Published on 18/09/202518/09/2025 by Cell Biologist Assoc. Prof. Dr. Alexander Tsankov | Cancer Cell Biology | Best Researcher Award Icahn School Of Medicine At Mount Sinai | United States Alexander Tsankov is a leading researcher in computational biology and cancer genomics, known for his contributions to single-cell and spatial transcriptomics. He holds dual bachelor’s degrees in Plan II Honors and Electrical and Computer Engineering from the University of Texas at Austin, and earned his M.S. and Ph.D. in Electrical Engineering and Computer Science from MIT. His research focuses on understanding the cellular and molecular mechanisms underlying cancer progression and tissue remodeling, with an emphasis on glioblastoma, lung adenocarcinoma, and colorectal cancer. Dr. Tsankov has published extensively in top-tier journals such as Nature, Nature Communications, Cancer Discovery, Nature Genetics, and Immunity. He has authored over 50 peer-reviewed publications, with an h-index of 36 and more than 15,000 citations according to Google Scholar. His work has earned him several prestigious honors, including the NIH NRSA postdoctoral fellowship and the NSF graduate fellowship. Dr. Tsankov frequently serves as a senior or corresponding author, highlighting his leadership in the field of computational oncology and single-cell genomics. Profile: Google Scholar Featured Publications: “Learning the cellular origins across cancers using single-cell chromatin landscapes” “Cellular and spatial atlas of TP53-associated tissue remodeling defines a multicellular tumor ecosystem in lung adenocarcinoma” “Single cell profiling of human airway identifies tuft-ionocyte progenitor cells displaying cytokine-dependent differentiation bias in vitro” “Single-cell dissection of the genotype-immunophenotype relationship in glioblastoma” “Glioblastoma shift from bulk to infiltrative growth is guided by plexin-B2-mediated microglia alignment in invasive niches” “Oncofetal reprogramming drives phenotypic plasticity in WNT-dependent colorectal cancer” “NOTCH1 drives sexually dimorphic immune responses in hepatocellular carcinoma” “Microglia and monocyte-derived macrophages drive progression of pediatric high-grade gliomas and are transcriptionally shaped by histone mutations” “Single cell view of tumor microenvironment gradients in pleural mesothelioma” “Hypoxia drives shared and distinct transcriptomic changes in two invasive glioma stem cell lines” Alexander Tsankov | Cancer Cell Biology | Best Researcher Award
Alexander Tsankov is a leading researcher in computational biology and cancer genomics, known for his contributions to single-cell and spatial transcriptomics. He holds dual bachelor’s degrees in Plan II Honors and Electrical and Computer Engineering from the University of Texas at Austin, and earned his M.S. and Ph.D. in Electrical Engineering and Computer Science from MIT. His research focuses on understanding the cellular and molecular mechanisms underlying cancer progression and tissue remodeling, with an emphasis on glioblastoma, lung adenocarcinoma, and colorectal cancer. Dr. Tsankov has published extensively in top-tier journals such as Nature, Nature Communications, Cancer Discovery, Nature Genetics, and Immunity. He has authored over 50 peer-reviewed publications, with an h-index of 36 and more than 15,000 citations according to Google Scholar. His work has earned him several prestigious honors, including the NIH NRSA postdoctoral fellowship and the NSF graduate fellowship. Dr. Tsankov frequently serves as a senior or corresponding author, highlighting his leadership in the field of computational oncology and single-cell genomics. Profile: Google Scholar Featured Publications: “Learning the cellular origins across cancers using single-cell chromatin landscapes” “Cellular and spatial atlas of TP53-associated tissue remodeling defines a multicellular tumor ecosystem in lung adenocarcinoma” “Single cell profiling of human airway identifies tuft-ionocyte progenitor cells displaying cytokine-dependent differentiation bias in vitro” “Single-cell dissection of the genotype-immunophenotype relationship in glioblastoma” “Glioblastoma shift from bulk to infiltrative growth is guided by plexin-B2-mediated microglia alignment in invasive niches” “Oncofetal reprogramming drives phenotypic plasticity in WNT-dependent colorectal cancer” “NOTCH1 drives sexually dimorphic immune responses in hepatocellular carcinoma” “Microglia and monocyte-derived macrophages drive progression of pediatric high-grade gliomas and are transcriptionally shaped by histone mutations” “Single cell view of tumor microenvironment gradients in pleural mesothelioma” “Hypoxia drives shared and distinct transcriptomic changes in two invasive glioma stem cell lines”