Yavuz Tekelioğlu | Cancer Cell Biology | Best Academic Researcher Award

Published on by Cell Biologist

Prof. Dr. Yavuz Tekelioğlu | Cancer Cell Biology | Best Academic Researcher Award

Prof. Dr. Yavuz Tekelioğlu | Karadeniz Technical University | Turkey

Prof. Dr. Yavuz Tekelioğlu is a distinguished professor at Karadeniz Technical University’s Faculty of Medicine, specializing in histology, embryology, and toxicology. He has built a prolific academic career focused on cellular and tissue analysis using advanced methods like flow cytometry. Since beginning as a research assistant, he has steadily advanced through academic ranks, culminating in a full professorship. He has supervised numerous theses, contributing significantly to training future scientists. His research emphasizes the protective effects of antioxidants and stem cell therapies on tissue toxicity, with over 100 peer-reviewed publications. Active in professional societies, he also provides comprehensive educational instruction in medicine and dentistry. Prof. Tekelioğlu is committed to advancing biomedical research, particularly in reproductive and hepatic toxicology, through innovative experimental approaches.

Publication Profile:

Scopus

Education:

Prof. Dr. Yavuz Tekelioğlu completed his higher education at Karadeniz Technical University, where he earned his PhD after serving as a research assistant. His academic foundation is firmly rooted in medical sciences, with a focus on histology and embryology. During his doctoral studies, he developed expertise in experimental toxicology and cellular biology, particularly utilizing flow cytometry for immunophenotyping. His training includes specialized certifications in scientific research ethics, flow cytometry techniques, and institutional educational management. These credentials equip him to conduct rigorous, ethical research and provide effective academic leadership. Continuous participation in national and international workshops and symposiums reflects his commitment to staying current with cutting-edge methodologies and ethical standards in biomedical research.

Experience:

Starting as a research assistant, Prof. Tekelioğlu quickly advanced to PhD research assistant, assistant professor, associate professor, and finally full professor at Karadeniz Technical University. Over more than three decades, he has taught histology and embryology to medical, dental, and graduate students while supervising numerous theses on tissue toxicity and protective agents. He has led multiple TÜBİTAK and university-funded projects focusing on mesenchymal stem cells and toxicological evaluations using flow cytometry and histopathology. His academic service extends to practical flow cytometry training, contributing to capacity building in biomedical research. His administrative roles include coordinating research ethics training and educational management. He is a member of prominent scientific societies, contributing to Turkey’s scientific community. His career demonstrates dedication to both research and education.

Research Focus:

Prof. Dr. Tekelioğlu’s research primarily focuses on the histopathological and immunological effects of toxic agents on reproductive and hepatic tissues. His work extensively explores the protective roles of antioxidants like vitamin E, lycopene, beta-glucan, and Coenzyme Q10 against methotrexate-induced toxicity. Employing flow cytometry, histology, and biochemical assays, his studies provide mechanistic insights into cellular apoptosis, oxidative stress, and tissue regeneration. He investigates mesenchymal stem cells for their therapeutic potential in tissue repair and immunomodulation. His experimental models often include rats and mice, enabling controlled studies of drug-induced organ damage and protective interventions. By bridging toxicology with cellular analysis, his research contributes to safer clinical drug use and novel treatment strategies. Additionally, his recent work on ovarian and cardiac protection highlights translational relevance. His interdisciplinary approach combines toxicology, reproductive biology, and flow cytometry, establishing him as a leader in biomedical research.

Publication Top Notes: 

  • Coenzyme Q10 may protect ovarian tissue against methotrexate-induced gonadotoxicity: a biochemical, flow cytometric, and histopathological study

  • A Comparison of the Flow Cytometric Analysis Results of Benign and Malignant Serous Tumors of the Ovary

  • Should combined MTX and CoQ10 use be reconsidered in terms of steatosis? A biochemical, flow cytometry, histopathological experimental study

  • Histological and flow cytometric evaluation of astaxanthin’s effects against cyclophosphamide induced heart injury in rats

  •  Melamine exposure during the weaning period negatively affects ovarian reserve

Conclusion:

Prof. Dr. Yavuz Tekelioğlu is well-qualified and highly suitable for the Best Academic Researcher Award based on his extensive career, strong research leadership, significant scholarly contributions, and educational impact. His focused expertise on toxicology, histology, and cellular analysis is both relevant and impactful.

With strategic enhancements in international collaborations and visibility, he can further solidify his standing as a leading academic researcher. Nonetheless, his current achievements and dedication clearly merit recognition at this level.

Iwona Kwiecień | Cancer Cell Biology | Best Researcher Award

Published on by Cell Biologist

Assist. Prof. Dr. Iwona Kwiecień | Cancer Cell Biology | Best Researcher Award

Assist. Prof. Dr. Iwona Kwiecień , Military Institute of Medicine – National Research Institute , Poland

Iwona Kwiecień, PhD, is an expert in clinical immunology and laboratory medicine. With a strong academic background and extensive experience in medical research, she has dedicated her career to exploring immunological mechanisms in various diseases. She is currently working at the Military Institute of Medicine in Warsaw, where she serves as a lab specialist and lecturer. Dr. Kwiecień holds a PhD in Medical Science with a specialization in immunology from the Medical University of Warsaw. Her research focuses on the immune response in lung cancer, sarcoidosis, and other inflammatory diseases, employing advanced techniques such as multicolor flow cytometry. Her scientific contributions have been recognized globally, and she continues to shape the field of immunology through her research and teaching.

Publication Profile:

Scopus

Strengths for the Award:

Dr. Iwona Kwiecień possesses an impressive academic background and a consistent record of significant contributions to the field of immunology and medical research. With a Ph.D. in Medical Science and immunology, along with expertise in laboratory medicine, hematology, and flow cytometry, Dr. Kwiecień has shown remarkable skill in investigating the immune system’s role in lung cancer and other diseases. Her work on antigenic profiles in the lung cancer microenvironment, macrophage subpopulations in lung cancer, and immune responses in systemic inflammation highlights her strong research abilities. The 2024 habilitation diploma is a testament to her research excellence. Furthermore, Dr. Kwiecień has contributed to the publication of numerous peer-reviewed articles with significant citations and impact, indicating her strong presence in the scientific community.

Areas for Improvement:

While Dr. Kwiecień has demonstrated significant strength in immunological research, expanding her focus to include other cancer types or diseases beyond lung cancer may broaden the scope of her impact. Additionally, fostering greater international collaboration could further enhance the dissemination of her research globally.

Education:

Iwona Kwiecień earned her Master of Science in Laboratory Medicine from the Medical University of Warsaw in 2012. Later, she completed her PhD at the same university’s First Faculty of Medicine, specializing in immunology, with a thesis on regulatory mechanisms of the immune response, which she defended in 2017. She further pursued a specialization in Laboratory Medical Hematology at the Medical University of Silesia in Katowice, Poland, completing it in 2021. Dr. Kwiecień is also set to receive her habilitation diploma from the Military Institute of Medicine-National Research Institute in 2024, based on her scientific achievements in lung cancer immunology. Throughout her academic journey, she has developed expertise in clinical cytology, flow cytometry, and immunological assays, contributing significantly to the scientific community.

Experience:

Dr. Iwona Kwiecień has accumulated substantial experience in the field of laboratory medicine and immunology, working at several prestigious institutions. Since 2017, she has been a laboratory specialist and lecturer at the Military Institute of Medicine-National Research Institute in Warsaw, focusing on flow cytometry and hematology. Her role involves designing, performing, and analyzing complex experiments, as well as providing education and training to students. Prior to her current position, Dr. Kwiecień worked as a research coordinator assistant at BioVirtus Research Site and Clinical Research Group in Warsaw. Her academic career also includes time spent at the University Clinical Center of the Medical University of Warsaw, where she collaborated on various pathology and immunology projects. Dr. Kwiecień’s professional experience extends to overseeing numerous grants and research projects, including her work on macrophage subpopulations and lung cancer.

Awards and Honors:

Dr. Iwona Kwiecień has received several accolades in recognition of her outstanding contributions to science and research. Among her awards is the prestigious “Gold Laurel Graduate” medal for being the best graduate of Laboratory Medicine at the Medical University of Warsaw in 2013. She also received the 2nd award from the Polish Archives of Internal Medicine for her student research on macrophage subpopulations in sarcoidosis in 2014. Additionally, Dr. Kwiecień has been the recipient of numerous research grants, including the 2014-2015 Grant for Young Scientific Researcher from the Medical University of Warsaw. Her work on macrophage subpopulations in lung cancer earned her a statutory grant at the Military Institute of Medicine in 2018-2019. These awards reflect her exceptional research contributions and commitment to advancing the field of clinical immunology and laboratory medicine.

Research Focus:

Dr. Iwona Kwiecień’s research focus lies primarily in the immunology of lung cancer, sarcoidosis, and inflammatory diseases. Her studies have explored immune responses, particularly the role of macrophages, regulatory T cells, and other immune cell populations in disease progression. A key area of her research involves the use of multicolor flow cytometry to assess antigenic profiles of cells in cancer microenvironments. She has contributed to the understanding of how immune cells, such as T cells and macrophages, interact with tumor cells in the context of lung cancer and other inflammatory conditions. Dr. Kwiecień has also researched the impact of systemic inflammation on diseases like obstructive sleep apnea. Her work aims to uncover novel therapeutic targets and provide insights into the immune mechanisms driving various pathologies. Through her research, Dr. Kwiecień continues to contribute valuable knowledge to the fields of clinical immunology and hematology.

Publications Top Notes:

  1. Frequency and spontaneous cytotoxicity of natural killer cells in healthy children: preliminary results 🧬🧒
  2. Association between M1 and M2 macrophages in bronchoalveolar lavage fluid and tobacco smoking in patients with sarcoidosis 💨🫁
  3. Cytometric analysis of perforin expression in NK cells, CD8+, and CD4+ lymphocytes in children with autoimmune Hashimoto’s thyroiditis 👶🦠
  4. T, B, and NKT Cells in Systemic Inflammation in Obstructive Sleep Apnea 😴🩺
  5. Macrophage polarization in interstitial lung diseases 💔🫁
  6. D4+/CD25high/FoxP3+/CD127- regulatory T cells in bronchoalveolar lavage fluid of lung cancer patients 🫀💉
  7. Elevated regulatory T cells, surface and intracellular CTLA‐4 expression and interleukin‐17 in the lung cancer microenvironment in humans 🫀🧪
  8. Elevated Foxp3/CD8 ratio in lung adenocarcinoma metastatic lymph nodes resected by transcervical extended mediastinal lymphadenectomy 🔬💊
  9. Immunophenotype of t cells expressing programmed death-1 and cytotoxic T cell antigen-4 in early lung cancer: local vs. systemic immune response 🎗️🫁
  10. Fas-positive lymphocytes are associated with systemic inflammation in obstructive sleep Apnea syndrome 🛏️🔬

Conclusion:

Dr. Iwona Kwiecień is a highly capable researcher whose work has made substantial contributions to clinical immunology. Her ongoing focus on the immune responses in cancer offers significant potential for advancing cancer diagnostics and therapeutics. With a strong academic and research background, she is undoubtedly a strong candidate for the Best Researcher Award.