Prof. Dr. Hongliang Xin | Tissue Engineering Regeneration | Best Researcher Award

Prof. Dr. Hongliang Xin, Nanjing Medical University, China

Professor Hongliang Xin is a distinguished pharmaceutical scientist at Nanjing Medical University, China. After earning his PhD from Fudan University in 2011, he joined Nanjing Medical University and rapidly rose through academic ranks, becoming a full professor by 2020. His international experience includes a research fellowship at North Carolina State University (2015–2016), enriching his global academic outlook. Professor Xin has made significant contributions in drug delivery, particularly for brain disorders and cancer. His work on biomimetic nanoparticles and dual-targeting systems has been widely recognized, with several of his publications cited hundreds of times. He is a recipient of the Jiangsu Outstanding Research Award and has contributed to translational science through interdisciplinary collaboration. Committed to innovation in intelligent drug delivery, Professor Xin continues to push boundaries in nanomedicine. His dedication and impactful research make him a strong candidate for the Best Researcher Award.

Publication Profile: 

Google Scholar

✅ Strengths for the Award:

1. Innovative Research in Drug Delivery
   Prof. Xin has led pioneering work in cellular biomimetic drug delivery systems and brain-targeted therapies, particularly utilizing Angiopep-conjugated and ROS-responsive nanoparticles. His research shows deep innovation in crossing the blood-brain barrier — a major challenge in neuroscience and oncology.

2. Strong Publication Record
   He has authored multiple high-impact publications in top-tier journals such as Biomaterials, ACS Nano, and Advanced Materials. Several of these works have citations exceeding 300–400, indicating significant influence in the scientific community.

3. International Research Exposure
   His experience as a visiting scholar at North Carolina State University reflects a global approach to science, enhancing both the breadth and depth of his research collaborations.

4. Consistent Career Growth
   From lecturer to professor within a decade, Prof. Xin’s steady academic rise reflects both merit and dedication.

5. Recognition and Awards
   Recipient of the Jiangsu Outstanding Research Award, validating his contributions at the provincial and national level.

⚙️ Areas for Improvement:

1. Clinical Translation
   While preclinical research is robust, moving towards clinical trials or commercial partnerships would greatly strengthen the translational impact of his work.

2. Leadership in International Consortia
   Increased participation or leadership in global research initiatives, conferences, or consortia could further elevate his visibility and impact internationally.

3. Cross-Disciplinary Outreach
   Expanding collaborations into neuropsychology, regenerative medicine, or pharmaceutical industry applications could broaden the application of his delivery systems.

🎓 Education:

Hongliang Xin completed his doctoral studies in Pharmacy at Fudan University in 2011, one of China’s most prestigious universities. His academic journey was grounded in pharmaceutical sciences, focusing on drug delivery systems and nanotechnology-based therapies. During his PhD, he laid the foundation for his future research in targeted therapy and biomimetic materials. Post-PhD, he expanded his academic training internationally as a visiting scholar at North Carolina State University in the United States (2015–2016). This exposure to global research trends and interdisciplinary approaches further honed his expertise. The integration of chemical engineering, pharmacology, and nanotechnology into his educational training has allowed him to develop innovative and effective therapeutic strategies for brain-targeted drug delivery. His education has not only equipped him with strong technical skills but also with a visionary approach to translational medicine.

🧪 Experience:

Dr. Hongliang Xin began his academic career as a lecturer at Nanjing Medical University’s School of Pharmacy in 2011. He was promoted to Associate Professor in 2015 and became a Full Professor in 2020. Over the years, he has built a robust research program in nanomedicine and drug delivery, leading multiple funded projects and mentoring graduate students. His one-year tenure as a visiting scholar at North Carolina State University provided him international collaborative opportunities, boosting his cross-disciplinary competence. Professor Xin has published extensively in high-impact journals such as Biomaterials, ACS Nano, and Advanced Materials. He is also a recognized leader in translational drug delivery platforms, specifically for brain diseases and cancer. His extensive teaching, grant acquisition, and collaborative research background reflect both academic maturity and innovation. His professional journey exemplifies excellence, persistence, and a global perspective on healthcare research.

🔬 Research Focus:

Professor Hongliang Xin’s research centers on cellular biomimetic drug delivery systems and intelligent therapeutic strategies for brain diseases such as glioblastoma and ischemic stroke. His work integrates polymer chemistry, pharmacokinetics, and molecular targeting to design nanoparticles that can cross the blood-brain barrier with precision. A key innovation in his research is the use of Angiopep-conjugated polymers and ROS-responsive carriers to ensure site-specific and safe drug delivery. His dual-targeting PEG-PCL nanoparticle system has shown remarkable results in preclinical models of brain cancer, while his transcutaneous immunotherapy approach enhances anti-tumor immunity. Professor Xin’s focus also extends to thrombolytic delivery systems, neuroprotectants, and engineered nano-platelets for hematologic malignancies. With over a decade of focused work, his lab continues to address clinical challenges in oncology and neurology, aiming to translate nanoscale innovations into real-world therapeutics.

📚 Publications Top Notes:

1. 🧠💊 Angiopep-conjugated PEG-PCL nanoparticles as dual-targeting system for brain glioma

2. 🧬🛡 Anti-glioblastoma efficacy of paclitaxel-loaded Angiopep-conjugated PEG-PCL nanoparticles

3. 💉🧫 Synergistic transcutaneous immunotherapy for checkpoint inhibitor delivery and tumor response

4. 🧠🎯 2-deoxy-D-glucose functionalized PEG-PTMC nanoparticles for glioma targeting

5. 🧠⚡ Boronic ester-dextran polymer nanoparticles responsive to ROS for stroke therapy

6. 🧫🩸 Nano-platelets for enhanced treatment of multiple myeloma and thrombus

7. 🧠🧬 Site-specific delivery of thrombolytics and neuroprotectants for ischemic stroke

8. 🧠🧪 Brain targeting mechanism of Angiopep-conjugated PEG-PCL nanoparticles

9. 🧠💉 Dual-targeted nanocarrier for treatment of brain ischemic stroke

10. 💊🧠 Integrin-mediated PEG-PTMC nanoparticles for solid tumor penetration and paclitaxel delivery

🧾 Conclusion:

Professor Hongliang Xin is a highly qualified and impactful researcher whose contributions in intelligent, targeted drug delivery—especially for brain diseases—are both scientifically innovative and socially relevant. His work bridges critical gaps in nanomedicine and therapeutic targeting, and his publications are widely cited, reflecting broad recognition. With strategic focus on clinical translation and deeper global engagement, his already excellent profile could reach even greater heights.