Kewalin Inthanon | Lipid Signaling Biology | Best Researcher Award

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Assist. Prof. Dr. Kewalin Inthanon | Lipid Signaling Biology | Best Researcher Award

Assist. Prof. Dr. Kewalin Inthanon , Thammasat University , Thailand

Dr. Kewalin Inthanon is an Assistant Professor at Thammasat University’s Faculty of Science and Technology in Lampang, Thailand. With a robust academic background, he holds a Ph.D. in Biology from Chiang Mai University and an M.Phil. in Clinical Neuroscience from the University of Cambridge. His expertise is in biotechnology, biochemistry, and the application of natural products and biomaterials to cellular and molecular research. Dr. Inthanon has contributed extensively to the study of cell cultures, oxidative stress, cellular senescence, and the effects of plant extracts, drugs, and biomaterials on cellular functions. His academic career is complemented by numerous research publications and successful research projects focusing on advancing the therapeutic potential of natural compounds and biocompatible materials. As a recognized researcher with notable expertise, he has become an influential figure in the fields of cellular biology and biotechnology.

Publication Profile: 

Orcid

Strengths for the Award

  1. Expertise and Research Focus: Dr. Inthanon has specialized expertise in biochemistry, biotechnology, and the integration of natural products with biomaterials. His research into cytotoxicity, oxidative stress, cellular senescence, and cellular responses to plant extracts, drugs, and biomaterials demonstrates a profound commitment to addressing both fundamental and applied scientific problems. His focus on stem cells, cancer cells, and natural compounds, particularly in the context of human cell cultures, is highly relevant to cutting-edge biotechnology.

  2. Publication Record: Dr. Inthanon’s extensive publication record includes high-impact journal articles in reputable journals like Scientific Reports, Chemistry of Natural Compounds, and Biocatalysis and Agricultural Biotechnology. His papers are well-cited, and he has co-authored several influential studies on the pharmacological and therapeutic properties of plant-derived compounds and biomaterials.

  3. Academic and Research Leadership: As an academic lecturer at Thammasat University and a postdoctoral researcher at Chiang Mai University, Dr. Inthanon demonstrates leadership in guiding the next generation of scientists. His involvement in multiple research projects and the administration of a major phytochemical analysis and bioactivity study on Dillenia indica L. shows his proactive approach to research development.

  4. Innovation and Collaborative Approach: Dr. Inthanon is an excellent collaborator, as seen in his contributions to multi-author publications and his involvement in collaborative projects across different research fields, such as bioengineering, cell culture systems, and plant-derived natural products. This collaborative nature reflects his ability to contribute effectively to both local and international scientific communities.

  5. Peer Review and Recognition: His participation as a peer reviewer for journals such as Food Science & Nutrition and Exploration of BioMat-X further underscores his credibility and recognition within the research community.

Areas for Improvement

  1. Expansion of Interdisciplinary Research: While Dr. Inthanon has done well in integrating natural products with biomaterials and biotechnology, further expansion into interdisciplinary research involving fields such as nanotechnology, synthetic biology, or environmental biotechnology could open up new avenues for innovation.

  2. Increased Public Outreach: Engaging in more public outreach or science communication could help Dr. Inthanon bridge the gap between academic research and broader societal impacts. This could involve more public lectures, writing for popular science outlets, or working with non-academic stakeholders (such as the pharmaceutical industry) to translate research into practical applications.

  3. Development of Commercializable Products: While Dr. Inthanon has demonstrated strong research on natural compounds and biomaterials, focusing on the development of commercializable biotechnological products, such as drugs or health supplements, could further highlight his potential for impactful, real-world applications.

Education:

Dr. Kewalin Inthanon completed his Bachelor of Science (BSc) and Master of Science (MSc) in Biology at Chiang Mai University, Thailand, where he developed a solid foundation in biological sciences. He later pursued an M.Phil. in Clinical Neuroscience at the University of Cambridge, UK, which furthered his understanding of the cellular mechanisms underlying diseases and therapies. Dr. Inthanon earned his Ph.D. in Biology from Chiang Mai University in 2015, specializing in biotechnology and biochemistry, with a focus on human and animal cell culture systems. His diverse educational background has enabled him to combine basic biological research with applied studies in the biomedical and biotechnological fields. Dr. Inthanon’s interdisciplinary education and training make him well-equipped to investigate the molecular and cellular effects of biomaterials, natural products, and therapies, making significant contributions to the field of cell biology and tissue engineering.

Experience:

Dr. Kewalin Inthanon has extensive experience as an academic lecturer at the Department of Biotechnology, Faculty of Science and Technology, Thammasat University, Lampang Campus, Thailand, since 2016. His academic work involves teaching and guiding students in the fields of biotechnology and biochemistry. Prior to his current role, Dr. Inthanon completed a postdoctoral fellowship in biomaterial and tissue engineering at Chiang Mai University from 2015 to 2016. This experience enabled him to specialize in bioengineering, stem cell research, and cellular responses to biomaterial scaffolds. His involvement in various collaborative research projects further honed his skills in experimental design and analysis, leading to numerous peer-reviewed publications. Additionally, Dr. Inthanon has played an essential role in managing and supervising projects focused on the development of natural products and biocompatible materials for therapeutic applications. His expertise in cell culture techniques, biomaterials, and natural products makes him a valuable asset to the research community.

Research Focus:

Dr. Kewalin Inthanon’s research primarily focuses on the intersection of biotechnology, biochemistry, and natural product science. His work explores the effects of plant extracts, drugs, natural compounds, and biomaterials on human cell cultures, including stem cells and cancer cells. He is particularly interested in the cellular responses to oxidative stress, cytotoxicity, cellular senescence, and the modulation of gene expression in the context of disease prevention and treatment. Dr. Inthanon’s research aims to unravel complex signaling pathways and the molecular mechanisms that underlie cellular activities when exposed to various bioactive substances. This research is particularly relevant in the fields of cancer therapy, aging, and regenerative medicine, where the therapeutic potential of natural products can provide novel approaches to disease treatment. Additionally, his work on biomaterials, especially in tissue engineering, emphasizes creating biocompatible scaffolds to support cellular growth and differentiation in medical applications.

Publications Top Notes:

  1. Regulation of adipocyte differentiation and lipid metabolism by novel synthetic chromenes exploring anti-obesity and broader therapeutic potential 🧬💪

  2. Cytotoxic Constituents of the Fruits of Garcinia schomburgkiana 🍊💥

  3. Collagen‐cellulose‐poly (l‐lactide) scaffold by electrospinning and plasma‐assisting fabrication for bone tissue engineering applications 🦴🔬

  4. Phytochemical Profiles and Anticancer Effects of Calophyllum inophyllum L. Extract Relating to Reactive Oxygen Species Modulation on Patient-Derived Cells from Breast and Lung Cancers 🌿🦠

  5. In vitro assessment of antioxidant and anti-aging properties of ethanol extracts from Amaranthus dubius, Perilla frutescens (L.) britton, and Phyllanthus emblica 🌱⏳

  6. Identification of highly potent α-glucosidase inhibitors from Garcinia schomburgkiana and molecular docking studies 🧪🧠

  7. Sequencerelated amplified polymorphism (SRAP) molecular marker: DNA fingerprinting studying on economic and agricultural earthworms in North of Thailand 🧬🐍

  8. Chemical Constituents of the Stem Bark of Bombax ceiba 🌳🔬

  9. Intrinsic Cellular Responses of Human Wharton’s Jelly Mesenchymal Stem Cells Influenced by O2-Plasma-Modified and Unmodified Surface of Alkaline-Hydrolyzed 2D and 3D PCL Scaffolds 🔬⚙️

  10. Kluai Hom-Thong, biofermented solution, effective microorganism, banana, disease resistance 💡

Conclusion

Dr. Kewalin Inthanon is highly deserving of the Best Researcher Award. His innovative approach to research, combined with his impressive publication record, leadership in academia, and interdisciplinary expertise, make him an exceptional candidate. His focus on biotechnology, biochemistry, and natural products holds significant potential for advancing therapeutic and scientific advancements, particularly in the areas of aging, cancer, and stem cell research.

Xiao-Jun Du | Lipid Signaling Biology | Best Researcher Award

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Prof. Dr. Xiao-Jun Du | Lipid Signaling Biology | Best Researcher Award

Prof. Dr. Xiao-Jun Du , Xi’an Jiaotong University Health Science CenterBaker Heart and Diabetes Institute , China

Professor Xiao-Jun Du is a prominent researcher currently affiliated with Xi’an Jiaotong University in China and the Baker Heart and Diabetes Institute in Australia. With a background in medicine and a PhD from the University of Edinburgh, he has built a distinguished career in the field of cardiovascular research. His expertise spans across heart failure, cardiac inflammation, arrhythmias, fibrosis, and metabolism. Professor Du has made significant contributions to understanding heart diseases, pioneering mouse cardiology research in Australia. Over the years, he has published 269 scientific papers, including 234 in peer-reviewed journals, with an H-index of 63. He is a highly respected reviewer and has supervised more than 60 postgraduate students. His work has made a major impact on cardiovascular medicine, specifically in the areas of heart failure and metabolic therapies.

Publication Profile:

Scopus

Strengths for the Award:

Professor Xiao-Jun Du is highly deserving of the Research for Best Researcher Award due to his outstanding contributions to cardiovascular science, particularly in the areas of heart failure, cardiac inflammation, arrhythmias, and fibrosis. His pioneering work in mouse cardiology and his research on the role of metabolism in heart disease have garnered significant recognition. With 269 publications, 234 of which are in SCI-indexed journals, and over 13,000 citations, his work has a significant impact in the scientific community. His H-index of 63 reflects the importance and relevance of his research. Additionally, Professor Du’s mentorship of over 60 postgraduate students demonstrates his commitment to fostering the next generation of researchers. His invitation to review around 40 manuscripts annually further solidifies his standing as an expert and thought leader in his field.

Areas for Improvements:

Despite his numerous achievements, Professor Du could benefit from further international collaborations to expand the global impact of his research. Although his work has been influential, engaging with broader research initiatives and interdisciplinary projects could enhance his work’s application in clinical settings and improve translational research in cardiovascular diseases. A more direct focus on public health applications of his research might help to bridge the gap between laboratory findings and real-world medical advancements.

Education:

Professor Xiao-Jun Du’s educational journey began with his medical degree from Chongqing Medical University, followed by a Master of Medicine from Xi’an Medical University. He furthered his academic path by obtaining a PhD from the University of Edinburgh. His diverse training equipped him with deep knowledge in the fields of cardiology, medical research, and therapeutic interventions. His doctoral work laid the foundation for his future contributions to cardiovascular science. His ongoing academic roles, including his current position as a Professor at Xi’an Jiaotong University and Honorary Research Fellow at the Baker Heart and Diabetes Institute, reflect his commitment to both education and groundbreaking research.

Experience:

Professor Xiao-Jun Du has an extensive academic and research career. He has held several prestigious positions, including Head of the Experimental Cardiology Laboratory and Mouse Cardiology Research Platform at the Baker Heart and Diabetes Institute in Melbourne. He also served as a Senior Research Fellow with the Australian National Health & Medical Research Council (NHMRC). Currently, he is a Professor at Xi’an Jiaotong University in China. Throughout his career, Professor Du has made significant strides in the study of heart failure, arrhythmias, and cardiac fibrosis. He has worked on groundbreaking research related to heart diseases and metabolic disorders. As a highly regarded researcher, he has been invited to review over 40 journal manuscripts annually, maintaining his position as a leading expert in his field. In addition, he has mentored and guided over 60 postgraduate students and research trainees.

Research Focus:

Professor Xiao-Jun Du’s research primarily focuses on the pathophysiology of heart failure, cardiac inflammation, and metabolic disorders. His work investigates the mechanisms underlying heart disease, particularly focusing on cardiac fibrosis, remodelling, arrhythmias, and the role of metabolism in cardiac function. He has pioneered research on the mouse cardiology model, which has become a critical tool for studying heart failure and other cardiovascular diseases. Professor Du’s current research also explores the interaction between β-adrenergic and Hippo pathway signaling, the role of endothelial dysfunction in hypertension, and the effects of mitochondrial dysfunction in heart disease. His work is highly interdisciplinary, bridging molecular biology, cardiology, and therapeutic approaches. Additionally, he investigates how oxidative stress, inflammatory pathways, and cellular damage contribute to cardiovascular diseases and explores potential therapeutic strategies, including metabolic therapies for heart failure.

Publications Top Notes:

  1. “Cardiomyopathy characterizing and heart failure risk predicting by echocardiography in aged male mice” 📉🫀
  2. “Coupling of β-adrenergic and Hippo pathway signaling: Implications for heart failure pathophysiology and metabolic therapy” 🔄🧬
  3. “Nogo-B mediates endothelial oxidative stress and inflammation to promote coronary atherosclerosis in pressure-overloaded mouse hearts” 🧪❤️
  4. “New perspective on the mechanisms of cardiac fibrosis” 🔍🫀
  5. “Endothelial KCa3.1 and KCa2.3 Mediate S1P (Sphingosine-1-Phosphate)-Dependent Vasodilation and Blood Pressure Homeostasis” 🩸💉
  6. “Evaluation of Coenzyme Q10 (CoQ10) Deficiency and Therapy in Mouse Models of Cardiomyopathy” 💊🧬
  7. “Mitochondrial damage in a Takotsubo syndrome-like mouse model mediated by activation of β-adrenoceptor-Hippo signaling pathway” ⚡🫀
  8. “AGEs-RAGE-KCa3.1 pathway mediates palmitic acid-induced migration of PBMCs from patients with type 2 diabetes” 🧬🍔
  9. “YAP-galectin-3 signaling mediates endothelial dysfunction in angiotensin II-induced hypertension in mice” 🧪🧬
  10. “Hippo pathway activation mediates chemotherapy-induced anti-cancer effect and cardiomyopathy through causing mitochondrial damage and dysfunction” 🎗️🧠

Conclusion:

Professor Xiao-Jun Du’s extensive body of work and his dedication to advancing cardiovascular medicine make him a strong candidate for the Research for Best Researcher Award. His deep expertise, innovative contributions to heart failure and metabolic therapies, and his leadership in training the next generation of scientists highlight his qualifications. Given his remarkable academic achievements and influence in the field, he is an excellent choice for this prestigious award.