Assist. Prof. Dr. Insoon Chang | Tissue Engineering Regeneration | Research Excellence Award

Insoon Chang is a tenure-track Assistant Professor in Endodontics at a leading dental academic institution and a board-certified endodontist with a strong profile as a dual-trained clinician-scientist. Their work integrates clinical endodontics with translational and basic research, with primary expertise in regenerative endodontics, osteoimmunology, tissue regeneration, and inflammatory disease–associated healing. Research contributions span molecular biology, epigenetics, animal models, and clinically relevant systems, aiming to advance endogenous cell-mediated strategies for pulp–dentin complex regeneration. Completed studies have addressed epigenetic regulation of mesenchymal stem cells in osteoporosis and aging, as well as mechanisms of tumorigenesis and progression in head and neck squamous cell carcinoma. Ongoing research focuses on osteoimmune dysregulation in uncontrolled type II diabetes and innovative regenerative approaches using minced dental pulp transplantation. The scholarly output includes over 20 peer-reviewed publications in high-impact SCI/SCIE and Scopus-indexed journals across dentistry, cell biology, cancer research, and regenerative medicine. In addition to research, significant contributions are made to graduate and advanced clinical education, mentoring, program leadership, and interdisciplinary collaboration. Active national and international collaborations support translational and basic research efforts, positioning this work at the interface of clinical relevance and fundamental biological discovery.

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