Dr. Arvind Singh Negi , csir-cimap , India
Dr. Arvind Singh Negi, born on January 1, 1970, is a prominent scientist in the field of medicinal chemistry, currently serving as Chief Scientist and Head of the Phytochemistry Division at CSIR-Central Institute of Medicinal and Aromatic Plants, Lucknow, India. With a distinguished academic background and over three decades of experience, he specializes in natural product chemistry and the development of cancer chemotherapeutics. Dr. Negi has published extensively, contributing significantly to the understanding of plant-based medicinal compounds. His work has garnered numerous accolades, reflecting his commitment to advancing science in medicinal chemistry and natural products.
Publication Profile
Google Scholar
Strengths for the Award
Dr. Arvind Singh Negi possesses a robust academic background and extensive experience in medicinal chemistry, particularly in the development of cancer therapeutics from natural products. His impressive publication record, with over 106 research papers and significant citations, showcases his impact on the field. His leadership as Chief Scientist at CSIR-CIMAP reflects his ability to drive innovative research initiatives. Additionally, his multiple prestigious awards and fellowships, including recognition from the Royal Society of Chemistry and the National Academy of Sciences, underscore his scientific contributions and collaborations on a global scale.
Areas for Improvement
While Dr. Negi’s research achievements are commendable, expanding his outreach to interdisciplinary collaborations could enhance the applicability of his findings. Increasing engagement in public awareness and education on the significance of his research in medicinal chemistry could also strengthen his influence beyond academic circles. Further diversification of research themes might attract funding and foster novel explorations in related areas.
Education
Dr. Negi completed his B.Sc. in Physics, Chemistry, and Mathematics from Lucknow Christian Degree College, University of Lucknow, in 1989. He excelled academically, earning his M.Sc. in Chemistry with First Rank from the same university in 1991. He further pursued a Ph.D. in Medicinal Chemistry at CSIR-Central Drug Research Institute, obtaining his degree in 1999. His educational journey includes significant research experiences, starting as a Scientist at ICAR-Indian Grassland and Fodder Research Institute in 1995. Dr. Negi has continuously advanced his knowledge and expertise through various fellowships, including prestigious opportunities at renowned international institutions, shaping his specialization in organic and natural product chemistry.
Experience
Dr. Arvind Singh Negi boasts over 25 years of research experience in the field of medicinal chemistry. He began his career as a Scientist at ICAR-Indian Grassland and Fodder Research Institute in 1995, moving on to join CSIR-CIMAP in 2000. Over the years, he has progressed through various ranks, becoming a Chief Scientist in 2018. His extensive experience encompasses research and development of natural product-based pharmaceuticals, focusing on cancer therapeutics and organic synthesis. Dr. Negi has also supervised multiple Ph.D. theses and collaborated with national and international researchers, contributing to over 100 research publications. His leadership in the Phytochemistry Division has fostered innovative research projects, enhancing the institute’s reputation in medicinal plant research.
Awards and Honors
Dr. Negi’s exemplary contributions to science have been recognized through numerous awards and honors. He was awarded the CSIR-JRF and Lectureship in 1991, followed by the ICAR Assistant Professorship in 1994. His research has earned him the Bioorganic & Medicinal Chemistry Most Cited Paper Award three times (2007, 2008, 2010) from Elsevier Press. He has received prestigious fellowships, including the ICS-UNIDO Fellowship in Italy (2008) and the Raman Research Fellowship in the USA (2010). Dr. Negi became a member of the National Academy of Sciences (NASI) in 2013 and was later invited to the Royal Society of Chemistry, achieving Fellow status in 2022. His recognition underscores his significant impact on medicinal chemistry and natural product research.
Research Focus
Dr. Arvind Singh Negi specializes in medicinal chemistry, with a primary focus on the development of cancer chemotherapeutics. His current research involves designing target-specific molecules to modulate microtubule dynamics, a crucial aspect of cancer treatment. By harnessing the therapeutic potential of natural products, he investigates plant-based compounds that exhibit anticancer properties. His work encompasses extensive studies on the chemical and biological profiles of medicinal plants, contributing to the discovery of novel anticancer agents. Dr. Negi’s innovative approaches aim to bridge the gap between traditional knowledge and modern scientific methodologies, making significant strides in the field of phytochemistry. His research not only enhances our understanding of cancer therapeutics but also promotes the exploration of sustainable and effective treatments derived from nature.
Publication Top Notes
- Plant-based anticancer molecules: A chemical and biological profile of some important leads 🌱
- Antimicrobial potential of Glycyrrhiza glabra roots 🌿
- Recent advances in plant hepatoprotectives: a chemical and biological profile of some important leads 🌿
- Current status on development of steroids as anticancer agents 💊
- Antifungal activity of Glycyrrhiza glabra extracts and its active constituent glabridin 🌿
- Gallic acid-based indanone derivatives as anticancer agents 🌿
- Synergistic anticandidal activity of pure polyphenol curcumin I in combination with azoles and polyenes generates reactive oxygen species leading to apoptosis 🌿
- Natural antitubulin agents: Importance of 3, 4, 5-trimethoxyphenyl fragment 🌱
- Synthesis of chalcone derivatives on steroidal framework and their anticancer activities 💊
- Synthesis of 1-(3′,4′,5′-trimethoxy) phenyl naphtho[2,1b]furan as a novel anticancer agent 🌱
- Plant isoquinoline alkaloids: Advances in the chemistry and biology of berberine 🌱
- An insight into medicinal chemistry of anticancer quinoxalines 💊
- Antitubercular potential of some semisynthetic analogues of phytol 🌱
- Defective in cuticular ridges (DCR) of Arabidopsis thaliana, a gene associated with surface cutin formation, encodes a soluble diacylglycerol acyltransferase 🌱
- Nutritive evaluation of some nitrogen and non-nitrogen fixing multipurpose tree species 🌳
- Antiproliferative and antioxidant activities of Juglans regia fruit extracts 🌰
- Synthesis of pharmacologically important naphthoquinones and anticancer activity of 2-benzyllawsone through DNA topoisomerase-II inhibition 💊
- A bioactive labdane diterpenoid from Curcuma amada and its semisynthetic analogues as antitubercular agents 🌿
- Anticancer activity and toxicity profiles of 2-benzylidene indanone lead molecule 💊
- A promising anticancer and antimalarial component from the leaves of Bidens pilosa 🌿
Conclusion
Dr. Arvind Singh Negi is an exemplary candidate for the Outstanding Scientist Award. His pioneering work in medicinal chemistry, along with his dedication to advancing cancer therapeutics through innovative research, positions him as a leader in the field. With strategic enhancements in collaboration and outreach, his impact could extend even further, benefiting both scientific communities and public health.