Huiying Fan | Host-Pathogen Interactions | Best Researcher Award

Dr. Huiying Fan | Host-Pathogen Interactions | Best Researcher Award

Dr. Huiying Fan , College of Veterinary Medicine, South China Agricultural University , China

Dr. Huiying Fan is a distinguished professor and doctoral supervisor at the College of Veterinary Medicine, South China Agricultural University, specializing in veterinary virology and immunology. As a core member of the Key Laboratory for Veterinary Vaccine Development, his expertise includes creating genetically engineered vaccines for animal viruses. Dr. Fan has published over 40 research papers in leading journals, including Journal of Virology and Emerging Microbes & Infections, and holds 11 invention patents. His career has been marked by significant contributions to animal virus research and vaccine development, with extensive involvement in national research programs. He has been recognized with several provincial and ministerial-level awards and is actively involved in scientific development and industry collaboration in China.

Publication Profile:

Scopus

Strengths for the Award:

Dr. Huiying Fan has demonstrated exceptional contributions to the field of veterinary virology and immunology, particularly in the development of vaccines for animal viruses. He is a recognized leader in the creation of genetically engineered vaccines, with over 40 SCI papers published in high-impact journals such as Journal of Virology, Emerging Microbes & Infection, and Vaccines. His involvement in groundbreaking research on the pathogenic mechanisms of viruses like avian influenza, porcine epidemic diarrhea, and African swine fever underscores his expertise. Furthermore, Dr. Fan has been granted 11 invention patents and is an influential figure in national research programs, such as the National Key Research and Development Program. His leadership as a professor and mentor, coupled with his ongoing innovations in virus detection and vaccine development, showcases his remarkable impact in the field.

Areas for Improvement:

While Dr. Fan’s scientific research has been groundbreaking, expanding his focus on broader global collaborations could enhance the scope of his work. In particular, his work could benefit from incorporating more interdisciplinary approaches, combining cutting-edge technologies such as artificial intelligence or big data analytics, which are becoming increasingly crucial in disease surveillance and vaccine development. Moreover, his research could further address the application of his vaccine technologies in low-resource settings, to maximize global health impact. Engaging more actively in science communication could also help translate his findings into policies or programs that benefit larger populations, both within China and internationally.

Education:

Dr. Fan completed his Ph.D. in Preventive Veterinary Medicine at the College of Veterinary Medicine, Huazhong Agricultural University, in June 2007. During his doctoral research, he focused on the study of veterinary diseases and virus-host interactions, laying a strong foundation for his future work in vaccine development. His commitment to advancing veterinary science continued through postdoctoral training, followed by his establishment as a professor at South China Agricultural University. His education reflects his dedication to merging academic research with practical applications for the improvement of animal health and disease prevention.

Experience:

Dr. Fan’s career began in 2007 as a professor at South China Agricultural University, where he became a leading figure in veterinary medicine. He has also contributed significantly to international research, evidenced by his six-month research visit to City University of Hong Kong in 2016. As a core member of several high-impact research initiatives, including the National Key Research and Development Program, he has played a vital role in advancing veterinary virology and vaccine development. Dr. Fan’s extensive expertise has led to collaborations across national projects and scientific endeavors, particularly in the realm of infectious diseases and immune responses in animals.

Awards and Honors:

Dr. Fan has received multiple prestigious awards throughout his career, including 8 provincial and ministerial-level honors. Notably, he was named a “Pearl River Science and Technology Star” in Guangzhou and recognized as a “Science and Technology Commissioner” by the People’s Government of Guangdong Province. His contributions to veterinary science have garnered recognition both within China and internationally, highlighting his commitment to scientific excellence and industry collaboration. These accolades underscore his leadership in veterinary vaccine research and his influence on public health initiatives concerning animal diseases.

Research Focus:

Dr. Fan’s primary research interests lie in the molecular design of genetically engineered vaccines for animal viruses, including those affecting poultry and swine. His studies explore the immune mechanisms and pathogenesis of viruses such as avian influenza and porcine viral diarrhea. In addition to his work on vaccine development, he investigates the use of innovative techniques, including CRISPR/Cas12a and proteomics, to better understand virus-host interactions and to improve diagnostic and therapeutic strategies for animal diseases. His focus on veterinary virology aims to enhance both animal and public health outcomes.

Publication Top Notes:

  1. “A single immunization with H5N1 virus-like particle vaccine protects chickens against divergent H5N1 influenza viruses” 🐔🦠
  2. “Influenza H7N9 Virus Hemagglutinin with T169A Mutation Possesses Enhanced Thermostability” 🦠❄️
  3. “Immune Escape Mechanism and Vaccine Research Progress of African Swine Fever Virus” 🐖🦠
  4. “Supplementation of H7N9 Virus-Like Particle Vaccine With Recombinant Epitope Antigen Confers Full Protection” 🦠💉
  5. “PEDV infection affects the expression of polyamine-related genes inhibiting viral proliferation” 🐖🧬
  6. “Proteome Analysis in PAM Cells Reveals That African Swine Fever Virus Can Regulate Intracellular Polyamines” 🧬🔬
  7. “CRISPR/Cas12a Technology Combined with Immunochromatographic Strips for Portable Detection of ASF Virus” 🧬🦠
  8. “Quantitative Proteomics Reveals Changes in Vero Cells in Response to Porcine Epidemic Diarrhea Virus” 🐖🔬
  9. “Coimmunization with recombinant epitope-expressing baculovirus enhances protective effects of H5N1 vaccine” 💉🦠
  10. “Either fadD1 or fadD2, Which Encode acyl-CoA Synthetase, Is Essential for the Survival of Haemophilus parasuis SC096” 🦠🔬
  11. “Two Glycosyltransferase Genes of Haemophilus parasuis SC096 Implicated in Lipooligosaccharide Biosynthesis” 🧬🦠
  12. “Recombinant baculovirus vaccine containing multiple M2e and adjuvant LT induces T cell-dependent protection against H5N1” 💉🦠
  13. “BacMam virus-based surface display of IBV S1 glycoprotein confers strong protection against virulent IBV challenge” 🐔🦠
  14. “Quantitative Proteomics by Amino Acid Labeling in Foot-and-Mouth Disease Virus-Infected Cells” 🐄🧬
  15. “Quantitative proteomics using SILAC reveals protein and pathway regulation in porcine circovirus type 2 infected PK-15 cells” 🐖🧬

Conclusion:

Dr. Huiying Fan is undoubtedly a strong contender for the Research for Best Researcher Award, given his outstanding contributions to animal virus research, innovative vaccine design, and leadership in national research initiatives. His extensive publication record, patent portfolio, and recognition through prestigious awards highlight his scientific excellence. Although expanding his collaborative network and exploring interdisciplinary methodologies could elevate his impact further, Dr. Fan’s work has already had a profound effect on veterinary medicine and public health, making him a well-deserved nominee for this award.