Eunhee Lee | Neuronal Cell Biology | Best Research Article Award

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Dr. Eunhee Lee | Neuronal Cell Biology | Best Research Article Award

Dr. Eunhee Lee, Daegu Gyeongbuk Medical Innovation Foundation, K-MEDI hub, South Korea

Dr. Eun-Hee Lee, Ph.D., is a distinguished biomedical researcher with expertise in therapeutic ultrasound and neurobiology. Currently serving as Senior Researcher and Head of the Advanced Technology Department at the Medical Device Development Center, DGMIF, South Korea, she has consistently contributed to the advancement of focused ultrasound applications in neurological disorders. With over a decade of research experience spanning government institutions and clinical collaborations, Dr. Lee has published extensively in peer-reviewed journals on brain delivery mechanisms, neuroinflammation, and neurodegeneration. Her pioneering studies have deepened our understanding of the blood-brain barrier and the therapeutic potential of ultrasound. Her work stands at the forefront of translational neuroscience, aiming to enhance drug delivery and brain repair mechanisms. Dr. Lee’s dedication to impactful and clinically relevant research makes her a strong contender for the Best Research Article Award.

Publication Profile: 

Scopus

✅ Strengths for the Award

  1. Innovative Research Focus:
    Dr. Lee’s work on focused ultrasound (FUS)-mediated blood-brain barrier (BBB) disruption is at the cutting edge of neurotherapeutics and non-invasive brain drug delivery. Her investigations hold promise for treating neurodegenerative disorders like Alzheimer’s disease and traumatic brain injuries.

  2. Extensive Peer-Reviewed Publications:
    With over 15 high-quality, peer-reviewed articles published from 2019 to 2024 in reputable journals like Scientific Reports, Frontiers in Neuroscience, and Biomedicines, her research output reflects consistent and impactful contributions.

  3. Interdisciplinary Approach:
    Her integration of biomedical engineering, imaging, and neurobiology enhances the translational value of her findings. Numerical modeling and simulation studies further strengthen the clinical feasibility of her techniques.

  4. Clinical and Preclinical Impact:
    Dr. Lee’s work bridges preclinical models (rats, skull simulations) with potential human applications, offering real translational pathways for drug delivery across the BBB.

  5. Leadership and Collaboration:
    As the Head of the Advanced Technology Department at DGMIF, she demonstrates leadership in medical innovation and fosters collaboration between academia, hospitals, and research institutes.

⚠️ Areas for Improvement

  1. Greater International Collaboration:
    While her work is deeply embedded in Korean institutions, expanding partnerships internationally could amplify her research reach and global influence.

  2. Clinical Trial Transition:
    Much of her published work is preclinical. Advancing to clinical trials or human pilot studies would significantly increase the translational impact of her findings.

  3. Public Engagement and Visibility:
    Enhanced visibility through global neuroscience or biomedical engineering conferences could further validate and showcase her research excellence.

🎓 Education:

Dr. Eun-Hee Lee received all her academic training from Chonnam National University, Kwangju, South Korea. She earned her Ph.D. (2007–2010) and M.S. (2005–2007) in Biological Sciences and Technology, gaining extensive knowledge in cellular and molecular biology. Her B.S. in Genetic Engineering (2001–2005) laid the groundwork for her interest in biomedical innovations and neurogenetics. During her graduate and doctoral studies, she focused on cellular pathways and gene expression relevant to neurodegenerative diseases and molecular interventions. Her academic journey shaped her multidisciplinary perspective, merging genetics, bioengineering, and neurobiology. These foundations have enabled her to pursue cutting-edge research on the blood-brain barrier, drug delivery systems, and brain stimulation. Dr. Lee’s strong academic background provides her with the theoretical and technical expertise essential for high-impact research.

🧪 Experience:

Dr. Eun-Hee Lee has more than 14 years of progressive research experience. Since 2017, she has led the Advanced Technology Department at DGMIF, where she develops novel medical devices using therapeutic ultrasound. Prior to this, she worked as a Research Scientist at the Korea Atomic Energy Institute’s Advanced Radiation Technology Institute (2015–2017), where she explored radiation-mediated biological responses. Between 2013 and 2015, she contributed to TB and molecular microbiology research at the Korean Institute of Tuberculosis. Her postdoctoral fellowship (2011–2012) at the NIH’s Division of HIV/AIDS and Tumor Viruses expanded her expertise into virology and immunopathology. Dr. Lee’s multidisciplinary roles across leading institutions demonstrate her adaptability, leadership, and commitment to translational science. Her professional trajectory shows strong contributions to national research priorities in healthcare and medical technology.

🔬 Research Focus:

Dr. Eun-Hee Lee’s research centers on focused ultrasound (FUS) as a non-invasive modality for drug delivery and neural repair. Her work explores ultrasound-mediated blood-brain barrier (BBB) disruption to enhance targeted therapeutic access to the brain. She also investigates ultrasound stimulation’s effects on neurogenesis, neuroinflammation, and neuroprotection in various neurological models including Alzheimer’s disease and spinal cord injury. Another significant area of focus includes numerical modeling of skull structures to improve the precision of transcranial FUS applications. Through collaborations with clinicians and physicists, Dr. Lee has produced evidence-based methodologies for safer, more effective BBB modulation. Her integrative approach, combining bioengineering, neuroimmunology, and computational simulation, is impactful in the field of therapeutic neuromodulation and has implications for treating neurodegenerative and cerebrovascular disorders.

📚 Publications Top Notes: 

  • 🧠 Numerical Investigation of Layered Homogeneous Skull Model for Simulations of Transcranial Focused Ultrasound (2024)

  • 🔥 The New Insight into the Inflammatory Response Following Focused Ultrasound-Mediated Blood-Brain Barrier Disruption (2022)

  • 🧪 Methylene Blue Delivery via Focused Ultrasound Reduces Neural Damage and Amyloid-Beta by AQP-4 Upregulation (2022)

  • 🐀 Novel Animal Model of Spontaneous Cerebral Petechial Hemorrhage Using Focused Ultrasound in Rats (2022)

  • ♻️ Ultrasound Stimulation Improves Inflammation Resolution and Functional Recovery After Spinal Cord Injury (2022)

  • 🚑 Relationship Between Treatment Types and BBB Disruption in Acute Ischemic Stroke: Two Case Reports (2022)

  • 🧲 Effects of Transducer Displacement on Focused Ultrasound in the Rat Brain (2022)

  • 📉 BBB Disruption After Syncope: A DCE-MRI Case Report (2021)

  • 🧪 Verification of BBB Disruption Using Rat Model with Human Skull (2021)

  • 💧 Localized Water Molecule Transport Modulation Post-FUS BBB Disruption (2021)

  • 🚨 DCE-MRI for Evaluating BBB Disruption in Traumatic Brain Injury: Review (2021)

  • 🧬 TREM2 Promotes Natural Killer Cell Development in pNK Cells (2021)

  • 🌿 Gintonin Enhances Donepezil Brain Delivery via LPA and VEGF Receptors (2021)

  • 🔄 Cyclophilin A is a Ligand for TREM2 in Myeloid Cells (2021)

  • 🧠 Local Differences in BBB Permeability Induced by Focused Ultrasound (2020)

  • 💉 Advanced FUS Protocol Improves Doxorubicin Delivery in Rat Brain (2019)

  • 🔄 FUS-Induced Diminished P-glycoprotein via JNK Pathway in Cerebral Vessels (2019)

🧾 Conclusion:

Dr. Eun-Hee Lee is a highly suitable candidate for the Best Research Article Award. Her work is scientifically rigorous, clinically relevant, and methodologically innovative. The focus on ultrasound-mediated drug delivery through the BBB is a transformative area in neuroscience and drug delivery technology. Her comprehensive research output, leadership, and translational potential strongly position her among top contenders for recognition. Encouraging clinical application and broader dissemination will only enhance the already substantial value of her contributions.

Noura Hussein Abdel Hamid | Cell Structure Analysis | Best Researcher Award

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Assist. Prof. Dr. Noura Hussein Abdel Hamid | Cell Structure Analysis | Best Researcher Award

Assist. Prof. Dr. Noura Hussein Abdel Hamid , Zagazig University , Egypt

Dr. Noura Hussein Abedel Hamid Mekawy is a dedicated Egyptian medical academic with extensive expertise in Histology and Cell Biology. Born on April 18, 1981, she graduated with an M.B.B.Ch. from Zagazig University in 2006, followed by a Master’s (2012) and an M.D. (2017) in Histology and Cell Biology from the same institution. Currently, she serves as a Lecturer at Zagazig University’s Faculty of Medicine. Her academic journey is complemented by her passion for medical education, microscopy, and molecular research. Dr. Mekawy has contributed to the field with multiple publications in reputable scientific journals, focusing on histopathological and immunohistochemical studies. She is a member of the Egyptian Society of Histology and Cytology and has completed professional training in self-evaluation and quality assurance in higher education. Her commitment to scientific advancement and education has established her as a respected figure in medical academia.

Publication Profile:

Orcid

✅ Strengths for the Award:

  1. Extensive Research Background
    Dr. Mekawy has authored and co-authored 10 peer-reviewed publications, focusing on histopathology, immunohistochemistry, toxicology, and therapeutic interventions in experimental models.

  2. Specialization in a Vital Medical Field
    Her focus on Histology and Cell Biology is crucial for understanding disease mechanisms and developing new treatment strategies.

  3. Academic Progression & Teaching Role
    She has shown consistent career advancement from Demonstrator to Lecturer, demonstrating leadership and commitment in academia.

  4. Diverse Research Themes
    Her work explores the toxicological impacts of nanoparticles, pharmaceuticals, and environmental exposures, as well as the protective effects of antioxidants and stem cells—offering a well-rounded scientific profile.

  5. Professional Engagement
    Active member of Egyptian Society of Histology and Cytology and Medical Professions Syndicate, and involved in scientific conferences and training workshops.

  6. Methodological Strength
    Her skills in light/electron microscopy and immunohistochemical techniques indicate deep technical expertise.

⚙️ Areas for Improvement:

  1. Expand to International Collaborations
    Engaging in collaborative research with international institutions can increase visibility and impact.

  2. Publication in Higher Impact Journals
    While she has multiple publications, targeting high-impact Q1 journals can elevate the academic value of her research.

  3. Grant Funding & Project Leadership
    Applying for external research grants and leading funded projects would further enhance her research profile.

  4. Clinical Translation
    Bridging her findings from animal studies to clinical or translational research can broaden applicability.

🎓 Education:

Dr. Noura Mekawy earned her M.B.B.Ch. degree in Medicine and General Surgery from Zagazig University in October 2006, graduating with an excellent grade. Her strong academic foundation led her to pursue postgraduate studies in Histology and Cell Biology. In May 2012, she was awarded a Master’s degree with a thesis titled “The Effect of Maternal Exposure to Di (2-ethylhexyl) phthalate on The Lung of Albino Rat Offspring (Histological and Immunohistochemical Study).” She continued her academic progression by earning her M.D. in Basic Medical Sciences (Histology and Cell Biology) in January 2017. Throughout her studies, Dr. Mekawy demonstrated outstanding academic performance and developed a deep interest in cellular biology and histopathology. Her educational background reflects her commitment to advancing medical science through both practical research and academic instruction.

🧪 Experience:

Dr. Noura Mekawy began her academic career as a Demonstrator in the Histology and Cell Biology Department at Zagazig University in August 2008. She served in this role until May 2012, when she was promoted to Assistant Lecturer. In January 2017, following the completion of her M.D., she assumed the position of Lecturer in the same department. With over 15 years of experience in teaching and laboratory work, Dr. Mekawy has become proficient in histological techniques, immunohistochemistry, and electron microscopy. She is also skilled in data analysis using SPSS and Microsoft Office tools. Her responsibilities include teaching, supervising research projects, and contributing to curriculum development. Additionally, she has participated in educational quality assurance workshops and continues to mentor students and junior faculty members. Her teaching experience, combined with hands-on laboratory expertise, makes her a well-rounded educator and researcher.

🔬 Research Focus:

Dr. Mekawy’s research primarily focuses on histopathological and immunohistochemical changes in response to environmental, chemical, and pharmaceutical exposures in animal models. Her investigations are centered on understanding tissue damage and repair mechanisms in organs like the liver, lungs, testes, heart, submandibular glands, and the central nervous system. A consistent theme across her work is evaluating the protective or therapeutic roles of natural substances and pharmacological agents, including antioxidants like Vitamin E, Nigella sativa, and Zingerone, as well as advanced treatments such as salivary exosomes and stem cells. She integrates light microscopy, electron microscopy, and molecular biology techniques in her research. Dr. Mekawy is also engaged in evaluating the histological effects of nanoparticles and energy drinks on various tissues. Her contributions are valuable for toxicological assessment and potential therapeutic innovations, contributing to public health and medical safety.

📚 Publications Top Notes:

  1. 🧪 Effect of Silver Nanoparticles on Testes of Prepubertal Male Albino Rats and the Possible Protective Role of Vitamin E

  2. ⚠️ Hepatic Changes under the Effect of Red Bull Energy Drinks and its Withdrawal in Adult Male Albino Rats

  3. 💧 Therapeutic Role of Salivary Exosomes in Improving Histological and Biochemical Changes Induced by Duct Ligation in Submandibular Glands

  4. ❤️ The Possible Protective Effect of Zingiber Officinale on Cyclophosphamide-Induced Cardiotoxicity

  5. 👁️ Protective Effect of Chrysin on Corneal Structural Alterations Induced by Sofosbuvir

  6. 🧬 Nicorandil and Bone Marrow-Derived Mesenchymal Stem Cells in Ureteric Obstruction Recovery

  7. 🧠 Effect of Zinc Oxide Nanoparticles on Cerebellar Cortex of Adult Male Albino Rats

  8. 🥼 Protective Role of Ghrelin versus its Combination with Zingerone on Gastric Ischemic-Reperfusion

  9. 🔊 Effect of Low Frequency Noise on Heart and Lung & Role of Vitamin C

  10. 💪 Nandrolone Effect on Cardiac Muscle and Role of Nigella Sativa

🧾 Conclusion:

Dr. Noura Mekawy exhibits the hallmarks of a dedicated, capable, and innovative researcher in medical science. With over a decade of academic and research experience, she has made valuable contributions to experimental histology and cell biology. Her work is methodologically sound, thematically diverse, and medically relevant. The strength of her research, consistent publication record, and academic integrity make her a highly suitable candidate for the Best Researcher Award. Continued growth in publication quality, global collaboration, and translational research will further enhance her already impressive academic journey.