Felicia ANTOHE | Molecular Mechanisms Signaling | Molecular Cell Biology Award

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Dr. Felicia ANTOHE | Molecular Mechanisms Signaling | Molecular Cell Biology Award

Dr. Felicia ANTOHE , Inst. Cellular Biology and Pathology NS , Romania

Dr. Felicia Antohe is the Head of the Proteomics Department at the Institute of Cellular Biology and Pathology, Romanian Academy. With a background in cellular biology and biophysics, she has contributed significantly to biomedical research, particularly in vascular endothelium, atherosclerosis, diabetes, and immune disorders. She has received multiple prestigious awards and conducted pioneering research, especially on the transcytosis of macromolecules in endothelial cells. As a PhD advisor, she mentors young researchers, having guided 12 PhD students to date. Dr. Antohe is an internationally recognized expert with extensive experience in immunology, cell biology, and proteomics.

Publication Profile:

Google Scholar

Strengths for the Award:

Dr. Felicia Antohe stands out as an exceptional candidate for the Research for Molecular Cell Biology Award due to her extensive academic and research achievements. As Head of the Proteomics Department at the Institute of Cellular Biology and Pathology, Romanian Academy, her leadership in pioneering research in endothelial cell biology and vascular pathologies has been transformative. Dr. Antohe’s strong academic background, with a Master’s in Biophysics and a PhD in Cellular Biology, complements her robust research portfolio. With over 170 scientific papers, 90 of which are indexed in Web of Science, she is recognized for her contributions to molecular mechanisms in diseases such as atherosclerosis, diabetes, and immune disorders. Furthermore, her work on monoclonal antibodies and proteomics has had a significant impact on both scientific and clinical advancements.

Areas for Improvement:

While Dr. Antohe’s research is highly regarded, there is potential for greater integration of her research with cutting-edge technologies in bioinformatics and computational biology. This could further expand her work on proteomics and molecular mechanisms. Additionally, there is an opportunity for broader outreach to apply her findings in practical therapeutic contexts through collaborations with pharmaceutical companies or clinical trials. Expanding her influence in translational research could have a larger impact on public health, especially in diseases such as diabetes and cardiovascular disorders.

Education:

Dr. Felicia Antohe holds a Master’s degree in Biophysics from the University of Bucharest (1977). She completed her PhD in Cellular Biology at the Romanian Academy’s Institute of Cellular Biology and Pathology (1994). In addition to her formal education, she has been a PhD coordinator since 2000 and has contributed significantly to research training at national and international levels. Her work blends theoretical knowledge with cutting-edge lab techniques in molecular biology, proteomics, and immunology.

Experience:

Dr. Antohe’s research experience spans numerous roles. She is currently the Principal Investigator and Member of the Scientific Council at the Romanian Academy’s Institute of Cellular Biology and Pathology. She has also worked as a visiting scientist at prestigious institutions like McGill University, University of Alberta, and Max Planck Institute. She has coordinated over 44 research projects, including national and international grants, and is actively involved in multiple collaborative research efforts across Europe and beyond. Her leadership in cell biology and proteomics is widely recognized.

Awards and Honors:

Dr. Antohe has received numerous awards, including the EURESCO Prize (2001), the BIO-RAD Laboratories Prize for valuable research (2002), and the Romanian Academy Emil Racovita Prize (1991). She has also won multiple international recognitions for her scientific contributions, such as the Best Poster award at the “8th International Conference on Vascular Endothelium” (2005), and various fellowships and grants from organizations like COST and the European Science Foundation.

Research Focus:

Dr. Antohe’s research focuses on endothelial cell biology, particularly transcytosis, endocytosis, and cell receptor mechanisms in both health and disease. She investigates the bio-pathology of atherosclerosis, diabetes, and immune disorders, with particular attention to the transport of macromolecules across vascular cells. Her work also explores the role of monoclonal antibodies as diagnostic and therapeutic tools. She applies proteomic techniques to study endothelial cell function, aiming to understand vascular biology at molecular and cellular levels.

Publications Top Notes:

  • The MHC class I-related receptor, FcRn, plays an essential role in the maternofetal transfer of γ-globulin in humans 📄
  • Functional expression of the MHC class I-related receptor, FcRn, in endothelial cells of mice 📄
  • Transcytosis of plasma macromolecules in endothelial cells: a cell biological survey 📄
  • Expression of functionally active FcRn and the differentiated bidirectional transport of IgG in human placental endothelial cells 📄
  • Analytical techniques for multiplex analysis of protein biomarkers 📄
  • Functional ultrastructure of the vascular endothelium: changes in various pathologies 📄
  • Effect of enoxaparin on high glucose-induced activation of endothelial cells 📄
  • Albumin-binding proteins function in the receptor-mediated binding and transcytosis of albumin across cultured endothelial cells 📄
  • Carbapenemase-Producing Klebsiella pneumoniae in Romania: A Six-Month Survey 📄
  • Establishment of a pure vascular endothelial cell line from human placenta 📄

Conclusion:

Dr. Felicia Antohe is an outstanding researcher whose work has greatly advanced our understanding of endothelial cell biology, molecular transport, and disease mechanisms. Her combination of technical expertise, leadership in multiple high-impact research projects, and numerous prestigious awards positions her as an ideal candidate for the Research for Molecular Cell Biology Award. While there is always room to expand her research applications, her contributions to science are already substantial and impactful.

 

 

 

Jiaqiang Huang | Molecular Mechanisms Signaling | Best Researcher Award

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Assoc. Prof. Dr. Jiaqiang Huang | Molecular Mechanisms Signaling | Best Researcher Award

Assoc. Prof. Dr. Jiaqiang Huang , China Agricultural University , China

Dr. Huang JQ is an associated professor at China Agricultural University, specializing in animal nutrition, food science, and health. With a strong background in selenium and selenoproteins, Dr. Huang has made significant contributions to understanding their biological effects, particularly in livestock and poultry production. His work explores the prevention and regulation of oxidative stress, intestinal health, and the development of selenium-rich products. Dr. Huang is recognized for his expertise in molecular regulation mechanisms and has published extensively in top-tier journals. He also holds several leadership positions in academic research, contributing to global advances in animal nutrition and health.

Publication Profile:

Scopus

Strengths for the Award:

  1. Extensive Academic Background: Dr. Huang JQ has a comprehensive academic foundation, having completed a Bachelor’s, Master’s, and Doctoral degree in relevant fields, such as Animal Nutrition, Human Health, and Food Science, from prestigious institutions like Yangzhou University, Sichuan Agricultural University, and China Agricultural University. His consistent academic progress over the years reflects his deep commitment and passion for his field.
  2. Expertise in Selenium and Selenoproteins Research: Dr. Huang’s research is centered around the biological effects of selenium and selenoproteins, with a particular focus on their molecular regulation mechanisms and their role in preventing oxidative stress in livestock and poultry. This expertise is highly significant, given the potential of selenium to improve animal health and productivity, contributing to sustainable and efficient agricultural practices.
  3. Pioneering Work in Intestinal Health and Oxidative Stress: His research contributes significantly to understanding how oxidative stress impacts livestock and poultry health and how selenium can serve as a mitigating factor. This aligns with the current need to develop sustainable approaches for livestock health management, including reducing the reliance on antibiotics and improving gut health.
  4. Impressive Publication Record: Dr. Huang has published numerous high-impact papers in reputed journals such as Nutrients, Advanced Science, J Nutr, and Redox Biol, among others. His work has led to several innovative discoveries, particularly in areas like ferroptosis modulation, radiation resistance, and metabolic disorders, showing his versatility in addressing complex issues in animal nutrition and health.
  5. Collaborative Approach and Leadership: As an associate professor at China Agricultural University, Dr. Huang has not only contributed through his individual research but also led and collaborated on numerous interdisciplinary projects. His research is cited extensively, highlighting his leadership and influence within the scientific community.
  6. Global Impact and Relevance: Dr. Huang’s work on selenium-enriched probiotics, selenium-based nanocomposites, and oxidative stress management has the potential for global impact, addressing issues such as malnutrition, oxidative damage, and metabolic diseases. His research is timely and aligns with global health and agricultural goals, making him a highly relevant figure in the research community.

Areas for Improvement:

  1. Broader Outreach of Research Findings: While Dr. Huang’s publications are impressive, there may be a need for more active engagement with non-academic audiences, including policy-makers, industry stakeholders, and the public. Translating his research findings into practical applications in agricultural practices and public health could enhance the societal impact of his work.
  2. Expanding Interdisciplinary Collaborations: While Dr. Huang has a strong background in nutrition and health, future work could benefit from increased collaboration with researchers from other fields such as genetic engineering, microbiology, and environmental sciences. This could help broaden the scope of his research and address complex global issues such as climate change, sustainable agriculture, and bioengineering.
  3. Diversifying Research Focus: Although selenium research is central to Dr. Huang’s work, diversifying into related fields, such as personalized nutrition or the development of innovative biotechnological solutions for sustainable farming, could open up new avenues for his research and expand its applicability in diverse agricultural and medical contexts.

Education

Dr. Huang completed his Bachelor’s in Animal Nutrition from Yangzhou University in 2009. He earned a Master’s in Animal Nutrition and Human Health from Sichuan Agricultural University in 2012. He obtained a Doctorate in Food Science from China Agricultural University in 2015, followed by postdoctoral work at the same institution from 2016 to 2020. As an associated professor since 2020, Dr. Huang has further advanced his research into selenium’s role in livestock and human health.

Experience

Dr. Huang’s research journey began in 2015 with a doctoral focus on food science, followed by postdoctoral research at China Agricultural University. He became an associated professor in 2020, continuing his exploration of selenium’s effects on oxidative stress, intestinal health, and nutrition. His research has led to multiple groundbreaking publications in top journals. With a career dedicated to academic research, Dr. Huang collaborates with international experts, leads innovative projects, and educates future scholars in animal nutrition and food science.

Research Focus

Dr. Huang’s research is focused on the biological effects of selenium and selenoproteins in livestock and poultry, with a particular emphasis on oxidative stress regulation, intestinal health, and selenium-rich products. His work investigates molecular mechanisms behind selenium’s impact on animal health, exploring its potential to improve resistance to diseases and oxidative damage. By developing selenium-enriched products, Dr. Huang aims to enhance livestock and poultry production efficiency while promoting human health. His interdisciplinary approach combines nutrition, molecular biology, and food science to advance the field.

Publications Top Notes:

  1. Advances of Selenium in Poultry Nutrition and Health
  2. Amelioration of LPS-induced Jejunum Injury and Mucus Barrier Damage in Mice by IgY Embedded in W/O/W Emulsion
  3. Roles of Probiotics, Prebiotics, and Postbiotics in B-cell Mediated Immune Regulation
  4. Protective Effect of IgY Embedded in W/O/W Emulsion on LPS Enteritis-Induced Colonic Injury in Mice
  5. Effect of Selenium and Selenoproteins on Radiation Resistance
  6. SELENOI Functions as a Key Modulator of Ferroptosis Pathway in Colitis and Colorectal Cancer
  7. Hepatocyte-specific Selenoi Deficiency Predisposes Mice to Hepatic Steatosis and Obesity
  8. Stabilization by Chaperone GroEL in Biogenic Selenium Nanoparticles Produced from Bifidobacterium animalis H15 for the Treatment of DSS-Induced Colitis
  9. Biomimetic MicroRNAs-Selenium-Nanocomposites for Targeted and Combined Hyperlipidemia Therapy
  10. Protective Effects of Selenium Nanoparticles Against Bisphenol A-Induced Toxicity in Porcine Intestinal Epithelial Cells

Conclusion:

Dr. Huang JQ is a highly deserving candidate for the Best Researcher Award due to his expertise in the biological effects of selenium and selenoproteins, his innovative research in animal nutrition, and his leadership in advancing scientific knowledge in oxidative stress management and intestinal health. His extensive publication record, interdisciplinary collaborations, and potential to impact global agricultural and health practices further strengthen his candidacy. While there are areas for improvement in outreach and diversification, his work is impactful and has the potential for long-lasting contributions to both science and society.