Yong-Soo Bae | Immunology Cellular Interactions | Best Researcher Award

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Prof. Dr. Yong-Soo Bae | Immunology Cellular Interactions | Best Researcher Award

Prof. Dr. Yong-Soo Bae | Sungkyunkwan University | South Korea

Dr. Yong-Soo Bae is a distinguished immunologist and professor at the Department of Biological Science, Sungkyunkwan University, Korea. He currently serves as the Director of the SRC Center for Immune Research on Non-lymphoid Organs (CIRNOS). With over three decades of academic, clinical, and industry experience, Dr. Bae is internationally recognized for his pioneering research in immunology, virology, and vaccine development. His multidisciplinary contributions span academia, biotech innovation (as CEO/CTO of JW Creagene Inc.), and scientific leadership, including organizing global conferences and serving as editor-in-chief and president in numerous societies. His work focuses on immune modulation, cancer immunotherapy, and mucosal vaccines, which has led to influential publications in prestigious journals like Nature Communications, Science Advances, and Advanced Materials. Dr. Bae’s career reflects a commitment to innovation, collaboration, and education, making him a strong candidate for the Best Researcher Award.

Publication Profile:

Scopus

✅ Strengths for the Award

  1. Pioneering Research Leadership
    Dr. Bae has led groundbreaking research in immunology, particularly in immune regulation of non-lymphoid organs, vaccine development, and cancer immunotherapy. His leadership of the Center for Immune Research on Non-lymphoid Organs (CIRNOS) demonstrates his national influence in immune research.

  2. Extensive Scientific Contributions
    With over 18 high-impact publications in the past 3–4 years alone, including in top-tier journals like Nature Communications, Molecular Therapy, Science Advances, and Advanced Materials, Dr. Bae continues to push the boundaries of translational immunology and personalized medicine.

  3. International & Interdisciplinary Experience
    His training at Harvard Medical School, his professorships across Korean institutions, and leadership at JW Creagene Inc. showcase both academic and industrial impact.

  4. Scientific Community Engagement
    Roles such as Editor-in-Chief, society president, and organizer of global conferences (e.g., DC2012) reflect his commitment to advancing scientific dialogue and collaboration.

  5. Mentorship and Institutional Development
    Dr. Bae has contributed significantly to capacity building in Korea’s biomedical research landscape, mentoring junior scientists and shaping departmental growth.

⚠️ Areas for Improvement:

  1. Global Collaboration Visibility
    While his work is highly impactful in Korea and Asia, more joint publications with global institutions (e.g., NIH, Oxford, Karolinska) could further enhance international research influence.

  2. Patent and Commercial Output Reporting
    As former CEO/CTO of JW Creagene, elaborating on patented innovations or therapeutic products brought to market would strengthen the case for translational impact.

  3. Formal Recognition or Awards
    Inclusion of formal honors (e.g., national science medals, international society awards) would help quantify his recognition outside Korea.

  4. Consistent Author Disambiguation
    In some publications, author names appear as “Y.S. Bae” or “Yong-soo Bae.” Consistent use of a standardized author name across indexing platforms would help centralize his citation metrics and scholarly footprint.

 

🎓 Education:

Dr. Yong-Soo Bae’s academic journey began with a Bachelor’s and Master’s degree in Microbiology from Seoul National University in 1981 and 1983, respectively. His foundational training in microbiology laid the groundwork for his research trajectory in infectious disease and immunology. He earned his Ph.D. in 1990 from the University of Calgary, Alberta, Canada, in the Virology Division of the Department of Microbiology and Infectious Diseases, Faculty of Medicine. His doctoral research was crucial in shaping his interest in host-pathogen interactions and immune regulation. Dr. Bae’s international education experience has enabled him to blend Western and Eastern biomedical research paradigms, contributing to his ability to lead collaborative global projects and initiatives in immunotherapy and vaccine innovation.

💼 Experience:

Dr. Yong-Soo Bae’s professional career spans academia, research, and biotech leadership. He completed a postdoctoral fellowship at Dana-Farber Cancer Institute, Harvard Medical School (1991–1993), which enriched his expertise in cancer immunology. He held professorial roles at Hannam University (1993–2003) before joining Sungkyunkwan University in 2004, where he later became Department Chair and Distinguished Professor. Dr. Bae also served as Director of CIRNOS (2017–2024) and led JW Creagene Inc. as CEO/CTO (1998–2015), bridging science and industry. His editorial and leadership roles include Editor-in-Chief of the Journal of Bacteriology and Virology, President of the Korean Society of Virology, and Vice President of the Korean Vaccine Society. His diverse roles demonstrate a unique blend of academic excellence, organizational leadership, and translational research expertise.

🔍 Research Focus:

Dr. Yong-Soo Bae’s research focuses on innate and adaptive immune regulation, tumor immunology, mucosal immunotherapy, and vaccine delivery. He investigates cellular interactions in the immune microenvironment, with particular attention to innate lymphoid cells (ILCs), neutrophils, and dendritic cells. His translational work includes novel vaccine platforms, epitranscriptomics, immune checkpoint modulation (e.g., CISH, PD-1), and cell therapy for diseases such as asthma, leukemia, and cancer. He also explores microbiome-immune crosstalk and inflammation-related organ damage (e.g., renal fibrosis, lung inflammation). His group has published extensively on m6A modifiers, microRNAs, and innovative delivery systems like gel-to-nanovaccines. His latest studies dive into immunometabolism and the interplay between immune cells and tissue repair, offering groundbreaking insights for future immunotherapies. Dr. Bae’s work is highly cited and remains at the forefront of immune system-based therapeutic innovation.

📚 Publications Top Notes:

  1. 📘 Therapeutic Potential of microRNA Against Th2-associated Immune Disorders – Current Topics in Medicinal Chemistry (2021)

  2. 💉 COVID-19 Vaccines and Oral-Mucosal Vector System as a Potential Vaccine Platform – Vaccines (2021)

  3. 🧬 Immunotherapeutic Potential of m6A-Modifiers and microRNAs in AML – Biomedicines (2021)

  4. 🎯 Epitranscriptomic Approach to Improve ICB Therapy by Targeting CISH – Cells (2021)

  5. 🧫 TFH-B-TRM Dysregulation and Anti-PD-1 Responses in EGFR-mutant Lung Cancer – Nature Communications (2021)

  6. 🧪 Adenoviral CD200R-Ig Enhances Antitumor Immunity via M2 Macrophage Inhibition – Molecular Therapy

  7. 🌫 Air Pollutant-induced Neutrophils Worsen Airway Inflammation – JACI (2021)

  8. 🦠 NCR+ILC3s and the Microbiome in Asthma Severity – Immune Network (2021)

  9. 📖 Advances in Personalized Therapy for AML by Targeting Intracellular Checkpoints – eBook Chapter (2021)

  10. 🧵 Siglec-F Neutrophils Drive Fibrosis in Renal Disease – JCI (2022)

🧾 Conclusion:

Dr. Yong-Soo Bae is an exceptional and highly deserving candidate for the Best Researcher Award. His contributions over four decades span foundational research, translational innovation, academic leadership, and scientific diplomacy. The depth of his scientific output, particularly in immunology, epigenetics, and vaccine development, is matched by his long-term commitment to mentoring, editorial work, and building research institutions in Korea.While enhancing his global recognition and expanding international collaborative outputs could further elevate his status, Dr. Bae’s consistent high-impact contributions, research leadership, and policy involvement clearly position him as a top-tier researcher in the life sciences.

Fani Pantouli | Immunology Cellular Interactions | Best Researcher Award

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Dr. Fani Pantouli | Immunology Cellular Interactions | Best Researcher Award

Dr. Fani Pantouli, Cleveland Clinic Florida Research and Innovation Center, United States

Dr. Fani Pantouli is a passionate and results-driven research scientist with deep expertise in neuroscience, pharmacology, immunology, and oncology. A USA permanent resident, she currently serves as a Postdoctoral Fellow at the Cleveland Clinic Florida Research and Innovation Center. Her work bridges cutting-edge vaccine development and cancer therapeutics, contributing significantly to preclinical and translational research. Dr. Pantouli’s scientific approach blends in vivo and in vitro techniques to uncover therapeutic pathways, particularly in head and neck cancer and viral immunology. Her interdisciplinary knowledge is reflected in a growing portfolio of peer-reviewed publications addressing pressing biomedical challenges, from COVID-19 immunity to neuropsychiatric disorders. She is known for her innovative methodologies, collaborative mindset, and unwavering dedication to advancing human health. Dr. Pantouli’s work is making a meaningful impact on personalized medicine and translational therapeutics, positioning her as a rising leader in biomedical research.

Publication Profile: 

Orcid

✅ Strengths for the Award:

  1. Multidisciplinary Expertise
    Dr. Pantouli integrates neuroscience, immunology, pharmacology, and oncology into her research, making her contributions uniquely cross-disciplinary and impactful.

  2. High-Impact Research in Vaccine Development
    Her postdoctoral work on COVID-19 and respiratory viruses, particularly her development of T-cell profiling and viral neutralization assays, directly informs global efforts in personalized vaccine design.

  3. Innovative Cancer Models
    She developed a novel in vivo murine model for head and neck squamous cell carcinoma, advancing drug screening for p53-related targets. This is vital in understanding and treating cancers with p53 mutations.

  4. Robust Publication Record
    Dr. Pantouli has authored or co-authored multiple peer-reviewed articles in reputable journals (e.g., Vaccines, Neuropsychopharmacology), with several under review in top-tier outlets like Science and Journal of Biological Psychiatry.

  5. Focus on Health Equity
    Her research into ethnic differences in immune response underscores a strong commitment to inclusive and equitable healthcare.

  6. Experience in Preclinical & Translational Research
    Her hands-on experience building disease models and testing therapeutic strategies bridges basic science and clinical application—core to translational medicine.

⚠️ Areas for Improvement:

  1. Independent Research Leadership
    While she has made significant contributions as a postdoctoral fellow, moving toward independent investigator roles (e.g., PI on grants) would strengthen her candidacy.

  2. Visibility and Recognition
    Increased presence in international symposia, keynote talks, or award recognitions would help boost her visibility within the scientific community.

  3. Mentorship and Community Involvement
    Involvement in mentoring junior researchers or leading educational outreach initiatives could further showcase her leadership potential.

🎓 Education:

Dr. Pantouli holds a Ph.D. in Neuropharmacology from the University of Surrey and St. George’s University of London, awarded between 2014 and 2017. Her doctoral studies explored neural mechanisms underpinning pharmacological and behavioral outcomes, laying a solid foundation for her current work in translational medicine. Prior to her Ph.D., she completed an MSc in Molecular Neuroscience from the University of Bristol in 2011, where she specialized in neurodevelopmental and degenerative disorders. Her undergraduate studies were completed at the University of Bedfordshire in 2010, where she earned a BSc (Hons) in Biomedical Science. Dr. Pantouli’s academic trajectory reflects a commitment to interdisciplinary learning and a focus on brain and immune system interactions. Her education combines rigorous training in molecular biology, pharmacology, and neuroscience, empowering her to address complex biomedical questions with a systems-level perspective.

🧪 Experience:

Dr. Pantouli is currently a Postdoctoral Fellow in Vaccine Development Research at the Cleveland Clinic Florida Research and Innovation Center (June 2023 – Present), where she investigates T cell immune responses and develops viral neutralization assays for respiratory viruses including SARS-CoV-2. Previously, she was a Postdoctoral Fellow in the Cancer Research Lab at the same institute (January 2022 – June 2023), where she created innovative murine models of head and neck cancer to evaluate therapeutic efficacy targeting mutant p53. Her research integrates advanced in vivo systems and immune profiling to enhance drug discovery and vaccine evaluation. With a decade-long track record across academia and clinical research centers, Dr. Pantouli has developed robust platforms for translational research, immunotherapeutics, and precision medicine. Her skills span experimental design, animal modeling, immunoassays, and bioanalysis, equipping her to tackle critical gaps in infectious disease and oncology treatment strategies.

🔬 Research Focus:

Dr. Pantouli’s research is centered on translational medicine, focusing on vaccine development, immunotherapy, and molecular pharmacology. Her current projects address immune modulation in viral infections, especially COVID-19, and the development of preclinical assays for vaccine and drug evaluation. She also leads research in oncology, particularly targeting p53 mutations in head and neck squamous cell carcinoma using in vivo models. Her earlier academic work examined the neural and behavioral effects of neuropeptides and receptor modulators in models of autism and Fragile X Syndrome, showing a consistent interest in neuroimmune interactions. She employs a multidisciplinary approach—blending pharmacological, molecular, and immunological tools—to explore how targeted therapies can be optimized for diverse populations. Her work is vital for advancing personalized medicine, especially for aging populations and ethnically diverse cohorts, where vaccine efficacy and immune response can differ significantly.

📚 Publications Top Notes:

  • 🧫 Ethnic differences in COVID-19 T cell immunity responses across variants from Wuhan to Omicron – Accepted in Vaccines

  • 🧠 Evaluation of SR-17018 and oxycodone in the conditioned place preference paradigm using peanut butter chip vehicle – In preparation, Neuropharmacology

  • 🧬 Generation of antigen-specific paired heavy-light chain antibody sequences using large language models – Submitted to Science

  • 💉 COVID-19 Vaccination Enhances the Immunogenicity of Seasonal Influenza Vaccination in the Elderly – Vaccines (2025)

  • 🧩 Tilted striatofugal balance and mGluR4 modulation in the Fmr1 mouse model of Fragile X Syndrome – Under review, Journal of Biological Psychiatry

  • 👃 Acute, chronic and conditioned effects of intranasal oxytocin in mu opioid receptor knockout mice: social context matters – Neuropsychopharmacology (2024)

🧾 Conclusion:

Dr. Fani Pantouli is a highly promising and impactful scientist whose research spans some of the most critical health challenges of our time—infectious diseases, cancer, and neurodevelopmental disorders. Her technical expertise, innovative model development, and deep understanding of immune and neural systems make her an excellent nominee for the Best Researcher Award.