Tamara Braut | Cancer Cell Biology | Innovative Research Award

Prof. Dr. Tamara Braut | Cancer Cell Biology | Innovative Research Award

Prof. Dr. Tamara Braut | Faculty of Medicine, University of Rijeka/ENT Clinic, Clinical hospital centre Rijeka | Croatia

Professor Tamara Braut, MD, is a renowned Croatian otorhinolaryngologist and Full Professor at the Faculty of Medicine, University of Rijeka. She serves as the Head of the Department of Otorhinolaryngology and Head and Neck Surgery. Her clinical expertise and academic leadership have significantly contributed to advancements in the diagnosis and treatment of head and neck cancers, particularly laryngeal carcinoma. With over two decades of experience, Dr. Braut is widely recognized for her work in molecular oncology, HPV-associated head and neck tumors, and translational medicine. A frequent collaborator on interdisciplinary and international projects, she is committed to personalized medicine and innovative approaches in clinical research. Her impressive portfolio of peer-reviewed publications, including case studies, multicenter analyses, and biomarker-based diagnostics, highlights her dedication to evidence-based practice and academic excellence. Professor Braut’s academic leadership and clinical insight place her among the top contributors in her specialty within Croatia and internationally.

Publication Profile:

Google Scholar

Strengths For Award:

  • Pioneering work in head and neck oncology and molecular diagnostics

  • Significant publication record in high-impact journals

  • Collaborative multicenter research and precision medicine orientation

  • Demonstrated leadership in academic and clinical settings

  • Integration of clinical insights with research innovation

Areas for Improvement:

  • Broaden research beyond oncology to explore ENT-related AI/technology

  • Increase international collaborations and visibility at global conferences

  • Expand into clinical trials for therapeutics in HPV+ cancers

🎓 Education: 

Prof. Tamara Braut received her Doctor of Medicine (MD) degree from the University of Rijeka, Croatia, where she also completed her specialization in Otorhinolaryngology. Her academic path was distinguished by an early interest in oncology, molecular pathology, and surgical innovation. She pursued postgraduate training and research with a focus on laryngeal and head and neck cancers. Throughout her education, she was actively involved in academic research, participating in numerous national and international conferences, which sharpened her analytical and investigative skills. She later obtained her PhD with a focus on molecular markers in squamous cell carcinoma. Over the years, she has pursued continuous professional development in precision medicine, oncology biomarkers, and evidence-based surgical practices. Her academic and clinical training has made her a highly competent physician-scientist, well-versed in both patient care and experimental research.

🧑‍🔬 Experience:

Prof. Tamara Braut has over two decades of experience in clinical and academic medicine. She currently serves as the Head of the Department of Otorhinolaryngology and Head and Neck Surgery at the Faculty of Medicine, University of Rijeka. Her career spans clinical work, academic leadership, surgical practice, and scientific research. She has treated complex cases involving laryngeal and head-neck cancers and has led multidisciplinary teams in oncology care. As an educator, she has supervised medical students, residents, and PhD candidates, many of whom now hold academic and clinical positions. Dr. Braut is a prolific researcher, contributing to over 40 peer-reviewed articles, case studies, and reviews. Her leadership in multicenter studies and her role as a principal investigator in several clinical research projects highlight her competence in collaborative and innovative medical research.

🔬 Research Focus:

Prof. Braut’s research focus lies at the intersection of head and neck oncology, molecular diagnostics, and personalized medicine. She has a keen interest in biomarker discovery, especially in HPV-positive head and neck squamous cell carcinomas, and the role of EGFR signaling pathways in cancer progression. Her work includes translational research linking clinical findings with molecular data to improve prognosis, diagnosis, and treatment strategies. She has also explored the impact of hormonal therapies, gene expression markers like Ki-67 and IMP3, and novel imaging and diagnostic tools. In recent years, she has expanded her interest to gastroesophageal reflux disease and its implications in ENT disorders. Her contributions reflect a consistent commitment to advancing precision medicine, long-term patient follow-up, and multimodal treatment outcomes. She continues to integrate research into clinical practice, thereby fostering innovation and improved patient care in the otorhinolaryngology field.

📚 Publications List Top Notes:

  1. 🧬 Laryngeal SCC shows stronger Nectin-4 vs Nectin-2 expression – CIMB (2025)

  2. 🥗 GERD Management: From PPIs to Diet & Lifestyle – Gastrointest. Disord. (2025)

  3. 🔍 Advances in HPV-Positive Head & Neck Cancer Diagnostics – Biomolecules (2024)

  4. 🧪 Biomarkers in HPV+ Head and Neck SCC: Precision Medicine – Diagnostics (2024)

  5. 💉 Testosterone Therapy in Advanced Head & Neck SCC – Crit. Rev. Oncol. Hematol. (2023)

  6. 🏥 Long-Term Care in Laryngeal Cancer: Multicenter Analysis – J Pers. Med (2023)

  7. 📊 5-Year Clinical Course in Laryngeal Tumors – Acta Clin. Croatica (2022)

  8. 🧫 Renal Cell Carcinoma Metastasis to Larynx: Rare Case – Medicina Flum (2021)

  9. 🧠 Posttraumatic Vernet Syndrome without Fracture: Case Study – Medicine (2021)

  10. ⚛️ Nuclear EGFR Expression = Poor Survival in Laryngeal Ca – AIMM (2021)

Conclusion:

Prof. Tamara Braut is highly deserving of the Innovative Research Award. Her work showcases originality, clinical relevance, and scientific depth. With a robust academic and clinical foundation, she continues to push the boundaries in ENT oncology and diagnostics.

 

baofeng wang | Cancer Cell Biology | Best Researcher Award

Prof. baofeng wang | Cancer Cell Biology | Best Researcher Award

Prof. baofeng wang, Department of Radiation Therapy, Second Affiliated Hospital of Medical School, Xi’an Jiaotong University, Xi’an 710004, China, China

Dr. Baofeng Wang is a Professor and Associate Chief Physician at The Second Affiliated Hospital of Xi’an Jiaotong University. He serves as Head of the Abdominal Oncology Group in the Department of Radiation Oncology and is a Master’s Supervisor. Renowned for his expertise in abdominal and liver cancers, Dr. Wang actively contributes to several professional organizations, including the Chinese Society for Radiation Oncology (CSRO). As a reviewer for top journals and a recipient of multiple prestigious research awards, his work integrates clinical excellence with cutting-edge research. He has led three national and provincial-level projects and has authored over 40 scientific articles, with more than 10 published in SCI-indexed journals. His recent work focuses on ferroptosis, immune regulation in cancer, and BNCT treatment planning, marking him as a leading figure in translational oncology research.

Publication Profile: 

Scopus

✅ Strengths for the Award:

  1. Academic and Clinical Leadership:

    • Professor, Associate Chief Physician, and Master’s Supervisor.

    • Head of the Abdominal Oncology Group at a leading national medical institution.

    • Actively leads and shapes treatment protocols in radiation oncology.

  2. Research Productivity and Impact:

    • Authored over 40 scientific publications, with more than 10 indexed in SCI journals.

    • Principal Investigator for 3 major funded research projects.

    • Co-investigator in 5 additional national and provincial projects.

    • Reviewer for high-impact international journals, ensuring scientific rigor in oncology research.

  3. Recognition and Awards:

    • Winner of two First Prizes for Scientific and Technological Progress in Higher Education Institutions.

    • Received a Second Prize from the Shaanxi Provincial Scientific and Technological Progress Awards.

  4. Professional Influence:

    • Holds multiple key positions in national and provincial medical societies, especially within the Chinese Society for Radiation Oncology (CSRO).

    • Active in bridging research, clinical practice, and public health education.

  5. Recent Research Focus:

    • Investigating mechanisms of radioresistance via ferroptosis and cholesterol metabolism.

    • Advancing boron neutron capture therapy (BNCT) planning and immunoregulatory pathways in breast cancer and hepatocellular carcinoma.

⚙️ Areas for Improvement:

  1. Global Collaboration:

    • While domestically influential, expanding international collaborations and partnerships could further elevate the research impact and visibility.

  2. Citation Index and Research Translation:

    • Despite a good number of publications, a higher citation count and more translational outcomes into clinical practice would strengthen the award candidacy further.

  3. Innovation Leadership:

    • Developing patents or pioneering novel therapeutic technologies would add to innovation metrics.

🎓 Education:

Dr. Baofeng Wang received rigorous academic training in the medical sciences, specializing in oncology and radiation therapy. After completing his undergraduate medical degree, he pursued postgraduate studies focused on radiation oncology and tumor biology. His advanced academic pursuits led to a comprehensive understanding of radiobiology, imaging-guided radiotherapy, and molecular oncology. He continuously updates his knowledge through professional development programs and has contributed to both educational and research domains by mentoring postgraduate students. His commitment to academic excellence is evident through his role as a Master’s Supervisor, guiding the next generation of clinical researchers. Dr. Wang’s educational background has equipped him with the skills necessary to integrate evidence-based medicine with innovative research, particularly in the fields of liver cancer and immuno-oncology.

🧪 Professional Experience:

With over 15 years of clinical and academic experience, Dr. Baofeng Wang is a leading figure in the field of radiation oncology. Currently a Professor and Associate Chief Physician, he heads the Abdominal Oncology Group at The Second Affiliated Hospital of Xi’an Jiaotong University. He has been instrumental in developing individualized radiotherapy protocols for complex tumors. His leadership roles in various national and provincial oncology organizations highlight his influence in shaping cancer treatment strategies. He has served as Principal Investigator for several research grants from the National Natural Science Foundation of China and provincial R&D bodies. Additionally, Dr. Wang plays an active role in academic peer review and science promotion in Shaanxi province. His blend of clinical acumen and research proficiency makes him a cornerstone in the advancement of radiotherapy techniques and translational oncology.

🔬 Research Focus:

Dr. Wang’s research focuses on the intersection of radiation oncology, tumor metabolism, and immunoregulation. He investigates how cellular mechanisms such as ferroptosis and cytokine modulation contribute to radioresistance and tumor progression. A major area of interest is the optimization of boron neutron capture therapy (BNCT) treatment planning, aiming to enhance therapeutic outcomes in abdominal cancers. His work also explores the role of tumor-infiltrating immune cells and how factors like interleukin-10 influence immune suppression and therapy response. By integrating molecular diagnostics with imaging-guided radiotherapy, Dr. Wang seeks to improve precision medicine strategies. His translational research aims to convert lab-based discoveries into clinically viable cancer treatments, particularly for liver, breast, and gastrointestinal cancers. Through collaborative and interdisciplinary research, Dr. Wang’s work continues to push boundaries in oncology innovation.

📚 Publications Top Notes:

  1. 🧬 Recent research progress of BNCT treatment planning system

  2. 🔗 SCARB1 links cholesterol metabolism-mediated ferroptosis inhibition to radioresistance in tumor cells

  3. 🎯 BAFF overexpression in triple-negative breast cancer promotes tumor growth by inducing IL-10-secreting regulatory B cells that suppress anti-tumor T cell responses

  4. 🛡️ Interleukin-10 overexpression in 4T1 cells: A gateway to suppressing mammary carcinoma growth

📌 Conclusion:

Dr. Baofeng Wang exemplifies the qualities of an exceptional clinical researcher, balancing leadership, clinical service, and impactful research. His contributions to radiation oncology—particularly in abdominal and liver cancers—along with national-level recognition and funding, make him a highly suitable and competitive candidate for the Best Researcher Award. Continued expansion of his international footprint and translational outputs would position him even more prominently on the global stage.

Raul Valenzuela | Cancer Cell Biology | Best Researcher Award

Assist. Prof. Dr. Raul Valenzuela | Cancer Cell Biology | Best Researcher Award

Assist. Prof. Dr. Raul Valenzuela , MD Anderson Cancer Center , United States

Dr. Raul F. Valenzuela Perez is a highly accomplished Assistant Professor of Musculoskeletal Imaging at The University of Texas MD Anderson Cancer Center. With over two decades of medical experience, he combines expertise in radiology, oncology, and advanced imaging techniques. Originating from Chile, Dr. Valenzuela earned his MD from Universidad de Chile and pursued advanced training in health administration and imaging sciences. His global perspective and collaborative research efforts have made him a prominent figure in musculoskeletal tumor imaging. He is board-certified in radiology in both the U.S. and Chile and is actively licensed in Texas and Florida. Dr. Valenzuela’s dedication to oncologic imaging, radiomics, and MRI innovations has resulted in numerous peer-reviewed publications, especially in the field of sarcoma imaging. Through ongoing work in developing and validating novel imaging biomarkers, he continues to shape the future of cancer diagnostics and personalized treatment approaches.

Publication Profile: 

Scopus

✅ Strengths for the Award:

  1. Prolific Research Output 📚
    Dr. Valenzuela has published extensively in high-impact journals like Scientific Reports, JCO Clinical Cancer Informatics, and Journal of Radiology & Oncology, with recent work in 2023–2025 focusing on radiomics, MRI biomarkers, and musculoskeletal oncology.

  2. Innovation in Imaging Techniques 💡
    He has pioneered the use of contrast-enhanced susceptibility-weighted imaging (CE-SWI) and quantitative diffusion-weighted MRI to evaluate soft tissue sarcomas and treatment response — advancing imaging beyond traditional RECIST criteria.

  3. Collaborative Multidisciplinary Work 🤝
    Dr. Valenzuela consistently co-authors with surgical oncologists, pathologists, and radiologists, highlighting his collaborative research approach that bridges disciplines.

  4. International Clinical Credibility 🌎
    He is licensed in the U.S. (Texas & Florida) and Chile, and board-certified in both American and Chilean radiology boards, reflecting his global expertise and trust in varied medical systems.

  5. Academic Leadership at MD Anderson 🎓
    As an Assistant Professor at one of the world’s top cancer centers, he contributes to education, clinical care, and high-level cancer imaging research.

⚙️ Areas for Improvement:

  1. Recognition and Awards Disclosure 🏅
    While the publication record is impressive, public listing of prior individual awards, fellowships, or grants would strengthen his profile further for award consideration.

  2. Principal Investigator Roles 🧪
    Although highly involved in collaborative projects, leading major multi-center trials or imaging consortia as principal investigator would elevate his leadership status.

  3. Expanded Public Science Communication 🗣️
    Increasing outreach via conferences, keynote talks, or educational platforms (like webinars or radiology workshops) could enhance his visibility in the broader scientific community.

🎓 Education:

Dr. Raul F. Valenzuela Perez holds an MD from Universidad de Chile (1993), where he laid the foundation for his distinguished medical and academic career. Alongside his medical training, he pursued further specialization in healthcare management, earning two certificates from the University of Chile Business School: one in Business and Health Administration (2003) and another in Process Management and Health Administration (2005). This unique blend of medical and administrative education empowers Dr. Valenzuela with a strategic understanding of healthcare systems and leadership. His academic journey highlights a commitment to continuous learning and cross-disciplinary excellence. As a thought leader in radiologic sciences, Dr. Valenzuela has integrated his business knowledge with clinical expertise to enhance imaging workflows and patient-centered care, especially in high-impact cancer institutions like MD Anderson. His education reflects both clinical proficiency and managerial insight, laying the groundwork for his contributions to musculoskeletal oncology imaging.

🏥 Experience:

Since September 2019, Dr. Valenzuela has served as an Assistant Professor in Musculoskeletal Imaging at The University of Texas MD Anderson Cancer Center, one of the world’s leading cancer research institutions. Prior to his tenure in the U.S., he developed a robust clinical background in Chile, where he practiced and taught radiology. With licenses from the Texas Medical Board, Florida Medical Board, and Chilean Medical Association, his clinical credentials span internationally. He is also certified by the American Board of Radiology and the Chilean Radiology Board. At MD Anderson, Dr. Valenzuela plays a key role in advancing diagnostic imaging for musculoskeletal tumors, particularly soft tissue sarcomas. His responsibilities include patient care, teaching, research, and contributing to the development of advanced imaging protocols. Known for his collaborative style and interdisciplinary approach, he is a respected mentor and a valued contributor in the field of cancer imaging.

🏅 Awards and Honors:

While specific named awards are not detailed in the provided data, Dr. Raul F. Valenzuela Perez’s growing publication record, leading research in radiomics, and collaborative work at MD Anderson suggest a strong reputation in his field. His continuous publication in high-impact journals, such as Scientific Reports, JCO Clinical Cancer Informatics, and Journal of Radiology & Oncology, indicate recognition by peers and ongoing contributions to advancing cancer imaging. His role in multidisciplinary research teams and innovative use of advanced MRI techniques position him as a strong candidate for awards like Best Researcher. His efforts in improving imaging criteria beyond RECIST and validating AI-based radiomic frameworks show both vision and leadership. Though a detailed list of awards isn’t cited, his contributions to musculoskeletal oncology, particularly in sarcoma treatment response evaluation, reflect a track record of academic excellence and clinical impact, meriting honor and distinction in his specialty.

🔬 Research Focus:

Dr. Valenzuela’s primary research focus lies in advanced imaging for musculoskeletal oncology, particularly the integration of radiomics, perfusion-weighted MRI, and contrast-enhanced susceptibility-weighted imaging (CE-SWI) for tumor characterization and treatment monitoring. His work is centered on improving diagnosis and predicting response in soft-tissue sarcomas, such as undifferentiated pleomorphic sarcoma (UPS) and desmoid fibromatosis. He actively collaborates on multi-institutional studies, applying quantitative imaging biomarkers and AI-driven radiomic models to identify tumor behavior patterns and personalize therapy. A key aspect of his research is the evaluation of multiparametric MRI features, including diffusion-weighted and dynamic contrast-enhanced imaging. His publications reveal a commitment to pushing boundaries in functional imaging and improving imaging response criteria beyond traditional RECIST methods. Through his research, Dr. Valenzuela aims to contribute to precision medicine in oncology, bridging radiology and data science to enhance patient outcomes and streamline therapeutic decision-making.

📚 Publications Top Notes:

  1. 🧠 Perfusion-weighted imaging features predicting UPS treatment responseSci Rep, 2024

  2. 🧬 Radiomics by diffusion-weighted MRI for extremity UPS predictionJ Radiol Oncol, 2024

  3. 🧲 Contrast-enhanced SWI for musculoskeletal oncologic pathologyJ Radiol Oncol, 2024

  4. 💉 Perfusion imaging of the musculoskeletal systemMagn Reson Imaging Clin N Am, 2024

  5. 🤖 Cancer radiomic and perfusion imaging automated frameworkJCO Clin Cancer Inform, 2024

  6. 🧠 Idiopathic intracranial hypertension: MRI vs venous sinus pressureRev Chil Radiol, 2023

  7. 📊 CE-SWI in desmoid fibromatosis response assessmentTumor Discov, 2023

  8. 📈 Multiparametric MRI for treatment and recurrence in sarcomaJ Radiol Oncol, 2023

  9. 🔍 ADC map-based radiomics for sacral tumor differentiationJCO Precis Oncol, 2023

  10. 📐 Advanced imaging in musculoskeletal oncology (ABASTI Part I)Semin Ultrasound CT MR, 2021

  11. 🧪 Radiomic features of CE-SWI in UPS treatment responseJCO Clin Cancer Inform, 2025

📝 Conclusion:

Dr. Raul F. Valenzuela Perez is a highly deserving candidate for the Best Researcher Award. His innovative contributions to musculoskeletal oncologic imaging, especially in applying radiomic models and advanced MRI techniques, place him at the forefront of translational cancer imaging. His interdisciplinary collaborations and growing body of work have strong clinical impact, particularly for sarcoma management.

With additional visibility through PI roles and recognition through formal honors, Dr. Valenzuela’s already impressive profile is on a trajectory toward international distinction. Based on the current accomplishments and ongoing impactful research, he is highly recommended for this award.

Huifeng Hao | Tumor pharmacology | Best Researcher Award

Dr. Huifeng Hao | Tumor pharmacology | Best Researcher Award

Dr. Huifeng Hao , Peking University Cancer Hospital , China

Dr. Huifeng Hao is an Assistant Investigator at Peking University Cancer Hospital, specializing in the integration of Chinese and Western medicine. He holds a Ph.D. from Peking University Health Science Center, where he explored Chinese-Western medical integration. His research journey began with a Bachelor’s in Clinical Medicine from Hebei Medical University. Dr. Hao has accumulated valuable postdoctoral experience at Peking Union Medical College (PUMC) in Vascular Pharmacology. His work has greatly contributed to the understanding of cancer progression, focusing on the interactions between cancer cells and vascular endothelial cells and the therapeutic effects of Traditional Chinese Medicine. With over a decade of expertise, Dr. Hao has published extensively in renowned journals, addressing critical topics in cancer research, endothelial cell function, and vascular health.

Publication Profile:

Orcid

Strengths for the Award:

  1. Extensive Educational and Research Background: Dr. Huifeng Hao has a comprehensive and solid academic foundation. With a Bachelor’s degree in Clinical Medicine from Hebei Medical University and a Ph.D. in the Integration of Chinese and Western Medicine from Peking University Health Science Center, his educational background is robust. Moreover, his postdoctoral research in Vascular Pharmacology at Peking Union Medical College significantly bolsters his expertise, particularly in vascular biology and its implications in cancer progression.

  2. Groundbreaking Research Areas: Dr. Hao’s research primarily focuses on the complex interactions between cancer cells and vascular endothelial cells, along with exploring how Traditional Chinese Medicine (TCM) can influence cancer progression. This intersection of modern pharmacology and traditional medicine offers a unique and innovative approach to cancer therapy. His studies on cancer metastasis, endothelial cell signaling, and the use of TCM as a potential therapeutic strategy for cancer represent cutting-edge work.

  3. Impressive Publication Record: Dr. Hao has co-authored numerous high-impact publications in leading journals, such as Phytomedicine, Frontiers in Pharmacology, Journal of Ethnopharmacology, and Journal of Cellular and Molecular Medicine. His work spans across critical cancer pathways, pharmacological interventions, and the exploration of novel therapeutic agents like Marsdenia Tenacissima and Berberine in combating metastasis and endothelial dysfunction.

    • His 2022 papers on the modified Bu-Fei decoction’s effects on lung metastasis and the role of CUEDC2 in promoting breast cancer progression are particularly notable for their novel findings and potential clinical applications.
  4. Collaborative and Multi-Disciplinary Research: Dr. Hao’s ability to collaborate with a wide array of experts and researchers in diverse fields demonstrates his interdisciplinary approach to solving complex scientific questions. This collaboration enhances the relevance and applicability of his work in various research areas, particularly in cancer biology, pharmacology, and integrative medicine.

  5. Pioneering Work on TCM in Cancer Therapy: Dr. Hao’s research on the role of Traditional Chinese Medicine (TCM) in cancer therapy is especially noteworthy. His studies examining how TCM influences tumor microenvironments and endothelial cell interactions provide critical insights into how integrative medicine might be leveraged to treat cancer in combination with conventional therapies. This pioneering research has the potential to redefine cancer treatments and offer patients holistic therapeutic options.

  6. Strong Impact on Cancer Research: His work on vascular pharmacology, tumor angiogenesis, and metastasis in lung cancer, particularly through the modulation of transforming growth factor beta receptors and nitric oxide signaling, has significant implications for the development of new cancer therapies. His publications are contributing valuable knowledge toward better understanding cancer progression and discovering more effective treatments.

Areas for Improvement:

  1. Broader Research Scope in Clinical Settings: While Dr. Hao’s research has focused heavily on preclinical studies, including animal models and cellular assays, expanding his research into clinical trials or human-based studies would provide essential validation for his findings. Involving clinical datasets and patient-centered research could strengthen the real-world applicability of his work.

  2. Increase in Independent Research Funding: While Dr. Hao has contributed significantly to various collaborative projects, securing independent research grants would allow him more freedom to explore his unique research hypotheses in greater depth and broaden the scope of his investigations.

  3. Expansion of International Collaborations: While Dr. Hao’s collaborations are impressive, further expanding his international network could provide additional insights and allow him to take his research to the global forefront. Partnerships with leading international cancer research institutions could also amplify the impact of his work.

Education:

  • 2004.09-2009.06: Hebei Medical University (Bachelor Degree in Clinical Medicine)
  • 2009.09-2014.06: Peking University Health Science Center (Ph.D. in Integration of Chinese and Western Medicine)
  • 2014.09-2018.08: Peking Union Medical College (Postdoctoral Training in Vascular Pharmacology)

Dr. Hao’s academic journey spans over a decade of rigorous training, blending Western scientific research with Traditional Chinese Medicine. He received his bachelor’s degree in clinical medicine and later pursued his Ph.D. in an interdisciplinary program that focused on integrating these two approaches to medicine. His postdoctoral research in vascular pharmacology furthered his expertise in understanding the physiological and molecular mechanisms of cancer-related vascular changes.

Experience:

  • 2014.09-2018.08: Postdoctoral Researcher, Peking Union Medical College, Vascular Pharmacology
  • 2018.08-Present: Assistant Investigator, Peking University Cancer Hospital, Integration of Chinese and Western Medicine

Dr. Hao’s research career spans significant academic institutions in China. During his postdoctoral research at PUMC, he specialized in vascular pharmacology, focusing on the molecular pathways involved in tumor vasculature. At Peking University Cancer Hospital, Dr. Hao continues to investigate how traditional medicine can alter the interactions between cancer cells and endothelial cells, with a goal of developing novel therapeutic strategies for cancer treatment. His interdisciplinary approach has led to multiple breakthrough discoveries in cancer biology and integrative medicine.

Research Focus:

Dr. Hao’s primary research areas include:

  • Investigating the interactions between cancer cells and vascular endothelial cells, and how these affect cancer progression
  • Exploring the role of Traditional Chinese Medicine (TCM) in regulating cancer cell interactions within the tumor microenvironment, especially with endothelial cells

By bridging the gap between modern biomedical science and traditional medicine, Dr. Hao aims to develop therapies that utilize both modalities to inhibit tumor growth and metastasis. His work focuses on understanding how TCM can modulate endothelial cells and vascular pathways, potentially leading to new treatments for cancer that are more holistic and effective.

Publications Top Notes:

  1. Modified Bu-Fei decoction inhibits lung metastasis via suppressing angiopoietin-like 4 🫁🦠
  2. CUEDC2 Drives β-Catenin Nuclear Translocation and Promotes Triple-Negative Breast Cancer Tumorigenesis 🧬💥
  3. Berberine Suppresses Lung Metastasis of Cancer via Inhibiting Endothelial Transforming Growth Factor Beta Receptor 1 🌱🏥
  4. Marsdenia tenacissima extract disturbs the interaction between tumor-associated macrophages and non-small cell lung cancer cells by targeting HDGF 🌿🧫
  5. The cyclic adenosine monophosphate elevating medicine, forskolin, reduces neointimal formation and atherogenesis in mice 🐭💉
  6. Nitric oxide, a communicator between tumor cells and endothelial cells, mediates the anti-tumor effects of Marsdenia Tenacissima Extract (MTE) 💡🔬
  7. Marsdenia tenacissima extract promotes gefitinib accumulation in tumor tissues of lung cancer xenograft mice via inhibiting ABCG2 activity 💊🔬
  8. Marsdenia tenacissima extract dilated small mesenteric arteries via stimulating endothelial nitric oxide synthase and inhibiting calcium influx 🧪🩸
  9. Protective Role of mPGES-1 (Microsomal Prostaglandin E Synthase-1)-Derived PGE(2) (Prostaglandin E-2) and the Endothelial EP4 (Prostaglandin E Receptor) in Vascular Responses to Injury 💥🩺
  10. Loss of Endothelial CXCR7 Impairs Vascular Homeostasis, and Cardiac Remodeling After Myocardial Infarction ❤️🫀

Conclusion:

Dr. Huifeng Hao’s contributions to cancer research, particularly the intersection of TCM and Western medicine, make him an excellent candidate for the Best Researcher Award. His innovative studies, combined with his dedication to advancing cancer treatment, position him as a leading researcher in his field. His continued research promises to significantly impact both scientific understanding and clinical practices in cancer therapy.