Laure VINCENT | Immunology Cellular Interactions | Best Research Article Award

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Dr. Laure VINCENT | Immunology Cellular Interactions | Best Research Article Award

Dr. Laure VINCENT, CHU de Montpellier , France

Dr. Laure Vincent is a distinguished hematologist at the CHU de Montpellier, specializing in clinical hematology. With a focus on multiple myeloma and stem cell transplantation, she is recognized for her extensive research and clinical expertise. She is affiliated with the Hôpital St Eloi, Montpellier, where she actively contributes to advancing treatments in hematologic malignancies. Dr. Vincent has a profound commitment to patient care and an established career in the hematology field, making notable contributions to both the scientific and medical communities.

Publication Profile: 

Google Scholar

Strengths for the Award:

  1. Extensive Research Contribution: Dr. Vincent has made significant contributions to the field of hematology, with numerous publications in renowned journals such as Leukemia, Bone Marrow Transplantation, Haematologica, and Blood Cancer Journal. Her research has focused on critical topics like multiple myeloma, hematopoietic stem cell transplantation, and the treatment of myelodysplastic syndromes.

  2. Innovative and Impactful Studies: Many of her studies highlight novel findings that contribute to the understanding and management of hematological diseases. For instance:

    • Her research on insulin as a myeloma cell growth factor (Leukemia, 2010) opened new avenues for treatment approaches.

    • The exploration of the therapeutic window for myeloma relapse after high-dose melphalan and stem cell transplantation (Oncotarget, 2012) shows an in-depth understanding of patient care in a post-transplant setting.

    • The retrospective study on hematopoietic stem cell transplantation in multiple myeloma patients from the Société Française de Greffe de Moelle et de Thérapie Cellulaire (Biol Blood Marrow Transplant, 2015) has crucial implications for treatment strategies in myeloma.

  3. Multidisciplinary Collaboration: Dr. Vincent has worked extensively with international research teams, reflecting her ability to collaborate and contribute to large-scale studies and multicenter trials. This is evident in studies such as the ones published with the Société Française de Greffe de Moelle et de Thérapie Cellulaire and the Eurocord/ALWP-EBMT study.

  4. Comprehensive Educational Impact: In addition to her research, Dr. Vincent has contributed significantly to the education and training of healthcare professionals, particularly in oncology and hematology. Her work in developing educational content for nurses and students in the field of Onco-Hematology demonstrates her commitment to advancing clinical knowledge.

Areas for Improvement:

  1. Wider Dissemination of Findings: While Dr. Vincent’s research has been highly impactful within the specialized field of hematology, her findings could benefit from broader dissemination. This could include collaborations with non-medical fields or publishing findings in more general medical journals to reach a wider audience.

  2. Focus on Translational Research: Although Dr. Vincent’s research primarily focuses on clinical outcomes and therapies, incorporating more translational research—bridging the gap between bench and bedside—could further enhance her work. Research on biomarkers for early detection, for example, would benefit the field of personalized medicine.

  3. Long-Term Impact Studies: Some of Dr. Vincent’s studies are focused on the immediate or short-term effects of therapies. It would be valuable to see more research that addresses the long-term outcomes of treatments in hematological diseases, especially in terms of quality of life and survival rates over decades.

Education:

Dr. Vincent’s educational journey began with secondary studies at the Lycée International de Grenoble, where she earned a scientific baccalaureate with distinction in 1999. She then pursued her medical degree at the University of Grenoble (1999-2006), followed by specialized training in hematology. Dr. Vincent is fluent in English, holding Cambridge Certificates in Advanced and Proficiency English. Additionally, she holds certifications in business English and advanced clinical training in hematology.

Experience:

Dr. Laure Vincent has extensive clinical experience in the field of hematology, particularly in hematopoietic stem cell transplantation. She has contributed to several impactful research studies, focusing on treatments for hematological malignancies like multiple myeloma and myelodysplastic syndromes. Dr. Vincent has published extensively in reputable journals, authored chapters in medical books, and presented her work at various prestigious international conferences, demonstrating her authority in the field. She also serves as an educator, contributing to the training of future healthcare professionals.

Research Focus:

Dr. Vincent’s research primarily focuses on hematological cancers, including multiple myeloma, myelodysplastic syndromes, and stem cell transplantation. Her studies explore innovative therapies, relapse prevention strategies, and mechanisms of drug resistance in these malignancies. Notable research topics include the use of monoclonal antibodies, the role of the bone marrow microenvironment, and the improvement of outcomes following hematopoietic stem cell transplantation. Her work aims to develop targeted therapies to improve patient survival rates and quality of life.

Publications Top Notes:

  1. “Insulin is a potent myeloma cell growth factor through insulin/IGF-1 hybrid receptor activation” (Leukemia, 2010) 🧬

  2. “Malignant plasma cells responsible for Multiple Myeloma relapse are detectable and survive seven days after high dose melphalan and stem cell transplantation” (Oncotarget, 2012) 🧪

  3. “Allo-SCT for philadelphia negative myeloproliferative neoplasms in blast phase” (Bone Marrow Transplant, 2014) 💉

  4. “HLA-matched Allogeneic SCT improves outcome of higher risk MDS” (Leukemia, 2015) 🩸

  5. “Drug metabolism and clearance system in tumor cells of patients with multiple myeloma” (Oncotarget, 2015) 💊

  6. “Low non-relapse mortality and long-term preserved quality of life in older patients undergoing matched related donor allogeneic stem cell transplantation” (Haematologica, 2015) 👩‍⚕️

  7. “Comparison of outcomes after unrelated cord blood and unmanipulated haploidentical stem cell transplantation in adults with acute leukemia” (Leukemia, 2015) 🔬

  8. “Hematopoietic Stem Cell Transplantation in Multiple Myeloma: A Retrospective Study” (Biol Blood Marrow Transplant, 2015) 🏥

  9. “Autologous Stem Cell Transplantation For Relapsed/Refractory Diffuse Large B Cell Lymphoma” (Bone Marrow Transplant, 2015) 🔄

  10. “Bing-Neel syndrome as a rare complication of Waldenström’s macroglobulinemia” (Haematologica, 2015) 🧠

Conclusion:

Dr. Laure Vincent’s research is exceptional, with a proven track record in advancing knowledge and treatment options in hematology. Her ability to lead large-scale studies, her contributions to important clinical findings, and her dedication to educating future healthcare professionals make her highly deserving of the “Best Research Article Award.” While there is always room for expanding the scope of research to include more translational and long-term impact studies, her work undoubtedly stands out as a significant contribution to hematological science.

Bárbara Verçosa | Host-Pathogen Interactions | Best Researcher Award

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Prof. Dr. Bárbara Verçosa | Host-Pathogen Interactions | Best Researcher Award

Prof. Dr. Bárbara Verçosa , Faculdade de Saude Pitágoras Codó , Brazil

Bárbara Laurice Araújo Verçosa, a Brazilian researcher and veterinarian, specializes in veterinary pathology and the study of leishmaniasis. She holds a Doctorate in Biology (2015) from Universidade Federal de Minas Gerais, with a focus on renal response in canine visceral leishmaniasis. She is a committed educator and scientific researcher, contributing extensively to the fields of veterinary medicine and animal pathology. She has published numerous papers in international journals, participated in various academic and professional events, and is an active member of editorial boards. Her contributions to veterinary science, especially in the study of inflammatory responses and apoptosis in leishmaniasis, have earned her recognition both nationally and internationally.

Publication Profile:

Scopus

Strengths for the Award:

  1. Academic Qualifications and Research Focus:
    Dr. Verçosa has a strong academic background, with a Doctorate in Biology from the Universidade Federal de Minas Gerais (UFMG) and a Master’s degree in Pathological Anatomy and Clinical Pathology from the same institution. Her research focuses on canine visceral leishmaniasis, which is highly relevant and impactful in veterinary medicine. Her expertise in apoptosis, inflammation, fibrosis, and renal pathology related to infectious diseases shows a high level of specialization and contribution to the field.
  2. Research Publications:
    Dr. Verçosa has an impressive publication record with 23 articles in reputable scientific journals, including high-impact journals such as Microbial Pathogenesis, Molecular Immunology, and Veterinary Parasitology. Additionally, she has authored books and chapters and has presented her research at numerous conferences. The breadth and depth of her publications demonstrate her active contribution to advancing knowledge in veterinary medicine, particularly in parasitic diseases.
  3. Experience and Knowledge:
    With significant experience in pathology, veterinary medicine, and molecular diagnostics, she brings a holistic understanding of both the basic and applied aspects of her field. Her experience in teaching, mentoring graduate students, and serving as a scientific journal referee further exemplifies her leadership in the academic and research community.
  4. Awards and Recognition:
    Dr. Verçosa’s work has been recognized with multiple awards such as the Menção Honrosa at the Seminário de Iniciação Científica and the 1st Prize in Scientific Initiation from Fapepi. These awards highlight her early career achievements and ongoing recognition in her research contributions.
  5. International Recognition and Collaborations:
    Dr. Verçosa is an active contributor to international research, with collaborations and refereeing roles in journals such as the Journal of Pharmaceutical Research International and the Asian Journal of Advances in Research, which reflects her international recognition and commitment to global scientific dialogue.

Areas for Improvement:

  1. Increase Interdisciplinary Collaborations:
    While Dr. Verçosa’s expertise is mainly within the veterinary and biological sciences domain, exploring interdisciplinary research with fields like public health, epidemiology, and clinical veterinary practices could further broaden the impact of her work, especially considering the public health implications of diseases like Leishmaniasis.
  2. Expanding Research into Novel Treatment Approaches:
    Given the ongoing challenges in treating Leishmaniasis in animals, expanding her research to explore new treatment protocols or innovative therapies in collaboration with clinicians could be a valuable area of growth. Exploring how her findings in inflammatory response and fibrosis can lead to better therapeutic options could strengthen the clinical relevance of her work.
  3. Increased Public Engagement:
    While her publications are substantial in academic circles, increasing public engagement through outreach programs or community awareness initiatives about canine Leishmaniasis and other diseases she studies could enhance her contribution to society. This could help bridge the gap between research and practical applications for the broader population.

Education:

Bárbara Verçosa holds a Doctorate (2015) in Biology from Universidade Federal de Minas Gerais (UFMG), Brazil, where she focused on inflammatory responses and apoptosis in dogs infected with Leishmania. She completed her Master’s in Pathological Anatomy and Clinical Pathology at UFMG in 2010, investigating apoptosis in naturally infected dogs. She earned her Veterinary Medicine degree from Universidade Federal do Piauí (UFPI) in 2007, specializing in the inflammatory responses in canine leishmaniasis. Additionally, Verçosa has participated in postdoctoral research at Universidade de Brasília (UnB), focusing on health sciences, and has completed several continuing education courses in diagnostic imaging, molecular diagnostics, and animal pathology.

Experience:

Verçosa has extensive academic and professional experience in veterinary medicine and pathology. She served as a faculty member at Universidade Regional do Cariri (URCA) and currently teaches at Faculdade de Ciências da Saúde Pitágoras Codó. She has been involved in research, graduate supervision, and clinical training in veterinary anatomy and pathology. Her research focus includes canine leishmaniasis, inflammatory responses, and apoptotic processes in infected tissues. Her career also includes several trainee and research positions, particularly in animal pathology at UFPI, and clinical practice in large animal surgery. Verçosa’s international exposure includes teaching and research roles at UFMG, where she taught pathology to veterinary students. Her involvement in research and scientific publication spans many years, with a focus on advancing the understanding of animal diseases through detailed anatomical and molecular studies.

Awards and Honors:

Bárbara Verçosa has received multiple awards for her research and academic contributions. Notably, she received two Honorable Mentions in 2006 for her presentations at the XIV Seminário de Iniciação Científica at UFPI. She was also awarded the 1st Prize for Scientific Initiation by Fapepi, the Foundation for Research Support of the State of Piauí, in 2005. These recognitions highlight her early dedication to scientific research. Verçosa’s career has also been distinguished by her scholarships from CAPES and CNPq, which supported her doctoral and master’s research. Her research excellence has been further validated by her ongoing involvement in prestigious journals as a reviewer, alongside her role in various editorial boards. Her academic achievements reflect her significant contributions to the fields of veterinary science and animal pathology.

Research Focus:

Bárbara Verçosa’s research primarily focuses on veterinary pathology, particularly in the context of visceral leishmaniasis in dogs. Her studies explore the inflammatory response, apoptosis, and fibrosis in organs affected by this parasitic disease. She investigates the molecular and histomorphometric changes in canine renal tissues, with an emphasis on the interactions between immune responses and tissue damage. Verçosa’s work also covers the role of chemokines, cytokines, and apoptosis markers in understanding the disease’s pathogenesis. Her research extends into other areas of veterinary pathology, including the study of animal inflammatory diseases and zoonotic diseases. Through her studies, she aims to contribute to improving diagnostic, therapeutic, and preventive measures for animal health. Verçosa’s interdisciplinary approach combines molecular biology, histopathology, and clinical studies, positioning her as a leading expert in veterinary parasitology.

Publications Top Notes:

  1. Enhanced apoptotic index in hepatocytes, Kupffer cells, and inflammatory infiltrate showed positive correlation with hepatic lesion intensity, parasite load, and clinical status in naturally Leishmania-infected dogs. (MICROBIAL PATHOGENESIS) 📚🦠
  2. MCP-1/IL-12 ratio expressions correlated with adventitial collagen depositions in renal vessels and IL4/IFN-γ expression correlated with interstitial collagen depositions in the kidneys of dogs with canine leishmaniasis. (MOLECULAR IMMUNOLOGY) 🧬🦠
  3. Nucleolar organizer region proteins enhancement in nucleoplasm’s of renal tubular cells is an indication of kidney impairment in Leishmania-infected dogs. (VETERINARY PARASITOLOGY) 🦠🧪
  4. Enhanced apoptotic index, chemokines and inflammatory recruitment in renal tissues shows relationship with the clinical signs in Leishmania-infected dogs. (VETERINARY PARASITOLOGY) 🔬🐶
  5. The balance between IL-12/IL4 in renal tissue switches the inflammatory response arm and shows relationship with the clinical signs in Leishmania-infected dogs (Veterinary Immunology and Immunopathology, 2021).

Conclusion:

Dr. Bárbara Laurice Araújo Verçosa is a highly accomplished and well-regarded researcher in the field of veterinary medicine, particularly in pathology and infectious diseases. Her extensive research publications, awards, and international collaborations are a testament to her expertise and impact in the field. The areas identified for improvement are relatively minor and pertain to enhancing the breadth and public visibility of her work. Overall, her scientific contributions make her an excellent candidate for the Best Researcher Award.