Vaclav Ranc | Cancer Cell Biology | Best Researcher Award

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Assoc. Prof. Dr. Vaclav Ranc | Cancer Cell Biology | Best Researcher Award

Assoc. Prof. Dr. Vaclav Ranc | Palacký University in Olomouc | Czech Republic

Dr. Václav Ranc is a distinguished analytical chemist and data analyst with over 15 years of experience in academia and applied research. Based in the Czech Republic, he leads a research group at Palacký University Olomouc, specializing in nanotechnology, plasmonic and electronic nanosensors, and advanced analytical techniques. He holds a Ph.D. in Analytical Chemistry and a Habilitation in Physical Chemistry. Dr. Ranc has published over 80 peer-reviewed scientific articles and holds several international patents. He has secured and managed significant EU funding, including Horizon Europe and MSCA projects, showcasing his excellence in both research and project leadership. His expertise spans Raman spectroscopy, mass spectrometry, and LC/GC methods, coupled with data analysis in Python, Matlab, and R. He is a regular presenter at international conferences and a recognized innovator in the fields of biosensing and nanomaterials.

Publication Profiles: 

Google Scholar
Orcid
Scopus

Education:

Dr. Václav Ranc earned his MSc. in Analytical Chemistry from Palacký University Olomouc (UPOL) in 2005, where he focused on the discrimination of enantiomers using mass spectrometry techniques such as LC-MS and CE-MS. He continued at UPOL to complete his Ph.D. in Analytical Chemistry, specializing in chiral analysis with HPLC-MS and GC-MS. His academic trajectory culminated in a Habilitation in Physical Chemistry, reflecting his advancements in Raman microscopy, SERS, and mass spectrometry. Dr. Ranc’s education is deeply rooted in analytical and physical chemistry, with a significant emphasis on developing and applying sophisticated separation and detection techniques for complex biological and clinical samples. His academic background is further enriched by international research experiences in Sweden and Switzerland, where he worked on electroanalytical techniques and nanoLC-MS applications for neurotransmitter analysis.

Experience:

Dr. Václav Ranc currently serves as the Head of a Research Group at Palacký University Olomouc, managing a 20-member team focused on cutting-edge nanomaterials and analytical chemistry. He has led the group’s scientific, financial, and personnel management, improving research output by 30%. Previously, he worked as a Research Assistant in Switzerland and at Palacký University, where he developed analytical techniques for clinical and neurological studies using mass spectrometry. His earlier roles include assisting in electrochemical method development at Lund University and clinical toxicology at Faculty Hospital Olomouc. His leadership extends to managing multimillion-CZK budgets and delivering impactful results in EU-funded research projects. Throughout his career, he has seamlessly combined academic excellence with innovation, leading to patented technologies and industrial prototypes, while mentoring young researchers and collaborating with international scientific networks.

Honors & Awards:

Dr. Václav Ranc has received several national and international honors for his scientific excellence. Notable among them is the Golden Medal at the International Invent Arena for the innovative KeyLock authentication system. He also earned the Bronze Prize from MERCK’s Young Analytical Chemists Competition and was a Finalist for the prestigious Shimadzu Prize for Young Analytical Chemists. His awards reflect consistent recognition for his groundbreaking work in analytical chemistry and applied nanotechnology. These accolades underscore his ability to translate complex research into practical applications, particularly in biosensing, authentication systems, and advanced materials. Dr. Ranc’s career is marked by impactful innovations that bridge academic research with industry needs, affirming his role as a thought leader in his field. His awarded projects and patents have contributed significantly to medical diagnostics, material sciences, and anti-counterfeiting technologies.

Research Focus:

Dr. Ranc’s research focuses on analytical chemistry, nanotechnology, and biosensing. He specializes in Raman spectroscopy (including SERS), LC/GC-MS, and the development of plasmonic and electronic nanosensors. His work bridges basic science and applied innovation, emphasizing the synthesis of nanoparticles, development of authenticity verification systems, and detection of biomarkers in clinical diagnostics. His contributions to surface-enhanced Raman spectroscopy have led to the development of patented methods and tools, including test strips and analytical systems. Dr. Ranc’s interdisciplinary approach combines analytical method development, data analysis using Python, R, and Matlab, and project management of EU-funded research. His current Horizon Europe projects focus on medical applications of nanotechnology, contributing to improved diagnostics, drug delivery systems, and authenticity verification. Through collaborations with European research institutions and industries, Dr. Ranc is pushing the boundaries of next-gen biomedical and analytical technologies.

Publication Top Notes:

  1. Magnetic 2D Transition-Metal-Based Nanomaterials in Biomedicine: Opportunities and Challenges in Cancer Therapy

  2. Highly Cytotoxic Copper(II) Mixed-Ligand Quinolinonato Complexes: Pharmacokinetic Properties and Interactions with Drug Metabolizing Cytochromes P450

  3. Graphene Oxide Nanoplatforms to Enhance Cisplatin-Based Drug Delivery in Anticancer Therapy

  4. Polymer-Based Graphene Derivatives and Microwave-Assisted Silver Nanoparticles Decoration as a Potential Antibacterial Agent

  5. New Limits for Stability of Supercapacitor Electrode Material Based on Graphene Derivative

  6. Label-free Determination of Prostate Specific Membrane Antigen in Human Whole Blood by Magnetically Assisted SERS

  7. Cyanographene and Graphene Acid: Emerging Derivatives Enabling High-Yield and Selective Functionalization of Graphene

  8. Detection of Prosthetic Joint Infection Based on Magnetically Assisted Surface Enhanced Raman Spectroscopy

  9. Functional Nanosheet Synthons by Covalent Modification of Transition-Metal Dichalcogenides

  10.  Nanoporous Nitrogen-Doped Graphene Oxide/Nickel Sulfide Composite Sheets for Hydrogen and Oxygen Evolution

Conclusion:

In conclusion, Dr. Václav Ranc is an exceptional candidate for the Best Researcher Award, demonstrating a rare synergy of academic excellence, applied innovation, and impactful leadership. His contributions to analytical chemistry and nanotechnology have advanced both scientific understanding and practical diagnostic solutions. His impressive publication record, international collaborations, patent portfolio, and success in leading multimillion-euro projects set him apart as a researcher of outstanding merit. With minor expansion into global research programs and commercialization efforts, Dr. Ranc is poised to further amplify his already significant impact. For his sustained contributions to science, his ability to lead and innovate, and his commitment to solving real-world problems through chemistry and nanotechnology, Dr. Václav Ranc is highly deserving of the Best Researcher Award.

Yanlan Wang | Cancer Cell Biology | Best Researcher Award

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Dr. Yanlan Wang | Cancer Cell Biology | Best Researcher Award

Dr. Yanlan Wang, Stanford, United States

Dr. Yanlan Wang is a distinguished postdoctoral research fellow at Stanford University’s Department of Pathology. She works in the esteemed Dr. Gerald Crabtree’s lab, where her research revolves around leveraging molecular glues to reprogram cancer drivers and trigger apoptosis. With a strong background in immuno-oncology, antibody engineering, and small molecule therapeutics, Dr. Wang has made significant contributions to targeted cancer therapies. Her interdisciplinary collaborations, notably with Dr. Nathanael Gray’s group, have explored the role of transcription factor complex-inducing compounds (TCIPs) in MLL-rearranged leukemia. Dr. Wang brings a rich international research experience from China and the U.S., with a career spanning translational medicine, biotechnology innovation, and academic excellence. She is known for her rigorous approach to scientific inquiry, collaborative spirit, and prolific publication record. Her passion for understanding and overcoming the mechanisms of cancer resistance positions her as a future leader in oncology drug development and precision medicine.

Publication Profile: 

Scopus

✅ Strengths for the Award:

  1. Outstanding Research Focus
    Dr. Wang’s work on molecular glues and transcription factor modulators represents cutting-edge approaches in cancer therapy, especially in targeting previously undruggable pathways.

  2. High Impact Publications
    With multiple first-author and co-corresponding author papers (e.g., J Immunol Methods 2025, Leukemia & Lymphoma 2020, Clin Pharmacol Ther 2021), Dr. Wang has demonstrated a strong track record in both fundamental and translational cancer research.

  3. Innovation & Translational Impact
    Her efforts in bispecific antibody engineering, IL-15 therapeutics, and AKR1C3-targeted prodrugs show clear applications in oncology drug development, bridging the lab and clinic.

  4. Prestigious Collaborations
    Collaborating with renowned researchers such as Dr. Gerald Crabtree and Dr. Nathanael Gray at Stanford indicates high confidence and integration in world-class research circles.

  5. Recognition & Awards
    She has received the Coxe Fellowship at Stanford and multiple merit-based scholarships, highlighting academic excellence and innovation.

  6. Leadership and Multidisciplinary Skills
    Dr. Wang has led several projects, authored high-level papers, and mentored junior researchers, showcasing both technical and leadership capability.

🔄 Areas for Improvement:

  1. Greater International Presentation Exposure
    Although she has strong publication credentials, more visibility through international oral presentations, keynote addresses, or panel roles would amplify her leadership profile.

  2. Independent Grant Record
    While she is currently in a postdoctoral role, seeking independent funding (e.g., K99/R00, early-career PI grants) would position her more competitively for independent investigator status.

  3. Patent or Commercial Translation
    Given the translational nature of her work, pursuit of intellectual property filings or biotech partnerships would further highlight impact.

🎓 Education:

Dr. Yanlan Wang began her academic journey at Xiangya School of Medicine, Central South University, where she earned her MBBS (M.D. equivalent) in June 2012. She continued at The Second Xiangya Hospital for her clinical residency, completing her M.S. in June 2015. Her pursuit of scientific excellence led her to earn a doctorate (M.D. equivalent to PhD) from Sun Yat-sen University in June 2018, with a research focus on microbial immunology and tumor biology. This diverse educational background gave her a solid foundation in both clinical medicine and biomedical research, allowing her to bridge translational gaps in cancer research. Her early training emphasized immunotherapy, molecular biology, and oncology, all of which paved the way for her postdoctoral work in cutting-edge labs. Her education reflects a consistent upward trajectory, marked by prestigious institutions, interdisciplinary training, and a seamless integration of clinical and scientific disciplines.

🔬 Experience:

Dr. Yanlan Wang is currently a postdoctoral research fellow in Dr. Gerald Crabtree’s lab at Stanford University, where she focuses on manipulating cancer cell pathways using molecular glues. Her prior research in China included pivotal roles in biotechnology innovation, including bispecific antibody engineering, prodrug design, and immune-oncology drug development. She has also collaborated extensively with Dr. Nathanael Gray’s lab at Stanford, exploring the therapeutic potential of TCIPs in leukemia. Dr. Wang’s hands-on experience includes multiplex screening platforms, flow cytometry, in vivo tumor models, and translational immunotherapy development. Over the years, she has taken leadership roles in preclinical projects, manuscript authorship, and international scientific presentations. Her diverse roles—from clinical residency to laboratory innovation—reflect her capability to translate complex scientific findings into therapeutic strategies. Dr. Wang has also mentored junior researchers and worked across multiple disciplines, underscoring her adaptability, leadership potential, and deep commitment to cancer research.

🏅 Awards and Honors:

Dr. Yanlan Wang’s excellence has been recognized through several prestigious awards. At Stanford, she received the Coxe Fellowship in 2021, honoring outstanding postdoctoral researchers. During her doctoral training, she earned the Special Award of Merit for the BJ-001 Project at BJ Bioscience Inc. in 2019 for her impactful translational research. Her academic merit was consistently acknowledged through the Bidi Scholarship (2016–2017) and Daxiang Scholarship (2015–2016) at Sun Yat-sen University. These honors underscore her commitment to scientific excellence, innovation, and translational impact in oncology and immunotherapy. Her ability to receive awards across both academic and industrial settings highlights her versatility and the real-world relevance of her work. These distinctions serve as a testament to her leadership in cancer drug development, collaborative effectiveness, and contribution to next-generation therapeutic discoveries.

🔍 Research Focus:

Dr. Yanlan Wang’s research lies at the intersection of cancer biology, molecular pharmacology, and immunotherapy. At Stanford, she investigates how molecular glues can be used to hijack cancer drivers and activate apoptosis, offering a novel route for targeted cancer therapies. Her work involves multiplex molecular glue screening, understanding protein degradation pathways, and designing synthetic lethality strategies. In collaboration with Dr. Nathanael Gray, she is also studying Transcription factor Complex-Inducing Compounds (TCIPs) for the treatment of MLL-rearranged leukemia, a particularly aggressive form of blood cancer. Prior to this, her research focused on bispecific antibodies, prodrugs, and IL-15 based immunotherapeutics, with a vision to decouple efficacy from toxicity. Through a blend of basic science and translational applications, she aims to rewire oncogenic signaling pathways and enhance anti-tumor immunity. Her research combines drug discovery, systems biology, and precision oncology, pushing the boundaries of targeted cancer treatment.

📚 Publications Top Notes:

  1. 🔬 Quantitative flow cytometry using quantitative streptavidin-protein G-biotin beads (qBeads) – J Immunol Methods, 2025

  2. 🧬 A Bivalent Molecular Glue Linking Lysine Acetyltransferases to Oncogene-directed Cell Death – Cell (revising)

  3. 💉 Enhance IL15 anti-tumor efficacy by inhibiting its negative feedback mechanism – (in preparation)

  4. ⚛️ Decouple the toxicity and efficacy of BJ-001, an integrin targeting IL-15 – AACR Abstract, 2019

  5. 🔄 Decoupling the toxicity and efficacy of immunotherapeutics – SITC Abstract, 2019

  6. 🧪 An AKR1C3-specific prodrug with potent anti-tumor activities against T-ALL – Leukemia & Lymphoma, 2020

  7. 🧫 A novel AKR1C3 specific prodrug TH3424 with potent anti-tumor activity in liver cancer – Clin Pharmacol Ther, 2021

  8. 🧲 A GPC3-targeting Bispecific Antibody, GPC3-S-Fab, with Potent Cytotoxicity – J Vis Exp, 2018

  9. 🧠 Identification of anti-CD16a single domain antibodies and their application in bispecific antibodies – Cancer Biol Ther, 2020

  10. 🧿 Bp-Bs, a novel T-cell engaging bispecific antibody with biparatopic Her2 binding – Mol Ther Oncolytics, 2019

  11. 🧰 A novel multi-functional anti-CEA-IL15 molecule displays potent anti-tumor activities – Drug Des Devel Ther, 2018

  12. 🧠 A single domain based anti-Her2 antibody has potent anti-tumor activities – Transl Oncol, 2018

🧾 Conclusion:

Dr. Yanlan Wang is highly deserving of the Best Researcher Award. Her contributions to cancer therapeutics through novel molecular approaches, her collaborations with globally renowned labs, and her publication record reflect a researcher of exceptional caliber and promise. With a deep understanding of tumor biology, a commitment to innovation, and a growing leadership presence in oncology research, she is not only suitable for the award but stands as a strong role model for future biomedical researchers.

Raul Valenzuela | Cancer Cell Biology | Best Researcher Award

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Assist. Prof. Dr. Raul Valenzuela | Cancer Cell Biology | Best Researcher Award

Assist. Prof. Dr. Raul Valenzuela , MD Anderson Cancer Center , United States

Dr. Raul F. Valenzuela Perez is a highly accomplished Assistant Professor of Musculoskeletal Imaging at The University of Texas MD Anderson Cancer Center. With over two decades of medical experience, he combines expertise in radiology, oncology, and advanced imaging techniques. Originating from Chile, Dr. Valenzuela earned his MD from Universidad de Chile and pursued advanced training in health administration and imaging sciences. His global perspective and collaborative research efforts have made him a prominent figure in musculoskeletal tumor imaging. He is board-certified in radiology in both the U.S. and Chile and is actively licensed in Texas and Florida. Dr. Valenzuela’s dedication to oncologic imaging, radiomics, and MRI innovations has resulted in numerous peer-reviewed publications, especially in the field of sarcoma imaging. Through ongoing work in developing and validating novel imaging biomarkers, he continues to shape the future of cancer diagnostics and personalized treatment approaches.

Publication Profile: 

Scopus

✅ Strengths for the Award:

  1. Prolific Research Output 📚
    Dr. Valenzuela has published extensively in high-impact journals like Scientific Reports, JCO Clinical Cancer Informatics, and Journal of Radiology & Oncology, with recent work in 2023–2025 focusing on radiomics, MRI biomarkers, and musculoskeletal oncology.

  2. Innovation in Imaging Techniques 💡
    He has pioneered the use of contrast-enhanced susceptibility-weighted imaging (CE-SWI) and quantitative diffusion-weighted MRI to evaluate soft tissue sarcomas and treatment response — advancing imaging beyond traditional RECIST criteria.

  3. Collaborative Multidisciplinary Work 🤝
    Dr. Valenzuela consistently co-authors with surgical oncologists, pathologists, and radiologists, highlighting his collaborative research approach that bridges disciplines.

  4. International Clinical Credibility 🌎
    He is licensed in the U.S. (Texas & Florida) and Chile, and board-certified in both American and Chilean radiology boards, reflecting his global expertise and trust in varied medical systems.

  5. Academic Leadership at MD Anderson 🎓
    As an Assistant Professor at one of the world’s top cancer centers, he contributes to education, clinical care, and high-level cancer imaging research.

⚙️ Areas for Improvement:

  1. Recognition and Awards Disclosure 🏅
    While the publication record is impressive, public listing of prior individual awards, fellowships, or grants would strengthen his profile further for award consideration.

  2. Principal Investigator Roles 🧪
    Although highly involved in collaborative projects, leading major multi-center trials or imaging consortia as principal investigator would elevate his leadership status.

  3. Expanded Public Science Communication 🗣️
    Increasing outreach via conferences, keynote talks, or educational platforms (like webinars or radiology workshops) could enhance his visibility in the broader scientific community.

🎓 Education:

Dr. Raul F. Valenzuela Perez holds an MD from Universidad de Chile (1993), where he laid the foundation for his distinguished medical and academic career. Alongside his medical training, he pursued further specialization in healthcare management, earning two certificates from the University of Chile Business School: one in Business and Health Administration (2003) and another in Process Management and Health Administration (2005). This unique blend of medical and administrative education empowers Dr. Valenzuela with a strategic understanding of healthcare systems and leadership. His academic journey highlights a commitment to continuous learning and cross-disciplinary excellence. As a thought leader in radiologic sciences, Dr. Valenzuela has integrated his business knowledge with clinical expertise to enhance imaging workflows and patient-centered care, especially in high-impact cancer institutions like MD Anderson. His education reflects both clinical proficiency and managerial insight, laying the groundwork for his contributions to musculoskeletal oncology imaging.

🏥 Experience:

Since September 2019, Dr. Valenzuela has served as an Assistant Professor in Musculoskeletal Imaging at The University of Texas MD Anderson Cancer Center, one of the world’s leading cancer research institutions. Prior to his tenure in the U.S., he developed a robust clinical background in Chile, where he practiced and taught radiology. With licenses from the Texas Medical Board, Florida Medical Board, and Chilean Medical Association, his clinical credentials span internationally. He is also certified by the American Board of Radiology and the Chilean Radiology Board. At MD Anderson, Dr. Valenzuela plays a key role in advancing diagnostic imaging for musculoskeletal tumors, particularly soft tissue sarcomas. His responsibilities include patient care, teaching, research, and contributing to the development of advanced imaging protocols. Known for his collaborative style and interdisciplinary approach, he is a respected mentor and a valued contributor in the field of cancer imaging.

🏅 Awards and Honors:

While specific named awards are not detailed in the provided data, Dr. Raul F. Valenzuela Perez’s growing publication record, leading research in radiomics, and collaborative work at MD Anderson suggest a strong reputation in his field. His continuous publication in high-impact journals, such as Scientific Reports, JCO Clinical Cancer Informatics, and Journal of Radiology & Oncology, indicate recognition by peers and ongoing contributions to advancing cancer imaging. His role in multidisciplinary research teams and innovative use of advanced MRI techniques position him as a strong candidate for awards like Best Researcher. His efforts in improving imaging criteria beyond RECIST and validating AI-based radiomic frameworks show both vision and leadership. Though a detailed list of awards isn’t cited, his contributions to musculoskeletal oncology, particularly in sarcoma treatment response evaluation, reflect a track record of academic excellence and clinical impact, meriting honor and distinction in his specialty.

🔬 Research Focus:

Dr. Valenzuela’s primary research focus lies in advanced imaging for musculoskeletal oncology, particularly the integration of radiomics, perfusion-weighted MRI, and contrast-enhanced susceptibility-weighted imaging (CE-SWI) for tumor characterization and treatment monitoring. His work is centered on improving diagnosis and predicting response in soft-tissue sarcomas, such as undifferentiated pleomorphic sarcoma (UPS) and desmoid fibromatosis. He actively collaborates on multi-institutional studies, applying quantitative imaging biomarkers and AI-driven radiomic models to identify tumor behavior patterns and personalize therapy. A key aspect of his research is the evaluation of multiparametric MRI features, including diffusion-weighted and dynamic contrast-enhanced imaging. His publications reveal a commitment to pushing boundaries in functional imaging and improving imaging response criteria beyond traditional RECIST methods. Through his research, Dr. Valenzuela aims to contribute to precision medicine in oncology, bridging radiology and data science to enhance patient outcomes and streamline therapeutic decision-making.

📚 Publications Top Notes:

  1. 🧠 Perfusion-weighted imaging features predicting UPS treatment response – Sci Rep, 2024

  2. 🧬 Radiomics by diffusion-weighted MRI for extremity UPS prediction – J Radiol Oncol, 2024

  3. 🧲 Contrast-enhanced SWI for musculoskeletal oncologic pathology – J Radiol Oncol, 2024

  4. 💉 Perfusion imaging of the musculoskeletal system – Magn Reson Imaging Clin N Am, 2024

  5. 🤖 Cancer radiomic and perfusion imaging automated framework – JCO Clin Cancer Inform, 2024

  6. 🧠 Idiopathic intracranial hypertension: MRI vs venous sinus pressure – Rev Chil Radiol, 2023

  7. 📊 CE-SWI in desmoid fibromatosis response assessment – Tumor Discov, 2023

  8. 📈 Multiparametric MRI for treatment and recurrence in sarcoma – J Radiol Oncol, 2023

  9. 🔍 ADC map-based radiomics for sacral tumor differentiation – JCO Precis Oncol, 2023

  10. 📐 Advanced imaging in musculoskeletal oncology (ABASTI Part I) – Semin Ultrasound CT MR, 2021

  11. 🧪 Radiomic features of CE-SWI in UPS treatment response – JCO Clin Cancer Inform, 2025

📝 Conclusion:

Dr. Raul F. Valenzuela Perez is a highly deserving candidate for the Best Researcher Award. His innovative contributions to musculoskeletal oncologic imaging, especially in applying radiomic models and advanced MRI techniques, place him at the forefront of translational cancer imaging. His interdisciplinary collaborations and growing body of work have strong clinical impact, particularly for sarcoma management.

With additional visibility through PI roles and recognition through formal honors, Dr. Valenzuela’s already impressive profile is on a trajectory toward international distinction. Based on the current accomplishments and ongoing impactful research, he is highly recommended for this award.