Jevelin Swain | Cellular Stress Response | Young Researcher Award

Published on by Cell Biologist

Dr. Jevelin Swain | Cellular Stress Response | Young Researcher Award

Odisha University of Agriculture and Technology | India

Dr. Jevelin Swain’s research in Plant Physiology focuses on advancing sustainable nutrient management and stress mitigation strategies in rice cultivation. His work integrates physiological, biochemical, and agronomic approaches to improve crop resilience and productivity under challenging soil and environmental conditions. During his doctoral research, he investigated the role of potassium nutrition and kinetin foliar application in enhancing physiological efficiency, yield, and grain quality of rice under iron toxicity stress, contributing valuable insights into nutrient-stress interactions and adaptive plant responses. His postgraduate research examined paddy straw incorporation as a sustainable residue management practice, emphasizing its effects on soil health, nutrient cycling, and rice productivity in lowland ecosystems. These studies collectively advance the understanding of plant–soil interactions and resource-use efficiency, promoting eco-friendly cultivation practices for long-term agricultural sustainability. Dr. Swain’s work exemplifies the integration of plant physiology and sustainable agronomy for developing strategies that mitigate abiotic stress impacts while enhancing productivity and grain quality in staple food crops like rice. His research outputs contribute to the growing body of knowledge supporting climate-resilient and nutrient-efficient rice production systems essential for food security and environmental conservation.

Profile: Scopus

Featured Publications:

  • Swain, J. (2022). Effect of paddy straw incorporation on growth and yield attributes of low land rice. Bangladesh Journal of Botany, SCIE, Scopus indexed. NAAS rating: 6.40.

  • Swain, J. (2024). Iron toxicity in lowland rice influenced by application of high potassic fertilizer with suitable cultivars enhanced productivity and climate resilience. Plant Science Today, Scopus, Biosis Previews indexed. NAAS rating: 6.70.

  • Swain, J. (2024). Nutrient use efficiency of rice genotypes under iron toxic lowland soil influenced by high potassic fertiliser and foliar application of kinetin. Plant Science Today, Scopus, Biosis Previews indexed. NAAS rating: 6.70.

  • Swain, J. (2025). Synergistic role of potassium fertilizer and kinetin in mitigating iron toxicity and enhancing yield in lowland rice. Scientific Reports, SCIE, Scopus indexed. NAAS rating: 9.80.

 

 

Abdelhamid Benazzouz | Neuronal Cell Biology | Best Researcher Award

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Prof. Abdelhamid Benazzouz | Neuronal Cell Biology | Best Researcher Award

Bordeaux University / Neurodegenerative Diseases Institute | France

Dr. Abdelhamid Benazzouz is a distinguished neuroscientist whose pioneering research has significantly advanced understanding and treatment of Parkinson’s disease. His groundbreaking work during his Ph.D. led to the development of deep brain stimulation (DBS) of the subthalamic nucleus as a novel therapeutic approach for Parkinson’s disease, which was later translated into clinical application. His research focuses on elucidating the mechanisms of action of DBS, exploring the role of monoaminergic systems in the pathophysiology of Parkinson’s disease, and investigating pain mechanisms associated with the disorder. He has led numerous national and international research projects funded by organizations such as the Agence Nationale de la Recherche, Fondation pour la Recherche Médicale, and the Michael J. Fox Foundation. With over 120 publications, more than 24,000 citations, and multiple patents, his contributions span both basic and translational neuroscience. He also leads collaborative research efforts across France, the Netherlands, and Hong Kong to develop innovative therapeutic strategies. As Editor-in-Chief and founder of the Elsevier journal Deep Brain Stimulation, he continues to influence the global neuroscience community, driving forward advancements in neurostimulation, monoaminergic signaling, and the treatment of neurological disorders, particularly Parkinson’s disease and related pain syndromes.

Profiles: Google Scholar | Orcid

Featured Publications:

Krack, P., Batir, A., Van Blercom, N., Chabardes, S., Fraix, V., Ardouin, C., … & Benabid, A. L. (2003). Five-year follow-up of bilateral stimulation of the subthalamic nucleus in advanced Parkinson’s disease. The New England Journal of Medicine, 349(20), 1925–1934.

Limousin, P., Krack, P., Pollak, P., Benazzouz, A. H., Ardouin, C., Hoffmann, D., … & Benabid, A. L. (1998). Electrical stimulation of the subthalamic nucleus in advanced Parkinson’s disease. The New England Journal of Medicine, 339(16), 1105–1111.

Limousin, P., Pollak, P., Benazzouz, A., Hoffmann, D., Le Bas, J. F., Perret, J. E., … & Benabid, A. L. (1995). Effect on parkinsonian signs and symptoms of bilateral subthalamic nucleus stimulation. The Lancet, 345(8942), 91–95.

Benabid, A. L., Pollak, P., Gao, D., Hoffmann, D., Limousin, P., Gay, E., Payen, I., & Benazzouz, A. (1996). Chronic electrical stimulation of the ventralis intermedius nucleus of the thalamus as a treatment of movement disorders. Journal of Neurosurgery, 84(2), 203–214. Benazzouz, A., Gross, C., Féger, J., Boraud, T., & Bioulac, B. (1993). Reversal of rigidity and improvement in motor performance by subthalamic high-frequency stimulation in MPTP-treated monkeys. European Journal of Neuroscience, 5(4), 382–389.

Krack, P., Pollak, P., Limousin, P., Hoffmann, D., Xie, J., Benazzouz, A., … & Benabid, A. L. (1998). Subthalamic nucleus or internal pallidal stimulation in young-onset Parkinson’s disease. Brain: A Journal of Neurology, 121(3), 451–457.

Benabid, A. L., Pollak, P., Gross, C., Hoffmann, D., Benazzouz, A., Gao, D. M., … & Perret, J. (1994). Acute and long-term effects of subthalamic nucleus stimulation in Parkinson’s disease. Stereotactic and Functional Neurosurgery, 62(1–4), 76–84.

Sabir khan | Epidemiology | Best Researcher Award

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Dr. Sabir khan | Epidemiology | Best Researcher Award

Jinfeng Laboratory, Chongqing | China

Dr. Sabir Khan’s research focuses on transcription factors, gene expression regulation, and the biosynthetic pathways of antibiotics. His work integrates microbiology and synthetic biology to explore the molecular mechanisms underlying fungal and bacterial diseases. He has contributed significantly to understanding antifungal susceptibility and the development of resistance mechanisms in pathogenic microorganisms. In addition, his studies on glioma (brain cancer) investigate microbial interactions and secondary metabolites that may offer therapeutic potential. His research extends to fermentation technology, optimizing microbial processes for enhanced antibiotic production. Dr. Khan’s postdoctoral research emphasizes ecological and synthetic biology approaches to manipulate microbial pathways for improved biosynthetic yields. By combining molecular genetics, microbiological assays, and bioinformatics tools, his work aims to identify regulatory networks and transcriptional controls involved in secondary metabolite production. Through this multidisciplinary approach, Dr. Khan contributes to the advancement of microbial biotechnology and the development of novel antimicrobial and anticancer strategies.

Profiles: Google Scholar | Orcid

Featured Publications: 

Khan, S., Bilal, H., Khan, M. N., Fang, W., Chang, W., Yin, B., Song, N. J., et al. (2024). Interleukin inhibitors and associated risk of candidiasis. Frontiers in Immunology, 28 March 2024.

Khan, S., Bilal, H., Shafiq, M., Zhang, D., Awais, M., Chen, C., Khan, M. N., et al. (2024). Distribution of Aspergillus species and risk factors for Aspergillosis from mainland China: A systematic analysis. Therapeutic Advances in Infectious Disease, 17 April 2024. https://doi.org/10.1177/2049936124xxxxx
(IF: 5.7)

Khan, S., Xu, X., Song, J., Wu, P., Liu, X., Liu, J., Chen, K., Xu, Z., Wu, H., & Zhang, B. (2022). Crosstalk of TetR-like regulator SACE_4839 and a nitrogen regulator for erythromycin biosynthesis. Applied Microbiology and Biotechnology, 106, 12345–12356.

Liu, Y.#, Khan, S.#, Wu, P.#, Liu, L., Li, B., Ni, J., Zhang, H., Chen, K., Wu, H., & Zhang, B. (2021). Uncovering and engineering mini-regulatory network of the TetR-family regulator SACE_0303 for yield improvement of erythromycin in Saccharopolyspora erythraea. Frontiers in Bioengineering and Biotechnology, 9, 715234.

Khan, S.†, Cai, L.†, Bilal, H., Khan, M. N., Fang, W., Zhang, D., & Yao, F. (2023). An 11-year retrospective analysis of candidiasis epidemiology, risk factors, and antifungal susceptibility in a tertiary care hospital in China. Scientific Reports, 13, 5678.

Khan, S.†, Hou, B., Khan, M. N., Shafiq, M., Cai, L.†, Fang, W., Wang, Q., Bilal, H., & Zeng, Y. (2025). A three-year retrospective analysis of microbial species and key biomarkers associated with wound infections in Shantou Hospital, China. Frontiers in Cellular and Infection Microbiology, 15, 15456.

Khan, S., Hameed, M. F., Zafar, I., Bibi, R., Mohany, M., Nazir, S., Kamal, M. A., & Shafiq, M. (2024). Synthesis, characterization, and pharmacological evaluation of Zn4O(BDC)3: Anticancer, antidiabetic, and drug delivery potential. Medicinal Chemistry, 20(3), 145–157.

Varsha Rathore | Cancer Biology | Best Researcher Award

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Dr. Varsha Rathore | Cancer Biology | Best Researcher Award

Department of Pharmacology, College of Medicine, National Taiwan University, Taipei 100233 | Taiwan

Dr. Varsha Rathore’s research focuses on elucidating the molecular mechanisms underlying cancer cell migration, invasion, and survival, with a particular emphasis on the role of CASK (Calcium/Calmodulin-dependent Serine Protein Kinase) in prostate cancer progression. Her doctoral work explores how CASK promotes tumor cell motility and invasiveness independent of TGF-β signaling, contributing to a deeper understanding of tumor metastasis. Additionally, she investigates the involvement of NLRX1 in regulating proliferation, invasion, and survival pathways in prostate cancer cells, offering insights into novel therapeutic targets for cancer treatment. Her expertise spans cell culture, molecular biology, and biochemical assays, including protein expression, purification, ubiquitination, kinase, and PARylation assays, as well as metabolic analysis using Seahorse technology. She has presented her findings at international conferences, including the 19th World Congress of Basic and Clinical Pharmacology and the 38th Joint Academic Conference on Biomedicine. Through her research, Dr. Rathore contributes significantly to the field of molecular oncology and pharmacology, advancing knowledge on how signaling proteins orchestrate cancer progression and identifying potential molecular targets for therapeutic intervention.

Profile: Orcid

Featured Publications:

Rathore, V., Cheng, C.-Y., Lin, C.-Y., Chang, C.-R., & Lin, W.-W. (2025). CASK promotes prostate cancer progression via kinase-dependent activation of AKT. International Journal of Biological Macromolecules, 311(Pt 2), 143965.

Rathore, V., & Lin, W.-W. (2025). Decoding SIGLEC12 in bladder cancer: In silico profiling of expression, tumor–immune interactions, and prognostic impact. Medicina, 61(11), 1894.

Mishra, M., Rathore, V., Sahu, S., & Sahoo, H. (2019). The contribution of nanostructures towards the wing patterning of yellow Catopsilia pomona: How it differs from the lime. Microscopy, 68(4), 289–300.

Wan Wan Lin | Inflammation | Best Researcher Award

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Prof. Wan Wan Lin | Inflammation | Best Researcher Award

Department of Pharmacology, College of Medicine, NTU | Taiwan

Dr. Wan-Wan Lin is a leading researcher in the fields of pharmacology and immunology, with a strong focus on cellular signaling and innate immune mechanisms. Her work has significantly advanced understanding of signal transduction pathways and their regulation of inflammation and cell death. She has made notable contributions to the study of pattern recognition receptors, inflammasomes, and cytokine-mediated immune responses, particularly in the context of oxidative stress and mitochondrial function. Dr. Lin’s research explores how mitochondrial dynamics and redox balance influence inflammatory signaling and programmed cell death, providing key insights into the molecular basis of immune regulation and inflammatory diseases. Her studies have also shed light on the crosstalk between cellular stress responses and immune activation, offering potential therapeutic targets for controlling excessive inflammation and tissue damage. Recognized for her excellence in research, Dr. Lin has received multiple national awards and continues to contribute to the advancement of pharmacological sciences through her editorial and academic roles. Her integrative approach bridges pharmacology, immunology, and cell biology, driving innovations in the understanding of molecular mechanisms underlying inflammation and innate immunity.

Profile: Orcid

Featured Publications:

Lin, W.-W., Lee, C.-Y., Tsai, M.-C., & Tsaur, M.-L. (1985). Pharmacological study on angusticeps-type toxins from mamba snake venoms. Journal of Pharmacology and Experimental Therapeutics, 233, 491–498.

Lin, W.-W., Chang, P.-L., Lee, C.-Y., & Joubert, F. J. (1987). Pharmacological study on phospholipases A₂ isolated from Naja mossambica mossambica venom. Proceedings of the National Science Council, Republic of China B, 11, 155–163.

Lin, W.-W., Lee, C.-Y., & Burnett, J. W. (1988). Effect of sea nettle (Chrysaora quinquecirrha) venom on isolated rat aorta. Toxicon, 26, 1209–1212.

Chiou, S.-H., Lin, W.-W., & Chang, W.-P. (1989). Sequence characterization of venom toxins from Thailand cobra. International Journal of Peptide and Protein Research, 34, 148–152.

Lee, C.-Y., Lin, W.-W., Chen, Y.-M., & Lee, S.-Y. (1989). Is direct cardiotoxicity the primary cause of death following intravenous injection of the basic phospholipase A₂ from Naja nigricollis venom? Acta Physiologica et Pharmacologica Latinoamericana, 39, 383–391.

Lee, C.-Y., & Lin, W.-W. (1989). Two subtypes of acetylcholinesterase isoenzymes distinguishable by Angusticeps-type toxin F7. Comparative Biochemistry and Physiology Part C: Comparative Pharmacology and Toxicology, 92, 279–281.

Lin, W.-W., Lee, C.-Y., & Chuang, D.-M. (1989). Cross-desensitization of endothelin- and sarafotoxin-induced phosphoinositide turnover in neurons. European Journal of Pharmacology, 166, 581–582.

Lin, W.-W., Chen, Y.-M., Lee, S.-Y., Nishio, H., Kimura, T., Sakakibara, S., & Lee, C.-Y. (1990). Cardiovascular effects of two disulfide analogues of sarafotoxin S6b. Toxicon, 28, 911–923.

Lin, W.-W., Lee, C.-Y., Yasumoto, T., & Chuang, D.-M. (1990). Maitotoxin induces phosphoinositide turnover and modulates glutamatergic and muscarinic cholinergic receptor function in cultured cerebellar neurons. Journal of Neurochemistry, 55, 1563–1568.

Lin, W.-W., & Lee, C.-Y. (1990). Biphasic effects of endothelin in the guinea-pig ileum. European Journal of Pharmacology, 176, 57–62.

Shaoqing Ai | Cancer | Best Researcher Award

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Mr. Shaoqing Ai | Cancer | Best Researcher Award

Xi’an Daxing Hospital | China

Dr. Shaoqing Ai’s research focuses on the clinical application and translational potential of integrated traditional Chinese and Western medicine in oncology, particularly in the management of gastrointestinal tumors, lung cancer, and gynecological malignancies. His work emphasizes optimizing multidisciplinary treatment strategies and improving patient outcomes through precision diagnosis and therapy. As an active contributor to the fields of tumor metastasis and geriatric oncology, he has participated in a research project exploring the molecular mechanisms and clinical management of tumor progression and treatment-related complications. His published studies, including one SCI-indexed paper and two Chinese core journal articles, highlight the therapeutic efficacy of combined treatment approaches in reducing radiotherapy- and chemotherapy-induced hematologic toxicities such as leukopenia and thrombocytopenia. Dr. Ai’s research also aims to refine clinical protocols for mitigating adverse effects while enhancing the overall quality of life for cancer patients. Through his involvement in professional oncology committees and collaborative studies, he continues to advance the integration of evidence-based Chinese medicine with modern oncological practices, contributing to the growing body of knowledge supporting individualized and holistic cancer care.

Profile: Orcid

Featured Publications:

Ai, S., Jun, G., Jia, W., & Jie, L. (2025, October 16). Correlation analysis between frequency of gastrointestinal bleeding episodes and abnormal coagulation indexes in digestive system tumors. Scientific Reports. https://doi.org/10.1038/s41598-025-19012-8

 

 

Aakanksha Jain | Neuroimmunology | Best Researcher Award

Published on by Cell Biologist

Dr. Aakanksha Jain | Neuroimmunology | Best Researcher Award

University of Washington | United States

Dr. Aakanksha Jain’s research focuses on elucidating the complex neuroimmune mechanisms underlying pain, inflammation, and autoimmune disorders. Her work integrates immunology and neuroscience to understand how immune and neural cells communicate to regulate pain pathways, with the goal of identifying novel therapeutic targets for chronic inflammatory and autoimmune pain conditions. During her fellowship at Boston Children’s Hospital under the mentorship of Dr. Clifford J. Woolf, she investigated the neuroimmune interactome driving pain sensitization and inflammatory signaling. Her independent research, supported by the NIH K99/R00 HEAL Initiative Award, explores how immune mediators contribute to neural dysfunction and persistent pain in autoimmune arthritis. Dr. Jain’s studies employ advanced molecular, cellular, and imaging approaches to map cross-talk between immune and neuronal networks. She has presented her findings at major conferences, including the Pain Grand Rounds at Johns Hopkins University, the Annual Pain Therapeutics Summit, and the Gordon Conference on Neuroimmune Interactions in Pain. Recognized for her scientific excellence, Dr. Jain’s research contributes to a deeper understanding of immune-neural interactions in disease, paving the way for precision therapies targeting neuroimmune pathways in pain and inflammation.

Profile: Google Scholar

Featured Publications:

Hakim, S., Jain, A., Adamson, S. S., Petrova, V., Indajang, J., Kim, H. W., Kawaguchi, R., Wang, Q., Duran, E. S., Nelson, D., Greene, C., Rasmussen, J., & Woolf, C. J. (2025). Macrophages protect against sensory axon degeneration in diabetic neuropathy. Nature.

Hakim, S., Jain, A., & Woolf, C. J. (2024). Immune drivers of resolution and prevention of pain. Nature Immunology. https://doi.org/10.1038/ni-2024-xxxx (Co-first authors).

Jain, A., Gyori, B., Hakim, S., Sun, L., Petrova, V., Shamsuddin, B. A., Zhen, S., Wang, Q., Kawaguchi, R., Bunga, S., Taub, D. G., Ruiz-Cantero, M. C., Tong-Li, C., Andrews, N., Renthal, W., Sorger, P. K., & Woolf, C. J. (2024). Nociceptor-immune interactomes reveal insult-specific immune signatures of pain. Nature Immunology.

Jain, A., Hakim, S., & Woolf, C. J. (2024). Immune drivers of physiological and pathological pain. Journal of Experimental Medicine. (Co-first authors).

McDaniel, M. M., Singh, A. S., Jain, A.*, Meibers, H. E., Sara, I., Gao, Y., Jain, V., Roskin, K., Way, S. S., & Pasare, C. (2022). Effector memory CD4⁺ T cells induce damaging innate inflammation and autoimmune pathology by engaging CD40 and TNFR on myeloid cells. Science Immunology. (Co-first authors).

Ruiz-Cantero, M. C., Cortés-Montero, E., Jain, A., Montilla-García, A., Bravo-Caparrós, I., Shim, J., Sánchez-Blázquez, P., Woolf, C. J., Baeyens, J. M., & Cobos, E. J. (2022). The sigma-1 receptor curtails endogenous opioid analgesia during sensitization of TRPV1 nociceptors. British Journal of Pharmacology.

Jain, A., Hakim, S., & Woolf, C. J. (2020). Unraveling the plastic peripheral neuroimmune interactome. Journal of Immunology, 204(2), 257–263.

Jain, A., Irizarry-Caro, R. A., McDaniel, M. M., Chawla, A. S., Philip, N. H., Carroll, K. R., Overcast, G. O., Katz, J., Oberst, A., Chervonsky, A., & Pasare, C. (2019). T cells instruct myeloid cells to produce inflammasome-independent IL-1β and cause autoimmunity. Nature Immunology, 21(1), 65–74.

Lee, S., Talbot, S., Jo, S., Zhang, H. B., Kotoda, M., Andrews, N., Heckman, L. M., Puopolo, M., Liu, P., Jain, A., Jacquemont, T., Lee, J., Woolf, C., & Bean, B. P. (2019). A novel charged sodium and calcium channel inhibitor active against neurogenic inflammation. eLife, 8, e12345.

Stefan Oliver | Cryogenic Electron Tomography | Best Researcher Award

Published on by Cell Biologist

Dr. Stefan Oliver | Cryogenic Electron Tomography | Best Researcher Award

SLAC National Accelerator Laboratory | United States

Dr. Stefan L. Oliver is a leading virologist and structural biologist whose research focuses on understanding virus–host interactions and the structural organization of viral complexes within infected cells. As Lead Scientist at the SLAC National Accelerator Laboratory, Stanford University, he directs laboratory operations and research programs centered on the tomographic reconstruction and segmentation of macromolecular assemblies in situ, particularly investigating the varicella-zoster virus (VZV) using advanced cryo-focused ion beam/scanning electron microscopy (cryoFIB/SEM) and cryo-electron tomography (cryo-ET). His work integrates cutting-edge imaging technologies with molecular virology to elucidate the ultrastructural mechanisms of viral infection, replication, and pathogenesis. At the Stanford University School of Medicine, Dr. Oliver’s research advances the understanding of viral morphogenesis and host cell remodeling during infection, contributing to the broader field of structural virology. His studies provide critical insights into how viral particles assemble and interact with cellular machinery at the nanoscale level. In addition to his research, Dr. Oliver serves as an Associate Editor for Frontiers in Microbiology – Virology and has guest-edited a special issue of Viruses on “Virus-Induced Syncytia,” highlighting his active role in advancing scholarly communication within the virology research community.

Profiles: Google Scholar | Orcid

Featured Publications:

Oliver, S. L., Chen, M., Engel, L., Hecksel, C. W., Zhou, X., Schmid, M. F., Arvin, A. M., & Chiu, W. (2025). Cryogenic electron tomography redefines herpesvirus capsid assembly intermediates inside the cell nucleus. bioRxiv. https://doi.org/10.1101/2025.06.27.661840

Engel, L., Zaoralova, Z., Dunn, A. R., & Oliver, S. L. (2025). Extracellular filaments revealed by affinity capture cryoelectron tomography of lymphocytes. Nature Communications, 16, 9802. https://doi.org/10.1038/s41467-025-64795-z

Zhou, M., Vollmer, B., Machala, E., Chen, M., Grünewald, K., Arvin, A. M., Chiu, W., & Oliver, S. L. (2023). Targeted mutagenesis of the herpesvirus fusogen central helix captures transition states. Nature Communications, 14(1), 7958. https://doi.org/10.1038/s41467-023-43011-w

Alexander, L. T., Lepore, R., Kryshtafovych, A., et al. (2021). Target highlights in CASP14: Analysis of models by structure providers. Proteins: Structure, Function, and Bioinformatics. https://doi.org/10.1002/prot.26247

Oliver, S. L., Xing, Y., Chen, D. H., Roh, S. H., Pintilie, G. D., Bushnell, D. A., Sommer, M. H., Yang, E., Carfi, A., Chiu, W., & Arvin, A. M. (2021). The N-terminus of varicella-zoster virus glycoprotein B has a functional role in fusion. PLoS Pathogens, 17(3), e1008961. https://doi.org/10.1371/journal.ppat.1008961

Zhou, M., Kamarshi, V., Arvin, A. M., & Oliver, S. L. (2020). Calcineurin phosphatase activity regulates varicella-zoster virus-induced cell-cell fusion. PLoS Pathogens, 16(11), e1009022. https://doi.org/10.1371/journal.ppat.1009022

Oliver, S. L., Xing, Y., Chen, D., Roh, S. H., Pintilie, G. D., Bushnell, D. A., Sommer, M. H., Yang, E., Carfi, A., Chiu, W., & Arvin, A. M. (2020). A glycoprotein B-neutralizing antibody structure at 2.8Å uncovers a critical domain for herpesvirus fusion initiation. Nature Communications, 11(1), 4141. https://doi.org/10.1038/s41467-020-17911-0

Yang, E., Gardner, M. R., Zhou, A. S., Farzan, M., Arvin, A. M., & Oliver, S. L. (2018). HIV-1 inhibitory properties of eCD4-Igmim2 determined using an Env-mediated membrane fusion assay. PLoS ONE, 13(10), e0206365. https://doi.org/10.1371/journal.pone.0206365

Yang, E., Arvin, A. M., & Oliver, S. L. (2017). The glycoprotein B cytoplasmic domain lysine cluster is critical for varicella-zoster virus cell-cell fusion regulation and infection. Journal of Virology, 91(4), e01707-16. https://doi.org/10.1128/JVI.01707-16

Waldemar Debinski | Cancer Cell Biology | Best Researcher Award

Published on by Cell Biologist

Prof. Dr. Waldemar Debinski | Cancer Cell Biology | Best Researcher Award

Wake Forest School of Medicine | United States

Dr. Waldemar Debinski, M.D., Ph.D., is a distinguished neuroscientist and cancer researcher recognized for his pioneering work in brain tumor biology and targeted molecular therapies. His research focuses on understanding the molecular mechanisms that drive the development and progression of malignant brain tumors, with a particular emphasis on gliomas. Dr. Debinski has significantly contributed to the development of novel targeted therapeutics, including receptor-directed cytotoxins and biologics designed to selectively eliminate tumor cells while sparing healthy tissues. His investigations bridge molecular oncology, translational science, and clinical application, aiming to improve therapeutic outcomes for patients with brain cancers. Throughout his career, he has integrated insights from physiology, molecular biology, and pharmacology to develop translational approaches that move from laboratory discovery to clinical implementation. His extensive research has advanced the understanding of tumor-specific receptors and intracellular signaling pathways, contributing to innovative strategies in cancer immunotherapy and precision medicine. Dr. Debinski’s work exemplifies the integration of basic and clinical research toward the development of next-generation treatments for central nervous system malignancies, positioning him as a leading figure in neuro-oncology and translational cancer research.

Profile: Scopus

Featured Publications:

Wocial, B., Januszewicz, W., Siedlecki, J., Feltynowski, T., & Debinski, W. (1982). Alterations in plasma dopamine-β-hydroxylase and catecholamine concentrations during surgical removal of pheochromocytoma. Endocrinologie, 79, 131–139.

Debinski, W., & Wocial, B. (1982). Various aspects of sodium metabolism in hypertension [in Polish]. Polski Tygodnik Lekarski, 37, 1339–1342.

Ignatowska-Świtalska, H., Debinski, W., & Chojnowski, K. (1983). The role of certain hormonal factors in arterial hypertension [in Polish]. Materia Medica Polona, 15, 74–86.

Wasawska, T., Feltynowski, T., Majewska, Z., Januszewicz, W., Sobolewska-Karwowska, A., Wocial, B., & Debinski, W. (1984). Pheochromocytoma: Description of two cases with an unusual clinical picture [in Polish]. Polski Tygodnik Lekarski, 39, 261–263.

Czarkowski, M., & Debinski, W. (1984). Sodium and primary arterial hypertension [in Polish] (Review). Kardiologia Polska, 27, 967–976.

Wocial, B., Debinski, W., Jablonska-Skwicinska, E., Feltynowski, T., Chodakowska, J., Kozakowska, E., & Januszewicz, W. (1984). Sodium content of erythrocytes in patients with arterial hypertension [in Polish]. Polski Archiwum Medycyny Wewnetrznej, 72, 167–174.

Garcia, R., Debinski, W., Gutkowska, J., Kuchel, O., Thibault, G., Genest, J., & Cantin, M. (1985). Gluco- and mineralocorticoids may regulate the natriuretic effect and the synthesis and release of atrial natriuretic factor by the rat atria in vivo. Biochemical and Biophysical Research Communications, 131, 806–814.

Debinski, W., Kuchel, O., Garcia, R., Buu, N. T., Racz, K., Cantin, M., & Genest, J. (1986). Atrial natriuretic factor inhibits sympathetic activity in one-kidney, one-clip hypertension in the rat. Proceedings of the Society for Experimental Biology and Medicine, 181, 173–177.

Debinski, W., Kuchel, O., Buu, N. T., Garcia, R., Cantin, M., & Genest, J. (1986). Involvement of the adrenal glands in the action of the atrial natriuretic factor. Proceedings of the Society for Experimental Biology and Medicine, 181, 318–324.

Debinski, W., Gutkowska, J., Kuchel, O., Racz, K., Buu, N. T., Cantin, M., & Genest, J. (1986). ANF-like peptide(s) in the peripheral autonomic nervous system. Biochemical and Biophysical Research Communications, 134, 279–284.

Elena Pradedova | Redox Systems of the Plant Cell Vacuole | Best Researcher Award

Published on by Cell Biologist

Dr. Elena Pradedova | Redox Systems of the Plant Cell Vacuole | Best Researcher Award

Siberian Institute of Plant Physiology and Biochemistry, Siberian Branch, Russian Academy of Sciences | Russia

Dr. Elena Vladimirovna Pradedova is a distinguished plant physiologist and biochemist whose research has significantly advanced the understanding of vacuolar function in plant cells. Her pioneering studies revealed that the plant cell vacuole, previously considered a passive compartment, plays an active and crucial role in cellular defense mechanisms against biotic and abiotic stressors. She conducted the first comprehensive investigation into vacuolar antioxidant enzymes, identifying and characterizing the activities of superoxide dismutase, ascorbate oxidase, and alcohol dehydrogenase within the vacuole. Her work also led to the first determination of the vacuolar redox potential, offering vital insights into intracellular redox homeostasis. Focusing on proton pumps, active sugar transport across the vacuolar membrane, and the vacuole’s redox systems, her research bridges molecular, biochemical, and physiological approaches to elucidate plant stress responses. Through her publications in respected journals such as Plant Physiology and Biochemistry, Biochemistry (Moscow), and the Russian Journal of Plant Physiology, she has contributed valuable knowledge on reactive oxygen species generation, antioxidant defense mechanisms, and detoxification pathways in plant cells. Her findings highlight the vacuole’s essential protective and regulatory roles, transforming the conceptual understanding of plant cell biology and its adaptive responses to environmental challenges.

Profiles: Google Scholar | Scopus

Featured Publications:

Pradedova, E. V. (2021). Redox systems of the plant cell vacuole compared to redox systems of other subcellular structures. [Review].

Pradedova, E. V. (2021). Redox systems of the plant cell vacuole. [Review].

Pradedova, E. V. (2021, Conference paper). Effects of biotic factor on antioxidant defense system of vacuoles of red beetroot cells. [Conference presentation, Open Access].

Pradedova, E. V. (2021). Glutathione system is a detoxification mechanism of herbicides in vacuoles and plastids of red beetroot cells. Siberian Journal of Life Sciences and Agriculture. [Open Access].