Dr. Sedigheh Gharbi | Shahid Bahonar University of Kerman, Kerman, Iran | Iran
Assistant Prof. Dr. Sedigheh Gharbi is a dedicated Iranian biologist. She is currently an Assistant Professor at Shahid Bahonar University of Kerman, specializing in molecular biology with a strong focus on non-coding RNAs and their roles in cancer and cardiac regeneration. With over a decade of academic and research experience, Dr. Gharbi has contributed extensively to understanding microRNAs and long non-coding RNAs in disease mechanisms. She is recognized for her work on cardiomyocyte regeneration, cancer biology, and novel RNA regulatory networks. Dr. Gharbi has published numerous peer-reviewed articles, demonstrating her commitment to advancing biomedical research. Her research aims to translate molecular findings into potential therapeutic strategies, especially in oncology and regenerative medicine. She is also known for mentoring students and collaborating internationally to foster innovation in life sciences.
Publication Profile:
Education:
Dr. Sedigheh Gharbi completed her PhD in Molecular Biology at Tarbiat Modares University, Tehran. Her doctoral thesis focused on the microRNA expression profile alterations in serum and urine of sulfur mustard victims, under the supervision of Prof. Seyyed Javad Mowla. This work laid the foundation for her expertise in microRNAs and their diagnostic potential in toxicology and disease. Before her PhD, she earned a Master of Science degree from the University of Isfahan, where she conducted research on the mutational screening of the PIK3CA gene in breast cancer patients under Prof. Manoochehr Tavassoli. This early work sparked her interest in cancer genetics and molecular markers. Her education combined advanced molecular techniques with applied biomedical research, equipping her with the skills necessary for innovative studies in RNA biology and its implications in human diseases.
Experienc:
Since 2014, Dr. Gharbi has served as an Assistant Professor at Shahid Bahonar University of Kerman, where she lectures and leads research in molecular biology and cancer genetics. Her academic career is marked by active involvement in teaching, supervising graduate students, and securing research projects. She has a proven record in managing interdisciplinary studies focused on cardiomyocyte regeneration and RNA biology. Dr. Gharbi’s research experience spans molecular profiling of cancer biomarkers, non-coding RNA regulatory networks, and nanotechnology applications in drug delivery. She has collaborated with multiple research teams nationally and internationally, contributing to both fundamental science and translational medicine. Her role involves experimental design, bioinformatics analysis, and dissemination of findings through scientific publications and conferences. Dr. Gharbi’s experience in mentoring young scientists and publishing extensively positions her as a leader in her field.
Research Focus:
Dr. Gharbi’s primary research focus lies in the regulatory roles of non-coding RNAs—especially microRNAs (miRNAs) and long non-coding RNAs (lncRNAs)—in disease pathogenesis and therapy. She investigates cardiomyocyte regeneration by exploring how lncRNAs influence cell cycle progression, aiming to improve heart repair after injury. In oncology, her research centers on the regulatory structure of E-cadherin and the involvement of non-coding RNAs in cancer progression and management. Additionally, Dr. Gharbi is dedicated to identifying novel miRNAs and elucidating their functions in cellular processes like apoptosis and proliferation. Her work integrates molecular biology techniques with bioinformatics to uncover RNA-based biomarkers and therapeutic targets. The intersection of nanotechnology and RNA therapeutics is another emerging area in her studies, aiming to optimize cancer treatment delivery systems. Overall, her research contributes to understanding complex gene regulation mechanisms and developing RNA-based precision medicine strategies.
Publications Top Notes:
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Mir-542 As A Potential and Promising Therapeutic Target For HPV-Positive Cervical Cancers
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CircPAN3/miR-221/PTEN Axis and Apoptosis in Myocardial Infarction: Quercetin’s Regulatory Effects
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Controlled cytotoxicity of Ag-GO nanocomposite biosynthesized using black peel pomegranate extract against MCF-7 cell line
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Characterization of the first microRNA in human CDH1 that affects cell cycle and apoptosis and indicates breast cancers progression
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Curcumin loaded on graphene nanosheets induced cell death in mammospheres from MCF-7 and primary breast tumor cells
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Bioinformatics Prediction of microRNAs Regulating Epithelial-to-Mesenchymal Transition in Cancer Cells
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Secondary toxic effect of graphene oxide and graphene quantum dots alters the expression of miR-21 and miR-29a in human cell lines
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Statins: Complex outcomes but increasingly helpful treatment options for patients
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Synthesis and characterization of d10 transition metal complexes in bulk and nano scales: DNA binding, molecular docking and anticancer activity against MCF-7 cell line
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Quantification of circulating miR-517c-3p and miR-210-3p levels in preeclampsia
Conclusion:
In conclusion, Assistant Prof. Dr. Sedigheh Gharbi is highly suitable for the Best Researcher Award based on her consistent track record of innovative, impactful research and academic contributions. Her focus on molecular biology, especially the regulatory roles of non-coding RNAs in cancer and cardiac regeneration, addresses some of the most challenging issues in contemporary biomedical science. Her extensive publication record in reputable journals reflects the quality and significance of her work. While there are opportunities for further enhancing her international collaborations, funding portfolio, and translational efforts, her current achievements already mark her as a leading researcher with great potential for continued contributions. Awarding her the Best Researcher Award would recognize her scientific excellence and encourage further advancements in her promising research career.