Moara Lemos | Cell Structure Analysis | Best Researcher Award

Dr. Moara Lemos | Cell Structure Analysis | Best Researcher Award

Dr. Moara Lemos, UFRJ/CENABIO, Brazil

Dr. Moara Lemos is a Brazilian parasitologist and structural biologist known for her expertise in protozoology, especially focusing on trypanosomatids. Born in Carmo do Rio Claro, Brazil, she earned her PhD in Microbiology from the Federal University of Rio de Janeiro (UFRJ). Her work bridges advanced imaging technologies, such as cryo-electron tomography, with molecular parasitology, exploring host-parasite interactions in fish and amphibians. Currently based at Institut Pasteur and UFRJ, she leads cutting-edge projects in cellular ultrastructure, nanobiotechnology, and the molecular characterization of parasites. She has received multiple research scholarships and international recognition through high-impact publications and awards. A highly collaborative scientist, Dr. Lemos has contributed significantly to parasitology, cryo-microscopy, and biomedicine, making her a strong candidate for the Best Researcher Award.

Publication Profile: 

Orcid

✅ Strengths for the Award:

  1. Extensive Expertise in Parasitology and Cell Biology

    • Specialized in protozoology, with deep research in Trypanosoma species affecting both aquatic vertebrates and humans.

    • Combines taxonomy, ultrastructure, phylogeny, and host-parasite interactions, contributing significantly to neglected areas in parasitology.

  2. Cutting-edge Methodological Proficiency

    • Strong command over electron microscopy, including cryo-electron tomography, FIB-SEM, and correlative light and electron microscopy (CLEM).

    • Her techniques are pivotal in advancing the 3D visualization of cellular and viral structures, which is particularly impactful in infectious disease research.

  3. Translational Research Impact

    • Active participation in COVID-19-related structural virology, aiming to guide vaccine and therapeutic development.

    • Current projects focus on flagellar biogenesis, nanobiomaterials, and telepathology, integrating basic science with clinical relevance.

  4. Collaborative and International Research Network

    • Collaboration with prestigious institutions such as the Institut Pasteur, João Lobo Antunes Institute, EMBO, and CBPF.

    • Involved in multidisciplinary teams with researchers like Dorit Hanein and Philippe Bastin, increasing the credibility and reach of her research.

  5. Recognized Scientific Output

    • Publications in high-impact journals like Nature Communications, Journal of Cell Biology, *

🛠️ Areas for Improvement:

While her qualifications are substantial, a few areas could further elevate her candidacy:

  1. Greater Independent Leadership on High-Profile Projects

    • While she is a co-author on several collaborative works, leading more first-author or corresponding-author publications in top-tier journals would further establish her scientific independence.

  2. Increased Outreach or Policy Engagement

    • Expanding her influence beyond academic research—e.g., contributing to national or international policy on parasitic diseases, public health, or biodiversity conservation—could broaden impact.

  3. Clearer Documentation of Teaching/Mentorship Impact

    • While the CV lists student supervision (MSc, PhD), a dedicated summary on mentorship outcomes (e.g., students’ careers, theses supervised) would strengthen the case.

  4. Visibility in International Conferences as Speaker

    • More keynote/plenary presentations or chairing roles at major international meetings would reinforce her leadership in the field.

🎓 Education:

Dr. Lemos holds a Bachelor’s degree in Biological Sciences from the Federal University of Juiz de Fora (UFJF), where she also completed a Master’s degree in Zoology. She earned her PhD in Science (Microbiology) from the Federal University of Rio de Janeiro (UFRJ), with a dissertation on the taxonomy and host-parasite interactions of trypanosomes in Brazilian fish. Her postgraduate journey continued with multiple postdoctoral fellowships at institutions like the Institut Pasteur (France), CBPF (Brazil), and UFRJ, specializing in parasitology, biotechnology, and cryo-electron microscopy. She also pursued extensive complementary training in microscopy, cryo-ET, and molecular biology through EMBO and SBMM courses. Her education reflects a strong interdisciplinary foundation combining zoology, microbiology, biotechnology, and imaging technologies—crucial for investigating infectious diseases at a cellular and molecular level.

🎓 Education:

Dr. Lemos holds a Bachelor’s degree in Biological Sciences from the Federal University of Juiz de Fora (UFJF), where she also completed a Master’s degree in Zoology. She earned her PhD in Science (Microbiology) from the Federal University of Rio de Janeiro (UFRJ), with a dissertation on the taxonomy and host-parasite interactions of trypanosomes in Brazilian fish. Her postgraduate journey continued with multiple postdoctoral fellowships at institutions like the Institut Pasteur (France), CBPF (Brazil), and UFRJ, specializing in parasitology, biotechnology, and cryo-electron microscopy. She also pursued extensive complementary training in microscopy, cryo-ET, and molecular biology through EMBO and SBMM courses. Her education reflects a strong interdisciplinary foundation combining zoology, microbiology, biotechnology, and imaging technologies—crucial for investigating infectious diseases at a cellular and molecular level.

🏅 Awards and Honors:

Dr. Moara Lemos has received numerous accolades throughout her career. She won the Best Poster Presentation at the Institut Pasteur and the VIII International Symposium of Fish Parasites, along with the Best Oral Presentation Award at Sembio 2007. She was also recognized at the IV Annual Meeting of the National Institute of Science and Technology in Structural Biology and Bioimaging (INBEB). She has been a scholarship holder from multiple funding bodies, including CNPq, CAPES, FAPERJ, and FAPEMIG, for her postgraduate and postdoctoral research. In addition, she contributed to groundbreaking studies published in Nature Communications, Journal of Cell Biology, and American Journal of Human Genetics, earning visibility in high-impact journals. These honors highlight her impactful contributions to biomedical research, particularly in parasitology and cryo-structural biology.

🔬 Research Focus:

Dr. Lemos focuses on parasitic protozoa, especially trypanosomes, examining their ultrastructure, taxonomy, host-parasite dynamics, and intraflagellar transport mechanisms. She employs advanced imaging technologies, including cryo-electron tomography, to study the 3D cellular architecture of infectious organisms like Trypanosoma cruzi. Her research expands to the SARS-CoV-2 virus, developing cryo-microscopy workflows to analyze virus-antibody interactions. She also explores nanobiomaterials’ interactions with eukaryotic cells, combining cell biology, structural biology, and electron microscopy. Current projects include implementing telemicroscopy in Brazil’s public health system (SUS) and developing AI tools for pathology imaging. Her goal is not only to advance scientific knowledge but also to translate findings into public health and ecological conservation strategies. Dr. Lemos’ integrative and technological approach to biology makes her research highly innovative and socially relevant.

📚 Publications Top Notes:

  1. 📘 Advances, challenges, and applications of cryo‐electron tomography workflows for three‐dimensional cellular imaging of infectious pathogensJournal of Microscopy (2025)

  2. 🧪 Novel ACE2 nanoparticles universally block SARS-CoV-2 variants in the human respiratory tractbioRxiv (2022)

  3. 🔬 Morphological control enables nanometer-scale dissection of cell-cell signaling complexesNature Communications (2022)

  4. 🧬 Timing and original features of flagellum assembly in trypanosomes during development in the tsetse flyParasites & Vectors (2020)

  5. 🐸 Caracterização morfológica e morfométrica dos tripanossomas de anuros do Centro-Oeste brasileiroRevista Brasileira de Zoociências (2019)

  6. 🧫 Biallelic Mutations in LRRC56…Cause Mucociliary Clearance and Laterality DefectsAmerican Journal of Human Genetics (2018)

  7. 🧭 Bidirectional intraflagellar transport is restricted to two sets of microtubule doublets in the trypanosome flagellumJournal of Cell Biology (2018)

  8. 📗 Contribuição ao estudo da biologia dos Tripanossomas de Anuros neotropicaisThesis, UFJF (2017)

🏁 Conclusion: 

Dr. Moara Lemos demonstrates a rare combination of technical excellence, innovative research, international collaboration, and consistent productivity in fields that have both scientific importance and global health relevance. Her research in trypanosome biology, electron microscopy, and pathogen-cell interaction is critical for both basic science and applied biomedical research.

Sona Jain | Protein structural analysis | Best Researcher Award

Assist. Prof. Dr. Sona Jain | Protein structural analysis | Best Researcher Award

Assist. Prof. Dr. Sona Jain , Federal University of Sergipe , Brazil

Dr. Sona Arun Jain is a distinguished professor and researcher at the Federal University of Sergipe, Brazil, with extensive expertise in microbial drug resistance, genetic engineering, and biotechnological applications. She has made significant contributions to the fields of molecular biology, genetics, and natural product discovery. With over two decades of academic and research experience, Dr. Jain has conducted pioneering work on the cloning and functional analysis of genes in Fusarium oxysporum and other microbial organisms. She has held various prominent academic positions across Brazil, Japan, Canada, and the USA, and supervised numerous students at different academic levels. Her research interests focus on developing novel antimicrobial, biopesticide, and probiotic compounds, as well as exploring alternative methods to combat microbial resistance. Her extensive list of publications includes over 70 journal articles and 46 abstracts, highlighting her profound impact in the field.

Publication Profile:

Google Scholar

Strengths for the Award:

  1. Extensive Academic and Research Experience:
    • Dr. Jain has held significant academic positions, currently serving as a professor and researcher at the Federal University of Sergipe, Brazil, and having extensive prior experience in various universities and research institutions.
    • This includes working as a postdoctoral fellow in prominent research centers, such as the Brazilian Agricultural Research Corporation (Embrapa), and the University of Waterloo, Canada, and the University of Illinois, USA.
  2. Wide Range of Research Interests:
    • Dr. Jain’s research spans several critical and impactful fields including microbial drug resistance, natural product discovery (antimicrobials, biopesticides, probiotics), and fungal genetics, which are highly relevant in addressing global health challenges.
    • Specific focus on microbial drug resistance is crucial in the face of rising antibiotic resistance.
  3. Research Leadership and Student Supervision:
    • Dr. Jain has supervised several doctoral students (5), master’s students (12), and undergraduate research mentorship programs (12), demonstrating an exceptional track record in academic leadership and mentoring.
    • Currently, Dr. Jain is supervising a postdoctoral fellow, 2 doctoral students, and 2 master’s students, highlighting ongoing contributions to the next generation of scientists.
  4. Strong Publication Record:
    • Dr. Jain has contributed to 70 articles in refereed journals and 46 abstracts in congress proceedings, showcasing a strong and continuous output in high-impact scientific publications.
    • Publications in top-tier journals, such as Biomolecules, Critical Reviews in Microbiology, and Journal of Applied Oral Science, reinforce the quality and impact of the research.
  5. International Collaboration:
    • Participation in various international research projects with collaborators from multiple countries (Japan, Canada, USA, Brazil) demonstrates a collaborative mindset and the ability to work across borders.
    • Collaborative studies on microbial biopesticides, leishmaniasis, and antimicrobial resistance are all highly relevant.
  6. Innovative Research in Drug Resistance and Treatment:
    • Dr. Jain has focused on developing novel solutions for drug-resistant pathogens, such as Bacillus thuringiensis, nisin variants, and leishmaniasis treatment, indicating a strong commitment to improving public health through scientific research.
    • Contributions in drug delivery systems, biosensors, and antimicrobial peptides (e.g., nisin) reflect the ability to innovate in biomedical applications.
  7. Research Funding and Recognition:
    • Dr. Jain has been funded by various prestigious research organizations, including the Brazilian Coordination for the Improvement of Higher Education Personnel (CAPES), the Brazilian Agricultural Research Corporation (Embrapa), and the Japanese Ministry of Education, Culture, Sports, Science and Technology (MEXT).
    • This recognition and support underline the credibility and importance of Dr. Jain’s research contributions.

Areas for Improvement:

  1. Broader Public Engagement:
    • While Dr. Jain’s scientific publications are numerous and impactful, there seems to be limited focus on outreach to the general public, policymakers, or non-scientific stakeholders. Engaging with the broader public through popular science, media, and policy advocacy could help extend the influence of the research.
    • Further dissemination of findings in easily accessible formats (e.g., popular articles, talks, webinars) could contribute to greater societal impact.
  2. Diversity in Research Topics:
    • While Dr. Jain has worked in a variety of topics within microbiology and drug resistance, expanding research into broader areas (e.g., environmental microbiology, climate change, etc.) could diversify the research portfolio.
    • Collaboration with researchers from other scientific disciplines, such as environmental science or computational biology, could bring new dimensions to current research topics.
  3. Increased Involvement in Industry Collaboration:
    • Dr. Jain has an academic background but could increase collaboration with the biotechnology or pharmaceutical industry to translate research findings into real-world applications, particularly in areas such as biopesticides, antimicrobial drug discovery, and vaccines.
  4. Increased Research Impact Measurement:
    • While Dr. Jain has an extensive publication record, there could be a greater emphasis on research impact metrics such as citation indices, patent filings, and real-world application of research. A stronger focus on translating discoveries into tangible products or services may enhance visibility.

Education:

Dr. Sona Arun Jain holds a Ph.D. in Genetic Engineering from Ehime University, Japan (2003), where she conducted groundbreaking research on G protein subunit genes in Fusarium oxysporum under the mentorship of Prof. Dr. Renkichi Takata. This work involved the cloning and functional analysis of these genes through targeted gene disruption. She also earned an M.Ag. (Applied Bioresource Science) from Ehime University (2000), where she focused on isolating nonpathogenic strains of Fusarium oxysporum. Her studies were supported by the Japanese Ministry of Education, Culture, Sports, Science, and Technology (MEXT). Additionally, Dr. Jain completed a Postgraduate Diploma in Public Relations from the University of Mumbai, India (1996), and a B.Sc. in Microbiology from Sophia College, University of Mumbai, India (1995). Her diverse academic background has empowered her to integrate scientific and communicative strategies in her research and teaching.

Experience:

Dr. Sona Arun Jain has an illustrious academic and research career spanning over 20 years, with key positions at top institutions worldwide. Since 2024, she has been a Professor and Researcher at the Federal University of Sergipe, Brazil. Prior to this, she served as a Professor and Researcher at Tiradentes University (2019-2023) and a Visiting Researcher at renowned institutions such as the University of Waterloo, Canada, and the University of Illinois at Urbana-Champaign, USA. Her research experience also includes significant contributions at the Brazilian Agricultural Research Corporation (Embrapa), where she worked on the development of ELISA tests and the identification of cotton diseases. As a visiting researcher and research fellow, Dr. Jain has made notable advancements in molecular biology, antimicrobial research, and biotechnological applications. Throughout her career, she has mentored and supervised numerous doctoral, master’s, and undergraduate students, shaping the next generation of scientists.

Research Focus:

Dr. Sona Arun Jain’s research focuses on microbial drug resistance, natural product discovery, and the development of biotechnological applications in various fields, including health and agriculture. Her work includes the exploration of novel antimicrobials, biopesticides, and probiotics to combat emerging threats from multi-drug resistant microbes. She has also worked extensively on identifying microbial strains with potential medicinal properties and examining their applications in treating diseases like leishmaniasis. Dr. Jain is deeply involved in understanding microbial genetics, particularly through the study of G proteins and their role in pathogenicity. Her work on Bacillus thuringiensis and Cry toxins exemplifies her efforts to find eco-friendly solutions for pest control. Moreover, she focuses on the biosynthesis of bioactive compounds from microorganisms and their use in drug delivery systems. With a strong foundation in molecular biology and microbiology, her research aims to tackle pressing global health and environmental challenges.

Publications Top Notes:

  1. Use of agro-industrial bio-waste for Bacillus thuringiensis growth 🌾🐛
  2. Nisin variants: what makes them different and unique? 🧀🔬
  3. Brazilian essential oils with leishmanicidal activity 🌿💉
  4. Biosensor-integrated drug delivery systems for biomedical applications 🧪💡
  5. Chromatographic profiles of Bacillus sp. from Brazilian Mangroves 🌿🧫
  6. Bacillus thuringiensis: from biopesticides to anticancer agents 🦠💊
  7. Volatile nitrogenous compounds from bacteria: novel bioactive sources 🦠🔬
  8. Antileishmanial compounds from microbial metabolites 🦠💀
  9. Nisin resistance in Gram-positive bacteria 🦠🔒
  10. Biological aspects of entomopathogenic fungus Aschersonia 🍄🦠
  11. Multidrug-resistant bacteria and control methods overview 🦠💉
  12. G protein α subunit disruption in Fusarium oxysporum 🔬🍄

Conclusion:

Dr. Sona Arun Jain stands out as a highly accomplished researcher and educator with a solid track record in microbial drug resistance, antimicrobial discovery, and applied biosciences. Her extensive academic career, impressive publication record, research leadership, and international collaborations position her as an exceptional candidate for the Research for Best Researcher Award.

Her contributions to advancing scientific knowledge, especially in drug resistance, biopesticides, and antimicrobial peptides, make her an invaluable asset to the scientific community. Additionally, her passion for mentoring students and supervising young researchers ensures that her impact will continue to resonate for years to come.

With slight improvements in public engagement, cross-disciplinary research, and industry collaboration, Dr. Jain’s career trajectory could become even more influential in shaping the future of scientific research in her fields of expertise. Therefore, Dr. Jain is strongly recommended for this prestigious award.