Dr. Xue Li , Institute of Chemistry Chinses Academy of Sciences , China
Dr. Xue Li is an Assistant Researcher at the Institute of Chemistry, Chinese Academy of Sciences, specializing in the design and application of functional carbon nanomaterials in biomedical fields. She holds a Bachelor’s degree from Sichuan University (2009-2013) and a PhD from the Institute of Chemistry, Chinese Academy of Sciences (2013-2018). Since 2018, Dr. Li has contributed significantly to the development of nanomaterial-based therapies for various diseases, particularly focusing on cancer, diabetes, and neurodegenerative diseases. Her work is characterized by innovative approaches to developing fullerene-based nanoparticles for therapeutic purposes. Dr. Li has published extensively in high-impact journals and is a recognized leader in her field, collaborating with national and international experts to drive forward the potential of nanomaterials in medicine.
Publication Profile:
Orcid
Strengths for the Award:
Dr. Xue Li stands out for her groundbreaking research on the design and biomedical application of functional carbon nanomaterials, particularly fullerenes, for treating complex diseases. Her work explores innovative therapeutic strategies, such as targeting inflammation, oxidative stress, and immune responses to address conditions like cancer, diabetes, and neurodegenerative diseases. Dr. Li has authored multiple high-impact journal publications, demonstrating her deep expertise in nanomaterials and their integration into medical treatments. Her contributions, such as reducing neuroinflammation to alleviate Parkinson’s disease and mitigating immune-mediated liver injury, showcase her ability to translate scientific knowledge into real-world solutions. Dr. Li’s collaborative approach and her role in advancing nanomedicine highlight her as a leading figure in her field.
Areas for Improvement:
While Dr. Li’s work is exceptional, expanding her research into more diverse therapeutic areas, such as cardiovascular diseases or neurodegenerative conditions like Alzheimer’s, could further broaden the impact of her research. Additionally, exploring the scalability and commercialization of her nanomaterial-based therapies would be a valuable direction for future development.
Education:
Dr. Xue Li completed her Bachelor’s degree in Chemistry at Sichuan University in June 2013. She pursued her Ph.D. at the Institute of Chemistry, Chinese Academy of Sciences, from 2013 to 2018, focusing on the design and application of nanomaterials, particularly fullerenes, for medical applications. During her doctoral studies, she gained significant experience in the synthesis, functionalization, and biomedical use of carbon nanomaterials. Dr. Li’s research laid the foundation for her current work as an Assistant Researcher at the Institute of Chemistry, Chinese Academy of Sciences, a position she has held since 2018.
Experience:
Dr. Xue Li has worked extensively in the field of nanomaterials, contributing to significant advancements in the application of fullerene-based nanoparticles for biomedical purposes. Since 2018, she has been an Assistant Researcher at the Institute of Chemistry, Chinese Academy of Sciences, where her research focuses on the development of functional nanomaterials for the treatment of diseases such as cancer, diabetes, and neurodegenerative disorders. Dr. Li has worked on several high-impact projects, including designing inflammation-targeting nanoparticles and investigating their roles in regulating immune responses and improving disease outcomes. Her experience spans both experimental techniques in nanomaterial synthesis and in vivo therapeutic applications. Additionally, Dr. Li has collaborated with multiple research institutions globally and has been recognized for her contributions to advancing nanomedicine.
Research Focus:
Dr. Xue Li’s research focuses on the design, synthesis, and biomedical applications of functional carbon nanomaterials, particularly fullerenes and their derivatives. Her work aims to develop innovative therapeutic strategies, leveraging the unique properties of these nanomaterials to address complex medical challenges, including cancer, autoimmune diseases, and neurodegenerative disorders. She is particularly interested in creating nanoparticles that target specific cellular pathways, such as inflammation and oxidative stress, to improve therapeutic outcomes. Dr. Li’s research includes the development of nanoparticles that can modulate macrophage differentiation and mitigate conditions like rheumatoid arthritis, autoimmune hepatitis, and neuroinflammation. By focusing on the functionalization of fullerenes, her work also explores how these materials can be used to treat insulin resistance and neurodegenerative diseases such as Parkinson’s.
Publications Top Notes:
- 🧬 Fullerenols hijack lysosomes to disrupt inter-organellar crosstalk and block autophagy pre-activated by mTOR inhibitors for cancer cell PANoptosis. Sci. Bull. 2025
- 💊 Inflammation-targeting fullerene nanoparticles dually inhibit macrophage and osteoclast differentiation for mitigating rheumatoid arthritis. CCS Chem. 2024
- 🔬 Curdlan decorated fullerenes mitigate immune-mediated hepatic injury for autoimmune hepatitis therapeutics via reducing macrophage infiltration. ACS Appl. Mater. Interfaces 2024
- 💡 The application of nanomaterials in the treatment of pancreatic-related diseases. Int. J. Mol. Sci. 2024
- 🧠 Oral [60] fullerene reduces neuroinflammation to alleviate Parkinson’s disease via regulating gut microbiome. Theranostics 2023
- 🍏 Dual regulation on oxidative stress and endoplasmic reticulum stress by [70] fullerenes for reversing insulin resistance in diabetes. Nano Today 2022
- 🔬 Gadofullerene Nanoparticles Extend Survival Rate and Down-Regulate Thrombin Expression in Orthotopic Pancreatic Cancer. Sci. China Mater. 2022
- 🩸 Gadofullerene Nanoparticles Reverse Dysfunctions of Pancreas and Improve Hepatic Insulin Resistance for Type 2 Diabetes Mellitus Treatment. ACS Nano 2019
- 🌱 Biomaterials: Application of Nanomaterials in the Treatment of Pancreatic-Related Diseases. Biomaterials 2018
Conclusion:
Dr. Xue Li’s exceptional research on functional nanomaterials and their applications in medicine, particularly in cancer, autoimmune diseases, and neurodegeneration, makes her a strong contender for the Research for Best Researcher Award. Her innovative approaches, contributions to high-impact journals, and dedication to advancing nanomedicine provide a solid foundation for future breakthroughs.