Chen Huang | Cellular Bioenergetics Metabolism | Best Researcher Award

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Dr. Chen Huang | Cellular Bioenergetics Metabolism | Best Researcher Award

Dr. Chen Huang , Shenzhen Institute of Advanced Technology (SIAT) Chinese Academy of Sciences (CAS) , China

Dr. Chen Huang is an Associate Researcher at the Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences. She earned her Ph.D. in 2018 from the University of the Chinese Academy of Sciences. Her primary research lies at the intersection of female reproductive endocrinology and metabolic diseases, focusing on how adverse intrauterine environments impact long-term offspring health. Dr. Huang has authored over 20 SCI-indexed papers and holds 18 published patents with one under review. She has played significant roles in national and regional projects funded by the NSFC and Shenzhen Innovation Commission. Her notable contributions include identifying novel peptides with therapeutic potential in NAFLD and TNBC, and exploring molecular mechanisms behind pregnancy complications. Her impactful work, especially on metabolitin (MTL) and chemerin/GPR1 signaling pathways, has earned recognition in high-impact journals like Journal of Hepatology. Dr. Huang’s commitment to translational research places her at the forefront of biomedical innovation in women’s health.

Publication Profile:

Scopus

Strengths for the Award:

Dr. Chen Huang exemplifies academic and scientific excellence through her impactful research in the fields of female reproductive endocrinology and metabolic diseases. Her contributions have led to meaningful advancements in understanding the molecular mechanisms that govern maternal-fetal health and associated disorders such as NAFLD, pregnancy complications, and cancer.

Key strengths include:

  • Scientific Innovation: She has identified and characterized novel peptide hormones such as metabolitin (MTL) and explored their therapeutic roles, a groundbreaking approach in targeting metabolic and oncological diseases.

  • High-Quality Publications: With around 20 SCI-indexed journal articles, including those in high-impact journals like Journal of Hepatology and Molecular Therapy – Oncolytics, her work is widely recognized in the scientific community.

  • Patent Portfolio: Dr. Huang has published 18 patents, with another under review, demonstrating her strong translational focus and commitment to real-world biomedical applications.

  • Research Leadership: She has successfully led multiple competitive national and regional research projects funded by the NSFC and Shenzhen Innovation Commission.

Areas for Improvement:

While Dr. Huang’s research output and contributions are impressive, certain enhancements could further elevate her global profile:

  • International Exposure: Engaging in more international collaborative projects or joint publications with global institutes could broaden the impact of her research.

  • Editorial and Professional Roles: Participation in editorial boards, peer review panels, or scientific committees would enhance her leadership presence in the scientific ecosystem.

  • Industry Engagement: Establishing collaborations with biotech or pharmaceutical industries could increase the translational value of her work and open pathways for clinical applications.

🎓 Education:

Dr. Chen Huang received her Ph.D. in 2018 from the University of the Chinese Academy of Sciences. Her doctoral research laid the foundation for her interest in female reproductive endocrinology and metabolic disorders, combining clinical insight with molecular research. Throughout her academic training, she focused on identifying the mechanistic links between endocrine disruptions during pregnancy and their long-term effects on offspring health. She has continually built upon this expertise through advanced training and interdisciplinary collaborations. Her educational background provided her with a robust understanding of molecular biology, endocrine physiology, and metabolic pathways, which she has applied in various research contexts—from liver disease to cancer biology. Her academic excellence was further highlighted by her early co-first authorship in high-impact journals during her Ph.D., demonstrating her ability to lead and innovate in collaborative research projects even in early stages of her career.

🧪 Experience:

Dr. Chen Huang is currently serving as an Associate Researcher at the Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences. Since completing her Ph.D. in 2018, she has led and contributed to several key research projects, including those funded by the National Natural Science Foundation of China and the Shenzhen Science and Technology Innovation Commission. Her experience spans both basic and translational science, with an emphasis on hormonal regulation and metabolic diseases during pregnancy. She has collaborated with renowned scientists like Dr. Teng and Dr. Enkui Duan, contributing to the discovery of new peptide hormones such as metabolitin (MTL). Her professional experience is enriched by her ability to translate complex molecular findings into therapeutic strategies, especially in contexts like NAFLD and triple-negative breast cancer. With over 20 peer-reviewed SCI publications, her work reflects a consistent commitment to advancing biomedical research with clinical relevance.

🔬 Research Focus:

Dr. Chen Huang’s research focuses on the molecular underpinnings of female reproductive endocrinology and metabolic diseases, particularly within the context of pregnancy. She investigates how adverse intrauterine environments affect fetal development and contribute to long-term health issues in offspring. Her work explores key hormone-receptor interactions, such as the role of novel peptides (e.g., metabolitin) in liver disease and cancer. A major thread of her research also addresses the function of adipokines and their signaling pathways in pregnancy complications such as miscarriage and preeclampsia. Using both in vivo and in vitro models, she studies the regulatory mechanisms of trophoblast invasion, spiral artery remodeling, and immune cell interactions in the placenta. Her work integrates endocrinology, immunology, and developmental biology to identify new therapeutic targets. With an h-index of 12, she is recognized for her impactful publications and innovation in peptide-based treatments.

📚 Publications Top Notes:

  1. 🧬 Metabolitin (MTL) as a GPRC6A ligand improves NAFLD – Journal of Hepatology, 2020 (Co-first author)

  2. 🧪 Peptide blocks chemerin/GPR1 signaling to inhibit TNBC growth – Molecular Therapy – Oncolytics, 2020 (First author)

  3. 🔍 Adipokine promotes placental trophoblast invasion and vascular remodeling – Am J Physiol-Endocrinol Metab, 2019 (Co-first author)

  4. 🔬 mTOR hypoactivity causes trophectoderm failure via lysosomal activation – Cell and Bioscience, 2023

Conclusion:

Dr. Chen Huang is a highly deserving candidate for the Best Researcher Award. Her research contributions stand out in both innovation and societal impact, especially in the crucial domains of reproductive health and metabolic diseases. With a consistent publication record, numerous patents, and demonstrated research leadership, she is poised to make even greater scientific contributions in the years ahead. Recognizing her with this a

Tian Lan | Metabolic diseases | Best Researcher Award

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Prof Tian Lan | Metabolic diseases | Best Researcher Award

Prof Tian Lan ,  Harbin Medical University , China

Prof. Tian Lan is a leading researcher in molecular pharmacology at Harbin Medical University, China. With over 20 completed and ongoing research projects, his work primarily addresses metabolic diseases such as fatty liver, diabetes, and cardiovascular disorders. Prof. Lan is widely recognized for his innovative approaches to drug development, which aim to improve patient outcomes through novel pharmacological targets. He has published over 60 articles in prestigious journals, contributed to multiple patents, and collaborated with esteemed institutions like UC San Diego. His dedication to advancing medical knowledge and practice has garnered him significant citations, reflecting his impactful contributions to the field. Prof. Lan’s work embodies a blend of rigorous scientific research and practical applications, positioning him as a prominent figure in the study of metabolic diseases.

Publication profile

Scopus

Strengths for the Award

Prof. Tian Lan demonstrates exceptional expertise in molecular pharmacology, particularly in the realm of metabolic diseases. His prolific output includes over 60 publications in high-impact journals, a citation index exceeding 4000, and numerous ongoing and completed research projects (20+). His innovative research has led to the identification of new pharmacological targets and the development of novel therapeutic strategies, particularly for conditions like fatty liver disease and diabetes. Notable contributions include significant findings on GSTM2 and its role in metabolic disorders, as well as advancements in understanding cordycepin’s mechanisms. His collaborative work with prestigious institutions like UC San Diego showcases his ability to foster partnerships that enhance research impact.

Areas for Improvement

While Prof. Lan has made significant strides in research, enhancing public outreach and engagement with the broader community could amplify the impact of his findings. Increased participation in conferences and workshops to disseminate knowledge more widely could also benefit both his research visibility and collaborations.

Education 

Prof. Tian Lan earned his PhD in Molecular Pharmacology from a prestigious institution, where he developed a strong foundation in pharmacological research and therapeutic strategies. His education was characterized by a rigorous curriculum that combined both theoretical knowledge and practical laboratory skills. He pursued postdoctoral studies that further enhanced his expertise in metabolic diseases, focusing on the interplay between pharmacology and cellular mechanisms. His academic journey included extensive training in advanced research methodologies, allowing him to investigate complex biological systems and their responses to pharmacological interventions. Prof. Lan’s commitment to continuous learning has led him to engage in various workshops and conferences, where he has remained abreast of the latest developments in pharmacology and related fields. This educational background has been instrumental in shaping his research focus and methodology, ultimately contributing to his success as a researcher and educator.

Experience 

Prof. Tian Lan has extensive experience in both academic and research environments, contributing significantly to the field of molecular pharmacology. He has led numerous research projects at Harbin Medical University, focusing on drug development for metabolic diseases. With over 60 publications in high-impact journals, his research has been widely cited, reflecting his influence in the scientific community. Prof. Lan has also engaged in consultancy projects, collaborating with industry partners to translate research findings into practical applications. His editorial appointments in reputable journals further underscore his expertise and leadership within the field. Additionally, he has fostered collaborations with renowned institutions like the Chinese University of Hong Kong and UC San Diego, enhancing the scope and impact of his work. His participation in professional organizations, such as AASLD and ADA, highlights his commitment to ongoing professional development and contribution to advancing research in metabolic diseases.

Research Focus

Prof. Tian Lan’s research is centered on the molecular pharmacology of metabolic diseases, particularly focusing on fatty liver disease, diabetes, gout, and cardiovascular disorders. His innovative studies aim to uncover new pharmacological targets and develop novel therapeutic strategies that address these pressing health issues. By exploring the mechanisms behind metabolic dysfunction, Prof. Lan has made significant contributions to understanding how various pathways, such as the MAPK and ASK1 signaling pathways, can be modulated to improve disease outcomes. His work with glutathione S-transferase Mu2 (GSTM2) and cordycepin has revealed potential therapeutic targets that mitigate metabolic disorders and inflammatory damage. Furthermore, his research on traditional Chinese medicine and its integration with Western pharmacology showcases his commitment to a holistic approach in treatment. Overall, Prof. Lan’s focus on molecular mechanisms and drug development positions him at the forefront of advancing therapeutic options for metabolic diseases.

Publications Top Notes

  1. Qi Nan agarwood restores podocyte autophagy in diabetic kidney disease by targeting EGFR signaling pathway 📄
  2. Integrated traditional Chinese and Western medicine in the prevention and treatment of non-alcoholic fatty liver disease: future directions and strategies 📄
  3. Role of Gut Microecology in the Pathogenesis of Drug-Induced Liver Injury and Emerging Therapeutic Strategies 📄
  4. Fufang Zhenzhu Tiaozhi polysaccharides ameliorates high-fat diet-induced non-alcoholic steatohepatitis and intestinal flora disorders in mice 📄
  5. A Systematic Review of Statins for the Treatment of Nonalcoholic Steatohepatitis: Safety, Efficacy, and Mechanism of Action 📄
  6. Tianhuang formula ameliorates liver fibrosis by inhibiting CCL2-CCR2 axis and MAPK/NF-κB signaling pathway 📄
  7. Arbutin ameliorates liver fibrosis in mice by inhibiting macrophage recruitment and regulating the Akt/NF-κB and Smad signaling pathways 📄
  8. FTZ polysaccharides ameliorate kidney injury in diabetic mice by regulating gut-kidney axis 📄
  9. Glaucocalyxin A attenuates carbon tetrachloride-induced liver fibrosis and improves the associated gut microbiota imbalance 📄

Conclusion

Prof. Tian Lan’s robust research portfolio, significant contributions to pharmacology, and commitment to advancing our understanding of metabolic diseases position him as a leading candidate for the Best Researcher Award. His work not only contributes to academic knowledge but also holds the potential for substantial clinical applications, ultimately improving patient outcomes in metabolic health. Recognizing his achievements with this award would validate his impact on the field and inspire further innovation in research.