Ann-Kathrin Eisfeld | Molecular Profiles | Best Researcher Award

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Prof. Dr. Ann-Kathrin Eisfeld | Molecular Profiles | Best Researcher Award

The Ohio State University | United States

Dr. Ann-Kathrin Eisfeld is an internationally recognized physician-scientist and Associate Professor with Tenure in the Division of Hematology at The Ohio State University, where she also serves as Director of the Clara D. Bloomfield Center for Leukemia Outcomes Research. Her research focuses on the molecular and genetic underpinnings of acute myeloid leukemia (AML), with a particular emphasis on translational applications that improve patient outcomes. Dr. Eisfeld has published extensively in high-impact journals such as Nature, Leukemia, Blood, and Cell Stem Cell, contributing significantly to our understanding of leukemia biology, clonal evolution, and treatment resistance. she has authored over 100 peer-reviewed scientific publications, with an h-index of 38, more than 6,500 citations, and has led or co-led multiple collaborative studies within national consortia such as the Alliance for Clinical Trials in Oncology. Her work has identified critical biomarkers and therapeutic targets in AML, including insights into TP53 mutations, FLT3 alterations, and resistance mechanisms to venetoclax. Recognized for her integration of clinical insight with cutting-edge genomics, Dr. Eisfeld is a leading voice in precision oncology and leukemia research, shaping the future of individualized treatment strategies through both clinical innovation and scientific discovery.

Profile: Scopus

Featured Publications:

“Highly elevated serum hepcidin in patients with acute myeloid leukemia prior to and after allogeneic hematopoietic cell transplantation: Does this protect from excessive parenchymal iron loading?”

“Heritable polymorphism predisposes to high BAALC expression in acute myeloid leukemia”

“miR-3151 interplays with its host gene BAALC and independently affects outcome of patients with cytogenetically normal acute myeloid leukemia”

“Clinical and pharmacodynamic activity of bortezomib and decitabine in acute myeloid leukemia”

“Kinetics of iron removal by phlebotomy in patients with iron overload after allogeneic hematopoietic cell transplantation”

“inv(16)/t(16;16) acute myeloid leukemia with non-type A CBFB-MYH11 fusions associate with distinct clinical and genetic features and lack KIT mutations”

“Clinical Role of microRNAs in Cytogenetically Normal Acute Myeloid Leukemia: miR-155 Upregulation Independently Identifies High-Risk Patients”

“In rare acute myeloid leukemia patients harboring both RUNX1 and NPM1 mutations, RUNX1 mutations are unusual in structure and present in the germline”

“A stem cell-like gene expression signature associates with inferior outcomes and a distinct microRNA expression profile in adults with primary cytogenetically normal acute myeloid leukemia”

Afef Najjari | Bioinformatics | Women Researcher Award

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Assist. Prof. Dr. Afef Najjari | Bioinformatics | Women Researcher Award

Assist. Prof. Dr. Afef Najjari | Faculty of sciences of Tunisia/University of Tunis el Manar | Tunisia

Dr. Afef Najjari is an Assistant Professor in Biomedical Engineering, specializing in Bioinformatics at the Faculty of Sciences of Tunis. Her academic journey is marked by deep engagement in microbial genomics, with a particular focus on extremophilic microorganisms from the Tunisian desert. Dr. Najjari has authored over 17 peer-reviewed research papers and 2 book chapters, collaborating on international projects that explore genomics, environmental microbiology, and bioremediation. She has taught bioinformatics and genomics at institutions like ISBST and has mentored numerous master’s and PhD students. Her work contributes to understanding microbial diversity and biotechnological applications, particularly in arid ecosystems. With active involvement in teaching, supervision, and research, Dr. Najjari is a role model for young women entering STEM fields in Tunisia and beyond.

Publication Profile: 

Scopus

Education:

Dr. Najjari holds advanced degrees in Biological Sciences and Bioinformatics, culminating in a Ph.D. focused on microbial genomics and environmental microbiology. Her academic foundation combines traditional biology with computational and data-driven sciences. Though specific degree names or institutions aren’t listed, her roles in research and teaching suggest completion of doctoral training in a relevant biological discipline, followed by postdoctoral experience or academic training in genomics. Her integration into faculty positions at institutions such as the Faculty of Sciences of Tunis and ISBST further implies strong academic credentials, likely earned through nationally or internationally accredited programs. She effectively blends her biological background with technical bioinformatics applications, enabling interdisciplinary teaching and research.

Experience:

Dr. Najjari has over a decade of experience in academia, research, and mentorship. Since 2014, she has taught Genomics and Bioinformatics at ISBST and currently at the Faculty of Sciences of Tunis. She has supervised 11 graduate students across master’s and PhD levels. Her research centers on microbial genomics, metataxonomics, pan-genomics, and bioremediation, particularly in extreme environments like saline and geothermal oases. As an Assistant Professor in Biomedical Engineering, she skillfully integrates molecular biology with computational science. Beyond publishing in leading journals, she engages in collaborative, interdisciplinary research projects. Her dual role as educator and researcher allows her to train future bioinformaticians while advancing knowledge in microbial adaptation, iron uptake, and heavy metal remediation.

Research Focus:

Dr. Najjari’s research explores the genomic and functional diversity of extremophiles, focusing on halophilic archaea and bacteria from desert and saline ecosystems in Tunisia. She applies bioinformatics pipelines to understand microbial adaptation to harsh conditions, including iron uptake, oil degradation, and biopolymer production. Her projects use pan-genome analysis, 16S rRNA metataxonomics, and functional genomics to identify microbial traits valuable in bioremediation, such as flocculation of heavy metals and pesticides. Her work advances the understanding of environmental microbiomes and their industrial and ecological potential. Recently, she has extended her research to include the gut microbiome of honeybees and livestock genomics, contributing to biodiversity preservation. Her focus is timely and relevant, addressing global environmental challenges with sustainable biotechnological solutions.

Publications Top Notes:

  1. Genome and pan-genome analysis of Psychrobacillus sp. – Front. Microbiol.,

  2. Physiological and genomic insights into halophilic archaeon Natrinema altunense – Genetica,

  3. 16S rRNA phylogenetic diversity of archaeal communities in Saharan halite salts – Biology (Basel),

  4. Metataxonomics of Tunisian phosphogypsum using five bioinformatics pipelines – Genomics,

  5. Flocculating heteropolysaccharide–protein from haloarchaea for heavy metals removal – Environmental Technology,

  6. Genome analysis of Halomonas desertis G11 for oil degradation and biosurfactant production – Genomes,

  7. Pseudomonas rhizophila S211 for pesticide bioremediation and plant growth – Front. Microbiol.,

  8. Microbiota of whitefly Bemisia tabaci via 16S rDNA sequencing – Microbiology Research,

  9. Genome-wide selection scans in fat- vs. thin-tailed North African sheep – Animal Genetics,

  10.  Metataxonomic analysis of halophiles in geothermal oases of southern Tunisia – FEMS Microbiol. Lett.,

Conclusion:

Dr. Afef Najjari is a highly suitable candidate for the Research for Women Researcher Award. Her innovative research in bioinformatics and microbial genomics, particularly in extreme and underexplored ecosystems of Tunisia, not only advances scientific knowledge but also addresses pressing environmental challenges. Her dedicated teaching and supervision record, combined with her technical expertise, exemplify academic excellence and leadership. While expanding her engagement in women-focused STEM initiatives and international research programs could further amplify her impact, her existing contributions already position her as a key figure in North African science. Recognizing Dr. Najjari with this award would celebrate her scientific achievements and inspire broader participation of women in high-impact research fields.

Noura Hussein Abdel Hamid | Cell Structure Analysis | Best Researcher Award

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Assist. Prof. Dr. Noura Hussein Abdel Hamid | Cell Structure Analysis | Best Researcher Award

Assist. Prof. Dr. Noura Hussein Abdel Hamid , Zagazig University , Egypt

Dr. Noura Hussein Abedel Hamid Mekawy is a dedicated Egyptian medical academic with extensive expertise in Histology and Cell Biology. Born on April 18, 1981, she graduated with an M.B.B.Ch. from Zagazig University in 2006, followed by a Master’s (2012) and an M.D. (2017) in Histology and Cell Biology from the same institution. Currently, she serves as a Lecturer at Zagazig University’s Faculty of Medicine. Her academic journey is complemented by her passion for medical education, microscopy, and molecular research. Dr. Mekawy has contributed to the field with multiple publications in reputable scientific journals, focusing on histopathological and immunohistochemical studies. She is a member of the Egyptian Society of Histology and Cytology and has completed professional training in self-evaluation and quality assurance in higher education. Her commitment to scientific advancement and education has established her as a respected figure in medical academia.

Publication Profile:

Orcid

✅ Strengths for the Award:

  1. Extensive Research Background
    Dr. Mekawy has authored and co-authored 10 peer-reviewed publications, focusing on histopathology, immunohistochemistry, toxicology, and therapeutic interventions in experimental models.

  2. Specialization in a Vital Medical Field
    Her focus on Histology and Cell Biology is crucial for understanding disease mechanisms and developing new treatment strategies.

  3. Academic Progression & Teaching Role
    She has shown consistent career advancement from Demonstrator to Lecturer, demonstrating leadership and commitment in academia.

  4. Diverse Research Themes
    Her work explores the toxicological impacts of nanoparticles, pharmaceuticals, and environmental exposures, as well as the protective effects of antioxidants and stem cells—offering a well-rounded scientific profile.

  5. Professional Engagement
    Active member of Egyptian Society of Histology and Cytology and Medical Professions Syndicate, and involved in scientific conferences and training workshops.

  6. Methodological Strength
    Her skills in light/electron microscopy and immunohistochemical techniques indicate deep technical expertise.

⚙️ Areas for Improvement:

  1. Expand to International Collaborations
    Engaging in collaborative research with international institutions can increase visibility and impact.

  2. Publication in Higher Impact Journals
    While she has multiple publications, targeting high-impact Q1 journals can elevate the academic value of her research.

  3. Grant Funding & Project Leadership
    Applying for external research grants and leading funded projects would further enhance her research profile.

  4. Clinical Translation
    Bridging her findings from animal studies to clinical or translational research can broaden applicability.

🎓 Education:

Dr. Noura Mekawy earned her M.B.B.Ch. degree in Medicine and General Surgery from Zagazig University in October 2006, graduating with an excellent grade. Her strong academic foundation led her to pursue postgraduate studies in Histology and Cell Biology. In May 2012, she was awarded a Master’s degree with a thesis titled “The Effect of Maternal Exposure to Di (2-ethylhexyl) phthalate on The Lung of Albino Rat Offspring (Histological and Immunohistochemical Study).” She continued her academic progression by earning her M.D. in Basic Medical Sciences (Histology and Cell Biology) in January 2017. Throughout her studies, Dr. Mekawy demonstrated outstanding academic performance and developed a deep interest in cellular biology and histopathology. Her educational background reflects her commitment to advancing medical science through both practical research and academic instruction.

🧪 Experience:

Dr. Noura Mekawy began her academic career as a Demonstrator in the Histology and Cell Biology Department at Zagazig University in August 2008. She served in this role until May 2012, when she was promoted to Assistant Lecturer. In January 2017, following the completion of her M.D., she assumed the position of Lecturer in the same department. With over 15 years of experience in teaching and laboratory work, Dr. Mekawy has become proficient in histological techniques, immunohistochemistry, and electron microscopy. She is also skilled in data analysis using SPSS and Microsoft Office tools. Her responsibilities include teaching, supervising research projects, and contributing to curriculum development. Additionally, she has participated in educational quality assurance workshops and continues to mentor students and junior faculty members. Her teaching experience, combined with hands-on laboratory expertise, makes her a well-rounded educator and researcher.

🔬 Research Focus:

Dr. Mekawy’s research primarily focuses on histopathological and immunohistochemical changes in response to environmental, chemical, and pharmaceutical exposures in animal models. Her investigations are centered on understanding tissue damage and repair mechanisms in organs like the liver, lungs, testes, heart, submandibular glands, and the central nervous system. A consistent theme across her work is evaluating the protective or therapeutic roles of natural substances and pharmacological agents, including antioxidants like Vitamin E, Nigella sativa, and Zingerone, as well as advanced treatments such as salivary exosomes and stem cells. She integrates light microscopy, electron microscopy, and molecular biology techniques in her research. Dr. Mekawy is also engaged in evaluating the histological effects of nanoparticles and energy drinks on various tissues. Her contributions are valuable for toxicological assessment and potential therapeutic innovations, contributing to public health and medical safety.

📚 Publications Top Notes:

  1. 🧪 Effect of Silver Nanoparticles on Testes of Prepubertal Male Albino Rats and the Possible Protective Role of Vitamin E

  2. ⚠️ Hepatic Changes under the Effect of Red Bull Energy Drinks and its Withdrawal in Adult Male Albino Rats

  3. 💧 Therapeutic Role of Salivary Exosomes in Improving Histological and Biochemical Changes Induced by Duct Ligation in Submandibular Glands

  4. ❤️ The Possible Protective Effect of Zingiber Officinale on Cyclophosphamide-Induced Cardiotoxicity

  5. 👁️ Protective Effect of Chrysin on Corneal Structural Alterations Induced by Sofosbuvir

  6. 🧬 Nicorandil and Bone Marrow-Derived Mesenchymal Stem Cells in Ureteric Obstruction Recovery

  7. 🧠 Effect of Zinc Oxide Nanoparticles on Cerebellar Cortex of Adult Male Albino Rats

  8. 🥼 Protective Role of Ghrelin versus its Combination with Zingerone on Gastric Ischemic-Reperfusion

  9. 🔊 Effect of Low Frequency Noise on Heart and Lung & Role of Vitamin C

  10. 💪 Nandrolone Effect on Cardiac Muscle and Role of Nigella Sativa

🧾 Conclusion:

Dr. Noura Mekawy exhibits the hallmarks of a dedicated, capable, and innovative researcher in medical science. With over a decade of academic and research experience, she has made valuable contributions to experimental histology and cell biology. Her work is methodologically sound, thematically diverse, and medically relevant. The strength of her research, consistent publication record, and academic integrity make her a highly suitable candidate for the Best Researcher Award. Continued growth in publication quality, global collaboration, and translational research will further enhance her already impressive academic journey.