)

  8. 🧬 Beclin1 deficiency attenuates alcohol-induced cardiac dysfunction via ferroptosis inhibition (2022)

  9. 💓 Parkin insufficiency exacerbates cardiac remodeling through mitochondrial Ca2+ overload (2022)

  10. ❤️‍🩹 Beclin 1 haplosufficiency compromises stem-cell cardioprotection post-MI (2022)

🧾 Conclusion:

Dr. Aslı F. Ceylan is a highly qualified, internationally active, and academically productive researcher whose expertise lies in elucidating molecular mechanisms of disease through signal transduction pathways. Her deep involvement in studies on oxidative stress, mitochondrial dynamics, inflammation, and natural product pharmacology positions her as a valuable contributor to the advancement of molecular medicine.

Given her research output, grant leadership, and commitment to translational science, she is highly suitable for the Signal Transduction Award. Her work not only contributes to the understanding of intracellular signaling but also bridges basic research with therapeutic potential, making her a standout candidate for this recognition.

Jin-Feng Hu | Molecular Mechanisms Signaling | Distinguished Scientist Award

Prof. Jin-Feng Hu | Molecular Mechanisms Signaling | Distinguished Scientist Award

Prof. Jin-Feng Hu , School of Pharmaceutical Sciences, Taizhou University, Zhejiang 318000, PR China ,China

Dr. Jin-Feng Hu is a globally recognized natural products chemist and currently serves as the Dean and Principal Investigator at the School of Pharmaceutical Sciences, Taizhou University, Zhejiang, China. With over three decades of academic and research experience, Dr. Hu has dedicated his career to discovering and developing bioactive natural products, particularly from rare and endangered plant species endemic to China. His contributions span innovative phytochemistry, drug discovery, and chemical biology. He has previously held prestigious academic positions at Fudan University and East China Normal University. Dr. Hu’s collaborations span continents, including Germany and the USA, contributing to an impressive international research profile. His work is widely published in high-impact journals and highly cited, underscoring the scientific relevance and translational potential of his discoveries.

Publication Profile:

Scopus

✅ Strengths for the Award:

  1. Prolific Contributions to Natural Products Chemistry
    Dr. Hu has made significant breakthroughs in phytochemical research, particularly focusing on rare and endangered Chinese plants, contributing both to drug discovery and biodiversity conservation.

  2. Global Research Experience
    His training and postdoctoral fellowships in leading institutions across China, Germany, and the USA (including the Hans-Knoell-Institute and the Scripps Research Institute) add to his international reputation and collaborative strength.

  3. Academic Leadership & Institutional Impact
    As a former department chair at Fudan University and current Dean at Taizhou University, Dr. Hu has not only led cutting-edge research but also shaped the academic direction of major pharmaceutical programs.

  4. High-Impact Publications
    Multiple first or last-author papers published in leading journals such as Phytochemistry, Organic Chemistry Frontiers, Bioorganic Chemistry, and Molecules—with a focus on pharmacologically relevant compounds.

  5. Innovative Research Themes
    Focused on drug resistance, inflammation, and metabolic diseases, using unique molecules like bis-diterpene heterodimers and sesquiterpenes, often with novel skeletons—this shows originality and translational potential.

⚙️ Areas for Improvement:

  1. Wider Public Recognition
    While he is highly respected in academic and pharmaceutical chemistry circles, broader science communication or participation in international awards/societies could boost global visibility.

  2. Commercialization & Patents
    Encouraging the translation of discoveries into patents or clinical trials would further highlight the real-world impact of his research.

  3. International Grant Funding
    Expansion into multinational funding sources (e.g., NIH, EU Horizon) would solidify global research integration and amplify the scale of his discoveries.

🎓 Education:

Dr. Hu earned his B.S., M.S., and Ph.D. degrees in Organic Chemistry from Lanzhou University (1986–1996). He pursued advanced training and postdoctoral research in Natural Products Chemistry at the Institute of Materia Medica, Chinese Academy of Medical Sciences, followed by a prestigious BMBF Fellowship at the Hans-Knoell-Institute (HKI) in Germany. Dr. Hu then continued his postdoctoral work in the United States—first at the University of Mississippi focusing on natural products chemistry and later at the Genomics Institute of the Novartis Research Foundation/The Scripps Research Institute, in the laboratory of renowned chemist Prof. Peter G. Schultz. His academic journey across leading institutions in China, Germany, and the US provided a robust foundation in interdisciplinary sciences and global perspectives in medicinal chemistry.

🧪 Experience:

Dr. Hu currently serves as Full Professor, Principal Investigator, and Dean of the School of Pharmaceutical Sciences at Taizhou University (2021–present). Before this, he was Chair of the Department of Natural Products Chemistry at Fudan University (2011–2021), and prior to that, Deputy Director of the MOE Key Laboratory of Brain Functional Genomics at East China Normal University (2006–2011). In each position, he has led cutting-edge research in natural products, coordinated multi-institutional collaborations, mentored numerous young scientists, and managed institutional development. His lab integrates phytochemistry, structural biology, and drug discovery platforms, focusing particularly on therapeutic leads for antimicrobial resistance, cancer, and metabolic diseases. With a career that reflects both academic excellence and applied innovation, Dr. Hu has significantly contributed to China’s leadership in pharmaceutical science.

🏆 Awards and Honors:

Dr. Hu has received multiple national and international honors, including fellowships, research grants, and awards recognizing his excellence in natural products chemistry. He was a BMBF Research Fellow in Germany, a Postdoctoral Fellow at the Novartis Genomics Institute and The Scripps Research Institute in the US, and has been a recipient of several Chinese National Natural Science Foundation awards. His leadership roles at prestigious institutions like Fudan University and East China Normal University reflect the esteem he holds within the academic community. Moreover, his publications are widely cited, and his research frequently garners attention for its innovation and societal relevance, especially in the context of preserving biodiversity and discovering drugs from endangered species. These achievements make him an outstanding candidate for a Distinguished Scientist Award.

🔬 Research Focus:

Dr. Hu’s research is centered on the discovery and development of novel bioactive compounds from rare and endangered plants endemic to China. His work emphasizes the interface of phytochemistry, chemical biology, and drug discovery, employing integrative analytical techniques like NMR, LC-MS, and bioassays. A major focus is the identification of natural inhibitors of key metabolic enzymes such as ATP-citrate lyase and ACC1, with applications in metabolic disorders and cancer. His studies also target drug-resistant bacterial infections, inflammation, and neurodegenerative diseases. By studying plants that are ecologically valuable yet scientifically underexplored, Dr. Hu not only contributes to new therapeutic leads but also aids in conservation biology and chemotaxonomy. His approach of combining traditional Chinese medicinal knowledge with modern molecular science marks him as a trailblazer in natural products-based drug discovery.

📚 Publication Top Notes:

  1. 🌲 Spiroamentotaxols A−D from Amentotaxus yunnanensis and their bioactivitiesOrganic Chemistry Frontiers (2025)

  2. 🍃 Fortunefuroic acids from Keteleeria fortunei via integrated dereplication approachPhytochemistry (2025)

  3. 🌿 Benzofurans from Parrotia subaequalis with antimicrobial activityPhytochemistry (2025)

  4. 🌸 Bis-iridoid glycosides and triterpenoids from Kolkwitzia amabilis targeting ACC1 and ACLMolecules (2024)

  5. 🍂 Platanosides from Platanus acerifolia against drug-resistant infectionsBioorganic Chemistry (2024)

  6. 🌼 Natural products from Heptacodium miconioides and their classification significancePhytochemistry (2024)

  7. 🌲 Tsugaforrestiacids A–O from Tsuga forrestii with ATP-citrate lyase inhibitionPhytochemistry (2024)

  8. 🌲 Terpenoids from Pseudotsuga forrestii as DRAK2 inhibitorsJournal of Molecular Structure (2024)

  9. 🍁 Anti-inflammatory flavonoids from Platanus acerifolia leavesPhytochemistry Letters (2024)

  10. 🌴 Fortunefuroic acid J from Keteleeria hainanensis with dual inhibitory effectsChemistry & Biodiversity (2024)

🔚 Conclusion:

Dr. Jin-Feng Hu is an exceptionally qualified candidate for the Distinguished Scientist Award. His trailblazing research in natural products chemistry, strategic leadership in academic institutions, and commitment to preserving biodiversity through medicinal innovation position him as a thought leader in his field. His work not only expands the scientific frontier of phytochemical drug discovery but also addresses urgent global health concerns such as antibiotic resistance and metabolic disease. Recognizing Dr. Hu with this award would honor a career devoted to science, mentorship, and societal benefit, while also empowering his continued excellence in the years to come.