Afef Najjari | Bioinformatics | Women Researcher Award

Assist. Prof. Dr. Afef Najjari | Bioinformatics | Women Researcher Award

Assist. Prof. Dr. Afef Najjari | Faculty of sciences of Tunisia/University of Tunis el Manar | Tunisia

Dr. Afef Najjari is an Assistant Professor in Biomedical Engineering, specializing in Bioinformatics at the Faculty of Sciences of Tunis. Her academic journey is marked by deep engagement in microbial genomics, with a particular focus on extremophilic microorganisms from the Tunisian desert. Dr. Najjari has authored over 17 peer-reviewed research papers and 2 book chapters, collaborating on international projects that explore genomics, environmental microbiology, and bioremediation. She has taught bioinformatics and genomics at institutions like ISBST and has mentored numerous master’s and PhD students. Her work contributes to understanding microbial diversity and biotechnological applications, particularly in arid ecosystems. With active involvement in teaching, supervision, and research, Dr. Najjari is a role model for young women entering STEM fields in Tunisia and beyond.

Publication Profile: 

Scopus

Education:

Dr. Najjari holds advanced degrees in Biological Sciences and Bioinformatics, culminating in a Ph.D. focused on microbial genomics and environmental microbiology. Her academic foundation combines traditional biology with computational and data-driven sciences. Though specific degree names or institutions aren’t listed, her roles in research and teaching suggest completion of doctoral training in a relevant biological discipline, followed by postdoctoral experience or academic training in genomics. Her integration into faculty positions at institutions such as the Faculty of Sciences of Tunis and ISBST further implies strong academic credentials, likely earned through nationally or internationally accredited programs. She effectively blends her biological background with technical bioinformatics applications, enabling interdisciplinary teaching and research.

Experience:

Dr. Najjari has over a decade of experience in academia, research, and mentorship. Since 2014, she has taught Genomics and Bioinformatics at ISBST and currently at the Faculty of Sciences of Tunis. She has supervised 11 graduate students across master’s and PhD levels. Her research centers on microbial genomics, metataxonomics, pan-genomics, and bioremediation, particularly in extreme environments like saline and geothermal oases. As an Assistant Professor in Biomedical Engineering, she skillfully integrates molecular biology with computational science. Beyond publishing in leading journals, she engages in collaborative, interdisciplinary research projects. Her dual role as educator and researcher allows her to train future bioinformaticians while advancing knowledge in microbial adaptation, iron uptake, and heavy metal remediation.

Research Focus:

Dr. Najjari’s research explores the genomic and functional diversity of extremophiles, focusing on halophilic archaea and bacteria from desert and saline ecosystems in Tunisia. She applies bioinformatics pipelines to understand microbial adaptation to harsh conditions, including iron uptake, oil degradation, and biopolymer production. Her projects use pan-genome analysis, 16S rRNA metataxonomics, and functional genomics to identify microbial traits valuable in bioremediation, such as flocculation of heavy metals and pesticides. Her work advances the understanding of environmental microbiomes and their industrial and ecological potential. Recently, she has extended her research to include the gut microbiome of honeybees and livestock genomics, contributing to biodiversity preservation. Her focus is timely and relevant, addressing global environmental challenges with sustainable biotechnological solutions.

Publications Top Notes:

  1. Genome and pan-genome analysis of Psychrobacillus sp.Front. Microbiol.,

  2. Physiological and genomic insights into halophilic archaeon Natrinema altunenseGenetica,

  3. 16S rRNA phylogenetic diversity of archaeal communities in Saharan halite saltsBiology (Basel),

  4. Metataxonomics of Tunisian phosphogypsum using five bioinformatics pipelinesGenomics,

  5. Flocculating heteropolysaccharide–protein from haloarchaea for heavy metals removalEnvironmental Technology,

  6. Genome analysis of Halomonas desertis G11 for oil degradation and biosurfactant productionGenomes,

  7. Pseudomonas rhizophila S211 for pesticide bioremediation and plant growthFront. Microbiol.,

  8. Microbiota of whitefly Bemisia tabaci via 16S rDNA sequencingMicrobiology Research,

  9. Genome-wide selection scans in fat- vs. thin-tailed North African sheepAnimal Genetics,

  10.  Metataxonomic analysis of halophiles in geothermal oases of southern TunisiaFEMS Microbiol. Lett.,

Conclusion:

Dr. Afef Najjari is a highly suitable candidate for the Research for Women Researcher Award. Her innovative research in bioinformatics and microbial genomics, particularly in extreme and underexplored ecosystems of Tunisia, not only advances scientific knowledge but also addresses pressing environmental challenges. Her dedicated teaching and supervision record, combined with her technical expertise, exemplify academic excellence and leadership. While expanding her engagement in women-focused STEM initiatives and international research programs could further amplify her impact, her existing contributions already position her as a key figure in North African science. Recognizing Dr. Najjari with this award would celebrate her scientific achievements and inspire broader participation of women in high-impact research fields.

ALINE TAKEJIMA | Tissue engineering | Women Researcher Award

Dr. ALINE TAKEJIMA | tissue engineering | Women Researcher Award

Dr. ALINE TAKEJIMA, pontificia universidade catolica do parana, Brazil

Dr. Aline Luri Takejima is a physician-scientist from Brazil, specializing in regenerative medicine and wound healing. She holds an MD and a PhD in Health Sciences from the Pontifical Catholic University of Paraná (PUCPR), where she currently conducts postdoctoral research. With a focus on biological therapies involving the amniotic membrane, Wharton’s jelly, and mononuclear stem cells, Dr. Takejima has published in multiple high-impact scientific journals. Her research aims to develop novel regenerative strategies to treat complex wounds and enhance tissue repair. As an active member of PUCPR’s Wound Healing Research Group and the Brazilian Society of Plastic Surgery, she combines scientific rigor with clinical insight to bridge bench-to-bedside innovation. Her academic contributions are guided by a translational approach, offering promising avenues for future clinical applications in tissue engineering.

Publication Profile: 

Orcid

✅ Strengths for the Award:

  1. Focused Research Excellence:
    Dr. Takejima’s work on biological scaffolds and stem cells in wound healing is both innovative and clinically relevant. Her studies using amniotic membrane, Wharton’s jelly, and bone marrow mononuclear cells show promising regenerative outcomes in preclinical models.

  2. Research Productivity:
    With 9 peer-reviewed journal articles in high-quality platforms (e.g., Biomedicines, Tissue Barriers, Annals of Biomedical Engineering), she demonstrates consistent academic output in her field.

  3. Translational Impact:
    Her research bridges basic science and clinical practice, aiming to provide regenerative solutions for patients with chronic wounds and cardiac damage.

  4. Collaborative Engagement:
    Active participation in a multidisciplinary wound healing research group, contributing to cross-functional scientific advancements.

  5. Recognition Potential:
    As a young, emerging woman researcher in biomedical sciences, she stands as a role model for future female scientists in Latin America and beyond.

🔧 Areas for Improvement:

  1. Intellectual Property & Innovation:
    No patents filed yet; transitioning her research into patentable therapies or commercial applications would increase its societal and economic impact.

  2. Leadership Roles:
    While active in research, taking on editorial or scientific leadership positions would enhance her academic visibility and influence.

  3. Internationalization:
    She would benefit from developing international collaborations or fellowships to diversify her research scope and increase global reach.

  4. Industry Engagement:
    Engaging in consultancy or biotech partnerships can further the translational impact of her regenerative strategies.

🎓 Education:

Dr. Takejima’s educational journey began with a Doctor of Medicine (MD) degree from the Pontifical Catholic University of Paraná (PUCPR), Brazil. Her passion for research led her to pursue a Doctorate (PhD) in Health Sciences/Medicine, also at PUCPR. Her doctoral thesis focused on the use of biologically active materials such as the amniotic membrane and stem cells to enhance wound healing. Throughout her academic training, she demonstrated a strong commitment to translational medicine by integrating basic science with clinical practice. During her PhD, she engaged in experimental models involving stem cell therapy and tissue engineering, which laid the groundwork for her current postdoctoral research. Her educational path reflects both depth and specialization in the biomedical sciences, particularly in regenerative medicine and cellular therapies.

💼 Experience:

Dr. Aline Takejima has over a decade of experience in medical and scientific fields, balancing her role as a physician with that of a postdoctoral researcher. Her clinical background informs her research, particularly in areas of wound healing and regenerative medicine. At PUCPR, she contributes to the Wound Healing Research Group, where she is involved in designing and conducting animal model studies to test the effects of biomaterials and stem cells. Her multidisciplinary research integrates immunology, histopathology, and molecular biology. With nine peer-reviewed publications and participation in collaborative research, she has become a respected contributor to the field. Though early in her research career, her trajectory shows a steady rise, marked by evidence-based outcomes and a commitment to innovation. Her goal is to bridge clinical challenges with regenerative solutions that can be implemented in real-world medical practice.

🔬 Research Focus:

Dr. Takejima’s research focuses on regenerative strategies for wound healing, utilizing biomaterials and stem cells. Her work primarily explores the application of amniotic membrane, Wharton’s jelly, and bone marrow-derived mononuclear stem cells in treating complex or chronic skin wounds. Using experimental models in rats and rabbits, she evaluates histological recovery, inflammation modulation, and tissue regeneration. A significant aspect of her research is understanding how these materials promote healing through paracrine effects rather than direct integration, offering a safer and scalable pathway to clinical application. Additionally, her work extends to cardiac and tracheal tissue repair, emphasizing the versatility of these regenerative approaches. The translational nature of her research bridges laboratory discoveries with potential bedside applications, positioning her at the forefront of cellular therapy and biomaterials science.

📚 Publications Top Notes:

  1. 🧠 Wharton’s Jelly Bioscaffolds Improve Cardiac Repair with Bone Marrow Mononuclear Stem Cells in RatsJournal of Functional Biomaterials, 2025

  2. 🧫 The effects of decellularized amniotic membrane and Wharton’s jelly on the healing of experimental skin wounds in ratsTissue Barriers, 2025

  3. ❤️ Bone-marrow mononuclear cells and acellular human amniotic membrane improve global cardiac function…Anais da Academia Brasileira de Ciências, 2024

  4. 🫁 Tracheal regeneration with acellular human amniotic membrane and 15d-PGJ2 nanoparticles in rabbitsAnais da Academia Brasileira de Ciências, 2023

  5. 🧬 Acellular Biomaterials + Autologous Stem Cells Improve Wound Healing via Paracrine EffectsBiomedicines, 2023

  6. 💉 Decellularized Amniotic Membrane Solubilized with Hyaluronic Acid in Wound HealingAnnals of Biomedical Engineering, 2022

  7. 🧪 Role of Mononuclear Stem Cells and Decellularized Amniotic Membrane in Skin WoundsTissue Barriers, 2022

  8. 🏥 Trauma hepático: epidemiologia de cinco anos…Revista do Colégio Brasileiro de Cirurgiões, 2008

🧾 Conclusion:

Dr. Aline Luri Takejima is an outstanding candidate for the Women Researcher Award. Her academic profile demonstrates a strong foundation in regenerative medicine with significant contributions to wound healing research. Her commitment to applying biological therapies in clinical contexts shows both depth and innovation. As a woman scientist in a competitive field, she exemplifies leadership, dedication, and potential. With further growth in global engagement and innovation strategy, Dr. Takejima is poised to become a future leader in regenerative biomedical research.