Gökçe Karaotmarlı Güven | Cancer Cell Biology | Best Research Article Award

Mrs. Gökçe Karaotmarlı Güven | Cancer Cell Biology | Best Research Article Award

Mrs. Gökçe Karaotmarlı Güven | Biruni University, Faculty of Pharmacy | Turkey

Gökçe Karaotmarlı Güven, born on July 22, 1996, is a dynamic and passionate Research Assistant with a strong academic foundation in pharmaceutical sciences. She earned her Bachelor’s degree from Biruni University, Faculty of Pharmacy in 2020, and is currently pursuing her Ph.D. in Pharmaceutical Technology at Health Sciences University, where she is deeply involved in cutting-edge nanomedicine research. Her expertise lies in carbon quantum dots, drug delivery systems, and bio-nanotechnology. Gökçe has collaborated on innovative research projects and has contributed significantly to the scientific community through high-impact publications and patent filings. Her interdisciplinary research combines pharmaceutical technology, nanoscience, and biotechnology, aiming to advance targeted drug delivery for diseases like cancer. She is recognized for her analytical mindset, scientific curiosity, and collaborative spirit, which fuel her aspiration to become a leading figure in pharmaceutical nanotechnology. Gökçe continues to explore novel therapeutic technologies to address some of the most pressing challenges in modern medicine.

orcid

✅ Strengths for the Award:

  1. Innovative Research:
    Gökçe has demonstrated a clear focus on high-impact, novel research—especially with her work on boron-doped carbon quantum dots for targeted drug delivery and cancer therapy. Her work represents a pioneering intersection of nanotechnology and pharmaceutical sciences.

  2. High-Quality Publications:
    She has published in internationally respected journals such as Pharmaceuticals, Applied Sciences, and Journal of Research in Pharmacy. The topics she covers—quantum drug development, phytochemical-based wound therapies, and ocular drug delivery—are timely and significant to global health.

  3. Patent Contributions:
    With three patent applications (2024–2025), her research is not only academic but also translational and innovation-driven, showing real-world applicability—a vital criterion for research excellence awards.

  4. Collaborative and Interdisciplinary Work:
    Gökçe has worked with both national and international teams, indicating strong teamwork, adaptability, and leadership in multidisciplinary settings.

🔄 Areas for Improvement:

  1. Broader Publication Indexing:
    Although her work is high quality, more publications in top-tier Q1 journals indexed by PubMed/Scopus/Web of Science would further validate her research’s global impact and improve her visibility.

  2. Post-Doctoral Research Exposure:
    Expanding her research experience internationally through postdoctoral fellowships or collaborations abroad could enhance the depth of her academic profile and increase her competitiveness for global-level research awards.

  3. Greater Conference Participation:
    Active presentation in international conferences, symposiums, or research summits would broaden her academic reach and help disseminate her innovations to a larger audience.

🎓 Education:

Gökçe Karaotmarlı Güven’s educational background reflects her commitment to pharmaceutical sciences and innovation. She obtained her Bachelor’s degree from the Faculty of Pharmacy at Biruni University in 2020, where she developed a solid understanding of pharmaceutical chemistry and drug formulation. Currently, she is pursuing a Ph.D. in Pharmaceutical Technology at the Health Sciences University, Hamidiye Faculty of Pharmacy. Her doctoral research is focused on the synthesis, biodistribution, and pharmacokinetics of boron-doped carbon quantum dots—highly advanced nanomaterials with potential applications in drug delivery and cancer therapy. Under the mentorship of Prof. Dr. Neslihan Üstündağ Okur and co-advisor Prof. Dr. İsmail Tuncer Değim, she is conducting high-level research that blends nanotechnology with targeted therapeutic systems. Her academic training is complemented by active involvement in laboratory-based innovation and scholarly writing, making her well-prepared for an impactful career in both academia and the pharmaceutical industry.

💼 Experience:

Gökçe Karaotmarlı Güven is currently working as a Research Assistant at Health Sciences University, where she contributes to numerous multidisciplinary projects in the field of pharmaceutical nanotechnology. Her professional journey began with laboratory internships and academic projects during her undergraduate years, focusing on drug formulation and ocular drug delivery systems. During her Ph.D., she has played a pivotal role in designing and characterizing nanocarriers for targeted drug delivery, particularly in cancer treatment and wound healing. Her hands-on experience includes formulation science, analytical instrumentation, preclinical biodistribution studies, and in vitro pharmacokinetics. Gökçe has been involved in patentable inventions and has co-authored multiple high-impact journal articles in international journals. Her collaborations span across Turkish and international institutions, showcasing her ability to work in team-based research environments. Her strengths lie in research design, scientific communication, and a deep understanding of advanced drug delivery systems, making her an asset to any pharmaceutical research team.

🔬 Research Focus:

Gökçe Karaotmarlı Güven’s research centers on the intersection of nanotechnology and pharmaceutical sciences, particularly in the development of carbon quantum dots (CQDs) for targeted drug delivery. Her doctoral thesis involves the preparation, biodistribution, and pharmacokinetic evaluation of boron-doped carbon quantum dots and composite carbon quantum dots, aimed at enhancing drug delivery efficiency in cancer treatment. Her interests extend to quantum drug technologies, ocular drug delivery systems, and hydrogel formulations containing bioactive molecules. Through her collaborative research, she explores the role of nanoformulations in wound healing, antimicrobial applications, and personalized medicine. Gökçe is particularly passionate about applying nanotechnology to solve real-world therapeutic challenges, especially in cancer and ophthalmic care. Her work is informed by a multidisciplinary approach, blending pharmaceutical chemistry, nanoscience, and biotechnology. Her research is innovative, patentable, and addresses unmet needs in the current pharmaceutical landscape, positioning her as a rising scholar in next-generation drug delivery systems.

📚 Publications Top Notes:

  1. 🧬 Quantum Drugs (Q-Drugs): A New Discovery and Taboo Breaking Approach; Producing Carbon Quantum Dots from Drug MoleculesPharmaceuticals, 2025-05-22

  2. 🌿 Nanoformulations Loaded with Phytochemicals for Combating Wound Infections and Promoting Wound HealingApplied Sciences, 2025-05-12

  3. 👁️ In situ gels loaded with naringin as ocular drug delivery carriers; development and preliminary characterizationJournal of Research in Pharmacy, 2024

  4. 💧 Preparation and characterization of carbopol based hydrogels containing dexpanthenolAnkara Universitesi Eczacilik Fakultesi Dergisi, 2023-06-12

📝 Conclusion:

Gökçe Karaotmarlı Güven stands out as a highly promising young researcher whose work is innovative, scientifically sound, and application-focused. Her contributions to the development of novel drug delivery systems, particularly through carbon quantum dots and nanomedicine strategies, mark her as a deserving candidate for the Best Research Article Award.

Her work aligns with the values such awards seek to recognize: originality, relevance, translational impact, and collaborative strength. With continued growth in international exposure and expanded publication reach, she will not only be a worthy recipient now but also an influential leader in pharmaceutical nanotechnology in the future.

Dalia Saleh | Cancer Cell Biology | Innovative Research Award

Prof . Dalia Saleh | Cancer Cell Biology | Innovative Research Award

Prof . Dalia Saleh | National Research Centre | Egypt

Dr. Dalia Osama Abd El Fattah Saleh is a distinguished pharmacologist with over two decades of experience in experimental pharmacology and drug development. She holds a Ph.D. in Pharmacology from Cairo University and currently serves as a Professor at the National Research Centre in Cairo, Egypt. Dr. Saleh has contributed to numerous high-impact scientific journals and has led pioneering work in the areas of metabolic disorders, drug safety, and vascular pharmacology. Her multidisciplinary collaborations and continuous professional development from institutions like King’s College London demonstrate her dedication to excellence in research and education. She is also recognized for her commitment to academic instruction and quality assurance, having served as a Quality Assurance Director. Her work bridges scientific discovery and real-world therapeutic applications, making her a strong candidate for innovation-focused research awards.

publication profile:

scopus

Strengths for the Award:

  1. Robust Academic Background:
    Dr. Saleh holds a Ph.D. in Pharmacology from Cairo University and has a long-standing academic and research career in pharmacology and drug development. Her doctoral and master’s theses reflect a strong foundation in vascular pharmacology, metabolic disorders, and endocrine influence—fields of enduring relevance.

  2. Consistent Research Productivity:
    Her recent publication record (2022–2024) is prolific and impactful, with studies published in high-visibility journals such as Scientific Reports, Biochemistry and Cell Biology, Naunyn-Schmiedeberg’s Archives of Pharmacology, and Environmental Science and Pollution Research. Her work covers cutting-edge pharmacological topics, including:

    • AMPK/mTOR signaling pathways,

    • Neuroprotection and anti-inflammatory mechanisms,

    • Herbal and synthetic compounds in disease modulation,

    • Hepatic encephalopathy, diabetic nephropathy, and cystitis models.

  3. Interdisciplinary and Translational Approach:
    Dr. Saleh bridges basic pharmacological research with clinical relevance. Her investigations into molecular pathways (e.g., NF-κB, PI3K/Akt, SIRT-1) are grounded in disease models, thus demonstrating translational potential. Her inclusion of both natural and synthetic agents further adds diversity and innovation to her research.

  4. Capacity Building and International Exposure:
    She has participated in Continuing Professional Development modules at King’s College London, emphasizing drug safety, statistics, and ethics—key areas in modern drug development. This international engagement underscores her commitment to staying updated and aligned with global standards.

  5. Institutional Contribution and Leadership:
    As a Professor and former Quality Assurance Director at the National Research Centre (NRC), she has contributed to institutional excellence, including achieving ISO 9001/2008 certification. These roles reflect her leadership, organizational, and strategic planning skills.

Areas for Improvement:

  1. Principal Investigator Leadership:
    While her name appears consistently in multi-author studies, further highlighting her role as the principal investigator (PI) or corresponding author could strengthen her case for innovation leadership.

  2. Patents or Product Development:
    There is no mention of patents or direct product development based on her findings. Translating research into tangible therapeutics or clinical trials would significantly elevate her eligibility for innovation-specific awards.

  3. Global Collaborations and Grants:
    Although she has participated in international seminars, active global collaborations or leading major international grants/projects would further establish her as a global innovator.

  4. Public/Industry Impact:
    While the academic impact is strong, showcasing industry partnerships or policy-level influence (e.g., contributions to clinical guidelines or regulatory science) would align more directly with innovation awards that emphasize practical application.

🎓 Education Summary :

Dr. Dalia Saleh completed her higher education at Cairo University’s Faculty of Pharmacy, where she earned her Master of Science in Pharmacology in 2009 and Doctor of Philosophy in Pharmacology in 2012. Her M.Sc. thesis focused on the vascular and biochemical effects of rosiglitazone in diabetic rats, reflecting early interests in metabolic pharmacology. Her Ph.D. expanded on this foundation by exploring estrogen’s potential role in managing vascular changes related to insulin resistance. Both theses demonstrated robust experimental designs and contributed new insights into the interplay between hormonal and metabolic pathways in disease models. Dr. Saleh has since built on this academic background with advanced training in clinical drug development, safety, and biostatistics at King’s College London in 2023, indicating a continued commitment to integrating modern pharmaceutical science and translational research into her academic portfolio. This rich educational foundation underpins her success as a researcher and educator.

🔬 Research Focus :

Dr. Saleh’s research focuses on experimental pharmacology, with a special interest in metabolic diseases, drug-induced toxicities, inflammation, and vascular pharmacology. Her studies frequently involve animal models to investigate the mechanisms of drug action and to evaluate the protective or therapeutic roles of natural products and synthetic compounds. A recurring theme in her work is exploring the modulation of signaling pathways like AMPK, NF-κB, PI3K/mTOR, and Nrf2 in the context of oxidative stress, inflammation, and cellular apoptosis. She has also studied the role of hormonal influences in disease models, such as estrogen’s effect on insulin resistance. Her research employs modern analytical techniques and integrates molecular biology with pharmacodynamics to derive mechanistic insights. This strong focus on mechanistic pharmacology enhances her work’s relevance in drug development, particularly for conditions such as diabetic complications, hepatic encephalopathy, nephropathy, and chemotherapy-induced toxicities.

📚 Publications Top Note:

  1. 🧪 Eugenol alleviates acrylamide-induced testicular toxicity via AMPK/pAKT/mTOR modulationScientific Reports, 2024

  2. 🧠 Trimetazidine prevents cisplatin neuropathy through AMPK, Nrf2, and NF-κB pathwaysBiochemistry and Cell Biology, 2023

  3. 🔬 Novel chromone-thiazolopyrimidines as TNF-α, IL-6, and PGE2 inhibitorsPolycyclic Aromatic Compounds, 2023

  4. 🚽 Chrysin protects against cyclophosphamide-induced hemorrhagic cystitis via anti-inflammatory signalingChemico-Biological Interactions, 2023

  5. 🧃 Linagliptin & L-arginine synergy in gastric hyperacidity via EP4 receptor upregulationNaunyn-Schmiedeberg’s Archives of Pharmacology, 2023

  6. 🧠 L-arginine reduces thioacetamide-induced hepatic encephalopathy via NF-κB downregulationEnvironmental Science and Pollution Research, 2023

  7. 🌿 Calotropis procera seed oil shows anti-inflammatory and antiparasitic activityArabian Journal of Chemistry, 2022

  8. 🛡️ Olmesartan mitigates diabetic nephropathy via AGE/PKC and TLR4/SIRT-1 pathwaysEuropean Journal of Pharmacology, 2022

  9. 🍃 Plumbago species show anti-fibrotic effects in liver fibrosis rat modelsScientific Reports, 2022

  10. 🫀 Omega-3 combats doxorubicin-induced liver toxicity via Nrf2/PI3K/Akt signalingPending Publication

Conclusion:

Dr. Dalia O. Saleh presents a strong candidacy for the Research for Innovative Research Award, particularly due to her sustained publication record, mechanistic depth in pharmacology, and commitment to professional development and institutional excellence. Her work spans innovative mechanistic explorations and novel therapeutic evaluations, showing real promise in addressing current pharmacological challenges.

Dominique Heymann | Cancer Cell Biology | Best Researcher Award

Prof. Dr. Dominique Heymann | Cancer Cell Biology | Best Researcher Award

Prof. Dr. Dominique Heymann , Nantes Université, CNRS, Institut de Cancérologie de l”Ouest , France

Professor Dominique Heymann is a highly esteemed academic and clinician, specializing in histology, embryology, and oncology. He is a Professor at Nantes University, France, and a Hospital Practitioner at the ICO Cancer Centre. With a wealth of experience in bone oncology and cancer research, he is also an Honorary Professor at the University of Sheffield, UK. His expertise spans from cell biology to immunology and biochemistry, and he is dedicated to advancing cancer research, particularly in the field of bone tumors and osteosarcoma. With numerous publications to his name and contributions to the global scientific community, Professor Heymann is recognized for his groundbreaking work in cell signaling and tumor progression. He is a valued researcher in the oncology community, with a strong focus on developing innovative therapies for cancer treatment.

Publication Profile:

Google Scholar

Strengths for the Award:

Professor Dominique Heymann is a distinguished figure in the field of oncology, particularly bone oncology, with a strong focus on the molecular mechanisms of bone tumors like osteosarcoma. His academic and clinical roles at the University of Nantes and the ICO Cancer Centre underscore his leadership in research and patient care. He has contributed significantly to understanding tumor biology, bone remodeling, and regenerative medicine, making him a highly respected expert in these fields. His research addresses crucial topics such as circulating tumor cells, targeted therapies, and the development of new anticancer agents, all of which are of immense value to advancing cancer treatment. With multiple publications in prestigious journals, including studies on novel therapies and molecular pathways in cancer progression, Professor Heymann has demonstrated exceptional scientific rigor. His global collaborations and recognition further establish him as a leading researcher in cancer biology and oncology.

Areas for Improvements:

Despite his numerous contributions, there are a few areas where Professor Heymann’s research could evolve. While he has made notable strides in cancer treatment and bone oncology, expanding research into more personalized medicine approaches and exploring the integration of AI and machine learning in predictive oncology could enhance the applicability of his findings. Furthermore, increasing collaborative efforts with international interdisciplinary teams could yield broader insights, especially in rare cancers and metastasis research. Developing a more extensive outreach to clinical trials and collaborations in broader regions may also allow for faster translation of his research into practice.

Education:

Professor Heymann began his academic journey at Paris VII University, where he earned a Master’s degree in Cell Biology in 1991. His PhD in Cell Biology and Immunology was completed at Nantes University in 1995, a pivotal moment in his career. Further expanding his knowledge, he pursued research management abilities and a deeper focus on Biochemistry and Cell Biology at Nantes University in 1998. He also received specialized certification in Histology from Nantes University in 1999 and later completed the required authorizations for animal experimentation in 2003 and 2016. Throughout his academic career, Professor Heymann has continually updated his qualifications, ensuring his expertise remains at the cutting edge of medical and biological sciences. His academic foundation has underpinned his significant contributions to cancer research, with a strong emphasis on bone oncology and regenerative medicine.

Experience:

Professor Dominique Heymann has an extensive and diverse career spanning several decades in both academic and clinical settings. Currently, he serves as a Professor of Histology/Embryology at Nantes University and as a Hospital Practitioner at the ICO Cancer Centre, where he is instrumental in patient care and research. His professional trajectory includes significant roles in oncology, particularly focused on bone tumors, osteosarcoma, and regenerative medicine. As an Honorary Professor at the University of Sheffield, he extends his influence beyond France, fostering international collaboration in cancer research. Professor Heymann has been a prominent figure in multiple research projects, having managed and contributed to groundbreaking studies. His expertise in cancer biology, combined with his academic roles, has allowed him to mentor students and researchers, shaping the next generation of scientists. His dual role in academia and clinical practice makes him a leading figure in both spheres.

Awards and Honors:

Professor Dominique Heymann’s career is adorned with numerous accolades and honors. As a tenured professor at the University of Nantes, he has received recognition for his contributions to histology, embryology, and oncology. He was appointed as an Honorary Professor in Bone Oncology at the University of Sheffield, UK, an esteemed acknowledgment of his expertise in the field. His work in cancer research, particularly related to bone tumors, has earned him international recognition, and his published studies continue to be highly regarded in scientific journals. Additionally, Professor Heymann has contributed significantly to the understanding of osteosarcoma and bone regeneration, which has earned him awards from academic and clinical societies. His continuous impact in advancing the field through groundbreaking research, leadership in clinical oncology, and educational contributions has made him a highly respected figure in the medical and scientific communities.

Research Focus:

Professor Dominique Heymann’s research is focused on cancer, particularly bone tumors such as osteosarcoma, and the molecular mechanisms involved in bone regeneration. His work primarily investigates the signaling pathways that control bone remodeling, the interactions between tumor cells and the microenvironment, and the role of immune responses in bone diseases. One of his key research interests is the development of targeted therapies to combat cancer progression, with a special emphasis on novel anticancer agents, including glycosaminoglycan-mimetic compounds derived from marine bacterial exopolysaccharides. In addition, Professor Heymann is dedicated to studying the role of circulating tumor cells as predictive markers for drug resistance and tumor progression. His expertise also includes stem cell therapies, autophagy in osteoblasts, and the potential for therapeutic applications in bone repair and regeneration. His research aims to improve patient outcomes through innovative approaches in cancer treatment and bone health.

Publications Top Notes:

  • Heymann D, Muñoz-Garcia J, Babuty A, et al. A new promising anticancer agent: a glycosaminoglycan-mimetic derived from the marine bacterial infernan exopolysaccharide. Int J Biol Macromol. (in press) 🧬

  • Jacquot P, Muñoz-Garcia J, Léger A, et al. A multispecific checkpoint inhibitor Nanofitin with a fast tumor accumulation property and antitumor activity in immune competent mice. Biomolecules. (in press) 🔬

  • Yadav P, Heymann D, Prasad RN. Circulating tumor cells: a predictive marker for drug resistance and tumor progression. Front Oncol. (in press) 🔬

  • Muñoz-Garcia J, et al. Interleukin-34 orchestrates bone formation through its binding to Bone Morphogenic Proteins. Theranostics. 2025; 15(7):3185-3202. 🦴

  • Young RJ, et al. CIRCUS: CIRCUlating tumor cells in soft tissue Sarcoma – a short report. Cancer Drug Resist. 2022; 4:51. 💉

  • Oliver L, et al. Transcriptional landscape of the interaction of human mesenchymal stem cells with glioblastoma in bioprinted co-cultures. Stem Cell Res Ther. 2024; 15(1):424. 🧫

  • Cordova LA, et al. Why are osteoporosis patients treated with antiresorptive therapies considered like oncology patients regarding their oral health care? Osteoporos Int. 2024; 35(9):1677-1678. 🦷

  • Childs A, et al. A prospective observational cohort study for newly diagnosed patients in the UK: ICONIC study initial results. Cancers (Basel). 2024; 16(13):2351. 📊

  • Rey V, et al. A personalized medicine approach identifies enasidenib as an efficient treatment for IDH2 mutant chondrosarcoma. EBioMedicine. 2024; 102:105090. 🧬

  • Jubelin C, et al. Identification of MCM4 and PKRDC as new regulators of osteosarcoma cell dormancy based on 3D cultures. BBA Mol Cell Res. 2024; 1871:119660. 🧪

Conclusion:

Professor Dominique Heymann’s expertise in oncology, histology, and embryology positions him as an outstanding candidate for the Research for Best Researcher Award. His achievements in cancer research, particularly in bone tumors, and his contributions to advancing the understanding of tumor biology make him an exemplary figure. While there are areas to expand in terms of interdisciplinary collaborations and technological integration, his exceptional body of work and his dedication to both academic excellence and clinical practice make him a deserving candidate for this prestigious award.

Weikuan Gu | Cancer Cell Biology | Best Researcher Award

Prof. Weikuan Gu | Cancer Cell Biology | Best Researcher Award

Prof. Weikuan Gu , UTHSC , United States

Weikuan Gu is a Professor at the University of Tennessee Health Science Center, specializing in biomedical research with a focus on disease modeling, genetic factors influencing health, and drug efficacy. After earning his MS and Ph.D. from Cornell University, he worked on eye diseases, osteoporosis, and genetics before joining UTHSC in 2002. His contributions in AI applications for biomedical research are noteworthy. He has developed the Principal Law of Lifespan (PLOSP) theory and has been recognized for his leadership in various international collaborative projects. With a significant role in numerous NIH-funded studies, his research continues to push boundaries in understanding disease mechanisms and therapeutics.

Publication Profile: 

Google Scholar

Strengths for the Award:

  1. Extensive Research Experience: Professor Weikuan Gu has over two decades of experience in biomedical research, demonstrating expertise across a wide array of disease models, drug efficacy, and genetic factors influencing health. His work spans a variety of high-impact fields such as ophthalmology, osteoporosis, arthritis, and genomics, showcasing a strong commitment to advancing understanding in multiple medical domains.

  2. Innovative Research Leadership: Professor Gu has been instrumental in leading and contributing to groundbreaking research, including his development of the Principal Law of Lifespan (PLOSP). His ability to innovate, especially in applying AI to biomedical research, positions him at the forefront of cutting-edge science and technology.

  3. Funded Projects & International Collaborations: He has secured substantial funding for his projects, totaling millions of dollars, and has led many high-profile international collaborations. This speaks to the global relevance and potential impact of his work, as well as his ability to manage large-scale research initiatives.

  4. Research Output and Citations: With 175 published scientific papers and multiple accepted articles in prestigious journals such as Cancer Letters and Ecotoxicology and Environmental Safety, his research continues to have a significant impact on the scientific community. His most recent work on AI applications and its implications for public health and disease diagnosis are particularly notable.

  5. Contribution to Education and Training: Professor Gu has played a key role in training future researchers, as evident from his leadership in the Gene Discovery Microarray Core at UTHSC and his involvement in several research education collaborations internationally. His contributions to scientific training are essential for developing the next generation of researchers.

Areas for Improvement:

  1. Broader Public Outreach: While Professor Gu’s research has made significant contributions to the scientific community, there is room to enhance the visibility of his work among broader audiences, including policy makers, healthcare professionals, and the general public. Public engagement with his AI-focused research could improve the real-world application of his findings, especially in public health.

  2. Interdisciplinary Collaboration: Although his collaborations are already diverse, fostering even more interdisciplinary collaborations with experts from areas like data science, engineering, and social sciences could expand the scope of his research, especially in areas like AI and healthcare.

Education:

Dr. Gu completed his MS and Ph.D. from Cornell University, where he specialized in molecular genetics. His academic journey focused on genetic disorders, particularly in disease modeling and understanding complex genetic mechanisms. His research provided foundational insights into eye diseases and osteoporosis, leading to his early work at Loma Linda University and later at the University of Tennessee Health Science Center. His vast academic knowledge enables him to merge genetic research with cutting-edge technologies, including AI applications in biomedical research, paving the way for transformative healthcare solutions.

Experience:

Dr. Weikuan Gu has a rich career that spans over two decades in biomedical research. His early work at Loma Linda University involved osteoporosis and genetic studies in human and mouse models. Since joining the University of Tennessee Health Science Center in 2002, his research expanded to disease modeling, drug efficacy, and the role of genetics in health. He has been a principal investigator and co-investigator in numerous NIH-funded projects, specializing in genetic factors influencing diseases like osteoarthritis, fibrotic diseases, and stroke. Additionally, he is involved in AI-based research, advancing the integration of AI in biomedical research methodologies.

Research Focus:

Dr. Weikuan Gu’s research is centered on understanding disease mechanisms and therapeutic strategies, with a focus on genetic and molecular factors. His work spans glaucoma therapy, fibrotic diseases, and AI in biomedical research. He is the lead on various NIH-funded projects, investigating genetic regulation in conditions like osteoarthritis and stroke. One of his innovative contributions is the Principal Law of Lifespan (PLOSP), a theory aimed at understanding the aging process. His multidisciplinary approach, combining traditional genetic research with modern technologies such as AI, positions him at the forefront of cutting-edge biomedical research.

Publications Top Notes:

  1. “Generating Research Hypotheses to Overcome Key Challenges in the Early Diagnosis of Colorectal Cancer – Future Application of AI” 🧬
  2. “Alarm: Retracted Articles on Cancer Imaging Are Not Only Continuously Cited by Publications but Also Used by ChatGPT to Answer Questions” 💻
  3. “Evaluation of the Potential Value of Artificial Intelligence (AI) in Public Health Using Fluoride Intake as the Example” 🤖

Conclusion:

Professor Weikuan Gu is an exceptionally qualified candidate for the Best Researcher Award. His extensive experience, leadership in innovative research, impressive body of published work, and commitment to advancing both scientific discovery and education make him a standout candidate. While there are opportunities for further enhancing public outreach and expanding interdisciplinary collaborations, his ongoing contributions to AI in biomedicine and genetic research firmly establish him as a leader in his field.

Chang Feng | Cancer Cell Biology | Best Researcher Award

Dr. Chang Feng | Cancer Cell Biology | Best Researcher Award

Dr. Chang Feng , Shanghai University , China

Chang Feng is a distinguished researcher in the fields of tumor molecular diagnosis, biosensing, and intelligent DNA. Born in Shanghai, China, on January 1, 1988, Chang Feng pursued a rigorous academic journey, completing his Ph.D. at Nanjing University (2015-2019) after earning his M.D. from Shanghai University (2012-2015). He is currently a lecturer at Shanghai University since 2019. Feng has contributed significantly to scientific advancements in cancer diagnostics, molecular biosensors, and cutting-edge DNA research. His works often involve the development of innovative detection techniques and the creation of novel DNA-based diagnostic systems. Feng has a collaborative approach, working with multiple researchers to achieve groundbreaking results. His publications in prestigious journals highlight his expertise in developing biosensors, RNA origami, and catalytic DNAzymes for biomedical applications.

Publication Profile: 

Scopus

Strengths for the Award:

Chang Feng’s research is exceptional and well-suited for the Best Researcher Award. His expertise spans across tumor molecular diagnosis, biosensor development, and intelligent DNA systems. His contributions to cancer diagnostics, bioimaging, and biosensing technologies are groundbreaking. Feng has published several high-impact articles in leading journals, demonstrating significant advancements in DNAzymes, electrochemical biosensing, and RNA origami. His work in designing innovative DNA-based diagnostic platforms and cancer therapies reflects his ability to integrate chemistry, biology, and engineering, providing novel solutions for clinical applications. Feng’s interdisciplinary approach and leadership in the field have earned him numerous collaborations with researchers and institutions globally, further enhancing his credibility as a top-tier researcher.

Areas for Improvements:

While Feng has made remarkable contributions to scientific research, one area for improvement is expanding his focus to more clinical applications of his findings. Commercializing his biosensing technologies for real-world healthcare implementation would increase the practical impact of his work. Additionally, improving outreach through public science communication could help raise awareness of his advancements and engage a broader audience.

Education:

Chang Feng received his M.D. from Shanghai University in 2015, where he developed a strong foundation in molecular biology, diagnostics, and bioengineering. His doctoral journey continued at Nanjing University (2015-2019), where he obtained his Ph.D. focusing on tumor molecular diagnosis and biosensing technologies. During his time at Nanjing University, Feng’s research concentrated on the development of DNA-based biosensors and new methodologies for cancer detection. His education at these esteemed institutions provided him with the technical expertise necessary to pioneer groundbreaking research in the field of molecular diagnostics. Feng’s academic training involved rigorous coursework in molecular biology, chemical engineering, and bioinformatics, contributing significantly to his current work in bioimaging, biosensing, and the development of intelligent DNA systems.

Experience:

Chang Feng has a strong academic and research career, currently serving as a lecturer at Shanghai University since 2019. Prior to his current role, he earned his Ph.D. at Nanjing University (2015-2019) and M.D. from Shanghai University (2012-2015). Throughout his career, Feng has collaborated with leading researchers, contributing to the development of innovative biosensing technologies and cancer diagnostics. His work includes advancing DNA-based biosensors, DNAzyme probes, and other cutting-edge diagnostic tools. As a lecturer, Feng mentors graduate students and participates in academic teaching and research projects. He has been involved in several collaborative publications that have furthered the field of molecular biosensors, focusing on intelligent DNA-based systems and tumor detection methodologies. Feng’s research experience combines theoretical knowledge with practical applications, making him a recognized figure in the field of biosensor research and molecular diagnostics.

Research Focus:

Chang Feng’s primary research focus lies in tumor molecular diagnosis, biosensor development, and intelligent DNA systems. He is particularly interested in advancing technologies for cancer detection through the application of molecular biosensors, bioimaging, and intelligent DNA devices. His research explores the use of DNAzymes, catalytic DNA molecules, and RNA origami for targeted molecular detection, with a focus on enhancing the sensitivity and specificity of cancer diagnostics. Feng’s work also investigates the use of biosensors for the detection of small molecules, leveraging innovative electrochemical and fluorescence-based platforms. His interdisciplinary approach combines elements of chemistry, biology, and engineering to create advanced diagnostic systems with potential clinical applications. Feng is dedicated to improving the efficiency of diagnostic tools and is committed to developing more accurate and faster methods for early cancer detection and molecular analysis.

Publications Top Notes:

  1. Single-cell analysis of highly metastatic circulating tumor cells by combining a self-folding induced release reaction with a cell capture microchip 🧬🔬 (Anal. Chem., 2021)
  2. Hierarchical biomarkers detection via a universal polydopamine probe catalyzed by a hexagonal star-nanostructured DNAzyme 🔬🧪 (Sensor. Actuat. B-Chem., 2022)
  3. Construction of a ternary complex based DNA logic nanomachine for a highly accurate imaging analysis of cancer cells 🧬💡 (ACS Sens., 2020)
  4. Lantern-shaped flexible RNA origami for Smad4 mRNA delivery and growth suppression of colorectal cancer 🧬🦠 (Nat. Commun., 2023)
  5. Liquid-colloid-solid modular assembly for three-dimensional electrochemical biosensing of small molecules 💧⚡ (Biosens. Bioelectron., 2024)
  6. Dual-targets binding protection mediated rolling circle transcription with tandem fluorescent RNA aptamers for label-free detection of liver cancer biomarkers 🧬🦠 (Sensor. Actuat. B-Chem., 2024)
  7. Cell-Free Biosensing Genetic Circuit Coupled with Ribozyme Cleavage Reaction for Rapid and Sensitive Detection of Small Molecules 🧬⚡ (ACS Synth. Biol., 2023)
  8. A portable and partitioned DNA hydrogel chip for multitarget detection 💧🧬 (Lab Chip., 2023)

Conclusion:

Chang Feng’s research in tumor molecular diagnostics, biosensors, and intelligent DNA is truly cutting-edge. His scientific rigor, collaboration with top researchers, and groundbreaking discoveries in cancer detection and biosensing technologies make him a deserving candidate for the Best Researcher Award. By continuing to bridge the gap between laboratory research and clinical applications, Feng will likely have an even greater impact in advancing medical diagnostics and therapeutic strategies.

Peter du Plessis | Cancer Cell Biology | Best Researcher Award

Mr. Peter du Plessis | Cancer Cell Biology | Best Researcher Award

Mr. Peter du Plessis , iThemba LABS , South Africa

Peter Clark du Plessis is an accomplished professional with a robust background in radiotherapy and oncology. His career spans over two decades, starting as a Radiation Therapist and Researcher at iThemba LABS since 2006. He is dedicated to both teaching and research, fostering critical thinking and academic growth among students. Apart from his academic contributions, Peter is passionate about mentoring and enjoys long walks and playing chess in his spare time. With a string of accolades, including Director’s Special Awards in 2012 and 2014, he consistently demonstrates excellence in his field. He is committed to inspiring the next generation of healthcare professionals through hands-on experience, leadership, and a deep passion for his profession.

Publication Profile:

Orcid

Strengths for the Award:

Peter Clark du Plessis exemplifies the qualities of a leading researcher in radiotherapy and oncology, making him highly suitable for the Best Researcher Award. His career spans over two decades, showcasing not only professional expertise but a commitment to advancing cancer treatment through research. Peter has a wealth of hands-on experience, holding key roles at iThemba LABS, where his research continues to shape the field of hypofractionated radiotherapy for breast and prostate cancers. His mentorship and dedication to teaching further highlight his influence on future healthcare professionals. Additionally, his accolades, including two Director’s Special Awards, demonstrate a history of excellence and recognition from peers in his field. Peter’s work also bridges research and practice, contributing significantly to improving radiotherapy techniques for cancer patients.

Areas for Improvement:

Although Peter’s achievements are commendable, his research could benefit from increased international collaborations to diversify research perspectives and data. Further partnerships with global research institutions could strengthen the practical impact of his findings, particularly in addressing diverse patient needs in different populations. Expanding his visibility in clinical trials and engaging with other healthcare sectors could further solidify his standing as a leader in oncology research.

Education (150 words):

Peter Clark du Plessis is currently pursuing a Doctorate in Radiography (DRRAD) at the Durban University of Technology, focusing on the hypofractionated radiotherapy for breast and prostate cancer (2022-2024). He holds a Master’s degree in Radiography from the Cape Peninsula University of Technology (2017-2018), with research on radiosensitivity variations in breast cancer cells. Peter earned his Bachelor of Technology in Radiography (cum laude) in 2010 and a National Diploma in Therapeutic Radiography in 1997, both from Cape Peninsula Technikon. Additionally, he began studying Computer Science at the University of the Western Cape but did not complete the degree. His academic journey highlights his passion for improving patient care and advancing cancer treatment techniques, including his research on proton beam therapies. Peter’s ongoing research aligns with his deep commitment to enhancing oncology practices through both theoretical and practical contributions.

Experience (150 words):

Peter has a comprehensive professional history, notably as a Radiation Therapist and Researcher at iThemba LABS since 2006. Here, he has been at the forefront of advancements in radiation therapy and oncology research. Prior to that, he held positions at the Provincial Hospital in Port Elizabeth as Chief Radiation Therapist (2006) and at King Abdul-Aziz Medical City as a Mould Room Technician and Radiation Therapist (2003-2005). His teaching experience is equally impressive, having served as a lecturer and moderator at Cape Peninsula University of Technology and North West University since 2019. He has contributed to health science research courses, specifically focusing on data analysis, publications, and radiation therapy practice. His multifaceted roles in both academic and clinical settings have honed his skills in education, research, and professional development. Peter’s work has had a significant impact on radiotherapy practices and student education, particularly in the field of cancer treatment.

Awards and Honors (150 words):

Peter Clark du Plessis has received multiple awards, demonstrating his dedication and excellence in the field of radiotherapy. Most notably, he was honored with two Director’s Special Awards at iThemba LABS in 2012 and 2014, recognizing his outstanding contributions to research and clinical advancements in radiation therapy. These accolades affirm his deep commitment to both research and the application of radiotherapy techniques, specifically in cancer treatment. His work in radiotherapy has helped bridge theoretical knowledge with real-world practice, particularly in advanced cancer therapies like proton beam treatments. Peter’s passion for the field and ability to integrate research with clinical practices has been acknowledged throughout his career, making him a key figure in advancing healthcare practices. His recognition reflects the impact of his research and teaching on future healthcare professionals in the radiation therapy domain.

Research Focus (150 words):

Peter Clark du Plessis focuses on exploring and advancing radiotherapy techniques, particularly in the context of hypofractionated radiotherapy for breast and prostate cancer. His research delves into the efficacy and molecular mechanisms of these treatments, especially using proton beam therapy. With a strong foundation in radiobiology, his work investigates the variation in radiosensitivity between different cancer and normal cell types, with a particular interest in breast cancer. Peter’s research aims to improve patient outcomes by refining radiotherapy protocols, making cancer treatment more effective and personalized. His contributions are significant in bridging the gap between laboratory research and clinical practices. Peter’s goal is to inspire new approaches in cancer care by combining in vitro studies with clinical observations. His ongoing work at iThemba LABS and various academic institutions positions him at the forefront of research into innovative radiotherapy solutions.

Publications (Titles with Emojis):

  • Exploring Hypofractionated Radiotherapy Efficacy in Prostate Cancer: In Vitro Insights 🧑‍🔬📚
  • In Vitro Perspective on Hypofractionated Radiotherapy in Breast Cancer 🧑‍🔬📚
  • Immunological Changes During Space Travel: A Ground-Based Evaluation of the Impact of Neutron Dose Rate on Plasma Cytokine Levels in Human Whole Blood Cultures 🌌💉
  • The Impact of Dose Rate on DNA Double-Strand Break Formation and Repair in Human Lymphocytes Exposed to Fast Neutron Irradiation 🧬⚛️

Conclusion:

Peter Clark du Plessis is a remarkable candidate for the Best Researcher Award due to his extensive experience, impressive body of research, and dedication to advancing radiotherapy practices. His work continues to impact the field of oncology positively, offering new insights into cancer treatment methodologies. With continued growth in research collaboration and global outreach, Peter is poised to further enhance his contributions to the field of radiotherapy.

 

 

 

Ayrton Bangolo | Cancer Cell Biology | Best Researcher Award

Dr. Ayrton Bangolo | Cancer Cell Biology | Best Researcher Award

Dr. Ayrton Bangolo , Hackensack University Medical Center , United States

Ayrton I. Bangolo, MD, is an accomplished board-certified Internal Medicine physician specializing in Hematology and Oncology. He completed his MBBS (equivalent to MD) from Tianjin Medical University, China, in 2016 and is currently a Hematology and Oncology fellow at Hackensack University Medical Center, NJ. With an impressive record of research publications and contributions to several medical journals, he has a passion for advancing cancer care and the clinical aspects of various diseases. Dr. Bangolo is deeply involved in both clinical practice and research, having worked in multiple specialties and international medical settings. His expertise is enriched by his diverse experiences across different clinical environments, from hospitals in the United States to clinics in the Democratic Republic of the Congo. He holds a variety of leadership roles, demonstrating commitment to the global advancement of healthcare.

Publication Profile:

Google Scholar

Strengths for the Award:

Dr. Ayrton I. Bangolo’s exceptional contributions to the medical field make him a strong candidate for the “Best Researcher Award.” His work spans critical areas of oncology, including the impact of tumor stage and histopathology on survival outcomes in esophageal cancer, as well as his pioneering research on the gut microbiome’s role in pancreatic cancer treatment. His academic rigor is evident through his prolific research output and successful collaboration with international researchers. Additionally, Dr. Bangolo’s role as a peer reviewer for prominent medical journals underscores his expertise and respect in the medical community. His focus on racial, ethnic, and socioeconomic disparities in cancer care reflects his commitment to improving healthcare outcomes for underserved populations. Moreover, his ongoing research aims to bridge knowledge gaps in critical areas such as thyroid cancer management and gastrointestinal malignancies.

Areas for Improvement:

While Dr. Bangolo’s work is impressive, expanding his collaborative efforts to include more interdisciplinary research could enhance his scope even further. Although his focus on cancer disparities is commendable, there may be opportunities to expand his research into other areas of healthcare equity, such as mental health in cancer patients or global access to cancer treatments. Additionally, increasing involvement in clinical trials may provide real-world validation for his findings, leading to more practical applications in patient care.

Education:

Dr. Bangolo obtained his MBBS from Tianjin Medical University, Tianjin, China, in 2016, and has earned multiple certifications in the United States, including the ECFMG certification. He has successfully completed the USMLE exams, passing all steps (1, 2, and 3) on the first attempt. Dr. Bangolo is currently undergoing advanced training in Hematology and Oncology at Hackensack University Medical Center, NJ, in an ACGME-accredited fellowship program. His prior residency in Internal Medicine and a transitional year at Palisades Medical Center, North Bergen, NJ, has further honed his skills. Throughout his education, Dr. Bangolo has consistently demonstrated academic excellence and a commitment to evidence-based practice. His journey through diverse healthcare systems and international medical education reflects his dedication to global health improvement and patient-centered care.

Experience:

Dr. Bangolo has extensive clinical experience spanning multiple specialties, beginning with his externship and observership roles in Endocrinology, Nephrology, and Interventional Radiology. He served at Endocrine Associates in Louisville, KY, and worked with Dr. Hisham Alrefai in Endocrinology and Dr. Mohammed El Kheir in Nephrology. His residency in Internal Medicine at Palisades Medical Center, North Bergen, NJ, allowed him to build foundational skills in patient care and management across various medical conditions. Currently, he is completing an ACGME-accredited fellowship in Hematology and Oncology at Hackensack University Medical Center, where he continues to refine his expertise in treating complex cancer patients. Additionally, Dr. Bangolo has contributed to clinical research and presented at various academic conferences. His exposure to diverse medical environments, from the US to the Democratic Republic of the Congo, gives him a well-rounded perspective on healthcare delivery.

Awards and Honors:

Dr. Bangolo has received numerous awards and accolades, highlighting his outstanding contributions to the medical field. Among his notable recognitions is the 2nd Place for his original research poster on “Racial/Ethnic and Socioeconomic Differences in Colon Cancer Surgery Performed” during the HMH North Region Fellow/Residents Research Day. He was also involved in publishing open-access articles on significant public health issues, including the United Nations Sustainable Development Goals related to cancer treatment disparities. Dr. Bangolo’s work on ultrasound performance in the diagnosis of thyroid cancer earned recognition in the scientific community. His publications have made significant impacts, including in journals such as Breast Cancer Research and Treatment and World Journal of Gastroenterology. His consistent dedication to advancing medical knowledge, addressing healthcare disparities, and improving treatment outcomes has made him a respected figure in his field.

Research Focus:

Dr. Bangolo’s research primarily focuses on oncology, with a particular emphasis on cancer disparities, treatment outcomes, and innovative diagnostic methods. He has extensively studied the impacts of tumor stage and histopathology on survival outcomes in esophageal cancer and the influence of primary percutaneous coronary intervention on myocardial infarction outcomes. His work also includes investigating trends in thyroid cancer incidence, improving the understanding of gastrointestinal cancers, and exploring the role of the microbiome in pancreatic cancer. Dr. Bangolo is dedicated to researching the epidemiological factors that influence cancer outcomes in underserved populations, with a particular interest in racial, ethnic, and socioeconomic differences in treatment and survival. His ongoing research aims to improve treatment protocols and contribute to global cancer care, especially in resource-limited settings like the Democratic Republic of the Congo, where he has firsthand experience working.

Publications Top Notes:

  1. The Impact of Tumor Stage and Histopathology on Survival Outcomes in Esophageal Cancer Patients 📑
  2. Comprehensive Analysis of the Impact of Primary Percutaneous Coronary Intervention on Patients with ST-Segment Elevation Myocardial Infarction 💓
  3. Impact of American Thyroid Association’s Revised Cancer Management Guidelines on Thyroid Cancer Incidence Trends 📊
  4. Racial/Ethnic and Socioeconomic Differences in Colon Cancer Surgery Performed and Delayed Surgical Treatment 🎗️
  5. Ultrasound Performance Using the EU-TIRADS Score in the Diagnosis of Thyroid Cancer 🩺
  6. Epidemiologic Risk Factors for Chronic Pancreatitis and Pancreatic Ductal Adenocarcinoma 🦠
  7. Impact of Gut Microbiome in the Development and Treatment of Pancreatic Cancer 🧬
  8. Primary Cardiac Sarcoma: Clinical Characteristics and Prognostic Factors ❤️
  9. The Overall Quality of Evidence of Recommendations Surrounding Nutrition and Diet in Inflammatory Bowel Disease 🥗
  10. Outcomes of Patients with Gastrointestinal Stromal Tumors in the Past Decade 💉

Conclusion:

Dr. Ayrton I. Bangolo is undoubtedly a leading researcher in the field of oncology, with a robust academic and clinical background, significant contributions to medical literature, and a passion for addressing global healthcare disparities. His dedication to understanding complex diseases, combined with his focus on improving patient outcomes, positions him as a deserving candidate for the “Best Researcher Award.” Expanding his research to incorporate broader interdisciplinary efforts and clinical trials would further elevate his impact.

 

 

 

Huining He | Cancer Cell Biology | Best Researcher Award

Prof. Huining He | Cancer Cell Biology | Best Researcher Award

Prof. Huining He , School of Biomedical Engineering and Technology, Tianjin Medical University , China

Dr. Huining He is a prominent Professor and the Dean of the School of Biomedical Engineering and Technology at Tianjin Medical University, China. With a Ph.D. in Chemical Engineering from Tianjin University, she completed joint research at the University of Michigan. Her career spans across significant achievements in biomedical engineering, specializing in biomaterials, drug delivery systems, and cancer therapy. She has been recognized with prestigious awards, including the “Young Changjiang Scholar” and the “Tianjin Science Fund for Outstanding Young Scholars.” As an active member of various academic societies and a board member of the Asian Journal of Pharmaceutical Sciences, she fosters international collaboration and academic advancement. Her research has garnered substantial contributions to the field of biomedical engineering, with numerous patents and high-impact publications in cancer treatment and drug delivery systems.

Publication Profile:

Scopus

Strengths for the Award:

Dr. Huining He is an outstanding researcher with a strong academic and professional background. As a Professor and Dean at Tianjin Medical University, she leads the School of Biomedical Engineering and Technology with a focus on cutting-edge biomedical research, particularly in biomaterials and drug delivery systems. Her innovative work in the development of enzyme-sensitive targeted systems for gene therapy and prodrug-type macromolecular drug delivery for colon cancer is a key contribution to the field. Additionally, her leadership in several projects funded by the National Natural Science Foundation of China, particularly those targeting glioma treatment, showcases her ability to translate research into impactful clinical applications.

Dr. He’s collaboration with international and domestic institutions further enhances her research impact. She is well-regarded for pioneering novel drug delivery systems and has made notable contributions through numerous high-quality publications, which have earned her an H-index of 21 and six authorized patents. She also actively participates in academic exchanges and professional networks, serving as a member of editorial boards and scientific committees.

Areas for Improvements:

While Dr. He has made remarkable strides in biomedical engineering, there are areas where further focus could amplify her impact:

  1. Broader Clinical Application: The continued translation of her drug delivery systems into clinical settings could benefit from additional industry partnerships and clinical trials.
  2. Interdisciplinary Collaboration: Expanding her work to incorporate emerging fields such as artificial intelligence in drug delivery systems could lead to more personalized treatment solutions.
  3. Public Engagement: Increasing public awareness of her research through media and outreach could bridge the gap between academia and the general public, facilitating broader societal impact.

Education:

Dr. Huining He earned her Ph.D. in Chemical Engineering from Tianjin University, where she gained profound expertise in biomaterials and drug delivery systems. During her doctoral studies, she participated in joint training at the University of Michigan, an experience that greatly expanded her research skills and international perspective. This training allowed her to engage in cutting-edge projects in the fields of biomaterials and drug delivery. Her advanced education laid the foundation for her future contributions to biomedical engineering, especially in the development of novel targeted systems for gene therapy and cancer treatment. Dr. He’s academic journey has been marked by strong mentorship, international collaborations, and her leadership role in several research projects that have significantly advanced the biomedical field.

Experience:

Dr. Huining He’s career in biomedical engineering spans extensive academic and research experience. Currently, as the Dean of the School of Biomedical Engineering and Technology at Tianjin Medical University, she leads a dynamic department focused on advancing healthcare solutions through innovative research. She has supervised numerous Ph.D. students, guiding them in pioneering research on biomaterials and drug delivery systems. Her work has been recognized by the Ministry of Education, with prestigious titles such as the “Young Changjiang Scholar.” Dr. He has led and contributed to several high-profile research projects funded by China’s National Natural Science Foundation, including investigations into enzyme-sensitive targeted systems for gene therapy and glioma treatment. Beyond academia, she has participated in industry projects, translating her research into real-world applications. As a member of numerous professional organizations and editorial boards, Dr. He plays a vital role in facilitating international collaborations and advancing scientific knowledge in the biomedical sector.

Research Focus:

Dr. Huining He’s research focuses on the design and development of advanced biomaterials and drug delivery systems, particularly in the treatment of cancer and other serious diseases. Her work involves creating innovative, targeted drug delivery systems that can enhance the efficacy and precision of treatment. She has conducted pivotal studies on enzyme-sensitive targeted systems for gene therapy, improving the delivery of therapeutic agents to cancer cells. Currently, Dr. He is leading several projects on siRNA co-delivery systems for glioma, investigating ways to overcome the challenges in glioma treatment. Her research also covers the development of prodrug-type macromolecular systems and multifunctional exosome-based drug delivery technologies. Dr. He’s work has the potential to revolutionize cancer treatment and other therapeutic approaches, contributing to the development of more efficient, less toxic therapies for patients. Her research continues to make substantial advancements in the fields of drug delivery, biomedical engineering, and cancer therapy.

Publications Top Notes:

  1. CaCO3-based nanomedicine with multi-functions of ferroptosis-apoptosis and microenvironment regulation in cancer 🔬💡 (Nano Today, 2025)
  2. Lipid Nanoparticular Codelivery System for Enhanced Antitumor Effects by Ferroptosis-Apoptosis Synergistic with Programmed Cell Death-Ligand 1 Downregulation 🧬⚡ (ACS Nano, 2024)
  3. Nanomedicine integrating the lipidic derivative of 5-fluorouracil, miriplatin and PD-L1 siRNA for enhancing tumor therapy 💊🧪 (Chinese Chemical Letters, 2024)
  4. A review on gold nanoparticles as an innovative therapeutic cue in bone tissue engineering: Prospects and future clinical applications 🏥🔬 (Materials Today Bio, 2024)
  5. Lipid core-shell nanoparticles co-deliver FOLFOX regimen and siPD-L1 for synergistic targeted cancer treatment 🧬🔗 (Journal of Controlled Release, 2024)
  6. An injectable signal-amplifying device elicits a specific immune response against malignant glioblastoma 💉🧠 (Acta Pharmaceutica Sinica B, 2023)
  7. Antitumor synergism between PAK4 silencing and immunogenic phototherapy of engineered extracellular vesicles 🧬💥 (Acta Pharmaceutica Sinica B, 2023)
  8. Dual-sensitive drug-loaded hydrogel system for local inhibition of post-surgical glioma recurrence 💧⚔ (Journal of Controlled Release, 2022)
  9. Antibody–siRNA conjugates (ARC): Emerging siRNA drug formulation 🧬💉 (Medicine in Drug Discovery, 2022)
  10. mRNA vaccines for COVID-19 and diverse diseases 💉🦠 (Journal of Controlled Release, 2022)

Conclusion:

Dr. Huining He’s exceptional contributions to the field of biomedical engineering, particularly in the development of novel drug delivery systems for cancer treatment, position her as an ideal candidate for the Best Researcher Award. Her innovative work, combined with a clear vision for the future of precision medicine, continues to drive the field forward. She has the potential to further revolutionize medical treatments, making her a deserving nominee for this prestigious recognition.