Yanqi Dang | Cancer Cell Biology | Editorial Board Member

Mr. Yanqi Dang | Cancer Cell Biology | Editorial Board Member

Institute of Digestive Diseases, Longhua Hospital, China-Canada Center of Research for Digestive Diseases, Shanghai University of Traditional Chinese Medicine, Shanghai 200032 | China

The researcher focuses on the epigenetic regulation of metabolic diseases and tumorigenesis, with major contributions in colorectal cancer (CRC) diagnostics, mechanisms, and traditional Chinese medicine (TCM)-based interventions. In early CRC detection, the team performed transfer RNA (tRNA) sequencing and identified two key tRFs—tRF-Tyr-GTA-081 (downregulated) and tRF-Ala-AGC-060 (upregulated)—whose combined diagnostic model demonstrated strong performance for colorectal neoplastic lesions and cancer, outperforming traditional markers such as CEA and CA199. Multi-omics analyses of mRNAs, miRNAs and circRNAs identified three circRNAs with predictive value for adenoma–carcinoma transition. Through DNA hydroxymethylation sequencing, ZW10 emerged as a prognostic-related marker, and its circulating hydroxymethylation level showed high accuracy for early CRC detection. Mechanistic studies revealed that METTL3 regulates CRB3 in an m6A-dependent manner to modulate HIPPO signaling, while DNMT3B- and TET2-mediated epigenetic modifications jointly control PGC-1α to promote CRC progression. In therapeutic research, Scutellaria baicalensis Tang, Sijunzi Tang, and related monomers are under investigation for anti-CRC effects. In metabolic disease research, Ling-Gui-Zhu-Gan decoction and cinnamaldehyde were shown to improve steatosis and insulin resistance in NAFLD, supporting the TCM concept of “phlegm-beverage.” Current studies focus on lean NAFLD, demonstrating that METTL14 regulates TIM3 to influence disease development, and that GJLZ decoction alleviates steatosis and inflammation by enhancing this pathway.

Profile: Scopus

Featured Publications:

Ma, J., …, & al. (2025). Regulation of histone H3K27 methylation in inflammation and cancer.

Shaoqing Ai | Cancer | Best Researcher Award

Mr. Shaoqing Ai | Cancer | Best Researcher Award

Xi’an Daxing Hospital | China

Dr. Shaoqing Ai’s research focuses on the clinical application and translational potential of integrated traditional Chinese and Western medicine in oncology, particularly in the management of gastrointestinal tumors, lung cancer, and gynecological malignancies. His work emphasizes optimizing multidisciplinary treatment strategies and improving patient outcomes through precision diagnosis and therapy. As an active contributor to the fields of tumor metastasis and geriatric oncology, he has participated in a research project exploring the molecular mechanisms and clinical management of tumor progression and treatment-related complications. His published studies, including one SCI-indexed paper and two Chinese core journal articles, highlight the therapeutic efficacy of combined treatment approaches in reducing radiotherapy- and chemotherapy-induced hematologic toxicities such as leukopenia and thrombocytopenia. Dr. Ai’s research also aims to refine clinical protocols for mitigating adverse effects while enhancing the overall quality of life for cancer patients. Through his involvement in professional oncology committees and collaborative studies, he continues to advance the integration of evidence-based Chinese medicine with modern oncological practices, contributing to the growing body of knowledge supporting individualized and holistic cancer care.

Profile: Orcid

Featured Publications:

Ai, S., Jun, G., Jia, W., & Jie, L. (2025, October 16). Correlation analysis between frequency of gastrointestinal bleeding episodes and abnormal coagulation indexes in digestive system tumors. Scientific Reports. https://doi.org/10.1038/s41598-025-19012-8

 

 

Yavuz Tekelioğlu | Cancer Cell Biology | Best Academic Researcher Award

Prof. Dr. Yavuz Tekelioğlu | Cancer Cell Biology | Best Academic Researcher Award

Prof. Dr. Yavuz Tekelioğlu | Karadeniz Technical University | Turkey

Prof. Dr. Yavuz Tekelioğlu is a distinguished professor at Karadeniz Technical University’s Faculty of Medicine, specializing in histology, embryology, and toxicology. He has built a prolific academic career focused on cellular and tissue analysis using advanced methods like flow cytometry. Since beginning as a research assistant, he has steadily advanced through academic ranks, culminating in a full professorship. He has supervised numerous theses, contributing significantly to training future scientists. His research emphasizes the protective effects of antioxidants and stem cell therapies on tissue toxicity, with over 100 peer-reviewed publications. Active in professional societies, he also provides comprehensive educational instruction in medicine and dentistry. Prof. Tekelioğlu is committed to advancing biomedical research, particularly in reproductive and hepatic toxicology, through innovative experimental approaches.

Publication Profile:

Scopus

Education:

Prof. Dr. Yavuz Tekelioğlu completed his higher education at Karadeniz Technical University, where he earned his PhD after serving as a research assistant. His academic foundation is firmly rooted in medical sciences, with a focus on histology and embryology. During his doctoral studies, he developed expertise in experimental toxicology and cellular biology, particularly utilizing flow cytometry for immunophenotyping. His training includes specialized certifications in scientific research ethics, flow cytometry techniques, and institutional educational management. These credentials equip him to conduct rigorous, ethical research and provide effective academic leadership. Continuous participation in national and international workshops and symposiums reflects his commitment to staying current with cutting-edge methodologies and ethical standards in biomedical research.

Experience:

Starting as a research assistant, Prof. Tekelioğlu quickly advanced to PhD research assistant, assistant professor, associate professor, and finally full professor at Karadeniz Technical University. Over more than three decades, he has taught histology and embryology to medical, dental, and graduate students while supervising numerous theses on tissue toxicity and protective agents. He has led multiple TÜBİTAK and university-funded projects focusing on mesenchymal stem cells and toxicological evaluations using flow cytometry and histopathology. His academic service extends to practical flow cytometry training, contributing to capacity building in biomedical research. His administrative roles include coordinating research ethics training and educational management. He is a member of prominent scientific societies, contributing to Turkey’s scientific community. His career demonstrates dedication to both research and education.

Research Focus:

Prof. Dr. Tekelioğlu’s research primarily focuses on the histopathological and immunological effects of toxic agents on reproductive and hepatic tissues. His work extensively explores the protective roles of antioxidants like vitamin E, lycopene, beta-glucan, and Coenzyme Q10 against methotrexate-induced toxicity. Employing flow cytometry, histology, and biochemical assays, his studies provide mechanistic insights into cellular apoptosis, oxidative stress, and tissue regeneration. He investigates mesenchymal stem cells for their therapeutic potential in tissue repair and immunomodulation. His experimental models often include rats and mice, enabling controlled studies of drug-induced organ damage and protective interventions. By bridging toxicology with cellular analysis, his research contributes to safer clinical drug use and novel treatment strategies. Additionally, his recent work on ovarian and cardiac protection highlights translational relevance. His interdisciplinary approach combines toxicology, reproductive biology, and flow cytometry, establishing him as a leader in biomedical research.

Publication Top Notes: 

  • Coenzyme Q10 may protect ovarian tissue against methotrexate-induced gonadotoxicity: a biochemical, flow cytometric, and histopathological study

  • A Comparison of the Flow Cytometric Analysis Results of Benign and Malignant Serous Tumors of the Ovary

  • Should combined MTX and CoQ10 use be reconsidered in terms of steatosis? A biochemical, flow cytometry, histopathological experimental study

  • Histological and flow cytometric evaluation of astaxanthin’s effects against cyclophosphamide induced heart injury in rats

  •  Melamine exposure during the weaning period negatively affects ovarian reserve

Conclusion:

Prof. Dr. Yavuz Tekelioğlu is well-qualified and highly suitable for the Best Academic Researcher Award based on his extensive career, strong research leadership, significant scholarly contributions, and educational impact. His focused expertise on toxicology, histology, and cellular analysis is both relevant and impactful.

With strategic enhancements in international collaborations and visibility, he can further solidify his standing as a leading academic researcher. Nonetheless, his current achievements and dedication clearly merit recognition at this level.