Sirish Kumar Palle | RNA Biology Function | Best Researcher Award

Dr. Sirish Kumar Palle | RNA Biology Function | Best Researcher Award

Dr. Sirish Kumar Palle | Oklahoma University Health Sciences Center | United States

Dr. Sirish Kumar Palle, MBBS, MD, is an Associate Professor in the Department of Pediatrics at the University of Oklahoma College of Medicine. Specializing in Pediatric Gastroenterology, Hepatology, and Nutrition, he combines clinical expertise with innovative research. With a strong focus on liver diseases in children, Dr. Palle is dedicated to advancing understanding and treatment of metabolic dysfunction-associated steatotic liver disease (MASLD), pediatric autoimmune liver disorders, and cystic fibrosis liver disease. His multidisciplinary approach integrates clinical care and translational research, aiming to improve outcomes for pediatric patients. Dr. Palle is a respected educator and clinician-educator, actively involved in mentoring emerging researchers and contributing extensively to peer-reviewed literature. His work has garnered national recognition through travel awards and presentations at major symposia. Passionate about bridging bench-to-bedside discoveries, Dr. Palle’s contributions have significantly impacted pediatric hepatology research and care standards.

Publication Profile: 

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Education:

Dr. Sirish Kumar Palle earned his MBBS and MD degrees, followed by specialty training in Pediatrics through the Royal College of Pediatrics & Child Health, United Kingdom. He further advanced his clinical skills during his residency at the University of South Alabama’s Department of Pediatrics. Committed to subspecialty expertise, Dr. Palle completed a prestigious fellowship in Pediatric Gastroenterology, Hepatology, and Nutrition at Emory University, Atlanta. This extensive postgraduate training equipped him with advanced knowledge in pediatric liver and gastrointestinal disorders, nutrition, and hepatobiliary diseases. His formal education combined international perspectives, rigorous clinical training, and cutting-edge research methodologies, laying a robust foundation for his academic and clinical career in pediatric gastroenterology and hepatology.

Experience:

Dr. Palle serves as an Associate Professor in the Department of Pediatrics at the University of Oklahoma, where he is a clinician-educator specializing in pediatric gastroenterology and hepatology. His clinical experience includes managing complex pediatric liver diseases such as MASLD, autoimmune hepatitis, and cystic fibrosis-related liver complications. He practices at OU Children’s Physicians, providing expert care to children with chronic liver and pancreatic disorders. Dr. Palle’s research experience spans translational studies on novel serum biomarkers, clinical risk classification, and therapeutic interventions for pediatric liver diseases. He actively participates in national and international collaborations and serves as a mentor for junior researchers and medical trainees. Dr. Palle has presented at numerous professional symposia and contributed extensively to peer-reviewed journals. His role blends clinical practice, research, and education, emphasizing improved diagnostic and treatment strategies in pediatric hepatology.

Awards and Honors:

Dr. Palle has received multiple prestigious awards recognizing his contributions to pediatric hepatology research. Notably, he earned the Cincinnati Children’s Hospital Medical Center Travel  for his work presented at the Pediatric Autoimmune Liver Disease Symposium. Additionally, he was honored with the Frontiers in Pediatric Pancreatology  from NASPGHAN, reflecting his impact in pancreatic and liver research. His ongoing research efforts and clinical expertise have gained national and international recognition. These awards highlight his commitment to advancing pediatric liver disease understanding and treatment. Dr. Palle’s scholarly impact is further validated by his authorship of numerous influential publications and active participation in multi-center studies. His dedication to research excellence and mentorship continues to foster innovation in pediatric gastroenterology.

Research Focus:

Dr. Palle’s research primarily focuses on pediatric liver diseases, with special emphasis on metabolic dysfunction-associated steatotic liver disease (MASLD), autoimmune liver disorders, and cystic fibrosis-related liver complications. His work explores novel serum biomarkers for liver health assessment and the pathophysiology of pediatric liver diseases. He investigates clinical risk stratification models and therapeutic interventions to improve patient outcomes. His translational research bridges molecular mechanisms and clinical applications, contributing to early diagnosis, disease monitoring, and treatment strategies. Dr. Palle also studies lipid metabolism and inflammatory pathways in pediatric liver disease progression. Through collaboration in large, real-world cohorts and clinical trials, he contributes to refining disease nomenclature and improving consensus definitions. His research has enhanced understanding of pediatric hepatology and informed clinical guidelines. Dr. Palle is committed to integrating innovative scientific discoveries into clinical practice, improving the quality of care for children with liver diseases worldwide.

Publications Top Notes: 

  1.  A Comparison of Novel Serum Markers of Liver Health in Adolescents With Metabolic Dysfunction-Associated Steatotic Liver Disease

  2.  Oxidized HDL and LDL in Adolescents with Obesity and Metabolic Dysfunction-Associated Steatotic Liver Disease

  3.  Serum Adropin is Unaltered in Adolescents with Histology-Confirmed Steatotic Liver Disease

  4.  Concordance of MASLD and NAFLD Nomenclature in Youth in the TARGET-NASH Real-World Cohort

  5.  Gly-β-MCA as a Potent Anti-Cholestasis Agent in Mice with Biliary Injury

  6.  Advanced Cystic Fibrosis Liver Disease: Endovascular, Endoscopic, Radiologic, and Surgical Considerations

  7.  Validation of a Clinical Risk-Based Classification System in a Large NAFLD Cohort

  8.  Postprandial Triglycerides and FGF19 as Potential Screening Tools for Pediatric NAFLD

  9.  Pediatric Autoimmune Pancreatitis: A Single-Center Retrospective Case Series

  10.  Gastric Duplication Cyst Case Study in Pediatrics

Conclusion:

Overall, Dr. Sirish Kumar Palle is a highly suitable candidate for the Best Researcher Award based on his substantial and focused contributions to pediatric hepatology research, demonstrated by a strong publication record, leadership in clinical research, and recognition by peer institutions. His work is characterized by clinical relevance and scientific rigor, addressing significant pediatric health issues with an emphasis on liver disease. With targeted enhancements such as increased grant acquisition, broader interdisciplinary collaborations, and further professional visibility, Dr. Palle’s already distinguished research career can achieve even greater impact and recognition. Nonetheless, as it stands, he exemplifies the qualities of a dedicated, productive, and impactful clinician-scientist deserving of such an honor.