Madeha Awad | Intracellular Transport Systems | Best Researcher Award

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Assoc. Prof. Dr. Madeha Awad | Intracellular Transport Systems | Best Researcher Award

Assoc. Prof. Dr. Madeha Awad, Sohag university, Egypt

Dr. Madeha Ahmed Aboelfadl Awad is an accomplished Associate Professor in the Physics Department, Faculty of Science, Sohag University, Egypt. Born on January 27, 1979, she has established herself as a leading researcher in the field of nanomaterials physics, with a focus on the synthesis and characterization of metal, metal oxide, and oxysulfide nanostructures. Fluent in Arabic, English, and French, Dr. Awad has contributed extensively to sustainable material applications, including photocatalysis, photodetectors, and smart coatings. Her passion for scientific inquiry and dedication to environmental and energy-related innovations have positioned her as a significant academic voice in Egypt and internationally. Married and residing in Sohag, she continues to inspire through both her teaching and prolific research publications, contributing to over 10 international journal articles and conference presentations. Dr. Awad’s interdisciplinary approach bridges materials science with real-world industrial and environmental applications.

Publication Profile:

Scopus

✅ Strengths for the Award:

  1. Innovative Research Focus:
    Dr. Awad has demonstrated consistent innovation in synthesizing and characterizing advanced nanostructured systems (metal oxides, oxysulfides, and thin films), with real-world applications in environmental remediation, energy conversion, and optoelectronics.

  2. Publication Record:
    She has published 10+ articles in reputable international journals such as Physica Scripta and Journal of Materials Science: Materials in Electronics. Many of these works address pressing global challenges, including pollution control, clean energy, and smart coatings.

  3. Multidisciplinary Impact:
    Her work intersects physics, materials science, and environmental engineering, creating sustainable technologies like photocatalysts, hydrogen generation systems, and photodetectors.

  4. Active Conference Participation:
    Dr. Awad has presented at national and international scientific conferences, sharing her findings on SnO₂ thin films and transparent conductors, reflecting leadership in academic dissemination.

  5. Academic Development:
    She has completed multiple training courses in competitive research, digital transformation, and teaching methodologies, ensuring continuous growth and contribution to higher education quality.

🧩 Areas for Improvement:

  1. International Collaborations:
    While Dr. Awad is actively publishing, there is potential for expanding collaborations with global research institutes and industrial sectors to enhance the scope and visibility of her work.

  2. Research Funding Diversification:
    Engaging in international grant applications or large-scale collaborative projects would further strengthen her research sustainability and resource access.

  3. Visibility in High-Impact Conferences:
    Increasing participation in high-impact global conferences or symposiums (e.g., MRS, APS) could amplify her academic footprint and foster more research exchange.

🎓 Education:

Dr. Awad earned her B.Sc. in Physics with a very good degree from Sohag University in 2003. She pursued her M.Sc. in Solid State Physics (2008), focusing on the structural, electrical, and optical properties of Sn-Sb-Se compounds. In 2015, she received her Ph.D. in Nanomaterials Physics for her pioneering work on ZnO-based nanomaterials. Her Ph.D. research emphasized growth and characterization techniques vital for optoelectronic applications. In October 2020, she became an Associate Professor, having specialized in the synthesis and analysis of nanostructured systems, including metal oxides and oxysulfides, with targeted industrial uses. Her academic path reflects a deep commitment to solid-state physics, materials engineering, and nanotechnology. She has also enhanced her academic competencies with digital transformation, student assessment, and competitive research training, aligning her education with modern interdisciplinary needs and research innovations.

🧪 Professional Experience:

Dr. Awad began her academic journey as an Assistant Lecturer in 2013 at Sohag University’s Physics Department. Following the completion of her Ph.D. in 2015, she was promoted to Lecturer, contributing to undergraduate and postgraduate instruction while intensifying her research. In 2020, she was appointed Associate Professor in Materials Science. Over the years, Dr. Awad has participated in international conferences, served as a research mentor, and collaborated with national and international scholars. Her expertise in synthesizing thin films and evaluating their optical, structural, and electrical characteristics has enabled her to lead multiple applied research projects. In addition to teaching and supervision, she has completed various training programs on student assessment, digital transformation, and competitive research funding. Her holistic academic profile blends high-impact research with educational excellence, making her a valuable contributor to Egypt’s scientific and academic landscape.

🔬 Research Focus:

Dr. Madeha Awad’s research focuses on the synthesis, characterization, and application of nanostructured materials, particularly metal and metal oxide thin films. Her work addresses real-world challenges through environmentally friendly solutions such as photocatalysis for pollutant degradation, hydrogen generation from seawater, and smart coatings for self-cleaning surfaces. She is also active in developing photodetectors for environmental sensing. Her interdisciplinary approach integrates solid-state physics, material science, and environmental engineering. Her recent projects involve advanced nanocomposites like In2O3/CuO and TiO2-based systems, with optimized optoelectronic and wettability properties for diverse industrial applications. By modifying surface and structural properties of nano-films, Dr. Awad aims to enhance energy efficiency, sustainability, and environmental remediation technologies. She is a strong advocate for applied research and often collaborates on global research initiatives that promote clean energy and green technologies. Her vision merges innovation with impact.

📚 Publications Top Notes:

  1. 🔬 Photocatalytic characteristics of indium oxide, copper oxide and indium oxide/copper oxide thin films on plastic waste substrates for organic pollutants degradation

  2. 🔍 Influence of oxygen flow rates on the optoelectronic properties SnO2 thin films

  3. 🌿 A comparison between the effect of zinc oxide and zinc oxide nanoparticles on the growth and metabolic processes of Cosmarium sp

  4. 🌞 Highly sensitive TiO2 based photodetector for environmental sensing applications

  5. 🔦 Optoelectronic characteristics of In2O3/CuO thin films for enhanced visible-light photodetector

  6. 🧼 Photocatalysis, wettability and optical properties of N-doped Cu2O/CuO thin films for smart coating applications

  7. 💧 Surface wettability and photocatalytic activities of ZrOxNy/Au/TeO2 trilayers for antifogging coatings

  8. ⚡ Some characteristics of Cu/Cu2O/CuO nanostructure heterojunctions and their applications in hydrogen generation from seawater

  9. 🌐 WNxOy prepared by oxidation of tungsten nitride as alternative photocatalyst to N-doped WO3

📝 Conclusion:

Dr. Madeha Ahmed Aboelfadl Awad exemplifies the qualities of a modern researcher who blends academic rigor with real-world impact. Her research in nanomaterials for environmental and energy applications is both timely and significant. With a strong foundation in materials science and a clear trajectory of impactful publications, she is an excellent candidate for the Best Researcher Award.

Amira Ibrahim | Cell Differentiation Processes | Innovative Research Award

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Dr. Amira Ibrahim | Cell Differentiation Processes | Innovative Research Award

Dr. Amira Ibrahim , Egyptian Atomic Energy Authority , Egypt

Dr. Amira Ibrahim Sayed is a dedicated academic and researcher, currently serving as a Lecturer at the National Center for Radiation Research and Technology, Atomic Energy Authority, Egypt. With a career grounded in oral medicine and radiology, Dr. Sayed demonstrates a multidisciplinary approach by integrating dental science with radiological and pharmaceutical research. She is known for her strong commitment to advancing healthcare through both education and scientific inquiry. Her diverse academic and professional background allows her to bridge the gap between clinical practice and biomedical research. Passionate about mentoring and teaching, she holds part-time academic roles at Misr University for Science and Technology. Dr. Sayed’s collaborative work in the synthesis of novel therapeutic agents highlights her innovative spirit and significant contributions to drug discovery, antiviral therapy, and radiation impact studies. Her impressive portfolio of peer-reviewed publications and participation in key academic courses make her a well-rounded candidate for the Research for Innovative Research Award.

Publication Profile: 

Google Scholar

✅ Strengths for the Award:

  1. Interdisciplinary Research Excellence
    Dr. Sayed merges expertise in oral medicine, radiology, and pharmaceutical chemistry—a rare and impactful blend. Her research spans both clinical and molecular levels, showing depth and versatility.

  2. Strong Publication Record
    With over 10 peer-reviewed publications in high-impact journals, her work is recognized across multiple fields including medicinal chemistry, antiviral therapy, and radiation sciences.

  3. Innovative Drug Discovery Focus
    Her work on the synthesis and molecular docking of pyrrolopyrimidine, benzimidazole, and thiouracil derivatives demonstrates cutting-edge innovation in developing novel therapeutic agents.

  4. Experience in Radiation Health Research
    Given her role at the National Center for Radiation Research & Technology, she actively contributes to important national research in radiation biology—an area of growing relevance.

  5. Academic and Educational Contributions
    As a lecturer at multiple institutions, she plays a vital role in knowledge transfer, student mentorship, and academic development.

  6. Multilingual Communication & Skills
    Her ability to communicate in Arabic, English, and basic German supports her involvement in international collaborations.

🛠 Areas for Improvement:

  1. Global Research Collaborations
    Greater participation in international collaborative projects, consortia, or funding initiatives would further elevate her impact and visibility.

  2. Patents and Practical Applications
    Filing for patents or translating her synthesized compounds into preclinical or clinical studies could reinforce the practical significance of her innovations.

  3. Increased Leadership Roles
    Engagement in leading research teams or coordinating large-scale projects could reflect greater influence within her scientific community.

🎓 Education:

Dr. Amira Ibrahim Sayed began her academic journey with a Bachelor’s degree in Dental Surgery (B.D.S) in 2005 from the Faculty of Oral and Dental Medicine, Cairo University. She further specialized in Oral Radiology, obtaining a Master of Science (M.Sc.) in 2014 from the same institution. Her academic curiosity and passion for interdisciplinary research led her to pursue a Ph.D. in Oral Medicine, Periodontology, Oral Diagnosis, and Radiology, which she completed in 2020 at Al-Azhar University. This diverse academic foundation has enabled her to explore the intersections of radiology, oral health, and medicinal chemistry. Dr. Sayed’s education reflects a strong emphasis on both clinical and scientific research skills, providing her with the expertise required to innovate in both diagnostic and therapeutic fields. Her comprehensive academic background makes her uniquely equipped to contribute to scientific research in radiation biology, oral diagnostics, and pharmaceutical innovation.

🧪 Experience:

Dr. Amira Ibrahim Sayed has amassed extensive academic and research experience, notably as a Lecturer at the National Center for Radiation Research & Technology, Atomic Energy Authority, since 2021. She started her professional journey there in 2015 as an Assistant Lecturer. Additionally, she contributes to higher education as a part-time Lecturer at Misr University for Science and Technology, where she also held an Assistant Lecturer role between 2015 and 2016. Her responsibilities include curriculum development, supervising student research, and lecturing in oral medicine and radiology. She has also actively participated in specialized training, such as the Ionizing Radiation Protection course, enhancing her qualifications in radiological safety. Her hands-on experience in both academic and applied research settings, combined with her interdisciplinary work in pharmacology and medical imaging, highlights her competence in navigating complex scientific challenges. Her professional trajectory is a testament to her adaptability, diligence, and commitment to innovation in health sciences.

🔬 Research Focus:

Dr. Amira Ibrahim Sayed’s research is centered around oral radiology, radiation protection, and the synthesis of novel pharmaceutical agents with therapeutic potential. Her interdisciplinary work bridges oral health sciences with medicinal chemistry, aiming to improve diagnostics and treatments in fields such as oncology, virology, and inflammation. She has explored the biological effects of magnetic resonance imaging and radiation on dental restorations and bone healing, highlighting her commitment to clinical relevance. Moreover, her innovative research on pyrrolopyrimidine and benzimidazole derivatives positions her at the forefront of drug discovery, particularly in antiviral, antifungal, and anti-inflammatory domains. Dr. Sayed utilizes molecular docking and simulation techniques to predict compound efficacy and mechanism of action. Her dedication to enhancing patient care through translational research, combined with a strong publication record in peer-reviewed journals, showcases her as a forward-thinking scientist making meaningful contributions to biomedical innovation.

📚 Publications Top Notes:

  1. 🧲 Effect of Magnetic Resonance Imaging on Microleakage of Amalgam Restoration

  2. 🦴 Radiographic and Histopathologic Evaluation of L-Carnitine and Vitamin E Efficacy on Irradiated Jaw Bones

  3. 🧪 Synthesis of Certain Pyrimidine Derivatives as Antimicrobial and Anti-inflammatory Agents

  4. 🧬 Design, Synthesis, and Molecular Docking of Pyrrolopyrimidine Derivatives as NS5B Polymerase Inhibitors

  5. 🦠 Novel Antiviral Compounds Against Gastroenteric Viral Infections

  6. 🧫 Synthesis of Novel Pyrroles and Fused Pyrroles as Antifungal and Antibacterial Agents

  7. 💊 Synthesis Strategies and Biological Value of Pyrrole and Pyrrolopyrimidine

  8. 🧯 Design and Evaluation of Pyrrolopyrimidine Derivatives as Antioxidant and Anti-inflammatory Agents

  9. 🦠 Evaluation of Pyrrolopyrimidine Derivatives as Antivirals Against Gastroenteric Viruses

📝 Conclusion:

Dr. Amira Ibrahim Sayed is a highly suitable candidate for the Research for Innovative Research Award. Her commitment to interdisciplinary innovation, particularly in radiation research and therapeutic compound development, aligns well with the award’s objective to honor groundbreaking scientific contributions. With a strong track record of impactful publications and academic leadership, she stands out as a researcher dedicated to improving health outcomes through science. Strengthening her global collaborations and translating research into applications will only further her potential for scientific excellence and recognition.

Zhirong Tan | Gene Regulation Epigenetics | Best Researcher Award

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Prof. Zhirong Tan | Gene Regulation Epigenetics | Best Researcher Award

Prof. Zhirong Tan  , Xiangya Hospital, Central South University , China

Professor Zhirong Tan is a leading Chinese expert in pharmacogenomics and clinical pharmacology. Currently a professor at Xiangya Hospital, Central South University, he also serves as the Director of the Pharmacogenetics and Pharmacokinetics Research Laboratory and Deputy Director of the Drug Analysis Center. He has been instrumental in over 300 clinical trials, pushing forward the frontiers of precision medicine, especially in colorectal cancer and Alzheimer’s disease. With over 20 SCI papers, multiple patents, and co-authorship of four books, he’s widely recognized for his work in pharmacokinetics and biomarker discovery. A national GCP and GMP inspector, Prof. Tan actively contributes to pharmaceutical regulation and innovation in China. His academic and industry partnerships reflect a robust foundation in translational research and real-world drug development.

Publication Profile: 

Google Scholar

✅ Strengths for the Award:

  1. Extensive Research Contributions
    Prof. Zhirong Tan has made outstanding contributions to clinical pharmacology, pharmacogenetics, and metabolomics over two decades. His research has provided critical insights into drug metabolism, biomarker discovery, and precision medicine, especially in colorectal cancer and Alzheimer’s disease.

  2. Prolific Publication Record
    With over 22 SCI-indexed publications (first or corresponding author) and 6 CSCD papers, Prof. Tan’s research has achieved over 3550 citations and an H-index of 33 on Web of Science—evidence of the high impact and recognition of his work.

  3. Strong National & Industry Collaborations
    He has participated in or led 300+ clinical trials and secured 5 “Million+” industry-funded projects, reflecting strong ties with both academia and industry. His leadership in national-level projects, such as the “Major New Drug Development” program, showcases his influence in China’s healthcare innovation.

  4. Intellectual Property and Innovation
    With 3 granted patents and 3 under review, Prof. Tan’s ability to translate research into practical applications is evident. His individualized esomeprazole dosing regimen highlights innovation at the clinical level.

  5. Regulatory & Policy Contributions
    As a national GCP/GMP inspector, he plays a pivotal role in drug trial ethics and compliance in China. He also holds leadership roles in pharmacogenomics committees, further demonstrating his commitment to public health advancement.

  6. Academic Mentorship and Editorial Work
    In addition to research, Prof. Tan contributes as a journal reviewer, co-author of four textbooks, and mentor to the next generation of scientists, reinforcing his role as a thought leader in the field.

🔍 Areas for Improvement:

  1. International Visibility
    While Prof. Tan’s national presence is remarkable, further international collaborations, invited keynotes at global conferences, or leading roles in global consortia could enhance his visibility and expand the influence of his work.

  2. Broader Publication Range
    Publishing more frequently in top-tier international journals (e.g., Nature, The Lancet, NEJM) would increase the global academic reach of his findings.

  3. Open Science & Data Sharing
    As the field moves toward transparency, incorporating open-access publications and shared data repositories could boost both reproducibility and citations.

🎓 Education:

Professor Zhirong Tan obtained his Ph.D. from Central South University, a premier Chinese institution, where he laid the groundwork for his expertise in clinical pharmacology and pharmacogenomics. He later pursued postdoctoral research at the School of Pharmacy, University of Maryland, Baltimore, one of the top pharmaceutical research institutions in the United States. This international experience enabled him to gain a global perspective in drug metabolism, biomarker identification, and translational pharmacology. His academic training focused on cutting-edge methodologies such as metabolomics, pharmacokinetics, and precision medicine. Through continuous education and research, he has built a reputation as a highly skilled pharmacologist whose work bridges basic research and clinical applications.

💼 Experience:

With a research career spanning over two decades since 1998, Professor Zhirong Tan has led and participated in numerous national-level and provincial-level projects, including China’s National Science and Technology Major Projects. He currently holds multiple leadership positions at Xiangya Hospital, Central South University. Over the years, he has completed major research grants from NSFC, the Hunan Province, and the Ministry of Science and Technology. As a GCP and GMP inspector, Prof. Tan has overseen more than 300 clinical trials, ensuring drug development meets regulatory and ethical standards. His experience also extends to industry collaboration, with successful execution of 5 “Million+” funded projects and influential roles in pharma-academic alliances. A frequent peer reviewer and contributor to international journals, his work influences both the scientific community and regulatory frameworks.

🔬 Research Focus:

Professor Tan’s primary research focus lies in clinical pharmacology, pharmacogenomics, and metabolomics, particularly for colorectal cancer and Alzheimer’s disease. His work aims to identify and validate biomarkers for disease diagnosis, drug efficacy, and toxicity prediction. A major contributor to China’s “Major New Drug Development” initiative, he has developed personalized esomeprazole dosing regimens by studying genetic polymorphisms, SNPs, and microRNA interactions. His research also explores the pathogenesis of Alzheimer’s disease using metabolomic profiling, offering insights into early detection and potential therapeutics. He applies advanced bioanalytical methods to understand inter-individual variability in drug metabolism and therapeutic response. His projects have real-world clinical implications, transforming how drugs are prescribed, regulated, and monitored. Through his pioneering work, Prof. Tan contributes significantly to the evolution of precision medicine in China.

📚 Publication Top Notes:

  1. 📊 Role of BCRP 421C>A polymorphism on rosuvastatin pharmacokinetics in healthy Chinese males

  2. ❤️ Gly389Arg polymorphism of β1‐adrenergic receptor and cardiovascular response to metoprolol

  3. 💊 CYP2C19 ultra-rapid metabolizer genotype affects voriconazole pharmacokinetics

  4. 🧬 HLA‐B35:01 allele as biomarker for Polygonum multiflorum–induced liver injury*

  5. 🌿 Repeated berberine administration inhibits cytochromes P450 in humans

  6. 💉 Effect of SLCO1B1 polymorphism on pharmacokinetics of nateglinide

  7. 🧪 Assessment of cytochrome P450 activity by five‐drug cocktail approach

  8. ☕ Plasma caffeine metabolite ratio linked to CYP1A2 polymorphisms

  9. 🔬 Inducibility of CYP1A2 by omeprazole associated with genetic polymorphism

  10. 🧫 Ile118Val polymorphism of CYP3A4 affects simvastatin lipid-lowering efficacy

📝 Conclusion:

Professor Zhirong Tan is a highly deserving candidate for the Best Researcher Award. His record of scientific excellence, clinical innovation, and regulatory leadership clearly positions him as a key contributor to modern pharmacology. His integrated approach—spanning basic science, clinical trials, and health policy—has had a measurable impact on patient care and drug development in China.

While there is room to further expand his global footprint, his accomplishments to date already demonstrate the caliber, commitment, and consistency expected of a world-class researcher.

Xingting Guo | Stem Cell Research | Best Researcher Award

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Assist. Prof. Dr. Xingting Guo | Stem Cell Research | Best Researcher Award

Assist. Prof. Dr. Xingting Guo , Peking University Third Hospital , China

Dr. Xingting Guo is a dedicated postdoctoral fellow at the National Institute of Biological Sciences (NIBS), Beijing, where she has been working since 2018. With a strong academic foundation in biochemistry and molecular biology, her research delves into stem cell biology, cellular differentiation, and tumorigenesis using Drosophila and mouse models. Her expertise lies in integrating genetics, biochemistry, single-cell sequencing, and bioinformatics to unravel mechanisms of cell fate specification and intestinal homeostasis. Dr. Guo has co-authored several high-impact publications and has presented her research at both national and international conferences. Her contributions have significantly advanced our understanding of enteroendocrine cells (EECs), tissue identity, and inter-organ communication. Passionate and detail-oriented, she is actively contributing to biomedical sciences with a vision to translate fundamental biology into therapeutic insights. Her work is paving the way for novel treatments for metabolic diseases and cancers.

Publication Profile:

Scopus

✅ Strengths for the Award:

  1. Innovative Research Focus: Dr. Guo has made pioneering contributions in stem cell biology, particularly in understanding cell fate specification, enteroendocrine diversity, and tumor suppression using Drosophila and murine models.

  2. Multidisciplinary Skillset: She integrates genetics, high-throughput sequencing, bioinformatics, organoid culture, and in vivo models, showcasing deep technical expertise.

  3. High-Impact Publications: Co-first author in multiple peer-reviewed journals, including Cell Reports, Nature Communications, and FEBS Journal.

  4. Leadership in Research: From graduate researcher to postdoctoral fellow, she has led multiple independent projects, contributing novel findings to developmental and regenerative biology.

  5. International Recognition: Regular presenter at top-tier conferences globally, including the European Drosophila Research Conference and Annual Drosophila Research Conference (USA).

  6. Research Funding: Successfully secured National Natural Science Foundation of China funding, reflecting scientific merit and recognition.

🔍 Areas for Improvement:

  1. Broader Collaboration: Expanding collaborations outside her current institute or internationally may enhance the translational reach and impact of her research.

  2. Mentorship Roles: While her research is strong, formal mentorship roles (e.g., supervising Ph.D. students) or teaching contributions could further demonstrate leadership.

  3. Clinical Translation: Though her mouse model work touches on therapeutic discovery, publishing more translational or clinical-facing studies could boost her impact in applied biomedical research.

🎓 Education:

Dr. Xingting Guo earned her Ph.D. in Biochemistry and Molecular Biology from the College of Life Sciences at Beijing Normal University (2012–2018), where she began her in-depth research on stem cell biology and tissue differentiation in Drosophila. Prior to this, she completed her Bachelor’s degree in Biological Engineering at Nanjing Agricultural University (2008–2012), where she was honored with multiple scholarships for academic excellence. Throughout her education, she developed a robust foundation in molecular biology, genetics, and developmental biology, equipping her with the skills to tackle complex biological questions. Her academic journey has been characterized by continuous academic excellence, curiosity-driven research, and a commitment to uncovering the molecular mechanisms of health and disease. Her education laid the groundwork for her successful transition to cutting-edge postdoctoral research in developmental biology and regenerative medicine.

💼 Experience:

Dr. Guo began her research career at NIBS Beijing as a graduate student in 2012, transitioning into a postdoctoral fellow in 2018 under the mentorship of Dr. Rongwen Xi. Her research primarily uses Drosophila intestinal systems and murine models to explore the regulation of cellular identity, differentiation, and plasticity. She has led multiple projects on tumor suppression, transcriptional regulation, and enteroendocrine diversity using advanced techniques like genetic manipulation, single-cell RNA sequencing, and organoid cultures. Additionally, she contributes to translational research by identifying drug targets for diabetes-related therapy by reprogramming intestinal cells into insulin-producing β-cells. Her interdisciplinary approach and long-standing expertise in stem cell biology highlight her versatility and innovation in research. Her consistent progression from graduate student to independent researcher reflects her strong scientific rigor and leadership in high-impact studies.

🏆 Awards and Honors:

Dr. Xingting Guo has been recognized for her academic excellence and scientific contributions through numerous honors. During her Ph.D., she was awarded the First Class Academic Scholarship for two consecutive years (2014–2016). As an undergraduate, she earned the prestigious Cyrus Tang Scholarship four times, along with the First Class Scholarship at Nanjing Agricultural University. In recent years, she has taken on the role of a peer reviewer for Bio-protocols, highlighting her engagement with the scientific community. Dr. Guo’s research excellence has led her to represent her work at top-tier conferences, including the Annual Drosophila Research Conference (USA) and the European Drosophila Research Conference (Switzerland). Her contributions were also supported by a grant from the National Natural Science Foundation of China (Grant No. 3210050518), demonstrating her ability to secure competitive funding. These accolades mark her as a rising star in molecular and developmental biology.

🔬 Research Focus:

Dr. Guo’s research focuses on the molecular regulation of stem cell differentiation, cellular identity maintenance, and neuroendocrine cell plasticity using Drosophila and mouse models. She investigates how transcription factors such as ttk69 influence enteroendocrine (EEC) specification, tissue homeostasis, and tumor suppression. Using cutting-edge tools like CRISPR, single-cell transcriptomics, and in vivo lineage tracing, she deciphers how intestinal stem cells differentiate into diverse terminal cell types. Her recent work explores how intestinal EECs regulate systemic physiology via neuropeptides in response to environmental cues like starvation and mating. In parallel, she studies cell-fate reprogramming in mammals to identify potential therapeutic strategies for diabetes by inducing insulin-producing cells in the gut. By bridging basic biology with translational goals, her work contributes to regenerative medicine, oncology, and metabolic disease research.

📚 Publications Top Notes:

  • 🧠 Cell-fate conversion of intestinal cells in adult Drosophila midgut by depleting a single transcription factor, Nature Communications, 2024

  • 🔍 The Specification and Function of Enteroendocrine Cells in Drosophila and Mammals: A Comparative Review, FEBS Journal, 2021

  • 🧬 A Switch in Tissue Stem Cell Identity Causes Neuroendocrine Tumors in Drosophila Gut, Cell Reports, 2020

  • 🧫 The Cellular Diversity and Transcription Factor Code of Drosophila Enteroendocrine Cells, Cell Reports, 2019

  • 🧬 Division of Labor: Roles of Groucho and CtBP in Notch-Mediated Lateral Inhibition, Stem Cell Reports, 2019

  • 📘 Signaling Pathways Regulating Stem Cells, Book Chapter, Springer, 2015

  • 🛑 Ttk69 acts as a master repressor of enteroendocrine cell specification, Development, 2015

  • 🧪 EGFR and Notch signaling regulate gastric stem cells, Cell Research, 2014

  • 🧠 Sox9 Ortholog Regulates Intestinal Homeostasis and Regeneration in Drosophila, Cell Reports, 2020

🧾 Conclusion:

Dr. Xingting Guo is a highly qualified and deserving candidate for the Best Researcher Award. Her exceptional track record in stem cell biology, cellular reprogramming, and disease modeling makes her a rising star in the life sciences. With a unique combination of technical excellence, scientific innovation, and publication strength, she has already made a significant impact on our understanding of intestinal cell biology and endocrine regulation. Addressing a few career development aspects—like expanding collaborative networks and clinical translation—will make her an even more formidable leader in the field. Given her achievements, potential, and contributions, she is strongly recommended for this prestigious honor.