Jacob Wekalao | Cancer Cell Biology | Best Researcher Award

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Mr. Jacob Wekalao | Cancer Cell Biology | Best Researcher Award

Mr. Jacob Wekalao , USTC CHINA , China

Jacob Wekalao is a Physics professional and researcher with extensive experience in both academia and industry. He holds a Doctor of Philosophy from the University of Science and Technology and a Master of Science in Physics from Marwadi University, India. Jacob has worked as a physics teacher, leading the physics department at Kwale High School, Kenya, and is currently a software expert at Eujim Solutions, where he specializes in creating innovative business solutions. He is also a Research Assistant at Marwadi University, contributing to advanced research in physics and nanotechnology. His expertise spans across terahertz sensors, graphene-based biosensors, and surface plasmon resonance techniques. In addition to his academic endeavors, Jacob has authored several peer-reviewed publications, showcasing his contributions to forensic science, health, and biomedical applications. Jacob is passionate about research, mentoring, and leveraging technology to solve real-world problems.

Publication Profile:

Orcid

Strengths for the Award:

Jacob Wekalao is an exceptional researcher in the field of experimental physics, particularly in the areas of nanotechnology, terahertz sensors, and biosensing. His work integrates cutting-edge research with practical applications, demonstrating a high level of innovation and expertise. Jacob’s contributions to the development of graphene-based sensors for various applications, including healthcare, forensic science, and security, have positioned him as a thought leader in his field. His published works in prestigious journals and his active role in research projects, such as designing biosensors for early disease detection, highlight his proficiency in both theoretical and applied physics. Additionally, Jacob’s ability to collaborate internationally and present at major conferences reflects his commitment to advancing scientific knowledge and networking within the global research community.

Areas for Improvement:

While Jacob excels in his research and technological expertise, expanding his focus on interdisciplinary collaborations could further elevate his work. Engaging more with industry experts in areas like artificial intelligence or machine learning could also open doors for more transformative innovations, especially in optimizing sensor technologies. Further involvement in policy or public science initiatives could help bridge the gap between research and broader societal applications.

Education:

Jacob Wekalao has an impressive educational background that supports his expertise in physics and technology. He is currently pursuing a Doctor of Philosophy at the University of Science and Technology, China. His academic journey began with a Bachelor of Education in Science with a focus on Physics and Mathematics from the University of Embu, Kenya (2016-2020). This solid foundation propelled him to obtain a Master of Science in Physics from Marwadi University, Rajkot, Gujarat, India (2021-2023). During his time at Marwadi University, Jacob excelled academically, earning an Academic Gold Medal in November 2023 for his outstanding performance. His commitment to learning is also reflected in certifications from institutions like KAIST and the Israel Institute of Technology. Jacob’s education is characterized by a blend of theoretical knowledge and practical skills, which has enabled him to contribute significantly to the fields of experimental physics and applied technology.

Experience:

Jacob Wekalao has diverse experience spanning education, research, and industry. From September 2019 to August 2021, he worked as a Physics teacher at Kwale High School, Kenya, where he led the physics department, developed curriculum materials, and managed science projects. This role enabled him to foster critical thinking and scientific inquiry among students. In addition to his teaching experience, Jacob is currently employed as a Software Expert at Eujim Solutions, Kenya (July 2023 – Present), where he provides tailored software solutions, improves business efficiency, and implements cutting-edge technologies. Furthermore, he works as a Research Assistant at Marwadi University, collaborating on various physics research projects focused on terahertz sensors and biosensors. His involvement in multiple projects and publications has established him as a valuable contributor to advancements in technology and scientific research. Jacob’s work showcases a seamless integration of theoretical physics and practical application in technology.

Awards and Honors:

Jacob Wekalao’s dedication to academic excellence and research has earned him notable awards and honors. He received the prestigious Academic Gold Medal from Marwadi University, Rajkot, India, in November 2023, recognizing his exceptional performance in the Master of Science in Physics program. Jacob’s achievements are further validated by his numerous peer-reviewed publications, which have contributed to the global scientific community. His research in the fields of biosensing, terahertz technology, and nanomaterials has earned him recognition at various international platforms. In addition to academic awards, Jacob’s work has been presented at leading conferences, such as the International Conference on Chemical Safety and Security for Health and Environment (ICCSSHE), held in India in December 2023. His strong academic performance, leadership in research, and contributions to technological advancements continue to set him apart as an outstanding professional in his field.

Research Focus:

Jacob Wekalao’s research focuses on experimental physics, particularly in the areas of terahertz technology, biosensing, and nanomaterials. His work has significant implications for applications in healthcare, security, and forensic science. Jacob has developed and optimized graphene-based terahertz surface plasmon resonance sensors for the detection of various biomolecules, including hemoglobin and illicit drugs. His research has extended to the design of graphene metasurfaces for efficient detection of diseases like malaria and COVID-19. Jacob’s research in biosensors has led to highly sensitive, cost-effective solutions that hold promise for point-of-care diagnostics and environmental monitoring. Additionally, his work on the use of metasurfaces for explosive detection has practical implications for security. Through his research, Jacob combines advanced theoretical physics with real-world applications, contributing to the fields of biomedical technology, environmental monitoring, and security. His interest in machine learning also aids in optimizing these sensor technologies for better precision and performance.

Publications Top Notes:

  1. “Graphene-based THz surface plasmon resonance biosensor for hemoglobin detection applicable in forensic science.” 📖🔬
  2. “Design of ring and cross-shaped graphene metasurface sensor for efficient detection of malaria and 2-bit encoding applications.” 🦠🔍
  3. “Waterborne bacteria detecting highly sensitive graphene metasurface-based cost-efficient and efficient refractive index sensors.” 💧🔬
  4. “Design of graphene metasurface sensor for efficient detection of COVID-19.” 🦠💡
  5. “Graphene biosensor design based on glass substrate for forensic detection of illicit drugs.” 💊🔍
  6. “Graphene and Gold Metasurface-Based Terahertz Surface Plasmon Resonance Sensor for Explosive Detection.” 💥🛡️
  7. “Terahertz Optical Ultrasensitive Glucose Detection Using Graphene and Silver Surface Plasmon Resonance Metasurfaces for Biomedical Applications.” 🩺🔬
  8. “High-Sensitivity Graphene-Gold Metasurface Optical Biosensor for Early Melanoma Detection Optimized with Machine Learning Using a One-Dimensional Convolutional Neural Network and Binary Encoding.” 🧬🔬

Conclusion:

Jacob Wekalao’s contributions to the fields of physics and technology demonstrate an impressive combination of academic excellence, hands-on expertise, and innovative solutions. His drive to advance scientific knowledge and apply it for real-world impact, especially in healthcare and security, makes him a deserving candidate for the Best Researcher Award. Jacob’s ongoing work on high-sensitivity biosensors and his ability to stay ahead of technological trends make him a standout researcher in his field.

 

 

 

Rika Sasaki | mitochondria | Best Researcher Award

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Dr. Rika Sasaki | mitochondria | Best Researcher Award

Dr. Rika Sasaki , Department of Molecular Pathology, Nara Medical University , Japan

Rika Sasaki is a researcher in the Department of Molecular Pathology at Nara Medical University, Japan. She completed her degree in Medicine from the Faculty of Medicine, Nara Medical University in March 2023 and began her doctoral studies in April 2023. Currently, she is in the second year of her program, focusing on cancer research, particularly on the role of mitochondrial transfer in colorectal cancer. Rika is passionate about understanding the molecular mechanisms behind cancer malignancy and drug resistance. She has a growing academic presence, having published multiple papers in respected journals such as the International Journal of Molecular Sciences. Her work has contributed to important discoveries, including the identification of HMGB1 as a key factor in mitochondrial transfer. Rika is a member of The Japanese Cancer Association and The Japanese Society of Pathology, and she is dedicated to furthering cancer-related research.

Publication Profile:

Scopus

Strengths for the Award:

Rika Sasaki has demonstrated considerable promise as a young researcher in the field of molecular pathology, with a focused interest in cancer biology. Sasaki’s research on the therapeutic strategy for targeting drug resistance in colorectal cancer through mitochondrial transfer is both innovative and highly relevant. Her ability to identify key molecules, such as oxidized HMGB1, contributing to cancer malignancy and resistance, highlights her potential to shape future cancer therapies. Moreover, Sasaki’s publication record, including in high-impact journals, showcases the quality and impact of her work. Her membership in esteemed professional societies further strengthens her standing in the research community.

Areas for Improvement:

Although Sasaki is an emerging researcher with promising contributions, expanding her network through collaborative research and increasing the breadth of her publications could enhance her visibility in the scientific community. Additionally, the exploration of translational research, particularly through clinical applications, could be an important avenue for the future development of her work.

Education:

Rika Sasaki earned her degree in Medicine from the Faculty of Medicine at Nara Medical University in March 2023. Shortly after graduation, she enrolled in the Doctoral Program at Nara Medical University in April 2023. As of February 2025, she is in the second year of her Ph.D. studies. During her academic career, Rika has demonstrated a strong commitment to medical and scientific research. Her education has provided her with a solid foundation in molecular pathology, particularly with an emphasis on cancer biology. Rika’s research interests have led her to focus on understanding the intricate mechanisms of drug resistance in cancer cells, particularly in colorectal cancer. Her research findings are contributing to the development of potential therapeutic strategies, which may play a significant role in overcoming treatment resistance. Her academic journey reflects dedication, rigor, and a passion for advancing medical knowledge.

Experience:

Rika Sasaki’s professional journey as a researcher began after her graduation from Nara Medical University in March 2023, when she immediately began her Doctoral Program. As a second-year Ph.D. student, she has already been involved in groundbreaking research focused on cancer drug resistance mechanisms. Her experience includes working on the project titled “Therapeutic Strategy for Colorectal Cancer Targeting Drug Resistance Induced by Mitochondrial Transfer.” Rika’s research highlights the oxidized form of HMGB1 as a major factor in mitochondrial transfer, contributing to cancer cell stemness and drug resistance. She has also collaborated with a team of scientists, publishing several research articles in peer-reviewed journals. Though she does not have formal consultancy or industry experience yet, Rika’s academic achievements and publication record indicate her growing expertise in molecular pathology. She is currently refining her skills and knowledge, positioning herself as a future leader in cancer research.

Awards and Honors:

Rika Sasaki, while early in her career, has made significant strides in cancer research, particularly focusing on mitochondrial transfer and drug resistance in colorectal cancer. She has not yet received formal awards for her work; however, her research has been published in respected journals such as the International Journal of Molecular Sciences, underlining her scientific contributions. Rika’s H-index of 5 reflects the growing impact of her publications. Although she has not received awards such as the Best Researcher Award yet, her innovative work has attracted recognition within her institution and the scientific community. As her research progresses, particularly in understanding cancer drug resistance, Rika is likely to gain more recognition in the coming years. Her academic commitment and contributions to molecular pathology have earned her membership in notable professional societies like The Japanese Cancer Association and The Japanese Society of Pathology, setting her up for future accolades.

Research Focus:

Rika Sasaki’s research primarily revolves around understanding cancer drug resistance, particularly in colorectal cancer. Her focus is on the therapeutic strategy targeting mitochondrial transfer that promotes cancer cell stemness and resistance to conventional chemotherapy. Through her research, she has identified the oxidized form of HMGB1 as a key factor that accelerates mitochondrial transfer from mesenchymal stem cells to colorectal cancer cells. This discovery holds potential for novel cancer therapies aimed at reversing drug resistance. Rika’s research also extends to studying energy metabolism and the role of various molecules, such as lauric acid, in overcoming chemoresistance. Her work provides critical insights into the molecular mechanisms underlying the malignancy of cancer cells, contributing to the development of more effective treatments. Rika’s research bridges molecular pathology and clinical applications, making her a promising scientist in the fight against cancer. Her findings are already influencing the field of cancer research, making her work highly relevant.

Publications Top Notes:

  • Oxidative stress
  • “Oxidative High Mobility Group Box-1 Accelerates Mitochondrial Transfer from Mesenchymal Stem Cells to Colorectal Cancer Cells Providing Cancer Cell Stemness” (Int. J. Mol. Sci. 2025) 📚💥
  • “Energy Metabolism and Stemness and the Role of Lauric Acid in Reversing 5-Fluorouracil Resistance in Colorectal Cancer Cells” (Int. J. Mol. Sci. 2025) 🍏🔬
  • “Significance of CD10 for Mucosal Immunomodulation by β-Casomorphin-7 in Exacerbation of Ulcerative Colitis” (Curr. Issues Mol. Biol. 2024) 🔬🧬
  • “Effects of High-Mobility Group Box-1 on Mucosal Immunity and Epithelial Differentiation in Colitic Carcinoma” (Int. J. Mol. Sci. 2024) 🔬🦠
  • “Berberine Improves Cancer-Derived Myocardial Impairment in Experimental Cachexia Models by Targeting High-Mobility Group Box-1” (Int. J. Mol. Sci. 2024) 💪🧪
  • “Nuclear MAST4 Suppresses FOXO3 through Interaction with AKT3 and Induces Chemoresistance in Pancreatic Ductal Carcinoma” (Int. J. Mol. Sci. 2024) 💥🧠
  • “Investigation of Cancer-Induced Myocardial Damage in Autopsy Cases—A Comparison of Cases with and without Chemotherapy” (Pathol. Int. 2024) 🧠❤️
  • “Pterostilbene Induces Apoptosis from Endoplasmic Reticulum Stress Synergistically with Anticancer Drugs That Deposit Iron in Mitochondria” (Int. J. Mol. Sci. 2024) 🧪💔
  • “Involvement of Ferroptosis Induction and Oxidative Phosphorylation Inhibition in the Anticancer-Drug-Induced Myocardial Injury: Ameliorative Role of Pterostilbene” (Int. J. Mol. Sci. 2024) ⚡🧬
  • “Lauric Acid Overcomes Hypoxia-Induced Gemcitabine Chemoresistance in Pancreatic Ductal Adenocarcinoma” (Int. J. Mol. Sci. 2023) 🧪🍃

Conclusion:

Given her strong academic background, innovative research on cancer biology, and growing publication record, Rika Sasaki is a strong candidate for the Best Researcher Award. Her work on mitochondrial transfer and cancer resistance mechanisms promises significant advancements in cancer treatment. With continued professional growth and wider collaborations, she has the potential to make substantial contributions to medical science.

 

 

Vaibhav Rajoriya | Cancer Cell Biology | Cell Biology Research Award

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Mr. Vaibhav Rajoriya | Cancer Cell Biology | Cell Biology Research Award

Mr. Vaibhav Rajoriya , Oriental University, Indore , India

Vaibhav Rajoriya is a dedicated and accomplished researcher and pharmacist based in Sagar, Madhya Pradesh, India. With a strong academic background, he has earned his B.Pharm and M.Pharm from renowned institutions. He is a registered pharmacist with the MP State Pharmacy Council and holds memberships in various professional organizations, including the Association of Pharmacy Professionals. As a passionate researcher, Vaibhav has contributed to numerous studies, particularly focusing on nanomedicine, drug delivery systems, and cancer therapies. He has received prestigious fellowships such as ICMR-SRF and CSIR-SRF, contributing significantly to the field of pharmaceutical sciences. Currently pursuing a Ph.D., Vaibhav’s work continues to push boundaries in pharmaceutical research and development. His drive for excellence is further reflected in his active participation in various national and international conferences and research collaborations.

Publication Profile:

Orcid

Strengths for the Award:

  1. Diverse and Strong Research Background:
    • Vaibhav Rajoriya has a robust academic and research profile, with an established history of contributions to pharmaceutical sciences, particularly in the areas of drug delivery, nanotechnology, and cancer therapies.
    • He has authored multiple publications in high-impact journals, such as International Journal of Pharmaceutics and Current Nanomedicine, which demonstrate his expertise in nanomedicine, drug delivery systems, and the pharmaceutical applications of lipid nanoparticles and nanogels.
    • His focus on cutting-edge research areas, such as lung cancer targeting with folate-conjugated nanoparticles and novel drug delivery systems using solid lipid nanoparticles, shows a clear alignment with important biological research themes, including targeted therapy and cellular uptake.
  2. Research Achievements and Awards:
    • He has received prestigious recognitions, such as the MPCST Young Scientist Award and Best Poster Awards from institutions like AIIMS, Rishikesh, and IIT-BHU. These accolades reflect the high quality and relevance of his work in the biomedical field.
    • His successful completion of ICMR-SRF and CSIR-SRF fellowships exemplifies his ability to lead significant research projects. Moreover, he has actively contributed to a variety of projects in pharmaceutical science, indicating a deep understanding of the complexities of drug formulations, targeting mechanisms, and therapeutic applications.
  3. Ph.D. Candidacy and Future Potential:
    • Vaibhav Rajoriya is currently pursuing a Ph.D. at Oriental University, Indore, demonstrating his commitment to further advancing his research capabilities and contributing to cutting-edge research in cell biology and drug development.
    • His experience and involvement in multi-disciplinary projects, along with his fellowship positions, position him to be a strong contender for advanced research awards, including in the field of cell biology.
  4. Collaborative and Multi-dimensional Approach:
    • His involvement in collaborative research is evident through co-authorship in studies that blend different scientific approaches (nanotechnology, pharmacology, and medicinal chemistry). Such collaborations show his adaptability and the potential for cross-pollination of ideas between different scientific domains, an important characteristic in cell biology research.

Areas for Improvement:

  1. Focus on Cell Biology-Specific Research:
    • While Vaibhav’s work in nanomedicine and drug delivery systems has implications for cell biology, the research could benefit from a more explicit focus on cell biology topics such as cell signaling, cell-matrix interactions, or cell morphology, particularly at the molecular level.
    • His research could further explore in vivo and ex vivo models to study the cellular response in the context of drug delivery, providing a direct link to cellular behavior and biological mechanisms.
  2. Publication Expansion in Cell Biology Journals:
    • While his work is widely published in pharmaceutically inclined journals, increasing the number of publications directly in cell biology and molecular biology journals would provide a stronger case for this specific award. It could enhance his visibility and establish his position as a leading researcher in this field.
  3. Broader Approach to Targeted Drug Delivery in Cell Biology:
    • The research could be expanded by investigating multi-targeted delivery systems that engage specific cell types or signaling pathways, thereby providing deeper insights into cellular responses to treatment, as well as optimizing efficacy in various disease models, particularly cancer and genetic disorders.

Education:

Vaibhav Rajoriya’s educational journey is marked by a focus on pharmaceutical sciences and research. He completed his Standard X and XII from Jain Higher Secondary School, Sagar, achieving 69% and 68%, respectively. Vaibhav pursued his B.Pharm from Sagar Institute of Pharmaceutical Sciences, securing 70.4% and completed his M.Pharm at Adina Institute of Pharmaceutical Sciences with an impressive 79.9%. In addition to his pharmaceutical qualifications, Vaibhav obtained a PGDCA (Post Graduate Diploma in Computer Applications) from Agrabhan Institute of Excellence. His pursuit of knowledge led him to enroll in a Ph.D. program at Oriental University, Indore, in 2022, to further his expertise in pharmaceutical research. Throughout his academic career, he has demonstrated a strong foundation in various fields, including drug delivery systems and nanotechnology, which continues to shape his innovative research.

Experience”

Vaibhav Rajoriya has extensive experience in the field of pharmaceutical sciences, with a career that spans various research positions and projects. He was a Junior Research Fellow (JRF) in the DST-SERB-sponsored project from May 2016 to June 2018, followed by a Project Fellow position in the MPCST-sponsored research project from 2014 to 2016. These roles allowed him to gain hands-on experience in scientific research, contributing to the advancement of drug delivery systems and nanomedicine. Vaibhav has been awarded prestigious fellowships, including the ICMR-SRF (2018–2021), which further honed his skills in biomedical research. He has worked on numerous research topics, particularly focused on targeted drug delivery for cancer and other diseases, which resulted in multiple publications in high-impact journals. Vaibhav’s expertise spans the development of nanoparticle-based drug delivery systems, nano-lipid carriers, and the formulation of pharmaceutical compounds with specific targeting properties.

Awards and Honors:

Vaibhav Rajoriya’s exceptional contributions to pharmaceutical sciences have earned him several prestigious awards and honors. Notably, he was the recipient of the MPCST Young Scientist Award in 2018, recognizing his contributions to innovative research in nanomedicine. He has also earned accolades for his research presentations, including the Best Poster Award at AIIMS, Rishikesh, in 2018, for his work on folate-conjugated solid lipid nanoparticles for cancer treatment. In addition, Vaibhav won the Outstanding Poster Presentation Award in the Life Sciences category at the 1st National Biomedical Research Competition in 2018. His work at the 3rd SPIRIT 2019 conference earned him the 3rd position in the poster presentation, further highlighting his research prowess. These accolades reflect Vaibhav’s deep commitment to advancing pharmaceutical research, particularly in targeted drug delivery systems and cancer therapies, as well as his ability to effectively communicate his findings on national and international platforms.

Research Focus:

Vaibhav Rajoriya’s research focus lies primarily in the development of novel drug delivery systems, particularly for cancer treatment and other chronic diseases. His work explores the use of nanomedicine, including the formulation of solid lipid nanoparticles, nano-lipid carriers, and targeted drug delivery systems. Vaibhav’s research aims to enhance the bioavailability and therapeutic efficacy of drugs, particularly in targeted therapies for lung carcinoma and other cancers. He is particularly interested in the design and optimization of nanoparticles conjugated with targeting moieties such as folate and mannosylation to improve cellular uptake and reduce side effects. Through his research, Vaibhav has contributed to the advancement of nanocarriers for targeted drug delivery, studying their physicochemical properties, drug release profiles, cytotoxicity, and in vivo behavior. His focus is on using cutting-edge nanotechnology to create more effective and precise drug therapies for patients, particularly in oncology and infectious diseases.

Publications Top Notes:

  1. “Lactosaminated-Nsuccinyl Chitosan Nanoparticle for Hepatocyte-Targeted Delivery of Acyclovir” 🧬
  2. “Glycyrrhizin Conjugated Chitosan Nanoparticles for Hepatocyte-Targeted Delivery of Lamivudine” 💊
  3. “Mannosylated Solid Lipid Nanoparticles for Lung Targeted Delivery of Paclitaxel” 🌱
  4. “Folate-Conjugated Albumin Nanoparticles for Rheumatoid Arthritis-Targeted Delivery of Etoricoxib” 🦴
  5. “Development and Validation of RP-HPLC Method for Theophylline and Motelukast Estimation” 🔬
  6. “Evaluation of Ethanolic Extract of Zizyphus Xylopyrus on Wound Healing Activity” 🩹
  7. “Formulation Development and Evaluation of Fast Dissolving Tablet of Ramipril” 💊
  8. “UV-Spectrophotometric and Stability-Indicating RP-HPLC Method for Amlodipine and Indapamide” 📊
  9. “Folate-Conjugated Nano-Lipid Construct of Paclitaxel for Site-Specific Lung Squamous Carcinoma Targeting” 🫁
  10. “Nanostructured Lipid Carriers for Lung Cancer Targeting” 💥

Conclusion:

Vaibhav Rajoriya is a highly capable and promising researcher with strong achievements in pharmaceutical sciences, nanomedicine, and drug delivery systems. His research in the area of targeted drug delivery to specific cell types (e.g., cancer cells) already touches on key aspects of cell biology. His extensive background in various fellowships and awards underscores his dedication and success in research.