Sedigheh Gharbi | Stem Cell Research | Best Researcher Award

Published on by Cell Biologist

Dr. Sedigheh Gharbi | Stem Cell Research | Best Researcher Award

Dr. Sedigheh Gharbi | Shahid Bahonar University of Kerman, Kerman, Iran | Iran

Assistant Prof. Dr. Sedigheh Gharbi is a dedicated Iranian biologist. She is currently an Assistant Professor at Shahid Bahonar University of Kerman, specializing in molecular biology with a strong focus on non-coding RNAs and their roles in cancer and cardiac regeneration. With over a decade of academic and research experience, Dr. Gharbi has contributed extensively to understanding microRNAs and long non-coding RNAs in disease mechanisms. She is recognized for her work on cardiomyocyte regeneration, cancer biology, and novel RNA regulatory networks. Dr. Gharbi has published numerous peer-reviewed articles, demonstrating her commitment to advancing biomedical research. Her research aims to translate molecular findings into potential therapeutic strategies, especially in oncology and regenerative medicine. She is also known for mentoring students and collaborating internationally to foster innovation in life sciences.

Publication Profile: 

Google Scholar

Education:

Dr. Sedigheh Gharbi completed her PhD in Molecular Biology at Tarbiat Modares University, Tehran. Her doctoral thesis focused on the microRNA expression profile alterations in serum and urine of sulfur mustard victims, under the supervision of Prof. Seyyed Javad Mowla. This work laid the foundation for her expertise in microRNAs and their diagnostic potential in toxicology and disease. Before her PhD, she earned a Master of Science degree from the University of Isfahan, where she conducted research on the mutational screening of the PIK3CA gene in breast cancer patients under Prof. Manoochehr Tavassoli. This early work sparked her interest in cancer genetics and molecular markers. Her education combined advanced molecular techniques with applied biomedical research, equipping her with the skills necessary for innovative studies in RNA biology and its implications in human diseases.

Experienc:

Since 2014, Dr. Gharbi has served as an Assistant Professor at Shahid Bahonar University of Kerman, where she lectures and leads research in molecular biology and cancer genetics. Her academic career is marked by active involvement in teaching, supervising graduate students, and securing research projects. She has a proven record in managing interdisciplinary studies focused on cardiomyocyte regeneration and RNA biology. Dr. Gharbi’s research experience spans molecular profiling of cancer biomarkers, non-coding RNA regulatory networks, and nanotechnology applications in drug delivery. She has collaborated with multiple research teams nationally and internationally, contributing to both fundamental science and translational medicine. Her role involves experimental design, bioinformatics analysis, and dissemination of findings through scientific publications and conferences. Dr. Gharbi’s experience in mentoring young scientists and publishing extensively positions her as a leader in her field.

Research Focus:

Dr. Gharbi’s primary research focus lies in the regulatory roles of non-coding RNAs—especially microRNAs (miRNAs) and long non-coding RNAs (lncRNAs)—in disease pathogenesis and therapy. She investigates cardiomyocyte regeneration by exploring how lncRNAs influence cell cycle progression, aiming to improve heart repair after injury. In oncology, her research centers on the regulatory structure of E-cadherin and the involvement of non-coding RNAs in cancer progression and management. Additionally, Dr. Gharbi is dedicated to identifying novel miRNAs and elucidating their functions in cellular processes like apoptosis and proliferation. Her work integrates molecular biology techniques with bioinformatics to uncover RNA-based biomarkers and therapeutic targets. The intersection of nanotechnology and RNA therapeutics is another emerging area in her studies, aiming to optimize cancer treatment delivery systems. Overall, her research contributes to understanding complex gene regulation mechanisms and developing RNA-based precision medicine strategies.

Publications Top Notes: 

  1. Mir-542 As A Potential and Promising Therapeutic Target For HPV-Positive Cervical Cancers

  2. CircPAN3/miR-221/PTEN Axis and Apoptosis in Myocardial Infarction: Quercetin’s Regulatory Effects

  3. Controlled cytotoxicity of Ag-GO nanocomposite biosynthesized using black peel pomegranate extract against MCF-7 cell line

  4. Characterization of the first microRNA in human CDH1 that affects cell cycle and apoptosis and indicates breast cancers progression

  5. Curcumin loaded on graphene nanosheets induced cell death in mammospheres from MCF-7 and primary breast tumor cells

  6. Bioinformatics Prediction of microRNAs Regulating Epithelial-to-Mesenchymal Transition in Cancer Cells

  7. Secondary toxic effect of graphene oxide and graphene quantum dots alters the expression of miR-21 and miR-29a in human cell lines

  8. Statins: Complex outcomes but increasingly helpful treatment options for patients

  9. Synthesis and characterization of d10 transition metal complexes in bulk and nano scales: DNA binding, molecular docking and anticancer activity against MCF-7 cell line

  10.  Quantification of circulating miR-517c-3p and miR-210-3p levels in preeclampsia

Conclusion:

In conclusion, Assistant Prof. Dr. Sedigheh Gharbi is highly suitable for the Best Researcher Award based on her consistent track record of innovative, impactful research and academic contributions. Her focus on molecular biology, especially the regulatory roles of non-coding RNAs in cancer and cardiac regeneration, addresses some of the most challenging issues in contemporary biomedical science. Her extensive publication record in reputable journals reflects the quality and significance of her work. While there are opportunities for further enhancing her international collaborations, funding portfolio, and translational efforts, her current achievements already mark her as a leading researcher with great potential for continued contributions. Awarding her the Best Researcher Award would recognize her scientific excellence and encourage further advancements in her promising research career.

 

Chunli Ma | Stem Cell Research | Best Researcher Award

Published on by Cell Biologist

Ms. Chunli Ma | Stem Cell Research | Best Researcher Award

Ms. Chunli Ma  , Shandong Provincial Hospital Affiliated to Shandong First Medical University , China

Chunli Ma is a Master’s student at Shandong Provincial Hospital Affiliated with Shandong First Medical University in China. With a strong background in Optometry and Vision Science, Ma has expanded into Ophthalmology for her graduate studies. She possesses a deep understanding of ocular disorders and the corresponding diagnostic and treatment protocols. She is passionate about cellular and molecular experimentation, specializing in animal models for scientific research. Her expertise extends to experimental techniques that offer innovative solutions for eye injury and healing. Chunli’s work aims to improve corneal repair, reduce scarring, and enhance treatment outcomes for ocular diseases through advanced therapeutic approaches, including stem cell therapy and specialized eye drops.

Publication Profile:

Orcid

Strengths for the Award:

Chunli Ma is a promising researcher with a strong foundation in both clinical ophthalmology and experimental techniques. Her academic background in Optometry and Vision Science, along with her specialized focus on Ophthalmology, positions her as an emerging leader in the field. Ma’s contributions to the understanding and treatment of corneal injuries, particularly her work on exosomes derived from adipose mesenchymal stem cells and antibacterial eyedrops, have significant therapeutic potential. The formulation of exosomes into eyedrops to aid in rapid corneal healing and prevent scarring, along with the development of multifunctional eyedrops for treating bacterial keratitis, showcases her innovative approach to solving complex clinical challenges. Her ability to translate laboratory research into potential clinical applications is commendable. Moreover, her publications in well-regarded journals and ongoing involvement in impactful research add to her eligibility for the Best Researcher Award.

Areas for Improvement:

While Chunli Ma’s work demonstrates great potential, there are areas where she could continue to develop. Expanding her research to a broader range of ocular conditions beyond corneal injury and keratitis could make her work even more influential across various ophthalmic fields. Additionally, seeking more collaborations with interdisciplinary teams, such as those focusing on the genetic and molecular mechanisms of ocular diseases, could provide deeper insights and enhance her ability to tackle more complex issues. Although she has made valuable contributions to scientific publications, continuing to increase the number and impact of her published papers, especially in top-tier journals, will further solidify her reputation in the scientific community. Gaining experience in patent applications and commercialization of her research could also help bridge the gap between laboratory findings and real-world clinical application.

Education:

Chunli Ma completed her undergraduate degree in Optometry and Vision Science, where she gained foundational knowledge in ocular health and vision correction. Building on this, she pursued a Master’s degree in Ophthalmology, which allowed her to specialize in clinical and experimental ophthalmic research. Her academic journey includes hands-on research in cell biology, molecular techniques, and experimental models to address common ocular disorders, particularly in corneal injury repair. Chunli’s academic training has not only refined her diagnostic skills but also equipped her with cutting-edge knowledge in treatment and therapeutic strategies. Her graduate work bridges practical clinical care with advanced research, focusing on cellular regeneration, stem cell treatments, and tissue healing in the eye. This robust academic background underpins her ongoing commitment to advancing ophthalmic medicine through innovative scientific inquiry and applied research in the field of corneal injury and wound healing.

Experience:

Chunli Ma’s academic journey has been bolstered by hands-on experience in both clinical ophthalmology and cellular research. Her work in experimental ophthalmology has focused on the use of adipose mesenchymal stem cells for corneal repair, creating new methodologies for promoting healing and reducing scarring. She has demonstrated expertise in animal model management and experimentation, gaining insights into complex biological processes affecting eye injuries. Ma has contributed to the development of novel treatments, including multifunctional eye drops for both bacterial keratitis and corneal trauma. Her research findings have important clinical implications, directly informing therapeutic strategies for ocular health. Additionally, Ma’s experience includes publishing scientific articles, with a growing portfolio in well-regarded journals. This combination of clinical knowledge, experimental research, and hands-on technique has allowed her to make valuable contributions to ophthalmic science, particularly in terms of innovative solutions for corneal injury and healing.

Research Focus:

Chunli Ma’s research focus is centered on the mechanistic modulation of corneal injury and wound healing. She investigates the potential of stem cell-derived exosomes in promoting the regeneration of corneal tissues, with a particular interest in their role in reducing scarring after trauma. Her work delves into advanced therapeutic applications, such as multifunctional eye drops containing composite antibacterial and healing properties for the treatment of Pseudomonas aeruginosa keratitis. By targeting the underlying molecular and cellular mechanisms of corneal repair, Ma aims to offer innovative solutions for treating corneal injuries and infections. Her research also explores the impact of wound size and location on the prognosis of penetrating ocular injuries, offering a more nuanced approach to patient care. Chunli’s focus on the development of cutting-edge materials and therapies for ophthalmic applications promises significant advances in clinical practice, particularly for patients with challenging corneal conditions.

Publications Top Notes:

  1. Exosomes derived from adipose mesenchymal stem cells promote corneal injury repair and inhibit the formation of scars by anti-apoptosis 📑🧬
  2. Wound size and location affect the prognosis of penetrating ocular injury 👁️‍🗨️🩹
  3. Potential role of ARG1 c.57G > A variant in Argininemia 🔬🧬

Conclusion:

Chunli Ma’s research reflects an excellent blend of clinical expertise and innovative scientific inquiry. Her work has already made notable contributions to improving the treatment of ocular injuries, particularly in corneal healing and bacterial keratitis. With a clear focus on translational research, she has demonstrated the potential for significant advancements in ophthalmic treatments. Given her ongoing dedication to advancing ophthalmology through novel therapeutic approaches, Chunli Ma is undoubtedly a strong candidate for the Best Researcher Award. With continued growth in her research, collaboration efforts, and scholarly output, she has the potential to make even greater strides in the field of ophthalmology and regenerative medicine.