Dominique Heymann | Cancer Cell Biology | Best Researcher Award

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Prof. Dr. Dominique Heymann | Cancer Cell Biology | Best Researcher Award

Prof. Dr. Dominique Heymann , Nantes Université, CNRS, Institut de Cancérologie de l”Ouest , France

Professor Dominique Heymann is a highly esteemed academic and clinician, specializing in histology, embryology, and oncology. He is a Professor at Nantes University, France, and a Hospital Practitioner at the ICO Cancer Centre. With a wealth of experience in bone oncology and cancer research, he is also an Honorary Professor at the University of Sheffield, UK. His expertise spans from cell biology to immunology and biochemistry, and he is dedicated to advancing cancer research, particularly in the field of bone tumors and osteosarcoma. With numerous publications to his name and contributions to the global scientific community, Professor Heymann is recognized for his groundbreaking work in cell signaling and tumor progression. He is a valued researcher in the oncology community, with a strong focus on developing innovative therapies for cancer treatment.

Publication Profile:

Google Scholar

Strengths for the Award:

Professor Dominique Heymann is a distinguished figure in the field of oncology, particularly bone oncology, with a strong focus on the molecular mechanisms of bone tumors like osteosarcoma. His academic and clinical roles at the University of Nantes and the ICO Cancer Centre underscore his leadership in research and patient care. He has contributed significantly to understanding tumor biology, bone remodeling, and regenerative medicine, making him a highly respected expert in these fields. His research addresses crucial topics such as circulating tumor cells, targeted therapies, and the development of new anticancer agents, all of which are of immense value to advancing cancer treatment. With multiple publications in prestigious journals, including studies on novel therapies and molecular pathways in cancer progression, Professor Heymann has demonstrated exceptional scientific rigor. His global collaborations and recognition further establish him as a leading researcher in cancer biology and oncology.

Areas for Improvements:

Despite his numerous contributions, there are a few areas where Professor Heymann’s research could evolve. While he has made notable strides in cancer treatment and bone oncology, expanding research into more personalized medicine approaches and exploring the integration of AI and machine learning in predictive oncology could enhance the applicability of his findings. Furthermore, increasing collaborative efforts with international interdisciplinary teams could yield broader insights, especially in rare cancers and metastasis research. Developing a more extensive outreach to clinical trials and collaborations in broader regions may also allow for faster translation of his research into practice.

Education:

Professor Heymann began his academic journey at Paris VII University, where he earned a Master’s degree in Cell Biology in 1991. His PhD in Cell Biology and Immunology was completed at Nantes University in 1995, a pivotal moment in his career. Further expanding his knowledge, he pursued research management abilities and a deeper focus on Biochemistry and Cell Biology at Nantes University in 1998. He also received specialized certification in Histology from Nantes University in 1999 and later completed the required authorizations for animal experimentation in 2003 and 2016. Throughout his academic career, Professor Heymann has continually updated his qualifications, ensuring his expertise remains at the cutting edge of medical and biological sciences. His academic foundation has underpinned his significant contributions to cancer research, with a strong emphasis on bone oncology and regenerative medicine.

Experience:

Professor Dominique Heymann has an extensive and diverse career spanning several decades in both academic and clinical settings. Currently, he serves as a Professor of Histology/Embryology at Nantes University and as a Hospital Practitioner at the ICO Cancer Centre, where he is instrumental in patient care and research. His professional trajectory includes significant roles in oncology, particularly focused on bone tumors, osteosarcoma, and regenerative medicine. As an Honorary Professor at the University of Sheffield, he extends his influence beyond France, fostering international collaboration in cancer research. Professor Heymann has been a prominent figure in multiple research projects, having managed and contributed to groundbreaking studies. His expertise in cancer biology, combined with his academic roles, has allowed him to mentor students and researchers, shaping the next generation of scientists. His dual role in academia and clinical practice makes him a leading figure in both spheres.

Awards and Honors:

Professor Dominique Heymann’s career is adorned with numerous accolades and honors. As a tenured professor at the University of Nantes, he has received recognition for his contributions to histology, embryology, and oncology. He was appointed as an Honorary Professor in Bone Oncology at the University of Sheffield, UK, an esteemed acknowledgment of his expertise in the field. His work in cancer research, particularly related to bone tumors, has earned him international recognition, and his published studies continue to be highly regarded in scientific journals. Additionally, Professor Heymann has contributed significantly to the understanding of osteosarcoma and bone regeneration, which has earned him awards from academic and clinical societies. His continuous impact in advancing the field through groundbreaking research, leadership in clinical oncology, and educational contributions has made him a highly respected figure in the medical and scientific communities.

Research Focus:

Professor Dominique Heymann’s research is focused on cancer, particularly bone tumors such as osteosarcoma, and the molecular mechanisms involved in bone regeneration. His work primarily investigates the signaling pathways that control bone remodeling, the interactions between tumor cells and the microenvironment, and the role of immune responses in bone diseases. One of his key research interests is the development of targeted therapies to combat cancer progression, with a special emphasis on novel anticancer agents, including glycosaminoglycan-mimetic compounds derived from marine bacterial exopolysaccharides. In addition, Professor Heymann is dedicated to studying the role of circulating tumor cells as predictive markers for drug resistance and tumor progression. His expertise also includes stem cell therapies, autophagy in osteoblasts, and the potential for therapeutic applications in bone repair and regeneration. His research aims to improve patient outcomes through innovative approaches in cancer treatment and bone health.

Publications Top Notes:

  • Heymann D, Muñoz-Garcia J, Babuty A, et al. A new promising anticancer agent: a glycosaminoglycan-mimetic derived from the marine bacterial infernan exopolysaccharide. Int J Biol Macromol. (in press) 🧬

  • Jacquot P, Muñoz-Garcia J, Léger A, et al. A multispecific checkpoint inhibitor Nanofitin with a fast tumor accumulation property and antitumor activity in immune competent mice. Biomolecules. (in press) 🔬

  • Yadav P, Heymann D, Prasad RN. Circulating tumor cells: a predictive marker for drug resistance and tumor progression. Front Oncol. (in press) 🔬

  • Muñoz-Garcia J, et al. Interleukin-34 orchestrates bone formation through its binding to Bone Morphogenic Proteins. Theranostics. 2025; 15(7):3185-3202. 🦴

  • Young RJ, et al. CIRCUS: CIRCUlating tumor cells in soft tissue Sarcoma – a short report. Cancer Drug Resist. 2022; 4:51. 💉

  • Oliver L, et al. Transcriptional landscape of the interaction of human mesenchymal stem cells with glioblastoma in bioprinted co-cultures. Stem Cell Res Ther. 2024; 15(1):424. 🧫

  • Cordova LA, et al. Why are osteoporosis patients treated with antiresorptive therapies considered like oncology patients regarding their oral health care? Osteoporos Int. 2024; 35(9):1677-1678. 🦷

  • Childs A, et al. A prospective observational cohort study for newly diagnosed patients in the UK: ICONIC study initial results. Cancers (Basel). 2024; 16(13):2351. 📊

  • Rey V, et al. A personalized medicine approach identifies enasidenib as an efficient treatment for IDH2 mutant chondrosarcoma. EBioMedicine. 2024; 102:105090. 🧬

  • Jubelin C, et al. Identification of MCM4 and PKRDC as new regulators of osteosarcoma cell dormancy based on 3D cultures. BBA Mol Cell Res. 2024; 1871:119660. 🧪

Conclusion:

Professor Dominique Heymann’s expertise in oncology, histology, and embryology positions him as an outstanding candidate for the Research for Best Researcher Award. His achievements in cancer research, particularly in bone tumors, and his contributions to advancing the understanding of tumor biology make him an exemplary figure. While there are areas to expand in terms of interdisciplinary collaborations and technological integration, his exceptional body of work and his dedication to both academic excellence and clinical practice make him a deserving candidate for this prestigious award.

Ayrton Bangolo | Cancer Cell Biology | Best Researcher Award

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Dr. Ayrton Bangolo | Cancer Cell Biology | Best Researcher Award

Dr. Ayrton Bangolo , Hackensack University Medical Center , United States

Ayrton I. Bangolo, MD, is an accomplished board-certified Internal Medicine physician specializing in Hematology and Oncology. He completed his MBBS (equivalent to MD) from Tianjin Medical University, China, in 2016 and is currently a Hematology and Oncology fellow at Hackensack University Medical Center, NJ. With an impressive record of research publications and contributions to several medical journals, he has a passion for advancing cancer care and the clinical aspects of various diseases. Dr. Bangolo is deeply involved in both clinical practice and research, having worked in multiple specialties and international medical settings. His expertise is enriched by his diverse experiences across different clinical environments, from hospitals in the United States to clinics in the Democratic Republic of the Congo. He holds a variety of leadership roles, demonstrating commitment to the global advancement of healthcare.

Publication Profile:

Google Scholar

Strengths for the Award:

Dr. Ayrton I. Bangolo’s exceptional contributions to the medical field make him a strong candidate for the “Best Researcher Award.” His work spans critical areas of oncology, including the impact of tumor stage and histopathology on survival outcomes in esophageal cancer, as well as his pioneering research on the gut microbiome’s role in pancreatic cancer treatment. His academic rigor is evident through his prolific research output and successful collaboration with international researchers. Additionally, Dr. Bangolo’s role as a peer reviewer for prominent medical journals underscores his expertise and respect in the medical community. His focus on racial, ethnic, and socioeconomic disparities in cancer care reflects his commitment to improving healthcare outcomes for underserved populations. Moreover, his ongoing research aims to bridge knowledge gaps in critical areas such as thyroid cancer management and gastrointestinal malignancies.

Areas for Improvement:

While Dr. Bangolo’s work is impressive, expanding his collaborative efforts to include more interdisciplinary research could enhance his scope even further. Although his focus on cancer disparities is commendable, there may be opportunities to expand his research into other areas of healthcare equity, such as mental health in cancer patients or global access to cancer treatments. Additionally, increasing involvement in clinical trials may provide real-world validation for his findings, leading to more practical applications in patient care.

Education:

Dr. Bangolo obtained his MBBS from Tianjin Medical University, Tianjin, China, in 2016, and has earned multiple certifications in the United States, including the ECFMG certification. He has successfully completed the USMLE exams, passing all steps (1, 2, and 3) on the first attempt. Dr. Bangolo is currently undergoing advanced training in Hematology and Oncology at Hackensack University Medical Center, NJ, in an ACGME-accredited fellowship program. His prior residency in Internal Medicine and a transitional year at Palisades Medical Center, North Bergen, NJ, has further honed his skills. Throughout his education, Dr. Bangolo has consistently demonstrated academic excellence and a commitment to evidence-based practice. His journey through diverse healthcare systems and international medical education reflects his dedication to global health improvement and patient-centered care.

Experience:

Dr. Bangolo has extensive clinical experience spanning multiple specialties, beginning with his externship and observership roles in Endocrinology, Nephrology, and Interventional Radiology. He served at Endocrine Associates in Louisville, KY, and worked with Dr. Hisham Alrefai in Endocrinology and Dr. Mohammed El Kheir in Nephrology. His residency in Internal Medicine at Palisades Medical Center, North Bergen, NJ, allowed him to build foundational skills in patient care and management across various medical conditions. Currently, he is completing an ACGME-accredited fellowship in Hematology and Oncology at Hackensack University Medical Center, where he continues to refine his expertise in treating complex cancer patients. Additionally, Dr. Bangolo has contributed to clinical research and presented at various academic conferences. His exposure to diverse medical environments, from the US to the Democratic Republic of the Congo, gives him a well-rounded perspective on healthcare delivery.

Awards and Honors:

Dr. Bangolo has received numerous awards and accolades, highlighting his outstanding contributions to the medical field. Among his notable recognitions is the 2nd Place for his original research poster on “Racial/Ethnic and Socioeconomic Differences in Colon Cancer Surgery Performed” during the HMH North Region Fellow/Residents Research Day. He was also involved in publishing open-access articles on significant public health issues, including the United Nations Sustainable Development Goals related to cancer treatment disparities. Dr. Bangolo’s work on ultrasound performance in the diagnosis of thyroid cancer earned recognition in the scientific community. His publications have made significant impacts, including in journals such as Breast Cancer Research and Treatment and World Journal of Gastroenterology. His consistent dedication to advancing medical knowledge, addressing healthcare disparities, and improving treatment outcomes has made him a respected figure in his field.

Research Focus:

Dr. Bangolo’s research primarily focuses on oncology, with a particular emphasis on cancer disparities, treatment outcomes, and innovative diagnostic methods. He has extensively studied the impacts of tumor stage and histopathology on survival outcomes in esophageal cancer and the influence of primary percutaneous coronary intervention on myocardial infarction outcomes. His work also includes investigating trends in thyroid cancer incidence, improving the understanding of gastrointestinal cancers, and exploring the role of the microbiome in pancreatic cancer. Dr. Bangolo is dedicated to researching the epidemiological factors that influence cancer outcomes in underserved populations, with a particular interest in racial, ethnic, and socioeconomic differences in treatment and survival. His ongoing research aims to improve treatment protocols and contribute to global cancer care, especially in resource-limited settings like the Democratic Republic of the Congo, where he has firsthand experience working.

Publications Top Notes:

  1. The Impact of Tumor Stage and Histopathology on Survival Outcomes in Esophageal Cancer Patients 📑
  2. Comprehensive Analysis of the Impact of Primary Percutaneous Coronary Intervention on Patients with ST-Segment Elevation Myocardial Infarction 💓
  3. Impact of American Thyroid Association’s Revised Cancer Management Guidelines on Thyroid Cancer Incidence Trends 📊
  4. Racial/Ethnic and Socioeconomic Differences in Colon Cancer Surgery Performed and Delayed Surgical Treatment 🎗️
  5. Ultrasound Performance Using the EU-TIRADS Score in the Diagnosis of Thyroid Cancer 🩺
  6. Epidemiologic Risk Factors for Chronic Pancreatitis and Pancreatic Ductal Adenocarcinoma 🦠
  7. Impact of Gut Microbiome in the Development and Treatment of Pancreatic Cancer 🧬
  8. Primary Cardiac Sarcoma: Clinical Characteristics and Prognostic Factors ❤️
  9. The Overall Quality of Evidence of Recommendations Surrounding Nutrition and Diet in Inflammatory Bowel Disease 🥗
  10. Outcomes of Patients with Gastrointestinal Stromal Tumors in the Past Decade 💉

Conclusion:

Dr. Ayrton I. Bangolo is undoubtedly a leading researcher in the field of oncology, with a robust academic and clinical background, significant contributions to medical literature, and a passion for addressing global healthcare disparities. His dedication to understanding complex diseases, combined with his focus on improving patient outcomes, positions him as a deserving candidate for the “Best Researcher Award.” Expanding his research to incorporate broader interdisciplinary efforts and clinical trials would further elevate his impact.