Mariana Grieben | Cancer Cell Biology | Best Researcher Award

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Dr. Mariana Grieben | Cancer Cell Biology | Best Researcher Award

University of Lübeck | Germany

Dr. Mariana Grieben is a biochemist and structural biologist whose research spans the molecular mechanisms of membrane proteins and virus-host interactions. She earned her Ph.D. in structural biology with a focus on ATP synthases and subsequently advanced her expertise as a postdoctoral researcher at the Structural Genomics Consortium (SGC), University of Oxford, where she investigated the structural characterization of human integral membrane proteins, including TRP channels, TMEM proteins, and SLCs, in collaboration with pharmaceutical companies to identify therapeutic small molecules. She later contributed to pandemic-related research at STRUBI, Oxford, elucidating the roles of SARS-CoV-2 non-structural membrane proteins 3, 4, and 6. Currently, she is a Group Leader at the Institute of Biochemistry, University of Lübeck, where she also pursues a teaching qualification. Her research contributions include the cryo-EM and X-ray structures of TRPP1, TRPC6, TRPA1, and TMEM45A, alongside work on viral proteins such as CHPV M protein and hHAX-1, advancing understanding of diseases including polycystic kidney disease, focal segmental glomerulosclerosis, cancer, pain, and virus-induced heart failure. Dr. Grieben has published 7 peer-reviewed journal articles, holds an h-index of 3 with 3 citations, and has completed 7 major research projects. She is an active member of GBM and maintains collaborations with academia and industry.

Profile: Scopus

Featured Publications:

Wang, Q., Corey, R. A., Hedger, G., Aryal, P., Grieben, M., Nasrallah, C., Baronina, A., Pike, A. C. W., Shi, J., Carpenter, E. P., & Sansom, M. S. P. (2020). Lipid interactions of a ciliary membrane TRP channel: Simulation and structural studies of polycystin-2. Structure, 28(2), 169-184.e5.

 

 

Amirhosein Kefayat | Cancer Cells | Best Researcher Award

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Dr. Amirhosein Kefayat | Cancer Cells | Best Researcher Award

Edinburgh of University | United Kingdom

Dr. Amirhosein Kefayat is a clinical research fellow at the Institute of Genetics and Cancer, University of Edinburgh, with over fourteen years of dedicated experience in translational and clinical cancer research. Since his early days in medical school, he has pursued a strong passion for advancing oncology through both laboratory and clinical investigations, contributing to more than 60 peer-reviewed publications that have collectively garnered over 2,300 citations, with a Google Scholar H-index of 28. His research spans biomaterials, nanomedicine, wound healing, immunoinformatics, and cancer vaccine design, with several of his papers ranking among the top 1% most-cited in their respective years of publication. Notably, his work on innovative wound dressings, cancer-testis antigen vaccines, and gold nanoclusters for radiosensitization has made significant impacts within the fields of biomaterials and cancer therapeutics. Alongside his research, he is currently advancing his academic qualifications through a Postgraduate Certificate of Academic Practice at the University of Edinburgh and Associate Principal Investigator Training with NIHR. Recognized among the top 0.5% of cancer researchers worldwide, his career reflects a consistent commitment to bridging basic science and clinical application to improve patient care.

Profiles: Google Scholar | Scopus | Orcid

Featured Publications:

Eskandarinia, A., Kefayat, A., Agheb, M., Rafienia, M., Amini Baghbadorani, M., & Navid, S. (2020). A novel bilayer wound dressing composed of a dense polyurethane/propolis membrane and a biodegradable polycaprolactone/gelatin nanofibrous scaffold. Scientific Reports, 10(1), 3063.

Eskandarinia, A., Kefayat, A., Gharakhloo, M., Agheb, M., Khodabakhshi, D., & Rafienia, M. (2020). A propolis enriched polyurethane-hyaluronic acid nanofibrous wound dressing with remarkable antibacterial and wound healing activities. International Journal of Biological Macromolecules, 149, 467–476.

Safavi, A., Kefayat, A., Mahdevar, E., Abiri, A., & Ghahremani, F. (2020). Exploring the out of sight antigens of SARS-CoV-2 to design a candidate multi-epitope vaccine by utilizing immunoinformatics approaches. Vaccine, 38(48), 7612–7628.

Khodabakhshi, D., Eskandarinia, A., Kefayat, A., Rafienia, M., Navid, S., & Karbasi, S. (2019). In vitro and in vivo performance of a propolis-coated polyurethane wound dressing with high porosity and antibacterial efficacy. Colloids and Surfaces B: Biointerfaces, 178, 177–184.

Eskandarinia, A., Kefayat, A., Rafienia, M., Agheb, M., Navid, S., & Ebrahimpour, K. (2019). Cornstarch-based wound dressing incorporated with hyaluronic acid and propolis: In vitro and in vivo studies. Carbohydrate Polymers, 216, 25–35.

Sunila Pradeep | Ovarian Cancer | Women Researcher Award

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Dr. Sunila Pradeep | Ovarian Cancer | Women Researcher Award

Dr. Sunila Pradeep | The Medical College of Wisconsin | United States

Dr. Sunila Pradeep, Ph.D., is an accomplished Associate Professor at the Medical College of Wisconsin, with over two decades of academic and research experience in immunology, oncology, and translational medicine. Originating from India, Dr. Pradeep began her journey in microbiology before delving deep into cancer research. Her multidisciplinary work bridges basic science with clinical relevance, particularly in ovarian and uterine cancers. Having trained in globally recognized institutions like the Weizmann Institute (Israel) and MD Anderson Cancer Center (USA), she has cultivated a robust research portfolio. Her impact in biomedical sciences is well-established. Dr. Pradeep’s ongoing work on extracellular vesicles, tumor microenvironment, and therapy resistance showcases her commitment to solving real-world clinical problems. A recipient of numerous national and international honors, she is a role model for aspiring women in science, blending scientific rigor with compassionate mentorship.

Publication Profile: 

Scopus

Education:

Dr. Sunila Pradeep’s academic path began in India, where she completed her B.Sc. and M.Sc. in Microbiology at Bharathiar University, Coimbatore, Tamil Nadu. Her passion for biomedical sciences led her to pursue a Ph.D. in Immunology at the University of Calicut, Kerala, under the mentorship of Dr. Girija Kuttan, where she began her exploration into natural compounds with anti-cancer properties. Her graduate studies laid a strong foundation in experimental biology and immunomodulation. Eager to expand her research horizons globally, she pursued postdoctoral training at the Weizmann Institute of Science in Israel, and later at the prestigious MD Anderson Cancer Center, Texas, USA, where she transitioned into translational cancer research. This diverse academic journey spanning three countries has given Dr. Pradeep a unique global perspective, rigorous research training, and an innovative approach to solving complex oncological challenges.

Professional Experience:

Dr. Sunila Pradeep has more than 18 years of research experience in oncology and immunology. Her professional career began with a Postdoctoral Fellowship at the Weizmann Institute, where she explored molecular signaling in cancer progression. She then advanced to a key fellowship role at the MD Anderson Cancer Center, focusing on therapeutic resistance in ovarian cancer. Since joining the Medical College of Wisconsin as an Associate Professor, she has established herself as a leading researcher in ovarian tumor microenvironments, metastasis mechanisms, and extracellular vesicle biology. Her role extends beyond research—she is also a dedicated mentor to graduate students and postdocs, and contributes to several multidisciplinary cancer initiatives. Dr. Pradeep’s scientific rigor, grant success, and translational insights have made her a sought-after collaborator. Her efforts to bridge laboratory research with clinical application reflect her commitment to improving outcomes for women suffering from gynecologic cancers.

Awards and Honors:

Dr. Pradeep’s distinguished career has been marked by several prestigious awards. She received the Fr. Gabriel Award from the Amala Institute of Medical Sciences, Kerala, recognizing her excellence in immunology research. During her tenure at MD Anderson Cancer Center, she was honored with the Trainee Excellence Award, reflecting her high-impact work in cancer biology. Her promising contributions to ovarian cancer research earned her the Scholar-in-Training Award from the Marsha Rivkin Center Foundation for Ovarian Cancer Research—a significant achievement for emerging leaders in gynecologic oncology. These accolades underscore her strong scientific foundation, innovation, and leadership in translational oncology. Beyond individual awards, her prolific publication record and active engagement in scientific communities amplify her impact. Dr. Pradeep’s recognition across three continents emphasizes her global footprint and her consistent commitment to advancing women’s health through science.

Research Focus:

Dr. Sunila Pradeep’s research revolves around understanding tumor biology, metastasis, angiogenesis, immunomodulation, and drug resistance in gynecologic cancers, particularly ovarian and uterine cancers. She investigates the role of extracellular vesicles, tumor-derived signals, and the tumor microenvironment in driving cancer progression and therapy evasion. Her lab explores novel biomarkers and targets for overcoming VEGF resistance, improving chemotherapy response, and modulating the immune system to suppress tumor growth. Her translational work includes identifying new combination therapies (e.g., selinexor with eribulin) and examining gut microbiota’s role in estrogen signaling—connecting metabolic and hormonal networks with cancer biology. She is also involved in cutting-edge research on RNA-binding proteins, such as FXR1, and their roles in mRNA translation in cancer. With cross-disciplinary collaborations and NIH-supported studies, her focus bridges fundamental discovery with real-world clinical applications. Her ultimate goal: to make therapies more precise, personalized, and effective for women with cancer.

Publications Top Notes: 

  1. Immunomodulatory and antitumor activity of Piper longum Linn. and piperine

  2. Protective effect of Piper longum fruit ethanolic extract on radiation-induced damages in mice

  3. Expression of VEGF and VEGF receptors in tumor angiogenesis and malignancies

  4. Protective effect of Thuja occidentalis against radiation-induced toxicity in mice

  5. Piper longum inhibits VEGF and proinflammatory cytokines and tumor-induced angiogenesis

  6. Antimetastatic activity of Thuja occidentalis in a mouse model

  7. Inhibition of carcinogenesis by homeopathic drugs

  8. Effect of homeopathic medicines on transplanted tumors in mice

  9. Dynamized preparations in cell culture

  10. Phosphomimetic mutants of PEDF with enhanced antiangiogenic activity as anticancer agents

Conclusion:

Overall, Dr. Sunila Pradeep is highly qualified and a strong candidate for a Best Researcher Award in ovarian cancer research. Her prolific publication record, substantial citation impact, and focus on innovative cancer biology and treatment research provide a solid foundation for recognition. By highlighting her leadership contributions, translational impact, and broader scientific engagement, she can further strengthen her nomination. Her work clearly advances the field of ovarian cancer and serves as a model for impactful biomedical research, making her a deserving contender for such a prestigious award.

 

Yanlan Wang | Cancer Cell Biology | Best Researcher Award

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Dr. Yanlan Wang | Cancer Cell Biology | Best Researcher Award

Dr. Yanlan Wang, Stanford, United States

Dr. Yanlan Wang is a distinguished postdoctoral research fellow at Stanford University’s Department of Pathology. She works in the esteemed Dr. Gerald Crabtree’s lab, where her research revolves around leveraging molecular glues to reprogram cancer drivers and trigger apoptosis. With a strong background in immuno-oncology, antibody engineering, and small molecule therapeutics, Dr. Wang has made significant contributions to targeted cancer therapies. Her interdisciplinary collaborations, notably with Dr. Nathanael Gray’s group, have explored the role of transcription factor complex-inducing compounds (TCIPs) in MLL-rearranged leukemia. Dr. Wang brings a rich international research experience from China and the U.S., with a career spanning translational medicine, biotechnology innovation, and academic excellence. She is known for her rigorous approach to scientific inquiry, collaborative spirit, and prolific publication record. Her passion for understanding and overcoming the mechanisms of cancer resistance positions her as a future leader in oncology drug development and precision medicine.

Publication Profile: 

Scopus

✅ Strengths for the Award:

  1. Outstanding Research Focus
    Dr. Wang’s work on molecular glues and transcription factor modulators represents cutting-edge approaches in cancer therapy, especially in targeting previously undruggable pathways.

  2. High Impact Publications
    With multiple first-author and co-corresponding author papers (e.g., J Immunol Methods 2025, Leukemia & Lymphoma 2020, Clin Pharmacol Ther 2021), Dr. Wang has demonstrated a strong track record in both fundamental and translational cancer research.

  3. Innovation & Translational Impact
    Her efforts in bispecific antibody engineering, IL-15 therapeutics, and AKR1C3-targeted prodrugs show clear applications in oncology drug development, bridging the lab and clinic.

  4. Prestigious Collaborations
    Collaborating with renowned researchers such as Dr. Gerald Crabtree and Dr. Nathanael Gray at Stanford indicates high confidence and integration in world-class research circles.

  5. Recognition & Awards
    She has received the Coxe Fellowship at Stanford and multiple merit-based scholarships, highlighting academic excellence and innovation.

  6. Leadership and Multidisciplinary Skills
    Dr. Wang has led several projects, authored high-level papers, and mentored junior researchers, showcasing both technical and leadership capability.

🔄 Areas for Improvement:

  1. Greater International Presentation Exposure
    Although she has strong publication credentials, more visibility through international oral presentations, keynote addresses, or panel roles would amplify her leadership profile.

  2. Independent Grant Record
    While she is currently in a postdoctoral role, seeking independent funding (e.g., K99/R00, early-career PI grants) would position her more competitively for independent investigator status.

  3. Patent or Commercial Translation
    Given the translational nature of her work, pursuit of intellectual property filings or biotech partnerships would further highlight impact.

🎓 Education:

Dr. Yanlan Wang began her academic journey at Xiangya School of Medicine, Central South University, where she earned her MBBS (M.D. equivalent) in June 2012. She continued at The Second Xiangya Hospital for her clinical residency, completing her M.S. in June 2015. Her pursuit of scientific excellence led her to earn a doctorate (M.D. equivalent to PhD) from Sun Yat-sen University in June 2018, with a research focus on microbial immunology and tumor biology. This diverse educational background gave her a solid foundation in both clinical medicine and biomedical research, allowing her to bridge translational gaps in cancer research. Her early training emphasized immunotherapy, molecular biology, and oncology, all of which paved the way for her postdoctoral work in cutting-edge labs. Her education reflects a consistent upward trajectory, marked by prestigious institutions, interdisciplinary training, and a seamless integration of clinical and scientific disciplines.

🔬 Experience:

Dr. Yanlan Wang is currently a postdoctoral research fellow in Dr. Gerald Crabtree’s lab at Stanford University, where she focuses on manipulating cancer cell pathways using molecular glues. Her prior research in China included pivotal roles in biotechnology innovation, including bispecific antibody engineering, prodrug design, and immune-oncology drug development. She has also collaborated extensively with Dr. Nathanael Gray’s lab at Stanford, exploring the therapeutic potential of TCIPs in leukemia. Dr. Wang’s hands-on experience includes multiplex screening platforms, flow cytometry, in vivo tumor models, and translational immunotherapy development. Over the years, she has taken leadership roles in preclinical projects, manuscript authorship, and international scientific presentations. Her diverse roles—from clinical residency to laboratory innovation—reflect her capability to translate complex scientific findings into therapeutic strategies. Dr. Wang has also mentored junior researchers and worked across multiple disciplines, underscoring her adaptability, leadership potential, and deep commitment to cancer research.

🏅 Awards and Honors:

Dr. Yanlan Wang’s excellence has been recognized through several prestigious awards. At Stanford, she received the Coxe Fellowship in 2021, honoring outstanding postdoctoral researchers. During her doctoral training, she earned the Special Award of Merit for the BJ-001 Project at BJ Bioscience Inc. in 2019 for her impactful translational research. Her academic merit was consistently acknowledged through the Bidi Scholarship (2016–2017) and Daxiang Scholarship (2015–2016) at Sun Yat-sen University. These honors underscore her commitment to scientific excellence, innovation, and translational impact in oncology and immunotherapy. Her ability to receive awards across both academic and industrial settings highlights her versatility and the real-world relevance of her work. These distinctions serve as a testament to her leadership in cancer drug development, collaborative effectiveness, and contribution to next-generation therapeutic discoveries.

🔍 Research Focus:

Dr. Yanlan Wang’s research lies at the intersection of cancer biology, molecular pharmacology, and immunotherapy. At Stanford, she investigates how molecular glues can be used to hijack cancer drivers and activate apoptosis, offering a novel route for targeted cancer therapies. Her work involves multiplex molecular glue screening, understanding protein degradation pathways, and designing synthetic lethality strategies. In collaboration with Dr. Nathanael Gray, she is also studying Transcription factor Complex-Inducing Compounds (TCIPs) for the treatment of MLL-rearranged leukemia, a particularly aggressive form of blood cancer. Prior to this, her research focused on bispecific antibodies, prodrugs, and IL-15 based immunotherapeutics, with a vision to decouple efficacy from toxicity. Through a blend of basic science and translational applications, she aims to rewire oncogenic signaling pathways and enhance anti-tumor immunity. Her research combines drug discovery, systems biology, and precision oncology, pushing the boundaries of targeted cancer treatment.

📚 Publications Top Notes:

  1. 🔬 Quantitative flow cytometry using quantitative streptavidin-protein G-biotin beads (qBeads) – J Immunol Methods, 2025

  2. 🧬 A Bivalent Molecular Glue Linking Lysine Acetyltransferases to Oncogene-directed Cell Death – Cell (revising)

  3. 💉 Enhance IL15 anti-tumor efficacy by inhibiting its negative feedback mechanism – (in preparation)

  4. ⚛️ Decouple the toxicity and efficacy of BJ-001, an integrin targeting IL-15 – AACR Abstract, 2019

  5. 🔄 Decoupling the toxicity and efficacy of immunotherapeutics – SITC Abstract, 2019

  6. 🧪 An AKR1C3-specific prodrug with potent anti-tumor activities against T-ALL – Leukemia & Lymphoma, 2020

  7. 🧫 A novel AKR1C3 specific prodrug TH3424 with potent anti-tumor activity in liver cancer – Clin Pharmacol Ther, 2021

  8. 🧲 A GPC3-targeting Bispecific Antibody, GPC3-S-Fab, with Potent Cytotoxicity – J Vis Exp, 2018

  9. 🧠 Identification of anti-CD16a single domain antibodies and their application in bispecific antibodies – Cancer Biol Ther, 2020

  10. 🧿 Bp-Bs, a novel T-cell engaging bispecific antibody with biparatopic Her2 binding – Mol Ther Oncolytics, 2019

  11. 🧰 A novel multi-functional anti-CEA-IL15 molecule displays potent anti-tumor activities – Drug Des Devel Ther, 2018

  12. 🧠 A single domain based anti-Her2 antibody has potent anti-tumor activities – Transl Oncol, 2018

🧾 Conclusion:

Dr. Yanlan Wang is highly deserving of the Best Researcher Award. Her contributions to cancer therapeutics through novel molecular approaches, her collaborations with globally renowned labs, and her publication record reflect a researcher of exceptional caliber and promise. With a deep understanding of tumor biology, a commitment to innovation, and a growing leadership presence in oncology research, she is not only suitable for the award but stands as a strong role model for future biomedical researchers.

Sen Wang | Cancer Cell Biology | Best Researcher Award

Published on by Cell Biologist

Ms. Sen Wang | Cancer Cell Biology | Best Researcher Award

Ms. Sen Wang , Affiliated Hospital of Jining Medical College , China

Dr. Wang Sen is an accomplished researcher and Deputy Chief Technician at the Affiliated Hospital of Jining Medical University. With a Ph.D. in Pharmaceutical Engineering and a postdoctoral fellowship at Shandong University of Traditional Chinese Medicine, he has developed deep expertise in molecular oncology, tumor microenvironments, and translational medicine. His career spans over a decade, marked by significant research in gastrointestinal and renal cancers, exploring mechanisms of autophagy, endothelial dysfunction, and tumor angiogenesis. Dr. Wang has led and contributed to several prestigious research projects, including National Natural Science Foundation grants. He has published in high-impact journals and holds patents that support translational applications in oncology. Recognized by peers and institutions alike, he received the Shandong Medical Association Youth Science and Technology Award. His work continues to push boundaries in cancer research, demonstrating strong scientific leadership and a commitment to improving therapeutic strategies.

Publication Profile: 

Scopus

✅ Strengths for the Award

  1. Extensive Research Background
    Dr. Wang has demonstrated a consistent and deep involvement in cutting-edge cancer research, especially focusing on tumor microenvironment regulation, autophagy, and angiogenesis—key areas in translational oncology.

  2. Prolific Publication Record
    He is the sole first author of several papers published in high-impact journals like British Journal of Cancer, Cell Death & Disease, and Scientific Reports. These contributions indicate scientific independence and strong writing and experimental skills.

  3. Leadership in Funded Projects
    He has served as Principal Investigator (PI) on multiple prestigious projects, including the NSFC Youth Fund and China Postdoctoral Foundation grants, which testifies to his research leadership and capability in securing competitive funding.

  4. Innovative Impact through Patents
    Dr. Wang is a co-inventor of three Chinese patents, including a novel therapeutic application of MT1G in renal cancer—highlighting a strong translational component in his research.

  5. Academic Awards and Recognition
    His receipt of the Shandong Medical Association Youth Science and Technology Award (Second Prize) in 2024 is an external validation of his scientific excellence at the provincial level.

  6. Collaborative and Interdisciplinary Approach
    His co-authorship with experts across molecular biology, pharmacology, and clinical research demonstrates a collaborative nature crucial for multidisciplinary medical advancements.

📈 Areas for Improvement

  1. International Recognition
    While Dr. Wang’s work is commendable within China, increasing collaboration or recognition on an international level (e.g., international conferences, global research networks) would further elevate his research visibility.

  2. Citations and Real-world Applications
    Some of his recent papers have not yet garnered citations. Continued dissemination, follow-up studies, and clinical application testing will help boost impact.

  3. Expanded Mentorship Role
    There is limited information on his mentorship of young scientists or PhD students. Strengthening academic mentorship could broaden his influence within the scientific community.

🎓 Education:

Dr. Wang Sen has pursued a comprehensive academic path in life sciences and medical research. He earned his Ph.D. in Pharmaceutical Engineering from Chongqing Medical University (2016–2019), following a Master’s degree in Biochemistry and Molecular Biology at the same institution (2013–2016). His foundational training began with a Bachelor’s degree in Biological Engineering from Jining University (2009–2013), where he laid the groundwork for his interest in molecular biology and drug development. His doctoral and master’s work focused on cancer biology, signaling pathways, and translational medicine—preparing him for cutting-edge postdoctoral research at Shandong University of Traditional Chinese Medicine (2022–2024). This academic journey has equipped him with strong theoretical and experimental skills that he applies in both clinical and laboratory settings.

🧪 Experience:

Dr. Wang Sen currently serves as Deputy Chief Technician at the Affiliated Hospital of Jining Medical University (since Nov 2024). Prior to this, he held the role of Chief Technician (2019–2024) at the same hospital, where he led several translational cancer research projects. His responsibilities include designing experimental protocols, overseeing clinical collaboration, and mentoring junior researchers. His postdoctoral research (2022–2024) at Shandong University of Traditional Chinese Medicine focused on tumor angiogenesis and metabolic regulation. Throughout his academic and professional journey, he has shown a keen interest in understanding cancer cell signaling, tumor-endothelial interactions, and the development of therapeutic targets. His multidisciplinary expertise makes him a vital contributor to collaborative projects in molecular medicine and drug discovery.

🏆 Awards and Honors:

Dr. Wang Sen’s contributions to medical research have earned him notable recognition. In 2024, he received the Shandong Medical Association Youth Science and Technology Award (Second Prize), celebrating his innovative work in cancer biology. He is also a co-inventor on three Chinese patents, including the application of MT1G protein inhibitors for renal cancer and methods related to small molecule metabolite ligands and exosome preparation. These patents demonstrate his commitment to translational research and innovation in therapeutic development. Additionally, his participation in collaborative high-impact publications and national grants has solidified his reputation as a rising leader in biomedical sciences. His academic integrity, technical depth, and consistent contributions to cutting-edge research make him an ideal candidate for recognition through prestigious awards like the Best Researcher Award.

🔬 Research Focus:

Dr. Wang Sen’s research centers on tumor microenvironment regulation, angiogenesis, autophagy, and tumor stem cell interactions, with a strong focus on gastrointestinal and renal cancers. His work often integrates cellular signaling, exosome biology, and gene expression regulation to understand cancer progression and metastasis. Key interests include pathways involving INSR/FGF5/ADRB2, ALDOC, and MT1G, which he investigates for their roles in tumor metabolism and vascular dynamics. Dr. Wang combines clinical relevance with basic science, aiming to translate molecular findings into diagnostic tools or therapeutic targets. His innovative studies on betulinic acid, p53-mediated pathways, and epigenetic modifications contribute to the broader field of precision oncology. His interdisciplinary approach—bridging pharmacology, molecular biology, and clinical application—positions him as a dynamic researcher capable of advancing medical science.

📚 Publications Top Notes:

  1. 📘 MT1G induces lipid droplet accumulation through H3K14 trimethylation in renal cancer, British Journal of Cancer, 2024 – 🥇 Sole First Author

  2. 📗 p53-mediated autophagy protects against betulinic acid-induced apoptosis in colorectal cancer, Cell Death & Disease, 2017 – 🥇 Sole First Author

  3. 📕 FOXS1 is regulated by GLI1/miR-125a-5p, promotes proliferation and EMT in gastric cancer, Scientific Reports, 2019 – 🥇 Sole First Author

  4. 📙 Identification of the human HAS3 promoter region, Biochemical and Biophysical Research Communications, 2015 – 🥇 Sole First Author

  5. 📓 Betulinic acid induces G2/M arrest via MT1G in colon cancer cells, Heliyon, 2024 – 👥 Co-First Author

  6. 📔 PCDH17 induces colorectal cancer metastasis by disrupting vascular barriers, Cell Death and Disease, 2025 – 🧬 Contributor

  7. 📒 OX40 activation drives tumor escape via S1P/YAP angiogenesis, Journal of Clinical Investigation, 2025 – 🧬 Contributor

🧾 Conclusion:

Dr. Wang Sen is a highly qualified and worthy candidate for the Best Researcher Award. His impressive portfolio—spanning publications, funded projects, patents, and recognized awards—shows that he is not only producing important knowledge but also moving toward real-world application in cancer therapeutics. With continued focus on global engagement and translational outcomes, he is poised to become a leading figure in molecular oncology. His scientific rigor, innovation, and leadership embody the spirit of this award.

Weifen Zhang | Cancer Cell Biology | Best Researcher Award

Published on by Cell Biologist

Prof. Weifen Zhang | Cancer Cell Biology | Best Researcher Award

Prof. Weifen Zhang , Shandong Second Medical University , China

Professor Weifen Zhang is a renowned scientist in pharmaceutical sciences, serving as a Professor at the School of Pharmacy, Shandong Second Medical University. She also directs the Shandong Engineering Research Center for Intelligent Materials and Regenerative Medicine and the Pharmaceutical Experimental Teaching Center. With over 50 SCI-indexed publications and 27 national and international patents, her contributions have significantly influenced the development of targeted drug delivery systems and smart biomaterials. A recipient of the State Council Special Allowance and recognized as a Shandong Provincial Outstanding Expert, Professor Zhang combines academic excellence with practical innovation. She has led and collaborated on numerous national-level research projects, focusing on novel therapeutic strategies for cancer, regenerative medicine, and nano-drug technologies. Additionally, she plays a prominent role in scientific publishing as a guest editor and reviewer for leading journals. Her dedication to interdisciplinary research continues to shape the future of pharmaceutical technology.

Publication Profile: 

Scopus

✅ Strengths for the Award:

  1. 📚 High Research Productivity: Over 50 SCI-indexed publications in high-impact journals such as ACS Applied Materials & Interfaces, Journal of Biomedical Nanotechnology, and Science China Materials.

  2. 💡 Innovation & Intellectual Property: Holds 27 national and international patents, showing a strong translation of academic work into real-world applications.

  3. 🔬 Research Focus & Impact: Cutting-edge work in targeted drug delivery systems, intelligent biomaterials, and regenerative medicine, especially impactful in oncology.

  4. 🎯 Project Leadership: Principal Investigator for multiple nationally funded projects, managing significant funding amounts and driving original discoveries.

  5. 🌐 Academic Influence: Serves as a guest editor and reviewer for leading scientific journals, contributing to quality control and peer knowledge advancement.

  6. 📖 Educational Impact: Contributions to national-level textbooks like Pharmaceutics and Pharmaceutical English highlight her role in shaping future pharmaceutical education.

  7. 🤝 Industry Collaboration: Active collaborations with companies like NOIMAIER (Shandong) Medical Technology Co., Ltd, demonstrating practical application and outreach.

⚠️ Areas for Improvement:

  1. 🌍 Global Outreach: While her influence is strong nationally, increased participation in international conferences, collaborations, and global visibility would further elevate her stature.

  2. 🎙️ Public Engagement: Enhanced involvement in science communication, including talks, public articles, or media, could broaden her societal impact.

  3. 🌐 Online Presence: A more visible online research profile (e.g., Google Scholar, ResearchGate, LinkedIn) could help in networking and research dissemination globally.

🎓 Education:

Professor Weifen Zhang received comprehensive training in pharmaceutical sciences, culminating in a doctorate in pharmacy or a related biomedical field (specific degree and institution not provided in the current profile). Her academic journey has been deeply rooted in advancing applied pharmaceutical research, especially in the field of drug delivery and intelligent materials. Her educational background laid the foundation for her specialization in nanoformulations, regenerative medicine, and drug resistance reversal. Professor Zhang has supplemented her academic credentials with continued professional development through her work with major national science foundations and governmental innovation programs. Her commitment to combining traditional pharmaceutical training with cutting-edge material science has enabled her to become a leader in translational research. Although the detailed degrees and institutions are not specified, her track record in high-impact research, publications, and academic leadership reflects a strong and diverse educational background.

🧪 Experience:

Professor Zhang brings over two decades of experience in pharmaceutical sciences, nanomedicine, and biomaterial engineering. She has served in multiple leadership roles, including Director of both the Shandong Engineering Research Center for Intelligent Materials and Regenerative Medicine and the Pharmaceutical Experimental Teaching Center at Shandong Second Medical University. As Principal Investigator on numerous high-profile projects funded by the National Natural Science Foundation of China and regional innovation programs, she has demonstrated excellence in both basic and translational research. Her industrial collaborations and consultancy projects, such as those with NOIMAIER Medical Technology, reflect her ability to translate scientific innovation into practical solutions. Her experience is also reflected in her active editorial and peer review contributions to top-tier journals, as well as her involvement in educational contributions through national textbook projects. Her academic, industrial, and clinical translational experiences make her a uniquely qualified and impactful researcher.

🔬 Research Focus:

Professor Weifen Zhang’s research is at the forefront of targeted drug delivery, intelligent biomaterials, and regenerative medicine. Her primary scientific focus involves developing novel nanoparticle-based platforms to improve therapeutic outcomes in diseases such as non-small cell lung cancer. She has led pioneering studies in dual-drug synergistic delivery, utilizing agents like quercetin and paclitaxel, aimed at overcoming drug resistance. Her lab also explores smart, biodegradable materials, such as Bletilla striata polysaccharide microneedles, for innovative therapeutic applications including hair regrowth and skin regeneration. In regenerative medicine, she is advancing bionic materials, such as mineralized collagen scaffolds, for orthopedic and dental use. Additionally, she works on plant-derived compounds, contributing to both pharmaceutical and agricultural solutions. Through interdisciplinary approaches, including nanotechnology, immunology, and pharmacokinetics, Professor Zhang’s work is positioned to influence both academic research and clinical practice. Her vision continues to shape the field of personalized and precision medicine.

📚 Publications Top Notes:

  1. 📌 Bletilla striata polysaccharide-based dissolving microneedle patch integrated with nanoparticles for promoting hair regrowth

  2. 🧱 Composite scaffolds based on egg membrane and eggshell-derived inorganic particles promote soft and hard tissue repair

  3. 💉 Efficient chemo-immunotherapy leveraging minimalist electrostatic complex nanoparticle as “in situ” vaccine integrated tumor ICD and immunoagonist

  4. 🌿 A Chinese drug-compatibility-based approach to purslane hydrogels for acute eczema therapy

  5. 🔬 Dynamic Covalent Bond-Based Nanoassembly of Curcumin to Enhance the Selective Photothermal Therapy for Tumor Treatment

  6. 🧵 Multifunctional Nanofiber Membranes Constructed by Microfluidic Blow-Spinning to Inhibit Scar Formation at Early Intervention Stage

  7. 📄 Corrigendum to “Synergistically enhanced cancer immunotherapy by combining protamine-based nanovaccine with PD-L1 gene silence nanoparticle”

  8. 💉 Minimalist “in situ” tumor vaccine leveraging versatile dendrimer nanoplatform coordinated ICD and immunoagonist for boosted chemoimmunotherapy

  9. 🧬 A minimalist cancer cell membrane-shielded biomimetic nanoparticle for nasopharyngeal carcinoma active-targeting therapy

  10. ⚗️ Biodegradable Manganese-Containing Mesoporous Silica Nanoparticles for Precisely Controlled Quercetin Delivery

 

📌 Conclusion:

Professor Weifen Zhang demonstrates exceptional qualifications for the Best Researcher Award. Her deep scientific contributions, robust patent portfolio, influential publications, and national leadership in pharmaceutical innovation mark her as a leader in biomedical research. With a few enhancements in global visibility and science communication, her already impressive profile could reach even greater heights.

Huizheng Hu | Cancer Cell Biology | Best Researcher Award

Published on by Cell Biologist

Ms. Huizheng Hu | Cancer Cell Biology | Best Researcher Award

Ms. Huizheng Hu , Nuclear Industry 215 Hospital of Shaanxi Province , China

Dr. Huizheng Hu is a distinguished medical scientist and Director of the Laboratory Department at the Nuclear Industry 215 Hospital of Shaanxi Province, China. As an Associate Professor, Dr. Hu has made significant strides in the fields of tumor cell biology and microbial drug resistance. With a strong foundation in pathogenic microbiology and translational medicine, he integrates clinical practice with cutting-edge laboratory research. He has published six SCI-indexed papers and received numerous accolades, including multiple awards from the Xianyang Science and Technology Progress Committee and recognition as an “Outstanding Individual of Shaanxi Province.” His leadership in research projects on papillary thyroid carcinoma (PTC) and ongoing collaborations with Northwest University further reflect his dedication to scientific advancement. Known for his innovation, expertise, and commitment to healthcare, Dr. Hu is a leading figure bridging oncology and infectious disease research.

Publication Profile: 

Scopus

✅ Strengths for the Award:

  1. Research Excellence:
    Dr. Hu has published six peer-reviewed SCI-indexed papers in the fields of oncology and microbiology—two globally significant research domains.

  2. Leadership in Research Projects:
    Currently leading three active research projects on papillary thyroid carcinoma (PTC) and has successfully secured six competitive research grants, reflecting his project management and funding acquisition capabilities.

  3. Innovative Interdisciplinary Work:
    His translational research bridges tumor biology and infectious diseases, an emerging and impactful cross-disciplinary niche in medical science.

  4. Recognized Expertise:
    Awarded multiple prestigious honors including:

    • Third Prize from the Nuclear Industry Geological Exploration Bureau

    • Seven awards from the Xianyang Science and Technology Progress Committee

    • Named a “Three-Five Talent” and “Outstanding Individual of Shaanxi Province”

  5. Academic Collaborations:
    Active collaboration with Professor Li Zheng’s team at Northwest University, showcasing a commitment to scientific cooperation.

🔧 Areas for Improvement:

  1. Global Visibility:
    While regionally recognized, Dr. Hu’s international presence could be enhanced by:

    • Publishing in higher-impact global journals

    • Participating in global scientific conferences or forums

  2. Editorial and Membership Roles:
    Expanding into editorial boards or joining professional organizations would further validate and amplify his professional stature in the scientific community.

  3. Digital/Research Profiles:
    Maintaining updated digital research profiles (e.g., Google Scholar, ResearchGate) and citation metrics would strengthen the transparency and accessibility of his academic output.

🎓 Education:

Dr. Huizheng Hu holds an advanced academic background specializing in medical sciences with a focus on tumor biology and microbiology. He earned his medical degree and pursued postgraduate training in pathogenic microbiology, acquiring both clinical and research experience. His academic training includes a strong emphasis on experimental design, molecular biology, and translational research. Dr. Hu further refined his expertise during specialized programs and workshops that focused on cancer biology, microbial resistance mechanisms, and diagnostic laboratory technologies. This rigorous educational foundation enabled him to become an expert in handling infectious disease diagnostics and tumor pathology. His education was also complemented by institutional mentorships and collaborations that contributed to his development as an academic and professional leader in his field. As an academic, he continues to integrate his theoretical training into real-world clinical scenarios, enhancing both patient outcomes and scientific understanding.

💼 Professional Experience:

With over a decade of experience in clinical and laboratory medicine, Dr. Huizheng Hu currently serves as the Director of the Laboratory Department at Nuclear Industry 215 Hospital in Shaanxi Province. As an Associate Professor, he has led various research initiatives and clinical programs, particularly in oncology and microbiology. His role involves overseeing diagnostics, laboratory quality control, and supervising research staff. Dr. Hu has been a key figure in managing multidisciplinary projects focused on tumor biology and microbial resistance. He has secured six competitive research grants and is actively involved in national and regional research programs. His accolades include multiple awards for scientific innovation and academic leadership, such as the “Leading Talent in Scientific and Technological Innovation” title. Dr. Hu has also been recognized for his contributions to public health and research excellence through provincial honors. His practical experience strengthens his role as both a healthcare provider and scientific innovator.

🔬 Research Focus:

Dr. Huizheng Hu’s research focuses on two core areas: tumor cell biology and microbial drug resistance mechanisms. His studies aim to understand the cellular and molecular dynamics of cancers, especially papillary thyroid carcinoma (PTC), and how microbial pathogens adapt to drugs in clinical settings. His translational research bridges oncology with infectious disease treatment, offering new perspectives on personalized medicine. Currently, Dr. Hu is leading three major projects targeting PTC progression and diagnostics. Additionally, he collaborates with Professor Li Zheng’s team at Northwest University to explore mechanisms of microbial resistance, with a particular emphasis on hospital-acquired infections. His work integrates clinical microbiology, molecular biology, and pathology, aiming to develop targeted therapies and improve diagnostic accuracy. Through extensive laboratory work, real-world clinical application, and collaborative research, Dr. Hu is actively contributing to both cancer and infectious disease innovation, striving for improved patient care outcomes and global health advancements.

📚 Publications Top Notes:

  • 🦠📊 Analysis of infection indicators and risk factors for influenza A after the COVID-19 pandemic – New Microbiologica, 2024

  • 🔬🧬 Molecular pathways in papillary thyroid carcinoma: A focus on tumor microenvironment interactions

  • 💊🧫 Mechanisms of microbial resistance to last-line antibiotics in hospital pathogens

  • 🧪👨‍⚕️ Diagnostic advancements in thyroid cancer: A laboratory-based approach

  • 🧻⚗️ The interplay between microbiota and immune modulation in cancer patients

  • 🧬🧪 Comparative study of PTC biomarkers using immunohistochemical techniques

🧾 Conclusion:

Dr. Huizheng Hu is a highly suitable candidate for the Best Researcher Award. His leadership in research, strong publication record, and numerous regional accolades demonstrate sustained excellence in scientific innovation. While expanding international engagement could further elevate his profile, his ongoing contributions to cancer and microbiology research already reflect a distinguished career deserving of recognition at a global level.

Dengyong Zhang | Cancer Cell Biology | Best Researcher Award

Published on by Cell Biologist

Prof. Dengyong Zhang | Cancer Cell Biology | Best Researcher Award

Prof. Dengyong Zhang , The First Affiliated Hospital of Bengbu Medical university , China

Zhang Deng Yong is a highly accomplished medical professional and researcher specializing in hepatocellular carcinoma and cholangiocarcinoma. Born in Liu’an, Anhui Province, China, in 1989, he currently works as an attending doctor at the First Affiliated Hospital of Bengbu Medical College. Dr. Zhang earned his Bachelor’s and Master’s degrees from Bengbu Medical College and is currently pursuing a Doctor’s degree at Anhui Medical University. He is also a visiting scholar at MD Anderson Cancer Center. With an extensive portfolio of research, Dr. Zhang is known for his significant contributions to the study of cancer biology, particularly in liver and biliary cancers. His commitment to medical research and patient care positions him as a key figure in the field of oncology.

Publication Profile:

Scopus

Strengths for the Award:

Dr. Zhang Deng Yong exhibits exceptional skills and commitment to the field of medical research, particularly in oncology. His advanced academic qualifications (Doctor’s degree from Anhui Medical University and a Master’s degree from Bengbu Medical College) provide a solid foundation for his innovative research. He has made significant contributions to understanding the molecular mechanisms underlying various cancers, especially hepatocellular carcinoma and cholangiocarcinoma, as evidenced by his numerous impactful publications. His collaborative work, demonstrated through his visiting scholar position at the MD Anderson Cancer Center, speaks to his ability to engage in high-caliber research environments.

Areas for Improvement:

While Dr. Zhang’s research portfolio is robust, expanding his involvement in interdisciplinary research or establishing collaborations beyond oncology could open new avenues in cancer treatment and prevention. Additionally, enhancing his focus on translational medicine could bridge the gap between laboratory research and clinical application.

Education:

Dr. Zhang Deng Yong’s academic journey began at Bengbu Medical College, where he earned his Bachelor’s degree in Medicine (2007-2012). He furthered his education with a Master’s degree in Surgery from the same institution (2012-2015). Currently, he is pursuing a Doctor’s degree at Anhui Medical University (2021-2024), specializing in oncology and cancer treatment. His dedication to academic excellence is reflected in his continued involvement in both teaching and advanced clinical research. In addition to his formal education, Dr. Zhang has participated in various international conferences and academic collaborations, further strengthening his expertise in medical research and surgery.

Experience:

Dr. Zhang has a solid background in clinical practice and research. Since 2016, he has served as an attending doctor at the First Affiliated Hospital of Bengbu Medical College, where he specializes in oncology and surgery. He also worked as a resident at Lu’an Traditional Chinese Medicine Hospital from 2015 to 2016. In 2022, Dr. Zhang had the opportunity to enhance his research experience as a visiting scholar at MD Anderson Cancer Center, a leading institution in cancer research. His clinical experience, combined with his academic training, allows him to offer patients the highest standard of care while contributing to groundbreaking cancer research. His expertise in hepatocellular carcinoma and cholangiocarcinoma has made him a sought-after expert in his field.

Awards and Honors:

Dr. Zhang Deng Yong’s commitment to research and medicine has earned him various recognitions and funding opportunities. He was awarded a Natural Science Fund of Anhui Province support from 2018 to 2020. Additionally, his work has been widely recognized in the academic community, where he has acted as a reviewer for multiple prestigious journals such as Oncology Reports, Molecular Medicine Reports, Oncology Letters, and Experimental and Therapeutic Medicine. These roles reflect his standing in the medical and scientific community. His involvement in clinical and research innovation has placed him at the forefront of oncology research, especially in the areas of hepatocellular carcinoma and cholangiocarcinoma.

Research Focus:

Dr. Zhang’s research primarily focuses on cancer biology, particularly hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA). He is dedicated to understanding the molecular mechanisms behind cancer progression, immune responses, and therapeutic resistance. His work includes investigating the roles of various genetic and epigenetic factors in the development of liver and biliary cancers, as well as identifying potential biomarkers for early diagnosis and prognosis. Dr. Zhang’s research extends to exploring novel therapeutic approaches, including immunotherapy, targeted therapies, and the use of CRISPR technology. His publications also delve into the immune landscape and molecular pathways that influence cancer progression, with an emphasis on improving patient outcomes through precision medicine. His passion for cancer research and patient care continues to drive his work and innovations in the field.

Publications Top Notes:

  1. Immunosenescence and immunotherapy in elderly patients with hepatocellular carcinoma 🧬🦠

  2. USP1 promotes cholangiocarcinoma progression by deubiquitinating PARP1 to prevent its proteasomal degradation 🧬⚡

  3. CRISPR screening identifies BET and mTOR inhibitor synergy in cholangiocarcinoma through serine glycine one carbon 🔬🧬

  4. MiR-186-5p prevents hepatocellular carcinoma progression by targeting methyltransferase-like 3 that regulates m6A-mediated stabilization of follistatin-like 5 💡🧬

  5. The COL7A1/PI3K/AKT axis regulates the progression of cholangiocarcinoma 🔬🧬

  6. Integrative analysis of bulk and single-cell transcriptomic data reveals novel insights into lipid metabolism and prognostic factors in hepatocellular carcinoma 🧬💡

  7. HSDL2 knockdown promotes the progression of cholangiocarcinoma by inhibiting ferroptosis through the P53/SLC7A11 axis ⚡🔬

  8. Application of mesohepatectomy with caudate lobectomy for the treatment of type III–IV hilar cholangiocarcinoma: a single-center retrospective study 🏥📑

  9. Prognostic model for hepatocellular carcinoma based on anoikis-related genes: immune landscape analysis and prediction of drug sensitivity 🔬💉

  10. Bile metabolites as diagnostic biomarkers for perihilar cholangiocarcinoma 🧬💡

Conclusion:

Dr. Zhang Deng Yong’s expertise in cancer research, particularly his contributions to hepatocellular carcinoma and cholangiocarcinoma, places him as a strong contender for the Research for Best Researcher Award. His dedication to advancing medical knowledge, coupled with his impressive list of publications and international collaboration, makes him an invaluable asset to the scientific community. With continued growth in clinical application, Dr. Zhang is poised for further recognition and impactful contributions to medical research.

 

 

 

Dominique Heymann | Cancer Cell Biology | Best Researcher Award

Published on by Cell Biologist

Prof. Dr. Dominique Heymann | Cancer Cell Biology | Best Researcher Award

Prof. Dr. Dominique Heymann , Nantes Université, CNRS, Institut de Cancérologie de l”Ouest , France

Professor Dominique Heymann is a highly esteemed academic and clinician, specializing in histology, embryology, and oncology. He is a Professor at Nantes University, France, and a Hospital Practitioner at the ICO Cancer Centre. With a wealth of experience in bone oncology and cancer research, he is also an Honorary Professor at the University of Sheffield, UK. His expertise spans from cell biology to immunology and biochemistry, and he is dedicated to advancing cancer research, particularly in the field of bone tumors and osteosarcoma. With numerous publications to his name and contributions to the global scientific community, Professor Heymann is recognized for his groundbreaking work in cell signaling and tumor progression. He is a valued researcher in the oncology community, with a strong focus on developing innovative therapies for cancer treatment.

Publication Profile:

Google Scholar

Strengths for the Award:

Professor Dominique Heymann is a distinguished figure in the field of oncology, particularly bone oncology, with a strong focus on the molecular mechanisms of bone tumors like osteosarcoma. His academic and clinical roles at the University of Nantes and the ICO Cancer Centre underscore his leadership in research and patient care. He has contributed significantly to understanding tumor biology, bone remodeling, and regenerative medicine, making him a highly respected expert in these fields. His research addresses crucial topics such as circulating tumor cells, targeted therapies, and the development of new anticancer agents, all of which are of immense value to advancing cancer treatment. With multiple publications in prestigious journals, including studies on novel therapies and molecular pathways in cancer progression, Professor Heymann has demonstrated exceptional scientific rigor. His global collaborations and recognition further establish him as a leading researcher in cancer biology and oncology.

Areas for Improvements:

Despite his numerous contributions, there are a few areas where Professor Heymann’s research could evolve. While he has made notable strides in cancer treatment and bone oncology, expanding research into more personalized medicine approaches and exploring the integration of AI and machine learning in predictive oncology could enhance the applicability of his findings. Furthermore, increasing collaborative efforts with international interdisciplinary teams could yield broader insights, especially in rare cancers and metastasis research. Developing a more extensive outreach to clinical trials and collaborations in broader regions may also allow for faster translation of his research into practice.

Education:

Professor Heymann began his academic journey at Paris VII University, where he earned a Master’s degree in Cell Biology in 1991. His PhD in Cell Biology and Immunology was completed at Nantes University in 1995, a pivotal moment in his career. Further expanding his knowledge, he pursued research management abilities and a deeper focus on Biochemistry and Cell Biology at Nantes University in 1998. He also received specialized certification in Histology from Nantes University in 1999 and later completed the required authorizations for animal experimentation in 2003 and 2016. Throughout his academic career, Professor Heymann has continually updated his qualifications, ensuring his expertise remains at the cutting edge of medical and biological sciences. His academic foundation has underpinned his significant contributions to cancer research, with a strong emphasis on bone oncology and regenerative medicine.

Experience:

Professor Dominique Heymann has an extensive and diverse career spanning several decades in both academic and clinical settings. Currently, he serves as a Professor of Histology/Embryology at Nantes University and as a Hospital Practitioner at the ICO Cancer Centre, where he is instrumental in patient care and research. His professional trajectory includes significant roles in oncology, particularly focused on bone tumors, osteosarcoma, and regenerative medicine. As an Honorary Professor at the University of Sheffield, he extends his influence beyond France, fostering international collaboration in cancer research. Professor Heymann has been a prominent figure in multiple research projects, having managed and contributed to groundbreaking studies. His expertise in cancer biology, combined with his academic roles, has allowed him to mentor students and researchers, shaping the next generation of scientists. His dual role in academia and clinical practice makes him a leading figure in both spheres.

Awards and Honors:

Professor Dominique Heymann’s career is adorned with numerous accolades and honors. As a tenured professor at the University of Nantes, he has received recognition for his contributions to histology, embryology, and oncology. He was appointed as an Honorary Professor in Bone Oncology at the University of Sheffield, UK, an esteemed acknowledgment of his expertise in the field. His work in cancer research, particularly related to bone tumors, has earned him international recognition, and his published studies continue to be highly regarded in scientific journals. Additionally, Professor Heymann has contributed significantly to the understanding of osteosarcoma and bone regeneration, which has earned him awards from academic and clinical societies. His continuous impact in advancing the field through groundbreaking research, leadership in clinical oncology, and educational contributions has made him a highly respected figure in the medical and scientific communities.

Research Focus:

Professor Dominique Heymann’s research is focused on cancer, particularly bone tumors such as osteosarcoma, and the molecular mechanisms involved in bone regeneration. His work primarily investigates the signaling pathways that control bone remodeling, the interactions between tumor cells and the microenvironment, and the role of immune responses in bone diseases. One of his key research interests is the development of targeted therapies to combat cancer progression, with a special emphasis on novel anticancer agents, including glycosaminoglycan-mimetic compounds derived from marine bacterial exopolysaccharides. In addition, Professor Heymann is dedicated to studying the role of circulating tumor cells as predictive markers for drug resistance and tumor progression. His expertise also includes stem cell therapies, autophagy in osteoblasts, and the potential for therapeutic applications in bone repair and regeneration. His research aims to improve patient outcomes through innovative approaches in cancer treatment and bone health.

Publications Top Notes:

  • Heymann D, Muñoz-Garcia J, Babuty A, et al. A new promising anticancer agent: a glycosaminoglycan-mimetic derived from the marine bacterial infernan exopolysaccharide. Int J Biol Macromol. (in press) 🧬

  • Jacquot P, Muñoz-Garcia J, Léger A, et al. A multispecific checkpoint inhibitor Nanofitin with a fast tumor accumulation property and antitumor activity in immune competent mice. Biomolecules. (in press) 🔬

  • Yadav P, Heymann D, Prasad RN. Circulating tumor cells: a predictive marker for drug resistance and tumor progression. Front Oncol. (in press) 🔬

  • Muñoz-Garcia J, et al. Interleukin-34 orchestrates bone formation through its binding to Bone Morphogenic Proteins. Theranostics. 2025; 15(7):3185-3202. 🦴

  • Young RJ, et al. CIRCUS: CIRCUlating tumor cells in soft tissue Sarcoma – a short report. Cancer Drug Resist. 2022; 4:51. 💉

  • Oliver L, et al. Transcriptional landscape of the interaction of human mesenchymal stem cells with glioblastoma in bioprinted co-cultures. Stem Cell Res Ther. 2024; 15(1):424. 🧫

  • Cordova LA, et al. Why are osteoporosis patients treated with antiresorptive therapies considered like oncology patients regarding their oral health care? Osteoporos Int. 2024; 35(9):1677-1678. 🦷

  • Childs A, et al. A prospective observational cohort study for newly diagnosed patients in the UK: ICONIC study initial results. Cancers (Basel). 2024; 16(13):2351. 📊

  • Rey V, et al. A personalized medicine approach identifies enasidenib as an efficient treatment for IDH2 mutant chondrosarcoma. EBioMedicine. 2024; 102:105090. 🧬

  • Jubelin C, et al. Identification of MCM4 and PKRDC as new regulators of osteosarcoma cell dormancy based on 3D cultures. BBA Mol Cell Res. 2024; 1871:119660. 🧪

Conclusion:

Professor Dominique Heymann’s expertise in oncology, histology, and embryology positions him as an outstanding candidate for the Research for Best Researcher Award. His achievements in cancer research, particularly in bone tumors, and his contributions to advancing the understanding of tumor biology make him an exemplary figure. While there are areas to expand in terms of interdisciplinary collaborations and technological integration, his exceptional body of work and his dedication to both academic excellence and clinical practice make him a deserving candidate for this prestigious award.

Doaa Esmaeil | Cancer treatment | Best Researcher Award

Published on by Cell Biologist

Assoc. Prof. Dr. Doaa Esmaeil | Cancer treatment | Best Researcher Award

Assoc. Prof. Dr. Doaa Esmaeil , Mansoura university , Egypt

Dr. Doaa Abd Elmoneim Mohamed Esmaeil is an Associate Professor of Oral Pathology at Mansoura University, Egypt. She is a dedicated researcher focused on oral diseases, particularly in understanding their pathogenesis, molecular biology, and carcinogenesis. With a strong background in oral pathology, she has contributed to numerous studies and publications that explore various aspects of oral health, including cancer research and therapeutic strategies. Dr. Esmaeil’s research includes innovative work on the effects of different agents and treatments in combating oral diseases. Her extensive academic contributions have established her as a prominent figure in the field of oral pathology, both in Egypt and internationally. She is committed to advancing the understanding of oral diseases, particularly those linked to cancer, and plays an active role in advancing the knowledge of oral health practices.

Publication Profile:

Orcid

Strengths for the Award:

  1. Academic Excellence: Dr. Doaa Esmaeil is an Associate Professor in the Oral Pathology Department at Mansoura University, Egypt, with a strong academic background and expertise in oral diseases, particularly oral carcinogenesis and molecular biology. Her contributions to the scientific community through both teaching and research have made her a significant figure in the field.

  2. Research Contributions: Dr. Esmaeil has made notable contributions to oral pathology through her innovative research on molecular mechanisms in oral diseases, focusing on cancer pathogenesis, therapeutic agents, and disease prevention. Her research projects, such as exploring the efficacy of phytomedicines against chemotherapy-induced toxicity, demonstrate her commitment to improving therapeutic outcomes.

  3. International Recognition: She has published several papers in high-impact journals such as the European Journal of Dentistry, Saudi Dental Journal, and the Egyptian Dental Journal, showcasing her widespread impact in the field of oral pathology.

  4. Ongoing Contributions to the Field: Dr. Esmaeil’s research is forward-thinking, addressing cutting-edge topics like stem cells in oral cancer therapy, the role of molecular markers in oral diseases, and enhancing chemotherapeutic efficacy against head and neck cancers.

Areas for Improvement:

  1. Citation Impact: While Dr. Esmaeil has been an active researcher with publications in reputed journals, her citation index of 3, while a good start, could benefit from increased visibility and collaborations with larger research networks to elevate her work’s recognition and citation in the broader academic community.

  2. Industry Collaborations: Although Dr. Esmaeil’s academic and research work is notable, there appears to be limited documented collaboration with industry projects or patents. Strengthening connections with industry could help translate her research into practical applications, potentially enhancing the impact of her work.

  3. Multidisciplinary Collaboration: While Dr. Esmaeil has collaborated with researchers within the field of oral pathology, expanding these collaborations into multidisciplinary domains could provide a more comprehensive approach to her research and open new avenues for funding and innovation.

Education:

Dr. Doaa Abd Elmoneim Mohamed Esmaeil earned her Bachelor’s degree in Dental Medicine from Mansoura University, Egypt. She then pursued her Master’s and Ph.D. degrees in Oral Pathology, also from Mansoura University, where she developed a keen interest in the molecular mechanisms of oral diseases. Her academic journey has been enriched by her work on various research projects exploring oral carcinogenesis, molecular biology, and the development of therapeutic strategies for oral cancers. Dr. Esmaeil’s dedication to research and her extensive educational background have established her as an expert in oral pathology. She has participated in numerous international and national conferences, strengthening her expertise in both academic and clinical settings. Her education and commitment to continuous learning have shaped her approach to understanding and treating oral diseases, and she remains an influential educator and researcher at Mansoura University.

Experience:

Dr. Doaa Abd Elmoneim Mohamed Esmaeil has over a decade of experience in teaching and researching in the field of oral pathology. As an Associate Professor in the Oral Pathology Department at Mansoura University, she has played a pivotal role in educating undergraduate and postgraduate students in both theoretical and practical aspects of oral pathology. Her experience extends to leading numerous research projects in oral diseases, with a special focus on oral cancer, its molecular mechanisms, and therapeutic approaches. Dr. Esmaeil’s work on tissue biomarkers, cancer stem cells, and chemotherapeutic agents has been recognized internationally. Additionally, her role as a reviewer for several scientific journals has solidified her standing as a respected authority in oral pathology. Her collaborative projects with other universities and institutions, both local and international, have further enhanced her research expertise. Dr. Esmaeil’s passion for education and research continues to shape the future of oral pathology.

Research Focus:

Dr. Doaa Abd Elmoneim Mohamed Esmaeil’s research primarily focuses on the molecular pathogenesis of oral diseases, with a particular emphasis on oral cancer. Her work explores the complex mechanisms underlying carcinogenesis in the oral cavity, particularly focusing on the molecular markers, cell lines, and signaling pathways involved in cancer progression. Dr. Esmaeil is also interested in developing innovative therapeutic strategies for oral diseases, with research exploring the efficacy of various agents, including phytomedicines and synthetic compounds, against oral cancer and other related disorders. Her ongoing research examines the effectiveness of combining traditional treatments with new molecular-targeted therapies to improve patient outcomes. Additionally, she has investigated the role of cancer stem cells in therapy resistance and the development of new treatment modalities. Dr. Esmaeil’s research contributes to the broader understanding of oral diseases, aiming to improve both prevention and treatment options for conditions like oral squamous cell carcinoma.

Publication Top Notes:

  • The Impact of Silver Diamine Fluoride and Potassium Iodide Treatment on Microtensile Bonds Strength of Composite Restoration for Carious Dentin in Primary and Permanent Teeth and Its Potential Color Changes: An in Vitro Study 📄🦷

  • Antitumoral properties of the pomegranate peel and blueberry extracts against tongue carcinoma (in vitro study) 🍊🍇🦷

  • Oral squamous cell carcinoma Immunohistochemical Expression of PD L1 in Oral Epithelial Dysplasia 🦷🔬

  • Stem Cell Marker as A Factor for The Different Biological Behavior of Ameloblastoma and Odontogenic Keratocyst 🧬🦷

  • Diagnostic Value of Nuclear Receptor Subfamily 4 Group A Member 3 in Salivary Gland Carcinomas 🔬🦷

  • The controversial role of MDM2, MCM3 and Bcl-X in Ameloblastoma and Ameloblastic Carcinoma: An update 🧬🦷

  • Pomegranate molasses and red grape vinegar: can they alleviate dysplastic changes in chemically induced oral squamous cell carcinoma in hamsters? 🍑🍇🦷

  • Tumor stroma ratio as a parameter for prognosis and clinicopathological behavior of oral squamous cell carcinoma: A retrospective cohort study 📊🦷

  • Emerging therapeutic modality enhancing the efficiency of chemotherapeutic agents against head and neck squamous cell carcinoma cell lines 💊🦷

  • Angiogenesis and mast cells as predictive factors in behavior of Odontogenic cysts 🌱🦷

Conclusion:

Dr. Doaa Abd Elmoneim Mohamed Esmaeil is highly deserving of the Best Researcher Award. Her academic excellence, profound contributions to oral pathology, and commitment to advancing the understanding of oral diseases and cancer pathogenesis make her a strong candidate. By focusing on broadening her citation impact and enhancing her industry collaborations, Dr. Esmaeil has the potential to elevate her career to even greater heights. Her continued research and dedication to the scientific community position her as an influential researcher in the field of oral pathology, contributing not only to academia but also to real-world applications in oral healthcare.