Pawanpreet Singh | Pharmacy | Best Researcher Award

Assoc. Prof. Dr. Pawanpreet Singh | Pharmacy | Best Researcher Award

Assoc. Prof. Dr. Pawanpreet Singh , RIMT University , India

Dr. Pawanpreet Singh is an accomplished academic and researcher in the field of Pharmaceutical and Medicinal Chemistry. He currently serves as an Associate Professor at RIMT University, Punjab, with a focus on Crystal Engineering, Polymorphism, Co-crystallization, and Pharmaceutical Solids Modification. With over a decade of experience in teaching and research, he has contributed to various scientific advancements, particularly in pharmaceutical solid dosage forms. Dr. Singh has worked as a Postdoctoral Fellow at Dr. Reddy’s Laboratories and as a UGC-Research Fellow at Panjab University. He has also presented at international conferences and has been a part of significant research projects in pharmaceutical sciences. His expertise in computational modelling, crystallography, and formulation R&D is highly regarded, and he is a dedicated educator and mentor in the field.

Publication Profile:

Scopus

Strengths for the Award:

  1. Extensive Academic Background: Dr. Pawanpreet Singh has an impressive academic record, holding a Ph.D. in Pharmaceutical Chemistry and M.Pharm. with distinction. His research work is extensive and covers key areas in pharmaceutical and medicinal chemistry, including crystal engineering, polymorphism, and co-crystallization.
  2. Diverse Research Experience: Dr. Singh has significant research experience across various esteemed institutions, including RIMT University, Panjab University, and I.K. Gujral Punjab Technical University. His research areas, including pharmaceutical solids modification and clinical research, demonstrate his broad expertise.
  3. Postdoctoral and Industry Experience: His postdoctoral work at Dr. Reddy’s Laboratories, focusing on formulation R&D and quality improvement programs, shows practical industry application and hands-on experience in improving pharmaceutical processes, which further strengthens his credentials.
  4. Innovation and Publications: Dr. Singh has contributed several high-impact research papers in reputable journals, many of which are focused on crystal engineering and pharmaceutical development. His work on polymorph prediction and crystal structure determination has the potential to significantly impact drug design and development.
  5. Awards and Recognition: His consistent achievements, including an international travel award and recognition for his poster presentations at prestigious global conferences, highlight his reputation in the research community.
  6. Patents and Book Publications: Dr. Singh has been granted a patent for “Novel cocrystals of aceclofenac with improved bioavailability,” which showcases his innovation and contribution to pharmaceutical sciences. He has also authored books on medicinal chemistry and drug development.
  7. Hands-On Skills and Workshops: His active participation in various hands-on workshops, such as those on X-ray diffraction, chromatography, and crystallography, reflects his continuous effort to upgrade his technical skills.
  8. Leadership and Contribution to Academic Development: Dr. Singh’s role as a faculty member, his leadership as a class representative, and his involvement in various academic events demonstrate his leadership skills and commitment to educational advancement.

Areas for Improvement:

  1. Broader Interdisciplinary Collaboration: While Dr. Singh’s expertise in pharmaceutical chemistry is remarkable, expanding his research into more interdisciplinary domains, such as nanotechnology, biotechnology, and personalized medicine, could open new frontiers in his research career. Collaborating with experts from other fields could enhance the scope and impact of his work.
  2. Increased Research Visibility: Although Dr. Singh has made substantial contributions through publications and presentations, he could further enhance the visibility of his work by focusing on publishing in higher-impact journals or in interdisciplinary fields, where his work could influence broader scientific communities.
  3. Mentorship and Supervision: Given his considerable academic background, taking a more active role in mentoring Ph.D. and postdoctoral researchers could further contribute to the academic and research community. Increased focus on guiding future researchers would build a legacy of innovation and research excellence.
  4. Expanding International Collaborations: Although Dr. Singh has attended international conferences and presented posters globally, strengthening long-term international research collaborations could lead to more groundbreaking and globally impactful research projects.

Education:

Dr. Pawanpreet Singh completed his PhD in Pharmaceutical Sciences from the University Institute of Pharmaceutical Sciences, Panjab University, in 2018, under the supervision of Prof. Renu Chadha. His doctoral research focused on Crystal Engineering and Protein Binding Studies for antibacterial agents. Prior to this, he earned his Master’s in Pharmacy (M.Pharm) from G.H.G Khalsa College of Pharmacy in 2010, specializing in Pharmaceutical Chemistry with distinction. His undergraduate studies (B.Pharm) were completed at the same institution, where he achieved a first division. Dr. Singh also completed his secondary education at SCD Government College for Boys, Ludhiana, securing top positions. His strong academic foundation is further supported by certifications in specialized areas such as FTIR, HPLC, and X-ray diffraction, contributing to his expertise in medicinal chemistry and pharmaceutical research.

Experience:

Dr. Pawanpreet Singh has a rich academic and industrial experience spanning over a decade. He currently serves as an Associate Professor at RIMT University, Punjab, since February 2023, focusing on Pharmaceutical and Medicinal Chemistry. Prior to this role, he was an Assistant Professor at RIMT University, College of Pharmacy (September 2022 – February 2023) and at I.K. Gujral Punjab Technical University (November 2020 – June 2022). Dr. Singh has significant industrial exposure as a Postdoctoral Fellow at Dr. Reddy’s Laboratories (2017-2020), where he worked on Formulation R&D, technology transfer, and quality improvement. His research contributions are further backed by his work as a UGC-Research Fellow at Panjab University (2012-2017), under the guidance of Prof. Renu Chadha. With expertise in crystallography, formulation science, and computational modelling, he has developed several pharmaceutical products and processes, enhancing his academic and practical approach in research and teaching.

Awards and Honors:

Dr. Pawanpreet Singh has received numerous awards and honors throughout his career. He was awarded the prestigious UGC-Research Fellowship in Science for Meritorious Students (RFSMS) in 2012 for his outstanding academic performance. Dr. Singh also received the International Travel Award from the Department of Biotechnology, Government of India, to attend the ASM Microbe 2016 conference in Boston, USA. He won the First Prize in a poster presentation at the 10th National Conference on Thermodynamics of Pharmaceutical, Chemical, and Biological Systems in 2015. Additionally, he was recognized for his leadership as the Class Representative of PhD scholars at UIPS, Panjab University (2015-16). Dr. Singh’s research excellence is highlighted by his numerous publications in high-impact journals, and his contribution to the scientific community through his innovative work in pharmaceutical research. His achievements further underline his dedication to advancing pharmaceutical sciences and education.

Research Focus:

Dr. Pawanpreet Singh’s research interests are centered around Pharmaceutical and Medicinal Chemistry, with a particular focus on crystal engineering, polymorphism, and co-crystallization. His work aims to improve the physicochemical properties of pharmaceutical solid dosage forms, including their solubility, bioavailability, and stability. Dr. Singh has extensive experience in the preparation, characterization, and biological evaluation of various pharmaceutical solids, including polymorphs, co-crystals, and eutectics. His research integrates experimental and computational techniques, utilizing tools like CASTEP, Crystal Solve, and molecular docking to predict and characterize crystal structures. He has worked extensively on pharmaceutical polymorph screening and the design of solid forms with enhanced performance. Additionally, Dr. Singh is involved in formulating strategies for drug delivery and developing new methodologies for enhancing the stability and effectiveness of pharmaceutical compounds. His contributions to pharmaceutical solids modification have the potential to lead to more effective treatments with improved pharmacological properties.

Publications Top Notes:

  1. Structural and biopharmaceutical evaluation of newly synthesized norfloxacin co-crystals using crystal engineering approach, Journal of Molecular Structure, 2023 🧑‍🔬💊
  2. Depicting polymorphism in eutectic mixtures, DOI: 10.21203/rs.3.rs-1708945/v1 🔬📑
  3. A new polymorph of ciprofloxacin saccharinate: Structural characterization and pharmaceutical profile, Journal of Pharmaceutical and Biomedical Analysis, 2017 💊🔍
  4. Crystal structure prediction in the context of pharmaceutical polymorph screening and putative polymorphs of ciprofloxacin, International Journal of Pharmacy and Pharmaceutical Sciences, 2017 🔬💊
  5. Ciprofloxacin Hippurate Salt: Crystallization Tactics, Structural Aspects, and Biopharmaceutical Performance, Crystal Growth & Design, 2016 💊🧪
  6. Report on the Sixth Blind Test of Organic Crystal-Structure Prediction Methods, Acta Crystallographica Section B, 2016 🧑‍🔬📑
  7. New conformational polymorph of Hydrochlorothiazide with improved solubility, Pharmaceutical Development and Technology, 2015 💧💊
  8. Molecular Docking: A challenged and effectual approach, The Pharmacos, 2014 💻🔬
  9. Synthesis and thin layer chromatography of some new D-homo azasteroidal compounds, International Journal of Current Research and Review, 2011 🔬📄

Conclusion:

Dr. Pawanpreet Singh is highly deserving of the Best Researcher Award due to his deep expertise in pharmaceutical sciences, particularly in crystal engineering, polymorphism, and solid dosage form modification. His academic accomplishments, industrial experience, and significant contributions through research papers and patents make him an exemplary candidate. With continued interdisciplinary collaboration and greater international research visibility, Dr. Singh has the potential to further elevate his impact in the field. His track record of innovative research, mentorship, and leadership in academic settings highlights his commitment to advancing pharmaceutical sciences.

 

 

Arvind Singh Negi | Medicinal chemistry | Outstanding Scientist Award

Dr. Arvind Singh Negi | Medicinal chemistry | Outstanding Scientist Award

Dr. Arvind Singh Negi  , csir-cimap , India

Dr. Arvind Singh Negi, born on January 1, 1970, is a prominent scientist in the field of medicinal chemistry, currently serving as Chief Scientist and Head of the Phytochemistry Division at CSIR-Central Institute of Medicinal and Aromatic Plants, Lucknow, India. With a distinguished academic background and over three decades of experience, he specializes in natural product chemistry and the development of cancer chemotherapeutics. Dr. Negi has published extensively, contributing significantly to the understanding of plant-based medicinal compounds. His work has garnered numerous accolades, reflecting his commitment to advancing science in medicinal chemistry and natural products.

Publication Profile

Google Scholar

Strengths for the Award

Dr. Arvind Singh Negi possesses a robust academic background and extensive experience in medicinal chemistry, particularly in the development of cancer therapeutics from natural products. His impressive publication record, with over 106 research papers and significant citations, showcases his impact on the field. His leadership as Chief Scientist at CSIR-CIMAP reflects his ability to drive innovative research initiatives. Additionally, his multiple prestigious awards and fellowships, including recognition from the Royal Society of Chemistry and the National Academy of Sciences, underscore his scientific contributions and collaborations on a global scale.

Areas for Improvement

While Dr. Negi’s research achievements are commendable, expanding his outreach to interdisciplinary collaborations could enhance the applicability of his findings. Increasing engagement in public awareness and education on the significance of his research in medicinal chemistry could also strengthen his influence beyond academic circles. Further diversification of research themes might attract funding and foster novel explorations in related areas.

Education 

Dr. Negi completed his B.Sc. in Physics, Chemistry, and Mathematics from Lucknow Christian Degree College, University of Lucknow, in 1989. He excelled academically, earning his M.Sc. in Chemistry with First Rank from the same university in 1991. He further pursued a Ph.D. in Medicinal Chemistry at CSIR-Central Drug Research Institute, obtaining his degree in 1999. His educational journey includes significant research experiences, starting as a Scientist at ICAR-Indian Grassland and Fodder Research Institute in 1995. Dr. Negi has continuously advanced his knowledge and expertise through various fellowships, including prestigious opportunities at renowned international institutions, shaping his specialization in organic and natural product chemistry.

Experience 

Dr. Arvind Singh Negi boasts over 25 years of research experience in the field of medicinal chemistry. He began his career as a Scientist at ICAR-Indian Grassland and Fodder Research Institute in 1995, moving on to join CSIR-CIMAP in 2000. Over the years, he has progressed through various ranks, becoming a Chief Scientist in 2018. His extensive experience encompasses research and development of natural product-based pharmaceuticals, focusing on cancer therapeutics and organic synthesis. Dr. Negi has also supervised multiple Ph.D. theses and collaborated with national and international researchers, contributing to over 100 research publications. His leadership in the Phytochemistry Division has fostered innovative research projects, enhancing the institute’s reputation in medicinal plant research.

Awards and Honors 

Dr. Negi’s exemplary contributions to science have been recognized through numerous awards and honors. He was awarded the CSIR-JRF and Lectureship in 1991, followed by the ICAR Assistant Professorship in 1994. His research has earned him the Bioorganic & Medicinal Chemistry Most Cited Paper Award three times (2007, 2008, 2010) from Elsevier Press. He has received prestigious fellowships, including the ICS-UNIDO Fellowship in Italy (2008) and the Raman Research Fellowship in the USA (2010). Dr. Negi became a member of the National Academy of Sciences (NASI) in 2013 and was later invited to the Royal Society of Chemistry, achieving Fellow status in 2022. His recognition underscores his significant impact on medicinal chemistry and natural product research.

Research Focus 

Dr. Arvind Singh Negi specializes in medicinal chemistry, with a primary focus on the development of cancer chemotherapeutics. His current research involves designing target-specific molecules to modulate microtubule dynamics, a crucial aspect of cancer treatment. By harnessing the therapeutic potential of natural products, he investigates plant-based compounds that exhibit anticancer properties. His work encompasses extensive studies on the chemical and biological profiles of medicinal plants, contributing to the discovery of novel anticancer agents. Dr. Negi’s innovative approaches aim to bridge the gap between traditional knowledge and modern scientific methodologies, making significant strides in the field of phytochemistry. His research not only enhances our understanding of cancer therapeutics but also promotes the exploration of sustainable and effective treatments derived from nature.

Publication Top Notes

  1. Plant-based anticancer molecules: A chemical and biological profile of some important leads 🌱
  2. Antimicrobial potential of Glycyrrhiza glabra roots 🌿
  3. Recent advances in plant hepatoprotectives: a chemical and biological profile of some important leads 🌿
  4. Current status on development of steroids as anticancer agents 💊
  5. Antifungal activity of Glycyrrhiza glabra extracts and its active constituent glabridin 🌿
  6. Gallic acid-based indanone derivatives as anticancer agents 🌿
  7. Synergistic anticandidal activity of pure polyphenol curcumin I in combination with azoles and polyenes generates reactive oxygen species leading to apoptosis 🌿
  8. Natural antitubulin agents: Importance of 3, 4, 5-trimethoxyphenyl fragment 🌱
  9. Synthesis of chalcone derivatives on steroidal framework and their anticancer activities 💊
  10. Synthesis of 1-(3′,4′,5′-trimethoxy) phenyl naphtho[2,1b]furan as a novel anticancer agent 🌱
  11. Plant isoquinoline alkaloids: Advances in the chemistry and biology of berberine 🌱
  12. An insight into medicinal chemistry of anticancer quinoxalines 💊
  13. Antitubercular potential of some semisynthetic analogues of phytol 🌱
  14. Defective in cuticular ridges (DCR) of Arabidopsis thaliana, a gene associated with surface cutin formation, encodes a soluble diacylglycerol acyltransferase 🌱
  15. Nutritive evaluation of some nitrogen and non-nitrogen fixing multipurpose tree species 🌳
  16. Antiproliferative and antioxidant activities of Juglans regia fruit extracts 🌰
  17. Synthesis of pharmacologically important naphthoquinones and anticancer activity of 2-benzyllawsone through DNA topoisomerase-II inhibition 💊
  18. A bioactive labdane diterpenoid from Curcuma amada and its semisynthetic analogues as antitubercular agents 🌿
  19. Anticancer activity and toxicity profiles of 2-benzylidene indanone lead molecule 💊
  20. A promising anticancer and antimalarial component from the leaves of Bidens pilosa 🌿

Conclusion

Dr. Arvind Singh Negi is an exemplary candidate for the Outstanding Scientist Award. His pioneering work in medicinal chemistry, along with his dedication to advancing cancer therapeutics through innovative research, positions him as a leader in the field. With strategic enhancements in collaboration and outreach, his impact could extend even further, benefiting both scientific communities and public health.