Prof. Yidong Wei | Immunology Cellular Interactions | Best Researcher Award

Prof. Yidong Wei , Shanghai Tenth People’s Hospital, Tongji University , China

Dr. Yidong Wei, M.D., Ph.D., FACC, is a distinguished professor and the Chief of Cardiology at Shanghai Tenth People’s Hospital, Tongji University. He also holds a clinician management role at the Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford. With a strong foundation in both clinical and translational research, Dr. Wei has built an internationally recognized career focused on interventional cardiology, cardiac electrophysiology, and cardiovascular epidemiology. He is a Fellow of the American College of Cardiology, reflecting his global academic influence. Known for bridging clinical care with bench-side discovery, his work has advanced understanding in myocardial infarction, heart failure, and calcium signaling in cardiomyocytes. With numerous high-impact publications and leadership in multicenter registries like NOAFCAMI-SH, Dr. Wei’s contributions are widely cited and clinically relevant. His dual academic and clinical roles across China and the UK highlight his dedication to innovation, international collaboration, and excellence in cardiovascular medicine.

Publication Profile:

Scopus

✅ Strengths for the Award:

1. High-Impact Research Output:
   Dr. Wei has authored or co-authored more than 18 recent peer-reviewed publications in prestigious journals such as Diabetes Metabolism Research and Reviews, Redox Biology, Cardiovascular Diabetology, and ESC Heart Failure. Many of these works are already cited, indicating early academic impact and relevance.

2. Dual Focus – Basic and Clinical Science:
   His research bridges the gap between molecular mechanisms (e.g., calcium signaling, TRIM21, PTEN) and clinical cardiology (e.g., atrial fibrillation, myocardial infarction, cardiac remodeling), highlighting a robust translational focus.

3. Leadership and Collaboration:
   He serves as Chief of Cardiology at Shanghai Tenth People’s Hospital and a Clinician Manager at the University of Oxford, demonstrating international leadership and cross-border collaboration.

4. Registry Leadership (NOAFCAMI-SH):
   His work through the NOAFCAMI-SH registry provides real-world evidence on cardiovascular disease progression, risk prediction, and treatment response—critical for patient-centered care.

5. Prestigious Recognition:
   Dr. Wei is a Fellow of the American College of Cardiology (FACC), a title reserved for top-tier cardiovascular professionals with sustained excellence.

⚠️ Areas for Improvement:

1. Broader International Research Leadership:
   While Dr. Wei has strong China–UK collaborations, leading global multicenter clinical trials or international consortia would further solidify his standing.

2. Public Engagement and Knowledge Translation:
   Though academically prolific, increased involvement in public health education or policy advocacy could amplify the real-world impact of his research.

3. Mentorship Track Record Visibility:
   Highlighting mentorship of junior researchers and postdocs more explicitly in profiles and bios would enhance his case for a holistic academic leadership award.

🎓 Education:

Dr. Wei began his medical education at Henan Medical University, where he completed clinical training with a focus on cardiovascular medicine. Driven by a passion for research, he pursued and completed his Ph.D. in 2004, with a specialization in cardiac electrophysiology and calcium signaling pathways. His graduate studies were complemented by advanced basic science training at the University of Kentucky, USA, a leading institution in biomedical research. Between 2004 and 2006, Dr. Wei completed postdoctoral research, focusing on the molecular mechanisms of cardiac dysfunction and electrophysiology. His educational background reflects a balanced integration of rigorous clinical education and innovative research development, equipping him with the tools necessary to bridge bedside care with laboratory insights. This foundation has allowed Dr. Wei to contribute to both academic medicine and cutting-edge cardiovascular research, distinguishing him as a leader with comprehensive and global training in the field.

🏥 Experience:

With over two decades of experience, Dr. Yidong Wei serves as Professor and Chief of the Department of Cardiology at Shanghai Tenth People’s Hospital, Tongji University. His role extends internationally, acting as Clinician Manager at the University of Oxford’s Centre for Diabetes, Endocrinology and Metabolism. His clinical expertise spans interventional cardiology, acute coronary syndromes, and electrophysiological interventions, while his research roles emphasize trial design, biomarker discovery, and cellular cardiology. He has led and contributed to large-scale registries like NOAFCAMI-SH, generating evidence that informs guidelines for myocardial infarction and atrial fibrillation. His professional experience combines healthcare leadership, cross-border academic collaboration, and impactful research. As a Fellow of the American College of Cardiology, he is actively engaged in academic societies and peer-reviewed journals. Dr. Wei’s experience reflects an enduring commitment to patient care, innovation in research, and mentorship of future cardiology leaders, marking him as a high-impact contributor in his field.

🔬 Research Focus:

Dr. Yidong Wei’s research lies at the intersection of clinical cardiology and molecular medicine. He focuses on interventional cardiology, atrial fibrillation, myocardial infarction, and calcium signaling pathways in cardiac myocytes. A major theme in his work is the electrophysiological basis of heart failure and age-related changes in ventricular function. Using techniques like patch clamping, calcium imaging, laser confocal microscopy, and molecular biology, he investigates calcium channel regulation and excitation-contraction coupling in cardiac cells. Clinically, he leads research through the NOAFCAMI-SH registry, analyzing systemic inflammation, hyperglycemia, atrial fibrillation, and long-term cardiac outcomes. His work advances the understanding of post-infarction remodeling and atrial pathology. Combining basic science with real-world data, Dr. Wei’s research bridges gaps in translational cardiology and offers therapeutic targets for chronic cardiac conditions. His integrative approach makes him a pioneer in translating bench findings into bedside impact, with potential to redefine cardiac care strategies globally.

📚 Publications Top Notes:

1. 📈 Association of stress hyperglycemia ratio with atrial fibrillation and outcomes in myocardial infarction

2. 🧪 Prognostic implications of systemic immune-inflammation index in MI patients with and without diabetes

3. 🧬 TRIM21 deficiency protects heart post-MI by reducing oxidative stress

4. 🫀 4S-AF scheme for characterizing atrial fibrillation after myocardial infarction

5. 🔬 TRIM21 worsens cardiac injury via M1 macrophage polarization post-MI

6. 🧮 Stress hyperglycemia and outcomes in MI with and without diabetes mellitus

7. 💉 ZPI protects endothelium via PI3K/Akt pathway activation against ox-LDL

8. 📊 Atrial fibrillation’s prognosis across heart failure subtypes post-MI

9. 🕒 Five-year outcomes post left atrial appendage occlusion

10. 🧫 PTEN and serum deprivation-induced cytotoxicity via PI3K/AKT pathway

🧾 Conclusion:

Dr. Yidong Wei stands out as a highly suitable candidate for the Best Researcher Award. His contributions to cardiovascular research—spanning cutting-edge basic science to influential clinical trials—are both innovative and impactful. His leadership roles, international presence, and translational focus align perfectly with the goals of this prestigious recognition. Given his trajectory, Dr. Wei is not only a leader in current cardiovascular research but also a driver of future scientific breakthroughs.