Shuxin Han | Molecular Mechanisms Signaling | Best Researcher Award

Dr. Shuxin Han | Molecular Mechanisms Signaling | Best Researcher Award

Dr. Shuxin Han | Xinjiang University | China

Dr. Shuxin Han is a distinguished molecular biologist and professor at Xinjiang University, widely recognized for his pioneering work in hepatobiliary and metabolic biology. With a research career spanning over two decades, Dr. Han has made major contributions to understanding how Kruppel-like factors, especially KLF15, regulate endobiotic and xenobiotic metabolism, impacting drug detoxification and metabolic disease mechanisms. He earned his Ph.D. from Kent State University and has held prestigious positions at Harvard Medical School and Case Western Reserve University. His groundbreaking studies have been published in high-impact journals like Nature Metabolism and Nature Communications, with several articles naming him as first or corresponding author. In addition to research, Dr. Han serves as a reviewer for top-tier journals in pharmacology, hepatology, and clinical science. He is also an academic leader, currently shaping the next generation of scientific talent and metabolic disease research in China.

Publication Profile: 

Scopus

Education:

Dr. Shuxin Han began his academic journey in Animal Sciences, earning a bachelor’s degree from Anhui Agricultural University (1994–1998). He advanced to a research assistant role at Peking University (1999–2000), where he deepened his scientific foundation. He then moved to the U.S. to pursue a Master’s in Biology at Temple University (2000–2003), followed by a Ph.D. in Molecular Biology from Kent State University (2004–2009), focusing on metabolic biology and gene regulation. This progression from general animal sciences to highly specialized molecular biology reflects a systematic and deep commitment to biomedical research. His strong academic preparation laid the foundation for a research career investigating how transcriptional regulators impact health and disease. Dr. Han’s training spans world-class institutions across both China and the United States, equipping him with diverse scientific perspectives and techniques.

Experience:

Dr. Shuxin Han has accumulated rich research and academic experience over nearly 30 years. His early career included a pivotal research assistant role at Peking University, followed by advanced training in biology and molecular biology at Temple and Kent State Universities. He completed prestigious postdoctoral training at Harvard Medical School (2009–2012) and Case Western Reserve University (2012–2015), where he later became a Senior Research Associate (2015–2019). He returned to China in 2019 as a Researcher at the University of Science and Technology of China First Affiliated Hospital, simultaneously engaging in academic duties at the university until 2023. Currently, he serves as a Professor and Academic Leader at Xinjiang University. Throughout his career, Dr. Han has built strong international collaborations, led research groups, and guided innovative projects in metabolic biology, demonstrating his leadership, research excellence, and academic mentorship capabilities.

Research Focus:

Dr. Shuxin Han’s research centers on the molecular regulation of metabolism, particularly focusing on the hepatobiliary and gastrointestinal systems. His work has elucidated the critical role of the Kruppel-like factor (KLF) family, especially KLF15, in controlling endobiotic and xenobiotic metabolism (EXM). These pathways govern how the body metabolizes both internal compounds and external substances like drugs. Dr. Han’s studies have shown that KLF15 acts as a master regulator, influencing drug resistance, liver injury, and metabolic homeostasis. His discoveries offer new insight into personalized medicine and treatment for metabolic disorders and drug-related toxicities. With numerous first-author and corresponding-author publications in journals such as Nature Metabolism, Nature Communications, and Drug Metabolism and Disposition, his work has significantly impacted both fundamental science and clinical applications. He is also active in peer-reviewing for top-tier journals and is recognized for his leadership in translational research.

Publications Top Notes:

  1. Unveiling KLF15 as the Key Regulator of Cyclosporine A Metabolism and Adverse EffectsDrug Metabolism and Disposition, 2025

  2. Distribution and Functional Significance of KLF15 in Mouse CerebellumMolecular Brain, 2025

  3. Personalized Statin Therapy: Targeting Metabolic ProcessesHeliyon, 2025

  4. Current Status and New Directions for Hepatocellular Carcinoma DiagnosisLiver Research, 2024

  5. KLF15-Cyp3a11 Axis Regulates Rifampicin-Induced Liver InjuryDrug Metabolism and Disposition, 2024

  6. Advancing Drug Delivery and Bioengineering in Liver ResearchBioengineering and Translational Medicine, 2024

  7. Advances in IL-7 Research on Tumor TherapyPharmaceuticals, 2024 (Co-author)

  8. Pathogenic Mechanisms in Alcoholic Liver DiseaseJournal of Translational Medicine, 2023

  9. Beta-Hydroxybutyrate Effects on iPSC-Derived Cardiac MyocytesBiomolecules, 2022

  10. Interactions Between Intestinal Flora and Bile AcidsInternational Journal of Molecular Sciences, 2022 (Corresponding author)

Conclusion:

In conclusion, Dr. Shuxin Han is a highly deserving candidate for the Best Researcher Award. His pioneering work on KLF15 and metabolic regulation has reshaped fundamental understanding in the field of hepatobiliary biology and pharmacology. His academic background, research productivity, international experience, and editorial service all reflect a well-rounded and impactful scientist. While there is room to increase clinical translation and international engagement, the depth, originality, and consistency of his research make him a strong contender for this recognition. Honoring Dr. Han with this award would acknowledge a career dedicated to scientific advancement with substantial implications for human health and drug therapy.

Jebunnahar Khandakar | Biological Sciences | Best Researcher Award

Dr. Jebunnahar Khandakar | Biological Sciences | Best Researcher Award

Dr. Jebunnahar Khandakar, Independent University, Bangladesh, Bangladesh

Dr. Jebunnahar Khandakar is an accomplished academic and researcher specializing in environmental science, plant physiology, and biotechnology. Currently serving as an Associate Professor in the Department of Life Sciences at Independent University, Bangladesh, she brings extensive expertise in sustainable agriculture and mushroom biotechnology. She earned her PhD from Nagasaki University, Japan, with a focus on plant-environment interactions and proteomics. Over her career, Dr. Khandakar has contributed significantly to research in mushroom cultivation, environmental sustainability, and food system innovations. Her work has been published in renowned journals, reflecting her commitment to developing practical, affordable, and eco-friendly solutions for agricultural improvement. She has also provided consultancy for global initiatives, including work with the UNCCD. Dr. Khandakar’s dedication to research and community impact makes her a strong candidate for recognition as a Best Researcher Award recipient.

Publication Profile: 

Google Scholar

Scopus

Orcid

Education:

Dr. Jebunnahar Khandakar’s educational background demonstrates a strong foundation in biotechnology and environmental science. She earned her Doctor of Philosophy (PhD) in September 2013 from Nagasaki University, Japan, where she focused on plant physiology and biotechnology, specifically analyzing stress responses and secondary metabolism in plants. Prior to that, she completed her MS in Biotechnology in July 2005 from Bangladesh Agricultural University with an excellent academic record (Grade A). Her MS research delved into mycelial growth and spawn production, forming the basis for her long-term interest in fungal biology. These degrees have equipped her with expertise in both applied and fundamental biosciences, particularly in sustainable crop production and biotechnological applications for food and environmental security. Her strong academic background supports her ongoing contributions to science through teaching, mentoring, and pioneering research projects.

Experience:

Dr. Jebunnahar Khandakar has nearly two decades of combined experience in academia and applied environmental science. She is currently an Associate Professor at Independent University, Bangladesh (IUB), where she has served since 2016, being promoted in September 2024. At IUB, she teaches and supervises students in plant biotechnology, environmental biology, and sustainable agriculture. Before her academic tenure, she served as a Junior Consultant for the United Nations Convention to Combat Desertification (UNCCD) at the Department of Environment in Dhaka, where she contributed to policy frameworks for sustainable land use and biodiversity conservation. Her role involved integrating scientific research into national strategies, further enriching her interdisciplinary understanding. Dr. Khandakar’s career trajectory highlights her ability to bridge academic knowledge with field applications, aligning science with real-world agricultural and environmental challenges.

Research Focus:

Dr. Khandakar’s research primarily centers on sustainable agriculture, environmental biotechnology, and fungal physiology. Her work spans optimizing substrates for mushroom cultivation, improving post-harvest shelf life, and exploring biowaste as cultivation media. She also explores molecular and physiological responses of medicinal plants like Hyoscyamus albus under abiotic stresses, including nutrient deficiencies and metal toxicity. Through proteomics and biochemistry, she investigates root signaling, riboflavin biosynthesis, and stress-induced metabolite changes. Recently, her research has shifted to low-cost, eco-friendly solutions for food production—developing nitrogen gas packaging for mushrooms and assessing market chains for semi-fermented fish. Her interdisciplinary approach blends biotechnology with environmental sustainability, aiming to improve nutrition, soil health, and farmer livelihoods. This diverse yet focused research portfolio underlines her impact and innovation in agricultural and life sciences, with clear contributions toward climate-smart and affordable food technologies.

Publications Top Notes: 

  1. Using spent mushroom substrate (SMS) as a casing boosted bacterial activity and enhanced the mineral profile of Calocybe indica.

  2. Deciphering the Role of Substrate C/N Ratio in Preventing Orange Mold Contamination in Mushroom Cultivation.

  3. Establishment of a Simple Single Spore Isolation Method for Gilled Mushroom Research.

  4. Optimizing Tea Waste as a Sustainable Substrate for Oyster Mushroom Cultivation.

  5. Packaging with Nitrogen Gas Enhanced Shelf-Life of Fresh Oyster Mushrooms.

  6. Exploring the Market Value Chain Dynamics of Chepa (Semi-Fermented Fish).

  7. Shelf-life Evaluation of Oyster Mushrooms using Different Packaging Materials and Storage Conditions.

  8. Survey on Technical Efficacy and Farmer Satisfaction for Onion Seed Production in Rajshahi.

  9. Extraction and Fractionation of Subproteome from Hyoscyamus albus Root Tips.

  10.  Reducing Pesticide Use in Cucumber Cultivation via Environment-Friendly Technology.

Conclusion:

Dr. Jebunnahar Khandakar is highly deserving of the Best Researcher Award. Her work is innovative, impactful, and highly aligned with real-world agricultural challenges—particularly in low-cost, sustainable food production methods and environmental biotechnology. She has demonstrated academic excellence, field application, and research leadership over the years, both nationally and internationally.