Alaka Sahoo | Immunology Cellular Interactions | Young Researcher Award

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Mrs. Alaka Sahoo | Immunology Cellular Interactions | Young Researcher Award

Mrs. Alaka Sahoo, Siksha’O’ Anusandhan University, India

Dr. Alaka Sahoo is a dedicated young researcher in the field of Biotechnology with a focus on translational and clinical research. She holds a Ph.D. in Biotechnology from Siksha ‘O’ Anusandhan University, Odisha, with a CGPA of 8.90. With over 17 publications, including 11 research articles and 3 high-impact reviews, Dr. Sahoo has significantly contributed to oral disease therapeutics and antimicrobial studies. She demonstrates expertise in multi-omics analysis, drug discovery, and natural product-based therapy. A recipient of prestigious awards such as the Lalchand Women Entrepreneurs Award (2024), she is also a life member of reputed organizations like the British Society for Antimicrobial Chemotherapy. Her innovative approach to disease management using phytochemicals and peptides sets her apart as a rising talent in biomedical research.

Publication Profile: 

Google Scholar

Scopus

Orcid

✅ Strengths for the Award:

  1. Strong Publication Record:

    • 17 publications including 11 original research, 3 reviews, and 2 book chapters, showcasing depth and breadth.

    • 7 papers as first or corresponding author—indicating independent research capability.

    • Research in high-impact journals like Frontiers in Microbiology, Journal of Ethnopharmacology, Nanomaterials, and Chemistry & Biodiversity.

  2. Innovative & Multidisciplinary Research:

    • Integrates multi-omics, computational modeling, clinical dermatology, and natural products.

    • Focus on oral inflammatory diseases, antimicrobial peptides, and drug delivery systems.

  3. Academic Excellence & Research Training:

    • Ph.D. with 8.90 CGPA, and M.Sc. with 87.07% marks.

    • Expertise in BSL-2+ lab work, PCR, ELISA, microbial culture, and molecular docking.

  4. Awards & Recognition:

    • Lalchand Women Entrepreneurs Award (2024).

    • MSME-Idea Hackathon Innovation Award, Govt. of India.

  5. Global and National Engagement:

    • Life member of the British Society for Antimicrobial Chemotherapy (UK).

    • Demonstrates leadership in science entrepreneurship and women in research.

🛠️ Areas for Improvement:

  1. Expanded International Collaboration:

    • Building long-term research partnerships with international labs could increase global visibility.

  2. Patent/Technology Transfer Efforts:

    • While publications are strong, translating research into patents or commercial products will further strengthen applied impact.

  3. Focused Project Leadership:

    • Leading large interdisciplinary projects or acquiring independent grants will showcase funding leadership.

🎓 Education:

Dr. Alaka Sahoo has pursued a progressive academic path in Biotechnology. She earned her Ph.D. in Biotechnology from the School of Pharmaceutical Sciences, Siksha ‘O’ Anusandhan Deemed University, Odisha, completing her research with a notable 8.90 CGPA. Her thesis focused on “Therapeutic Opportunities for Oral Lichen Planus: An Integrated Multi-Omics Approach to Drug Discovery” under the guidance of Prof. (Dr.) Maitreyee Panda. Prior to this, she completed her M.Sc. in Biotechnology (87.07%) from the College of Basic Science and Humanities, OUAT, Bhubaneswar in 2018 and a B.Sc. in Biotechnology with distinction (75%) from Ramadevi Women’s College, Utkal University in 2016. Her academic journey showcases a strong foundation in both theoretical and applied aspects of biosciences.

💼 Experience:

Dr. Alaka Sahoo brings rich hands-on research experience in clinical and experimental biotechnology. She is skilled in BSL-2+ lab practices, molecular techniques like PCR, gel electrophoresis, microbial culture, ELISA-based diagnostics, and bioinformatics. Her doctoral work integrated multi-omics and computational biology to study inflammatory oral diseases, and her postdoctoral research spans drug delivery and antimicrobial drug discovery. As first or corresponding author in 7 out of 17 publications, she has led collaborative studies with both national and international partners. Dr. Sahoo’s cross-disciplinary knowledge in microbiology, pharmacology, and nanomedicine enhances her problem-solving abilities, making her a versatile researcher. Her ability to bridge clinical dermatology with biotechnology research positions her as an impactful contributor in both healthcare and academic environments.

🏆 Awards & Honors:

Dr. Alaka Sahoo has received notable accolades for her innovation and leadership in science. In 2024, she was awarded the Lalchand Women Entrepreneurs Award by the Odisha Corporate Foundation, recognizing her outstanding contributions in biotech innovation. She also earned the MSME-Idea Hackathon 3.0 (Women) Innovation Award by the Government of India, honoring her practical scientific advancements with societal impact. These awards reflect her dedication to translational research and her vision to develop cost-effective, natural therapies. Dr. Sahoo is also a life member of two esteemed organizations: the British Society for Antimicrobial Chemotherapy (UK) and Bioclues Innovation, Research and Development (India). Her achievements signify her rising prominence in the field and her commitment to addressing public health challenges through integrative research.

🔬 Research Focus:

Dr. Alaka Sahoo’s research focuses on oral inflammatory diseases, natural product therapeutics, and insect-derived peptides as alternatives to conventional antimicrobials. Her Ph.D. thesis explored multi-omics approaches for drug discovery in Oral Lichen Planus, integrating in vitro, in silico, and clinical data. Her work spans immunomodulation, anti-inflammatory drug screening, and nanodrug delivery systems, with cross-functional expertise in dermatology, pharmacology, and microbiology. She combines computational modeling, molecular docking, and wet-lab validation to develop target-specific therapies. Her studies on biofilm inhibition, antifungal peptides, and phytosteroids hold promise for tackling antimicrobial resistance. Through collaborations across academia and healthcare, she aims to translate her lab findings into clinically viable solutions. Her contributions to systematic reviews and molecular simulations further demonstrate her analytical rigor and commitment to evidence-based research.

📚 Publications Top Notes:

  1. 📘 Experimental and clinical trial investigations of phytoextracts in Oral Lichen Planus: A systematic review – J Ethnopharmacol (2022)

  2. 🐞 Insect-derived antimicrobial peptides as novel anti-biofilm agents: A systematic review – Front. Microbiol. (2021)

  3. 💊 Ultraflexible liposome nanocargo for dermal drug delivery – Nanomaterials (2021)

  4. 🌿 Phytochemicals for Oral Lichen Planus: A multi-omics and experimental study – Chem Biodivers (2025)

  5. ⚗️ Carbohydrate-derived N-benzyl aminocyclopentitols with anticancer properties – Carbohydr Res. (2025)

  6. 🧬 Target-specific screening of anti-inflammatory phytosteroids using molecular docking – Steroids (2025)

  7. 🧪 Insect-derived antifungal peptides in Candida management – Int. J. Mol. Sci. (2025)

  8. 🧫 Azo-coumarin-Co(II)-galangin hybrids for multipotential activities – J. Biomol. Struct. Dyn. (2024)

  9. 🧒 Pediatric dermatology case analysis in Eastern India – Indian J. Paediatr. Dermatol. (2024)

  10. 🔬 Schiff/Mannich coumarin derivatives: Antibacterial and anti-biofilm evaluation – RSC Adv. (2024)

🧾 Conclusion:

Dr. Alaka Sahoo is highly suitable for the Research for Young Researcher Award. Her multi-disciplinary expertise, robust research record, and recognition through national awards highlight her as a promising early-career scientist. She combines academic rigor with innovation, and her work has meaningful implications for public health, especially in oral disease therapy, biofilm inhibition, and phytochemical-based drug development.

Herbeuval Jean-Philippe | Immunology Cellular Interactions | Best Innovator Award

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Dr. Herbeuval Jean-Philippe | Immunology Cellular Interactions | Best Innovator Award

Dr. Herbeuval Jean-Philippe | CNRS | France

Jean-Philippe Herbeuval is a French immunologist and CNRS Director of Research, renowned for pioneering contributions to translational immunology and biomedical innovation. A PhD holder in immuno-oncology, he completed a prestigious Fogarty Fellowship at the NIH, USA, where he earned the Norman P. Salzman Award. He founded and leads the CBMIT team at Université Paris Cité, integrating immunology, virology, and chemistry for therapeutic discovery. Herbeuval has launched two biotech companies: Ermium Therapeutics, based on anti-interferon therapies, and Elyris Pharma, centered on PDK1 as a novel anti-inflammatory target. With 9 patents (3 licensed), €8.8M in research funding, and >70 publications (h-index 28), his innovations span diagnostics to therapeutics. He also contributes to policy and innovation strategy through national and international committees. Recognized for his vision, leadership, and mentorship, Herbeuval exemplifies the intersection of academic research and impactful biotechnology entrepreneurship.

Publication Profile:

Google Scholar

✅ Strengths for the Award:

  1. Exceptional Innovation in Immunology & Therapeutics

    • Discovered key therapeutic targets such as CXCR4 and PDK1.

    • Founded Ermium Therapeutics (2019) and Elyris Pharma (2024), securing over €12M in funding.

    • Holds 9 patents, with 3 already licensed — a key indicator of translational success.

  2. Proven Scientific Leadership

    • Director of Research (CNRS), Head of CBMIT at Université Paris Cité.

    • Established and led multiple interdisciplinary research teams and platforms (Cyto2BM, CBMIT).

    • Supervised 10 PhD students, 7 postdocs, and over 18 master’s students, many of whom reached elite positions.

  3. High-Impact Research Output

    • 70+ publications, including high-citation studies on interferon signaling in HIV.

    • Over 3,500 citations, h-index: 28 — showing strong impact and visibility.

  4. Strong National and International Recognition

    • Winner of the prestigious i-Lab National Innovation Prize (France, 2019).

    • Invited speaker at over 24 international conferences; reviewer for Nature Medicine and PNAS.

    • Advisor for funding agencies across the US (NIH), UK (MRC), China, and Brazil.

  5. Valuable Public and Government Engagement

    • CNRS Innovation Ambassador (2024) and expert for multiple national programs (ANRS, Campus France).

    • Actively engages in public science communication (TV, radio, press).

🔧 Areas for Improvement:

  1. Scaling Global Industry Impact

    • While Ermium and Elyris are high-potential, further proof of market adoption and therapeutic success will solidify his innovation leadership globally.

  2. Broader Patent Commercialization

    • More patents could potentially be moved from licensing to full-scale clinical trials or product development phases.

  3. Diversity of Therapeutic Areas

    • While the focus on interferon biology and immunomodulation is powerful, broader expansion into other disease domains (e.g., neuroinflammation, metabolic syndromes) could enhance reach.

🎓 Education:

Jean-Philippe Herbeuval earned his PhD in immuno-oncology in 2001 from Université Jean Monnet, Saint-Étienne, working under the INSERM network. He then pursued a highly competitive five-year Fogarty Postdoctoral Fellowship at the National Institutes of Health (NIH), USA, under Dr. Gene Shearer, focusing on the antiviral response to HIV. During this time, he earned multiple prestigious awards including the Norman P. Salzman Award and an NIH Young Scientist Cash Award. Upon returning to France, he secured a CNRS Junior PI position in 2006 and received his Habilitation to Direct Research (HDR) in 2008 from Université Paris Descartes. His rapid career progression continued with his appointment as Director of Research (2nd class) in 2013 and promotion to 1st class in 2019 at CNRS UMR8601. His educational path reflects an exceptional blend of scientific rigor, international exposure, and leadership in innovation.

💼 Experience:

Jean-Philippe Herbeuval brings over two decades of distinguished experience at the interface of academic research and biotech innovation. Starting with his postdoctoral fellowship at NIH (2001–2006), he led groundbreaking studies on interferon responses in HIV. Since 2006, he has served within CNRS, creating and leading the CBMIT interdisciplinary team. He established the Cyto2BM core facility and spearheaded multiple translational projects. As scientific founder of Ermium Therapeutics (2019) and Elyris Pharma (2024, in progress), he has successfully attracted venture capital and secured technology transfer agreements. His strategic involvement extends to national innovation committees (ANRS, CNRS, Campus France) and advisory roles. He has trained over 35 researchers and supervised major national/international grants. Notably, he combines deep scientific insight with an entrepreneurial mindset, as shown by his participation in Deeptech Founders and RISE programs. His experience spans leadership, translational science, investment negotiations, and scientific mentoring.

🔬 Research Focus:

Jean-Philippe Herbeuval’s research is centered on translational immunology, particularly type I interferons, autoinflammatory pathways, and host-pathogen interactions. His work explores immune dysregulation in infectious diseases such as HIV, SARS-CoV-2, dengue, and influenza, with a special focus on the immune-modulatory roles of dendritic cells and apoptotic pathways. He has identified novel therapeutic targets including CXCR4 and PDK1, leading to two biotech start-ups and multiple patents. His interdisciplinary CBMIT team integrates immunology, virology, medicinal chemistry, and computational modeling to develop innovative therapeutic strategies and biomarkers. He has a keen interest in immunomodulation, therapeutic interference with IFN pathways, and discovery of druggable checkpoints in innate immunity. With over 70 peer-reviewed publications, his scientific output has shaped current understanding of immune pathogenesis and opened new avenues for therapy in inflammatory and infectious diseases. His approach bridges fundamental research with practical applications in drug discovery and biotech development.

📚 Publications Top Notes:

  1. 🧬 HIV inhibits CD4+ T-cell proliferation by inducing indoleamine 2,3-dioxygenase in plasmacytoid dendritic cells

  2. ⚰️ CD4+ T-cell death induced by infectious and noninfectious HIV-1: role of type 1 interferon–dependent, TRAIL/DR5-mediated apoptosis

  3. 🚻 Sex differences in plasmacytoid dendritic cell levels of IRF5 drive higher IFN-α production in women

  4. 🧪 HIV-1 immunopathogenesis: how good interferon turns bad

  5. 🔄 Regulation of indoleamine 2,3-dioxygenase and tryptophanyl-tRNA-synthetase by CTLA-4-Fc in human CD4+ T cells

  6. 🧠 Differential expression of IFN-α and TRAIL/DR5 in lymphoid tissue of progressor vs. nonprogressor HIV-1-infected patients

  7. 🧟 HIV turns plasmacytoid dendritic cells into TRAIL-expressing killer pDC via TLR7-induced IFN-α

  8. 🧬 Regulation of TRAIL on primary CD4+ T cells by HIV-1: role of plasmacytoid dendritic cells

  9. 💉 TRAIL in HIV-1–infected patients and its production by antigen-presenting cells

  10. 🧫 Recruitment of STAT3 for production of IL-10 by colon carcinoma cells induced by macrophage-derived IL-6

🧾 Conclusion:

Dr. Jean-Philippe Herbeuval stands out as a highly qualified and deserving candidate for the Best Innovator Award. His rare combination of scientific excellence, translational innovation, entrepreneurial leadership, and mentorship places him in the top tier of biomedical innovators. His work not only bridges science and industry but also directly contributes to addressing global health challenges. Continued support and recognition of his efforts will likely catalyze further innovation in therapeutic immunology.

Zhi Guo | Stem Cell Research | Best Researcher Award

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Prof. Dr Zhi Guo | Stem Cell Research | Best Researcher Award

Prof. Dr Zhi Guo | Department of Hematology, Huazhong University of Science and Technology Union Shenzhen Hospital | China

Dr. Zhi Guo is a distinguished expert in hematology with over 25 years of clinical and academic experience. Currently serving as Director, Academic Leader, Chief Physician, and Professor at the Department of Hematology, Huazhong University of Science and Technology Union Shenzhen Hospital, he has been instrumental in advancing hematologic malignancy treatments in China. With extensive expertise in hematopoietic stem cell transplantation, Dr. Guo has successfully performed more than 1,300 transplant cases. He began his career at the PLA Army General Hospital, serving there for nearly two decades before transitioning to his current role. A prolific researcher, he has authored over 10 peer-reviewed publications and five books, contributing substantially to the understanding of CAR-T therapy, gut microbiota, and transplantation immunology. He is an active member of major national and international hematology associations and plays a vital role in formulating clinical consensus and guidelines in China.

publication profile:

Scopus

Strengths for the Award:

Dr. Zhi Guo exemplifies the qualities of an outstanding medical researcher and clinician. With nearly 25 years of clinical experience in hematology and over 20 years in hematopoietic stem cell transplantation, he stands out as a national leader in this field. His performance of more than 1,300 transplants, along with a strong academic footprint, including 10 SCI-indexed publications in 2024–2025, demonstrates both depth and innovation in his research. He has also contributed to national expert consensus and clinical guidelines, particularly in CAR-T therapy and intestinal microecology. Dr. Guo’s leadership roles across national academic committees and his active membership in the American Society of Hematology further highlight his international impact and collaborative influence.

Areas for Improvement:

While Dr. Guo’s achievements in clinical practice and research are significant, opportunities exist to increase global visibility by expanding his research collaborations internationally and publishing in higher-impact journals beyond regional scopes. Additionally, while five books have been authored, the addition of patents or translational innovations could enhance his profile in the realm of research commercialization and practical medical technologies.

Education :

Dr. Zhi Guo holds a strong academic background in clinical medicine and medical research. He earned his Bachelor’s degree in Medicine from Tongji Medical College in 2000. Subsequently, he pursued his postgraduate medical studies at the Third Military Medical University, completing it in 2007. His academic journey culminated with the attainment of a Doctor of Medicine (MD) degree from Wuhan University of Science and Technology. His education laid a strong foundation in hematology and clinical research methodologies. Each step in his educational path was marked by an emphasis on academic rigor and clinical competence, preparing him for a leadership role in medical science and hematologic research. His multidisciplinary background has enabled him to integrate clinical insights with advanced laboratory-based innovations, contributing to national-level guidelines and the development of cutting-edge CAR-T cell therapies and transplantation techniques.

Experience :

Dr. Zhi Guo brings nearly 25 years of clinical, academic, and leadership experience in the field of hematology. He began his professional journey at the PLA Army General Hospital, where he served from 2000 to 2018. During this period, he honed his clinical and procedural expertise in managing complex hematologic disorders. Since 2018, he has been leading the Department of Hematology at Huazhong University of Science and Technology Union Shenzhen Hospital as Director, Academic Leader, and Chief Physician. His rich experience includes more than 1,300 hematopoietic stem cell transplantations, encompassing autologous, allogeneic, and CAR-T integrated therapies. His leadership extends beyond clinical care, as he also mentors postgraduate medical students and leads multiple national and institutional research projects. Dr. Guo’s practical experience is balanced with his strategic contributions to medical consensus formulation and research-driven policy initiatives in cancer and immune-hematological disorders.

Research Focus :

Dr. Zhi Guo’s research centers on hematologic malignancies and hematopoietic stem cell transplantation, particularly the integration of cellular immunotherapy such as CAR-T cell treatments. His recent work includes pioneering anti-CD19, anti-CD7, and anti-BCMA CAR-T therapies for lymphomas and leukemias. Additionally, he has investigated the interplay between microbiota and immune modulation in transplantation, highlighting the role of gut and oral microbiomes in patient outcomes. His contributions have influenced the development of clinical guidelines for microbiota-related diagnostics and treatments in oncology. With more than 10 high-impact journal publications and ongoing projects in translational medicine, Dr. Guo’s work combines laboratory innovation with patient-centered applications. He has also authored expert consensus documents and national guidelines, helping shape China’s hematology and transplantation protocols. His commitment to interdisciplinary collaboration, clinical innovation, and translational research underscores his leading role in advancing modern hematology.

Publications Top Notes:

  1. 🧬 In vitro validation of anti-CD19 CAR-T cells with LSD1 shRNA for DLBCL – Front Immunol, 2025

  2. 🩸 Case of T-ALL treated with chemo + anti-CD7 CAR-T (retroviral vector) – Front Immunol, 2025

  3. 👶 Shaping oral/intestinal microbiota & immunity in first 1,000 days of life – Front Pediatr, 2025

  4. 💩 Fecal microbiota transplantation in acute GVHD treatment – J Cancer Res Ther, 2024

  5. 🔬 Chinese consensus on gut microecology lab standards – Exp Ther Med, 2024

  6. 🧪 2024 Chinese guidelines for intestinal microecology in cancer – J Cancer Res Ther, 2024

  7. 🧫 First MM case treated with ASCT + anti-BCMA CAR-T (retrovirus) – Heliyon, 2024

  8. 🧾 Rapid response in relapsed FL to anti-CD19 CAR-T with CMV – Int Immunopharmacol, 2024

  9. 🦷 Prognostic impact of oral microbiome in cancer survival – meta-analysis – Syst Rev, 2024

  10. 🧍‍⚕️ Expert consensus on gut microbiome & hematopoietic stem cell transplantation – Clin Transplant, 2024

Conclusion:

In conclusion, Dr. Zhi Guo is highly suitable for the Best Researcher Award. His combination of clinical excellence, academic leadership, and impactful research in hematology and stem cell transplantation positions him among the top contributors in this specialized field. With ongoing research in CAR-T cell therapies, microbiota influence on transplantation, and immuno-oncology, Dr. Guo continues to shape the future of hematologic cancer care. Recognizing his contributions with this award would be both fitting and encouraging for continued innovation in this vital area of medicine.