Prof. Arzu Yay is a distinguished researcher in the Department of Histology and Embryology at Erciyes University, Turkey. Her work focuses on cellular and molecular mechanisms underlying tissue development, injury, and repair, with emphasis on immunohistochemical and ultrastructural analyses. Her M.Sc. research examined E-cadherin expression during renal development in the prenatal period, contributing to the understanding of epithelial differentiation in organogenesis. Her Ph.D. focused on nestin expression across different grades of meningiomas and glioblastomas, highlighting neural stem cell marker dynamics in tumor progression. She has conducted significant studies on oxidative stress, neurobiology, and tissue damage, including investigations into the effects of melatonin and vitamin C on alcohol-induced lung injury and nitric oxide synthase immunoreactivity. Her research has also explored tissue-level alterations in diabetes and the histological impacts of hormonal and anesthetic agents. Prof. Yay’s postdoctoral work at the University of Lübeck, Germany, further advanced her expertise in dermatological histopathology. Her contributions have been recognized through multiple national and international awards for excellence in experimental and translational research, particularly in antioxidant mechanisms and radioprotection. Her body of work reflects a strong integration of histological, molecular, and ultrastructural approaches in biomedical sciences.
Featured Publications:
Yıldız, K., Efesoy, S. N., Ozdamar, S., Yay, A., Bicer, C., Aksu, R., & Kılıc, E. (2011). Myotoxic effects of levobupivacaine, bupivacaine and ropivacaine in a rat model. Clinical Investigation in Medicine, 34(5), 273–280.
Sarıozkan, S., Bucak, M. N., Canturk, F., Ozdamar, S., Yay, A., Tuncer, P. B., Ozcan, S., Sorgucu, N., & Caner, Y. (2012). The effects of different sugars on motility, morphology and DNA damage during the liquid storage of rat epididymal sperm at 4°C. Cryobiology, 65(2), 93–97.
Sarıozkan, S., Canturk, F., Yay, A., & Akçay, A. (2012). The effect of different storage temperature on sperm parameters and DNA damage in liquid stored New Zealand rabbit spermatozoa. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 18(3), 475–480.*
Yay, A., Ozdamar, S., Canoz, O., Tucer, B., & Baran, M. (2013). Nestin expression in meningiomas of different grades. Journal of Neurological Sciences (Turkish), 30, 532–540.
Sarıozkan, S., Türk, G., Canturk, F., Yay, A., Eken, A., & Akçay, A. (2013). The effect of bovine serum albumin and fetal calf serum on sperm quality, DNA fragmentation and lipid peroxidation of liquid stored rabbit semen. Cryobiology, 67(1), 1–6.*
Ernst, N., Yay, A., Bíró, T., Tiede, S., Humphries, M., Paus, R., & Kloepper, J. E. (2013). β1 integrin signaling maintains human epithelial progenitor cell survival in situ and controls proliferation, apoptosis and migration of their progeny. PLoS ONE, 8(12), e84356.*
Yay, A., Ozdamar, S., Canoz, O., Baran, M., Tucer, B., & Sonmez, M. F. (2014). Intermediate filament protein nestin is expressed in developing meninges. Bratislava Medical Journal, 115(11), 718–722.*