Marija Gjorgoska | Cancer Cell Biology | Best Researcher Award

Mrs. Marija Gjorgoska | Cancer Cell Biology | Best Researcher Award

Mrs. Marija Gjorgoska | Institute of Biochemistry and Molecular Genetics, Faculty of Medicine, University of Ljubljana | Slovenia

Marija Gjorgoska is a dedicated biomedical researcher and teaching assistant at the Faculty of Medicine, University of Ljubljana, Slovenia. With a strong background in biochemistry, molecular biology, and bioinformatics, she has contributed significantly to cancer research, focusing on steroid hormone signaling in gynecological cancers. Her scientific work combines analytical expertise in LC-MS/MS with a solid foundation in molecular biology and statistical analysis using R programming. Marija is passionate about advancing clinical diagnostics and cancer treatment through high-precision biomolecular profiling. Her academic journey reflects international exposure through internships in the UK and Macedonia. She is known for her collaborative spirit and commitment to scientific rigor, which has led to multiple high-impact publications. Marija continues to mentor students and contribute to the academic community through her teaching role, making her a rising figure in molecular oncology research.

publication profile:

scopus

Strengths:

  1. High Research Productivity 📈
    Marija Gjorgoska has authored or co-authored 10 peer-reviewed publications in high-impact journals such as Progress in Lipid Research (IF 14.0), Trends in Endocrinology and Metabolism (IF 11.4), and Cancers. Her work shows consistent scientific output, often with first or shared first authorship.

  2. Cutting-Edge Technical Expertise 🔬
    She demonstrates advanced proficiency in LC-MS/MS method development, multi-steroid profiling, and bioinformatics (R programming). This makes her an expert in translational hormone research and biomarker discovery.

  3. Clinical Relevance and Innovation ⚕️
    Her research addresses urgent clinical challenges like endometrial cancer diagnosis and ovarian cancer drug resistance, applying modern analytical techniques combined with machine learning, which positions her at the forefront of personalized medicine.

  4. Recognition and Collaboration 🤝
    She has been awarded prestigious grants (e.g., Society of Endocrinology, UK), collaborated internationally (UK, Macedonia), and contributes to academia as a teaching assistant—all signs of an emerging research leader.

  5. Interdisciplinary Impact 🌐
    Marija effectively integrates molecular biology, biochemistry, analytical chemistry, and computational biology—indicative of her versatility and broad scientific impact.

Areas for Improvement:

  1. Independent Research Leadership
    While she has made substantial contributions as a junior and co-investigator, future work could benefit from establishing herself as a principal investigator or project leader, including securing her own research funding.

  2. Diversification of Research Themes
    Her focus has been predominantly on hormone-related cancers. Expanding into other disease models or mechanisms could broaden her impact and create new collaborative opportunities.

  3. Public Engagement and Outreach
    Enhancing her visibility through conference presentations, science communication, or community health initiatives would further solidify her standing as a leader and advocate for biomedical research.

Education :

Marija Gjorgoska is currently enrolled in a doctoral program in Biomedicine, specializing in Biochemistry and Molecular Biology at the University of Ljubljana. Her academic foundation includes a Master’s degree in Molecular Biology (2018–2021) from the same university, completed with an outstanding GPA of 9.52/10. She also gained international experience through a short-term internship at the University of Birmingham, UK, in 2023, focusing on advanced LC-MS/MS techniques for clinical sample analysis. Earlier in her academic career, she completed a long-term internship at the Research Center for Genetic Engineering and Biotechnology in Skopje, Macedonia (2017), where she worked on genetic diagnostics involving haemoglobinopathies, HPV, HBV, and HCV detection. Her education has consistently emphasized both theoretical knowledge and hands-on laboratory skills, particularly in analytical chemistry, molecular biology, and bioinformatics, all of which shape her current research endeavors in cancer diagnostics and hormonal regulation.

Experience:

Marija Gjorgoska has been actively engaged in research since 2020 as a Research Assistant at the Institute of Biochemistry and Molecular Genetics, Faculty of Medicine, University of Ljubljana. Her core responsibilities include developing and validating LC-MS/MS analytical methods, conducting proteomic and genetic analyses of cancer tissues, and performing bioinformatic evaluations using R programming. In October 2024, she also began serving as a Teaching Assistant for the course “Principles of Biochemistry,” demonstrating her commitment to education and mentorship. Marija’s prior internships have equipped her with valuable skills in prenatal and infectious disease diagnostics. Her research contributions span experimental planning, scientific writing, and instrument maintenance, establishing her as a versatile scientist. Her collaborative projects with international researchers and clinicians further underline her strength in translational biomedical research. This combination of teaching, laboratory, and analytical expertise supports her growing influence in molecular oncology.

Awards and Honors:

Marija Gjorgoska has been recognized for both academic and research excellence. In 2023, she was awarded the Practical Skills Grant by the Society of Endocrinology, UK, enabling her to undergo advanced training in LC-MS/MS at the University of Birmingham. Earlier, in 2021, she received the Krka Recognition with Special Praise for her Master’s thesis, highlighting her early promise as a researcher in molecular biology. Her scientific publications have appeared in top-tier journals such as Progress in Lipid Research and Trends in Endocrinology and Metabolism, some with impact factors exceeding 14.0. Notably, she earned shared first co-authorship in Methods in Enzymology for her work on enzymatic assay development. These accolades reflect her technical excellence, originality, and scientific contributions in the field of steroid metabolism and gynecological cancers. Marija’s achievements distinguish her as a young researcher with significant impact and high potential for further contributions to science and medicine.

Research Focus :

Marija Gjorgoska’s research focuses on the role of steroid hormones in the development and progression of gynecological cancers, particularly endometrial and ovarian cancers. Her work integrates analytical chemistry (LC-MS/MS), bioinformatics, and molecular biology to uncover diagnostic and prognostic biomarkers. She has developed multi-steroid profiling techniques to differentiate between normal and cancerous tissues, aiding early diagnosis. Marija’s studies also address the pre-receptor regulation of androgenic and estrogenic hormones, exploring their signaling dynamics at the tissue level. Using tools such as Mendelian randomization, she investigates genetic influences on hormone-related disease risk. Her interdisciplinary approach combines advanced mass spectrometry, statistical modeling, and clinical collaboration to translate bench science into meaningful medical applications. Through high-impact publications, she contributes to understanding hormone metabolism in cancer microenvironments, with the goal of informing targeted therapies and overcoming drug resistance. Her work is critical for advancing personalized medicine in hormone-driven malignancies.

Publications Top Notes:

  1. 📘 From fallopian tube epithelium to high-grade serous ovarian cancer: A single-cell resolution review of sex steroid hormone signalingProgress in Lipid Research, 2024

  2. 📘 Integration of androgen hormones in endometrial cancer biologyTrends in Endocrinology and Metabolism, 2022

  3. 📘 Steroid sulfatase and sulfotransferases in gynecological cancers: current status and perspectivesEssays in Biochemistry, 2024

  4. 📘 Estrogens and the Schrödinger’s cat in the ovarian tumor microenvironmentCancers, 2021

  5. 📘 Multi-Steroid Profiling and Machine Learning Reveal Androgens as Biomarkers for Endometrial CancerCancers, 2025

  6. 📘 Simultaneous measurement of 17 endogenous steroid hormones by LC-MS/MSJ. of Steroid Biochemistry and Molecular Biology, 2024

  7. 📘 11-oxyandrogens in normal vs. cancerous endometriumFrontiers in Endocrinology, 2024

  8. 📘 Targeting estrogen metabolism to overcome platinum resistance in ovarian cancerBiomedicine & Pharmacotherapy, 2024

  9. 📘 Effect of androgens on risk of endometriosis sub-phenotypes and ovarian neoplasmsJ. of Steroid Biochemistry and Molecular Biology, 2024

  10. 📘 Enzymatic assays for 17β-HSD types 1 and 2 using mass spectrometryMethods in Enzymology, 2023

Conclusion:

Marija Gjorgoska is a highly promising early-career researcher with a strong and growing international publication record, deep technical expertise in analytical biochemistry, and a clear focus on clinically relevant research. Her integration of hormonal pathway analysis with state-of-the-art analytical methods has already contributed valuable insights to the field of gynecological oncology. She has the academic rigor, curiosity, and collaborative drive essential for impactful science.

In my opinion, she is a highly suitable candidate for the Best Researcher Award. Continued mentorship and support toward independent research leadership will elevate her even further in the years to come.

Tao Zhang | Cancer Cell Biology | Best Researcher Award

Prof. Tao Zhang | Cancer Cell Biology | Best Researcher Award

Prof. Tao Zhang, South China Normal University, China

Dr. Tao Zhang is a distinguished Professor at the College of Biophotonics, South China Normal University, where he has been advancing the frontiers of chemical biology and phototheranostics. With a keen focus on developing innovative optical probes and imaging techniques for tumor diagnosis and treatment, Dr. Zhang has made significant contributions to the field of lanthanide chemistry and biomedical imaging. His academic journey spans from Ningbo University (MPhil) to earning his Ph.D. in Chemistry from Hong Kong Baptist University. As a corresponding author on numerous high-impact publications and a recipient of multiple prestigious provincial awards, Dr. Zhang has earned recognition for both research excellence and academic leadership. He is actively involved in interdisciplinary collaborations, producing over 40 peer-reviewed publications in journals such as Nature Communications, PNAS, JACS, and Advanced Science. His ongoing work addresses critical challenges in imaging-guided therapies for cancer under hypoxic and complex microenvironment conditions.

Publication Profile: 

Scopus

✅ Strengths for the Award:

  1. 📈 Outstanding Research Output
    Dr. Zhang has published over 40 peer-reviewed articles in top-tier journals such as Nature Communications, Advanced Science, JACS, ACS Nano, and PNAS. These works cover cutting-edge topics in photodynamic therapy, tumor imaging, and nanotechnology—key areas in modern biomedical research.

  2. 🧪 Innovation in Biomedical Chemistry
    He has demonstrated consistent originality by designing oxygen-independent Type I pro-photosensitizers, reversible ratiometric photoacoustic probes, and multimodal imaging nanoplatforms, all of which target real-world challenges in hypoxic tumor environments.

  3. 🌏 National Recognition
    His research excellence has been recognized by prestigious awards such as the Special Support Program for Young Top-notch Talents of Guangdong Province and the Pearl River Science and Technology Rising Star of Guangzhou, both in 2018.

  4. 🎯 Multidisciplinary Expertise
    With a strong background in lanthanide chemistry, chemical biology, and optical imaging, Dr. Zhang successfully bridges multiple fields, demonstrating a holistic approach to solving biomedical challenges.

  5. 📚 Leadership Role
    As a corresponding author on many publications, he plays a leading role in both research direction and execution. His progression from Assistant to Full Professor between 2014 and 2021 further reflects his capability as a research leader.

🛠️ Areas for Improvement:

  1. 🌐 International Collaborations & Visibility
    While Dr. Zhang has co-authored with international researchers, expanding his global collaborative network through joint grants, keynote talks, or leadership in international consortia could further enhance his profile.

  2. 👨‍🏫 Public Outreach & Technology Transfer
    Increasing efforts in public science communication, patenting innovations, or transitioning lab technologies into clinical trials could strengthen his case for broader societal impact.

  3. 📢 Social & Digital Engagement
    A higher digital or social media presence (e.g., ResearchGate, Google Scholar metrics, professional website updates) would make his research more visible to the global community and potential collaborators.

🎓 Education:

Dr. Tao Zhang embarked on his academic career with an MPhil in Inorganic Chemistry from Ningbo University (2006–2009), where he conducted research under Professor Hongze Liang. He furthered his education by pursuing a Ph.D. in Chemistry at Hong Kong Baptist University (2009–2013), mentored by Professors Wai-Kwok Wong and Ka-Leung Wong. His doctoral research focused on lanthanide coordination chemistry and bioimaging, setting a strong foundation for his future innovations in photodynamic therapy and tumor diagnostics. These formative years not only shaped his technical expertise in spectroscopy and nanomaterials but also cultivated a rigorous research ethic that has carried through his academic trajectory. His education was marked by cross-disciplinary training in synthetic chemistry, photophysics, and biological applications, providing him with a broad and robust skill set that continues to support his ongoing exploration in chemical biology and optical probes for clinical imaging and therapeutic interventions.

💼 Experience:

Dr. Zhang’s academic career at South China Normal University’s College of Biophotonics began in 2014 as an Assistant Professor. He was promoted to Associate Professor in 2017 and then to full Professor in 2021. Throughout his academic appointments, Dr. Zhang has led innovative research in tumor imaging, photothermal therapy, and optical diagnostics, establishing a productive research group known for creative nanoprobe design and translational research. His lab has secured multiple research grants and frequently collaborates with international researchers, combining chemical innovation with biomedical applications. Dr. Zhang has mentored graduate students and postdocs, many of whom have gone on to prestigious research positions. His steady academic progression reflects both his research productivity and leadership in the field of phototheranostics. Over the years, his expertise has positioned him at the forefront of integrating nanotechnology and chemistry into next-generation diagnostic and therapeutic platforms for treating cancer and understanding tumor microenvironments.

🏆 Awards and Honors:

Dr. Tao Zhang has received multiple prestigious awards that underscore his exceptional research contributions and scientific leadership. In 2018, he was honored with the Special Support Program for Young Top-notch Talents of Guangdong Province, recognizing his pioneering work in optical molecular probes for cancer imaging. That same year, he also received the Pearl River Science and Technology Rising Star of Guangzhou, further validating the impact and innovation of his interdisciplinary research in chemical biology. These accolades highlight his rising prominence as a researcher capable of translating basic chemical discoveries into practical medical technologies. He is consistently invited to contribute as a corresponding author in top-tier journals, reflecting the high regard his peers have for his scientific insight and rigor. These honors not only reflect personal achievement but also enhance the prestige of the College of Biophotonics at South China Normal University, where he continues to lead cutting-edge research.

🔍 Research Focus:

Dr. Tao Zhang’s research focuses on the convergence of Chemical Biology, Lanthanide Chemistry, and Optical Imaging Technologies for cancer diagnosis and treatment. His main interest lies in developing smart, light-activated nanomaterials and photosensitizers that enable precise imaging and phototherapy, particularly in hypoxic tumor microenvironments. His team is advancing Type I photodynamic therapy agents and oxygen-independent systems, addressing critical limitations in current cancer treatment modalities. Another core area of his research is the creation of upconversion nanoparticles and ratiometric probes for real-time, non-invasive imaging—capable of dual-modality functionality (fluorescence and photoacoustic). Leveraging lanthanide chemistry, Dr. Zhang also contributes to MRI contrast agent innovation and multimodal diagnostics. His cross-disciplinary work integrates synthetic chemistry, molecular design, and biological application, offering new avenues for theranostics. His cutting-edge research is published in leading journals, pushing the boundaries of tumor imaging, molecular sensing, and personalized cancer therapy with minimal invasiveness and enhanced specificity.

📚 Publications Top Notes:

  1. 🧬 Totally Caged Type I Pro-Photosensitizer for Oxygen-Independent Synergistic Phototherapy of Hypoxic TumorsAdvanced Science, 2024

  2. 🔁 Switching the NIR Upconversion of Nanoparticles for Orthogonal Activation of Photoacoustic Imaging and PhototherapyNature Communications, 2022

  3. 🧪 Dynamic-Reversible Photoacoustic Probe for Continuous Ratiometric Sensing and Imaging of Redox Status In VivoJACS, 2019

  4. 🎯 In Vivo Imaging-Guided Photothermal/Photoacoustic Synergistic Therapy with Tumor-Targeting NanoparticlesACS Nano, 2017

  5. 💥 In Vivo Selective Cancer-Tracking Gadolinium Eradicator as New-Generation Photodynamic Therapy AgentPNAS, 2014

  6. 🧫 ROS-Catalytic Self-Amplifying Benzothiophenazine-Based Photosensitive Conjugates for Photodynamic-Immuno TherapyBiomaterials, 2025

  7. 🧬 A Self-Catalytic UCNP-Based Nanomachine for Highly Sensitive Detection of CTCsBiosensors and Bioelectronics, 2025

  8. 🔍 An AND-Gate Photoacoustic Probe for Cys and H2S Precise Photoacoustic Sensing in TumorsAnal. Chem., 2024

  9. 🎨 Single Side-Chain-Modulatory of Hemicyanine for Fluorescence and Photoacoustic Dual-Modality ImagingSmall Methods, 2024

  10. 🌫️ High-Contrast Photoacoustic Imaging of Localized Cysteine in Breast CancerChem. Eur. J., 2024

🧾 Conclusion:

Dr. Tao Zhang is highly suitable for the Best Researcher Award due to his exceptional scholarly output, innovative biomedical applications, and proven academic leadership. His work addresses some of the most critical challenges in cancer diagnostics and therapy using chemical tools and photonic technology.