Dominique Heymann | Cancer Cell Biology | Best Researcher Award

Prof. Dr. Dominique Heymann | Cancer Cell Biology | Best Researcher Award

Prof. Dr. Dominique Heymann , Nantes Université, CNRS, Institut de Cancérologie de l”Ouest , France

Professor Dominique Heymann is a highly esteemed academic and clinician, specializing in histology, embryology, and oncology. He is a Professor at Nantes University, France, and a Hospital Practitioner at the ICO Cancer Centre. With a wealth of experience in bone oncology and cancer research, he is also an Honorary Professor at the University of Sheffield, UK. His expertise spans from cell biology to immunology and biochemistry, and he is dedicated to advancing cancer research, particularly in the field of bone tumors and osteosarcoma. With numerous publications to his name and contributions to the global scientific community, Professor Heymann is recognized for his groundbreaking work in cell signaling and tumor progression. He is a valued researcher in the oncology community, with a strong focus on developing innovative therapies for cancer treatment.

Publication Profile:

Google Scholar

Strengths for the Award:

Professor Dominique Heymann is a distinguished figure in the field of oncology, particularly bone oncology, with a strong focus on the molecular mechanisms of bone tumors like osteosarcoma. His academic and clinical roles at the University of Nantes and the ICO Cancer Centre underscore his leadership in research and patient care. He has contributed significantly to understanding tumor biology, bone remodeling, and regenerative medicine, making him a highly respected expert in these fields. His research addresses crucial topics such as circulating tumor cells, targeted therapies, and the development of new anticancer agents, all of which are of immense value to advancing cancer treatment. With multiple publications in prestigious journals, including studies on novel therapies and molecular pathways in cancer progression, Professor Heymann has demonstrated exceptional scientific rigor. His global collaborations and recognition further establish him as a leading researcher in cancer biology and oncology.

Areas for Improvements:

Despite his numerous contributions, there are a few areas where Professor Heymann’s research could evolve. While he has made notable strides in cancer treatment and bone oncology, expanding research into more personalized medicine approaches and exploring the integration of AI and machine learning in predictive oncology could enhance the applicability of his findings. Furthermore, increasing collaborative efforts with international interdisciplinary teams could yield broader insights, especially in rare cancers and metastasis research. Developing a more extensive outreach to clinical trials and collaborations in broader regions may also allow for faster translation of his research into practice.

Education:

Professor Heymann began his academic journey at Paris VII University, where he earned a Master’s degree in Cell Biology in 1991. His PhD in Cell Biology and Immunology was completed at Nantes University in 1995, a pivotal moment in his career. Further expanding his knowledge, he pursued research management abilities and a deeper focus on Biochemistry and Cell Biology at Nantes University in 1998. He also received specialized certification in Histology from Nantes University in 1999 and later completed the required authorizations for animal experimentation in 2003 and 2016. Throughout his academic career, Professor Heymann has continually updated his qualifications, ensuring his expertise remains at the cutting edge of medical and biological sciences. His academic foundation has underpinned his significant contributions to cancer research, with a strong emphasis on bone oncology and regenerative medicine.

Experience:

Professor Dominique Heymann has an extensive and diverse career spanning several decades in both academic and clinical settings. Currently, he serves as a Professor of Histology/Embryology at Nantes University and as a Hospital Practitioner at the ICO Cancer Centre, where he is instrumental in patient care and research. His professional trajectory includes significant roles in oncology, particularly focused on bone tumors, osteosarcoma, and regenerative medicine. As an Honorary Professor at the University of Sheffield, he extends his influence beyond France, fostering international collaboration in cancer research. Professor Heymann has been a prominent figure in multiple research projects, having managed and contributed to groundbreaking studies. His expertise in cancer biology, combined with his academic roles, has allowed him to mentor students and researchers, shaping the next generation of scientists. His dual role in academia and clinical practice makes him a leading figure in both spheres.

Awards and Honors:

Professor Dominique Heymann’s career is adorned with numerous accolades and honors. As a tenured professor at the University of Nantes, he has received recognition for his contributions to histology, embryology, and oncology. He was appointed as an Honorary Professor in Bone Oncology at the University of Sheffield, UK, an esteemed acknowledgment of his expertise in the field. His work in cancer research, particularly related to bone tumors, has earned him international recognition, and his published studies continue to be highly regarded in scientific journals. Additionally, Professor Heymann has contributed significantly to the understanding of osteosarcoma and bone regeneration, which has earned him awards from academic and clinical societies. His continuous impact in advancing the field through groundbreaking research, leadership in clinical oncology, and educational contributions has made him a highly respected figure in the medical and scientific communities.

Research Focus:

Professor Dominique Heymann’s research is focused on cancer, particularly bone tumors such as osteosarcoma, and the molecular mechanisms involved in bone regeneration. His work primarily investigates the signaling pathways that control bone remodeling, the interactions between tumor cells and the microenvironment, and the role of immune responses in bone diseases. One of his key research interests is the development of targeted therapies to combat cancer progression, with a special emphasis on novel anticancer agents, including glycosaminoglycan-mimetic compounds derived from marine bacterial exopolysaccharides. In addition, Professor Heymann is dedicated to studying the role of circulating tumor cells as predictive markers for drug resistance and tumor progression. His expertise also includes stem cell therapies, autophagy in osteoblasts, and the potential for therapeutic applications in bone repair and regeneration. His research aims to improve patient outcomes through innovative approaches in cancer treatment and bone health.

Publications Top Notes:

  • Heymann D, Muñoz-Garcia J, Babuty A, et al. A new promising anticancer agent: a glycosaminoglycan-mimetic derived from the marine bacterial infernan exopolysaccharide. Int J Biol Macromol. (in press) 🧬

  • Jacquot P, Muñoz-Garcia J, Léger A, et al. A multispecific checkpoint inhibitor Nanofitin with a fast tumor accumulation property and antitumor activity in immune competent mice. Biomolecules. (in press) 🔬

  • Yadav P, Heymann D, Prasad RN. Circulating tumor cells: a predictive marker for drug resistance and tumor progression. Front Oncol. (in press) 🔬

  • Muñoz-Garcia J, et al. Interleukin-34 orchestrates bone formation through its binding to Bone Morphogenic Proteins. Theranostics. 2025; 15(7):3185-3202. 🦴

  • Young RJ, et al. CIRCUS: CIRCUlating tumor cells in soft tissue Sarcoma – a short report. Cancer Drug Resist. 2022; 4:51. 💉

  • Oliver L, et al. Transcriptional landscape of the interaction of human mesenchymal stem cells with glioblastoma in bioprinted co-cultures. Stem Cell Res Ther. 2024; 15(1):424. 🧫

  • Cordova LA, et al. Why are osteoporosis patients treated with antiresorptive therapies considered like oncology patients regarding their oral health care? Osteoporos Int. 2024; 35(9):1677-1678. 🦷

  • Childs A, et al. A prospective observational cohort study for newly diagnosed patients in the UK: ICONIC study initial results. Cancers (Basel). 2024; 16(13):2351. 📊

  • Rey V, et al. A personalized medicine approach identifies enasidenib as an efficient treatment for IDH2 mutant chondrosarcoma. EBioMedicine. 2024; 102:105090. 🧬

  • Jubelin C, et al. Identification of MCM4 and PKRDC as new regulators of osteosarcoma cell dormancy based on 3D cultures. BBA Mol Cell Res. 2024; 1871:119660. 🧪

Conclusion:

Professor Dominique Heymann’s expertise in oncology, histology, and embryology positions him as an outstanding candidate for the Research for Best Researcher Award. His achievements in cancer research, particularly in bone tumors, and his contributions to advancing the understanding of tumor biology make him an exemplary figure. While there are areas to expand in terms of interdisciplinary collaborations and technological integration, his exceptional body of work and his dedication to both academic excellence and clinical practice make him a deserving candidate for this prestigious award.

Weikuan Gu | Cancer Cell Biology | Best Researcher Award

Prof. Weikuan Gu | Cancer Cell Biology | Best Researcher Award

Prof. Weikuan Gu , UTHSC , United States

Weikuan Gu is a Professor at the University of Tennessee Health Science Center, specializing in biomedical research with a focus on disease modeling, genetic factors influencing health, and drug efficacy. After earning his MS and Ph.D. from Cornell University, he worked on eye diseases, osteoporosis, and genetics before joining UTHSC in 2002. His contributions in AI applications for biomedical research are noteworthy. He has developed the Principal Law of Lifespan (PLOSP) theory and has been recognized for his leadership in various international collaborative projects. With a significant role in numerous NIH-funded studies, his research continues to push boundaries in understanding disease mechanisms and therapeutics.

Publication Profile: 

Google Scholar

Strengths for the Award:

  1. Extensive Research Experience: Professor Weikuan Gu has over two decades of experience in biomedical research, demonstrating expertise across a wide array of disease models, drug efficacy, and genetic factors influencing health. His work spans a variety of high-impact fields such as ophthalmology, osteoporosis, arthritis, and genomics, showcasing a strong commitment to advancing understanding in multiple medical domains.

  2. Innovative Research Leadership: Professor Gu has been instrumental in leading and contributing to groundbreaking research, including his development of the Principal Law of Lifespan (PLOSP). His ability to innovate, especially in applying AI to biomedical research, positions him at the forefront of cutting-edge science and technology.

  3. Funded Projects & International Collaborations: He has secured substantial funding for his projects, totaling millions of dollars, and has led many high-profile international collaborations. This speaks to the global relevance and potential impact of his work, as well as his ability to manage large-scale research initiatives.

  4. Research Output and Citations: With 175 published scientific papers and multiple accepted articles in prestigious journals such as Cancer Letters and Ecotoxicology and Environmental Safety, his research continues to have a significant impact on the scientific community. His most recent work on AI applications and its implications for public health and disease diagnosis are particularly notable.

  5. Contribution to Education and Training: Professor Gu has played a key role in training future researchers, as evident from his leadership in the Gene Discovery Microarray Core at UTHSC and his involvement in several research education collaborations internationally. His contributions to scientific training are essential for developing the next generation of researchers.

Areas for Improvement:

  1. Broader Public Outreach: While Professor Gu’s research has made significant contributions to the scientific community, there is room to enhance the visibility of his work among broader audiences, including policy makers, healthcare professionals, and the general public. Public engagement with his AI-focused research could improve the real-world application of his findings, especially in public health.

  2. Interdisciplinary Collaboration: Although his collaborations are already diverse, fostering even more interdisciplinary collaborations with experts from areas like data science, engineering, and social sciences could expand the scope of his research, especially in areas like AI and healthcare.

Education:

Dr. Gu completed his MS and Ph.D. from Cornell University, where he specialized in molecular genetics. His academic journey focused on genetic disorders, particularly in disease modeling and understanding complex genetic mechanisms. His research provided foundational insights into eye diseases and osteoporosis, leading to his early work at Loma Linda University and later at the University of Tennessee Health Science Center. His vast academic knowledge enables him to merge genetic research with cutting-edge technologies, including AI applications in biomedical research, paving the way for transformative healthcare solutions.

Experience:

Dr. Weikuan Gu has a rich career that spans over two decades in biomedical research. His early work at Loma Linda University involved osteoporosis and genetic studies in human and mouse models. Since joining the University of Tennessee Health Science Center in 2002, his research expanded to disease modeling, drug efficacy, and the role of genetics in health. He has been a principal investigator and co-investigator in numerous NIH-funded projects, specializing in genetic factors influencing diseases like osteoarthritis, fibrotic diseases, and stroke. Additionally, he is involved in AI-based research, advancing the integration of AI in biomedical research methodologies.

Research Focus:

Dr. Weikuan Gu’s research is centered on understanding disease mechanisms and therapeutic strategies, with a focus on genetic and molecular factors. His work spans glaucoma therapy, fibrotic diseases, and AI in biomedical research. He is the lead on various NIH-funded projects, investigating genetic regulation in conditions like osteoarthritis and stroke. One of his innovative contributions is the Principal Law of Lifespan (PLOSP), a theory aimed at understanding the aging process. His multidisciplinary approach, combining traditional genetic research with modern technologies such as AI, positions him at the forefront of cutting-edge biomedical research.

Publications Top Notes:

  1. “Generating Research Hypotheses to Overcome Key Challenges in the Early Diagnosis of Colorectal Cancer – Future Application of AI” 🧬
  2. “Alarm: Retracted Articles on Cancer Imaging Are Not Only Continuously Cited by Publications but Also Used by ChatGPT to Answer Questions” 💻
  3. “Evaluation of the Potential Value of Artificial Intelligence (AI) in Public Health Using Fluoride Intake as the Example” 🤖

Conclusion:

Professor Weikuan Gu is an exceptionally qualified candidate for the Best Researcher Award. His extensive experience, leadership in innovative research, impressive body of published work, and commitment to advancing both scientific discovery and education make him a standout candidate. While there are opportunities for further enhancing public outreach and expanding interdisciplinary collaborations, his ongoing contributions to AI in biomedicine and genetic research firmly establish him as a leader in his field.

Chang Feng | Cancer Cell Biology | Best Researcher Award

Dr. Chang Feng | Cancer Cell Biology | Best Researcher Award

Dr. Chang Feng , Shanghai University , China

Chang Feng is a distinguished researcher in the fields of tumor molecular diagnosis, biosensing, and intelligent DNA. Born in Shanghai, China, on January 1, 1988, Chang Feng pursued a rigorous academic journey, completing his Ph.D. at Nanjing University (2015-2019) after earning his M.D. from Shanghai University (2012-2015). He is currently a lecturer at Shanghai University since 2019. Feng has contributed significantly to scientific advancements in cancer diagnostics, molecular biosensors, and cutting-edge DNA research. His works often involve the development of innovative detection techniques and the creation of novel DNA-based diagnostic systems. Feng has a collaborative approach, working with multiple researchers to achieve groundbreaking results. His publications in prestigious journals highlight his expertise in developing biosensors, RNA origami, and catalytic DNAzymes for biomedical applications.

Publication Profile: 

Scopus

Strengths for the Award:

Chang Feng’s research is exceptional and well-suited for the Best Researcher Award. His expertise spans across tumor molecular diagnosis, biosensor development, and intelligent DNA systems. His contributions to cancer diagnostics, bioimaging, and biosensing technologies are groundbreaking. Feng has published several high-impact articles in leading journals, demonstrating significant advancements in DNAzymes, electrochemical biosensing, and RNA origami. His work in designing innovative DNA-based diagnostic platforms and cancer therapies reflects his ability to integrate chemistry, biology, and engineering, providing novel solutions for clinical applications. Feng’s interdisciplinary approach and leadership in the field have earned him numerous collaborations with researchers and institutions globally, further enhancing his credibility as a top-tier researcher.

Areas for Improvements:

While Feng has made remarkable contributions to scientific research, one area for improvement is expanding his focus to more clinical applications of his findings. Commercializing his biosensing technologies for real-world healthcare implementation would increase the practical impact of his work. Additionally, improving outreach through public science communication could help raise awareness of his advancements and engage a broader audience.

Education:

Chang Feng received his M.D. from Shanghai University in 2015, where he developed a strong foundation in molecular biology, diagnostics, and bioengineering. His doctoral journey continued at Nanjing University (2015-2019), where he obtained his Ph.D. focusing on tumor molecular diagnosis and biosensing technologies. During his time at Nanjing University, Feng’s research concentrated on the development of DNA-based biosensors and new methodologies for cancer detection. His education at these esteemed institutions provided him with the technical expertise necessary to pioneer groundbreaking research in the field of molecular diagnostics. Feng’s academic training involved rigorous coursework in molecular biology, chemical engineering, and bioinformatics, contributing significantly to his current work in bioimaging, biosensing, and the development of intelligent DNA systems.

Experience:

Chang Feng has a strong academic and research career, currently serving as a lecturer at Shanghai University since 2019. Prior to his current role, he earned his Ph.D. at Nanjing University (2015-2019) and M.D. from Shanghai University (2012-2015). Throughout his career, Feng has collaborated with leading researchers, contributing to the development of innovative biosensing technologies and cancer diagnostics. His work includes advancing DNA-based biosensors, DNAzyme probes, and other cutting-edge diagnostic tools. As a lecturer, Feng mentors graduate students and participates in academic teaching and research projects. He has been involved in several collaborative publications that have furthered the field of molecular biosensors, focusing on intelligent DNA-based systems and tumor detection methodologies. Feng’s research experience combines theoretical knowledge with practical applications, making him a recognized figure in the field of biosensor research and molecular diagnostics.

Research Focus:

Chang Feng’s primary research focus lies in tumor molecular diagnosis, biosensor development, and intelligent DNA systems. He is particularly interested in advancing technologies for cancer detection through the application of molecular biosensors, bioimaging, and intelligent DNA devices. His research explores the use of DNAzymes, catalytic DNA molecules, and RNA origami for targeted molecular detection, with a focus on enhancing the sensitivity and specificity of cancer diagnostics. Feng’s work also investigates the use of biosensors for the detection of small molecules, leveraging innovative electrochemical and fluorescence-based platforms. His interdisciplinary approach combines elements of chemistry, biology, and engineering to create advanced diagnostic systems with potential clinical applications. Feng is dedicated to improving the efficiency of diagnostic tools and is committed to developing more accurate and faster methods for early cancer detection and molecular analysis.

Publications Top Notes:

  1. Single-cell analysis of highly metastatic circulating tumor cells by combining a self-folding induced release reaction with a cell capture microchip 🧬🔬 (Anal. Chem., 2021)
  2. Hierarchical biomarkers detection via a universal polydopamine probe catalyzed by a hexagonal star-nanostructured DNAzyme 🔬🧪 (Sensor. Actuat. B-Chem., 2022)
  3. Construction of a ternary complex based DNA logic nanomachine for a highly accurate imaging analysis of cancer cells 🧬💡 (ACS Sens., 2020)
  4. Lantern-shaped flexible RNA origami for Smad4 mRNA delivery and growth suppression of colorectal cancer 🧬🦠 (Nat. Commun., 2023)
  5. Liquid-colloid-solid modular assembly for three-dimensional electrochemical biosensing of small molecules 💧⚡ (Biosens. Bioelectron., 2024)
  6. Dual-targets binding protection mediated rolling circle transcription with tandem fluorescent RNA aptamers for label-free detection of liver cancer biomarkers 🧬🦠 (Sensor. Actuat. B-Chem., 2024)
  7. Cell-Free Biosensing Genetic Circuit Coupled with Ribozyme Cleavage Reaction for Rapid and Sensitive Detection of Small Molecules 🧬⚡ (ACS Synth. Biol., 2023)
  8. A portable and partitioned DNA hydrogel chip for multitarget detection 💧🧬 (Lab Chip., 2023)

Conclusion:

Chang Feng’s research in tumor molecular diagnostics, biosensors, and intelligent DNA is truly cutting-edge. His scientific rigor, collaboration with top researchers, and groundbreaking discoveries in cancer detection and biosensing technologies make him a deserving candidate for the Best Researcher Award. By continuing to bridge the gap between laboratory research and clinical applications, Feng will likely have an even greater impact in advancing medical diagnostics and therapeutic strategies.

Jacob Wekalao | Cancer Cell Biology | Best Researcher Award

Mr. Jacob Wekalao | Cancer Cell Biology | Best Researcher Award

Mr. Jacob Wekalao , USTC CHINA , China

Jacob Wekalao is a Physics professional and researcher with extensive experience in both academia and industry. He holds a Doctor of Philosophy from the University of Science and Technology and a Master of Science in Physics from Marwadi University, India. Jacob has worked as a physics teacher, leading the physics department at Kwale High School, Kenya, and is currently a software expert at Eujim Solutions, where he specializes in creating innovative business solutions. He is also a Research Assistant at Marwadi University, contributing to advanced research in physics and nanotechnology. His expertise spans across terahertz sensors, graphene-based biosensors, and surface plasmon resonance techniques. In addition to his academic endeavors, Jacob has authored several peer-reviewed publications, showcasing his contributions to forensic science, health, and biomedical applications. Jacob is passionate about research, mentoring, and leveraging technology to solve real-world problems.

Publication Profile:

Orcid

Strengths for the Award:

Jacob Wekalao is an exceptional researcher in the field of experimental physics, particularly in the areas of nanotechnology, terahertz sensors, and biosensing. His work integrates cutting-edge research with practical applications, demonstrating a high level of innovation and expertise. Jacob’s contributions to the development of graphene-based sensors for various applications, including healthcare, forensic science, and security, have positioned him as a thought leader in his field. His published works in prestigious journals and his active role in research projects, such as designing biosensors for early disease detection, highlight his proficiency in both theoretical and applied physics. Additionally, Jacob’s ability to collaborate internationally and present at major conferences reflects his commitment to advancing scientific knowledge and networking within the global research community.

Areas for Improvement:

While Jacob excels in his research and technological expertise, expanding his focus on interdisciplinary collaborations could further elevate his work. Engaging more with industry experts in areas like artificial intelligence or machine learning could also open doors for more transformative innovations, especially in optimizing sensor technologies. Further involvement in policy or public science initiatives could help bridge the gap between research and broader societal applications.

Education:

Jacob Wekalao has an impressive educational background that supports his expertise in physics and technology. He is currently pursuing a Doctor of Philosophy at the University of Science and Technology, China. His academic journey began with a Bachelor of Education in Science with a focus on Physics and Mathematics from the University of Embu, Kenya (2016-2020). This solid foundation propelled him to obtain a Master of Science in Physics from Marwadi University, Rajkot, Gujarat, India (2021-2023). During his time at Marwadi University, Jacob excelled academically, earning an Academic Gold Medal in November 2023 for his outstanding performance. His commitment to learning is also reflected in certifications from institutions like KAIST and the Israel Institute of Technology. Jacob’s education is characterized by a blend of theoretical knowledge and practical skills, which has enabled him to contribute significantly to the fields of experimental physics and applied technology.

Experience:

Jacob Wekalao has diverse experience spanning education, research, and industry. From September 2019 to August 2021, he worked as a Physics teacher at Kwale High School, Kenya, where he led the physics department, developed curriculum materials, and managed science projects. This role enabled him to foster critical thinking and scientific inquiry among students. In addition to his teaching experience, Jacob is currently employed as a Software Expert at Eujim Solutions, Kenya (July 2023 – Present), where he provides tailored software solutions, improves business efficiency, and implements cutting-edge technologies. Furthermore, he works as a Research Assistant at Marwadi University, collaborating on various physics research projects focused on terahertz sensors and biosensors. His involvement in multiple projects and publications has established him as a valuable contributor to advancements in technology and scientific research. Jacob’s work showcases a seamless integration of theoretical physics and practical application in technology.

Awards and Honors:

Jacob Wekalao’s dedication to academic excellence and research has earned him notable awards and honors. He received the prestigious Academic Gold Medal from Marwadi University, Rajkot, India, in November 2023, recognizing his exceptional performance in the Master of Science in Physics program. Jacob’s achievements are further validated by his numerous peer-reviewed publications, which have contributed to the global scientific community. His research in the fields of biosensing, terahertz technology, and nanomaterials has earned him recognition at various international platforms. In addition to academic awards, Jacob’s work has been presented at leading conferences, such as the International Conference on Chemical Safety and Security for Health and Environment (ICCSSHE), held in India in December 2023. His strong academic performance, leadership in research, and contributions to technological advancements continue to set him apart as an outstanding professional in his field.

Research Focus:

Jacob Wekalao’s research focuses on experimental physics, particularly in the areas of terahertz technology, biosensing, and nanomaterials. His work has significant implications for applications in healthcare, security, and forensic science. Jacob has developed and optimized graphene-based terahertz surface plasmon resonance sensors for the detection of various biomolecules, including hemoglobin and illicit drugs. His research has extended to the design of graphene metasurfaces for efficient detection of diseases like malaria and COVID-19. Jacob’s research in biosensors has led to highly sensitive, cost-effective solutions that hold promise for point-of-care diagnostics and environmental monitoring. Additionally, his work on the use of metasurfaces for explosive detection has practical implications for security. Through his research, Jacob combines advanced theoretical physics with real-world applications, contributing to the fields of biomedical technology, environmental monitoring, and security. His interest in machine learning also aids in optimizing these sensor technologies for better precision and performance.

Publications Top Notes:

  1. “Graphene-based THz surface plasmon resonance biosensor for hemoglobin detection applicable in forensic science.” 📖🔬
  2. “Design of ring and cross-shaped graphene metasurface sensor for efficient detection of malaria and 2-bit encoding applications.” 🦠🔍
  3. “Waterborne bacteria detecting highly sensitive graphene metasurface-based cost-efficient and efficient refractive index sensors.” 💧🔬
  4. “Design of graphene metasurface sensor for efficient detection of COVID-19.” 🦠💡
  5. “Graphene biosensor design based on glass substrate for forensic detection of illicit drugs.” 💊🔍
  6. “Graphene and Gold Metasurface-Based Terahertz Surface Plasmon Resonance Sensor for Explosive Detection.” 💥🛡️
  7. “Terahertz Optical Ultrasensitive Glucose Detection Using Graphene and Silver Surface Plasmon Resonance Metasurfaces for Biomedical Applications.” 🩺🔬
  8. “High-Sensitivity Graphene-Gold Metasurface Optical Biosensor for Early Melanoma Detection Optimized with Machine Learning Using a One-Dimensional Convolutional Neural Network and Binary Encoding.” 🧬🔬

Conclusion:

Jacob Wekalao’s contributions to the fields of physics and technology demonstrate an impressive combination of academic excellence, hands-on expertise, and innovative solutions. His drive to advance scientific knowledge and apply it for real-world impact, especially in healthcare and security, makes him a deserving candidate for the Best Researcher Award. Jacob’s ongoing work on high-sensitivity biosensors and his ability to stay ahead of technological trends make him a standout researcher in his field.

 

 

 

Iwona Kwiecień | Cancer Cell Biology | Best Researcher Award

Assist. Prof. Dr. Iwona Kwiecień | Cancer Cell Biology | Best Researcher Award

Assist. Prof. Dr. Iwona Kwiecień , Military Institute of Medicine – National Research Institute , Poland

Iwona Kwiecień, PhD, is an expert in clinical immunology and laboratory medicine. With a strong academic background and extensive experience in medical research, she has dedicated her career to exploring immunological mechanisms in various diseases. She is currently working at the Military Institute of Medicine in Warsaw, where she serves as a lab specialist and lecturer. Dr. Kwiecień holds a PhD in Medical Science with a specialization in immunology from the Medical University of Warsaw. Her research focuses on the immune response in lung cancer, sarcoidosis, and other inflammatory diseases, employing advanced techniques such as multicolor flow cytometry. Her scientific contributions have been recognized globally, and she continues to shape the field of immunology through her research and teaching.

Publication Profile:

Scopus

Strengths for the Award:

Dr. Iwona Kwiecień possesses an impressive academic background and a consistent record of significant contributions to the field of immunology and medical research. With a Ph.D. in Medical Science and immunology, along with expertise in laboratory medicine, hematology, and flow cytometry, Dr. Kwiecień has shown remarkable skill in investigating the immune system’s role in lung cancer and other diseases. Her work on antigenic profiles in the lung cancer microenvironment, macrophage subpopulations in lung cancer, and immune responses in systemic inflammation highlights her strong research abilities. The 2024 habilitation diploma is a testament to her research excellence. Furthermore, Dr. Kwiecień has contributed to the publication of numerous peer-reviewed articles with significant citations and impact, indicating her strong presence in the scientific community.

Areas for Improvement:

While Dr. Kwiecień has demonstrated significant strength in immunological research, expanding her focus to include other cancer types or diseases beyond lung cancer may broaden the scope of her impact. Additionally, fostering greater international collaboration could further enhance the dissemination of her research globally.

Education:

Iwona Kwiecień earned her Master of Science in Laboratory Medicine from the Medical University of Warsaw in 2012. Later, she completed her PhD at the same university’s First Faculty of Medicine, specializing in immunology, with a thesis on regulatory mechanisms of the immune response, which she defended in 2017. She further pursued a specialization in Laboratory Medical Hematology at the Medical University of Silesia in Katowice, Poland, completing it in 2021. Dr. Kwiecień is also set to receive her habilitation diploma from the Military Institute of Medicine-National Research Institute in 2024, based on her scientific achievements in lung cancer immunology. Throughout her academic journey, she has developed expertise in clinical cytology, flow cytometry, and immunological assays, contributing significantly to the scientific community.

Experience:

Dr. Iwona Kwiecień has accumulated substantial experience in the field of laboratory medicine and immunology, working at several prestigious institutions. Since 2017, she has been a laboratory specialist and lecturer at the Military Institute of Medicine-National Research Institute in Warsaw, focusing on flow cytometry and hematology. Her role involves designing, performing, and analyzing complex experiments, as well as providing education and training to students. Prior to her current position, Dr. Kwiecień worked as a research coordinator assistant at BioVirtus Research Site and Clinical Research Group in Warsaw. Her academic career also includes time spent at the University Clinical Center of the Medical University of Warsaw, where she collaborated on various pathology and immunology projects. Dr. Kwiecień’s professional experience extends to overseeing numerous grants and research projects, including her work on macrophage subpopulations and lung cancer.

Awards and Honors:

Dr. Iwona Kwiecień has received several accolades in recognition of her outstanding contributions to science and research. Among her awards is the prestigious “Gold Laurel Graduate” medal for being the best graduate of Laboratory Medicine at the Medical University of Warsaw in 2013. She also received the 2nd award from the Polish Archives of Internal Medicine for her student research on macrophage subpopulations in sarcoidosis in 2014. Additionally, Dr. Kwiecień has been the recipient of numerous research grants, including the 2014-2015 Grant for Young Scientific Researcher from the Medical University of Warsaw. Her work on macrophage subpopulations in lung cancer earned her a statutory grant at the Military Institute of Medicine in 2018-2019. These awards reflect her exceptional research contributions and commitment to advancing the field of clinical immunology and laboratory medicine.

Research Focus:

Dr. Iwona Kwiecień’s research focus lies primarily in the immunology of lung cancer, sarcoidosis, and inflammatory diseases. Her studies have explored immune responses, particularly the role of macrophages, regulatory T cells, and other immune cell populations in disease progression. A key area of her research involves the use of multicolor flow cytometry to assess antigenic profiles of cells in cancer microenvironments. She has contributed to the understanding of how immune cells, such as T cells and macrophages, interact with tumor cells in the context of lung cancer and other inflammatory conditions. Dr. Kwiecień has also researched the impact of systemic inflammation on diseases like obstructive sleep apnea. Her work aims to uncover novel therapeutic targets and provide insights into the immune mechanisms driving various pathologies. Through her research, Dr. Kwiecień continues to contribute valuable knowledge to the fields of clinical immunology and hematology.

Publications Top Notes:

  1. Frequency and spontaneous cytotoxicity of natural killer cells in healthy children: preliminary results 🧬🧒
  2. Association between M1 and M2 macrophages in bronchoalveolar lavage fluid and tobacco smoking in patients with sarcoidosis 💨🫁
  3. Cytometric analysis of perforin expression in NK cells, CD8+, and CD4+ lymphocytes in children with autoimmune Hashimoto’s thyroiditis 👶🦠
  4. T, B, and NKT Cells in Systemic Inflammation in Obstructive Sleep Apnea 😴🩺
  5. Macrophage polarization in interstitial lung diseases 💔🫁
  6. D4+/CD25high/FoxP3+/CD127- regulatory T cells in bronchoalveolar lavage fluid of lung cancer patients 🫀💉
  7. Elevated regulatory T cells, surface and intracellular CTLA‐4 expression and interleukin‐17 in the lung cancer microenvironment in humans 🫀🧪
  8. Elevated Foxp3/CD8 ratio in lung adenocarcinoma metastatic lymph nodes resected by transcervical extended mediastinal lymphadenectomy 🔬💊
  9. Immunophenotype of t cells expressing programmed death-1 and cytotoxic T cell antigen-4 in early lung cancer: local vs. systemic immune response 🎗️🫁
  10. Fas-positive lymphocytes are associated with systemic inflammation in obstructive sleep Apnea syndrome 🛏️🔬

Conclusion:

Dr. Iwona Kwiecień is a highly capable researcher whose work has made substantial contributions to clinical immunology. Her ongoing focus on the immune responses in cancer offers significant potential for advancing cancer diagnostics and therapeutics. With a strong academic and research background, she is undoubtedly a strong candidate for the Best Researcher Award.

 

 

 

 

 

Arunima Biswas | Cancer Cell Biology | Best Researcher Award

Assist. Prof. Dr. Arunima Biswas | Cancer Cell Biology | Best Researcher Award

Assist. Prof. Dr. Arunima Biswas , university of kalyani , India

Dr. Arunima Biswas is an Assistant Professor in the Department of Zoology at the University of Kalyani, India. With a Ph.D. in Biochemistry from the Indian Institute of Chemical Biology, Kolkata, she has focused her career on understanding the molecular mechanisms underlying diseases, particularly cancer and parasitic infections. She leads multiple funded research projects, aiming to develop targeted therapies for various cancers. Dr. Biswas has worked extensively on the cyclic nucleotide signaling pathways in unicellular eukaryotes like Leishmania and cancer. A passionate educator and researcher, she mentors Ph.D. students and collaborates with international scientists to advance medical research.

Publication Profile:

Scopus

Strengths for the Award:

Dr. Arunima Biswas demonstrates significant contributions to cancer research and parasitology. She is highly skilled in understanding and manipulating cyclic nucleotide signaling pathways, which play a crucial role in cancer biology and parasitic diseases like Leishmania infections. With several ongoing research projects, including the repurposing of phosphodiesterase inhibitors for cancer therapy and the development of targeted drug delivery systems, Dr. Biswas has shown an innovative approach to solving complex medical challenges. Her leadership as Principal Investigator for high-impact projects, such as cancer screening and drug targeting, highlights her as a leading researcher in her field. Furthermore, her dedication to mentoring and producing highly qualified Ph.D. students is commendable.

Areas for Improvement:

While Dr. Biswas’ research is already impactful, expanding her work on the practical clinical application of her findings could further bridge the gap between research and patient care. Collaboration with clinical trials or hospitals could expedite the translation of her findings into therapeutic solutions. Additionally, expanding interdisciplinary collaborations could bring novel insights into her research.

Education:

Dr. Arunima Biswas earned her Ph.D. in Biochemistry from the Indian Institute of Chemical Biology, Kolkata, with a thesis on Host-parasite interaction: Modulation of signaling pathways in Macrophage and Leishmania (2010). Prior to this, she completed her Master of Science in Zoology from the University of Calcutta with First Class honors (2005). She also holds a Bachelor of Science in Zoology from Maulana Azad College, University of Calcutta (2003). Her academic journey has been marked by a strong foundation in biochemistry, signaling pathways, and parasitology, forming the basis of her current research interests.

Experience:

Dr. Arunima Biswas has over a decade of teaching and research experience. As an Assistant Professor at the University of Kalyani, she has significantly contributed to the academic and research growth in the Department of Zoology. She is the Principal Investigator of several research projects funded by national bodies like CSIR, SERB, and UGC, with an emphasis on cancer research, especially targeting pathways involving cyclic nucleotides. Dr. Biswas has also collaborated with multiple national and international institutions and mentored several Ph.D. students, contributing to their academic and research advancements. Her experience in guiding research and mentoring future scientists is widely acknowledged.

Awards and Honors:

Dr. Arunima Biswas has received numerous accolades for her research and academic contributions. Notably, she won the Young Scientist Presentation Award at the Translational Cancer Research Conference (2020) and was honored with an International Congress of Cell Biology Travel Award (2016). She also received the American Society of Biochemistry and Cell Biology Travel Award (2015) and the prestigious DST-INSPIRE Faculty Scheme award (2012). These recognitions underscore her outstanding contributions to biomedical research, particularly in cancer biology and parasitology, further establishing her as a leader in her field.

Research Focus:

Dr. Arunima Biswas’s research focuses on cancer biology and parasitology, particularly the role of cyclic nucleotide signaling in cancer and Leishmania infections. She investigates therapeutic targets to modulate these pathways for better treatment options in cancer, including breast and gynecological cancers. Her ongoing projects include exploring phosphodiesterase inhibitors for breast cancer and cervical cancer, as well as developing vesicular drug carriers for targeted drug delivery. Dr. Biswas is dedicated to understanding the molecular intricacies of host-parasite interactions and their implications for disease management.

Publications Top Notes:

  1. Metal Oxide–Enhanced Para-Coumaric Acid Nanoparticles for Precision Targeting of Leishmania donovani
  2. Repurposing Approved Protein Kinase Inhibitors as Potent Anti-Leishmanials Targeting Leishmania MAP Kinases
  3. Anticancer, Antimicrobial, and Photocatalytic Activities of a New Pyrazole-Containing Thiosemicarbazone Ligand and Its Co(III) and Ni(II) Complexes
  4. Synthesis, Spectroscopy, and Structural Elucidation of Two New CoII and NiII Complexes of Pyrazole Derived Heterocyclic Schiff Base Ligand as Potential Anticancer and Photocatalytic Agents
  5. Vesicle-Encapsulated Rolipram (PDE4 Inhibitor) and Its Anticancer Activity
  6. Rhodamine Hydrazide-Linked Naphthalimide Derivative: Selective Naked Eye Detection of Cu2+, S2− and Understanding the Therapeutic Potential of the Copper Complex as an Anti-Cervical Cancer Agent
  7. Modulation and Determination of the Status of Inflammasomes in Leishmania-Infected Macrophages
  8. Catalytic and Anticancer Activity of Two New Ni(II) Complexes with a Pyrazole-Based Heterocyclic Schiff-Base Ligand
  9. Biophysical Study on DNA and BSA Binding Activity of Cu(II) Complex: Synthesis, Molecular Docking, Cytotoxic Activity, and Theoretical Approach
  10. Cytotoxic Behavior and DNA/BSA Binding Activity of Thiosemicarbazone-Based Ni(II) Complex: Bio-Physical, Molecular Docking, and DFT Study

Conclusion:

Dr. Arunima Biswas is an exceptional candidate for the “Best Researcher Award.” Her diverse research in cancer biology, parasitology, and drug development showcases her commitment to advancing healthcare. She has made significant strides in understanding complex molecular mechanisms, and her work holds great promise for improving cancer treatments. With a robust academic record, influential publications, and ongoing impactful projects, Dr. Biswas is undoubtedly a deserving contender for the award.

 

 

 

Annoor Awadasseid | Cancer Cell Biology | Best Researcher Award

Dr. Annoor Awadasseid | Cancer Cell Biology | Best Researcher Award

Dr. Annoor Awadasseid , Zhejiang University of Technology , Sudan

Dr. Annoor Awadasseid is a dedicated biochemist and molecular biologist specializing in medicinal chemistry, with a profound focus on cancer treatment. With a rich background in the exploration of novel small-molecule compounds, his research is at the forefront of developing potential therapeutic drugs for oncology. Dr. Awadasseid has made significant contributions to biochemistry, molecular biology, and cancer therapy, integrating his expertise to evaluate promising compounds. Passionate about enhancing patient outcomes, he collaborates extensively with interdisciplinary teams and mentors junior researchers. Currently, he is a Senior Researcher at Hangzhou Qingzhenghong Technology Co., Ltd., where he leads oncology-focused R&D initiatives, developing novel cancer therapies. He has authored numerous high-impact publications, showcasing his commitment to advancing therapeutic approaches for cancer care.

Publication Profile:

Google Scholar

Strengths for the Award:

Dr. Annoor Awadasseid exhibits outstanding qualities as a researcher in the field of biochemistry and molecular biology, particularly within cancer therapeutics. His expertise in evaluating small-molecule compounds for cancer treatment is evident through his advanced knowledge of biochemical processes, medicinal chemistry, and molecular biology techniques. Dr. Awadasseid has significantly contributed to the design and development of novel therapeutic agents, particularly targeting the PD-1/PD-L1 immune checkpoint pathway, which is critical for cancer immunotherapy. His ability to collaborate with interdisciplinary teams and mentor junior researchers demonstrates a strong leadership role in advancing scientific knowledge and fostering innovation. His extensive publication record in prestigious journals, alongside the recognition he has received via multiple scholarships and awards, further attests to the high impact of his research and contributions to improving patient care.

Areas for Improvement:

While Dr. Awadasseid’s research is impressive and impactful, further diversification of research methodologies could enhance his work. For instance, incorporating more cutting-edge computational techniques and expanding collaborations with clinical research teams could accelerate the translation of his lab-based discoveries into clinical applications. Additionally, increasing visibility in international scientific conferences would allow Dr. Awadasseid to expand his professional network, share insights, and potentially collaborate on global-scale projects. Engaging in multidisciplinary research that spans beyond oncology could also create new avenues for discovery and broaden his research impact.

Education:

Dr. Awadasseid’s academic journey includes a Ph.D. in Medicinal Chemistry from the University of Chinese Academy of Sciences (2017-2020), where he specialized in the design and evaluation of therapeutic compounds. Prior to that, he earned another Ph.D. in Biochemistry and Molecular Biology from Dalian Medical University (2014-2017). His earlier studies culminated in a Master’s degree in Biochemistry and Molecular Biology from Northeast Normal University (2012-2014). These rigorous educational experiences have honed his skills in biochemical and molecular techniques, which form the foundation for his groundbreaking research in cancer therapy. Dr. Awadasseid’s extensive training across multiple renowned institutions equipped him with the tools to explore novel therapeutic pathways, ultimately paving the way for his contributions to drug discovery and cancer treatment.

Experience:

Dr. Awadasseid has over a decade of experience in biochemistry, molecular biology, and medicinal chemistry. Following his postdoctoral fellowship at Zhejiang University of Technology (2020-2024), where he focused on small-molecule drug evaluation for cancer therapy, he became a Senior Researcher at Hangzhou Qingzhenghong Technology Co., Ltd. (2024-present). In this role, he leads R&D initiatives, specializing in the discovery and development of novel small-molecule compounds for oncology. His work includes evaluating drug efficacy through preclinical models, optimizing therapeutic candidates, and integrating interdisciplinary insights to drive advancements in targeted cancer therapies. Dr. Awadasseid’s expertise spans a variety of techniques, including CRISPR/Cas9 gene editing, flow cytometry, and qPCR, supporting his pivotal contributions to improving cancer treatment and patient outcomes. He also mentors junior researchers and contributes to intellectual property creation, including patents and publications in prestigious journals.

Awards and Honors:

Dr. Awadasseid has received prestigious accolades throughout his career. He was awarded the CAS-TWAS President’s Fellowship Programme (2017-2020) for his Ph.D. studies at the University of Chinese Academy of Sciences, recognizing his potential for significant scientific contributions. Additionally, he received the Liaoning Provincial Government Scholarship (2014-2017) while pursuing his Ph.D. at Dalian Medical University. The Chinese Government Scholarship (2012-2014) was awarded to him for his Master’s degree studies at Northeast Normal University, reflecting his academic excellence and commitment to advancing research in biochemistry and molecular biology. These scholarships and awards highlight Dr. Awadasseid’s dedication to his field, his research accomplishments, and his potential to make lasting impacts in the realm of cancer therapy and medicinal chemistry.

Research Focus:

Dr. Awadasseid’s research is centered on the development and evaluation of novel small-molecule compounds for cancer treatment, specifically focusing on their mechanisms and potential as therapeutic agents. His work aims to identify promising candidates that could enhance patient outcomes in oncology. He has a strong interest in the design and synthesis of therapeutic molecules, particularly those targeting the PD-1/PD-L1 pathway and other key molecules involved in cancer progression. Through extensive preclinical testing, Dr. Awadasseid evaluates the efficacy of these compounds, with a particular emphasis on their ability to target specific cancer pathways, including apoptosis, immune response modulation, and signal transduction. His research employs a wide range of molecular and biochemical techniques, including CRISPR/Cas9 gene editing, qPCR, flow cytometry, and various microscopy methods, to assess the therapeutic potential of novel compounds. Ultimately, Dr. Awadasseid aims to contribute to the development of more effective, targeted therapies for cancer patients.

Publication Top Notes:

  1. Design, synthesis and biological evaluation of novel TMPRSS2-PROTACs with florosubstituted 4-guanidino-N-phenylbenzamide derivative ligands. 🔬💊
  2. Design, synthesis, and evaluation of antitumor activity of 2-arylmethoxy-4-(2-fluoromethyl-biphenyl-3-ylmethoxy) benzylamine derivatives as PD-1/PD-L1 inhibitors. 🧬💥
  3. Small molecule and PROTAC molecule experiments in vitro and in vivo, focusing on mouse PD-L1 and human PD-L1 differences as targets. 🔬🐭
  4. Recent advances and mechanisms of action of PD-L1 degraders as potential therapeutic agents. 💡📚
  5. Design, synthesis, anti-tumor activity and mechanism of novel PROTACs as degraders of PD-L1 and inhibitors of PD-1/PD-L1 interaction. 🔧🎯
  6. Current studies and future promises of PD-1 signal inhibitors in cervical cancer therapy. 🎗️🔬
  7. A Review on the Anticancer Activity of Carbazole-based Tricyclic Compounds. 📖🔍
  8. Design, Synthesis, and Antitumor Activity Evaluation of 2-Arylmethoxy-4-(2, 2′-dihalogen-substituted biphenyl-3-ylmethoxy) Benzylamine Derivatives as Potent PD-1/PD-L1 Inhibitors. 🧪🧫
  9. PD-L1 dimerisation induced by biphenyl derivatives mediates anti-breast cancer activity via the non-immune PD-L1–AKT–mTOR/Bcl2 pathway. 🧬💥
  10. Design, synthesis and bioactivity of novel naphthalimide-benzotriazole conjugates against A549 cells via targeting BCL2 G-quadruplex and inducing autophagy. 🧪⚡

Conclusion:

Dr. Awadasseid is undoubtedly a strong candidate for the Best Researcher Award due to his exceptional contributions to the field of cancer research. His innovative approach to discovering therapeutic small-molecule compounds, coupled with his ability to collaborate across disciplines, positions him as a leader in the biochemistry and molecular biology community. By continuing to refine his research techniques and expanding his collaborations, Dr. Awadasseid is likely to further enhance the scope and impact of his work. His ultimate goal of improving patient care and treatment modalities places him in alignment with the mission of the Best Researcher Award, making him a fitting candidate for this prestigious recognition.