Charles Wang | Epigenomics | Distinguished Scientist Award

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Prof. Charles Wang | Epigenomics | Distinguished Scientist Award

Prof. Charles Wang | Loma Linda University Center for Genomics | United States

Dr. Changhong Wang (now known as Dr. C. Wang), a U.S. citizen, is a distinguished molecular toxicologist and genomic scientist currently serving as Director and Tenured Professor at the Center for Genomics, Loma Linda University. Originally from China, Dr. Wang holds dual graduate degrees in Public Health and Toxicology from Tongji Medical University and the University of Washington, respectively. His early career laid the foundation for pivotal research into environmental toxicants and gene-environment interactions. Dr. Wang has significantly contributed to the understanding of xenobiotic metabolism, DNA methylation, and the transgenerational effects of toxins and epigenetics. His leadership in molecular genetics research is reflected in numerous peer-reviewed publications and competitive grants. A passionate educator and mentor, Dr. Wang’s work bridges foundational science and clinical application, marking him as a strong contender for the Research for Distinguished Scientist Award.

Publication Profile: 

Socpus

Education:

Dr. Wang received his Ph.D. in Toxicology from the University of Washington, Seattle. His doctoral work focused on aflatoxin metabolism and liver glutathione S-transferases in nonhuman primates, mentored by Dr. David L. Eaton. Prior to that, he earned an MPH in Environmental Epidemiology from Tongji Medical University, China, where he developed a foundation in public health and environmental sciences. His dual training in toxicology and epidemiology provided a unique cross-disciplinary approach to health sciences. This strong academic background enables Dr. Wang to address critical questions regarding how environmental exposures affect human health, especially through epigenetic and genomic pathways. His educational path reflects a continuous pursuit of scientific excellence and translational impact, positioning him to bridge molecular discoveries with public health relevance—a crucial quality for a candidate of the Distinguished Scientist Award.

Experience:

Dr. Wang currently serves as Director and Tenured Professor at the Center for Genomics, School of Medicine, Loma Linda University (LLU), where he has led translational and mechanistic genomic research. His responsibilities span academic leadership, mentorship, and collaborative research within the Division of Molecular Genetics. Prior to this, he held the role of Associate Professor-Adjunct in Microbiology & Molecular Genetics at LLU. His earlier roles include postdoctoral and research scientist positions at institutions where he investigated environmental carcinogens, drug metabolism, and gene expression. Over three decades, Dr. Wang has built a multidisciplinary portfolio in toxicology, environmental health, and genomics. He is a leading voice in DNA methylation, epigenetic inheritance, and cancer biology. His integrative research style and administrative skills have allowed him to create impactful programs that foster innovation and interdisciplinary collaboration—an essential trait for any distinguished scientist.

Awards and Honors:

Dr. Wang’s academic journey has been decorated with prestigious accolades from the outset. He received the Excellent Medical Student Award  and Distinguished Graduate Student Award from Tongji Medical University. His pioneering research at the University of Washington earned him the First-Place Graduate Award for Research Excellence from the Society of Toxicology in New Orleans. He was awarded multiple Student Travel Awards from the University of Washington’s School of Public Health. These early recognitions underscore his long-standing commitment to scientific excellence and innovation. Dr. Wang’s later career has been marked by continuous success in publication, grant acquisition, and institutional leadership. These honors reflect both peer recognition and academic merit, reinforcing his status as a credible and outstanding candidate for the Research for Distinguished Scientist Award.

Research Focus:

Dr. Wang’s research focuses on environmental toxicology, genomics, and epigenetics, particularly in the context of transgenerational health effects. He investigates how toxicants such as cadmium, aflatoxin B1, and p,p’-DDE affect gene regulation through epigenetic reprogramming. His lab has pioneered work on DNA methylation, histone modifications, and miRNA signatures in diseases like cancer, neurodevelopmental disorders, and diabetes. Recent work has addressed the effects of e-cigarette exposure on neonatal brain methylomes and the epigenetic inheritance of addiction vulnerability. Dr. Wang also explores copy number variation and drug resistance mechanisms in oncology, using cutting-edge tools like single-cell RNA sequencing and patient-derived models. His integrative, multi-omics approach allows for deep mechanistic insights and clinical translation. His ability to lead multidisciplinary teams in high-impact research areas demonstrates both visionary thinking and the technical prowess necessary for distinguished scientific leadership.

Publications Top Notes:

  1. Cadmium-induced negative calcium balance in multiparous birth women

  2. Effect of cadmium on bone calcium in nonpregnant mice: Direct evidence on bone

  3. Cadmium’s impact on bone calcium in mouse dams: Itai-Itai-like syndrome model

  4. Induction of drug-metabolizing enzymes by BHA, ethoxyquin, and oltipraz

  5. Diquat and ciprofibrate effects on hepatic enzyme expression

  6. Mu-class GSTs mediate aflatoxin B1 epoxide conjugation in Macaca liver

  7. CYP1B1 expression analyzed in human tissues via hybridization techniques

  8. Cloning and characterization of alpha-class GSTs from Macaca liver

  9. Proteomic comparison of hepatocyte preparation methods

  10.  CYP3A41B polymorphism linked to puberty onset and breast cancer risk*

Conclusion:

In conclusion, Dr. Wang’s long-standing academic excellence, innovative research in toxicogenomics, and his leadership in advancing our understanding of environmental and epigenetic factors in disease clearly distinguish him as an outstanding scientist. His achievements fulfill and surpass the expectations for the Research for Distinguished Scientist Award. His profile reflects not only a deep commitment to rigorous science but also a visionary approach to public health and molecular research. With minor expansion in global engagement and translational outreach, Dr. Wang’s impact could be even more far-reaching. He is highly recommended for this honor.

Amira Ibrahim | Cell Differentiation Processes | Innovative Research Award

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Dr. Amira Ibrahim | Cell Differentiation Processes | Innovative Research Award

Dr. Amira Ibrahim , Egyptian Atomic Energy Authority , Egypt

Dr. Amira Ibrahim Sayed is a dedicated academic and researcher, currently serving as a Lecturer at the National Center for Radiation Research and Technology, Atomic Energy Authority, Egypt. With a career grounded in oral medicine and radiology, Dr. Sayed demonstrates a multidisciplinary approach by integrating dental science with radiological and pharmaceutical research. She is known for her strong commitment to advancing healthcare through both education and scientific inquiry. Her diverse academic and professional background allows her to bridge the gap between clinical practice and biomedical research. Passionate about mentoring and teaching, she holds part-time academic roles at Misr University for Science and Technology. Dr. Sayed’s collaborative work in the synthesis of novel therapeutic agents highlights her innovative spirit and significant contributions to drug discovery, antiviral therapy, and radiation impact studies. Her impressive portfolio of peer-reviewed publications and participation in key academic courses make her a well-rounded candidate for the Research for Innovative Research Award.

Publication Profile: 

Google Scholar

✅ Strengths for the Award:

  1. Interdisciplinary Research Excellence
    Dr. Sayed merges expertise in oral medicine, radiology, and pharmaceutical chemistry—a rare and impactful blend. Her research spans both clinical and molecular levels, showing depth and versatility.

  2. Strong Publication Record
    With over 10 peer-reviewed publications in high-impact journals, her work is recognized across multiple fields including medicinal chemistry, antiviral therapy, and radiation sciences.

  3. Innovative Drug Discovery Focus
    Her work on the synthesis and molecular docking of pyrrolopyrimidine, benzimidazole, and thiouracil derivatives demonstrates cutting-edge innovation in developing novel therapeutic agents.

  4. Experience in Radiation Health Research
    Given her role at the National Center for Radiation Research & Technology, she actively contributes to important national research in radiation biology—an area of growing relevance.

  5. Academic and Educational Contributions
    As a lecturer at multiple institutions, she plays a vital role in knowledge transfer, student mentorship, and academic development.

  6. Multilingual Communication & Skills
    Her ability to communicate in Arabic, English, and basic German supports her involvement in international collaborations.

🛠 Areas for Improvement:

  1. Global Research Collaborations
    Greater participation in international collaborative projects, consortia, or funding initiatives would further elevate her impact and visibility.

  2. Patents and Practical Applications
    Filing for patents or translating her synthesized compounds into preclinical or clinical studies could reinforce the practical significance of her innovations.

  3. Increased Leadership Roles
    Engagement in leading research teams or coordinating large-scale projects could reflect greater influence within her scientific community.

🎓 Education:

Dr. Amira Ibrahim Sayed began her academic journey with a Bachelor’s degree in Dental Surgery (B.D.S) in 2005 from the Faculty of Oral and Dental Medicine, Cairo University. She further specialized in Oral Radiology, obtaining a Master of Science (M.Sc.) in 2014 from the same institution. Her academic curiosity and passion for interdisciplinary research led her to pursue a Ph.D. in Oral Medicine, Periodontology, Oral Diagnosis, and Radiology, which she completed in 2020 at Al-Azhar University. This diverse academic foundation has enabled her to explore the intersections of radiology, oral health, and medicinal chemistry. Dr. Sayed’s education reflects a strong emphasis on both clinical and scientific research skills, providing her with the expertise required to innovate in both diagnostic and therapeutic fields. Her comprehensive academic background makes her uniquely equipped to contribute to scientific research in radiation biology, oral diagnostics, and pharmaceutical innovation.

🧪 Experience:

Dr. Amira Ibrahim Sayed has amassed extensive academic and research experience, notably as a Lecturer at the National Center for Radiation Research & Technology, Atomic Energy Authority, since 2021. She started her professional journey there in 2015 as an Assistant Lecturer. Additionally, she contributes to higher education as a part-time Lecturer at Misr University for Science and Technology, where she also held an Assistant Lecturer role between 2015 and 2016. Her responsibilities include curriculum development, supervising student research, and lecturing in oral medicine and radiology. She has also actively participated in specialized training, such as the Ionizing Radiation Protection course, enhancing her qualifications in radiological safety. Her hands-on experience in both academic and applied research settings, combined with her interdisciplinary work in pharmacology and medical imaging, highlights her competence in navigating complex scientific challenges. Her professional trajectory is a testament to her adaptability, diligence, and commitment to innovation in health sciences.

🔬 Research Focus:

Dr. Amira Ibrahim Sayed’s research is centered around oral radiology, radiation protection, and the synthesis of novel pharmaceutical agents with therapeutic potential. Her interdisciplinary work bridges oral health sciences with medicinal chemistry, aiming to improve diagnostics and treatments in fields such as oncology, virology, and inflammation. She has explored the biological effects of magnetic resonance imaging and radiation on dental restorations and bone healing, highlighting her commitment to clinical relevance. Moreover, her innovative research on pyrrolopyrimidine and benzimidazole derivatives positions her at the forefront of drug discovery, particularly in antiviral, antifungal, and anti-inflammatory domains. Dr. Sayed utilizes molecular docking and simulation techniques to predict compound efficacy and mechanism of action. Her dedication to enhancing patient care through translational research, combined with a strong publication record in peer-reviewed journals, showcases her as a forward-thinking scientist making meaningful contributions to biomedical innovation.

📚 Publications Top Notes:

  1. 🧲 Effect of Magnetic Resonance Imaging on Microleakage of Amalgam Restoration

  2. 🦴 Radiographic and Histopathologic Evaluation of L-Carnitine and Vitamin E Efficacy on Irradiated Jaw Bones

  3. 🧪 Synthesis of Certain Pyrimidine Derivatives as Antimicrobial and Anti-inflammatory Agents

  4. 🧬 Design, Synthesis, and Molecular Docking of Pyrrolopyrimidine Derivatives as NS5B Polymerase Inhibitors

  5. 🦠 Novel Antiviral Compounds Against Gastroenteric Viral Infections

  6. 🧫 Synthesis of Novel Pyrroles and Fused Pyrroles as Antifungal and Antibacterial Agents

  7. 💊 Synthesis Strategies and Biological Value of Pyrrole and Pyrrolopyrimidine

  8. 🧯 Design and Evaluation of Pyrrolopyrimidine Derivatives as Antioxidant and Anti-inflammatory Agents

  9. 🦠 Evaluation of Pyrrolopyrimidine Derivatives as Antivirals Against Gastroenteric Viruses

📝 Conclusion:

Dr. Amira Ibrahim Sayed is a highly suitable candidate for the Research for Innovative Research Award. Her commitment to interdisciplinary innovation, particularly in radiation research and therapeutic compound development, aligns well with the award’s objective to honor groundbreaking scientific contributions. With a strong track record of impactful publications and academic leadership, she stands out as a researcher dedicated to improving health outcomes through science. Strengthening her global collaborations and translating research into applications will only further her potential for scientific excellence and recognition.