Santosh Kumar | Cellular Senescence Aging | Best Researcher Award

Published on by Cell Biologist

Assist. Prof. Dr. Santosh Kumar | Cellular Senescence Aging | Best Researcher Award

Georgetown University | United States

Dr. Santosh Kumar is a cancer biologist with extensive experience in cellular and molecular oncology, particularly in understanding the molecular mechanisms that regulate cancer progression, therapy resistance, and tumor heterogeneity. His work integrates advanced 2D and 3D cell-culture systems, immunophenotyping, flow cytometry, and high-resolution microscopy to dissect tumor cell behavior in physiologically relevant contexts. With strong expertise in RNA–protein interaction assays, including EMSA and complementary biochemical approaches, he investigates post-transcriptional regulation and molecular signaling pathways that influence cancer stem cell dynamics and immune-related phenotypes within tumors. Dr. Kumar’s research has also focused on identifying biomarkers associated with tumor aggressiveness and exploring how stress responses and radiation exposure influence cancer cell survival and transformation. His postdoctoral and faculty-level research contributions have advanced the understanding of stem-like tumor cell populations and their role in therapeutic resistance. Through collaborative translational studies, he has contributed to projects aimed at improving diagnostic strategies and developing targeted interventions in oncology. Recognized through awards such as the Radiation Research Society’s Early Career Investigator Award and the NSBRI Post-Doctoral Fellow Presentation Award, Dr. Kumar continues to contribute to innovative cancer research with an emphasis on molecular mechanisms, immunophenotyping, and stem-cell-driven tumor biology.

Profile: Orcid

Featured Publications:

  • Kumar, S., Kumar, K., Angdisen, J., Suman, S., Kallakury, B. V. S., & Fornace, A. J., Jr. (2025). cGAS/STING pathway mediates accelerated intestinal cell senescence and SASP after GCR exposure in mice. Cells, 14, 1767.

  • Kumar, K., Moon, B. H., Kumar, S., Angdisen, J., Kallakury, B. V. S., Fornace, A. J., & Suman, S. (2025). Senolytic agent ABT-263 mitigates low- and high-LET radiation-induced gastrointestinal cancer development in Apc<sup>1638N/+ </sup> mice. Aging, 16.

  • Kumar, S., Suman, S., Angdisen, J., Moon, B. H., Kallakury, B. V. S., Datta, K., & Fornace, A. J., Jr. (2024). Effects of high-linear-energy-transfer heavy ion radiation on intestinal stem cells: Implications for gut health and tumorigenesis. Cancers, 16(19), 3392.

  • Kwiatkowski, E., Suman, S., Kallakury, B. V. S., Datta, K., Fornace, A. J., Jr., & Kumar, S. (2023). Expression of stem cell markers in high-LET space radiation-induced intestinal tumors in Apc<sup>1638N/+ </sup> mouse intestine. Cancers, 15(17).

  • Kumar, K., Kumar, S., Datta, K., Fornace, A. J., Jr., & Suman, S. (2023). High-LET-radiation-induced persistent DNA damage response signaling and gastrointestinal cancer development. Current Oncology, 30(6), 5497–5514.

  • Kumar, S., Suman, S., Moon, B. H., Fornace, A. J., Jr., & Datta, K. (2023). Low-dose radiation upregulates Ras/p38 and NADPH oxidase in mouse colon two months after exposure. Molecular Biology Reports, 50(3), 2067–2076.

  • Suman, S., Kumar, S., Kallakury, B. V. S., Moon, B. H., Angdisen, J., Datta, K., & Fornace, A. J., Jr. (2022). Predominant contribution of the dose received from constituent heavy-ions in the induction of gastrointestinal tumorigenesis after simulated space radiation exposure. Radiation and Environmental Biophysics, 61(4), 631–637.

 

Ali Esmaeili | Cellular Senescence Aging | Best Researcher Award

Published on by Cell Biologist

Assoc. Prof. Dr. Ali Esmaeili | Cellular Senescence Aging | Best Researcher Award

Allameh Tabatabai | Iraq

Associate Professor Dr. Ali Esmaeili’s research primarily focuses on the psychological and cognitive dimensions of sports science and human movement behavior. His extensive body of work explores how emotional regulation, motivation, and social skills influence executive functions and overall well-being among students and athletes. Esmaeili has investigated the mediating role of emotional regulation in the relationship between social skills and executive functioning, as well as the cognitive benefits of game-based sports exercises for late learners. His studies also examine how sports participation enhances social identity and well-being, particularly among female students. Beyond educational contexts, Esmaeili’s research extends to clinical and developmental psychology, addressing topics such as attention-deficit/hyperactivity disorder, separation anxiety, and emotion regulation in families with children with autism. He has further contributed to understanding attentional bias modification, forgiveness therapy, and hypnosis as psychological interventions for improved mental health and performance. His publications span multiple interdisciplinary journals, bridging physical education, cognitive psychology, and behavioral sciences, highlighting his commitment to integrating psychological frameworks into sports and movement studies. Collectively, Esmaeili’s research advances knowledge in sport psychology, emphasizing emotional and cognitive development through structured physical activity and psychological skill training.

 Profile: Scopus

Featured Publications:

Esmaeili, A. (2025). Exploring factors influencing sustainable behaviors in undergraduate students’ sports participation through model development and validation. Scientific Reports.

Esmaeili, A. (2024). The mediating role of emotional regulation skills in the relationship between social skills with executive functions of students. Modern Psychological Research.

Esmaeili, A. (2024). Effect of game-based sports exercises on high-level cognitive processes of late learners. Cognition Behavior Learning Journal.

Esmaeili, A. (2024). The role of motivating sports participation in the social well-being and social identity of female students of the first secondary school of knowledge in rural Jajarm City. Psychology of Development (Royeshe-Ravanshenasi).