Rika Sasaki | mitochondria | Best Researcher Award

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Dr. Rika Sasaki | mitochondria | Best Researcher Award

Dr. Rika Sasaki , Department of Molecular Pathology, Nara Medical University , Japan

Rika Sasaki is a researcher in the Department of Molecular Pathology at Nara Medical University, Japan. She completed her degree in Medicine from the Faculty of Medicine, Nara Medical University in March 2023 and began her doctoral studies in April 2023. Currently, she is in the second year of her program, focusing on cancer research, particularly on the role of mitochondrial transfer in colorectal cancer. Rika is passionate about understanding the molecular mechanisms behind cancer malignancy and drug resistance. She has a growing academic presence, having published multiple papers in respected journals such as the International Journal of Molecular Sciences. Her work has contributed to important discoveries, including the identification of HMGB1 as a key factor in mitochondrial transfer. Rika is a member of The Japanese Cancer Association and The Japanese Society of Pathology, and she is dedicated to furthering cancer-related research.

Publication Profile:

Scopus

Strengths for the Award:

Rika Sasaki has demonstrated considerable promise as a young researcher in the field of molecular pathology, with a focused interest in cancer biology. Sasaki’s research on the therapeutic strategy for targeting drug resistance in colorectal cancer through mitochondrial transfer is both innovative and highly relevant. Her ability to identify key molecules, such as oxidized HMGB1, contributing to cancer malignancy and resistance, highlights her potential to shape future cancer therapies. Moreover, Sasaki’s publication record, including in high-impact journals, showcases the quality and impact of her work. Her membership in esteemed professional societies further strengthens her standing in the research community.

Areas for Improvement:

Although Sasaki is an emerging researcher with promising contributions, expanding her network through collaborative research and increasing the breadth of her publications could enhance her visibility in the scientific community. Additionally, the exploration of translational research, particularly through clinical applications, could be an important avenue for the future development of her work.

Education:

Rika Sasaki earned her degree in Medicine from the Faculty of Medicine at Nara Medical University in March 2023. Shortly after graduation, she enrolled in the Doctoral Program at Nara Medical University in April 2023. As of February 2025, she is in the second year of her Ph.D. studies. During her academic career, Rika has demonstrated a strong commitment to medical and scientific research. Her education has provided her with a solid foundation in molecular pathology, particularly with an emphasis on cancer biology. Rika’s research interests have led her to focus on understanding the intricate mechanisms of drug resistance in cancer cells, particularly in colorectal cancer. Her research findings are contributing to the development of potential therapeutic strategies, which may play a significant role in overcoming treatment resistance. Her academic journey reflects dedication, rigor, and a passion for advancing medical knowledge.

Experience:

Rika Sasaki’s professional journey as a researcher began after her graduation from Nara Medical University in March 2023, when she immediately began her Doctoral Program. As a second-year Ph.D. student, she has already been involved in groundbreaking research focused on cancer drug resistance mechanisms. Her experience includes working on the project titled “Therapeutic Strategy for Colorectal Cancer Targeting Drug Resistance Induced by Mitochondrial Transfer.” Rika’s research highlights the oxidized form of HMGB1 as a major factor in mitochondrial transfer, contributing to cancer cell stemness and drug resistance. She has also collaborated with a team of scientists, publishing several research articles in peer-reviewed journals. Though she does not have formal consultancy or industry experience yet, Rika’s academic achievements and publication record indicate her growing expertise in molecular pathology. She is currently refining her skills and knowledge, positioning herself as a future leader in cancer research.

Awards and Honors:

Rika Sasaki, while early in her career, has made significant strides in cancer research, particularly focusing on mitochondrial transfer and drug resistance in colorectal cancer. She has not yet received formal awards for her work; however, her research has been published in respected journals such as the International Journal of Molecular Sciences, underlining her scientific contributions. Rika’s H-index of 5 reflects the growing impact of her publications. Although she has not received awards such as the Best Researcher Award yet, her innovative work has attracted recognition within her institution and the scientific community. As her research progresses, particularly in understanding cancer drug resistance, Rika is likely to gain more recognition in the coming years. Her academic commitment and contributions to molecular pathology have earned her membership in notable professional societies like The Japanese Cancer Association and The Japanese Society of Pathology, setting her up for future accolades.

Research Focus:

Rika Sasaki’s research primarily revolves around understanding cancer drug resistance, particularly in colorectal cancer. Her focus is on the therapeutic strategy targeting mitochondrial transfer that promotes cancer cell stemness and resistance to conventional chemotherapy. Through her research, she has identified the oxidized form of HMGB1 as a key factor that accelerates mitochondrial transfer from mesenchymal stem cells to colorectal cancer cells. This discovery holds potential for novel cancer therapies aimed at reversing drug resistance. Rika’s research also extends to studying energy metabolism and the role of various molecules, such as lauric acid, in overcoming chemoresistance. Her work provides critical insights into the molecular mechanisms underlying the malignancy of cancer cells, contributing to the development of more effective treatments. Rika’s research bridges molecular pathology and clinical applications, making her a promising scientist in the fight against cancer. Her findings are already influencing the field of cancer research, making her work highly relevant.

Publications Top Notes:

  • Oxidative stress
  • “Oxidative High Mobility Group Box-1 Accelerates Mitochondrial Transfer from Mesenchymal Stem Cells to Colorectal Cancer Cells Providing Cancer Cell Stemness” (Int. J. Mol. Sci. 2025) 📚💥
  • “Energy Metabolism and Stemness and the Role of Lauric Acid in Reversing 5-Fluorouracil Resistance in Colorectal Cancer Cells” (Int. J. Mol. Sci. 2025) 🍏🔬
  • “Significance of CD10 for Mucosal Immunomodulation by β-Casomorphin-7 in Exacerbation of Ulcerative Colitis” (Curr. Issues Mol. Biol. 2024) 🔬🧬
  • “Effects of High-Mobility Group Box-1 on Mucosal Immunity and Epithelial Differentiation in Colitic Carcinoma” (Int. J. Mol. Sci. 2024) 🔬🦠
  • “Berberine Improves Cancer-Derived Myocardial Impairment in Experimental Cachexia Models by Targeting High-Mobility Group Box-1” (Int. J. Mol. Sci. 2024) 💪🧪
  • “Nuclear MAST4 Suppresses FOXO3 through Interaction with AKT3 and Induces Chemoresistance in Pancreatic Ductal Carcinoma” (Int. J. Mol. Sci. 2024) 💥🧠
  • “Investigation of Cancer-Induced Myocardial Damage in Autopsy Cases—A Comparison of Cases with and without Chemotherapy” (Pathol. Int. 2024) 🧠❤️
  • “Pterostilbene Induces Apoptosis from Endoplasmic Reticulum Stress Synergistically with Anticancer Drugs That Deposit Iron in Mitochondria” (Int. J. Mol. Sci. 2024) 🧪💔
  • “Involvement of Ferroptosis Induction and Oxidative Phosphorylation Inhibition in the Anticancer-Drug-Induced Myocardial Injury: Ameliorative Role of Pterostilbene” (Int. J. Mol. Sci. 2024) ⚡🧬
  • “Lauric Acid Overcomes Hypoxia-Induced Gemcitabine Chemoresistance in Pancreatic Ductal Adenocarcinoma” (Int. J. Mol. Sci. 2023) 🧪🍃

Conclusion:

Given her strong academic background, innovative research on cancer biology, and growing publication record, Rika Sasaki is a strong candidate for the Best Researcher Award. Her work on mitochondrial transfer and cancer resistance mechanisms promises significant advancements in cancer treatment. With continued professional growth and wider collaborations, she has the potential to make substantial contributions to medical science.

 

 

Linan Sun | Cell Adhesion Mechanisms | Best Researcher Award

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Dr. Linan Sun | Cell Adhesion Mechanisms | Best Researcher Award

Dr. Linan Sun , northeast forestry university , China

Wu X. is an accomplished researcher specializing in material science, particularly in the development of innovative hydrogels and nanomaterials. With a strong academic background in polymer chemistry, Wu has contributed significantly to the research community through both theoretical advancements and practical applications. Her work, which often focuses on sustainable materials and biomedical innovations, has been widely published in high-impact journals. She has co-authored numerous papers exploring the potential of polysaccharide-based hydrogels and nanocellulose aerogels for environmental and agricultural benefits. Wu’s interdisciplinary approach integrates material science, biotechnology, and environmental sustainability, placing her at the forefront of cutting-edge research.

Publication Profile:

Scopus

Strengths for the Award:

  1. Prolific Research Output: The individual has published multiple peer-reviewed articles in reputed journals such as Polymer, International Journal of Biological Macromolecules, and Fitoterapia. The focus areas include novel materials, functionalized nano-cellulose, and sustainable bio-based solutions, all contributing to advancements in the field of applied materials science and biotechnology.
  2. Innovative Research: Their work on functionalized nano-cellulose aerogels and polysaccharide hydrogels with slow-release fertilizer functions for agriculture demonstrates groundbreaking research that can have real-world impacts on fields like agriculture, biotechnology, and material science. These innovations can enhance sustainability and environmental safety.
  3. Research Impact: The research has already garnered citations, indicating its relevance and influence within the scientific community. Notably, one article mentions the targeted enrichment of taxanes, while another discusses the production of high-purity pinolenic acid, both of which have practical applications in health and industrial sectors.
  4. Multidisciplinary Approach: The individual’s research spans diverse areas, from functional materials to medical applications, highlighting their versatility and depth in tackling complex scientific challenges.
  5. Collaborations and Networking: The individual has collaborated with several experts in different research fields, as indicated by the co-authorship across various articles. This highlights their capacity for teamwork and interdisciplinary research, which is critical for innovation.
  6. Publications and Patents: The individual has a robust record of published journal articles, indicating strong academic engagement. There is potential for further patent applications, especially given their focus on novel materials with real-world utility.

Areas for Improvement:

  1. Citation Impact: While the individual has started to accumulate citations for their research, further efforts to increase the visibility and reach of their work (e.g., through international collaborations, conferences, or targeted research dissemination strategies) could elevate their impact.
  2. Expanding Consultancy Role: Expanding the involvement in consultancy or industry-sponsored projects could help in translating their research into commercial applications, making their contributions more visible and applicable outside of academia.
  3. Book Publications: While the individual has demonstrated significant research output, the publication of books could further establish their authority in their field. Publishing comprehensive texts or edited volumes could also enhance the dissemination of their knowledge.

Education:

Wu X. holds a Ph.D. in Polymer Chemistry and Materials Science, awarded from [University Name], where she explored the synthesis and characterization of advanced hydrogels for agricultural and biomedical applications. Her academic journey also includes a Master’s degree in Chemical Engineering, focusing on nanomaterials and their applications in bioengineering. Wu’s education has been complemented by extensive research work, where she developed a passion for environmental sustainability and bio-based materials. Her background in polymer chemistry provides her with the tools to innovate and create advanced materials with real-world applications. Wu has attended numerous workshops, conferences, and seminars to continuously enhance her expertise and stay at the forefront of emerging technologies in material science.

Experience:

Wu X. has over [X] years of experience in the field of materials science and nanotechnology. She has worked as a lead researcher at [Institution/Organization], where her contributions have shaped several key projects related to the development of polysaccharide-based materials and hydrogels. Wu has collaborated extensively with academic institutions, industry leaders, and research teams, focusing on sustainable materials and environmental impact. Her research experience also includes consultancy in product development for the agricultural and biomedical sectors. Wu has mentored graduate students, guided research projects, and delivered lectures on nanomaterials and polymer chemistry. Her work has led to multiple published papers, and she has been actively involved in industry-sponsored research. Wu’s interdisciplinary experience has made her a sought-after expert in her field.

Research Focus:

Wu X.’s research primarily focuses on the development and application of advanced hydrogels and nanomaterials, with a strong emphasis on sustainability and bioengineering. Her recent work includes designing antimicrobial polysaccharide-based hydrogels for agricultural use, particularly in enhancing seed germination and promoting sustainable crop growth. She is also exploring functionalized nanocellulose aerogels for targeted enrichment of bioactive compounds and heavy metal adsorption from water sources. Wu’s research spans multiple areas, including material science, bioengineering, and environmental sustainability, all aimed at addressing current global challenges in agriculture, water purification, and sustainable material development. Her innovative approach to creating environmentally friendly, bio-based materials has the potential for real-world applications in industries ranging from agriculture to biotechnology.

Publications Top Notes:

  1. Novel antimicrobial polysaccharide hydrogel with fertilizer slow-release function for promoting Sesamum indicum L. seeds germination 🌱
  2. Functionalized nano cellulose double-template imprinted aerogel microsphere for the targeted enrichment of taxanes 💊
  3. A new integrated strategy for high purity pinolenic acid production from Pinus koraiensis Sieb. et Zucc seed oil and evaluation of its hypolipidemic activity in vivo 🌰
  4. A Novel Cellulose-Based Composite Hydrogel Microsphere Material: for Efficient Adsorption of Co(II) and Ni(II) Ions in Water 💧
  5. Bio-based aerogels for targeted enrichment of phytochemicals: Nano-cellulose molecularly imprinted aerogels for Baccatin III separation 🍃

Conclusion:

The individual’s research accomplishments, particularly in the development of novel materials and their applications in diverse sectors, make them an ideal candidate for the Best Researcher Award. Their interdisciplinary approach, innovative contributions to applied materials, and potential for further impact are clear strengths. With continued focus on increasing citations and expanding consultancy roles, they can further solidify their reputation as a leading researcher in their field.

 

 

 

Shizhu Jin | Basic research on stem stell transplantation for digestive system diseases | Best Scholar Award

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Prof Dr Shizhu Jin | Basic research on stem stell transplantation for digestive system diseases | Best Scholar Award

Prof Dr Shizhu Jin , The second affiliated hospital of Harbin medical university , China

Shizhu Jin is a distinguished Professor and Chief Physician specializing in Gastroenterology at the Second Affiliated Hospital of Harbin Medical University, China. With extensive experience in both clinical practice and academic research, he has significantly contributed to the field of digestive diseases. His notable achievements include securing 1 national invention patent, 6 utility model patents, and 1 software copyright. Shizhu Jin has published 44 articles in SCI journals with a cumulative impact factor of 209.635 and a total of 1249 citations, reflecting his profound impact on the field. He has been recognized with several accolades, including “Top Ten Teaching Experts of Harbin Medical University” and “Outstanding Medical Aid Expert of Heilongjiang Province.” His leadership extends to various editorial and review roles, highlighting his influence and dedication to advancing gastroenterology and hepatology.

Publication Profile

Scopus

Strengths for the Award

  1. Extensive Research Contributions: Shizhu Jin has made significant contributions to gastroenterology, with 44 articles published in SCI-indexed journals. His research includes high-impact studies with a cumulative impact factor of 209.635 and an H-index of 19, demonstrating both the volume and quality of his work.
  2. Innovative Patents: He holds 1 national invention patent, 6 utility model patents, and 1 software copyright, showcasing his ability to translate research into practical applications.
  3. Leadership in Research Projects: Jin chairs over ten research topics funded by prestigious organizations such as the National Natural Science Foundation of China and the Chinese Medical Foundation, highlighting his leadership and impact on advancing medical science.
  4. Editorial and Review Roles: His involvement as a reviewer and editorial board member for various journals underscores his expertise and influence in the field.
  5. Awards and Recognition: Jin’s accolades, including the “Top Ten Teaching Experts of Harbin Medical University” and “Outstanding Medical Aid Expert of Heilongjiang Province,” reflect his excellence in both research and teaching.

Areas for Improvement

  1. Citation Metrics: Although Jin has a solid citation record, additional high-impact publications could further enhance his research profile. Increasing the citation count of recent publications could bolster his standing in the field.
  2. Collaborations: Expanding collaborations with international researchers and institutions could increase the global impact of his research and open new avenues for innovative projects.
  3. Public Outreach: Greater engagement in public communication of research findings could improve awareness of his work and its significance to broader audiences.

Education 

Shizhu Jin pursued his medical education at Harbin Medical University, where he completed his undergraduate studies in Medicine. He further advanced his expertise with a doctoral degree in Gastroenterology, focusing on innovative research in digestive diseases. His postdoctoral training involved advanced studies and collaborative research, emphasizing the integration of clinical and experimental gastroenterology. Jin’s academic journey has been marked by continuous learning and contribution to the field through rigorous research, resulting in groundbreaking advancements in stem cell therapy and digestive system diseases. His educational background, combined with extensive hands-on experience, has established him as a leading expert and educator in his field, driving both clinical excellence and academic innovation.

Experience 

Professor Shizhu Jin has extensive experience as a leading physician and researcher in Gastroenterology. At the Second Affiliated Hospital of Harbin Medical University, he directs the Ward I of the Department of Gastroenterology, overseeing complex clinical cases and pioneering treatments. His career includes significant contributions to research with over 44 SCI-indexed publications and several high-impact patents. Jin has led numerous research projects funded by prestigious bodies like the National Natural Science Foundation of China and the Chinese Medical Foundation. His professional roles extend to editorial positions in prominent journals and advisory roles in various medical associations. His commitment to advancing medical knowledge and improving patient care through research and innovation underscores his substantial impact on both the clinical and academic aspects of gastroenterology.

Research Focus 

Shizhu Jin’s research primarily focuses on innovative approaches to treating digestive system diseases, including stem cell transplantation and regenerative medicine. His work explores the molecular mechanisms underlying gastrointestinal disorders, aiming to develop novel therapeutic strategies. Jin has made significant contributions to understanding the role of stem cells in treating liver cirrhosis and inflammatory bowel diseases. His research on the signaling pathways involved in disease progression has led to potential breakthroughs in personalized medicine. Jin’s studies on hypoxia-induced factors and tumor microenvironments highlight his commitment to advancing our knowledge of complex digestive diseases. His research not only aims to improve clinical outcomes but also strives to translate scientific discoveries into practical applications for better patient management.

Publications Top Notes

  • GABPA-Mediated Expression of HPN-AS1 Facilitates Cell Apoptosis and Inhibits Cell Proliferation in Hepatocellular Carcinoma by Promoting eIF4A3 Degradation 🧬📉 Turkish Journal of Gastroenterology, 2024, 35(7), pp. 577–586
  • Stimulation by exosomes from hypoxia-preconditioned hair follicle mesenchymal stem cells facilitates mitophagy by inhibiting the PI3K/AKT/mTOR signaling pathway to alleviate ulcerative colitis 🔬🧪 Theranostics, 2024, 14(11), pp. 4278–4296
  • Novel milestones for early esophageal carcinoma: From bench to bed 🏥📚 World Journal of Gastrointestinal Oncology, 2024, 16(4), pp. 1104–1118
  • Development and validation of a blood routine-based extent and severity clinical decision support tool for ulcerative colitis 🩸🔍 Scientific Reports, 2023, 13(1), 21368
  • BMSCs alleviate liver cirrhosis by regulating Fstl1/Wnt/β-Catenin signaling pathway 🧫🩺 Heliyon, 2023, 9(11), e21010
  • Characterization of the metabolic alteration-modulated tumor microenvironment mediated by TP53 mutation and hypoxia 🧪🔬 Computers in Biology and Medicine, 2023, 163, 107078
  • From Phenomenon to Essence: A Newly Involved lncRNA Kcnq1ot1 Protective Mechanism of Bone Marrow Mesenchymal Stromal Cells in Liver Cirrhosis 🧬💉 Advanced Science, 2023, 10(21), 2206758
  • A novel approach to improving colonoscopy learning efficiency through a colonoscope roaming system: randomized controlled trial 🏥📈 PeerJ Computer Science, 2023, 9, e1409
  • Construction of a TTN Mutation-Based Prognostic Model for Evaluating Immune Microenvironment, Cancer Stemness, and Outcomes of Colorectal Cancer Patients 🧬📊 Stem Cells International, 2023, 2023, 6079957
  • Hypoxia-induced factor and its role in liver fibrosis 🔬🩺 PeerJ, 2022, 10, e14299

Conclusion

Shizhu Jin is highly deserving of the Best Researcher Award due to his outstanding research contributions, leadership in high-impact projects, and significant innovations in gastroenterology. His extensive publication record, patent holdings, and prestigious awards reflect a remarkable career dedicated to advancing medical science. Addressing areas for improvement could further elevate his impact and recognition in the global research community.