Herbeuval Jean-Philippe | Immunology Cellular Interactions | Best Innovator Award

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Dr. Herbeuval Jean-Philippe | Immunology Cellular Interactions | Best Innovator Award

Dr. Herbeuval Jean-Philippe | CNRS | France

Jean-Philippe Herbeuval is a French immunologist and CNRS Director of Research, renowned for pioneering contributions to translational immunology and biomedical innovation. A PhD holder in immuno-oncology, he completed a prestigious Fogarty Fellowship at the NIH, USA, where he earned the Norman P. Salzman Award. He founded and leads the CBMIT team at Université Paris Cité, integrating immunology, virology, and chemistry for therapeutic discovery. Herbeuval has launched two biotech companies: Ermium Therapeutics, based on anti-interferon therapies, and Elyris Pharma, centered on PDK1 as a novel anti-inflammatory target. With 9 patents (3 licensed), €8.8M in research funding, and >70 publications (h-index 28), his innovations span diagnostics to therapeutics. He also contributes to policy and innovation strategy through national and international committees. Recognized for his vision, leadership, and mentorship, Herbeuval exemplifies the intersection of academic research and impactful biotechnology entrepreneurship.

Publication Profile:

Google Scholar

✅ Strengths for the Award:

  1. Exceptional Innovation in Immunology & Therapeutics

    • Discovered key therapeutic targets such as CXCR4 and PDK1.

    • Founded Ermium Therapeutics (2019) and Elyris Pharma (2024), securing over €12M in funding.

    • Holds 9 patents, with 3 already licensed — a key indicator of translational success.

  2. Proven Scientific Leadership

    • Director of Research (CNRS), Head of CBMIT at Université Paris Cité.

    • Established and led multiple interdisciplinary research teams and platforms (Cyto2BM, CBMIT).

    • Supervised 10 PhD students, 7 postdocs, and over 18 master’s students, many of whom reached elite positions.

  3. High-Impact Research Output

    • 70+ publications, including high-citation studies on interferon signaling in HIV.

    • Over 3,500 citations, h-index: 28 — showing strong impact and visibility.

  4. Strong National and International Recognition

    • Winner of the prestigious i-Lab National Innovation Prize (France, 2019).

    • Invited speaker at over 24 international conferences; reviewer for Nature Medicine and PNAS.

    • Advisor for funding agencies across the US (NIH), UK (MRC), China, and Brazil.

  5. Valuable Public and Government Engagement

    • CNRS Innovation Ambassador (2024) and expert for multiple national programs (ANRS, Campus France).

    • Actively engages in public science communication (TV, radio, press).

🔧 Areas for Improvement:

  1. Scaling Global Industry Impact

    • While Ermium and Elyris are high-potential, further proof of market adoption and therapeutic success will solidify his innovation leadership globally.

  2. Broader Patent Commercialization

    • More patents could potentially be moved from licensing to full-scale clinical trials or product development phases.

  3. Diversity of Therapeutic Areas

    • While the focus on interferon biology and immunomodulation is powerful, broader expansion into other disease domains (e.g., neuroinflammation, metabolic syndromes) could enhance reach.

🎓 Education:

Jean-Philippe Herbeuval earned his PhD in immuno-oncology in 2001 from Université Jean Monnet, Saint-Étienne, working under the INSERM network. He then pursued a highly competitive five-year Fogarty Postdoctoral Fellowship at the National Institutes of Health (NIH), USA, under Dr. Gene Shearer, focusing on the antiviral response to HIV. During this time, he earned multiple prestigious awards including the Norman P. Salzman Award and an NIH Young Scientist Cash Award. Upon returning to France, he secured a CNRS Junior PI position in 2006 and received his Habilitation to Direct Research (HDR) in 2008 from Université Paris Descartes. His rapid career progression continued with his appointment as Director of Research (2nd class) in 2013 and promotion to 1st class in 2019 at CNRS UMR8601. His educational path reflects an exceptional blend of scientific rigor, international exposure, and leadership in innovation.

💼 Experience:

Jean-Philippe Herbeuval brings over two decades of distinguished experience at the interface of academic research and biotech innovation. Starting with his postdoctoral fellowship at NIH (2001–2006), he led groundbreaking studies on interferon responses in HIV. Since 2006, he has served within CNRS, creating and leading the CBMIT interdisciplinary team. He established the Cyto2BM core facility and spearheaded multiple translational projects. As scientific founder of Ermium Therapeutics (2019) and Elyris Pharma (2024, in progress), he has successfully attracted venture capital and secured technology transfer agreements. His strategic involvement extends to national innovation committees (ANRS, CNRS, Campus France) and advisory roles. He has trained over 35 researchers and supervised major national/international grants. Notably, he combines deep scientific insight with an entrepreneurial mindset, as shown by his participation in Deeptech Founders and RISE programs. His experience spans leadership, translational science, investment negotiations, and scientific mentoring.

🔬 Research Focus:

Jean-Philippe Herbeuval’s research is centered on translational immunology, particularly type I interferons, autoinflammatory pathways, and host-pathogen interactions. His work explores immune dysregulation in infectious diseases such as HIV, SARS-CoV-2, dengue, and influenza, with a special focus on the immune-modulatory roles of dendritic cells and apoptotic pathways. He has identified novel therapeutic targets including CXCR4 and PDK1, leading to two biotech start-ups and multiple patents. His interdisciplinary CBMIT team integrates immunology, virology, medicinal chemistry, and computational modeling to develop innovative therapeutic strategies and biomarkers. He has a keen interest in immunomodulation, therapeutic interference with IFN pathways, and discovery of druggable checkpoints in innate immunity. With over 70 peer-reviewed publications, his scientific output has shaped current understanding of immune pathogenesis and opened new avenues for therapy in inflammatory and infectious diseases. His approach bridges fundamental research with practical applications in drug discovery and biotech development.

📚 Publications Top Notes:

  1. 🧬 HIV inhibits CD4+ T-cell proliferation by inducing indoleamine 2,3-dioxygenase in plasmacytoid dendritic cells

  2. ⚰️ CD4+ T-cell death induced by infectious and noninfectious HIV-1: role of type 1 interferon–dependent, TRAIL/DR5-mediated apoptosis

  3. 🚻 Sex differences in plasmacytoid dendritic cell levels of IRF5 drive higher IFN-α production in women

  4. 🧪 HIV-1 immunopathogenesis: how good interferon turns bad

  5. 🔄 Regulation of indoleamine 2,3-dioxygenase and tryptophanyl-tRNA-synthetase by CTLA-4-Fc in human CD4+ T cells

  6. 🧠 Differential expression of IFN-α and TRAIL/DR5 in lymphoid tissue of progressor vs. nonprogressor HIV-1-infected patients

  7. 🧟 HIV turns plasmacytoid dendritic cells into TRAIL-expressing killer pDC via TLR7-induced IFN-α

  8. 🧬 Regulation of TRAIL on primary CD4+ T cells by HIV-1: role of plasmacytoid dendritic cells

  9. 💉 TRAIL in HIV-1–infected patients and its production by antigen-presenting cells

  10. 🧫 Recruitment of STAT3 for production of IL-10 by colon carcinoma cells induced by macrophage-derived IL-6

🧾 Conclusion:

Dr. Jean-Philippe Herbeuval stands out as a highly qualified and deserving candidate for the Best Innovator Award. His rare combination of scientific excellence, translational innovation, entrepreneurial leadership, and mentorship places him in the top tier of biomedical innovators. His work not only bridges science and industry but also directly contributes to addressing global health challenges. Continued support and recognition of his efforts will likely catalyze further innovation in therapeutic immunology.

Muhammad Junaid Anwar | Immunology Cellular Interactions | Best Researcher Award

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Mr. Muhammad Junaid Anwar | Immunology Cellular Interactions | Best Researcher Award

Mr. Muhammad Junaid Anwar , Bahauddin Zakariya Univeristy Multan Pakistan , Pakistan

Dr. Muhammad Junaid Anwar is a dedicated food scientist specializing in Food Science and Technology. With a Ph.D. from Bahauddin Zakariya University (BZU), Multan, he has established himself as a researcher with expertise in food safety, nanotechnology, and functional foods. His work focuses on developing innovative solutions for food security, nutrition, and disease prevention. Having authored multiple high-impact research publications, Dr. Anwar’s contributions span across nanotechnology-based food encapsulation, food safety enhancement, and alternative protein sources. He has also participated in prestigious conferences and workshops, further showcasing his commitment to advancing food science. His research has significantly contributed to tackling food-related health challenges such as cow milk allergies, microbial contamination, and nutraceutical applications. With his profound knowledge, industry experience, and research excellence, Dr. Anwar stands out as a promising scholar in the field. His dedication to food innovation makes him a deserving candidate for the Best Researcher Award.

Publication Profile: 

Scopus

Strengths for the Award

  1. Strong Academic Background – Dr. Muhammad Junaid Anwar has an exceptional academic record with a Ph.D. in Food Science and Technology, a strong CGPA, and an extensive research focus.

  2. High-Impact Research Publications – He has authored multiple research articles in reputable, high-impact factor journals (Ultrasonics Sonochemistry, Food Science & Nutrition, Food Bioscience, etc.). His contributions cover diverse areas, including nanotechnology, food safety, and immunomodulation.

  3. Diverse Research Contributions – His research spans crucial topics such as nano-encapsulation, diabetes management, functional foods, and nutraceuticals, demonstrating interdisciplinary expertise.

  4. Industry Experience – His experience as an Officer in Quality Enhancement and Laboratory at S.M. Food Makers highlights his applied knowledge and practical contribution to food science.

  5. Conference Participation – He has actively contributed to scientific discussions through multiple national conferences, particularly on food security and food safety.

  6. Published Abstracts & Workshops – His engagement in published abstracts and workshops reflects an effort to bridge academia with real-world food technology applications.

Areas for Improvement

  1. International Collaboration – While his research is strong, expanding collaborations with international institutions and researchers could further enhance global impact.

  2. Patent & Commercialization – Translating research into patents or commercial food innovations would strengthen his practical contributions to the industry.

  3. Citations & Recognition – As some of his latest research articles have yet to gain citations, increasing visibility through academic networks and outreach can boost recognition.

Education:

Dr. Muhammad Junaid Anwar has an exceptional academic background in Food Science and Technology. He is currently completing his Ph.D. (2021-2025) at the Department of Food Science and Technology, BZU Multan, with a stellar CGPA of 3.87/4.00. Previously, he completed his M.Sc. (Hons.) in Food Science & Technology (2018-2020) from the same institution, securing a CGPA of 3.76/4.00. His undergraduate journey began with a B.Sc. (Hons.) in Agriculture (Food Science & Technology) (2014-2018), again with a CGPA of 3.76/4.00. His solid foundation in sciences started with F.Sc. (Pre-Medical) in 2014 from Muslim Public Higher Secondary School, Multan, achieving 840/1100 marks, followed by Matriculation in 2012 from Govt. M.A Jinnah High School, Multan, with 863/1050 marks. His consistent academic excellence highlights his dedication to food science research and technological advancements, making him a strong candidate for the Best Researcher Award.

Experience:

Dr. Muhammad Junaid Anwar has a diverse professional background in food science research and industry. He completed a 7-week internship at Bunny’s Limited, Lahore, where he gained hands-on experience in food processing and quality control. He later served as an Officer (Quality Enhancement and Lab) at S.M. Food Makers for two years (2018-2020), where he worked on ensuring food safety standards and enhancing product quality. His industry experience has provided him with a deep understanding of food technology applications, quality assurance, and research methodologies. In addition to his industry roles, he has contributed to academia through extensive research on food nanotechnology, functional foods, and microbial safety. His experience spans both applied and theoretical research, making him an asset to the food science community. His professional achievements, combined with his research excellence, make him a strong contender for the Best Researcher Award.

Research Focus:

Dr. Muhammad Junaid Anwar’s research revolves around food nanotechnology, functional foods, and food safety. His recent work focuses on the nano-encapsulation of bioactive compounds, such as casein-based encapsulation for managing cow milk allergies. His contributions extend to food safety enhancements using ultrasonication and calcium chloride treatments to reduce microbial contamination in fresh produce. Dr. Anwar has also explored the nutraceutical applications of medicinal plants like fenugreek and Tribulus terrestris to develop functional foods with health benefits. His studies have highlighted the role of alternative protein sources, such as Moringa oleifera-derived proteins, in plant-based meat substitutes. Additionally, he has worked on the impact of ozone treatment in mitigating mycotoxin contamination in food. His multi-disciplinary approach to food science integrates biotechnology, food engineering, and health sciences, making his research valuable for global food security and human health. His outstanding contributions make him a strong candidate for the Best Researcher Award.

Publications Top Notes:

📌 Casein-Based Nano-Encapsulation for Cow Milk Allergy Management 🥛🔬 (Food Bioscience, 2025)
📌 Ultrasonication & Calcium Chloride Pre-Treatment for Microbial Load Reduction in Carrots 🥕🦠 (Ultrasonics Sonochemistry, 2025)
📌 Isoflavones: Natural Agents for Cancer Prevention & Treatment 🎗️🍃 (Food Science & Nutrition, 2025)
📌 Functional Yogurt with Cinnamon & Stevia for Diabetes Management 🍦🍯 (Food & Agricultural Immunology, 2024)
📌 Nutritional & Physico-Chemical Profiling of Tribulus terrestris for Nutraceutical Applications 🌿💊 (Journal of Population Therapeutics & Clinical Pharmacology, 2024)
📌 The Multifaceted Potential of Fenugreek Seeds in Health & Nanotechnology 🌱⚗️ (Food Science & Nutrition, 2024)
📌 Protein Extraction from Moringa Leaves as a Plant-Based Meat Alternative 🍃🥩 (Regulatory Toxicology & Pharmacology, 2024)
📌 Role of Ozone in Mycotoxin Management for Food Safety ⚡🍞 (PSFST Conference, 2023)
📌 Potential of Anaerobic Digestion in Food Waste Management 🔄♻️ (PSFST Conference, 2023)
📌 Addressing Food Price Fluctuations: A Global Priority 📈🌍 (PSFST Conference, 2023)
📌 Strengthening Local Food Systems for Food Security 🌾🍽️ (PSFST Conference, 2023)

Conclusion:

Dr. Muhammad Junaid Anwar has demonstrated exceptional research contributions in food science, particularly in functional foods, nanotechnology, and food safety. His high-impact publications, active participation in conferences, and industry experience make him a strong candidate for the Best Researcher Award. Strengthening international collaborations and focusing on patents or commercialization could further enhance his research impact.

Dia Aldeen Alfaki | Immunology Cellular Interactions | Best Researcher Award

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Mr. Dia Aldeen Alfaki | Immunology Cellular Interactions | Best Researcher Award

Mr. Dia Aldeen Alfaki , Alzaiem Alazhari University , Sudan

Dia Alfaki is a Sudanese biomedical scientist with a Master of Biomedical Sciences and extensive experience in haematology, molecular biology, and immunology. His research focuses on the complexities of disease mechanisms and therapeutic solutions, particularly within immunology. As a junior researcher and PG Member of the British Society of Immunology, Dia has contributed significantly to studies on malaria and immune responses. His academic background includes a Master’s degree from Alzaiem Alazhari University and a Bachelor’s degree from Omdurman Islamic University. Dia’s dedication to understanding disease complexities through research is reflected in his growing academic presence and expertise in clinical laboratory techniques. He is committed to advancing scientific knowledge and improving healthcare solutions through his research endeavors.

Publication Profile: 

Orcid

Strengths for the Award:

Dia Alfaki has a remarkable blend of educational qualifications, practical experience, and academic research, making him highly suitable for the Research for Best Researcher Award. His work spans critical areas in biomedical sciences, with a special focus on immunology, haematology, and molecular biology, especially in relation to infectious diseases like malaria. His Master’s research on immune responses to Plasmodium falciparum infection stands out, demonstrating his ability to identify novel immunological markers. His published work in well-regarded journals like Microbiologia Medica and Immunology & Cell Biology further showcases his expertise. He has actively contributed to the scientific community through various international conferences, highlighting his commitment to advancing research. His work at G42 Healthcare underscores his technical skills in molecular diagnostics and cutting-edge biomedical research. His collaborative nature, critical thinking, and proven leadership in research make him a strong contender for this award.

Areas for Improvement:

While Dia Alfaki has a solid foundation in immunology and biomedical research, further expansion of his research portfolio into diverse therapeutic fields could enhance his profile. Gaining more experience in clinical settings beyond molecular labs could provide him with a broader perspective in healthcare applications. Additionally, his involvement in multi-disciplinary research collaborations across diverse disease areas such as oncology and genomics would elevate his impact on global biomedical challenges. Developing greater expertise in bioinformatics tools and integrating them into his molecular research would further refine his analytical skills and position him as an even more influential scientist in his field.

Education:

Dia Alfaki holds a Master’s degree in Biomedical Sciences from Alzaiem Alazhari University (2014-2016), where he specialized in Medical Laboratory Sciences with a focus on Haematology and Blood Transfusion, achieving a CGPA of 3.19/4.0. He completed his Bachelor’s degree in Medical Laboratory Sciences from Omdurman Islamic University (2007-2011), where he excelled in Hematology and Immunohematology. Additionally, Dia is pursuing certification as an International Medical Lab Technologist in Hematology (ASCPi) from the American Society for Clinical Pathology (2022-2025). His academic and professional development demonstrates a strong foundation in biomedical sciences, preparing him to make significant contributions to immunology research and clinical diagnostics.

Experience:

Dia Alfaki has worked as a Molecular Lab Technologist at G42 Healthcare (Biogenix Molecular Labs) from 2020-2023, contributing to advanced molecular research and diagnostics. His expertise spans a wide range of laboratory techniques, particularly in immunology, molecular biology, and hematology. Throughout his career, Dia has been involved in various research projects, including his Master’s thesis focused on the immune response to Plasmodium falciparum infection. He has also contributed to several high-impact publications, collaborating with experts in the field of malaria, immune phagocytosis, and cancer immunology. His role in molecular diagnostics has allowed him to apply his research findings to real-world clinical settings, furthering the understanding of disease pathology and therapeutic interventions.

Awards and Honors:

Dia Alfaki has been recognized for his significant contributions to biomedical science, particularly in immunology research. He participated in prominent international conferences, including the 6th European Congress of Immunology (2022) and the American Association for Cancer Research Annual Meeting (2021). His ongoing work in malaria immunology and cancer immunology is highly regarded in scientific communities. As a PG Member of the British Society of Immunology since 2021, Dia continues to gain recognition for his research on immune responses and inflammation. His work has also been highlighted in various prestigious journals, where his research on malaria and immune responses has earned accolades. These honors reflect his commitment to advancing scientific knowledge and improving healthcare through rigorous research.

Research Focus:

Dia Alfaki’s research is primarily focused on immunity, inflammation, cancer immunology, and molecular oncology. His work emphasizes understanding disease mechanisms, particularly the immune responses involved in infections like malaria and the pathogenesis of diseases such as cancer. Dia is particularly interested in the role of immune mediators, phagocytosis, and molecular interactions in disease progression and therapy. His research aims to explore therapeutic perspectives in immunology, using molecular and cellular approaches to better understand disease complexities and improve treatment options. His publications highlight these areas, especially in the context of malaria and inflammatory immune responses. Dia is also committed to utilizing molecular techniques and bioinformatics tools to contribute to new therapeutic strategies for immunological diseases.

Publications Top Notes:

  1. Patterns of Mannose-Binding Lectin (MBL) responses to Plasmodium falciparum infections in hyperendemic settings 📚🔬
  2. Inflammatory immune mediators and Plasmodium falciparum infection: a cross-sectional study among Sudanese patients with severe and uncomplicated malaria 🌍🦠
  3. Monocytes to lymphocytes ratio in peripheral blood and immunoglobulin IgE levels as indicators to Plasmodium falciparum infection in Sudan 📖🔬
  4. The colorectal cancer microenvironment: Preclinical progress in identifying targets for cancer therapy 🦠🔬
  5. Plasmodium falciparum and immune phagocytosis: characterization of the process 🦠💉

Conclusion:

Dia Alfaki is an outstanding researcher with a well-rounded background in biomedical sciences, molecular biology, and immunology. His research accomplishments, publications, and contributions to international conferences highlight his drive for advancing scientific knowledge, particularly in the area of disease mechanisms and immune responses. His strong academic foundation, coupled with his practical lab experience and active engagement with the scientific community, positions him as an excellent candidate for the Research for Best Researcher Award. With a few areas of growth in clinical practice and cross-disciplinary collaborations, he has the potential to become a leader in global biomedical research.