Tao Liang | Cell Death Pathway | Best Researcher Award

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Mr. Tao Liang | Cell Death Pathway | Best Researcher Award

Mr. Tao Liang, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, China

Dr. Tao Liang is an accomplished medicinal chemist with deep expertise in small molecule drug design, synthesis, and pharmacological evaluation. Originating from Dancheng County, Henan Province, and currently residing in Wuhu City, Anhui Province, Dr. Liang is an Assistant Researcher at The Second Affiliated Hospital of Wannan Medical College. He earned his Doctor of Medicine from Shandong University, a leading institution under China’s “Double First-Class” initiative. With over 7 first-author SCI publications and multiple national invention patents, his research significantly contributes to targeted cancer therapies, especially involving HDAC6-selective inhibitors and Bax agonists. He has successfully led key projects funded by the Anhui Provincial Government and participated in prestigious National Natural Science Foundation of China projects. Known for both scientific depth and innovation, Dr. Liang has been recognized with national-level scholarships and university-wide honors for outstanding research achievements and academic excellence.

Publication Profile:

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✅ Strengths for the Award:

  1. High-Impact Publications

    • Authored 7 first-author SCI papers, including publications in top-tier journals like Acta Pharm Sin B (IF 14.907) and J Med Chem (IF 8.039).

    • Published extensively on HDAC6 isoform-selective inhibitors and apoptosis-targeting small molecules, a niche and cutting-edge domain in anticancer drug research.

  2. Research Leadership & Innovation

    • Serves as Principal Investigator for two key provincial research projects focusing on selective cancer therapies.

    • Demonstrated innovation in designing dual-target inhibitors (MMP/HDAC) and novel Bax agonists.

  3. National-Level Collaborations

    • Participated in major National Natural Science Foundation of China projects (5 total), totaling over RMB 2 million in funding.

    • Engaged with multidisciplinary teams and key opinion leaders, including renowned researchers such as Prof. Hao Fang and Prof. Xuben Hou.

  4. Academic Recognition

    • Winner of prestigious honors such as the National Scholarship, Outstanding Doctoral Graduate, and guest speaker at elite academic forums.

    • Recipient of 15+ national and university-level awards, including innovation prizes and scholarships.

  5. Patent Contributions

    • Holds 4 national invention patents, reflecting translational potential and real-world application of his research outputs.

🔧 Areas for Improvement:

  1. International Visibility & Collaboration

    • Current research impact is primarily within domestic circles (China). Engaging in cc, postdoctoral exchanges, or publishing with international co-authors would elevate recognition.

  2. Clinical Translation Pipeline

    • Despite strong preclinical development, there is no direct evidence of transition to clinical trials or industrial commercialization. Partnering with biotech/pharma could increase translational outcomes.

  3. Leadership Beyond Research

    • As an early-career researcher, administrative leadership (e.g., lab director, national committee memberships) may still be developing. Building a research group or mentoring PhD students would strengthen this.

  4. Interdisciplinary Expansion

    • Expertise is strong in medicinal chemistry, but cross-disciplinary projects involving AI/drug discovery, systems biology, or clinical oncology could broaden the impact.

🎓 Education:

Dr. Tao Liang received his Bachelor of Science in Pharmacy from Shandong University (2013.9–2017.6), one of China’s elite institutions under the National “985 Project” and “Double First-Class” initiative. Continuing at the same university, he pursued a Master’s and Ph.D. in Medicinal Chemistry, earning a Doctor of Medicine degree in 2022. Shandong University, renowned for its Ministry of Education Class A-rated disciplines, provided Dr. Liang with a rigorous scientific environment and access to state-of-the-art research facilities. During his academic training, he developed a strong foundation in chemical biology, natural product synthesis, and drug development. His educational journey has been marked by consistent excellence, earning him accolades like National Scholarships and Outstanding Graduate awards. His academic credentials and extensive research during his Ph.D. have positioned him as a leading young researcher in the field of medicinal chemistry in China.

💼 Work Experience:

Since August 2022, Dr. Tao Liang has been serving as an Assistant Researcher at The Second Affiliated Hospital of Wannan Medical College. His research focuses on the structural design, chemical synthesis, and pharmacological activity evaluation of small molecule drugs, particularly targeting HDAC isoforms and apoptotic regulators like Bax. He currently leads two key projects: one on HDAC6-selective inhibitors and another on Bax agonists for cervical cancer therapy, funded by the Anhui Provincial Higher Education and Health Commission respectively. Previously, he participated in several high-impact national research projects, including two funded by the National Natural Science Foundation of China, focusing on anti-cancer drug discovery. His roles have involved both independent project leadership and critical collaboration within multidisciplinary teams. Dr. Liang’s work experience showcases his capabilities in translational medicinal chemistry research and positions him as a promising talent in pharmaceutical innovation.

🏆 Awards and Honors:

Dr. Tao Liang has received more than a dozen honors for his outstanding academic and research contributions. These include the prestigious National Scholarship (2021), Outstanding Doctoral Graduate of Shandong University (2022), and multiple first-class scholarships throughout his postgraduate studies. He was a special guest speaker at prominent forums like the “Haiyou Doctoral Forum” and “Lao Xu Talks about High Strategies.” His undergraduate years were equally distinguished, earning the first prize in the ‘Challenge Cup’ and honors like “Outstanding Graduate” and “Excellent Communist Youth League Member”. His early career was also decorated with international recognitions such as the First Prize for Innovation Results at the World University Students’ Pharmaceutical Garden Forum. These awards highlight both his academic brilliance and commitment to scientific advancement, affirming his eligibility and strength as a nominee for the Best Researcher Award.

🔬 Research Focus:

Dr. Tao Liang’s research centers on the design, synthesis, and biological evaluation of small molecule inhibitors with a primary focus on histone deacetylase 6 (HDAC6) isoform-selective inhibitors and Bax agonists for cancer therapy. His work integrates computational modeling, medicinal chemistry, and pharmacodynamics to create targeted therapies aimed at epigenetic modulation and apoptosis induction in cancer cells. He has actively contributed to national-level projects exploring dual-target inhibitors (MMP/HDAC) and small molecule interventions for Mcl-1 and striatal enriched tyrosine phosphatase (STEP) targets. Dr. Liang is particularly recognized for his innovation in optimizing chemical scaffolds for selective inhibition and minimizing off-target effects. Through collaborative and independent research, he aims to address challenges in chemotherapeutic resistance and toxicity. His scientific pursuits align with current global trends in precision oncology, making significant strides in targeted therapy development and laying a foundation for future clinical translation.

📚 Publications Top Notes:

  1. 📘 Design, synthesis and evaluation of structural optimization derived HDAC6 isoform-selective inhibitor – Bioorganic Chemistry, 2025

  2. 📗 Targeting histone deacetylases for cancer therapy: Trends and challenges – Acta Pharmaceutica Sinica B, 2023

  3. 📙 Potential applications of BPFP1 in Bcl-2 protein quantification, carcinoma cell visualization, cell sorting and early cancer diagnosis – European Journal of Medicinal Chemistry, 2021

  4. 📕 Design, synthesis and biological evaluation of 3,4-disubstituted-imidazolidine-2,5-dione derivatives as HDAC6 selective inhibitors – European Journal of Medicinal Chemistry, 2021

  5. 📘 Recent Development of Novel HDAC6 Isoform-selective Inhibitors – Current Medicinal Chemistry, 2021

  6. 📗 HDAC–Bax Multiple Ligands Enhance Bax-Dependent Apoptosis in HeLa Cells – Journal of Medicinal Chemistry, 2020

  7. 📙 Design, Synthesis, and Biological Evaluation of 2,4-Imidazolinedione Derivatives as HDAC6 Isoform-Selective Inhibitors – ACS Medicinal Chemistry Letters, 2019

  8. 📕 Synthesis and Antiproliferative Activity of Thiadiazole Peptidomimetic Derivatives – Chinese Journal of Organic Chemistry, 2016

🧾 Conclusion:

Dr. Tao Liang is highly suitable for the Best Researcher Award, especially in the early- to mid-career researcher category. His extensive publication record, innovative medicinal chemistry work, leadership in funded projects, and impressive academic recognitions make him an exemplary candidate.

Prahlad Singh | Developmental Cell Biology | Best Researcher Award

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Prof. Prahlad Singh | Developmental Cell Biology | Best Researcher Award

Prof. Prahlad Singh , Guru Angad Dev Veterinary and Animal Sciences University , India

PRAHLAD SINGH is a distinguished scientist and academician with over 30 years of experience in veterinary science and animal husbandry. He currently serves as a Professor-cum-Nodal Officer at the MSVH&RRTC, Guru Angad Dev Veterinary and Animal Sciences University (GADVASU), Ludhiana. Prahlad’s expertise lies in veterinary gynecology and obstetrics, with significant contributions to reproductive health and cryobiology in livestock, particularly buffaloes. His academic journey has been complemented by his role as a leader in research programs and his involvement in international collaborations. Known for his leadership in managing major research and development projects, he also holds expertise in financial management, fiscal control, and strategic planning for research initiatives. Prahlad Singh’s commitment to education and research has been recognized in national and international circles, making him a key figure in veterinary sciences.

Publication Profile: 

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Strengths for the Award:

  1. Educational Background and Qualifications:

    • Prahlad Singh holds a Doctor of Philosophy (Ph.D.) in Veterinary Gynaecology and Obstetrics, a distinguished qualification in the field of Veterinary Science.
    • His career has been built on strong academic credentials, evidenced by his Bachelor’s in Veterinary Sciences and Animal Husbandry and Master’s in Veterinary Science (MVSc).

  2. Professional Experience:

    • He has more than 10 years of experience in a professor-cum-Nodal Officer role at the prestigious Guru Angad Dev Veterinary and Animal Sciences University in Punjab.
    • His involvement in high-level management and infrastructure development as a Nodal Officer demonstrates his leadership capabilities.
    • He has overseen major R&D programs with over 10 scientists under his leadership.

  3. Research Contributions and Publications:

    • Prahlad Singh’s research is highly impactful, with several quality publications in journals with NAAS ratings of 7.5 and above, including Cryobiology (NAAS rating 8.728), a highly regarded journal in the veterinary science community.
    • His work on cryoprotectants and sperm functionality in crossbred bulls and Murrah buffalo bulls is pioneering, contributing to the advancement of reproductive technologies in veterinary science.
    • The diversity in his research spans topics such as animal nutrition, fertility, cryobiology, and reproductive health, showcasing a broad, impactful influence on his field.
    • His contributions have been internationally recognized, with his research presented at global conferences like CRYO2022.

  4. International Exposure and Leadership in Training:

    • Singh has completed international training programs, such as at The Koret School of Veterinary Medicine in Israel, demonstrating a global perspective in his approach to veterinary sciences.
    • His leadership in organizing national and international collaborative programs for Krishi Vigyan Kendras further enhances his profile as a well-rounded academician.

  5. Impact on the Veterinary Field:

    • His work has far-reaching implications for improving livestock health, especially in fertility enhancement and nutrition for buffaloes and other livestock.
    • His role in enhancing fertility strategies and advancing reproductive practices has directly impacted small-holder dairy farmers in Punjab.

Areas for Improvement:

  1. Broader Outreach and Collaboration:

    • Although Prahlad Singh has extensive experience in national and international collaborations, his work could benefit from broader inter-disciplinary collaborations, particularly in fields that intersect with agriculture, environmental sciences, and sustainable farming practices.
    • Further expanding his research scope beyond reproductive health into other areas of livestock management and animal welfare could amplify his contributions to the global scientific community.

  2. Public Communication:

    • While Singh’s research has been highly successful in journals and conferences, increasing his presence in popular science and policy-level discussions could make his work more accessible to a larger audience, including policymakers and farmers.

  3. Grant Acquisition and Resource Management:

    • Though he has experience in financial management, his ability to manage large-scale funding and grant acquisition could be emphasized further. Stronger grant management skills will help in securing resources for larger collaborative projects.

Education:

PRAHLAD SINGH holds a Ph.D. in Veterinary Gynecology and Obstetrics from Punjab Agricultural University, Ludhiana, Punjab. He completed his Master’s degree (MVSc) in Veterinary Science, with a focus on reproductive health, at the same university. His academic career began with a Bachelor of Veterinary Science and Animal Husbandry (B.V.Sc. & A.H.) from SKUAST, Srinagar, and continued at HPKV, Palampur. His educational journey is marked by an impressive blend of rigorous research and practical application, particularly in veterinary science disciplines related to animal reproduction and cryobiology. Prahlad’s education, paired with numerous advanced training programs, including an international course at the Hebrew University of Jerusalem, has equipped him with both the theoretical and practical knowledge to contribute significantly to the academic and scientific community.

Experience:

With over 30 years of experience in the field of veterinary science, PRAHLAD SINGH has held several prominent academic and administrative positions. Currently, he serves as a Professor-cum-Nodal Officer at the MSVH&RRTC, GADVASU, Ludhiana, where he is responsible for managing major research projects and overseeing infrastructure development. Prahlad has also held leadership roles as Associate Director (Training)-cum-Programme Coordinator, where he supervised financial planning, resource management, and collaborated with national and international institutions. He has vast experience in veterinary research, specializing in reproductive health, cryobiology, and veterinary gynecology, and has led several interdisciplinary research teams. Prahlad’s extensive experience in teaching, research, and management has earned him recognition both within India and internationally. His ability to balance scientific research with strategic management has made him a leading figure in his field.

Awards and Honors:

PRAHLAD SINGH has been recognized for his significant contributions to veterinary science and research. He has received accolades for his leadership in establishing research centers and managing large-scale scientific programs. Prahlad has been honored for his role in developing national and international collaborations, particularly in cryobiology and reproductive health in livestock. He has also been recognized for his ability to secure funding and manage financial resources for research initiatives. His work has earned him a place at major international conferences and research symposia. Prahlad’s extensive publication record in high-impact journals, coupled with his work on innovative techniques in veterinary medicine, has solidified his status as an eminent scientist. His dedication to advancing veterinary science and mentoring the next generation of researchers has earned him numerous honors in recognition of his academic and research excellence.

Research Focus:

PRAHLAD SINGH’s research primarily focuses on reproductive health, cryobiology, and the application of advanced techniques in veterinary gynecology and obstetrics. His work on cryopreservation and the effect of cryoprotectants on sperm functional and kinetic parameters in buffaloes has contributed significantly to improving livestock breeding practices. Prahlad is also focused on understanding and enhancing fertility in livestock, especially in cattle and buffaloes, through innovative approaches to hormonal synchronization and artificial insemination. Additionally, his research includes the development of new methodologies for improving the quality of semen for artificial breeding. Prahlad is particularly interested in exploring the impacts of dietary supplements and other factors on metabolic and reproductive health. His expertise in the field of veterinary science makes him a valuable asset in the areas of animal husbandry, reproductive health, and the application of modern biotechnology in animal breeding.

Publications Top Notes:

  • Harneet Kour, Ravinder Singh Grewal, Prahlad Singh, Jaspal Singh Lamba, Jasmine Kaur, Shashi Nayyar (2023) – Influence of Dietary Cation-Anion Differences (DCAD) on Nutrient Intake, Milk Yield and Metabolic Parameters of Transition Buffaloes 🐃📄
  • Prahlad Singh, Munish Kumar Bedi, Sumit Singhal, Ashwani Kumar Singh, Ajeet Kumar, Mrigank Honparkhe (2022) – Effect of graphene oxide as cryoprotectant on post-thaw sperm functional and kinetic parameters of cross bred (HF X Sahiwal) and Murrah buffalo bulls 🧪🔬
  • Prahlad Singh, Deepak Sharma, Sumit Singhal, Ajeet Kumar, Ashwani Kumar Singh, Mrigank Honparkhe (2022) – Sodium Dodecyl Sulphate, N-Octyl β-D Glucopyranoside and 4-Methoxy Phenyl β-D Glucopyranoside effect on post-thaw sperm motion and viability traits of Murrah buffalo bulls 🧊💉
  • Rajvinder Grover, Narinder Singh, Shahbaz Singh Dhindsa, Prahlad Singh, VS Malik (2022) – Effect of propofol vs ketofol on cardiorespiratory functions during ovariohysterectomy in healthy dogs 🐕🩺
  • Gulia N, Honparkhe M, Bisla A, Singh AK and Singh P (2022) – Intrauterine proteolytic enzymes therapy hastens expulsion of fetal membranes in dystocia affected buffaloes 🐃💉
  • Prahlad Singh, Munish Kumar Bedi, Sumit Singhal, Ashwani Kumar Singh, Ajeet Kumar, Mrigank Honparkhe (2022) – Effect of graphene oxide as cryoprotectant on post-thaw sperm functional and kinetic parameters of cross bred (HF X Sahiwal) and Murrah buffalo bulls 🧊💡
  • Ankit Kumar Ahuja, Deepak Sharma, Arundeep Singh, Nitin Dev Singh and Prahlad Singh (2022) – Arterial thrombosis and fibrinoid necrosis-possible etiology behind hydroallantois in Bubalus bubalis (water buffalo) 🐃⚡
  • US Khinda, SS Dhindsa, M Honparkhe, VS Malik and Prahlad Singh (2021) – Relationship between Estrus expression and fertility in Sahiwal cattle following modified timed artificial insemination protocols 🐄🌾
  • A K Singh, U Singh, A Sharma, P Kaur and Prahlad Singh (2021) – Effect of flaxseed supplementation on metabolic profile and reproductive performance of prepubertal gilts 🐖🥇
  • SS Dhindsa, SS Sodhi, Bilawal Singh and Prahlad Singh (2021) – Constraints faced by small holder dairy farmers in Ludhiana district of Punjab 🐄💼

Conclusion:

Prahlad Singh is a highly qualified and experienced researcher with a distinguished career in Veterinary Science. His academic achievements, combined with over a decade of professional experience, make him an outstanding candidate for the Best Researcher Award. His commitment to advancing research in veterinary science, specifically in fertility, cryobiology, and animal husbandry, sets him apart as an eminent scientist.

His leadership in developing national and international collaborations and contributions to livestock health management underscore his value in the field. Further improvements can be made by expanding his collaborations into other areas of agriculture and increasing his outreach to a broader audience.

Based on these strengths, Prahlad Singh is not only suitable for the Best Researcher Award, but he also demonstrates the qualities of an innovative leader who continues to contribute significantly to veterinary and animal sciences.