Sabir khan | Epidemiology | Best Researcher Award

Published on by Cell Biologist

Dr. Sabir khan | Epidemiology | Best Researcher Award

Jinfeng Laboratory, Chongqing | China

Dr. Sabir Khan’s research focuses on transcription factors, gene expression regulation, and the biosynthetic pathways of antibiotics. His work integrates microbiology and synthetic biology to explore the molecular mechanisms underlying fungal and bacterial diseases. He has contributed significantly to understanding antifungal susceptibility and the development of resistance mechanisms in pathogenic microorganisms. In addition, his studies on glioma (brain cancer) investigate microbial interactions and secondary metabolites that may offer therapeutic potential. His research extends to fermentation technology, optimizing microbial processes for enhanced antibiotic production. Dr. Khan’s postdoctoral research emphasizes ecological and synthetic biology approaches to manipulate microbial pathways for improved biosynthetic yields. By combining molecular genetics, microbiological assays, and bioinformatics tools, his work aims to identify regulatory networks and transcriptional controls involved in secondary metabolite production. Through this multidisciplinary approach, Dr. Khan contributes to the advancement of microbial biotechnology and the development of novel antimicrobial and anticancer strategies.

Profiles: Google Scholar | Orcid

Featured Publications: 

Khan, S., Bilal, H., Khan, M. N., Fang, W., Chang, W., Yin, B., Song, N. J., et al. (2024). Interleukin inhibitors and associated risk of candidiasis. Frontiers in Immunology, 28 March 2024.

Khan, S., Bilal, H., Shafiq, M., Zhang, D., Awais, M., Chen, C., Khan, M. N., et al. (2024). Distribution of Aspergillus species and risk factors for Aspergillosis from mainland China: A systematic analysis. Therapeutic Advances in Infectious Disease, 17 April 2024. https://doi.org/10.1177/2049936124xxxxx
(IF: 5.7)

Khan, S., Xu, X., Song, J., Wu, P., Liu, X., Liu, J., Chen, K., Xu, Z., Wu, H., & Zhang, B. (2022). Crosstalk of TetR-like regulator SACE_4839 and a nitrogen regulator for erythromycin biosynthesis. Applied Microbiology and Biotechnology, 106, 12345–12356.

Liu, Y.#, Khan, S.#, Wu, P.#, Liu, L., Li, B., Ni, J., Zhang, H., Chen, K., Wu, H., & Zhang, B. (2021). Uncovering and engineering mini-regulatory network of the TetR-family regulator SACE_0303 for yield improvement of erythromycin in Saccharopolyspora erythraea. Frontiers in Bioengineering and Biotechnology, 9, 715234.

Khan, S.†, Cai, L.†, Bilal, H., Khan, M. N., Fang, W., Zhang, D., & Yao, F. (2023). An 11-year retrospective analysis of candidiasis epidemiology, risk factors, and antifungal susceptibility in a tertiary care hospital in China. Scientific Reports, 13, 5678.

Khan, S.†, Hou, B., Khan, M. N., Shafiq, M., Cai, L.†, Fang, W., Wang, Q., Bilal, H., & Zeng, Y. (2025). A three-year retrospective analysis of microbial species and key biomarkers associated with wound infections in Shantou Hospital, China. Frontiers in Cellular and Infection Microbiology, 15, 15456.

Khan, S., Hameed, M. F., Zafar, I., Bibi, R., Mohany, M., Nazir, S., Kamal, M. A., & Shafiq, M. (2024). Synthesis, characterization, and pharmacological evaluation of Zn4O(BDC)3: Anticancer, antidiabetic, and drug delivery potential. Medicinal Chemistry, 20(3), 145–157.

Sevgi Kolayli | Microbiology | Best Researcher Award

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Ms. Sevgi Kolayli | Microbiology | Best Researcher Award

Ms. Sevgi Kolayli | Karadeniz Technical University | Turkey

Prof. Dr. Sevgi Kolaylı is a distinguished biochemist and food scientist at Karadeniz Technical University, Turkey. With a career spanning over 25 years, she has made pioneering contributions in the fields of antioxidant activity, natural product chemistry, and food biochemistry, especially with respect to bee products such as honey, propolis, and bee bread. Her research explores the biochemical properties and therapeutic potentials of these natural substances, integrating analytical chemistry with toxicology and nutrition. She has authored numerous articles in international journals, demonstrating her scientific leadership and collaborative spirit. Dr. Kolaylı’s work not only furthers academic understanding but also provides practical insights into functional foods, public health, and sustainable agriculture. Recognized for her scientific excellence and innovation, she continues to mentor students and researchers, contributing significantly to science at national and global levels.

Publication Profiles: 

Orcid
Google Scholar
Scopus

Education:

Prof. Dr. Sevgi Kolaylı completed her undergraduate studies in Chemistry at Karadeniz Technical University, Turkey. She pursued postgraduate studies in Biochemistry, earning her Master’s and Ph.D. from the same institution. Her doctoral research focused on the biochemical analysis of natural products and their antioxidant capacities, with a special emphasis on enzymatic activities in fish and bioactive compounds in plant sources. Over the years, she has expanded her academic portfolio by attending international workshops, symposia, and scientific training, continually refining her skills in analytical methods such as chromatography, spectroscopy, and molecular characterization. Her solid educational foundation has enabled her to bridge the gap between traditional biochemical research and applied nutritional science. She remains actively engaged in academic development through her roles in teaching, supervision, and curriculum innovation at Karadeniz Technical University.

Experience:

Prof. Dr. Sevgi Kolaylı has served in various academic and research capacities at Karadeniz Technical University. Starting as a research assistant, she has risen through the academic ranks to become a full professor. Her career includes teaching undergraduate and postgraduate courses in biochemistry, food chemistry, and analytical techniques, while also supervising numerous MSc and PhD theses. Dr. Kolaylı has been a principal investigator in several national and international research projects focused on the bioactivity and safety of food-based natural compounds. She is a respected reviewer for several peer-reviewed journals and has collaborated with researchers from Algeria, Germany, and across Türkiye. Her strong laboratory and analytical experience, combined with leadership in scientific projects, underscore her capacity for impactful research. Additionally, she contributes to scientific committees, journal editorial boards, and serves as an evaluator for research funding bodies.

Research Focus:

Prof. Dr. Sevgi Kolaylı’s research centers on the biochemical evaluation of natural products, particularly those derived from bee-related sources such as honey, propolis, and bee bread. Her investigations focus on antioxidant activity, phenolic content, and bioactive characterization, aiming to understand their therapeutic and nutritional value. She uses advanced analytical techniques (e.g., HPLC, HRMS, spectrophotometry) to identify bioactive compounds and assess their antioxidant, antimicrobial, antiviral, and anticancer potentials. A significant portion of her work has examined regional differences in natural products, correlating botanical origin with chemical composition. Her newer research explores food enrichment using natural antioxidants and toxicity assessments of honey containing grayanotoxins. This multidisciplinary approach integrates food science, toxicology, and molecular biology, contributing to the development of functional foods and nutraceuticals. Prof. Kolaylı’s scientific vision is geared towards advancing public health through safe, natural, and effective bioactive substances.

Publications Top Notes: 

  1.  Comparative study on antioxidant enzyme activities and lipid peroxidation in different fish species – Turkish J. Zoology

  2.  Antioxidant enzymes in freshwater vs. seawater adapted trout – J. Biochem. Mol. Toxicol.

  3.  Chemical & antioxidant properties of cherry laurel fruit – J. Agric. Food Chem.

  4.  Does caffeine bind to metal ions? – Food Chemistry

  5.  Stereoselective photochemistry of methoxy chalcones – Turkish J. Chemistry

  6.  Essential oils of Centaurea spp. and their antimicrobial activity – Phytochemistry

  7.  Photocyclization and microbial activity of chalconoid compounds – J. Photochem. Photobiol. A

  8.  Synthesis of heterocycles as antioxidant/anticancer agents – Archiv der Pharmazie

  9.  Synthesis and antioxidant activities of triazol-5-one derivatives – Indian J. Chemistry

  10.  New triazole derivatives and their antioxidant properties – Asian J. Chemistry

Conclusion:

In conclusion, Prof. Dr. Sevgi Kolaylı exemplifies the qualities of a well-rounded, impactful, and visionary researcher whose work has significantly advanced the understanding of bioactive compounds in food and natural products. Her sustained excellence in publishing, mentoring, and interdisciplinary collaboration makes her highly suitable for the Best Researcher Award. Her ability to combine fundamental biochemical insights with real-world health applications, especially in the areas of antioxidant research and bee product functionality, showcases her as not just a researcher, but a contributor to global health and nutrition science. With minor enhancements in innovation dissemination and global visibility, she can further establish herself as a leading figure in the international scientific community. Based on the strength of her scientific record, impact, and innovation potential, she is a highly deserving nominee for the Best Researcher Award.

 

 

Romain Villéger | Host-bacteria interactions | Cell Metabolism Award

Published on by Cell Biologist

Assist. Prof. Dr. Romain Villéger | Host-bacteria interactions | Cell Metabolism Award

Assist. Prof. Dr. Romain Villéger , Université de Poitiers , France

Dr. Romain Villéger is an Assistant Professor at the University of Poitiers, France, in the Ecology & Biology of Interactions (EBI) lab, within the Microorganisms-Hosts-Environments (MHE) team. With a Ph.D. from the University of Limoges, his work explores the intricate interactions between probiotics and host cells. He has held postdoctoral positions at the University of Bordeaux and the University of Texas Medical Branch, USA, focusing on microbiota-host relationships and metabolomics. Dr. Villéger’s research aims to unravel the role of bacterial interactions, particularly in the context of gastrointestinal health, microbiota, and cancer. His research has led to significant advancements in understanding microbial pathogenesis, including the effects of probiotics and endocrine disruptors on host cell metabolism. A dedicated researcher, he has contributed to numerous scientific publications and currently leads several high-impact projects on bacteria-host interactions.

Publication Profile:

Scopus

Strengths for the Award:

  1. Expertise in Metabolomics: Dr. Romain Villéger’s extensive work in metabolomics, especially in the context of host-bacteria interactions, positions him as a strong candidate for the Cell Metabolism Award. His research on bacterial influence on host cellular metabolism and gut microbiota interactions contributes significantly to the field of cellular metabolism.
  2. Innovative Research Contributions: His research, particularly on the metabolic changes during amoeba-Legionella interactions, showcases a novel approach to understanding microbial pathogenesis. By identifying metabolic vulnerabilities in pathogens, his work has the potential for therapeutic applications, thus addressing fundamental questions in cell metabolism.
  3. Multidisciplinary Approach: Dr. Villéger combines microbiology, immunology, and metabolomics, which enriches his contributions to cellular metabolism. His research is collaborative, evidenced by numerous projects across different institutions and fields, indicating a broad and innovative approach to the subject.
  4. Publications and Impact: He has a strong publication record, with numerous articles in peer-reviewed journals (19 publications), with high visibility in top-tier journals such as British Journal of Cancer, Frontiers in Cellular and Infection Microbiology, and Environmental Microbiology Reports. This demonstrates his influence and impact in the scientific community.
  5. Research Leadership: As the principal investigator of multiple projects, including those on the effects of phthalates on gut microbiota and cancer development, Dr. Villéger has demonstrated leadership in advancing scientific knowledge in areas that intersect with cell metabolism, host-microbe interactions, and metabolic changes in disease.

Areas for Improvement:

  1. Broader Clinical Translation: While his research shows deep insights into fundamental mechanisms, further work on translating these findings into practical clinical applications or therapeutic interventions would strengthen his impact in applied cellular metabolism.
  2. Interdisciplinary Team Development: While Dr. Villéger collaborates with many renowned researchers, fostering additional interdisciplinary partnerships could enrich his research by incorporating diverse techniques and perspectives from fields like drug development or personalized medicine.
  3. Expanding Metabolomic Toolkits: His research could benefit from exploring emerging and cutting-edge techniques in metabolomics, like single-cell analysis or multi-omics approaches, to gain deeper insights into cellular metabolism at the individual cell level.

Education:

Dr. Villéger completed his Ph.D. at the University of Limoges, where his thesis focused on the interactions between probiotics and host cells. His postdoctoral work spans institutions in France, the USA, and beyond, each contributing valuable insights into microbial-host dynamics and cellular microbiology. At the University of Bordeaux, he developed metabolomic approaches using GC/MS to study microbiota interactions. Later, at the University of Texas Medical Branch, he delved deeper into the effects of probiotics on intestinal homeostasis. Further postdoctoral experiences at the University of Clermont Auvergne involved examining the relationship between E. coli and colorectal cancer. Through these experiences, Dr. Villéger has gained expertise in microbiota research, cell biology, and metabolic analysis, providing a foundation for his ongoing work in the field. His education has provided a strong interdisciplinary framework, integrating microbiology, molecular biology, and toxicology into his research.

Experience:

Dr. Villéger has accumulated extensive experience in both academic and research settings. After earning his Ph.D. in 2014, he completed several postdoctoral positions, with notable work at the University of Bordeaux, where he pioneered metabolomics techniques for microbiota research. His tenure at the University of Texas Medical Branch expanded his focus to the effects of probiotics on intestinal homeostasis. Additionally, his work at the University of Clermont Auvergne involved exploring the connection between microbial interactions and cancer. Since joining the University of Poitiers in 2020 as an Assistant Professor, Dr. Villéger has led several research projects, including investigating the impact of endocrine disruptors on colorectal cancer development. He is also a leader in metabolomics and microbial pathogenesis, with a particular focus on bacteria-host interactions and microbiota modulation. His research has contributed to numerous publications and collaborations with institutions worldwide, showcasing his ability to manage complex research projects.

Research Focus:

Dr. Villéger’s research primarily focuses on bacteria-host interactions, gut microbiota, and cellular microbiology, with a special interest in how microbial populations affect host metabolism. His work integrates metabolomics, a powerful tool for studying metabolic processes, to better understand microbial influence on host cells. Dr. Villéger’s recent studies explore the role of oxidative stress in microbial infections, including Legionella pneumophila’s subversion of host immune defenses during infection. He has also investigated the impact of endocrine disruptors on microbial virulence, providing insights into the potential links between environmental factors and microbial pathogenesis. His contributions to understanding the microbiota-gut-brain axis, particularly in the context of colorectal cancer, emphasize the metabolic changes induced by bacterial interactions. Dr. Villéger’s research aims to identify biomarkers for disease and therapeutic interventions, with a broader goal of advancing precision medicine through a better understanding of the cellular and metabolic processes that underlie microbial-host dynamics.

Publications Top Notes:

  1. Legionella pneumophila subverts the antioxidant defenses of its amoeba host Acanthamoeba castellanii 💥🦠
  2. Increased Activity of MAPKAPK2 within Mesenchymal Cells as a Target for Inflammation-Associated Fibrosis in Crohn’s Disease 🔬🧬
  3. Exposure to endocrine disruptors promotes biofilm formation and contributes to increased virulence of Pseudomonas aeruginosa 💧🦠
  4. Loss of alcohol dehydrogenase 1B in cancer-associated fibroblasts: contribution to the increase of tumor-promoting IL-6 in colon cancer 🧬🦠
  5. Effect of endocrine disruptors on bacterial virulence 🌿🧪
  6. Proteomic analysis of Acanthamoeba castellanii response to Legionella pneumophila infection 🔬🦠
  7. Disruption of retinol-mediated IL-6 expression in colon cancer-associated fibroblasts: new perspectives on the role of vitamin A metabolism 🧬🍊
  8. Microbiota medicine: towards clinical revolution 🌍💊
  9. Deletion of cystathionine-γ-lyase in bone marrow-derived cells promotes colitis-associated carcinogenesis 🔬🦠
  10. Prebiotic Isomaltooligosaccharide Provides an Advantageous Fitness to the Probiotic Bacillus subtilis CU1 🍞🦠

Conclusion:

Dr. Romain Villéger is a highly qualified candidate for the Cell Metabolism Award. His research contributions in understanding microbial influence on cellular metabolism and gut health, combined with his innovative approach to metabolomics, make him stand out in the field. His work bridges basic science and potential clinical applications, positioning him as a key figure in the ongoing exploration of microbial and metabolic influences on host physiology. With some expansion into clinical applications and further exploration of new metabolomics techniques, his contributions could significantly impact both scientific knowledge and medical practice.