Jie Feng | Microbial Cell Biology | Best Researcher Award

Dr. Jie Feng | Microbial Cell Biology | Best Researcher Award

Dr. Jie Feng , Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences , China

Dr. Jie Feng is a distinguished researcher with significant contributions in the fields of edible fungi, biotechnology, and bioactive compounds, particularly focusing on the production and application of polysaccharides from medicinal mushrooms like Ganoderma lucidum. With a background in food chemistry and microbiology, Dr. Feng’s work bridges the gap between traditional medicine and modern industrial applications. He has developed innovative submerged fermentation techniques to improve the production of high molecular weight polysaccharides, optimizing their bioactivity for medical, nutritional, and functional food industries. His interdisciplinary research integrates microbiological methods with biotechnology, contributing to more efficient and scalable production processes. With a collaborative spirit, Dr. Feng has worked extensively with institutions across China and abroad, fostering international research partnerships. His work is widely recognized for its potential in enhancing the nutritional value and therapeutic properties of fungi-derived products, improving human health globally.

Publication Profile:

Google Scholar

Strengths for the Award:

  1. Innovative Approach: The research on innovative submerged directed fermentation for producing high molecular weight polysaccharides from Ganoderma lucidum (GLPs) demonstrates a significant advancement in the production of bioactive compounds with consistent quality. The focus on directed fermentation to improve yields and polysaccharide structure showcases an innovative approach in the field of food chemistry and biotechnological applications.
  2. Relevance and Market Impact: The study is highly relevant to the growing demand for functional ingredients and bioactive compounds from Ganoderma lucidum, especially in pharmaceuticals and functional foods. It addresses industry challenges such as low yield, unstable quality, and long cultivation times in traditional methods. The ability to produce high MW polysaccharides efficiently through submerged fermentation is an essential breakthrough for large-scale applications.
  3. Strong Multi-Disciplinary Expertise: The authors come from a range of institutions (Shanghai Academy of Agricultural Sciences, University of Shanghai for Science and Technology, and the Institute of General and Physical Chemistry in Belgrade), showing the successful collaboration of experts in food microbiology, fermentation science, chemistry, and biotechnology. This interdisciplinary teamwork strengthens the credibility and quality of the research.
  4. Contribution to Bioactivity Understanding: The research contributes to the deeper understanding of the structure-function relationships of GLPs, particularly the immunostimulatory effects of the β-glucan polysaccharides. This opens doors for further investigations into the therapeutic potential of Ganoderma lucidum.
  5. Impact on Biotechnological Production: The controlled conditions of submerged fermentation could offer a more reliable, scalable, and efficient method to produce high-quality polysaccharides for diverse applications, especially in the pharmaceutical and functional food industries.

Areas for Improvement:

  1. Long-Term Stability and Variability: While the research focuses on improving the consistency of high molecular weight polysaccharides, it would be beneficial to explore the long-term stability of the production system and any batch-to-batch variability that could affect commercial scalability. Further exploration of how fermentation scale impacts long-term product stability would be important for real-world industrial applications.
  2. Environmental and Economic Considerations: In an industrial setting, the economic viability and environmental impact of submerged fermentation should be explored further. Incorporating life cycle assessments or a comparison of the economic aspects (e.g., cost-efficiency, energy consumption) of submerged fermentation versus traditional cultivation could provide a more comprehensive analysis of the approach’s benefits.
  3. Further Structural Elucidation of Polysaccharides: The study briefly mentions the structural aspects of the polysaccharides (β-glucan backbone), but further detailed analysis of the molecular configuration and any possible modifications during fermentation could provide additional insights into their bioactivity and potential for therapeutic use.
  4. Exploring Broader Applications: Expanding the research to explore how the produced GLPs interact with other bioactive compounds or their broader applications in nutrition and functional foods could enhance the scope of the work. It could also lead to exploring synergistic effects in combination with other ingredients in the food or pharmaceutical industries.

Education:

Dr. Jie Feng holds a Ph.D. in Food Science from Shanghai Academy of Agricultural Sciences, China, where he specialized in the biotechnology of edible fungi and fermentation processes. Before obtaining his doctoral degree, he completed his Master’s in Microbiology from the University of Shanghai for Science and Technology, focusing on the optimization of microbial fermentation. Throughout his academic journey, Dr. Feng demonstrated a keen interest in microbiology, biotechnology, and food chemistry, working on various projects that explored the bioactive properties of polysaccharides and their applications in functional foods. His doctoral research laid the foundation for innovative submerged fermentation processes for producing high molecular weight polysaccharides. His education reflects a deep understanding of both the theoretical and practical aspects of microbiology and biotechnological applications in food production, setting him apart as an expert in his field.

Experience:

Dr. Jie Feng has a rich academic and research experience in the fields of food science and biotechnology. He has worked as a lead researcher at the Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences, where he led groundbreaking projects on the production of high molecular weight polysaccharides from Ganoderma lucidum. In addition to his work in submerged fermentation, Dr. Feng has also contributed to the advancement of biotechnological methods for improving the nutritional and bioactive properties of medicinal mushrooms. His work has been recognized internationally for its impact on functional food development and the medical industry. As a collaborator, Dr. Feng has worked with institutions like the University of Shanghai for Science and Technology and the Institute of General and Physical Chemistry, Belgrade, Serbia. His experience extends to both laboratory research and applied industrial processes, making him a versatile scientist and leader in his field.

Research Focus:

Dr. Jie Feng’s primary research focus is on the biotechnological production of high molecular weight polysaccharides from medicinal fungi, particularly Ganoderma lucidum. His work emphasizes submerged fermentation, a method that allows for precise control over the growth conditions of fungi, enabling the production of structurally defined bioactive polysaccharides. These polysaccharides are of great interest for their potential applications in pharmaceuticals, nutraceuticals, and functional foods. Dr. Feng’s research also investigates the optimization of fermentation parameters such as pH, nutrient supply, and oxygen levels to improve yield and consistency, addressing challenges faced in traditional cultivation methods. His work in the molecular structure and bioactivity of polysaccharides has implications for improving immune response and gut health, along with broader medicinal benefits. Additionally, Dr. Feng’s research aims to enhance the sustainability and scalability of polysaccharide production for industrial applications, making his research pivotal in the fields of functional foods and biotechnology.

Publications Top Notes:

  1. “Innovative Submerged Directed Fermentation: Producing High Molecular Weight Polysaccharides from Ganoderma lucidum” 🍄🔬
  2. “Regulation of Enzymes and Genes for Polysaccharide Synthesis in Ganoderma lucidum” 🧬🍄
  3. “Optimization of Submerged Fermentation for Ganoderma lucidum Polysaccharides” ⏱️🍄
  4. “Improving Immunostimulatory Effects of Ganoderma lucidum Polysaccharides” 💪🍄
  5. “Co-culture Fermentation of Ganoderma lucidum and Beneficial Microorganisms” 🤝🍄
  6. “Enhancing Quality and Yield of Functional Foods from Ganoderma lucidum” 🥗💊
  7. “Fermentation Process Development for Industrial-Scale Production of Polysaccharides” 🏭🔬

Conclusion:

The research on innovative submerged directed fermentation for producing high molecular weight polysaccharides from Ganoderma lucidum represents a significant step forward in the bioengineering of functional ingredients. It provides a reliable, scalable method for producing bioactive compounds with consistent quality, directly addressing challenges in the production of GLPs. The integration of various expertise from the fields of microbiology, food chemistry, and biotechnology enhances the credibility and applicability of the research. While there are areas for improvement, especially in terms of long-term scalability, economic analysis, and further structural elucidation, the work has great potential to influence both industrial practices and the broader scientific community.

 

 

 

 

Mai Kadry | Biochemistry | Best Researcher Award

Assist. Prof. Dr. Mai Kadry | Biochemistry | Best Researcher Award

Assist. Prof. Dr. Mai Kadry  , NRC , Egypt

Dr. Mai Osman Mohamed Kadry is an Assistant Professor at the Therapeutic Chemistry Department of the National Research Centre in Egypt, specializing in molecular and biochemical research. With over two decades of experience, she has contributed significantly to the advancement of therapeutic chemistry. Dr. Kadry obtained her PhD in Biochemistry from Cairo University in 2016, focusing on oxidative injury mitigation through antioxidants. She has authored and co-authored multiple articles in prestigious journals. Her research is driven by a passion for finding therapeutic solutions to biochemical challenges, with a focus on molecular mechanisms and drug development.

Publication Profile:

Scopus

Strengths for the Award:

Dr. Mai Osman Mohamed Kadry has made significant contributions to the field of therapeutic chemistry, particularly in molecular and biochemical research. As an Assistant Professor at the National Research Centre (NRC), her dedication to scientific advancement is evident in her research on oxidative stress, drug-induced toxicity, and the potential of nanotechnology to mitigate such effects. Her work has been published in high-impact journals, showcasing her expertise in areas like cancer research, biochemistry, and drug development. Additionally, her comprehensive teaching experience in academic settings has strengthened her ability to impart knowledge to the next generation of researchers.

Areas for Improvement:

Although Dr. Kadry’s work is impressive, her research could further benefit from exploring more collaborative projects across different research centers and incorporating a broader range of interdisciplinary approaches. Engaging with cutting-edge technologies such as AI-driven drug discovery or multi-omics data analysis could significantly expand her impact on therapeutic chemistry.

Education:

Dr. Mai Kadry’s academic journey began with a Bachelor’s degree in Pharmaceutical Sciences from Ain Shams University, graduating with honors in 2003. She later pursued an MSc in Pharmaceutical Sciences with a focus on Biochemistry from Helwan University in 2008. Her doctoral research at Cairo University led to a PhD in Biochemistry in 2016, where she studied the amelioration of oxidative stress induced by titanium dioxide nanoparticles in mice. This educational foundation has equipped her with a robust understanding of biochemistry, molecular biology, and drug therapy.

Experience:

Dr. Mai Kadry has a distinguished career at the National Research Centre (NRC) in Egypt, starting as an Assistant Researcher in 2004 and advancing to Assistant Professor in 2021. Over the years, she has contributed to groundbreaking research in therapeutic chemistry, particularly in the area of oxidative stress and drug toxicity. Dr. Kadry has also taught pharmacognosy at the Faculty of Pharmacy, 6 October University, and served on committees focusing on academic development. Her extensive teaching and research experience positions her as a leader in her field.

Research Focus:

Dr. Mai Kadry’s research focuses on therapeutic chemistry, exploring the molecular mechanisms of drug-induced toxicity, oxidative stress, and potential protective treatments. Her work investigates the impact of nanomaterials like titanium dioxide and their effects on cellular pathways. She also studies the synergistic potential of natural compounds to mitigate damage from toxins, using advanced biochemical methods to evaluate their efficacy. Additionally, Dr. Kadry has a keen interest in cancer research, focusing on autophagy signaling and the development of novel drug formulations.

Publications Top Notes:

  • “Titanium nanostructure mitigating doxorubicin-induced testicular toxicity in rats via regulating major autophagy signaling pathways” 🧬💉
  • “Inflammatory mediators-induced DNA damage in liver and brain injury: Therapeutic approach of 5-Methoy-N-acetyltryptamine” 🧠💊
  • “Necroptosis and autophagy in cisplatinum-triggered nephrotoxicity: Novel insights regarding their prognostic and diagnostic potential” 💊🩺
  • “Resveratrol-based nano-formulations as an emerging therapeutic strategy for ovarian carcinoma” 🎗️💡
  • “miR-122-IGF-1R signaling allied through the dysregulated lncRNA MALAT-1 expression in gastric carcinoma” 🧬🦠
  • “Reciprocal crosslink among MeCP2/BDNF/CREB signaling pinpointed in autism spectrum disorder” 🧠🔬
  • “CRISPR-Cas9 genome and long non-coding RNAs as a novel diagnostic index for prostate cancer therapy” 🧬🧬
  • “Collaboration of Hprt/K-RAS/c-Myc mutation in the oncogenesis of T-lymphocytic leukemia” 🩸⚗️
  • “Thioctic acid shield against lipopolysaccharide depression and endoplasmic reticulum stress: GR7M/Homer/ATF6 signaling” 🧬🛡️
  • “Titanium dioxide nanostructure-loaded Adriamycin surmounts resistance in breast cancer therapy” 🧬🎗️

Conclusion:

Dr. Mai Osman Mohamed Kadry stands out as an exemplary researcher in her field. Her focus on therapeutic chemistry, particularly in relation to oxidative stress, toxicity, and nanotechnology, positions her as a promising candidate for the Researcher of the Year Award. Through her continued contributions and potential for further interdisciplinary collaboration, she will likely continue to make pivotal advancements in the field of molecular and biochemical research.

 

 

 

Esmail El-Fakharany | cell biology | Best Researcher Award

Prof. Esmail El-Fakharany | cell biology | Best Researcher Award

Prof. Esmail El-Fakharany  , city of scientific research and technological applications , Egypt

Dr. Tamer Abdelrazik is a distinguished researcher in the field of biological sciences and biotechnology, specializing in microbiology, virology, and the preparation of therapeutic agents. He has contributed significantly to the scientific community with over 102 published papers and 16 book chapters. Dr. Abdelrazik holds an esteemed academic position as a part-time research fellow at Pharos University in Alexandria and the Pharmaceutical and Fermentation Industries Development Centre (PFIDC), Alexandria, Egypt. He is also recognized for his leadership as the principal investigator of several funded research projects, focusing on COVID-19 treatments, cancer therapeutics, and environmental technologies. Dr. Abdelrazik’s academic and research achievements have led to his recognition in Stanford’s ranking of the top 2% of impacting scientists globally.

Publication Profile:

Orcid

Strengths for the Award:

Dr. Tamer Abdelrazik demonstrates exceptional research achievements in the fields of biological sciences, biotechnology, and applied biomedical sciences. His impressive track record includes over 102 journal papers and 16 book chapters, with significant contributions to the understanding of antimicrobial agents, cancer therapies, and novel drug delivery systems. Notably, his leadership on projects like “Lactoferrin-Zinc nanocombinations for COVID-19” reflects his innovative approach in addressing global health challenges. Additionally, his inclusion in Stanford’s top 2% ranking of impacting scientists for 2023 showcases his prominence and impact in scientific research. His high H-index (28) and academic supervision of 9 M.Sc. and 13 Ph.D. students highlight his dedication to advancing research and mentoring future scientists.

Areas for Improvement:

While Dr. Abdelrazik’s research output is impressive, expanding the scope of his studies into other emerging fields such as AI-driven drug discovery or sustainability in biomedical engineering could strengthen his scientific legacy. Further interdisciplinary collaborations could also enhance his research portfolio, bringing new perspectives into his work.

Education:

Dr. Tamer Abdelrazik holds an extensive academic background in biological sciences and biotechnology. His early academic training was conducted at recognized institutions in Egypt, followed by advanced studies leading to multiple degrees in the field of microbiology, immunology, and biochemistry. His educational journey enabled him to hone expertise in molecular biology, protein chemistry, tissue culture, and the study of antiviral and anticancer agents. Throughout his academic tenure, Dr. Abdelrazik demonstrated excellence in both theoretical knowledge and experimental practices, often publishing the outcomes of his studies in high-impact journals. He continues to guide future researchers through his supervision of several MSc and Ph.D. students. His education in both the practical and theoretical aspects of biomedical sciences underpins his success as a prominent researcher in various subfields, including therapeutic protein development and environmental biotechnology.

Experience:

Dr. Tamer Abdelrazik’s professional career spans over 15 years, during which he has built a reputation as a leading researcher in the fields of microbiology, biotechnology, and molecular biology. He started his career as a lab specialist at the National Research Centre, Cairo, where he worked from 2006 to 2011. Since 2023, he has held part-time research fellowships at Pharos University and PFIDC, Alexandria, Egypt. In addition to his research duties, he has served as a mentor, advising 9 MSc and 13 Ph.D. students. Dr. Abdelrazik has been the principal investigator on numerous grant-funded projects, focusing on advanced therapies for cancer, COVID-19, and environmental issues. His innovative work, particularly in the development of antimicrobial filters, nanomedicines, and drug delivery systems, has positioned him as a key figure in both academic and industrial research. His career is marked by constant collaboration with national and international research institutions.

Awards and Honors:

Dr. Tamer Abdelrazik has been recognized for his outstanding contributions to scientific research, especially in the fields of biotechnology and medical sciences. He was awarded the prestigious State Encouragement Award in 2019 by the Egyptian Academy of Science and Technology for his advancements in medical technologies. In 2014, he received a certificate from SRTA-City for his significant research achievements and distinguished publications. More recently, Dr. Abdelrazik was ranked in the top 2% of the most impactful scientists globally by Stanford in 2023. These accolades are a testament to his contributions in developing therapeutic agents, including antiviral and anticancer treatments, and his work in environmental health technologies. Dr. Abdelrazik’s recognition by such esteemed institutions highlights his dedication to advancing scientific knowledge and improving human health. These awards solidify his status as a key figure in his field and underscore his influence on global research.

Research Focus:

Dr. Tamer Abdelrazik’s research primarily focuses on advancing medical biotechnology and environmental technologies. He is particularly known for his work in virology, microbiology, and the development of antiviral agents, with a focus on COVID-19. Additionally, his research addresses cancer therapeutics, especially the formulation of nano-complexes to treat various carcinomas. Dr. Abdelrazik’s work includes the investigation and development of novel bioactive compounds such as antimicrobial agents and the fabrication of therapeutic proteins and enzymes. His ongoing projects also explore environmental applications, such as antimicrobial air filters integrated with air-conditioning systems and water purification membranes. His research aims to merge scientific knowledge with practical solutions to address global health challenges. Moreover, he is dedicated to enhancing the delivery of therapeutic agents through innovative drug delivery systems, with a special emphasis on tissue culture, protein chemistry, and immunology.

Publications Top Notes:

  1. Interaction of Jania rubens Polyphenolic Extract as an Antidiabetic Agent with α-Amylase, Lipase, and Trypsin 🧑‍🔬🍀 (2024)
  2. Influence of Cedar Essential Oil on Polyvinyl Alcohol/Cedar Oil/Kaolin Composite Hydrogels 🌲💧 (2023)
  3. Preparation and Physicochemical Characterization of Gelatin–Aldehyde Derivatives 🧪🧬 (2022)
  4. Fatty N-Hexadecanyl Chitosan Derivatives for Biomedical Applications 🧬💉 (2022)
  5. Development of Polyvinyl Alcohol/Kaolin Sponges for Wound Healing Promotion 💉🌱 (2021)
  6. Green Cation Exchange Membrane Doped with Ceramic Nanotubes for Fuel Cells 🔋🔬 (2021)
  7. Effects of Octenyl Succinic Anhydride on Rice Starch Emulsions 🍚💡 (2020)
  8. Antimicrobial Activity of Modified Aminated Chitosan with Aromatic Esters 🦠🍃 (2019)
  9. Cinnamyl O-amine Functionalized Chitosan for Drug Delivery 💊🌿 (2019)
  10. Development of Polyelectrolyte Membranes for Direct Methanol Fuel Cells 🔋🧪 (2019)
  11. Smart Alginate/Chitosan Microcapsules for Colon-Specific Drug Delivery 💊👨‍🔬 (2019)

Conclusion:

Dr. Abdelrazik’s outstanding academic and research contributions make him a highly deserving candidate for the Research for Best Researcher Award. His consistent achievements in high-impact publications, leadership in research projects, and innovative scientific discoveries have placed him at the forefront of his field, solidifying his reputation as an influential researcher.

 

 

 

Yimin Zhu | Immunology Cellular Interactions | Women Researcher Award

Prof. Yimin Zhu | Immunology Cellular Interactions | Women Researcher Award

Prof. Yimin Zhu , Suzhou Institute of Nanotechnology, Chinese Academy of Sciences , China

Prof. Yimin Zhu is a distinguished researcher in bioengineering, specializing in cancer therapies, biomaterials, and peptide screening platforms. With a background in both clinical medicine and biotechnology, she bridges the gap between medical applications and cutting-edge biotechnological innovations. Prof. Zhu completed her master’s in Clinical Medicine from Tianjin Medical University in 1996 and a Ph.D. in Biochemistry from the National University of Singapore in 2005. She has made significant contributions to cancer immunotherapy, drug delivery systems, and biomarker identification. Prof. Zhu’s work has led to over 30 first-author/co-corresponding publications in leading scientific journals, and she holds more than 20 patents. She currently holds a professorship at Suzhou Institute of Nano-Tech and Nano-Bionics, CAS, where her research continues to advance cancer treatments through novel molecular mechanisms and drug delivery platforms.

Publication Profile:

Scopus

Strengths for the Award:

  1. Interdisciplinary Expertise: Prof. Yimin Zhu has a unique blend of clinical medicine and advanced biotechnology expertise, making her well-suited to bridge the gap between medical practice and cutting-edge cancer research. Her background in both the clinical and research fields allows her to tackle cancer therapies from multiple angles.
  2. Impactful Research: Prof. Zhu’s research focuses on critical areas in cancer therapy, such as peptide-based immunotherapy, tumor mechanisms, drug delivery systems, and biomarker discovery. She has published over 30 high-impact papers in leading journals, showcasing her leadership in the field.
  3. Innovative Contributions: She has made substantial contributions to developing peptide-based bispecific CAR T cells and innovative drug delivery systems, with several patents granted. These innovations hold great promise for advancing cancer therapy and improving patient outcomes.
  4. Support and Funding: Prof. Zhu has successfully secured substantial research funding, including multiple grants from the National Natural Science Foundation of China, supporting her groundbreaking research in cancer immunotherapy and biomaterial development.

Areas for Improvement:

  1. Broader Outreach: Although Prof. Zhu has made impressive advancements in cancer research, expanding her work’s visibility to a broader audience in the medical and biotechnology communities, as well as among the general public, could increase the impact of her innovations.
  2. Collaboration and Mentorship: Further expanding interdisciplinary collaborations, particularly with social scientists or clinicians in oncology, could strengthen the practical application of her research and increase its translation into clinical practice. Additionally, mentoring young women in STEM could increase her contribution to fostering diversity in the field.
  3. Public Engagement: Enhancing communication efforts to present her research in a more accessible format for non-experts could be a significant avenue for impact, particularly in terms of attracting additional funding and public interest in her cancer-focused work.

Education:

Prof. Yimin Zhu’s educational journey reflects her interdisciplinary approach to bioengineering and medical science. She earned her Master’s degree in Clinical Medicine from Tianjin Medical University in 1996, where she initially focused on medical practice, gaining hands-on experience as a resident and consultant in Neurology. Her passion for scientific research led her to pursue a Ph.D. in Biochemistry from the National University of Singapore, completed in 2005. This transition to biochemistry allowed her to explore molecular biology, cancer research, and biotechnology. Prof. Zhu’s postdoctoral work at the University of California, Santa Barbara, in Chemical Engineering, further honed her expertise in nanotechnology, bioengineering, and therapeutic innovations. This broad educational foundation, combining clinical experience with cutting-edge research, has uniquely positioned her as a leader in cancer bioengineering and drug delivery systems.

Experience:

Prof. Yimin Zhu’s diverse experience spans both clinical medicine and high-impact research. Between 1996 and 2000, she worked as a resident and consultant doctor in Neurology, which provided a strong foundation in patient care and medical science. Transitioning to research, she served as a research fellow at the National University of Singapore from 2003 to 2005, focusing on biochemistry and cancer-related molecular mechanisms. Prof. Zhu further developed her expertise during her postdoctoral training in the Chemical Engineering Department at the University of California, Santa Barbara, where she explored the intersection of chemical engineering, nanotechnology, and therapeutic interventions. Since joining the Suzhou Institute of Nano-Tech and Nano-Bionics in 2008, she has been a professor, where she leads innovative research in peptide-based cancer therapies, immunotherapy, and drug delivery systems. Her extensive academic background and practical experience have earned her numerous patents and substantial research funding.

Research Focus:

Prof. Yimin Zhu’s research primarily focuses on bioengineering for cancer treatment, peptide screening platforms, and targeted drug delivery systems. Her work involves identifying molecular mechanisms behind tumor cell behavior and developing innovative methods for cancer diagnosis and therapy. She is dedicated to advancing cancer immunotherapy, particularly through the development of peptide-based bispecific CAR T cells targeting key proteins like EGFR and tumor stroma. Prof. Zhu’s research aims to enhance the efficacy of cancer treatments while minimizing side effects. Her studies also explore the development of smart delivery systems, such as extracellular vesicle-based nanodrugs, to improve the precision and effectiveness of drug delivery to tumor sites. Additionally, her work delves into the identification of cancer biomarkers, offering new ways to predict tumor metastasis and optimize treatment regimens. By combining molecular biology, nanotechnology, and biotechnology, Prof. Zhu’s research holds great promise for advancing personalized cancer care.

Publications Top Notes:

  • The peptide-based bispecific CAR T cells target EGFR and tumor stroma for effective cancer therapy 🧬
  • Develop a PD-1-blockade peptide to reinvigorate T-cell activity and inhibit tumor progress 💉
  • Natural killer cells contribute to ‘hot’ tumor regression in the allergic inflammatory environment 🦠
  • Identification of cancer protein biomarker based on cell specific peptide and its potential role in predicting tumor metastasis 🔬
  • Extracellular Vesicle‐Based Nanodrug Delivery 💊
  • Inhibition of Autophagy Promotes the Elimination of Liver Cancer Stem Cells by CD133 Aptamer-Targeted Delivery of Doxorubicin 🧫
  • Dermatophagoides pteronyssinus allergen Der p 22: Cloning, expression, IgE-binding in asthmatic children, and immunogenicity 🌿
  • Reforming the Chimeric Antigen Receptor by Peptide Towards Optimized CAR T Cells With Enhanced Anti-Cancer Potency and Safety 🦠
  • Smart delivery of poly-peptide composite for effective cancer therapy 💡
  • The inhibition of ABCB1/MDR1 or ABCG2/BCRP enables doxorubicin to eliminate liver cancer stem cells ⚙️

Conclusion:

Prof. Yimin Zhu’s research excellence, particularly in cancer therapy, peptide-based immunotherapy, and novel drug delivery systems, positions her as a highly deserving candidate for the Research for Women Researcher Award. Her interdisciplinary approach, groundbreaking innovations, and leadership in publishing high-impact scientific papers make her a trailblazer in the field of bioengineering. By addressing the areas for improvement, particularly in outreach and mentorship, Prof. Zhu could amplify her contributions even further, inspiring the next generation of women scientists and advancing the fight against cancer.

 

 

 

Xi Yao | Cancer Cell Biology | Best Researcher Award

Dr. Xi Yao | Cancer Cell Biology | Best Researcher Award

Dr. Xi Yao , Yunnan University , China

Xi Yao is a prominent researcher in the field of vertebrate evolutionary biology, specializing in dinosaur studies. Currently based at Yunnan University, Kunming, China, he is affiliated with the Center for Vertebrate Evolutionary Biology. With a background in Geology (Bachelor’s from Northwest University, China), Yao further honed his expertise in Vertebrate Paleontology through his Master’s and Ph.D. from the Institute of Vertebrate Paleontology and Paleoanthropology, Chinese Academy of Sciences. He has actively participated in several fossil excavation projects across China, particularly in Xinjiang, Neimongol, and Yunnan, focusing on Jurassic and Cretaceous dinosaur species. His research contributions have garnered recognition in the scientific community with numerous publications in prestigious journals and an active collaboration with international experts.

Publication Profile:

Orcid

Strengths for the Award:

Xi Yao is a highly accomplished paleontologist with a strong background in dinosaur research, specifically focusing on vertebrate evolution and systematics. His educational journey, from a Geology degree to a Master’s and Ph.D. in Vertebrate Paleontology, reflects his deep-rooted expertise in the field. His active role at Yunnan University has allowed him to contribute significantly to understanding the evolution of dinosaur species, particularly in the Jurassic and Cretaceous periods. Notably, his groundbreaking studies on early Jurassic ornithischian dinosaurs and tyrannosauroid locomotion, coupled with his extensive fieldwork across China, position him as a leading expert in dinosaur paleontology. His collaborations with international researchers, such as Prof. John Hutchinson from the Royal Veterinary College and Prof. Corwin Sullivan from the University of Alberta, strengthen his global presence in the scientific community. His publications in well-regarded journals like iScience, Cretaceous Research, and Elife highlight his impactful contributions.

Areas for Improvement:

While Xi Yao has made substantial contributions to dinosaur paleontology, an area for improvement would be expanding his outreach and professional memberships. Engaging more actively with larger paleontological communities and taking editorial roles in academic journals could further boost his visibility and influence. In addition, he has not published books or patents, which are often essential for showcasing a comprehensive body of work in paleontology.

Education:

Xi Yao completed his Bachelor’s degree in Geology from Northwest University, China, laying a foundation in earth sciences. He furthered his academic career at the Institute of Vertebrate Paleontology and Paleoanthropology (IVPP) of the Chinese Academy of Sciences in Beijing, earning both his Master’s and Ph.D. in Vertebrate Paleontology. During his graduate studies, Yao focused on dinosaur evolution and systematics, particularly the study of fossil evidence and ancient ecosystems. His educational journey reflects a blend of geological and paleontological expertise, which supports his comprehensive research on prehistoric life, including the evolutionary trends in dinosaur species. His work at Yunnan University allows him to continue applying his interdisciplinary knowledge to the study of dinosaur fossils, emphasizing both anatomical and ecological perspectives. His academic achievements also include collaborating with other renowned researchers globally, broadening his scientific impact.

Experience:

Xi Yao has accumulated extensive experience in the field of paleontology through both research and fieldwork. After completing his higher education, he became an integral member of the research community at Yunnan University, where he specializes in vertebrate evolutionary biology, particularly dinosaurs. His fieldwork has taken him to several notable excavation sites across China, including Xinjiang, Neimongol, and Yunnan Province, where he has contributed significantly to discovering and analyzing dinosaur fossils. His ongoing research on tyrannosauroid locomotion and dinosaur evolution is supported by grants from prestigious agencies such as the National Natural Science Foundation of China. He has also forged collaborations with leading paleontologists, such as Prof. John Hutchinson from the Royal Veterinary College in the UK, and Prof. Corwin Sullivan from the University of Alberta, Canada. Xi Yao’s extensive hands-on experience in excavations, along with his academic contributions, make him a valuable figure in his field.

Research Focus:

Xi Yao’s primary research interest lies in dinosaur evolution, with a focus on both Jurassic and Cretaceous species. His work has contributed to the understanding of dinosaur phylogeny, anatomy, and locomotion, particularly through his studies on theropods and ornithischians. One of his significant projects involves studying the locomotion of tyrannosauroids through digital modeling, which explores how these iconic predators moved and interacted with their environment. Additionally, he has reported groundbreaking findings on rare early Jurassic ornithischians in Southern China, making important contributions to the understanding of dinosaur diversity during this period. His studies also extend to the description of new dinosaur species, including oviraptorosaurians, therizinosaurians, and ornithomimosaurians, primarily in the Cretaceous of northern China. This focus on dinosaur systematics not only enriches the scientific community’s understanding of dinosaur lineage but also sheds light on broader evolutionary patterns of life on Earth.

Publications Top Notes:

  • “New evidence for the earliest ornithischian dinosaurs from Asia” 📜 (iScience, 2024)
  • “A new ankylosaurid dinosaur from the Upper Cretaceous of Jiangxi Province, southern China” 🦕 (Historical Biology, 2024)
  • “New ornithomimosaurian pelvis from the Upper Cretaceous Erlian Formation of Nei Mongol, North China” 🦖 (Cretaceous Research, 2022)
  • “A new early branching armored dinosaur from the Lower Jurassic of southwestern China” 🛡️ (Elife, 2022)
  • “A new transitional therizinosaurian theropod from the Early Cretaceous Jehol Biota of China” 🦖 (Scientific Reports, 2019)
  • “Caenagnathasia sp. from the Iren Dabasu Formation of Erenhot, Nei Mongol, China” 🦕 (Vertebrata PalAsiatica, 2015)

Conclusion:

Xi Yao is an exceptional candidate for the Best Researcher Award due to his outstanding contributions to the field of dinosaur evolution and systematics. His research has not only expanded our understanding of dinosaur diversity but has also provided new insights into locomotion and dinosaur phylogeny. His dedication to fieldwork and collaboration with international researchers adds value to his research endeavors. Despite some areas for improvement, such as increased professional memberships and diversification of publications, his overall achievements place him among the top researchers in the field. Therefore, Xi Yao deserves strong consideration for this prestigious award.

 

 

 

Yingrong Du | Liver diseases | Best Researcher Award

Prof. Yingrong Du | Liver diseases | Best Researcher Award

Prof. Yingrong Du , The Third People’s Hospital of Kunming , China

Dr. Du Yingrong is a Chief Physician at Dali University’s Sixth Affiliated Hospital (Kunming Third People’s Hospital), specializing in cardiovascular medicine. With over three decades of experience, Dr. Du has made significant contributions to clinical medicine and healthcare management. He is dedicated to advancing patient care, particularly in cardiovascular health, and is actively involved in several research projects, particularly in the areas of atherosclerosis and chronic non-communicable diseases. Dr. Du has also focused on improving healthcare systems in rural China and addressing public health challenges such as COVID-19. His expertise extends to both clinical work and hospital management

Publication Profile:

Scopus

Strengths for the Award:

Dr. Du Yingrong demonstrates exceptional expertise in both clinical medicine and research, making significant contributions in cardiovascular health, atherosclerosis, and public health. He has a strong academic background with advanced education in Hospital Management and Clinical Medicine. As the Chief Physician at Dali University’s Sixth Affiliated Hospital, he has exhibited leadership in managing cardiovascular care, implementing innovative emergency treatment systems, and addressing healthcare disparities in rural China. Dr. Du has led and participated in several research projects funded by the National Natural Science Foundation of China and local government bodies, showcasing his commitment to scientific advancement and public health improvements.

Areas for Improvement:

While Dr. Du has made remarkable strides in research, further enhancing the interdisciplinary collaboration across different health sectors could strengthen his future projects. Expanding his research into broader, international contexts, and diversifying his focus to include emerging areas in global healthcare trends could also provide additional opportunities for groundbreaking research.

Education:

Dr. Du completed his Master’s Degree in Hospital Management from Flinders University and Nankai University (2012-2014). Prior to this, he earned his Bachelor’s Degree in Clinical Medicine from Kunming Medical University (1988-1992). His strong educational foundation has supported his distinguished career in both medical practice and healthcare administration, particularly in managing complex clinical departments and participating in innovative research efforts in cardiovascular health.

Experience:

Dr. Du has extensive experience at Dali University’s Sixth Affiliated Hospital (Kunming Third People’s Hospital), where he has worked since 1992. Starting as a physician in the Cardiovascular Department, he advanced through roles such as Attending Physician, Deputy Chief Physician, and ultimately Chief Physician. His leadership and expertise have significantly contributed to the hospital’s growth, particularly in the cardiovascular field. Dr. Du has been instrumental in several key research projects, such as optimizing emergency treatment systems for COVID-19 and exploring health disparities in minority populations in Yunnan province.

Research Focus:

Dr. Du’s research focus spans cardiovascular diseases, atherosclerosis, public health, and minority health disparities. He has been involved in multiple National Natural Science Foundation and local government-funded projects. His key research interests include studying the effects of triterpenoid compounds on atherosclerosis and exploring clinical treatment methods for chronic diseases in underserved populations. His work aims to improve healthcare delivery, treatment efficacy, and the cultural competence of medical professionals, especially in minority areas of China.

Publications Top Notes:

  1. Ethnic disparities in the prevalence of chronic non-communicable diseases and its multimorbidity among older adults in rural southwest China 📚🌍
  2. Inflammation markers and the risk of hypertension in people living with HIV 🩺🔥
  3. New cycloartane triterpenes from the roots of Cimicifuga foetida 🌿💡
  4. Omega-6 fatty acids down-regulate matrix metalloproteinase expression in a coronary heart disease-induced rat model 🐀💪

Conclusion:

Dr. Du Yingrong is a highly qualified and dedicated researcher who has made significant contributions to clinical medicine and healthcare research. His leadership in addressing cardiovascular health, minority health disparities, and the COVID-19 pandemic exemplifies his ability to combine clinical expertise with impactful research. He is undoubtedly a strong candidate for the “Best Researcher Award,” with his ongoing contributions to healthcare and public health paving the way for significant improvements in both clinical practice and health system management.

 

 

 

Mai Kadry | Molecular chemistry | Best Researcher Award

Assist. Prof. Dr. Mai Kadry | Molecular chemistry | Best Researcher Award

Assist. Prof. Dr. Mai Kadry , National Research Center , Egypt

Mai Osman Mohamed Kadry is a dedicated biochemist, currently working as a researcher in the Therapeutic Chemistry Department at the National Research Centre, Cairo, Egypt. She holds a Doctorate in Biochemistry from Cairo University (2016) and an MSc in Pharmaceutical Sciences from Helwan University (2008). Her primary expertise lies in the field of therapeutic chemistry, with a focus on the biochemical effects of various treatments and their therapeutic potential. In addition to her research, Kadry has academic experience, having taught pharmacognosy at 6 October University. Her work often involves exploring the effects of nanotechnology, antioxidants, and herbal medicines on oxidative stress, toxicity, and cancer treatment. Kadry has contributed significantly to several projects and has published numerous research papers in high-impact journals. She is a well-rounded professional with strong training in various biochemical techniques and computational tools.

Publication Profile:

Scopus

Strengths for the Award:

  1. Academic and Professional Background:
    • Mai Kadry holds a Doctoral degree in Biochemistry, showcasing a high level of academic commitment and specialization. Her focus on cutting-edge research topics such as the amelioration of titanium dioxide-induced oxidative injury, as well as her studies on pharmaceutical and biochemical sciences, highlights her expertise.
    • She has a significant teaching background in the academic field, particularly in the area of pharmacognosy, demonstrating her ability to contribute to the development of future researchers in the field.
  2. Research Output and Publications:
    • Kadry has made substantial contributions to scientific literature, particularly in toxicology and therapeutic chemistry, with numerous research articles published in reputable journals. This includes studies on nano-formulations, the effects of titanium dioxide, and the therapeutic potential of resveratrol.
    • Her involvement in various high-impact research papers underlines her dedication to advancing her field. Additionally, the growing citation of her work further demonstrates the relevance and influence of her research.
  3. Collaboration and Research Initiatives:
    • Kadry has actively participated in multiple innovative research projects at the National Research Centre, focusing on important areas such as nanobiotechnology, hepatocellular carcinoma, and diabetes treatment.
    • Her interdisciplinary approach, involving metabolomics, nanotechnology, and toxicity assessments, shows a broad and comprehensive research capacity, critical for addressing complex health challenges.
  4. Training and Expertise:
    • Kadry has participated in numerous training courses, covering vital techniques like PCR, ELISA, HPLC, and bioinformatics, further strengthening her methodological skills.
    • Her expertise extends to a range of laboratory techniques that are essential for high-quality research in biochemistry and therapeutic chemistry, ensuring the reliability and depth of her scientific investigations.

Areas for Improvement:

  1. Broader Recognition and Networking:
    • While Kadry has published extensively, there could be more emphasis on expanding her research network internationally. Increased participation in global conferences and collaborative research could further elevate her reputation.
  2. Public Outreach and Communication:
    • Enhancing public awareness of her research, possibly through outreach programs or public lectures, could help bridge the gap between scientific research and society. This would make her research more accessible and valuable for a wider audience.
  3. Interdisciplinary Application:
    • While Kadry has shown proficiency in fundamental biochemical research, exploring interdisciplinary applications of her work could bring new insights. For example, connecting her findings to practical medical treatments or developing clinical applications could offer significant real-world value.

Education:

Mai Osman Mohamed Kadry earned her Doctoral degree in Biochemistry from the Faculty of Pharmacy, Cairo University, in 2016, with a dissertation titled “Amelioration Of Nano-sized Titanium Dioxide-Induced Oxidative Injury in Mice by Some Antioxidants.” She holds a Master of Science in Pharmaceutical Sciences from Helwan University (2008), where her research focused on “The Possible Synergistic Role of Phytic and Catechin in Ameliorating the Deteriorative Biochemical Effects Induced By Carbon Tetrachloride in Rats.” Kadry completed her B.Sc. in Pharmaceutical Sciences at Ain Shams University in 2003, graduating with honors and a cumulative grade of Very Good. In addition to her academic qualifications, she has participated in various training courses, including bioinformatics, biosstatistics, scientific typewriting, and protein electrophoresis at the National Research Centre. Her education has provided a robust foundation in pharmaceutical science and biochemistry.

Experience:

Mai Osman Mohamed Kadry has over a decade of academic and research experience in biochemistry and pharmaceutical sciences. She worked as a researcher in the Therapeutic Chemistry Department at the National Research Centre, Cairo, Egypt, where she contributed to multiple research projects related to nanobiotechnology, metabolomics, and the therapeutic efficacy of herbal and chemical entities in treating cancer and diabetes. In her academic career, she taught pharmacognosy at 6 October University (2003-2004) and participated in academic development and quality assurance according to National Commission for Academic Accreditation standards. Kadry’s extensive research experience includes involvement in projects investigating the effects of nanoparticles, herbal medications, and novel chemical compounds on oxidative stress, liver injury, and cancer. She is proficient in a variety of biochemical laboratory techniques, including PCR, ELISA, and HPLC, which have been essential for her research efforts.

Research Focus:

Mai Osman Mohamed Kadry’s research focuses on the biochemical effects of various therapeutic agents, particularly in the areas of nanotechnology, antioxidants, and their role in combating oxidative stress, toxicity, and cancer. Her research aims to explore the potential of nanoparticles, such as titanium dioxide, in ameliorating damage caused by oxidative stress in mice models. She is deeply involved in projects related to the therapeutic properties of herbal medications and chemical entities in treating diseases like liver cancer and diabetes. Kadry is also interested in examining the synergistic effects of natural compounds, such as catechin and phytic acid, in mitigating biochemical damage induced by toxic substances like carbon tetrachloride. Her work further extends to studying autophagy and cell death pathways in response to chemotherapy and other therapeutic agents. Through her research, Kadry seeks to identify novel treatments and biomarkers that can improve the safety and efficacy of therapies for various diseases.

Publications Top Notes:

  1. Titanium nanostructure mitigating doxorubicin–induced testicular toxicity in rats via regulating major autophagy signaling pathways 🧬💉
  2. Inflammatory mediators-induced DNA damage in liver and brain injury: Therapeutic approach of 5-Methoy-N-acetyltryptamine 🧠🩺
  3. Necroptosis and autophagy in cisplatinum-triggered nephrotoxicity: Novel insights regarding their prognostic and diagnostic potential 🩸🔬
  4. Resveratrol-based nano-formulations as an emerging therapeutic strategy for ovarian carcinoma: autophagy stimulation and SIRT-1/Beclin/MMP-9/P53/AKT signaling 💊🌿
  5. miR-122-IGF-1R signaling allied through the dysregulated lncRNA MALAT-1 expression in gastric carcinoma 🍽️🧬
  6. Reciprocal crosslink among MeCP2/BDNF /CREB signaling pinpointed in autism spectrum disorder 🤯🔗
  7. CRISPR-Cas9 genome and long non-coding RNAs as a novel diagnostic index for prostate cancer therapy via liposomal-coated compounds 🧬💉
  8. Collaboration of Hprt/K-RAS/c-Myc mutation in the oncogenesis of T-lymphocytic leukemia: a comparative study 🧬🩺
  9. Thioctic acid shield against lipopolysaccharide depression and endoplasmic reticulum stress: GR7M/Homer/ATF6 signaling 💉🧬
  10. Titanium dioxide nanostructure-loaded Adriamycin surmounts resistance in breast cancer therapy: ABCA/P53/C-myc crosstalk 💪💊

Conclusion:

Mai Osman Mohamed Kadry demonstrates remarkable potential and has made valuable contributions to the fields of biochemistry and therapeutic chemistry. Her academic background, research output, and active involvement in high-impact projects make her a strong contender for the “Best Researcher Award.” While there is room for growth in terms of global outreach and practical applications, her work undoubtedly plays a crucial role in advancing scientific knowledge, particularly in toxicology and the therapeutic use of nanomaterials. Therefore, she is highly deserving of consideration for this prestigious award.