Hyung Joon Kim | Oral cancer | Best Researcher Award

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Prof. Dr. Hyung Joon Kim | Oral cancer | Best Researcher Award

Prof. Dr. Hyung Joon Kim, Pusan National University School of Dentistry, South Korea

Dr. Hyung Joon Kim is a distinguished Professor at the Department of Oral Physiology, School of Dentistry, Pusan National University. With a robust foundation in molecular biology and dental sciences, Dr. Kim has made significant contributions to the understanding of bone biology, particularly in the contexts of periodontitis, osteoclast/osteoblast function, and bone metastasis. His research bridges fundamental science and clinical application, focusing on regenerative therapies using dental cells. Over the years, he has held key research and academic positions at Seoul National University and Kyung Hee University, where he advanced investigations into bone metabolism and periodontal regeneration. An accomplished academic, Dr. Kim has published extensively in high-impact journals, exploring complex signaling pathways and therapeutic targets in bone-related diseases. His work stands out for its interdisciplinary approach and translational potential, positioning him as a strong candidate for the Best Researcher Award in biomedical sciences.

Publication Profile: 

Scopus

Orcid

✅ Strengths for the Award:

  1. Strong Academic Background
    Dr. Kim holds a BS in Molecular Biology and a PhD in Dentistry from two of South Korea’s top institutions, establishing a multidisciplinary foundation in both basic science and clinical research.

  2. Focused and Impactful Research
    His research areas—osteoclast/osteoblast biology, bone metastasis, dental stem cell therapy, and periodontitis—address critical global health issues. His work bridges fundamental science and therapeutic applications, enhancing its clinical relevance.

  3. Impressive Publication Record
    With multiple peer-reviewed papers in internationally recognized journals like J Bone Miner Res, Int J Mol Sci, and Cells, Dr. Kim has demonstrated consistent and high-quality scientific output.

  4. Leadership and Experience
    He has held senior and professorial positions at leading research centers and universities for over a decade, highlighting his expertise, leadership, and mentorship skills.

  5. Interdisciplinary Approach
    His integration of molecular biology, regenerative dentistry, and systemic disease pathways reflects innovation and cross-disciplinary thinking—key for future-focused research.

🔧 Areas for Improvement:

  1. Global Collaboration & Outreach
    While Dr. Kim has a strong national profile, increasing international collaborations, joint publications, or involvement in global research consortia could further elevate his influence and recognition.

  2. Translational and Clinical Application
    More emphasis on clinical trials or patent filings based on his lab’s findings would help translate laboratory success into real-world impact, strengthening his candidacy for awards focused on innovation.

  3. Funding and Grants Visibility
    Public visibility of high-impact grants or funding awards received would reinforce the trust and investment the research community places in his work.

🎓 Education:

Dr. Hyung Joon Kim began his academic journey at Pusan National University, where he earned his Bachelor of Science in Molecular Biology (1996–2004). Building on this strong foundation in biological sciences, he pursued advanced research in dental sciences, obtaining a Ph.D. from the Department of Dentistry at Seoul National University (2004–2009). His doctoral work integrated molecular biology with dental pathophysiology, setting the stage for his later specialization in bone metabolism and regenerative medicine. His multidisciplinary educational background enabled him to explore complex biological processes with a clinical perspective, particularly in understanding the mechanisms of osteoclast and osteoblast regulation, and their roles in periodontitis and systemic disease. The combination of molecular insight and clinical relevance in his education forms the cornerstone of his innovative research, equipping him to contribute meaningfully to the academic and clinical dental community.

💼 Professional Experience:

Dr. Kim’s professional career spans over 15 years of dedicated research and teaching. He began as a Senior Researcher (2009–2013) at the Bone Metabolism Research Center, Seoul National University, where he led projects on osteoclast function and bone pathology. He then served as a Research Professor (2013–2014) at the Tooth and Periodontal Tissue Regeneration Center, Kyung Hee University, further deepening his expertise in dental tissue engineering. Since 2014, Dr. Kim has been serving as an Associate Professor (now Professor) at the School of Dentistry, Pusan National University, where he leads multiple research initiatives and mentors future dental researchers. His career reflects a consistent focus on translational bone biology, contributing not only to scientific advancement but also to academic excellence. His blend of research innovation and educational leadership makes him an impactful figure in oral physiology and regenerative medicine.

🔬 Research Focus:

Dr. Hyung Joon Kim’s research is centered on understanding the cellular and molecular mechanisms of bone regeneration and destruction, particularly through the lens of osteoclast and osteoblast biology. He explores how inflammatory signals and cytokines influence these bone cells, contributing to diseases like periodontitis and bone metastasis. His second major interest lies in investigating the paracrine mechanisms in periodontal disease and identifying therapeutic targets for halting bone loss. Dr. Kim is also pioneering the cellular therapeutic application of dental stem cells for tissue regeneration, merging basic cell biology with clinical innovation. Additionally, he investigates the systemic implications of periodontal disease, linking oral health to broader systemic conditions. Through his research, he aims to develop more effective and targeted treatments for bone-related diseases, using a combination of molecular insights, stem cell therapy, and pharmacological interventions.

📚 Publications Top Notes:

📖 Elevated Expression of Cathepsin K in Periodontal Ligament Fibroblast by Inflammatory Cytokines Accelerates Osteoclastogenesis via Paracrine Mechanism in Periodontal Disease. (2021)
📖 Gastrin-Releasing Peptide (GRP) Stimulates Osteoclastogenesis in Periodontitis. (2021)
📖 Assessing the effects of cyclosporine A on osteoblastogenesis, osteoclastogenesis, and angiogenesis mediated by human periodontal ligament stem cells. (2020)
📖 Connective tissue growth factor (CTGF) regulates the fusion of osteoclast precursors by inhibiting Bcl6 in periodontitis. (2020)
📖 A CTGF-RUNX2-RANKL Axis in Breast and Prostate Cancer Cells Promotes Tumor Progression in Bone. (2020)
📖 Zoledronate Enhances Osteocyte-Mediated Osteoclast Differentiation by IL-6/RANKL Axis. (2019)
📖 Calcium-Phosphate Crystals Promote RANKL Expression via the Downregulation of DUSP1. (2019)
📖 Effects of Hispidulin on the Osteo/Odontogenic and Endothelial Differentiation of Dental Pulp Stem Cells. (2024)

🧾 Conclusion:

Dr. Hyung Joon Kim stands out as a highly qualified candidate for the Best Researcher Award. His extensive research in bone physiology, dental stem cells, and systemic disease mechanisms reflects both scientific rigor and practical application. With a proven track record of leadership, academic productivity, and impactful focus areas, he exemplifies the qualities of an innovative and dedicated researcher.

Paola Zagami | Cancer Cell Biology | Young Scientist Award

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Dr. Paola Zagami | Cancer Cell Biology | Young Scientist Award

Dr. Paola Zagami , IEO european institute of oncology University of Milan , Italy

Dr. Paola Zagami is an accomplished Italian physician and medical oncologist currently working at the European Institute of Oncology (IEO) in Milan. She specializes in clinical and research oncology, focusing on breast cancer. With a strong academic background and passion for advancing cancer treatment, Dr. Zagami has contributed to numerous studies on innovative therapies, particularly immunotherapy and endocrine treatments in breast cancer. She is recognized for her expertise in cancer genomics and the impact of immune checkpoint inhibitors in cancer treatment. Dr. Zagami’s work reflects a blend of clinical practice and research, as she actively collaborates with experts in the oncology field to improve patient outcomes.

Publication Profile:

Scopus

Strengths for the Award:

Dr. Paola Zagami is an exceptional candidate for the Research for Young Scientist Award due to her profound contributions to oncology research, particularly in breast cancer treatment and clinical trials. Her work on immune checkpoint inhibitors, endocrine therapies, and the genomics of breast cancer demonstrates her expertise in precision oncology. Dr. Zagami has been involved in high-impact publications and collaborative international studies, such as her work on metastatic triple-negative breast cancer and the development of novel cancer therapies. Her clinical and research skills, combined with her ability to contribute to the scientific community through publications and awards, make her a highly qualified and promising young scientist. Furthermore, her commitment to gender equity in pharmacological research and clinical trials aligns with the future direction of oncology research, making her a strong contender for the award.

Areas for Improvement:

While Dr. Zagami has made significant strides in breast cancer research, there are opportunities to broaden her research focus to include other cancer types, enabling her to contribute to a wider array of oncological studies. Additionally, further involvement in leading large-scale clinical trials could enhance her leadership in the field. Expanding her research network internationally could facilitate more diverse collaborations and broader research impact.

Education:

Dr. Zagami earned her medical degree (MD) and has since pursued extensive education in the field of oncology. In 2021, she received a scholarship from the IEO-Monzino Foundation, focusing on clinical research in oncology. She further honed her expertise by earning the AMMI award in 2023 for her work on gender equity in pharmacological research. This education in clinical research positions Dr. Zagami as a thought leader in her field, with a commitment to investigating new treatments and approaches in cancer care.

Experience:

Dr. Zagami’s professional career began as an oncological clinical researcher, where she focused on the development of targeted therapies and the clinical impact of cancer treatments. Since 2024, she has been serving as a medical oncologist at the European Institute of Oncology (IEO) in Milan, contributing to both clinical and research activities. Throughout her career, Dr. Zagami has gained experience in advanced oncology treatments, particularly in immunotherapy and endocrine therapies for breast cancer. She works closely with interdisciplinary teams to design and conduct clinical trials, improving personalized cancer care. Dr. Zagami’s research collaborations have resulted in several publications in prestigious journals, reflecting her expertise and commitment to enhancing cancer treatment strategies.

Experience:

Dr. Zagami’s professional career began as an oncological clinical researcher, where she focused on the development of targeted therapies and the clinical impact of cancer treatments. Since 2024, she has been serving as a medical oncologist at the European Institute of Oncology (IEO) in Milan, contributing to both clinical and research activities. Throughout her career, Dr. Zagami has gained experience in advanced oncology treatments, particularly in immunotherapy and endocrine therapies for breast cancer. She works closely with interdisciplinary teams to design and conduct clinical trials, improving personalized cancer care. Dr. Zagami’s research collaborations have resulted in several publications in prestigious journals, reflecting her expertise and commitment to enhancing cancer treatment strategies.

Research Focus:

Dr. Zagami’s research focus is primarily centered around the treatment of breast cancer, particularly in the areas of immunotherapy, endocrine therapy, and personalized medicine. She has been involved in research on immune checkpoint inhibitors for metastatic triple-negative breast cancer and the clinical implications of genomic alterations in breast cancer. Dr. Zagami is also dedicated to investigating the safety and efficacy of novel cancer therapies, particularly in early-phase clinical trials. Her research interests also include the study of gender equity in pharmacological research and the integration of molecular diagnostics in clinical trials for metastatic breast cancer. She is committed to advancing precision oncology by studying the genetic and clinical landscape of breast cancer to enhance patient outcomes and treatment strategies.

Publications Top Notes:

  1. Immunotherapy in the treatment landscape of hormone receptor-positive (HR+) early breast cancer: is new data clinical practice changing?
  2. Triple negative breast cancer: pitfalls and progress.
  3. Association of PIK3CA Mutation With Pathologic Complete Response and Outcome by Hormone Receptor Status and Intrinsic Subtype in Early-Stage ERBB2/HER2-Positive Breast Cancer.
  4. Endocrine therapy for early breast cancer in the era of oral selective estrogen receptor degraders: challenges and future perspectives.
  5. Effect of age on safety and efficacy of novel cancer drugs investigated in early-phase clinical trials.
  6. Immunotherapy for patients with metastatic triple-negative inflammatory breast cancer (INCORPORATE): An international cohort study.

Conclusion:

Dr. Paola Zagami is undoubtedly a rising star in the field of oncology. Her combination of clinical experience, research accomplishments, and passion for improving cancer treatments positions her as a highly deserving candidate for the Research for Young Scientist Award. As she continues to advance her work in oncology, her future contributions have the potential to significantly impact cancer care and research globally. With some further expansion in her research focus and leadership roles, Dr. Zagami is poised to be an influential figure in oncology for years to come.