Dominique Heymann | Cancer Cell Biology | Best Researcher Award

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Prof. Dr. Dominique Heymann | Cancer Cell Biology | Best Researcher Award

Prof. Dr. Dominique Heymann , Nantes Université, CNRS, Institut de Cancérologie de l”Ouest , France

Professor Dominique Heymann is a highly esteemed academic and clinician, specializing in histology, embryology, and oncology. He is a Professor at Nantes University, France, and a Hospital Practitioner at the ICO Cancer Centre. With a wealth of experience in bone oncology and cancer research, he is also an Honorary Professor at the University of Sheffield, UK. His expertise spans from cell biology to immunology and biochemistry, and he is dedicated to advancing cancer research, particularly in the field of bone tumors and osteosarcoma. With numerous publications to his name and contributions to the global scientific community, Professor Heymann is recognized for his groundbreaking work in cell signaling and tumor progression. He is a valued researcher in the oncology community, with a strong focus on developing innovative therapies for cancer treatment.

Publication Profile:

Google Scholar

Strengths for the Award:

Professor Dominique Heymann is a distinguished figure in the field of oncology, particularly bone oncology, with a strong focus on the molecular mechanisms of bone tumors like osteosarcoma. His academic and clinical roles at the University of Nantes and the ICO Cancer Centre underscore his leadership in research and patient care. He has contributed significantly to understanding tumor biology, bone remodeling, and regenerative medicine, making him a highly respected expert in these fields. His research addresses crucial topics such as circulating tumor cells, targeted therapies, and the development of new anticancer agents, all of which are of immense value to advancing cancer treatment. With multiple publications in prestigious journals, including studies on novel therapies and molecular pathways in cancer progression, Professor Heymann has demonstrated exceptional scientific rigor. His global collaborations and recognition further establish him as a leading researcher in cancer biology and oncology.

Areas for Improvements:

Despite his numerous contributions, there are a few areas where Professor Heymann’s research could evolve. While he has made notable strides in cancer treatment and bone oncology, expanding research into more personalized medicine approaches and exploring the integration of AI and machine learning in predictive oncology could enhance the applicability of his findings. Furthermore, increasing collaborative efforts with international interdisciplinary teams could yield broader insights, especially in rare cancers and metastasis research. Developing a more extensive outreach to clinical trials and collaborations in broader regions may also allow for faster translation of his research into practice.

Education:

Professor Heymann began his academic journey at Paris VII University, where he earned a Master’s degree in Cell Biology in 1991. His PhD in Cell Biology and Immunology was completed at Nantes University in 1995, a pivotal moment in his career. Further expanding his knowledge, he pursued research management abilities and a deeper focus on Biochemistry and Cell Biology at Nantes University in 1998. He also received specialized certification in Histology from Nantes University in 1999 and later completed the required authorizations for animal experimentation in 2003 and 2016. Throughout his academic career, Professor Heymann has continually updated his qualifications, ensuring his expertise remains at the cutting edge of medical and biological sciences. His academic foundation has underpinned his significant contributions to cancer research, with a strong emphasis on bone oncology and regenerative medicine.

Experience:

Professor Dominique Heymann has an extensive and diverse career spanning several decades in both academic and clinical settings. Currently, he serves as a Professor of Histology/Embryology at Nantes University and as a Hospital Practitioner at the ICO Cancer Centre, where he is instrumental in patient care and research. His professional trajectory includes significant roles in oncology, particularly focused on bone tumors, osteosarcoma, and regenerative medicine. As an Honorary Professor at the University of Sheffield, he extends his influence beyond France, fostering international collaboration in cancer research. Professor Heymann has been a prominent figure in multiple research projects, having managed and contributed to groundbreaking studies. His expertise in cancer biology, combined with his academic roles, has allowed him to mentor students and researchers, shaping the next generation of scientists. His dual role in academia and clinical practice makes him a leading figure in both spheres.

Awards and Honors:

Professor Dominique Heymann’s career is adorned with numerous accolades and honors. As a tenured professor at the University of Nantes, he has received recognition for his contributions to histology, embryology, and oncology. He was appointed as an Honorary Professor in Bone Oncology at the University of Sheffield, UK, an esteemed acknowledgment of his expertise in the field. His work in cancer research, particularly related to bone tumors, has earned him international recognition, and his published studies continue to be highly regarded in scientific journals. Additionally, Professor Heymann has contributed significantly to the understanding of osteosarcoma and bone regeneration, which has earned him awards from academic and clinical societies. His continuous impact in advancing the field through groundbreaking research, leadership in clinical oncology, and educational contributions has made him a highly respected figure in the medical and scientific communities.

Research Focus:

Professor Dominique Heymann’s research is focused on cancer, particularly bone tumors such as osteosarcoma, and the molecular mechanisms involved in bone regeneration. His work primarily investigates the signaling pathways that control bone remodeling, the interactions between tumor cells and the microenvironment, and the role of immune responses in bone diseases. One of his key research interests is the development of targeted therapies to combat cancer progression, with a special emphasis on novel anticancer agents, including glycosaminoglycan-mimetic compounds derived from marine bacterial exopolysaccharides. In addition, Professor Heymann is dedicated to studying the role of circulating tumor cells as predictive markers for drug resistance and tumor progression. His expertise also includes stem cell therapies, autophagy in osteoblasts, and the potential for therapeutic applications in bone repair and regeneration. His research aims to improve patient outcomes through innovative approaches in cancer treatment and bone health.

Publications Top Notes:

  • Heymann D, Muñoz-Garcia J, Babuty A, et al. A new promising anticancer agent: a glycosaminoglycan-mimetic derived from the marine bacterial infernan exopolysaccharide. Int J Biol Macromol. (in press) 🧬

  • Jacquot P, Muñoz-Garcia J, Léger A, et al. A multispecific checkpoint inhibitor Nanofitin with a fast tumor accumulation property and antitumor activity in immune competent mice. Biomolecules. (in press) 🔬

  • Yadav P, Heymann D, Prasad RN. Circulating tumor cells: a predictive marker for drug resistance and tumor progression. Front Oncol. (in press) 🔬

  • Muñoz-Garcia J, et al. Interleukin-34 orchestrates bone formation through its binding to Bone Morphogenic Proteins. Theranostics. 2025; 15(7):3185-3202. 🦴

  • Young RJ, et al. CIRCUS: CIRCUlating tumor cells in soft tissue Sarcoma – a short report. Cancer Drug Resist. 2022; 4:51. 💉

  • Oliver L, et al. Transcriptional landscape of the interaction of human mesenchymal stem cells with glioblastoma in bioprinted co-cultures. Stem Cell Res Ther. 2024; 15(1):424. 🧫

  • Cordova LA, et al. Why are osteoporosis patients treated with antiresorptive therapies considered like oncology patients regarding their oral health care? Osteoporos Int. 2024; 35(9):1677-1678. 🦷

  • Childs A, et al. A prospective observational cohort study for newly diagnosed patients in the UK: ICONIC study initial results. Cancers (Basel). 2024; 16(13):2351. 📊

  • Rey V, et al. A personalized medicine approach identifies enasidenib as an efficient treatment for IDH2 mutant chondrosarcoma. EBioMedicine. 2024; 102:105090. 🧬

  • Jubelin C, et al. Identification of MCM4 and PKRDC as new regulators of osteosarcoma cell dormancy based on 3D cultures. BBA Mol Cell Res. 2024; 1871:119660. 🧪

Conclusion:

Professor Dominique Heymann’s expertise in oncology, histology, and embryology positions him as an outstanding candidate for the Research for Best Researcher Award. His achievements in cancer research, particularly in bone tumors, and his contributions to advancing the understanding of tumor biology make him an exemplary figure. While there are areas to expand in terms of interdisciplinary collaborations and technological integration, his exceptional body of work and his dedication to both academic excellence and clinical practice make him a deserving candidate for this prestigious award.

Peter du Plessis | Cancer Cell Biology | Best Researcher Award

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Mr. Peter du Plessis | Cancer Cell Biology | Best Researcher Award

Mr. Peter du Plessis , iThemba LABS , South Africa

Peter Clark du Plessis is an accomplished professional with a robust background in radiotherapy and oncology. His career spans over two decades, starting as a Radiation Therapist and Researcher at iThemba LABS since 2006. He is dedicated to both teaching and research, fostering critical thinking and academic growth among students. Apart from his academic contributions, Peter is passionate about mentoring and enjoys long walks and playing chess in his spare time. With a string of accolades, including Director’s Special Awards in 2012 and 2014, he consistently demonstrates excellence in his field. He is committed to inspiring the next generation of healthcare professionals through hands-on experience, leadership, and a deep passion for his profession.

Publication Profile:

Orcid

Strengths for the Award:

Peter Clark du Plessis exemplifies the qualities of a leading researcher in radiotherapy and oncology, making him highly suitable for the Best Researcher Award. His career spans over two decades, showcasing not only professional expertise but a commitment to advancing cancer treatment through research. Peter has a wealth of hands-on experience, holding key roles at iThemba LABS, where his research continues to shape the field of hypofractionated radiotherapy for breast and prostate cancers. His mentorship and dedication to teaching further highlight his influence on future healthcare professionals. Additionally, his accolades, including two Director’s Special Awards, demonstrate a history of excellence and recognition from peers in his field. Peter’s work also bridges research and practice, contributing significantly to improving radiotherapy techniques for cancer patients.

Areas for Improvement:

Although Peter’s achievements are commendable, his research could benefit from increased international collaborations to diversify research perspectives and data. Further partnerships with global research institutions could strengthen the practical impact of his findings, particularly in addressing diverse patient needs in different populations. Expanding his visibility in clinical trials and engaging with other healthcare sectors could further solidify his standing as a leader in oncology research.

Education (150 words):

Peter Clark du Plessis is currently pursuing a Doctorate in Radiography (DRRAD) at the Durban University of Technology, focusing on the hypofractionated radiotherapy for breast and prostate cancer (2022-2024). He holds a Master’s degree in Radiography from the Cape Peninsula University of Technology (2017-2018), with research on radiosensitivity variations in breast cancer cells. Peter earned his Bachelor of Technology in Radiography (cum laude) in 2010 and a National Diploma in Therapeutic Radiography in 1997, both from Cape Peninsula Technikon. Additionally, he began studying Computer Science at the University of the Western Cape but did not complete the degree. His academic journey highlights his passion for improving patient care and advancing cancer treatment techniques, including his research on proton beam therapies. Peter’s ongoing research aligns with his deep commitment to enhancing oncology practices through both theoretical and practical contributions.

Experience (150 words):

Peter has a comprehensive professional history, notably as a Radiation Therapist and Researcher at iThemba LABS since 2006. Here, he has been at the forefront of advancements in radiation therapy and oncology research. Prior to that, he held positions at the Provincial Hospital in Port Elizabeth as Chief Radiation Therapist (2006) and at King Abdul-Aziz Medical City as a Mould Room Technician and Radiation Therapist (2003-2005). His teaching experience is equally impressive, having served as a lecturer and moderator at Cape Peninsula University of Technology and North West University since 2019. He has contributed to health science research courses, specifically focusing on data analysis, publications, and radiation therapy practice. His multifaceted roles in both academic and clinical settings have honed his skills in education, research, and professional development. Peter’s work has had a significant impact on radiotherapy practices and student education, particularly in the field of cancer treatment.

Awards and Honors (150 words):

Peter Clark du Plessis has received multiple awards, demonstrating his dedication and excellence in the field of radiotherapy. Most notably, he was honored with two Director’s Special Awards at iThemba LABS in 2012 and 2014, recognizing his outstanding contributions to research and clinical advancements in radiation therapy. These accolades affirm his deep commitment to both research and the application of radiotherapy techniques, specifically in cancer treatment. His work in radiotherapy has helped bridge theoretical knowledge with real-world practice, particularly in advanced cancer therapies like proton beam treatments. Peter’s passion for the field and ability to integrate research with clinical practices has been acknowledged throughout his career, making him a key figure in advancing healthcare practices. His recognition reflects the impact of his research and teaching on future healthcare professionals in the radiation therapy domain.

Research Focus (150 words):

Peter Clark du Plessis focuses on exploring and advancing radiotherapy techniques, particularly in the context of hypofractionated radiotherapy for breast and prostate cancer. His research delves into the efficacy and molecular mechanisms of these treatments, especially using proton beam therapy. With a strong foundation in radiobiology, his work investigates the variation in radiosensitivity between different cancer and normal cell types, with a particular interest in breast cancer. Peter’s research aims to improve patient outcomes by refining radiotherapy protocols, making cancer treatment more effective and personalized. His contributions are significant in bridging the gap between laboratory research and clinical practices. Peter’s goal is to inspire new approaches in cancer care by combining in vitro studies with clinical observations. His ongoing work at iThemba LABS and various academic institutions positions him at the forefront of research into innovative radiotherapy solutions.

Publications (Titles with Emojis):

  • Exploring Hypofractionated Radiotherapy Efficacy in Prostate Cancer: In Vitro Insights 🧑‍🔬📚
  • In Vitro Perspective on Hypofractionated Radiotherapy in Breast Cancer 🧑‍🔬📚
  • Immunological Changes During Space Travel: A Ground-Based Evaluation of the Impact of Neutron Dose Rate on Plasma Cytokine Levels in Human Whole Blood Cultures 🌌💉
  • The Impact of Dose Rate on DNA Double-Strand Break Formation and Repair in Human Lymphocytes Exposed to Fast Neutron Irradiation 🧬⚛️

Conclusion:

Peter Clark du Plessis is a remarkable candidate for the Best Researcher Award due to his extensive experience, impressive body of research, and dedication to advancing radiotherapy practices. His work continues to impact the field of oncology positively, offering new insights into cancer treatment methodologies. With continued growth in research collaboration and global outreach, Peter is poised to further enhance his contributions to the field of radiotherapy.

 

 

 

Li Hou | Cancer Cell Biology | Best Researcher Award

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Prof. Li Hou | Cancer Cell Biology | Best Researcher Award

Prof. Li Hou , Department of Oncology and Hematology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 100700, China

Li Hou is a distinguished Chief Physician and Director of the Hematology and Oncology Department at Dongzhimen Hospital, affiliated with Beijing University of Chinese Medicine. With a career spanning over 30 years, she has made remarkable contributions in the integration of Traditional Chinese Medicine (TCM) and Western Medicine for treating tumors and blood diseases. A renowned researcher and educator, Hou Li has led over 40 research projects, authored 50+ papers, and published significant work on tumor and blood disease therapies. Her expertise has been recognized with the prestigious “Famous Doctor’s Excellent Demeanor Award” in 2018. Her passion for advancing healthcare through combined approaches has made her a leader in oncology and hematology in China and internationally. 🌟🎓💉

Publication Profile:

Orcid

Strengths for the Award:

Dr. Li Hou is highly deserving of the Best Researcher Award due to her exceptional contributions in integrating Traditional Chinese Medicine (TCM) and Western Medicine for the treatment of hematological diseases and cancers. Her career is distinguished by over 40 research programs and more than 50 published papers, demonstrating her expertise in oncology and hematology. She has authored notable articles in high-impact journals, showcasing her deep understanding of tumor biology and blood disorders. Her leadership in research, coupled with her clinical practice, has led to groundbreaking insights into the treatment of malignancies, including her work on identifying novel drug targets for cancers. Furthermore, her role in academia and professional service, as a key figure in several influential medical associations, highlights her outstanding impact in the medical field. 🌟🧑‍🔬📚

Areas for Improvement:

While Dr. Li Hou research achievements are commendable, expanding her research collaborations internationally could further enhance her impact. Engaging with global research communities may foster new perspectives and facilitate the exchange of ideas, particularly in the context of cutting-edge medical technologies. Additionally, expanding research into the long-term outcomes of integrated therapies in various populations could provide further evidence of the benefits of combining TCM with Western approaches. This would allow her work to gain even more recognition and clinical application worldwide. 🌍🔬

Education:

Li Hou completed her Bachelor’s in Chinese Medicine at Beijing University of Chinese Medicine in 1993. She then pursued her Master’s degree in Integrated Chinese and Western Medicine from the same institution, completing it in 1998. In 2004, she earned her Doctorate in Integrated Chinese and Western Medicine. Her academic journey has been rooted in the application of both traditional and modern methods to treat complex diseases like cancer and blood disorders, providing her with a strong foundation for her career in clinical practice, research, and education. 🎓📚🩺

Experience:

Li Hou clinical career began in 1993 as a resident at Dongzhimen Hospital. By 1999, she advanced to attending physician, and by 2008, she became an associate chief physician. In 2013, she was appointed as Chief Physician at Dongzhimen Hospital, where she has been working ever since. She holds significant leadership roles within the field, including Chairman of several prestigious oncology committees. Additionally, her role as an evaluation expert for the National Natural Science Foundation of China demonstrates her expertise in research. She has been instrumental in combining traditional Chinese medicine with modern treatments in the management of cancer and hematological conditions. 🏥💼👩‍⚕️

Research Focus:

Li Hou research focus revolves around the integration of Traditional Chinese Medicine (TCM) and Western medicine to treat hematological diseases and cancer. She has made significant strides in identifying novel therapeutic approaches, with an emphasis on improving cancer treatment outcomes. Her work includes studying the role of TCM in modulating drug responses and enhancing chemotherapy effectiveness. Through her extensive research, she has contributed to understanding the genetic and molecular mechanisms involved in blood cancer and tumor progression, aiming to optimize patient care and survival rates. Her studies have been published in leading medical journals. 🧬🔬💡

Publications Top Notes:

  • Identification of potential drug targets for four site-specific cancers by integrating human plasma proteome with genome – Journal of Pharmaceutical and Biomedical Analysis (2025)
  • Genetic analysis from multiple cohorts implies causality between 2200 druggable genes, telomere length, and leukemia – Computers in Biology and Medicine (2024)
  • Genetically predicted 486 blood metabolites in relation to risk of colorectal cancer: A Mendelian randomization study – Cancer Medicine (2023)
  • Improvement of Early Death in Acute Promyelocytic Leukemia: A Population-Based Analysis – Clinical Lymphoma Myeloma and Leukemia (2023)
  • Tanshinone IIa Induces Autophagy and Apoptosis via PI3K/Akt/mTOR Axis in Acute Promyelocytic Leukemia NB4 Cells – Evidence-Based Complementary and Alternative Medicine (2021)
  • Effectiveness of Acupuncture Treatment on Chemotherapy-Induced Peripheral Neuropathy: A Pilot, Randomized, Assessor-Blinded, Controlled Trial – Pain Research and Management (2020) 📝📚🎯

Conclusion:

Dr. Li Hou contributions to medicine are profound and multifaceted, blending traditional and modern therapeutic approaches to offer innovative solutions for cancer and blood diseases. Her research has not only advanced scientific knowledge but also improved patient care. As a leader in both clinical practice and research, she exemplifies the qualities of a Best Researcher Award recipient. Through her continued dedication to her work, Dr. Hou Li will undoubtedly remain at the forefront of medical research, driving progress in both China and globally. 🏆💉🩺